caryophyllene-oxide and Pain

caryophyllene-oxide has been researched along with Pain* in 2 studies

Other Studies

2 other study(ies) available for caryophyllene-oxide and Pain

ArticleYear
[GC-MS analysis and analgesic activity of essential oil from fresh rhizoma of Cyperus rotundus].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:8

    To observe the analgesic effect and analysis the chemical components of essential oil (EOC) from fresh rhizome of Cyperus rotundus.. Hydrodistillation method was used to extract EOC; Acetic acid induced mice stretching model was applied to evaluate the analgesic effect of EOC. Gas chromatography coupled with mass spectrometry (GC-MS) were applied for the analysis of EOC.. The yield of EOC was 0.4%. The stretching times of mice induced by acetic acid were significantly reduced by EOC at dosage of 0.1 g/kg. 54 ingredients, 85.1% of which were EOC were identified by GC-MS analysis; The major compounds were cyperene (41.03%), beta-caryophyllene oxide (5.32%), alpha-selinene (4.37%), alpha-copaene (4.36%), naphthalene, 6-isoproenyl-4,8a-dimethyl-1, 2, 3, 5, 6, 7, 8, 8a-octahydro-(3.80%) and alpha-cyperone (3.11%).. The essential oil from fresh rhizome of Cyperus rotundus shows structure diversity and good analgesic effect.

    Topics: Acetic Acid; Analgesics; Animals; Cyperus; Disease Models, Animal; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Mice; Oils, Volatile; Pain; Pain Threshold; Plants, Medicinal; Polycyclic Sesquiterpenes; Rhizome; Sesquiterpenes; Solvents

2011
Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:2

    Caryophyllene oxide was isolated from an unsaponified petroleum ether extract of the bark of Annona squamosa and studied for its analgesic and anti-inflammatory activity. Caryophyllene oxide at the doses of 12.5 and 25mg/kg body wt. and unsaponified petroleum ether extract at a dose of 50mg/kg body wt. showed significant central as well as peripheral analgesic, along with anti-inflammatory, activity. These activities of caryophyllene oxide were comparable with the standard drug used in the respective experiments.

    Topics: Acetic Acid; Analgesics; Animals; Annona; Anti-Inflammatory Agents; Carrageenan; Edema; Female; Hot Temperature; Male; Mice; Pain; Phytotherapy; Plant Bark; Plant Extracts; Polycyclic Sesquiterpenes; Rats; Rats, Wistar; Sesquiterpenes

2010