caryophyllene and Sexually-Transmitted-Diseases

Obesity is an excessive accumulation of fat that exacerbates the metabolic and inflammatory processes. Studies associate these processes with conditions and dysregulation in the intestinal tract, increased concentrations of lipopolysaccharides (LPSs) in the blood, differences in the abundance of intestinal microbiota, and the production of secondary metabolites such as short-chain fatty acids. β-Caryophyllene (BCP) is a natural sesquiterpene with anti-inflammatory properties and with the potential purpose of fighting metabolic diseases. A diet-induced obesity model was performed in 16-week-old C57BL/6 mice administered with BCP [50 mg/kg]. A reduction in the expression of Claudin-1 was observed in the group with a high-fat diet (HFD), which was caused by the administration of BCP; besides BCP, the

Topics: Animals; Claudin-1; Diet, High-Fat; Fatty Acids; Gastrointestinal Diseases; Leptin; Mice; Mice, Inbred C57BL; Obesity; Polycyclic Sesquiterpenes; Sesquiterpenes; Sexually Transmitted Diseases