Page last updated: 2024-09-04

caseins and Autoimmune Diabetes

caseins has been researched along with Autoimmune Diabetes in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (24.36)	18.2507
2000's	36 (46.15)	29.6817
2010's	18 (23.08)	24.3611
2020's	5 (6.41)	2.80

Authors

Authors	Studies
Cuthbertson, D; Erlund, I; Honkanen, J; Hyöty, H; Knip, M; Krischer, JP; Miettinen, ME; Niinistö, S; Nucci, AM; Vaarala, O; Virtanen, SM	1
Couluris, M; Cuthbertson, D; Knip, M; Krischer, JP; Virtanen, SM	1
Couluris, M; Cuthbertson, D; Knip, M; Krischer, JP; Savilahti, E; Virtanen, SM	1
Ahonen, S; Honkanen, J; Ilonen, J; Jason, E; Knip, M; Koivusaari, K; Lähdeaho, ML; Ruohtula, T; Salonen, M; Selvenius, J; Siljander, H; Vaarala, O; Virtanen, SM	1
Bao, X; Qian, K; Yao, P	1
Chia, JSJ; Dwyer, KM; Elliott, RB; Kukuljan, S; McRae, JL; Swinburn, B; Woodford, K	1
Åkerblom, HK; Härkönen, T; Hyytinen, M; Ilonen, J; Knip, M; Luopajärvi, K; Savilahti, E; Uibo, R; Vaarala, O; Virtanen, SM	1
Åkerblom, HK; Al Taji, E; Becker, D; Bruining, J; Castano, L; Danne, T; de Beaufort, C; Dosch, HM; Dupre, J; Fraser, WD; Howard, N; Ilonen, J; Knip, M; Konrad, D; Kordonouri, O; Krischer, JP; Lawson, ML; Ludvigsson, J; Madacsy, L; Mahon, JL; Ormisson, A; Palmer, JP; Pozzilli, P; Savilahti, E; Serrano-Rios, M; Songini, M; Taback, S; Vaarala, O; Virtanen, SM; Wasikowa, R; White, NH	1
Chia, JSJ; Dwyer, KM; Enjapoori, AK; Kukuljan, S; Lefèvre, CM; McRae, JL	1
Åkerblom, HK; Becker, D; Dosch, HM; Dupre, J; Fraser, W; Howard, N; Ilonen, J; Knip, M; Kordonouri, O; Krischer, JP; Lawson, ML; Palmer, JP; Savilahti, E; Vaarala, O; Virtanen, SM	1
Overbeck, P	1
Crookshank, JA; Noel, JA; Patrick, C; Scott, FW; Wang, GS	1
Merriman, TR	1
Bos, NA; Hillebrands, JL; Rozing, J; Visser, J; Walther Boer, M	1
Boirie, Y; Crombach, N; Fauquant, J; Gijsen, AP; Kies, AK; Koopman, R; Lemosquet, S; Saris, WH; van Loon, LJ; Walrand, S	1
Bonifacio, E; Koczwara, K; Mueller, AS; Mueller, DB; Pallauf, J; Ziegler, AG	1
Beijer-Liefers, S; Boer, MW; Bos, NA; Brugman, S; Fasano, A; Harmsen, H; Hoogendijk, A; Lammers, K; Rozing, J; Stellaard, F; Visser, JT; Welling, G; Zandvoort, A	1
Akerblom, HK; Dosch, HM; Hakulinen, T; Hämäläinen, AM; Ilonen, J; Knip, M; Paronen, J; Reunanen, A; Savilahti, E; Seppä, K; Teramo, K; Vaarala, O; Virtanen, SM	1
Harlan, DM; Lee, MM	1
Åkerblom, HK; Bärlund, S; Einberg, Ü; Erkkola, M; Hämäläinen, AM; Ilonen, J; Knip, M; Ludvigsson, JG; Ormisson, A; Paronen, J; Reunanen, A; Riikjärv, MA; Salonen, M; Savilahti, E; Teramo, K; Virtanen, SM	1
Akerblom, HK; Becker, D; Berseth, C; Bradley, B; Dupré, J; Fransiscus, M; Ilonen, J; Knip, M; Koski, K; Koski, M; Krischer, J; Lough, G; Pajakkala, E; Savilahti, E; Trucco, M; Virtanen, SM	1
Clemens, RA	1
Achenbach, P; Adler, K; Bonifacio, E; Heninger, AK; Krause, S; Mueller, DB; Ziegler, AG	1
Chae, YK; Kim, J	1
Allen, KJ; Vuillermin, P	1
Vaarala, O	1
Beijer-Liefers, S; Bos, NA; Harthoorn, LF; Rozing, J; Stellaard, F; van Tol, EA; Visser, JT	1
Chakrabarty, S; Chowdhury, SA; Jin, Z; Kotani, R; Moriyama, H; Nagata, M; Nakayama, M; Yamada, K; Yasuda, H; Yokono, K	1
Baroni, MG; Bianchi, M; Cavallo, MG; Di Giulio, C; Di Tola, M; La Presa, M; Manfrini, S; Monetini, L; Petrone, A; Picarelli, A; Pozzilli, P; Stefanini, L; Thorpe, R; Walker, BK	1
Beales, PE; Elliott, RB; Flohé, S; Hill, JP; Kolb, H; Pozzilli, P; Scott, FW; Wang, GS; Wasmuth, H	1
Birgisdottir, BE; Harris, DP; Hill, JP; Thorsdottir, I	1
Barone, F; Cavallo, MG; Jung, G; Monetini, L; Petrone, A; Pozzilli, P; Stefanini, L; Thorpe, R; Walk, T	1
Hill, JP	1
Beaglehole, R; Jackson, R	1
Elliott, R; Laugesen, M	2
Brugman, S; Groen, H; Klatter, F; Rozing, J; Strubbe, J; Vis, L; Visser, J	1
Kolb, H; Scott, FW	1
McLachlan, C; Olsson, F	1
Akerblom, HK; Hämäläinen, AM; Hyöty, H; Ilonen, J; Knip, M; Koskela, P; Lönnrot, M; Sadeharju, K; Virtanen, SM	1
Marchesini, M; Perrin, IV; Rochat, FC; Schiffrin, EJ; Schilter, B	1
Manfrini, S; Picardi, A; Pozzilli, P	1
Benderly, A; Etzioni, A; Shamir, R; Shehadeh, N; Teninboum, G; Weis, R	1
Djalali, M; Eshraghian, MR; Keshavarz, A; Neyestani, TR; Pezeshki, M; Rajab, A; Siassi, F	1
Truswell, AS	1
Allison, AJ; Clarke, AJ	1
Bell, SJ; Clarke, AJ; Grochoski, GT	1
Birgisdottir, BE; Hill, JP; Thorsdottir, I; Thorsson, AV	1
Bos, NA; Brugman, S; Harmsen, HJ; Klatter, FA; Rozing, J; Visser, JT; Wildeboer-Veloo, AC	1
Bazzigaluppi, E; Bottazzo, G; Buzzetti, R; Cherubini, V; Falorni, A; Lorini, R; Minicucci, L; Napoli, F; Padovani, P; Pozzilli, P; Tortoioli, C	1
Cieslińska, A; Kamiński, S; Kostyra, E	1
Buschard, K; Damsbo, P; Josefsen, K; Lorentzen, S; Nielsen, H	1
Buschard, K; Dagnaes-Hansen, F; Hoorfar, J	1
Atlan-Gepner, C; Hermitte, L; Mehelleb, M; Payan, MJ; Vialettes, B	1
Akerblom, HK; Ilonen, J; Klemetti, P; Reijonen, H; Savilahti, E; Vaarala, O	1
Barrow, G; Bibby, NJ; Elliott, RB; Reddy, S; Swinney, C; Wu, D	1
Li, XB; Park, YH; Scott, FW; Yoon, JW	1
Harrison, LC	1
Barone, F; Cavallo, MG; Fava, D; Monetini, L; Pozzilli, P	1
Gray, DW	1
Bottazzo, GF; Elliot, RB; Hill, J; Songini, M; Wasmuth, H	1
Cheung, RK; Dosch, HM; Hammond-McKibben, D; Karges, W; Kemp, D; Shibuya, N; Visconti, M	1
Greiner, DL; Hansen, JW; Malkani, S; Mordes, JP; Nompleggi, D; Rossini, AA	1
Atkinson, MA; Ellis, TM; Jodoin, E; Ottendorfer, E; Salisbury, PJ; Schatz, DA; She, JX	1
Field, CJ; Glen, S; McBurney, MI; Reimer, RA	1
Bibby, NJ; Elliott, RB; Harris, DP; Hill, JP; Wasmuth, HE	1
Bonifacio, E; Dozio, N; Meschi, F; Pastore, MR; Sarugeri, E	1
Ladrière, L; Laghmich, A; Malaisse, WJ; Olivares, E; Scott, FW; Sener, A	2
Becker, F; Federlin, K; Padberg, S; Petzoldt, R; Schumm-Draeger, PM	1
Jagla, A; Schrezenmeir, J	1
Birgisdottir, BE; Harris, DP; Hill, J; Johannsdottir, IM; Steingrimsdottir, L; Thorsdottir, I; Thorsson, AV	1
Akerblom, HK; Ilonen, J; Knip, M; Paronen, J; Savilahti, E; Vaarala, O; Virtanen, SM	1
Astsaturov, I; Becker, DJ; Cheung, RK; Dosch, HM; Gunaratnam, L; McKerlie, C; Moscarello, MA; O'Connor, P; Schrade, K; Winer, S; Wood, DD	1
Bizzarri, C; Cavallo, MG; Cervoni, M; Coppolino, G; Corbi, S; Crinò, A; Ferrazzoli, F; Mesturino, CA; Monetini, L; Pozzilli, P	1
Burghardt, K; Flohé, S; Kolb, H; Rowsell, P; Scott, FW; Wang, GS	1
Banchuin, N; Boonyasrisawat, W; Deerochanawong, C; Dharakul, T; Pasurakul, T; Ploybutr, S; Sriussadaporn, S; Vannasaeng, S; Yenchitsomanus, PT	1
Brogren, CH; Buschard, K; Hoorfar, J	1

Reviews

8 review(s) available for caseins and Autoimmune Diabetes

Article	Year
A1 beta-casein milk protein and other environmental pre-disposing factors for type 1 diabetes. Nutrition & diabetes, 2017, May-15, Volume: 7, Issue:5 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Humans; Milk; Risk Factors	2017
Type 1 diabetes, the A1 milk hypothesis and vitamin D deficiency. Diabetes research and clinical practice, 2009, Volume: 83, Issue:2 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Ecology; Geography; Humans; Milk; Protein Isoforms; Vitamin D Deficiency	2009
Milk A1 and A2 peptides and diabetes. Nestle Nutrition workshop series. Paediatric programme, 2011, Volume: 67 Topics: Animals; Caseins; Cattle; Diabetes Mellitus, Type 1; Genetic Variation; Humans; Milk; Peptide Fragments	2011
The gut as a regulator of early inflammation in type 1 diabetes. Current opinion in endocrinology, diabetes, and obesity, 2011, Volume: 18, Issue:4 Topics: Animals; Autoimmunity; Caseins; Diabetes Mellitus, Type 1; Humans; Inflammation; Insulin-Secreting Cells; Intestinal Mucosa; Intestines	2011
The A2 milk case: a critical review. European journal of clinical nutrition, 2005, Volume: 59, Issue:5 Topics: Animals; Caseins; Causality; Coronary Disease; Diabetes Mellitus, Type 1; Endorphins; Humans; Milk; Peptide Fragments; Rats	2005
Health implications of milk containing beta-casein with the A2 genetic variant. Critical reviews in food science and nutrition, 2006, Volume: 46, Issue:1 Topics: Adult; Animals; Cardiovascular Diseases; Caseins; Cattle; Diabetes Mellitus, Type 1; Genetic Variation; Humans; Infant; Milk; Rabbits; Rats; Risk Factors	2006
Polymorphism of bovine beta-casein and its potential effect on human health. Journal of applied genetics, 2007, Volume: 48, Issue:3 Topics: Animals; Caseins; Cattle; Diabetes Mellitus, Type 1; Genetic Variation; Humans; Milk; Myocardial Ischemia; Polymorphism, Genetic	2007
Milk and diabetes. Journal of the American College of Nutrition, 2000, Volume: 19, Issue:2 Suppl Topics: Animals; Antigens; Caseins; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Insulin; Lactoglobulins; Milk	2000

Trials

14 trial(s) available for caseins and Autoimmune Diabetes

Article	Year
Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study. Diabetologia, 2020, Volume: 63, Issue:4 Topics: Age of Onset; Autoantibodies; Autoimmunity; Case-Control Studies; Caseins; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Genetic Predisposition to Disease; Histocompatibility Testing; Humans; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Islets of Langerhans; Male; Nutritional Status; Risk Factors; Vitamin D	2020
Effect of extensively hydrolyzed casein vs. conventional formula on the risk of asthma and allergies: The TRIGR randomized clinical trial. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2021, Volume: 32, Issue:4 Topics: Animals; Asthma; Caseins; Cattle; Child; Diabetes Mellitus, Type 1; Female; Humans; Infant; Infant Formula; Milk Hypersensitivity; Milk Proteins; Rhinitis, Allergic	2021
Effect of Early Feeding on Intestinal Permeability and Inflammation Markers in Infants with Genetic Susceptibility to Type 1 Diabetes: A Randomized Clinical Trial. The Journal of pediatrics, 2021, Volume: 238 Topics: beta-Defensins; Biomarkers; Caseins; Diabetes Mellitus, Type 1; Feeding Behavior; Female; Genetic Predisposition to Disease; Humans; Infant; Infant Formula; Infant, Newborn; Inflammation; Intestinal Absorption; Lactulose; Leukocyte L1 Antigen Complex; Male; Mannitol	2021
Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial. Gastroenterology, 2017, Volume: 153, Issue:4 Topics: Autoantibodies; Autoimmunity; Biopsy; Caseins; Celiac Disease; Child; Child, Preschool; Diabetes Mellitus, Type 1; Double-Blind Method; Duodenum; Finland; Gliadin; GTP-Binding Proteins; Humans; Infant; Infant Formula; Milk Hypersensitivity; Milk Proteins; Protein Glutamine gamma Glutamyltransferase 2; Risk Assessment; Risk Factors; Serologic Tests; Time Factors; Transglutaminases; Treatment Outcome	2017
Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial. JAMA, 2018, 01-02, Volume: 319, Issue:1 Topics: Caseins; Child; Diabetes Mellitus, Type 1; Disease-Free Survival; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant Formula; Infant Nutritional Physiological Phenomena; Infant, Newborn; Male; Nutrition Policy; Risk	2018
Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial. JAMA, 2014, Jun-11, Volume: 311, Issue:22 Topics: Animals; Autoantibodies; Autoimmunity; Breast Feeding; Caseins; Child; Diabetes Mellitus, Type 1; Dietary Proteins; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydrolysis; Incidence; Infant Formula; Infant, Newborn; Insulin-Secreting Cells; Male; Milk; Risk; Weaning	2014
Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein. The American journal of clinical nutrition, 2009, Volume: 90, Issue:1 Topics: Blood Glucose; Carbon Isotopes; Caseins; Cross-Over Studies; Diabetes Mellitus, Type 1; Dietary Proteins; Digestion; Glucose Tolerance Test; Humans; Insulin; Intestinal Absorption; Kinetics; Leucine; Male; Middle Aged; Muscle, Skeletal; Phenylalanine; Protein Hydrolysates	2009
Dietary intervention in infancy and later signs of beta-cell autoimmunity. The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20 Topics: Animals; Autoantibodies; Autoimmunity; Biomarkers; Caseins; Child; Diabetes Mellitus, Type 1; Disease Progression; Double-Blind Method; Genetic Predisposition to Disease; Histocompatibility Testing; Humans; Infant; Infant Formula; Infant, Newborn; Insulin-Secreting Cells; Milk; Milk, Human; Pilot Projects	2010
Feasibility and compliance in a nutritional primary prevention trial in infants at increased risk for type 1 diabetes. Acta paediatrica (Oslo, Norway : 1992), 2011, Volume: 100, Issue:4 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Feasibility Studies; Genetic Predisposition to Disease; Humans; Immunoglobulin A; Immunoglobulin G; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Milk; Patient Compliance; Pilot Projects; Primary Prevention	2011
The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up. Diabetologia, 2011, Volume: 54, Issue:3 Topics: Animals; Breast Feeding; Caseins; Diabetes Mellitus, Type 1; Humans; Infant Formula; Infant, Newborn; Milk; Research Design	2011
Antibodies to bovine beta-casein in diabetes and other autoimmune diseases. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2002, Volume: 34, Issue:8 Topics: Adolescent; Adult; Animals; Antibodies; Autoimmune Diseases; Caseins; Cattle; Celiac Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Histocompatibility Testing; Humans; Immunoglobulin G; Male; Middle Aged; Multiple Sclerosis; Thyroiditis, Autoimmune	2002
Enterovirus infections as a risk factor for type I diabetes: virus analyses in a dietary intervention trial. Clinical and experimental immunology, 2003, Volume: 132, Issue:2 Topics: Antibodies, Viral; Area Under Curve; B-Lymphocytes; Case-Control Studies; Caseins; Diabetes Mellitus, Type 1; Enterovirus Infections; Female; Fetal Blood; Follow-Up Studies; Genetic Predisposition to Disease; HLA-DQ Antigens; HLA-DQ beta-Chains; Humans; Immunoglobulin G; Infant; Infant Food; Infant, Newborn; Logistic Models; Male; Odds Ratio; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Protein Hydrolysates; Risk Factors; RNA, Viral; Sex Factors	2003
Screening for type 1 diabetes genetic risk in newborns of continental Italy. Primary prevention (Prevefin Italy)--preliminary data. Acta bio-medica : Atenei Parmensis, 2005, Volume: 76 Suppl 3 Topics: Animals; Autoantibodies; Autoantigens; Breast Feeding; Caseins; Cattle; Celiac Disease; Contraindications; Diabetes Mellitus, Type 1; Environmental Exposure; Female; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; HLA-D Antigens; Humans; Incidence; Infant Food; Infant Formula; Infant, Newborn; Islets of Langerhans; Italy; Male; Milk Proteins; Molecular Mimicry; Neonatal Screening; Patient Acceptance of Health Care; Vitamin D; Vitamin D Deficiency	2005
Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group. Diabetes, 2000, Volume: 49, Issue:10 Topics: Animals; Antibody Formation; Autoantibodies; Autoimmunity; Caseins; Cattle; Diabetes Mellitus, Type 1; Diet; Female; Genetic Predisposition to Disease; Humans; Immunity, Cellular; Immunization; Immunoenzyme Techniques; Infant; Infant Food; Insulin; Milk; T-Lymphocytes	2000

Other Studies

56 other study(ies) available for caseins and Autoimmune Diabetes

Article	Year
Association of diabetes-related autoantibodies with the incidence of asthma, eczema and allergic rhinitis in the TRIGR randomised clinical trial. Diabetologia, 2020, Volume: 63, Issue:9 Topics: Animals; Asthma; Autoantibodies; Caseins; Child; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Humans; Incidence; Infant Formula; Insulin Antibodies; Male; Milk; Randomized Controlled Trials as Topic; Rhinitis, Allergic; Zinc Transporter 8	2020
Insulin- and cholic acid-loaded zein/casein-dextran nanoparticles enhance the oral absorption and hypoglycemic effect of insulin. Journal of materials chemistry. B, 2021, 08-21, Volume: 9, Issue:31 Topics: Administration, Oral; Alloxan; Animals; Biological Availability; Caseins; Cholic Acid; Dextrans; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hypoglycemic Agents; Insulin; Male; Materials Testing; Mice; Mice, Inbred ICR; Nanoparticles; Optical Imaging; Zein	2021
Dietary Cows' Milk Protein A1 Beta-Casein Increases the Incidence of T1D in NOD Mice. Nutrients, 2018, Sep-12, Volume: 10, Issue:9 Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Biomarkers; Blood Glucose; Caseins; Cells, Cultured; Coculture Techniques; Diabetes Mellitus, Type 1; Dietary Supplements; Female; Gastrointestinal Microbiome; Gene-Environment Interaction; Genetic Predisposition to Disease; Male; Mice, Inbred NOD; Risk Factors; T-Lymphocytes, Regulatory	2018
[Type 1 diabetes. Cow's milk acquitted]. MMW Fortschritte der Medizin, 2014, Jul-24, Volume: 156, Issue:13 Topics: Animals; Autoantibodies; Caseins; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 1; Genetic Predisposition to Disease; Humans; Infant; Infant Formula; Infant, Newborn; Insulin-Secreting Cells; Milk; Milk Proteins; Risk Factors	2014
Gut immune deficits in LEW.1AR1-iddm rats partially overcome by feeding a diabetes-protective diet. Immunology, 2015, Volume: 145, Issue:3 Topics: Animals; Caseins; Cytokines; Diabetes Mellitus, Type 1; Diet; Diet, Diabetic; Digestive System; Disease Models, Animal; Edible Grain; Flow Cytometry; Gene Expression; Homeostasis; Humans; Immunity; Inflammation Mediators; Interferon-gamma; Jejunum; Macrophages; Rats, Inbred BB; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; T-Lymphocytes, Regulatory; Weaning	2015
Prevention of diabetes by a hydrolysed casein-based diet in diabetes-prone BioBreeding rats does not involve restoration of the defective natural regulatory T cell function. Diabetologia, 2009, Volume: 52, Issue:7 Topics: Animal Feed; Animals; Caseins; Diabetes Mellitus, Type 1; Lymph Nodes; Prediabetic State; Rats; Rats, Inbred BB; Spleen; T-Lymphocytes, Regulatory	2009
Influence of early nutritional components on the development of murine autoimmune diabetes. Annals of nutrition & metabolism, 2009, Volume: 54, Issue:3 Topics: Albumins; Animal Feed; Animals; Body Weight; Caseins; Daucus carota; Diabetes Mellitus, Type 1; Diet; Dietary Proteins; Female; Globulins; Glutens; Glycine max; Glycosuria; Insulin Antibodies; Kaplan-Meier Estimate; Male; Malus; Mice; Mice, Inbred NOD; Poultry Products; Random Allocation; Solanum tuberosum; Soybean Proteins; Statistics, Nonparametric; Triticum; Zea mays	2009
Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat. Diabetologia, 2010, Volume: 53, Issue:12 Topics: Animals; Caseins; Cholera Toxin; Claudins; Cytokines; Diabetes Mellitus, Type 1; Diet; Disease Susceptibility; Electric Impedance; Haptoglobins; Intestinal Absorption; Intestinal Mucosa; Myosins; Permeability; Protein Precursors; Rats; Rats, Mutant Strains	2010
Infant formula, autoimmune triggers, and type 1 diabetes. The New England journal of medicine, 2010, Nov-11, Volume: 363, Issue:20 Topics: Autoantibodies; Autoimmunity; Caseins; Diabetes Mellitus, Type 1; Genetic Predisposition to Disease; Humans; Infant; Infant Formula; Insulin-Secreting Cells	2010
Insulin autoantibodies with high affinity to the bovine milk protein alpha casein. Clinical and experimental immunology, 2011, Volume: 164, Issue:1 Topics: Adolescent; Animals; Autoantibodies; Binding, Competitive; Caseins; Cattle; CD4-Positive T-Lymphocytes; Cell Proliferation; Child; Child, Preschool; Diabetes Mellitus, Type 1; Flow Cytometry; Humans; Infant; Infant Food; Insulin; Insulin Antibodies; Iodine Radioisotopes; Milk Proteins; Protein Binding; Serum Albumin, Bovine	2011
Diet in infancy and later signs of beta-cell autoimmunity. The New England journal of medicine, 2011, 03-03, Volume: 364, Issue:9 Topics: Autoantibodies; Caseins; Diabetes Mellitus, Type 1; Humans; Infant; Infant Formula; Insulin-Secreting Cells	2011
Diet in infancy and later signs of beta-cell autoimmunity. The New England journal of medicine, 2011, 03-03, Volume: 364, Issue:9 Topics: Autoantibodies; Caseins; Child; Diabetes Mellitus, Type 1; Follow-Up Studies; Humans; Infant; Infant Formula; Insulin-Secreting Cells; Intention to Treat Analysis	2011
Potential mechanisms explaining why hydrolyzed casein-based diets outclass single amino acid-based diets in the prevention of autoimmune diabetes in diabetes-prone BB rats. Diabetes/metabolism research and reviews, 2012, Volume: 28, Issue:6 Topics: Amino Acids; Animals; Caseins; Claudin-1; Diabetes Mellitus, Type 1; Diet; Dietary Proteins; Ileum; Intestines; Lactulose; Mannitol; Pancreas; Peptides; Permeability; Rats; Rats, Inbred BB	2012
Detection of GAD65-reactive T-Cells in type 1 diabetes by immunoglobulin-free ELISPOT assays. Diabetes care, 2002, Volume: 25, Issue:8 Topics: Adolescent; Adult; Aged; Autoantibodies; Autoantigens; Caseins; Cell Division; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glutamate Decarboxylase; Humans; Islets of Langerhans; Isoenzymes; Male; Middle Aged; T-Lymphocytes	2002
A multi-centre, blinded international trial of the effect of A(1) and A(2) beta-casein variants on diabetes incidence in two rodent models of spontaneous Type I diabetes. Diabetologia, 2002, Volume: 45, Issue:9 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Diet, Diabetic; Disease Models, Animal; Double-Blind Method; Genetic Variation; Incidence; Mice; Mice, Inbred NOD; Rats; Rats, Inbred BB; Survival	2002
Variation in consumption of cow milk proteins and lower incidence of Type 1 diabetes in Iceland vs the other 4 Nordic countries. Diabetes, nutrition & metabolism, 2002, Volume: 15, Issue:4 Topics: Animals; Caseins; Cattle; Denmark; Diabetes Mellitus, Type 1; Finland; Humans; Iceland; Immunoglobulins; Lactoferrin; Milk Proteins; Norway; Serum Albumin, Bovine; Sweden	2002
Establishment of T cell lines to bovine beta-casein and beta-casein-derived epitopes in patients with type 1 diabetes. The Journal of endocrinology, 2003, Volume: 176, Issue:1 Topics: Adolescent; Animals; Autoantigens; Case-Control Studies; Caseins; Cattle; Cell Culture Techniques; Cell Line; Child; Cross Reactions; Diabetes Mellitus, Type 1; Epitopes; Female; Genotype; Glucose Transporter Type 2; Histocompatibility Testing; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunophenotyping; Insulinoma; Interferon-gamma; Interleukin-4; Islets of Langerhans; Lymphocyte Activation; Male; Monosaccharide Transport Proteins; T-Lymphocytes; Tumor Cells, Cultured	2003
The influence of consumption of A1 beta-casein on heart disease and Type 1 diabetes. The New Zealand medical journal, 2003, Feb-21, Volume: 116, Issue:1169 Topics: Caseins; Child; Child, Preschool; Comorbidity; Dairy Products; Diabetes Mellitus, Type 1; Europe; Humans; Myocardial Ischemia; Smoking	2003
Balancing research for new risk factors and action for the prevention of chronic diseases. The New Zealand medical journal, 2003, Jan-24, Volume: 116, Issue:1168 Topics: Animals; Cardiovascular Diseases; Caseins; Cattle; Chronic Disease; Coronary Disease; Diabetes Mellitus, Type 1; Epidemiologic Research Design; Humans; Milk; New Zealand; Research Support as Topic; Risk Factors	2003
Ischaemic heart disease, Type 1 diabetes, and cow milk A1 beta-casein. The New Zealand medical journal, 2003, Jan-24, Volume: 116, Issue:1168 Topics: Adolescent; Adult; Animals; Caseins; Cattle; Child; Child, Preschool; Dairy Products; Diabetes Mellitus, Type 1; Europe; Food Supply; Humans; Infant; Infant, Newborn; Japan; Milk; Multivariate Analysis; Myocardial Ischemia; Population Surveillance; Species Specificity; Survival Rate	2003
Short-term dietary adjustment with a hydrolyzed casein-based diet postpones diabetes development in the diabetes-prone BB rat. Metabolism: clinical and experimental, 2003, Volume: 52, Issue:3 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Dietary Proteins; Genetic Predisposition to Disease; Hydrolysis; Interferon-gamma; Interleukin-10; Intestinal Mucosa; Lymph Nodes; Lymphocytes; Mesentery; Rats; Rats, Inbred BB; Time Factors; Weaning	2003
The influence of consumption of A1 beta-casein on heart disease and Type 1 diabetes--the authors reply. The New Zealand medical journal, 2003, Mar-14, Volume: 116, Issue:1170 Topics: Adult; Animals; Caseins; Cheese; Child; Diabetes Mellitus, Type 1; Female; Humans; Infant; Male; Middle Aged; Milk; Myocardial Ischemia; Smoking	2003
A1 beta-casein milk and Type 1 diabetes: causal relationship probed in animal models. The New Zealand medical journal, 2003, Mar-14, Volume: 116, Issue:1170 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Disease Models, Animal; Humans; Mice; Milk; Rats	2003
Setting the record straight: A1 beta-casein, heart disease and diabetes. The New Zealand medical journal, 2003, Mar-14, Volume: 116, Issue:1170 Topics: Adolescent; Adult; Aged; Animals; Caseins; Cattle; Child; Child, Preschool; Diabetes Mellitus, Type 1; Humans; Incidence; Male; Middle Aged; Milk; Myocardial Ischemia	2003
Oligofructose does not affect the development of type 1 diabetes mellitus induced by dietary proteins in the diabetes-prone BB rat model. Diabetes, nutrition & metabolism, 2003, Volume: 16, Issue:2 Topics: Animals; Blood Glucose; Caseins; Cellulose; Diabetes Mellitus, Type 1; Diet; Dietary Proteins; Disease Models, Animal; Female; Incidence; Intestinal Mucosa; Male; Oligosaccharides; Rats; Rats, Inbred BB	2003
Cow's milk and trials for prevention of Type 1 diabetes. Diabetic medicine : a journal of the British Diabetic Association, 2003, Volume: 20, Issue:11 Topics: Animals; Autoantibodies; Caseins; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Genotype; Humans; Infant Formula; Infant, Newborn; Milk; Risk Factors; Vitamin D	2003
The influence of oral insulin on the development of autoimmune diabetes in NOD mice fed a hypoallergenic diet. Diabetes, nutrition & metabolism, 2004, Volume: 17, Issue:1 Topics: Administration, Oral; Animals; Caseins; Diabetes Mellitus, Type 1; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Incidence; Insulin; Islets of Langerhans; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Protein Hydrolysates; Random Allocation	2004
Serum antibodies to the major proteins found in cow's milk of Iranian patients with Type 1 diabetes mellitus. Diabetes, nutrition & metabolism, 2004, Volume: 17, Issue:2 Topics: Adolescent; Animals; Antibodies; Breast Feeding; Caseins; Cattle; Child; Child, Preschool; Dairy Products; Diabetes Mellitus, Type 1; Diet; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin M; Infant; Infant Food; Iran; Milk; Milk Proteins; Surveys and Questionnaires	2004
Further research for consideration in 'the A2 milk case'. European journal of clinical nutrition, 2006, Volume: 60, Issue:7 Topics: Animals; Caseins; Coronary Disease; Diabetes Mellitus, Type 1; Endorphins; Humans; Milk; Peptide Fragments	2006
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia. Annals of nutrition & metabolism, 2006, Volume: 50, Issue:3 Topics: Adolescent; Age Factors; Animals; Caseins; Cattle; Child; Child, Preschool; Dairy Products; Diabetes Mellitus, Type 1; Diet Surveys; Female; Health Surveys; Humans; Iceland; Incidence; Male; Scandinavian and Nordic Countries	2006
Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? Diabetologia, 2006, Volume: 49, Issue:9 Topics: Animals; Anti-Bacterial Agents; Bacteroides; Caseins; Diabetes Mellitus, Type 1; Female; In Situ Hybridization, Fluorescence; Intestines; Male; Microscopy, Fluorescence; Prediabetic State; Rats; Rats, Inbred BB; RNA, Ribosomal, 16S	2006
Circulating monocytes are activated in newly diagnosed type 1 diabetes mellitus patients. Clinical and experimental immunology, 1994, Volume: 98, Issue:3 Topics: Adult; Blood Cell Count; Caseins; Chemotaxis, Leukocyte; Complement C5a; Diabetes Mellitus, Type 1; Female; Humans; Male; Monocytes; Monocytes, Activated Killer; Pancreas; Phagocytosis; Respiratory Burst; Time Factors	1994
Prophylactic nutritional modification of the incidence of diabetes in autoimmune non-obese diabetic (NOD) mice. The British journal of nutrition, 1993, Volume: 69, Issue:2 Topics: Animals; Autoimmune Diseases; Caseins; Diabetes Mellitus, Type 1; Diet; Dietary Proteins; Disease Susceptibility; Female; Glycine max; Hydrolysis; Mice; Mice, Inbred NOD; Triticum; Weaning	1993
Dietary protection against diabetes in NOD mice: lack of a major change in the immune system. Diabete & metabolisme, 1995, Volume: 21, Issue:4 Topics: Aging; Analysis of Variance; Animals; Caseins; Cattle; Cyclophosphamide; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Humans; Immunity, Cellular; Immunotherapy, Adoptive; Infant; Infant Food; Lymphocyte Transfusion; Male; Mice; Mice, Inbred NOD; Protein Hydrolysates; Serum Albumin, Bovine; Sex Characteristics; Spleen; T-Lymphocytes; Thyroiditis	1995
Cellular immune response to cow's milk beta-lactoglobulin in patients with newly diagnosed IDDM. Diabetes, 1996, Volume: 45, Issue:2 Topics: Adolescent; Animals; Caseins; Cattle; Child; Child, Preschool; Diabetes Mellitus, Type 1; Humans; Infant; Lactoglobulins; Lymphocyte Activation; Milk Proteins; Ovalbumin	1996
A combined casein-free-nicotinamide diet prevents diabetes in the NOD mouse with minimum insulitis. Diabetes research and clinical practice, 1995, Volume: 29, Issue:2 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Diet, Protein-Restricted; Female; Fluorescent Antibody Technique; Incidence; Inflammation; Islets of Langerhans; Mice; Mice, Inbred NOD; Niacinamide	1995
Low incidence of autoimmune type I diabetes in BB rats fed a hydrolysed casein-based diet associated with early inhibition of non-macrophage-dependent hyperexpression of MHC class I molecules on beta cells. Diabetologia, 1995, Volume: 38, Issue:10 Topics: Aging; Animals; Caseins; Diabetes Mellitus, Type 1; Diet, Diabetic; Epithelium; Esophagus; Gene Expression; Genes, MHC Class I; Histocompatibility Antigens Class I; Islets of Langerhans; Pancreatic Diseases; Peripheral Nerves; Rats; Rats, Inbred BB; Species Specificity; Tongue	1995
Cow's milk and IDDM. Lancet (London, England), 1996, Oct-05, Volume: 348, Issue:9032 Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Humans; Milk; T-Lymphocytes	1996
Cell-mediated immune response to beta casein in recent-onset insulin-dependent diabetes: implications for disease pathogenesis. Lancet (London, England), 1996, Oct-05, Volume: 348, Issue:9032 Topics: Adolescent; Adult; Animals; Autoimmunity; Caseins; Cell Division; Diabetes Mellitus, Type 1; Female; Humans; Immunity, Cellular; Male; T-Lymphocytes; Thyroid Diseases	1996
Diabetes and cows' milk. Lancet (London, England), 1996, Dec-14, Volume: 348, Issue:9042 Topics: Animals; Autoimmunity; Caseins; Cattle; Cross Reactions; Diabetes Mellitus, Type 1; Humans; Milk; Monosaccharide Transport Proteins; T-Lymphocytes; Thyroid Diseases	1996
Diabetes and cows' milk. Sardinian IDDM Study Groups. Lancet (London, England), 1996, Dec-14, Volume: 348, Issue:9042 Topics: Animals; Caseins; Cattle; Diabetes Mellitus, Type 1; Humans; Immunoglobulin G; Milk Proteins; T-Lymphocytes	1996
Immunological aspects of nutritional diabetes prevention in NOD mice: a pilot study for the cow's milk-based IDDM prevention trial. Diabetes, 1997, Volume: 46, Issue:4 Topics: Adoptive Transfer; Animals; Autoantigens; Caseins; Cattle; Cross Reactions; Diabetes Mellitus, Type 1; Diet; Disease Models, Animal; Female; Hydrolysis; Incidence; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred NOD; Ovalbumin; Pancreas; Pilot Projects; Serum Albumin; Spleen; T-Lymphocytes; Time Factors	1997
Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat. Diabetes, 1997, Volume: 46, Issue:7 Topics: Animals; Caseins; Cattle; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diet; Disease Models, Animal; Female; Incidence; Male; Milk; Milk Proteins; Rats; Rats, Inbred BB; Serum Albumin	1997
Cellular immune responses to beta casein: elevated in but not specific for individuals with Type I diabetes mellitus. Diabetologia, 1998, Volume: 41, Issue:6 Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Antibody Formation; Antigens; Autoantibodies; Caseins; Cell Division; Child; Child, Preschool; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Female; HLA Antigens; Humans; Immunity, Cellular; Leukocytes, Mononuclear; Male; Phytohemagglutinins; Sex Factors; Tetanus Toxoid	1998
Proglucagon and glucose transporter mRNA is altered by diet and disease susceptibility in 30-day-old biobreeding (BB) diabetes-prone and normal rats. Pediatric research, 1998, Volume: 44, Issue:1 Topics: Animals; Caseins; Colon; Diabetes Mellitus, Type 1; Dietary Proteins; Disease Susceptibility; Female; Glucagon; Glucose Transporter Type 5; Glycine max; Intestine, Small; Male; Monosaccharide Transport Proteins; Organ Size; Proglucagon; Protein Precursors; Rats; Rats, Inbred BB; RNA, Messenger; Stomach	1998
Type I (insulin-dependent) diabetes mellitus and cow milk: casein variant consumption. Diabetologia, 1999, Volume: 42, Issue:3 Topics: Adolescent; Amino Acid Sequence; Animals; Canada; Caseins; Cattle; Child; Child, Preschool; Diabetes Mellitus, Type 1; Endorphins; Europe; Female; Genetic Variation; Humans; Incidence; Infant; Milk; Milk Proteins; New Zealand; Peptide Fragments; United States	1999
Cellular and humoral immunity against cow's milk proteins in type 1 diabetes. Journal of autoimmunity, 1999, Volume: 13, Issue:3 Topics: Adolescent; Adult; Animals; Antibody Formation; B-Lymphocytes; Caseins; Cattle; Cell Division; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Humans; Immunity, Cellular; Infant; Lactoglobulins; Male; Middle Aged; Milk Proteins; Serum Albumin, Bovine; T-Lymphocytes	1999
Effects of a protective hydrolyzed casein diet upon the metabolic and secretory responses of pancreatic islets to IL-1beta, cytokine production by mesenteric lymph node cells, mitogenic and biosynthetic activities in Peyer's patch cells, and mitogenic act Molecular genetics and metabolism, 1999, Volume: 68, Issue:3 Topics: Animals; Caseins; Cytokines; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Hydrolysis; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Lymph Nodes; Lymphocytes; Male; Pancreas; Peyer's Patches; Rats; Rats, Inbred BB	1999
[The significance of A1 and A2 antibodies against beta-casein in type-1 diabetes mellitus]. Deutsche medizinische Wochenschrift (1946), 1999, Dec-17, Volume: 124, Issue:50 Topics: Adolescent; Adult; Aged; Aging; Antibodies; Autoimmunity; Caseins; Child; Child, Preschool; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Genetic Predisposition to Disease; Humans; Infant; Male; Middle Aged; Prospective Studies	1999
Different beta-casein fractions in Icelandic versus Scandinavian cow's milk may influence diabetogenicity of cow's milk in infancy and explain low incidence of insulin-dependent diabetes mellitus in Iceland. Pediatrics, 2000, Volume: 106, Issue:4 Topics: Adolescent; Animals; Breast Feeding; Case-Control Studies; Caseins; Child; Child, Preschool; Diabetes Mellitus, Type 1; Humans; Iceland; Incidence; Infant; Milk; Retrospective Studies; Scandinavian and Nordic Countries	2000
T cells of multiple sclerosis patients target a common environmental peptide that causes encephalitis in mice. Journal of immunology (Baltimore, Md. : 1950), 2001, Apr-01, Volume: 166, Issue:7 Topics: Adult; Amino Acid Sequence; Animals; Butyrophilins; Caseins; Cattle; Cross Reactions; Diabetes Mellitus, Type 1; Encephalomyelitis, Autoimmune, Experimental; Epitopes, T-Lymphocyte; Humans; Lactoglobulins; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Milk Proteins; Molecular Sequence Data; Multiple Sclerosis; Peptide Fragments; Peptide Mapping; Serum Albumin, Bovine; T-Lymphocytes; Virulence Factors, Bordetella	2001
Intradermal skin test with diabetes specific antigens in patients with type 1 diabetes. Clinical and experimental immunology, 2001, Volume: 123, Issue:3 Topics: Adolescent; Adult; Caseins; Child; Diabetes Mellitus, Type 1; Female; Glutamate Decarboxylase; Humans; Hypersensitivity, Delayed; Insulin; Intradermal Tests; Isoenzymes; Male; Middle Aged	2001
Feeding a protective hydrolysed casein diet to young diabetic-prone BB rats affects oxidation of L[U-14C]glutamine in islets and Peyer's patches, reduces abnormally high mitotic activity in mesenteric lymph nodes, enhances islet insulin and tends to norma International journal of experimental diabetes research, 2000, Volume: 1, Issue:2 Topics: Administration, Oral; Animal Feed; Animals; Blood Glucose; Caseins; Diabetes Mellitus, Type 1; Dietary Proteins; Disease Models, Animal; Female; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Lymph Nodes; Male; Mitosis; Nitric Oxide; Oxidation-Reduction; Peyer's Patches; Protein Hydrolysates; Rats; Rats, Inbred BB; Reference Values; Weight Gain	2000
Oral exposure to diabetes-promoting food or immunomodulators in neonates alters gut cytokines and diabetes. Diabetes, 2002, Volume: 51, Issue:1 Topics: Adjuvants, Immunologic; Animal Feed; Animals; Animals, Newborn; Caseins; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Animal; Edible Grain; Gene Expression Regulation; Glutens; Humans; Immunity, Mucosal; Infant; Infant Food; Inflammation; Islets of Langerhans; Lipopolysaccharides; Protein Hydrolysates; Rats; Rats, Inbred BB	2002
Cell-mediated immune responses to GAD and beta-casein in type 1 diabetes mellitus in Thailand. Diabetes research and clinical practice, 2002, Volume: 55, Issue:3 Topics: Animals; Autoantibodies; Caseins; Cattle; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glutamate Dehydrogenase; Humans; Immunity, Cellular; Lymphocyte Activation; Reference Values; Regression Analysis; Reproducibility of Results; Thailand	2002
Impact of dietary protein and fat source on the development of insulin-dependent diabetes in the BB rat. Diabetes research (Edinburgh, Scotland), 1992, Volume: 20, Issue:1 Topics: Animal Feed; Animals; Caseins; Diabetes Mellitus, Type 1; Dietary Fats; Dietary Proteins; Fabaceae; Fish Oils; Geography; Humans; Mice; Mice, Inbred NOD; Plants, Medicinal; Prevalence; Rats; Rats, Inbred BB; Soybean Oil	1992