Page last updated: 2024-10-24

carvedilol and Obesity

carvedilol has been researched along with Obesity in 5 studies

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Catecholamine excess reflecting an adrenergic overdrive of the sympathetic nervous system (SNS) has been proposed to link to hyperleptinemia in obesity and may contribute to the development of metabolic disorders."7.91Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice. ( Baker, S; Dang, TB; Doan, KV; Kim, KW; Le Tran, T; Nguyen, LV; Nguyen, PH; Nguyen, T; Nguyen, TH; Pham, TVH; Ta, QV; Yang, DJ, 2019)
"To study efficacy and safety of a preparation of carvedilol Acridilol (Akrikhin, Russia) in patients with mild and moderate arterial hypertension (AH) and obesity and/or compensated type 2 diabetes mellitus (DM)."5.13[First results of open randomized clinical study of Acridilol in combination therapy of patients with arterial hypertension and obesity or type 2 diabetes (Mellitus-Open Multicenter Clinical Study ACCORD)]. ( Deev, AD; Lukina, IuV; Martsevich, SIu; Oganov, RG; Shal'nova, SA, 2008)
"40 rats were randomly divided into 4 groups: control, untreated atherosclerosis group, atherosclerotic rats treated with carvedilol (10mg/kg/d) and atherosclerotic rats treated with alendronate sodium (10mg/kg/d)."4.02Matrix metalloproteinase 9 a potential major player connecting atherosclerosis and osteoporosis in high fat diet fed rats. ( Abdelgwad, M; Estaphan, S; Kamar, S; Mostafa, S; Rashed, L; Sabry, M, 2021)
"Catecholamine excess reflecting an adrenergic overdrive of the sympathetic nervous system (SNS) has been proposed to link to hyperleptinemia in obesity and may contribute to the development of metabolic disorders."3.91Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice. ( Baker, S; Dang, TB; Doan, KV; Kim, KW; Le Tran, T; Nguyen, LV; Nguyen, PH; Nguyen, T; Nguyen, TH; Pham, TVH; Ta, QV; Yang, DJ, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Yamamoto, PA1
Cristofoletti, R1
Vozmediano, V1
de Gaitani, CM1
da Silva, RM1
Kemp, R1
Sankarankutty, AK1
Salgado Junior, W1
Santos, JSD1
de Moraes, NV1
Nguyen, LV1
Ta, QV1
Dang, TB1
Nguyen, PH1
Nguyen, T1
Pham, TVH1
Nguyen, TH1
Baker, S1
Le Tran, T1
Yang, DJ1
Kim, KW1
Doan, KV1
Sabry, M1
Mostafa, S1
Rashed, L1
Abdelgwad, M1
Kamar, S1
Estaphan, S1
Wang, Q1
Liu, Y1
Fu, Q1
Xu, B1
Zhang, Y1
Kim, S1
Tan, R1
Barbagallo, F1
West, T1
Anderson, E1
Wei, W1
Abel, ED1
Xiang, YK1
Shal'nova, SA1
Martsevich, SIu1
Deev, AD1
Lukina, IuV1
Oganov, RG1

Trials

1 trial available for carvedilol and Obesity

ArticleYear
[First results of open randomized clinical study of Acridilol in combination therapy of patients with arterial hypertension and obesity or type 2 diabetes (Mellitus-Open Multicenter Clinical Study ACCORD)].
    Kardiologiia, 2008, Volume: 48, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilo

2008

Other Studies

4 other studies available for carvedilol and Obesity

ArticleYear
Effect of Roux-En-Y Gastric Bypass in the Pharmacokinetics of (R)-Carvedilol and (S)-Carvedilol.
    Journal of clinical pharmacology, 2023, Volume: 63, Issue:7

    Topics: Carvedilol; Comorbidity; Gastric Bypass; Humans; Obesity; Obesity, Morbid

2023
Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Adipose Tissue, White; Administration, Oral; Adrenergic Agents; Adrenergic beta-Antagonists; Animals

2019
Matrix metalloproteinase 9 a potential major player connecting atherosclerosis and osteoporosis in high fat diet fed rats.
    PloS one, 2021, Volume: 16, Issue:2

    Topics: Alendronate; Alkaline Phosphatase; Animals; Atherosclerosis; Biomarkers; Bone Density; Bone Remodeli

2021
Inhibiting Insulin-Mediated β2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction.
    Circulation, 2017, Jan-03, Volume: 135, Issue:1

    Topics: Animals; beta-Arrestin 2; Carbazoles; Carvedilol; Cells, Cultured; Cyclic Nucleotide Phosphodiestera

2017