casein-hydrolysate and Laryngopharyngeal-Reflux

Cow's milk allergy (CMA) is treated in formula-fed infants with an extensive protein hydrolysate. This study aimed to evaluate the nutritional safety of a non-thickened and thickened extensively casein hydrolyzed protein formula (NT- and T-eCHF) in infants with CMA.. Infants younger than 6 mo old with a positive cow milk challenge test, positive IgE, or skin prick test for cow milk were selected. Weight and length were followed during the 6 mo intervention with the NT-eCHF and T-eCHF.. A challenge was performed in 50/71 infants with suspected CMA and was positive in 34/50. All children with confirmed CMA tolerated the eCHF. The T-eCHF leads to a significant improvement of the stool consistency in the whole population and in the subpopulation of infants with proven CMA. Height and weight evolution was satisfactory throughout the 6 mo study.. The eCHF fulfills the criteria of a hypoallergenic formula and the NT- and T-eCHF reduced CMA symptoms. Growth was within normal range.

Topics: Animals; Body Height; Body Weight; Caseins; Child Development; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Dietary Proteins; Double-Blind Method; Energy Intake; Female; Humans; Immunoglobulin E; Infant; Infant Formula; Laryngopharyngeal Reflux; Male; Milk; Milk Hypersensitivity; Prospective Studies; Protein Hydrolysates; Viscosity