catechin has been researched along with Cancer of Colon in 116 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (8.62) | 18.2507 |
| 2000's | 58 (50.00) | 29.6817 |
| 2010's | 34 (29.31) | 24.3611 |
| 2020's | 14 (12.07) | 2.80 |
| Authors | Studies |
|---|---|
| Baggett, S; Cui, B; Hequet, V; Kennelly, EJ; Ma, C; Mori, S; Protiva, P; Weinstein, IB; Yang, H | 1 |
| Ali, S; Iram, S; Kim, J; Rahman, S | 1 |
| Bai, Y; Chen, X; Hu, Y; Li, X; Song, W; Wan, H; Wu, Z; Yuan, Y; Zhang, Y | 1 |
| Shi, C; Wang, S; Zhang, Z; Zhu, Q | 1 |
| Agarwal, S; Bhardwaj, P; Bhattacharjee, D; Chattopadhyay, D; Das, A; De, S; Ghosh, A; Ghosh, P; Hore, M; Ikbal, AMA; Karmakar, S; Mishra, S; Misra, S; Palit, P; Saha, KD; Srinivas, R; Tiwari, ON; Ubhadia, IB | 1 |
| Budriesi, R; Chiaino, E; Chiarini, A; Durante, M; Frosini, M; Gotti, R; Marzetti, C; Micucci, M | 1 |
| Peng, W; Xu, P; Yang, J; Yi, M; Yi, P; Zhang, S; Zhang, Z | 1 |
| Chen, W; Dai, Y; Guo, J; Huang, W; Li, K; Liao, X; Richardson, JJ; Shi, B; Xiao, G; Yu, K | 1 |
| Azevedo, L; Cruz, AG; Cruz, TM; de Almeida, LA; do Carmo, MAV; Escher, GB; Fidelis, M; Granato, D; Kaneshima, T; Marques, MB; Nunes, JB; Rocha, RS; Santos, JS | 1 |
| Gönel, A; Karaoğul, E; Koyuncu, İ; Temiz, E; Uyar, Z | 1 |
| Basu, S; Bhattacharjee, P; Bhattacharya, R; Chatterjee, R; Chatterji, U; Giri, AK; Mandal, AKA; Mukhopadhyay, A | 1 |
| Hassan, ESG; Hassanein, NM; Sayed Ahmed, HM | 1 |
| Ding, F; Yang, S | 1 |
| Afzal, SM; Ali, N; Islam, J; Rashid, S; Shree, A; Sultana, S; Vafa, A | 1 |
| Chen, Y; Feng, N; Feng, Y; Li, S; Ouyang, Y; Wu, Q; Zhang, L; Zhao, K | 1 |
| Bharali, MK; Borah, G | 1 |
| Guo, X; Ni, J; Wang, H; Wang, X; Zhou, T | 1 |
| Elahl, HMS; Hassan, ESG; Hassanein, NMA; Hegab, AM | 1 |
| Bai, W; Chen, T; Huang, W; Huang, Y; Li, X; Peng, L; Shi, L; Tan, Q | 1 |
| Ha, T; Kim, CH; Lee, BS; Lee, J; Lee, SH; Lou, Z | 1 |
| Butt, MS; Imran, A; Imran, M; Mubarak, MS; Ramadan, MF; Rauf, A; Xiao, H | 1 |
| Chen, J; Chen, Z; Di, L; Hu, L; Huang, J; Li, J; Qiao, H; Wang, H; Wang, R; Yang, M | 1 |
| Angelino, D; Bagatta, M; De Nicola, GR; Farabegoli, F; Gennari, L; Iori, R; Ninfali, P; Orlandi, M; Papi, A | 1 |
| Alcarraz-Vizán, G; Cascante, M; Marín, S; Sánchez-Tena, S; Torres, JL | 1 |
| Ahn, S; Kim, DW; Kim, SH; Koh, D; Lee, YH; Lim, Y; Shin, SY; Yoon, H | 1 |
| Bravo, L; Cordero-Herrera, I; Goya, L; Martín, MA; Ramos, S | 1 |
| Akao, Y; Iwasaki, J; Kumazaki, M; Noguchi, S; Shinohara, H; Yamada, N; Yasui, Y | 1 |
| Cascante, M; Centelles, JJ; Dudeja, PK; Sánchez-Tena, S; Vizán, P | 1 |
| Berkelhammer, J; Hopkins, S; Loo, G; Murphy, A; Testa, K | 1 |
| Knackstedt, RW; Morris, J; Moseley, VR; Wargovich, MJ | 1 |
| Kala, R; Saldanha, SN; Tollefsbol, TO | 1 |
| Bastian, SE; Bindon, KA; Cheah, KY; Howarth, GS; Kennedy, JA | 1 |
| Arakawa, Y; Ikemoto, T; Imura, S; Ishikawa, D; Iwahashi, S; Morine, Y; Saito, Y; Shimada, M; Wubetu, GY; Yamada, S | 1 |
| Alvarez-Barrientos, A; Centeno, F; Cerezo-Guisado, MI; Cuenda, A; Lorenzo, MJ; Martín-Serrano, MA; Risco, A; Zur, R | 1 |
| Cabang, AB; Coleman, K; Garrett-Mayer, E; Morris, J; Moseley, VR; Wargovich, MJ; Wei, W | 1 |
| Kim, SW; Moon, JH; Park, SY | 1 |
| Adachi, S; Joe, AK; Kozawa, O; Matsushima-Nishiwaki, R; Maxfield, FR; Moriwaki, H; Nagao, T; Shimizu, M; To, S; Weinstein, IB | 1 |
| Cabezas-Herrera, J; García-Cánovas, F; Navarro-Perán, E; Rodríguez-López, JN; Sánchez-Del-Campo, L | 1 |
| Chen, KY; Gosslau, A; Liu, AY; Lu, J | 1 |
| Adachi, S; Hata, K; Hirose, Y; Moriwaki, H; Sakai, H; Shimizu, M; Shirakami, Y; Tanaka, T; Tsurumi, H | 1 |
| Katdare, M; Telang, N | 1 |
| Adachi, S; Kozawa, O; Matsushima-Nishiwaki, R; Moriwaki, H; Natsume, H; Shimizu, M; Shirakami, Y; To, S; Weinstein, IB; Yamauchi, J | 1 |
| Li, YQ; Sun, ZY; Yang, XY; Yuan, JH; Zhang, ZM | 1 |
| Ha, J; Hwang, JT; Kwon, DY; Lee, YK; Park, IJ; Park, OJ | 1 |
| Chen, XQ; Li, MS; Song, YG; Wu, JB; Yang, XQ | 1 |
| Duthie, GG; Kyle, JA; Little, J; McNeill, G; Sharp, L | 1 |
| Dashwood, RH; Larsen, CA | 2 |
| Bisson, WH; Dashwood, RH; Larsen, CA | 1 |
| Kang, L; Ren, G; Tian, K; Wang, Z; Xu, G; Xu, X; Yu, W; Yuan, H | 1 |
| Ahn, SG; Choi, HS; Kim, SA; Tran, PL; Yoon, JH | 1 |
| Brockmöller, J; Ettrich, T; Muche, R; Seeringer, A; Seufferlein, T; Stingl, JC; Wiedom, M | 1 |
| Guo, DL; Mu, Y; Wang, T; Wu, B; Wu, Y; Zhang, XM; Zhou, F; Zhou, H | 1 |
| Antonacci, D; Bizzarri, M; Cucina, A; D'Anselmi, F; Dinicola, S; Lisi, E; Pasqua, G; Pasqualato, A; Proietti, S | 1 |
| Chiou, YS; Ho, CT; Ma, NJ; Pan, MH; Sang, S; Wang, YJ | 1 |
| Guan, F; Ju, J; Li, G; Liu, AB; Sun, Y; Yang, CS; Yang, Z | 1 |
| Alotaibi, A; Anderson, D; Bhatnagar, P; Gupta, KC; Najafzadeh, M | 1 |
| Kim, D; Kim, K; Mollah, ML | 1 |
| Abgaryan, N; Aronson, WJ; Carpenter, CL; de Oliveira, DM; Heber, D; Henning, SM; Lee, RP; Vicinanza, R; Wang, P; Zhang, Y | 1 |
| Kim, N; Lee, HS; Na, HK; Park, J; Surh, YJ; Yum, HW; Zhong, X | 1 |
| Jiang, B; Tan, X; Zhang, Y; Zhou, D | 1 |
| Chan, K; Feng, WY; Johnston, J; Naasani, I; Oh-Hara, T; Oh-Hashi, F; Tsuruo, T | 1 |
| Bai, N; Ho, CT; Hong, J; Li, C; Lu, H; Meng, X; Patten, C; Sang, S; Sheng, S; Winnik, B; Yang, CS | 1 |
| Stein, J; Turchanowa, L; Wolter, F | 1 |
| Chen, C; Hebbar, V; Hu, R; Kong, AN; Owuor, ED; Shen, G | 1 |
| Ho, CT; Hong, J; Hou, Z; Huang, MT; Lambert, JD; Rosen, RT; Ryu, JH; Sang, S; Stark, RE; Tian, S; Yang, CS | 1 |
| Akizawa, T; Asai, T; Matsukawa, M; Oku, N; Uchida, T; Yamakawa, S | 1 |
| Certa, U; Gissel, C; Hescheler, J; McLoughlin, P; Roengvoraphoj, M; Sachinidis, A | 1 |
| Baek, SJ; Eling, TE; Jackson, FR; Kim, JS; Lee, SH; McEntee, MF | 1 |
| He, MR; Huang, W; Lai, ZS; Wang, YD; Xu, G; Zhang, WM; Zhang, YL | 1 |
| Deguchi, A; Kopelovich, L; Lim, JT; Moriwaki, H; Shimizu, M; Weinstein, IB | 1 |
| Deguchi, A; Hara, Y; Moriwaki, H; Shimizu, M; Weinstein, IB | 1 |
| Al-Fageeh, M; Carter, O; Dashwood, RH; Dashwood, WM; Li, Q | 1 |
| Drewe, J; Porath, D; Riegger, C; Schwager, J | 1 |
| Debnam, ES; Kuhnle, GG; Lee, SY; Munerol, B; Pannala, AS; Pollard, S; Rice-Evans, C; Spencer, JP; Youdim, KA | 1 |
| Deguchi, A; Joe, AK; Mckoy, JF; Moriwaki, H; Shimizu, M; Weinstein, IB | 1 |
| Dixon, DA; Muga, SJ; Peng, G; Smith, TJ; Wargovich, MJ | 1 |
| Baum, M; Eisenbrand, G; Janzowski, C; Schaefer, S | 1 |
| Guo, YT; Li, YQ; Sun, ZY; Wang, M; Yang, XY; Yuan, JH; Zhang, Y; Zhao, WP; Zhu, Q | 1 |
| Cascante, M; Centelles, JJ; Jiménez, A; Juliá, L; Lozano, C; Torres, JL; Touriño, S | 1 |
| Baik, HW; Ha, J; Hwang, JT; Kim, YM; Lee, SK; Park, IJ; Park, OJ | 1 |
| Benghuzzi, H; May, M; Norwood, AA; Tan, M; Tucci, M | 1 |
| Bergerat, JP; Gossé, F; Guyot, S; Mann, A; Raul, F; Roussi, S; Schoenfelder, A; Seiler, N | 1 |
| Bhattacharjee, S; Bhattacharya, S; Das, RK; Ghosh, S; Sengupta, A | 1 |
| Eisenbrand, G; Jakobs, S; Kern, M; Marko, D; Ngiewih, Y; Pahlke, G | 1 |
| Coppola, D; Helm, J; Kumar, N; Malafa, M; Shibata, D | 1 |
| Gao, YT; Yang, CS; Yu, MC; Yuan, JM | 1 |
| Benghuzzi, H; Norwood, AA; Tucci, M | 1 |
| Bailey, GS; Carter, O; Dashwood, RH; Dashwood, WM; Fischer, KA; Löhr, CV; Orner, GA; Pereira, CB; Wang, R; Williams, DE | 1 |
| Li, YQ; Yang, XY; Yuan, JH | 1 |
| Gopalakrishnan, A; Hebbar, V; Khor, TO; Kong, AN; Nair, S; Shen, G; Xu, C; Yu, S | 1 |
| Bailey, GS; Dashwood, RH; Dashwood, WM; Fischer, KA; Löhr, CV; Louderback, M; Nakagama, H; Pereira, CB; Wang, R; Williams, DE | 1 |
| Tachibana, H; Umeda, D; Yamada, K; Yano, S | 1 |
| Akagi, K; Hara, Y; Hirose, M; Hoshiya, T; Ito, N; Takahashi, S | 1 |
| Stammler, G; Volm, M | 1 |
| Dashwood, R; Hasaniya, N; Hernaez, J; Xu, M; Youn, K | 1 |
| Aliaga, C; Balentine, DA; Boone, CW; Kelloff, GJ; Pittman, B; Reinhardt, J; Rivenson, A; Steele, VE; Weisburger, JH; Zang, E | 1 |
| Kim, K; Liao, J; Yang, CS; Yang, GY; Yurkow, EJ | 1 |
| Naasani, I; Seimiya, H; Tsuruo, T | 1 |
| Chen, KY; Chen, ZP; Ho, CT; Schell, JB | 1 |
| Futakuchi, M; Hirose, M; Iwata, H; Ogawa, K; Shibutani, M; Shirai, T; Takahashi, S; Toyoda, K; Uneyama, C | 1 |
| Dashwood, RH; Xu, M | 1 |
| Casalini, C; Clifford, M; Copeland, E; De Filippo, C; Dolara, P; Lodovici, M; Xu, X | 1 |
| Hayakawa, S; Isemura, M; Kimura, T; Minami, T; Saeki, K; Sazuka, M | 1 |
| Ahn, BW; Bucana, CD; Chay, KO; Ellis, LM; Gallick, GE; Jung, YD; Kim, MS; Liu, W; Shin, BA | 1 |
| Akagi, K; Hirose, M; Hoshiya, T; Mizoguchi, Y; Nakamura, A; Shirai, T | 1 |
| Hori, H; Kamishimoto, M; Kitagawa, Y; Kumagai, A; Nagasawa, H; Uesato, S | 1 |
| Diamandis, EP; Goldberg, DM; Grass, L; Levesque, M; Soleas, GJ | 1 |
| Belfi, CA; Berger, SJ; Gosky, DM; Gupta, S; Mukhtar, H | 1 |
| August, DA; Ho, CT; Hong, J; Smith, TJ; Yang, CS | 1 |
| Carnésecchi, S; Coehlo, D; Gossé, F; Lazarus, SA; Raul, F; Schneider, Y | 1 |
| Hara, Y; Hasegawa, J; Isemura, M; Kishimoto, Y; Kohri, T; Miura, N; Ohishi, T; Shiota, G | 1 |
| Lu, H; Wang, C; Wu, H; Ye, J; Zhou, J | 1 |
| Cooney, RV; Custer, LJ; Dashwood, RH; Franke, AA; Tanaka, Y; Xu, M | 1 |
| Bugianesi, R; Maiani, G; Salucci, M; Stivala, LA; Vannini, V | 1 |
| Akachi, S; Hagiwara, N; Inagake, M; Kim, M; Kitao, Y; Kuwata, K; Okuzumi, J; Takahashi, T; Tateishi, M; Yamane, T | 1 |
1 review(s) available for catechin and Cancer of Colon
| Article | Year |
|---|---|
Green tea polyphenols in the prevention of colon cancer.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Catechin; Clinical Trials, Phase I as Topic; Colonic Neoplasms; Flavonoids; Humans; Mice; Phenols; Polyphenols; Rats; Tea | 2007 |
2 trial(s) available for catechin and Cancer of Colon
| Article | Year |
|---|---|
Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population.
Topics: Adenoma; Aged; Aged, 80 and over; Camellia sinensis; Catechin; Colonic Neoplasms; Colonoscopy; Dietary Supplements; Double-Blind Method; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Placebos; Plant Extracts | 2011 |
Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Camellia sinensis; Catechin; Cell Proliferation; Chromatography, High Pressure Liquid; Colonic Neoplasms; Gallic Acid; HCT116 Cells; Hippurates; Humans; Hydroxybenzoates; Lactones; Male; Middle Aged; Phenylacetates; Prostatic Neoplasms; Tea | 2013 |
113 other study(ies) available for catechin and Cancer of Colon
| Article | Year |
|---|---|
New bioactive polyphenols from Theobroma grandiflorum ("cupuaçu").
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Catechin; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; French Guiana; Glycosides; Humans; Inhibitory Concentration 50; Malvaceae; Molecular Structure; Picrates; Seeds; Tumor Cells, Cultured | 2003 |
Tetranectin targeting by epigallocatechin gallate suppresses colon cancer cell proliferation.
Topics: Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; Lectins, C-Type; Plasminogen | 2022 |
Physicochemical and Colon Cancer Cell Inhibitory Properties of Theabrownins Prepared by Weak Alkali Oxidation of Tea Polyphenols.
Topics: Alkalies; Apoptosis; Catechin; Colonic Neoplasms; Humans; Oxidation-Reduction; Polyphenols; Tea | 2022 |
Epigallocatechin-3-gallate inhibits the formation of neutrophil extracellular traps and suppresses the migration and invasion of colon cancer cells by regulating STAT3/CXCL8 pathway.
Topics: Catechin; Colonic Neoplasms; Deoxyribonuclease I; Extracellular Traps; Humans; Neutrophils; STAT3 Transcription Factor; Tea; Tumor Necrosis Factor-alpha | 2023 |
Validation of antioxidant, antiproliferative, and in vitro anti-rheumatoid arthritis activities of epigallo-catechin-rich bioactive fraction from Camellia sinensis var. assamica, Assam variety white tea, and its comparative evaluation with green tea fract
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Rheumatoid; Camellia sinensis; Catechin; Colonic Neoplasms; Mammals; Phytochemicals; Tea | 2022 |
Apoptotic-Induced Effects of
Topics: Acacia; Adenocarcinoma; Animals; Apoptosis; Caspase 3; Caspase 9; Catechin; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Plant Extracts; Rats; Reactive Oxygen Species | 2020 |
Integrated transcriptomic and metabolomic analyses to characterize the anti-cancer effects of (-)-epigallocatechin-3-gallate in human colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Proliferation; Colonic Neoplasms; HT29 Cells; Humans; Metabolomics; Transcriptome | 2020 |
Self-Assembled Metal-Phenolic Nanoparticles for Enhanced Synergistic Combination Therapy against Colon Cancer.
Topics: Animals; Antineoplastic Agents; Catechin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Synergism; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Phenols; Samarium | 2019 |
Polyphenols of jabuticaba [Myrciaria jaboticaba (Vell.) O.Berg] seeds incorporated in a yogurt model exert antioxidant activity and modulate gut microbiota of 1,2-dimethylhydrazine-induced colon cancer in rats.
Topics: 1,2-Dimethylhydrazine; alpha-Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Catechin; Colonic Neoplasms; Gastrointestinal Microbiome; Humans; Hydrolyzable Tannins; Male; Myrtaceae; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Rats, Wistar; Seeds; Yogurt | 2021 |
Pistachio Green Hull Extract Induces Apoptosis through Multiple Signaling Pathways by Causing Oxidative Stress on Colon Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Survival; Colonic Neoplasms; DNA Damage; Drug Screening Assays, Antitumor; Fatty Acids, Nonesterified; Gallic Acid; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; HT29 Cells; Humans; Oxidative Stress; Phenols; Pistacia; Plant Extracts; Signal Transduction; Tandem Mass Spectrometry | 2021 |
Theaflavin-Containing Black Tea Extract: A Potential DNA Methyltransferase Inhibitor in Human Colon Cancer Cells and Ehrlich Ascites Carcinoma-Induced Solid Tumors in Mice.
Topics: Animals; Ascites; Biflavonoids; Carcinoma; Catechin; Colonic Neoplasms; Epigenesis, Genetic; Humans; Mice; Plant Extracts; Tea | 2021 |
Probing the chemoprevention potential of the antidepressant fluoxetine combined with epigallocatechin gallate or kaempferol in rats with induced early stage colon carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Dimethylhydrazines; Fluoxetine; Kaempferols; Male; Phytotherapy; Rats, Sprague-Dawley | 2021 |
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Topics: Animals; Apoptosis; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Female; Hedgehog Proteins; Humans; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
Amelioration of N,N'-dimethylhydrazine induced colon toxicity by epigallocatechin gallate in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Colonic Neoplasms; Disease Models, Animal; Humans; Male; Rats; Rats, Wistar | 2021 |
Effect of lotus seedpod oligomeric procyanidins on AGEs formation in simulated gastrointestinal tract and cytotoxicity in Caco-2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Catechin; Colonic Neoplasms; Digestion; Gastrointestinal Tract; Gene Expression; Glycation End Products, Advanced; Humans; Inflammation; Nelumbo; Pepsin A; Proanthocyanidins; Reactive Oxygen Species; Seeds; Tocopherols; Trypsin Inhibitors | 2021 |
Green tea catechins in combination with irinotecan attenuates tumorigenesis and treatment-associated toxicity in an inflammation-associated colon cancer mice model.
Topics: Animals; Carcinogenesis; Catechin; Colonic Neoplasms; Humans; Inflammation; Irinotecan; Mice; Tea | 2021 |
Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Chromosomal Instability; Colonic Neoplasms; DNA Mismatch Repair; Humans; Tea | 2018 |
Chemopreventive effect of sulindac in combination with epigallocatechin gallate or kaempferol against 1,2-dimethyl hydrazine-induced preneoplastic lesions in rats: A Comparative Study.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; beta Catenin; Carcinogens; Catechin; Colonic Neoplasms; Cyclooxygenase 2; Down-Regulation; Drug Therapy, Combination; Kaempferols; Male; Nitric Oxide; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats, Sprague-Dawley; Sulindac; Thiobarbituric Acid Reactive Substances | 2018 |
Structure-Activity Relationship Analysis on Antioxidant and Anticancer Actions of Theaflavins on Human Colon Cancer Cells.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Biflavonoids; Camellia sinensis; Catechin; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Humans; Plant Extracts; Reactive Oxygen Species; Structure-Activity Relationship; Tea | 2019 |
Identification of epithelial-specific ETS-1 (ESE-1) as a tumor suppressor and molecular target of green tea compound, EGCG.
Topics: Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Caco-2 Cells; Catechin; Cell Line, Tumor; Cell Movement; Cell Nucleus; Colonic Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; HT29 Cells; Humans; Mice; Nuclear Localization Signals; Proto-Oncogene Proteins c-ets; Transcription Factors; Xenograft Model Antitumor Assays | 2019 |
Inhibitory effect of black tea (Camellia sinensis) theaflavins and thearubigins against HCT 116 colon cancer cells and HT 460 lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Biflavonoids; Camellia sinensis; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Synergism; HCT116 Cells; Humans; Lung Neoplasms; Polyphenols; Tea | 2019 |
Enhanced anti-colon cancer efficacy of 5-fluorouracil by epigallocatechin-3- gallate co-loaded in wheat germ agglutinin-conjugated nanoparticles.
Topics: Animals; Apoptosis; Catechin; Colonic Neoplasms; Fluorouracil; HT29 Cells; Humans; Mice; Nanoconjugates; Neovascularization, Pathologic; Wheat Germ Agglutinins; Xenograft Model Antitumor Assays | 2019 |
Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells.
Topics: Apigenin; Apoptosis; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Humans; Isothiocyanates; Mitochondria; Reactive Oxygen Species | 2013 |
Epicatechin gallate impairs colon cancer cell metabolic productivity.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Proliferation; Colonic Neoplasms; Glucose; Glucosephosphate Dehydrogenase; HT29 Cells; Humans; Pentose Phosphate Pathway; Tea; Transketolase; Vitis | 2013 |
Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases.
Topics: Antineoplastic Agents; Aurora Kinases; Benzopyrans; Binding Sites; Blotting, Western; Catechin; Cell Line, Tumor; Cell Survival; Chalcones; Colonic Neoplasms; Humans; Inhibitory Concentration 50; Protein Binding | 2013 |
Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Down-Regulation; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; Tea; Tumor Suppressor Protein p53 | 2013 |
Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Stilbenes; Xanthones | 2013 |
Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1.
Topics: Adenocarcinoma; Alkaline Phosphatase; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Butyric Acid; Catechin; Cell Differentiation; Cell Membrane; Cell Proliferation; Colonic Neoplasms; Histamine Antagonists; Humans; Membrane Microdomains; Monocarboxylic Acid Transporters; Polyphenols; Tea; Tumor Cells, Cultured | 2013 |
Impact of antioxidants on the ability of phenolic phytochemicals to kill HCT116 colon cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Catechin; Cell Line, Tumor; Colonic Neoplasms; Curcumin; DNA Damage; Drug Interactions; Gene Expression; HCT116 Cells; Heme Oxygenase-1; HT29 Cells; Humans; Iron Chelating Agents | 2014 |
Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells.
Topics: Base Sequence; Catechin; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Primers; HCT116 Cells; Histone Deacetylases; Humans; Proteolysis; Real-Time Polymerase Chain Reaction; Tea | 2013 |
Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butyric Acid; Catechin; Cell Cycle Checkpoints; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Epigenesis, Genetic; HCT116 Cells; HT29 Cells; Humans; Signal Transduction; Tumor Cells, Cultured | 2014 |
Low molecular weight procyanidins from grape seeds enhance the impact of 5-Fluorouracil chemotherapy on Caco-2 human colon cancer cells.
Topics: Antineoplastic Agents; Antioxidants; Biflavonoids; Caco-2 Cells; Catechin; Cell Survival; Colonic Neoplasms; Drug Synergism; Fluorouracil; Grape Seed Extract; Humans; Molecular Weight; Proanthocyanidins | 2014 |
Epigallocatechin gallate hinders human hepatoma and colon cancer sphere formation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; Hep G2 Cells; Humans; Liver Neoplasms; Neoplastic Stem Cells; Tea | 2016 |
Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Food Handling; HEK293 Cells; Humans; Isoenzymes; MAP Kinase Signaling System; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Tea | 2015 |
Reduction in promotor methylation utilizing EGCG (epigallocatechin-3-gallate) restores RXRα expression in human colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colonic Neoplasms; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Retinoid X Receptor alpha; Tea | 2016 |
Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors.
Topics: Anticarcinogenic Agents; Apoptosis; Autophagy; Catechin; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2016 |
(-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colonic Neoplasms; Endosomes; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Ubiquitin | 2008 |
The anti-inflammatory and anti-cancer properties of epigallocatechin-3-gallate are mediated by folate cycle disruption, adenosine release and NF-kappaB suppression.
Topics: Adenosine; Anticarcinogenic Agents; Antioxidants; Caco-2 Cells; Catechin; Colonic Neoplasms; Folic Acid; Humans; I-kappa B Proteins; Leucovorin; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-akt; Tumor Necrosis Factor-alpha; Vitamin B Complex | 2008 |
PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate.
Topics: Biflavonoids; Caco-2 Cells; Catechin; Colonic Neoplasms; Enzyme Induction; Flavonoids; Gallic Acid; Gene Expression Regulation; Humans; Phenols; Polyphenols; RGS Proteins; Tea; Time Factors | 2008 |
(-)-Epigallocatechin gallate suppresses azoxymethane-induced colonic premalignant lesions in male C57BL/KsJ-db/db mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinoma; Catechin; Cholesterol; Colonic Neoplasms; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Insulin; Intestinal Mucosa; Leptin; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Receptor, IGF Type 1; Triglycerides | 2008 |
Novel cell culture model for prevention of carcinogenic risk in familial adenomatous polyposis syndrome.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Catechin; Cell Line; Colonic Neoplasms; Eflornithine; Eicosapentaenoic Acid; Genes, APC; Mice; Mice, Inbred C57BL; Mutation | 2009 |
(-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells.
Topics: Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; ErbB Receptors; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-cbl; Pyridines; Serine | 2009 |
Modulation of NRF2 and UGT1A expression by epigallocatechin-3-gallate in colon cancer cells and BALB/c mice.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Caco-2 Cells; Catechin; Colonic Neoplasms; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Green tea catechin controls apoptosis in colon cancer cells by attenuation of H2O2-stimulated COX-2 expression via the AMPK signaling pathway at low-dose H2O2.
Topics: Acetylcysteine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Apoptosis; Blotting, Western; Catechin; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Free Radical Scavengers; HT29 Cells; Humans; Hydrogen Peroxide; Oxidants; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Ribonucleotides; Signal Transduction; Tea; Tumor Suppressor Protein p53 | 2009 |
[Effects of epigallocatechin-3-gallate on the proliferation of colonic cancer cell line SW620 and PAK1 gene expression].
Topics: Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; p21-Activated Kinases | 2009 |
Dietary flavonoid intake and colorectal cancer: a case-control study.
Topics: Aged; Body Mass Index; Case-Control Studies; Catechin; Colonic Neoplasms; Colorectal Neoplasms; Diet; Feeding Behavior; Female; Flavonoids; Flavonols; Humans; Male; Middle Aged; Polymorphism, Genetic; Rectal Neoplasms; Reference Values; Risk Factors; Scotland; Surveys and Questionnaires; Tea | 2010 |
Suppression of Met activation in human colon cancer cells treated with (-)-epigallocatechin-3-gallate: minor role of hydrogen peroxide.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Line, Tumor; Colonic Neoplasms; Humans; Hydrogen Peroxide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor | 2009 |
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
Topics: Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Gallic Acid; Humans; Kinetics; Models, Molecular; Phenols; Polyphenols; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Structure-Activity Relationship | 2009 |
Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Catechin; Colon; Colonic Neoplasms; Coloring Agents; Curcumin; Dimethylhydrazines; DNA Fragmentation; Drug Synergism; In Situ Nick-End Labeling; Indicators and Reagents; Male; Rats; Rats, Wistar; Rectum; Tea | 2010 |
(-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells.
Topics: Antineoplastic Agents; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; HCT116 Cells; Hepatocyte Growth Factor; Humans; Indoles; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Signal Transduction; Sulfonamides; Tea | 2010 |
Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Binding Sites; Breast Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Promoter Regions, Genetic; Time Factors; Transcription, Genetic; Transfection; Tumor Burden | 2010 |
Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro.
Topics: Anticarcinogenic Agents; Caspase 7; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Cytoskeleton; Extracellular Signal-Regulated MAP Kinases; Factor VIIa; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; NF-kappa B; Oligopeptides; Receptor, PAR-2; Signal Transduction | 2012 |
Antiproliferative and apoptotic effects triggered by Grape Seed Extract (GSE) versus epigallocatechin and procyanidins on colon cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biflavonoids; Caco-2 Cells; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Grape Seed Extract; Humans; Proanthocyanidins; Vitis | 2012 |
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice.
Topics: Acetates; Acetylation; Animals; Catechin; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Down-Regulation; Gene Expression; Humans; Male; Mice; Mice, Inbred ICR; Premedication; Signal Transduction | 2012 |
Deleterious effects of high concentrations of (-)-epigallocatechin-3-gallate and atorvastatin in mice with colon inflammation.
Topics: Animals; Atorvastatin; Azoxymethane; Catechin; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Heptanoic Acids; Leukotriene B4; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pyrroles; Rectum; Weight Loss | 2012 |
Tea phenols in bulk and nanoparticle form modify DNA damage in human lymphocytes from colon cancer patients and healthy individuals treated in vitro with platinum-based chemotherapeutic drugs.
Topics: Antineoplastic Agents; Antioxidants; Catechin; Cell Survival; Chemoprevention; Cisplatin; Colonic Neoplasms; DNA Damage; Flavonoids; Humans; Lymphocytes; Nanoparticles; Particle Size; Polymers; Reactive Oxygen Species; Tea | 2013 |
Induction of apoptosis of SW480 human colon cancer cells by (-)-epicatechin isolated from Bulnesia sarmienti.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Catechin; Cell Line, Tumor; Colonic Neoplasms; Fluorescent Dyes; Humans; Indoles; Microscopy, Fluorescence; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Stereoisomerism; Tumor Suppressor Protein p53; Zygophyllaceae | 2012 |
Oligonol inhibits dextran sulfate sodium-induced colitis and colonic adenoma formation in mice.
Topics: Adenoma; Animals; Antioxidants; Apoptosis; Carcinogenesis; Catechin; Cell Line; Colitis; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Dextran Sulfate; Humans; Inflammation; Interleukin-1beta; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Phenols; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2013 |
Changes in ceramide levels upon catechins-induced apoptosis in LoVo cells.
Topics: Apoptosis; Catechin; Ceramides; Colonic Neoplasms; Diacylglycerol Kinase; Humans; Kinetics; Tumor Cells, Cultured | 2002 |
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Female; Flavonoids; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Phenols; Polymers; Telomerase; Tumor Cells, Cultured; U937 Cells; Xenograft Model Antitumor Assays | 2003 |
Glucuronides of tea catechins: enzymology of biosynthesis and biological activities.
Topics: Animals; Arachidonic Acid; Catechin; Cells, Cultured; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cytosol; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Insecta; Intestinal Mucosa; Intestines; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Microsomes; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Species Specificity | 2003 |
Resveratrol-induced modification of polyamine metabolism is accompanied by induction of c-Fos.
Topics: Acetyltransferases; Adenocarcinoma; Adenosylmethionine Decarboxylase; Anticarcinogenic Agents; Base Sequence; Caco-2 Cells; Catechin; Colonic Neoplasms; DNA Primers; Gene Expression Regulation; Humans; Ornithine Decarboxylase; Polyamines; Proto-Oncogene Proteins c-fos; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2003 |
Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Caspases; Catalase; Catechin; Colonic Neoplasms; Cytochrome c Group; DNA, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; HT29 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Urokinase-Type Plasminogen Activator | 2003 |
Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Biflavonoids; Biochemistry; Carcinoma, Squamous Cell; Catechin; Cell Division; Cells, Cultured; Colonic Neoplasms; Drug Evaluation, Preclinical; Ear Diseases; Edema; Esophageal Neoplasms; Female; Horseradish Peroxidase; Humans; Macrophages; Mice; Mice, Inbred Strains; Structure-Activity Relationship; Tea; Tetradecanoylphorbol Acetate; Toxicity Tests; Tumor Cells, Cultured | 2004 |
(-)-Epigallocatechin gallate inhibits membrane-type 1 matrix metalloproteinase, MT1-MMP, and tumor angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Cell Movement; Colonic Neoplasms; Endothelium, Vascular; Humans; Matrix Metalloproteinase 14; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Methylcholanthrene; Mice; Neovascularization, Pathologic; Sarcoma, Experimental; Tumor Cells, Cultured; Umbilical Veins; Urokinase-Type Plasminogen Activator | 2004 |
Transcriptional responses to epigallocatechin-3 gallate in HT 29 colon carcinoma spheroids.
Topics: Blotting, Western; Catechin; Colonic Neoplasms; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; ras GTPase-Activating Proteins; RNA, Messenger | 2004 |
Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells.
Topics: Antioxidants; Apoptosis; Catechin; Colonic Neoplasms; Cytokines; G1 Phase; Growth Differentiation Factor 15; HCT116 Cells; Humans; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Tea; Tumor Suppressor Protein p53 | 2004 |
[Effects of combined use of curcumin and catechin on cyclooxygenase-2 mRNA expression in dimethylhydrazine-induced rat colon carcinogenesis].
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Catechin; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Drug Synergism; Male; Random Allocation; Rats; Rats, Wistar; RNA, Messenger | 2005 |
(-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Caco-2 Cells; Caspase 3; Caspase 9; Caspases; Catechin; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cyclin D1; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; G1 Phase; Gene Expression Regulation; HT29 Cells; Humans; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Receptor, ErbB-2; Signal Transduction; Transcription Factor AP-1 | 2005 |
EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
Topics: Catechin; Cell Line, Tumor; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Receptor, IGF Type 1; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta2 | 2005 |
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
Topics: Anticarcinogenic Agents; beta Catenin; Cadherins; Catechin; Cell Line; Colonic Neoplasms; Colorectal Neoplasms; Genes, Reporter; Humans; Lysosomes; Recombinant Fusion Proteins; Signal Transduction; TCF Transcription Factors; Tea; Transcription Factor 7-Like 2 Protein | 2005 |
Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Chemokines; Colon; Colonic Neoplasms; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; HT29 Cells; Humans; Interleukin-8; Kinetics; Macrophage Inflammatory Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth.
Topics: Absorption; Animals; Apoptosis; Caco-2 Cells; Caspase 3; Caspases; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonoids; Gastrointestinal Tract; Humans; In Vitro Techniques; Mitogen-Activated Protein Kinase Kinases; Nitrosamines; Nitroso Compounds; Nitrous Acid; Phenols; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Nitrogen Species; Time Factors; Tyrosine | 2006 |
EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.
Topics: bcl-X Protein; Biotransformation; Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; DNA Fragmentation; Enzyme Induction; ErbB Receptors; Genes, erbB-2; Genes, Reporter; Humans; Immunoprecipitation; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transcription Factor AP-1 | 2005 |
Green tea polyphenol (-)-epigallocatechin-3-gallate inhibits cyclooxygenase-2 expression in colon carcinogenesis.
Topics: Blotting, Western; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Enzyme Induction; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; MAP Kinase Signaling System; NF-kappa B; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tea | 2006 |
Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines.
Topics: Antioxidants; Beverages; Caco-2 Cells; Caffeic Acids; Catechin; Cell Line; Chlorogenic Acid; Chromans; Colon; Colonic Neoplasms; DNA Damage; Flavonoids; Fruit; HT29 Cells; Humans; Malus; Oxidation-Reduction; Oxidative Stress; Phenols; Phlorhizin; Polyphenols; Rutin | 2006 |
[The role of NF-E2-related factor 2 in the induction of uridine 5'-diphosphate-glucuronosyltransferase 1A and its isoforms by epigallocatechin gallate in colon cancer cells].
Topics: Blotting, Western; Caco-2 Cells; Catechin; Colonic Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; HT29 Cells; Humans; Immunohistochemistry; Microscopy, Confocal; NF-E2-Related Factor 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Transfection | 2006 |
Electron-transfer capacity of catechin derivatives and influence on the cell cycle and apoptosis in HT29 cells.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Electron Spin Resonance Spectroscopy; Electron Transport; Humans; Kidney; Oxidation-Reduction | 2006 |
Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway.
Topics: AMP-Activated Protein Kinase Kinases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Colonic Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Membrane Proteins; Protein Kinases; Pyrazoles; Pyrimidines; Reactive Oxygen Species; Signal Transduction | 2007 |
Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.
Topics: Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Feasibility Studies; Fluorouracil; Plant Extracts; Tea; Treatment Outcome | 2006 |
Potentiation of apple procyanidin-triggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells.
Topics: Antineoplastic Agents; Apoptosis; Biflavonoids; Catechin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Humans; Hydrogen Peroxide; Malus; Neoplasm Metastasis; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Proanthocyanidins; Putrescine | 2006 |
Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways.
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Biflavonoids; Carotenoids; Catechin; Colon; Colonic Neoplasms; Cyclooxygenase 2; Lycopene; Male; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfides | 2006 |
Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells.
Topics: beta Catenin; Catechin; Cell Division; Colonic Neoplasms; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homeostasis; HT29 Cells; Humans; Quercetin; Wnt Proteins | 2006 |
Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study.
Topics: Biomarkers; Catechin; China; Colonic Neoplasms; Flavonoids; Humans; Male; Middle Aged; Phenols; Polyphenols; Risk Factors; Tea | 2007 |
A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Delayed-Action Preparations; Dose-Response Relationship, Drug; Fluorouracil; Humans; Phytotherapy; Plant Extracts; Treatment Outcome; Tumor Cells, Cultured | 2007 |
Comparison of white tea, green tea, epigallocatechin-3-gallate, and caffeine as inhibitors of PhIP-induced colonic aberrant crypts.
Topics: Animals; Anticarcinogenic Agents; Caffeine; Carcinogens; Catechin; Cell Division; Colon; Colonic Neoplasms; Humans; Imidazoles; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tea | 2007 |
Inhibition of epigallocatechin gallate on orthotopic colon cancer by upregulating the Nrf2-UGT1A signal pathway in nude mice.
Topics: Animals; Anticarcinogenic Agents; Catechin; Colonic Neoplasms; Glucuronosyltransferase; HT29 Cells; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; RNA, Messenger; Signal Transduction | 2007 |
Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.
Topics: Catechin; Cell Survival; Cellular Senescence; Colonic Neoplasms; Drug Synergism; HT29 Cells; Humans; Hydroxamic Acids; Isothiocyanates; Reactive Oxygen Species; Sulfoxides; Superoxide Dismutase; Thiocyanates; Transcription Factor AP-1; Transcriptional Activation | 2008 |
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
Topics: Animals; Anticarcinogenic Agents; beta Catenin; Caffeine; Carcinogens; Catechin; Colonic Neoplasms; Imidazoles; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Survival Analysis; Tea | 2008 |
Involvement of 67-kDa laminin receptor-mediated myosin phosphatase activation in antiproliferative effect of epigallocatechin-3-O-gallate at a physiological concentration on Caco-2 colon cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Caco-2 Cells; Catechin; Cell Cycle; Cell Proliferation; Colonic Neoplasms; HeLa Cells; Humans; Myosin-Light-Chain Phosphatase; Phosphorylation; Receptors, Laminin | 2008 |
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Catechin; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Intestinal Neoplasms; Intestine, Small; Kidney Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Models, Biological; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1993 |
Green tea catechins (EGCG and EGC) have modulating effects on the activity of doxorubicin in drug-resistant cell lines.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Catechin; Cell Division; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Flavonoids; Humans; Mice; Sarcoma 180; Tea; Tumor Cells, Cultured | 1997 |
Inhibitory activity of green and black tea in a free radical-generating system using 2-amino-3-methylimidazo[4,5-f]quinoline as substrate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Kinetics; Meat; Mutagens; NADPH-Ferrihemoprotein Reductase; Quinolines; Rats; Spin Labels; Tea | 1997 |
Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Catechin; Colonic Neoplasms; Flavonoids; Male; Phenols; Phytotherapy; Plant Extracts; Polymers; Rats; Rats, Inbred F344; Tea | 1998 |
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Catechin; Cell Division; Colonic Neoplasms; Humans; Lung Neoplasms; Superoxide Dismutase; Tea; Tumor Cells, Cultured | 1998 |
Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins.
Topics: Adenocarcinoma; Antineoplastic Agents; beta-Galactosidase; Catechin; Cell-Free System; Cellular Senescence; Colonic Neoplasms; Enzyme Inhibitors; Humans; Kinetics; Leukemia, Monocytic, Acute; Neoplasms; Tea; Telomerase; Telomere; Tumor Cells, Cultured | 1998 |
Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts.
Topics: Anticarcinogenic Agents; Apoptosis; Breast; Breast Neoplasms; Catechin; Cell Division; Cell Line, Transformed; Cells, Cultured; Colon; Colonic Neoplasms; Female; Fibroblasts; Gene Expression; Genes, fos; Genes, myc; Humans; Microscopy, Fluorescence; Neoplasms; RNA, Messenger; Tea; Tumor Cells, Cultured | 1998 |
Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.
Topics: Animals; Antioxidants; Carcinogens; Catechin; Colonic Neoplasms; Drug Antagonism; Imidazoles; Liver Neoplasms; Male; Quinolines; Rats; Rats, Inbred F344; Tannins | 1999 |
Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Chlorophyllides; Colon; Colonic Neoplasms; Drug Antagonism; Imidazoles; Indoles; Linoleic Acid; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 1999 |
Inhibition of 1,2-dimethylhydrazine-induced oxidative DNA damage in rat colon mucosa by black tea complex polyphenols.
Topics: 1,2-Dimethylhydrazine; 8-Hydroxy-2'-Deoxyguanosine; Alkylating Agents; Animals; Antioxidants; Carcinogens; Catechin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Deoxyguanosine; DNA Damage; Flavonoids; Intestinal Mucosa; Male; Phenols; Phytotherapy; Polymers; Polyphenols; Rats; Rats, Inbred F344; Tea | 2000 |
Tea catechins and related polyphenols as anti-cancer agents.
Topics: Anticarcinogenic Agents; Apoptosis; Catechin; Colonic Neoplasms; DNA Fragmentation; Flavonoids; Humans; Metalloendopeptidases; Phenols; Plant Extracts; Polymers; Stomach Neoplasms; Tea; Tumor Cells, Cultured; U937 Cells | 2000 |
EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells.
Topics: Animals; Apoptosis; Catechin; Colonic Neoplasms; Endothelial Growth Factors; Enzyme Activation; Humans; Immunohistochemistry; Lymphokines; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Tea; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Green tea catechins enhance tumor development in the colon without effects in the lung or thyroid after pretreatment with 1,2-Dimethylhydrazine or 2,2'-dihydroxy-di-n-propylnitrosamine in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Catechin; Colonic Neoplasms; Lung Neoplasms; Male; Nitrosamines; Organ Size; Phytotherapy; Rats; Rats, Inbred F344; Tea; Thyroid Neoplasms | 2001 |
Inhibition of green tea catechins against the growth of cancerous human colon and hepatic epithelial cells.
Topics: Beverages; Catechin; Cell Division; Colonic Neoplasms; Epithelial Cells; Humans; Liver Neoplasms; Tumor Cells, Cultured | 2001 |
Do wine polyphenols modulate p53 gene expression in human cancer cell lines?
Topics: Antioxidants; Breast Neoplasms; Caffeic Acids; Catechin; Colonic Neoplasms; Flavonoids; Fluoroimmunoassay; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Models, Structural; Phenols; Polymers; Quercetin; Resveratrol; Stilbenes; Time Factors; Tumor Cells, Cultured; Wine | 2001 |
Green tea constituent (--)-epigallocatechin-3-gallate inhibits topoisomerase I activity in human colon carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Catechin; Cell Division; Colonic Neoplasms; DNA Topoisomerases, Type II; Enzyme Inhibitors; Humans; Tea; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2001 |
Effects of purified green and black tea polyphenols on cyclooxygenase- and lipoxygenase-dependent metabolism of arachidonic acid in human colon mucosa and colon tumor tissues.
Topics: Antioxidants; Arachidonic Acid; Biflavonoids; Catechin; Colonic Neoplasms; Dinoprostone; Enzyme Inhibitors; Flavonoids; Humans; Intestinal Mucosa; Lipoxygenase; Microsomes; Phenols; Polymers; Prostaglandin-Endoperoxide Synthases; Tea; Tumor Cells, Cultured | 2001 |
Flavanols and procyanidins of cocoa and chocolate inhibit growth and polyamine biosynthesis of human colonic cancer cells.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Biflavonoids; Cacao; Catechin; Cell Division; Cell Survival; Colonic Neoplasms; Flavonoids; Humans; Kinetics; Phytotherapy; Plant Extracts; Polyamines; Proanthocyanidins; Tumor Cells, Cultured | 2002 |
Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Carcinogens; Catechin; Choristoma; Colon; Colonic Neoplasms; Drug Synergism; In Situ Nick-End Labeling; Incidence; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Sulindac; Tea | 2002 |
[Inhibitory effect of all-trans-retinoid and polyphenon-100 on microsatellite instability in a colon cancer line].
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Catechin; Cell Division; Colonic Neoplasms; DNA-Binding Proteins; Gene Expression; Humans; Lac Operon; Microsatellite Repeats; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Plasmids; Proto-Oncogene Proteins; RNA, Messenger; Transfection; Tretinoin; Tumor Cells, Cultured | 2002 |
Inhibition of colonic aberrant crypt formation by the dietary flavonoids (+)-catechin and hesperidin.
Topics: Animals; Anticarcinogenic Agents; Beverages; Carcinogens; Catechin; Cell Transformation, Neoplastic; Citrus; Colon; Colonic Neoplasms; Diet; Drug Evaluation, Preclinical; Food Analysis; Hesperidin; Intestinal Mucosa; Male; Molecular Structure; Quinolines; Rats; Rats, Inbred F344; Tea; Wine | 2002 |
Flavonoids uptake and their effect on cell cycle of human colon adenocarcinoma cells (Caco2).
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antioxidants; Catechin; Cell Cycle; Cell Division; Colonic Neoplasms; Flavonoids; Gallic Acid; Humans; Hydrogen Peroxide; Molecular Structure; Quercetin; Structure-Activity Relationship; Tea; Tumor Cells, Cultured | 2002 |
Inhibition of azoxymethane-induced colon carcinogenesis in rat by green tea polyphenol fraction.
Topics: Animals; Azoxymethane; Body Weight; Catechin; Colonic Neoplasms; Flavonoids; Male; Phenols; Plant Extracts; Polymers; Rats; Rats, Inbred F344; Tea; Time Factors | 1991 |