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carvedilol and Muscular Dystrophy, Duchenne

carvedilol has been researched along with Muscular Dystrophy, Duchenne in 4 studies

Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of carvedilol for left ventricular dysfunction in Duchenne muscular dystrophy (DMD), we enrolled 8 patients with DMD who had elevated plasma atrial natriuretic peptide (ANP) or brain natriuretic peptide (BNP), and a low ejection fraction (EF < 40%) in echocardiography."3.71[Carvedilol effectiveness for left ventricular-insufficient patients with Duchenne muscular dystrophy]. ( Matsumura, T; Miyai, I; Nozaki, S; Saito, T; Shinno, S, 2001)
"Heart failure is one of the most serious complications in Duchenne muscular dystrophy (DMD)."2.75Carvedilol can prevent cardiac events in Duchenne muscular dystrophy. ( Kawai, M; Kikuchi, Y; Kuru, S; Matsumura, T; Tamura, T, 2010)
"Patients with Becker muscular dystrophy-related cardiomyopathy typically survive into their 30s, when they succumb to complications of cardiomyopathy or receive heart transplants."1.31Becker muscular dystrophy-related cardiomyopathy: a favorable response to medical therapy. ( Doing, AH; Renlund, DG; Smith, RA, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barison, A1
Aquaro, GD1
Passino, C1
Falorni, M1
Balbarini, A1
Lombardi, M1
Pasquali, L1
Emdin, M1
Siciliano, G1
Matsumura, T2
Tamura, T1
Kuru, S1
Kikuchi, Y1
Kawai, M1
Doing, AH1
Renlund, DG1
Smith, RA1
Saito, T1
Miyai, I1
Nozaki, S1
Shinno, S1

Trials

1 trial available for carvedilol and Muscular Dystrophy, Duchenne

ArticleYear
Carvedilol can prevent cardiac events in Duchenne muscular dystrophy.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:14

    Topics: Adolescent; Adult; Carbazoles; Carvedilol; Child; Chronic Disease; Heart Failure; Humans; Longitudin

2010

Other Studies

3 other studies available for carvedilol and Muscular Dystrophy, Duchenne

ArticleYear
Cardiac magnetic resonance imaging and management of dilated cardiomyopathy in a Duchenne muscular dystrophy manifesting carrier.
    Journal of neurology, 2009, Volume: 256, Issue:2

    Topics: Adult; Biomarkers; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Child; Creatine Kinase; Disease

2009
Becker muscular dystrophy-related cardiomyopathy: a favorable response to medical therapy.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2002, Volume: 21, Issue:4

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Carbazoles; Cardiomyopat

2002
[Carvedilol effectiveness for left ventricular-insufficient patients with Duchenne muscular dystrophy].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:10

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Humans; Muscular Dystrophy,

2001