caseins has been researched along with Tooth Erosion in 51 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 16 (31.37) | 29.6817 |
2010's | 33 (64.71) | 24.3611 |
2020's | 2 (3.92) | 2.80 |
Authors | Studies |
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Alvitez-Temoche, D; Balbín-Sedano, G; Mayta-Tovalino, F; Pirca, K; Robles, G; Romero-Tapia, P | 1 |
Alexandria, AK; Cabral, LM; Canto, FMT; Ferreira, RDS; Justino, IBDS; Maia, LC; Pithon, MM; Rocha, GM | 1 |
Baumann, T; Carvalho, TS; Schmidt, C | 1 |
de Matos, LLM; Faraoni, JJ; Palma-Dibb, RG; Torres Toro, CV | 1 |
Attin, T; Cheng, H; Jiang, NW; Ye, XY; Yu, H; Zheng, HY | 1 |
Başlak, C; Dündar, A; Kuş, M; Şengün, A | 1 |
Cheng, H; Cheng, SL; Ye, XY; Yu, H; Zheng, HY | 1 |
Baumann, T; Carvalho, TS; Lussi, A; Schmidt, C; Sieber, KR | 1 |
Hara, AT; Lippert, F; Zero, DT | 1 |
Comar, LP; Magalhães, AC; Prestes, L; Rios, D; Salomão, PA; Souza, BM | 1 |
Huang, SB; Li, JY; Liu, Y; Wang, CP; Yu, HY | 1 |
Attin, T; Wiegand, A | 1 |
de Alencar, CR; de Andrade Moreira Machado, MA; de Oliveira, TM; Honório, HM; Magalhães, AC; Rios, D | 1 |
Cheaib, Z; Eick, S; Lussi, A; Rakmathulina, E | 1 |
Ccahuana-Vásquez, RA; de Oliveira Diniz, LV; de Oliveira, AF; Forte, FD; Sampaio, FC; Tochukwu Amaechi, B | 1 |
Alencar, CR; Buzalaf, MA; Honório, HM; Jordão, MC; Machado, MA; Magalhães, AC; Mesquita, IM; Rios, D | 1 |
Hannig, C; Hannig, M; Hoth-Hannig, W; Kensche, A; Pötschke, S; Richter, G | 1 |
Addy, M; Allen, GC; Barbour, ME; Parker, DM; Shellis, RP | 1 |
Bartlett, DW; Kaidonis, JA; Ranjitkar, S; Richards, LC; Rodriguez, JM; Townsend, GC | 1 |
Lussi, A; Neuhaus, KW | 1 |
Panich, M; Poolthong, S | 1 |
Gleissner, C; Schulz-Dobrick, B; Willershausen, B | 1 |
Kaidonis, JA; Ranjitkar, S; Richards, LC; Townsend, GC | 1 |
Baca, P; Forner, L; Llena, C | 1 |
Bianchi, S; Chiesa, M; Dagna, A; Lombardini, M; Poggio, C | 1 |
Lussi, A | 1 |
Meyers, IA | 2 |
Kavitha, M; Loganathan, SC; Srinivasan, N | 1 |
Attin, T; Wegehaupt, FJ | 1 |
Brearley-Messer, LJ; Cai, F; Cochrane, NJ; Manton, DJ; Reynolds, C; Reynolds, EC; Walker, GD; Yuan, Y | 1 |
Addy, M; Barbour, ME; Hemingway, CA; Parker, DM; Shellis, RP; White, AJ | 1 |
Hellwig, E; Lussi, A; Megert, B; Neuhaus, KW; Wang, X | 1 |
Seow, WK; Taji, S | 1 |
Barbour, ME; Gracia, LH; White, AJ | 1 |
Rirattanapong, P; Surarit, R; Vongsawan, K | 1 |
Parolia, A | 1 |
Cheaib, Z; Lussi, A | 1 |
Attin, T; Schmidlin, PR; Stillhard, A; Tauböck, TT; Wegehaupt, FJ | 1 |
Gupta, R; Prakash, V | 1 |
Galafassi, D; Maeda, FA; Messias, DC; Neto, FC; Serra, MC; Turssi, CP | 1 |
Watanabe, K; Watanabe, S; Wen, LY; Xuan, K; Zhou, J; Zhou, SL | 1 |
Fitzgerald, RJ; Nongonierma, AB | 1 |
Chang, CH; Cochrane, NJ; Reynolds, C; Reynolds, EC; Shen, P; Walker, GD; Yuan, Y | 1 |
Bronkhorst, E; Huysmans, MC; Jager, DH; Timmer, CJ; Vieira, AM; Vissink, A | 1 |
Cantile, T; Coda, M; Ferrazzano, GF; Ingenito, A; Sangianantoni, G | 1 |
Inage, H; Miyazaki, M; Moore, BK; Takamizawa, T; Yamaguchi, K | 1 |
Attin, T; Becker, K; Buchalla, W; Lennon, AM; Lennon, S; Pfeffer, M | 1 |
Chadwick, B; Loyn, T; Rees, J | 1 |
Inage, H; Kurokawa, H; Miyazaki, M; Takamizawa, T; Yamaguchi, K | 1 |
Hunt, D; McIntyre, J; Piekarz, C; Ranjitkar, S | 1 |
6 review(s) available for caseins and Tooth Erosion
Article | Year |
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[Casein phosphopeptide--amorphous calcium phosphate (CPP-ACP) and its effect on dental hard tissues].
Topics: Animals; Cariostatic Agents; Caseins; Dental Caries; Dental Enamel; Dental Restoration, Permanent; Dentin; Dentin Sensitivity; Drug Combinations; Glass Ionomer Cements; Humans; Milk; Milk Proteins; Randomized Controlled Trials as Topic; Tooth Erosion; Tooth Remineralization; Xerostomia | 2009 |
Anticariogenicity of casein phosphopeptide-amorphous calcium phosphate: a review of the literature.
Topics: Biofilms; Calcium; Cariostatic Agents; Caseins; Dental Caries; Dental Enamel; Dental Plaque; Dentin; Humans; Phosphates; Saliva; Tooth Erosion; Tooth Remineralization; Xerostomia | 2009 |
Dental erosion--novel remineralizing agents in prevention or repair.
Topics: Animals; Beverages; Calcium Phosphates; Caseins; Dental Pellicle; Fluorides; Humans; Tooth Erosion; Tooth Remineralization | 2009 |
A literature review of dental erosion in children.
Topics: Ascorbic Acid; Australia; Beverages; Caseins; Child; Child, Preschool; Dental Caries; Dental Enamel Hypoplasia; Dental Pellicle; Drug-Related Side Effects and Adverse Reactions; Feeding and Eating Disorders; Fluorides, Topical; Gastroesophageal Reflux; Germany; Humans; Prevalence; Risk Factors; Tooth Erosion; Tooth, Deciduous; United Kingdom; Vomiting | 2010 |
CPP-ACP complex as a new adjunctive agent for remineralisation: a review.
Topics: Administration, Topical; Bacterial Adhesion; Calcium Phosphates; Cariostatic Agents; Caseins; Chewing Gum; Dose-Response Relationship, Drug; Drug Interactions; Fluorides; Humans; Mouthwashes; Tooth Demineralization; Tooth Erosion; Tooth Remineralization | 2011 |
Biofunctional properties of caseinophosphopeptides in the oral cavity.
Topics: Animals; Calcium Phosphates; Caseins; Dental Caries; Dentin Sensitivity; Drug Synergism; Fluorides; Humans; Phosphopeptides; Tooth Erosion; Tooth Remineralization | 2012 |
10 trial(s) available for caseins and Tooth Erosion
Article | Year |
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In situ effect of Tooth Mousse containing CPP-ACP on human enamel subjected to in vivo acid attacks.
Topics: Acids; Carbonated Beverages; Caseins; Cross-Over Studies; Dental Enamel; Humans; Tooth Erosion; Tooth Remineralization | 2018 |
In situ effect of chewing gum containing CPP-ACP on the mineral precipitation of eroded bovine enamel-a surface hardness analysis.
Topics: Adult; Animals; Caseins; Cattle; Chemical Precipitation; Chewing Gum; Citric Acid; Cross-Over Studies; Dental Enamel; Female; Hardness; Humans; Male; Minerals; Prospective Studies; Single-Blind Method; Tooth Erosion; Tooth Remineralization; Young Adult | 2013 |
Randomised in situ trial on the effect of milk and CPP-ACP on dental erosion.
Topics: Adult; Amines; Animals; Cariostatic Agents; Caseins; Cattle; Cross-Over Studies; Dental Enamel; Dentin; Female; Fluorides; Humans; Male; Milk; Mouthwashes; Prospective Studies; Single-Blind Method; Sodium Fluoride; Tin Compounds; Tooth Abrasion; Tooth Erosion; Toothpastes | 2014 |
In situ effect of a commercial CPP-ACP chewing gum on the human enamel initial erosion.
Topics: Adult; Carbonated Beverages; Caseins; Chewing Gum; Cross-Over Studies; Dental Enamel; Female; Follow-Up Studies; Hardness; Humans; Hydrogen-Ion Concentration; Male; Saliva; Secretory Rate; Single-Blind Method; Tooth Erosion; Tooth Remineralization; Young Adult | 2014 |
In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion.
Topics: Adult; Caseins; Chewing Gum; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Surface Properties; Tooth Abrasion; Tooth Erosion; Treatment Outcome | 2017 |
In situ Effect of Chewing Gum with and without CPP-ACP on Enamel Surface Hardness Subsequent to ex vivo Acid Challenge.
Topics: Adolescent; Adult; Analysis of Variance; Carbonated Beverages; Caseins; Chewing Gum; Cross-Over Studies; Dental Enamel; Female; Hardness; Humans; Male; Saliva; Single-Blind Method; Time Factors; Tooth Demineralization; Tooth Erosion; Young Adult | 2016 |
Protective effect on enamel demineralization of a CPP-ACP paste: an AFM in vitro study.
Topics: Carbonated Beverages; Caseins; Dental Enamel; Humans; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Materials Testing; Microscopy, Atomic Force; Protective Agents; Temperature; Time Factors; Tooth Demineralization; Tooth Erosion; Tooth Remineralization | 2009 |
Comparison of the remineralization potential of CPP-ACP and CPP-ACP with 900 ppm fluoride on eroded human enamel: An in situ study.
Topics: Adult; Carbonated Beverages; Cariostatic Agents; Caseins; Dental Enamel; Drug Synergism; Equipment Design; Female; Fluorides; Hardness; Humans; Male; Saliva; Stress, Mechanical; Tooth Demineralization; Tooth Erosion; Tooth Remineralization; Young Adult | 2010 |
Influence of extra- and intra-oral application of CPP-ACP and fluoride on re-hardening of eroded enamel.
Topics: Administration, Topical; Adult; Amines; Analysis of Variance; Animals; Cariostatic Agents; Caseins; Cattle; Dental Enamel; Drug Combinations; Drug Therapy, Combination; Female; Hardness; Humans; Male; Reference Values; Tin Fluorides; Tooth Demineralization; Tooth Erosion; Tooth Remineralization; Tooth, Artificial; Young Adult | 2012 |
Reduction of erosion by protein-containing toothpastes.
Topics: Calcium; Caseins; Citric Acid; Cross-Over Studies; Dental Enamel; Dental Pellicle; Disease Progression; Double-Blind Method; Glucan 1,4-alpha-Glucosidase; Glucose Oxidase; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Lactoferrin; Lactoperoxidase; Muramidase; Phosphates; Placebos; Proteins; Tooth Erosion; Toothpastes; Water | 2013 |
35 other study(ies) available for caseins and Tooth Erosion
Article | Year |
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Remineralizing Effect of Casein Phosphopeptide-Amorphous Calcium Phosphate and Sodium Fluoride on Artificial Tooth Enamel Erosion: An
Topics: Calcium Phosphates; Caseins; Dental Enamel; Humans; Phosphopeptides; Sodium Fluoride; Tooth Erosion; Tooth Remineralization; Tooth, Artificial | 2019 |
The use of a new calcium mesoporous silica nanoparticle versus calcium and/or fluoride products in reducing the progression of dental erosion.
Topics: Calcium; Caseins; Fluorides; Humans; Nanoparticles; Silicon Dioxide; Sodium Fluoride; Tooth Erosion; Tooth Remineralization | 2020 |
Pellicle Modification with Casein and Mucin Does Not Affect Surface Loss from Erosion and Abrasion.
Topics: Caseins; Dental Enamel; Dental Pellicle; Humans; Mucins; Tooth Abrasion; Tooth Erosion | 2020 |
Efficacy of different strategies to treat root dentin eroded by liquid or gaseous hydrochloric acid associated with brushing abrasion.
Topics: Caseins; Dentin; Gases; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Lasers, Solid-State; Microscopy, Confocal; Random Allocation; Surface Properties; Tooth Abrasion; Tooth Erosion; Tooth Root; Toothbrushing | 2018 |
Effects of citric acid modified with fluoride, nano-hydroxyapatite and casein on eroded enamel.
Topics: Animals; Caseins; Cattle; Citric Acid; Durapatite; In Vitro Techniques; Incisor; Materials Testing; Sodium Fluoride; Surface Properties; Tooth Erosion; Tooth Remineralization | 2018 |
[Effects of casein phosphopeptide-amorphic calcium phosphate on enamel erosion: an
Topics: Carbonated Beverages; Caseins; Dental Enamel; Humans; Random Allocation; Tooth Erosion; Tooth Remineralization | 2018 |
Acquired Enamel Pellicle Modification with Casein and Mucin in Different Concentrations and its Impact on Initial Dental Erosion.
Topics: Caseins; Citric Acid; Dental Enamel; Dental Pellicle; Humans; In Vitro Techniques; Mucins; Random Allocation; Tooth Erosion | 2019 |
Interplay between experimental dental pellicles and stannous-containing toothpaste on dental erosion-abrasion.
Topics: Analysis of Variance; Animals; Caseins; Dental Enamel; Dental Pellicle; Dentin; Humans; Milk; Mucins; Salivary Proteins and Peptides; Serum Albumin, Bovine; Sodium Fluoride; Tin Compounds; Tooth Abrasion; Tooth Erosion; Tooth Remineralization; Tooth Root; Toothpastes | 2013 |
The CPP-ACP relieved enamel erosion from a carbonated soft beverage: an in vitro AFM and XRD study.
Topics: Animals; Carbonated Beverages; Caseins; Cattle; Cola; Dental Enamel; Hardness; In Vitro Techniques; Microscopy, Atomic Force; Saliva, Artificial; Surface Properties; Tooth Erosion; Tooth Remineralization; X-Ray Diffraction | 2014 |
Impact of Acquired Pellicle Modification on Adhesion of Early Colonizers.
Topics: Bacterial Adhesion; Caseins; Dental Enamel; Dental Enamel Solubility; Dental Pellicle; Humans; Saliva; Tooth Erosion | 2015 |
Influence of Calcium Phosphate and Apatite Containing Products on Enamel Erosion.
Topics: Animals; Biomimetic Materials; Calcium Phosphates; Caseins; Cattle; Dental Enamel; Durapatite; Fluorides; In Vitro Techniques; Mouthwashes; Tooth Erosion | 2016 |
Inhibition of hydroxyapatite dissolution by whole casein: the effects of pH, protein concentration, calcium, and ionic strength.
Topics: Calcium; Caseins; Citric Acid; Dental Enamel Solubility; Dental Pellicle; Dose-Response Relationship, Drug; Durapatite; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Protein Binding; Tooth Erosion | 2008 |
The effect of casein phosphopeptide-amorphous calcium phosphate on erosive enamel and dentine wear by toothbrush abrasion.
Topics: Calcium Phosphates; Caseins; Dental Enamel; Dentifrices; Dentin; Humans; Models, Statistical; Molar, Third; Phosphopeptides; Tooth Abrasion; Tooth Erosion; Tooth Remineralization; Toothbrushing | 2009 |
The effect of casein phosphopeptide-amorphous calcium phosphate and a cola soft drink on in vitro enamel hardness.
Topics: Analysis of Variance; Carbonated Beverages; Cariostatic Agents; Caseins; Cola; Dental Enamel; Hardness; Humans; Saliva, Artificial; Tooth Erosion; Tooth Remineralization | 2009 |
In vitro evaluation of enamel remineralisation by a casein phosphopeptide-amorphous calcium phosphate paste.
Topics: Adult; Beverages; Calcium; Cariostatic Agents; Caseins; Dental Enamel; Electron Probe Microanalysis; Humans; Materials Testing; Microscopy, Electron, Scanning; Middle Aged; Minerals; Phosphorus; Time Factors; Tooth Demineralization; Tooth Erosion; Tooth Remineralization; Toothpastes | 2009 |
The effect of CPP-ACP on enamel wear under severe erosive conditions.
Topics: Cariostatic Agents; Caseins; Dental Enamel; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Materials Testing; Time Factors; Tooth Attrition; Tooth Erosion | 2009 |
Diagnosis and management of the worn dentition: risk management and pre-restorative strategies for the oral and dental environment.
Topics: Adult; Age Factors; Aged; Buffers; Carbonated Beverages; Cariostatic Agents; Caseins; Dental Restoration, Permanent; Feeding Behavior; Fluorides; Humans; Life Style; Middle Aged; Oral Hygiene; Patient Compliance; Risk Assessment; Saliva; Tooth Abrasion; Tooth Attrition; Tooth Demineralization; Tooth Erosion; Tooth Remineralization; Treatment Outcome | 2008 |
Diagnosis and management of the worn dentition: conservative restorative options.
Topics: Acid Etching, Dental; Cariostatic Agents; Caseins; Composite Resins; Crowns; Dental Bonding; Dental Materials; Dental Prosthesis Design; Dental Restoration, Permanent; Fluorides; Follow-Up Studies; Humans; Male; Middle Aged; Oral Hygiene; Patient Care Planning; Polyvinyls; Siloxanes; Surface Properties; Tooth Abrasion; Tooth Attrition; Tooth Erosion; Tooth Preparation; Toothpastes; Vertical Dimension | 2008 |
The role of fluoride and casein phosphopeptide/amorphous calcium phosphate in the prevention of erosive/abrasive wear in an in vitro model using hydrochloric acid.
Topics: Acids; Administration, Topical; Animals; Calcium Phosphates; Cariostatic Agents; Caseins; Cattle; Dental Enamel; Fluorides, Topical; Tooth Erosion; Tooth Wear; Toothbrushing | 2010 |
Effect of casein phosphopeptide-amorphous calcium phosphate added to acidic beverages on enamel erosion in vitro.
Topics: Beverages; Carbonated Beverages; Cariostatic Agents; Caseins; Chelating Agents; Citrus; Dental Enamel; Dietary Sucrose; Flavoring Agents; Fruit; Humans; Hydrogen-Ion Concentration; Materials Testing; Temperature; Time Factors; Tooth Erosion; Water | 2010 |
Enamel erosion in dietary acids: inhibition by food proteins in vitro.
Topics: Acids; Administration, Topical; Animals; Beverages; Caseins; Dental Enamel; Dental Enamel Solubility; Dental Pellicle; Dietary Supplements; Humans; Hydrogen-Ion Concentration; Ovalbumin; Polymers; Tooth Erosion | 2010 |
Preventing erosion with novel agents.
Topics: Beverages; Caseins; Citrus; Dental Enamel; Dental Pellicle; Fluorides; Fruit; Glass; Hardness; Humans; Hydrogen-Ion Concentration; Materials Testing; Microscopy, Electron, Scanning; Pharmaceutical Preparations, Dental; Saliva, Artificial; Temperature; Time Factors; Tooth Erosion; Tooth Remineralization | 2011 |
Inhibition of dental erosion by casein and casein-derived proteins.
Topics: Animals; Caseins; Cattle; Dental Enamel; Hardness; Peptide Fragments; Phosphopeptides; Sodium Fluoride; Tooth Erosion | 2011 |
The effect of high calcium milk and casein phosphopeptide-amorphous calcium phosphate on enamel erosion caused by cholinated water.
Topics: Animals; Calcium; Cariostatic Agents; Caseins; Cattle; Chlorine; Dental Enamel; In Vitro Techniques; Milk; Tooth Erosion; Water Supply | 2010 |
Soft drink erosion and Cpp-Acp.
Topics: Beverages; Carbonated Beverages; Caseins; Chelating Agents; Dental Enamel; Humans; Hydrogen-Ion Concentration; Tooth Erosion; Tooth Remineralization | 2011 |
Impact of acquired enamel pellicle modification on initial dental erosion.
Topics: Adult; Analysis of Variance; Bicuspid; Caseins; Dental Enamel; Dental Pellicle; Drug Combinations; Female; Hardness; Humans; Male; Middle Aged; Mucins; Salivary Proteins and Peptides; Statistics, Nonparametric; Tooth Erosion | 2011 |
Effect of potential remineralizing agents on acid softened enamel.
Topics: Animals; Cariostatic Agents; Caseins; Cattle; Citric Acid; Dental Enamel; Dentifrices; Drug Combinations; Fluorides; Glass; Hardness; Hydrogen-Ion Concentration; Materials Testing; Microscopy, Atomic Force; Nitrates; Phosphates; Random Allocation; Saliva, Artificial; Sodium Fluoride; Tooth Erosion; Tooth Remineralization | 2011 |
In vitro study of the effects of fluoride-releasing dental materials on remineralization in an enamel erosion model.
Topics: Animals; Cariostatic Agents; Caseins; Cattle; Composite Resins; Dental Enamel; Dental Materials; Disease Models, Animal; Fluorescence; Fluorides; Fluorides, Topical; Glass Ionomer Cements; Hardness; Imaging, Three-Dimensional; Materials Testing; Microscopy, Electron, Scanning; Pit and Fissure Sealants; Sodium Fluoride; Time Factors; Tooth Erosion; Tooth Remineralization | 2012 |
Erosive potential of sports beverages.
Topics: Acids; Analysis of Variance; Apatites; Australia; Beverages; Calcium; Caseins; Dental Enamel; Dental Enamel Solubility; Humans; Hydrogen-Ion Concentration; Sports; Taste; Tooth Erosion | 2012 |
SEM investigation on casein phosphopeptides capability in contrasting cola drinks enamel erosion: an in vitro preliminary study.
Topics: Adolescent; Carbonated Beverages; Cariostatic Agents; Caseins; Child; Dental Enamel; Dental Enamel Solubility; Humans; Hydrogen-Ion Concentration; Materials Testing; Microscopy, Electron, Scanning; Time Factors; Tooth Erosion | 2012 |
Effect of CPP-ACP paste on mechanical properties of bovine enamel as determined by an ultrasonic device.
Topics: Animals; Caseins; Cattle; Dental Enamel; Tooth Demineralization; Tooth Erosion; Toothpastes; Ultrasonics | 2006 |
Effect of a casein/calcium phosphate-containing tooth cream and fluoride on enamel erosion in vitro.
Topics: Amines; Animals; Ascorbic Acid; Calcium Phosphates; Caseins; Cattle; Dental Enamel; Dental Enamel Solubility; Dentifrices; Diamines; Dose-Response Relationship, Drug; Drug Combinations; Fluorides; Fluorides, Topical; Hydrogen-Ion Concentration; Sodium Fluoride; Statistics, Nonparametric; Tin Fluorides; Tooth Erosion | 2006 |
Pronamel and tooth mousse: an initial assessment of erosion prevention in vitro.
Topics: Analysis of Variance; Caseins; Dental Enamel; Dentifrices; Drug Combinations; Fluorides; Humans; Nitrates; Potassium Compounds; Tooth Erosion; Tooth Remineralization | 2007 |
Ultrasonic determination of the effect of casein phosphopeptide-amorphous calcium phosphate paste on the demineralization of bovine dentin.
Topics: Analysis of Variance; Animals; Cariostatic Agents; Caseins; Cattle; Dentin; Microscopy, Electron, Scanning; Statistics, Nonparametric; Tooth Demineralization; Tooth Erosion; Ultrasonography | 2007 |
An in vitro assessment of the role of Tooth Mousse in preventing wine erosion.
Topics: Cariostatic Agents; Caseins; Dental Cementum; Dental Enamel; Dentin; Humans; Hydrogen-Ion Concentration; Materials Testing; Saliva, Artificial; Tooth Erosion; Tooth Remineralization; Wine | 2008 |