caryophyllene has been researched along with Pneumonia* in 1 studies
1 other study(ies) available for caryophyllene and Pneumonia
| Article | Year |
|---|---|
The cannabinoid 2 receptor agonist β-caryophyllene modulates the inflammatory reaction induced by Mycobacterium bovis BCG by inhibiting neutrophil migration.
β-Caryophyllene (BCP) is a sesquiterpene that binds to the cannabinoid 2 (CB. C57Bl/6 mice were pretreated orally with BCP (0.5-50 mg/kg) or intraperitonealy with GP1a (10 mg/kg) 1 h before the induction of pleurisy or pulmonary inflammation by BCG. The direct action of CB. β-Caryophyllene (50 mg/kg) impaired BCG-induced neutrophil accumulation in pleurisy without affecting mononuclear cells or the production of TNF-α and CCL2/MCP-1. However, BCP inhibited CXCL1/KC, leukotriene B. These results suggest that the CB Topics: Actins; Animals; Anti-Inflammatory Agents; Cell Adhesion; Cell Line; Cell Movement; Cytokines; Dinoprostone; Macrophages; Male; Mice, Inbred C57BL; Mycobacterium bovis; Neutrophils; Nitric Oxide; Pleurisy; Pneumonia; Polycyclic Sesquiterpenes; Receptor, Cannabinoid, CB2; Sesquiterpenes; Tuberculosis, Pulmonary | 2016 |