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carvedilol and Injury, Ischemia-Reperfusion

carvedilol has been researched along with Injury, Ischemia-Reperfusion in 23 studies

Research Excerpts

ExcerptRelevanceReference
"Carvedilol is an alpha1 and nonselective beta-adrenergic receptor antagonist with antioxidative properties known to protect against reperfusion injury in the heart, brain, and kidneys."7.70Carvedilol reduces ischaemic skeletal muscle necrosis. ( Hvaal, K; Kirkeby, OJ; Mathisen, SR; Skjeldal, S; Svindland, A, 1999)
"Carvedilol treatment decreased the detrimental effects induced by R-IRI."5.62Quercetin and lithium chloride potentiate the protective effects of carvedilol against renal ischemia-reperfusion injury in high-fructose, high-fat diet-fed Swiss albino mice independent of renal lipid signaling. ( Ibrahim, IAAE; Mahmoud, AAA; Mahmoud, MF; Rezk, AM, 2021)
"Treatment with carvedilol significantly decreased plasma creatinine levels after IRI (up to 168 hr) compared to controls (P < 0."5.36Carvedilol protects tubular epithelial cells from ischemia-reperfusion injury by inhibiting oxidative stress. ( De Velasco, MA; Hayashi, T; Ishii, T; Nishioka, T; Nose, K; Saitou, Y; Uemura, H, 2010)
" In addition, factors potentially involved in hepatic ischemia-reperfusion injury, including oxidative stress (malondialdehyde and superoxide anion levels), mitochondrial damage (glutamate dehydrogenase activity), microcirculatory disorders (flow rate and vascular resistance), and adenosine triphosphate (ATP) depletion, were evaluated after reperfusion."3.76Addition of carvedilol to University Wisconsin solution improves rat steatotic and nonsteatotic liver preservation. ( Alfany-Fernandez, I; Ben Abdennebi, H; Ben Mosbah, I; Boillot, O; Lojek, A; Mitjavila, MT; Parellada, PP; Peralta, C; Rimola, A; Rodés, J; Roselló-Catafau, J, 2010)
"Carvedilol is an alpha1 and nonselective beta-adrenergic receptor antagonist with antioxidative properties known to protect against reperfusion injury in the heart, brain, and kidneys."3.70Carvedilol reduces ischaemic skeletal muscle necrosis. ( Hvaal, K; Kirkeby, OJ; Mathisen, SR; Skjeldal, S; Svindland, A, 1999)
"Carvedilol, a selective alpha(1) and non-selective beta-adrenoceptor antagonist and antioxidant, has been shown to provide significant cardiac protection in animal models of myocardial ischemia."3.70Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model. ( Chen, J; Christopher, TA; Gao, F; Gu, J; Lopez, BL; Lysko, P; Ma, XL; Ohlstein, EH; Ruffolo, RR; Yue, TL, 2000)
"Carvedilol treatment decreased the detrimental effects induced by R-IRI."1.62Quercetin and lithium chloride potentiate the protective effects of carvedilol against renal ischemia-reperfusion injury in high-fructose, high-fat diet-fed Swiss albino mice independent of renal lipid signaling. ( Ibrahim, IAAE; Mahmoud, AAA; Mahmoud, MF; Rezk, AM, 2021)
"Treatment with carvedilol significantly decreased plasma creatinine levels after IRI (up to 168 hr) compared to controls (P < 0."1.36Carvedilol protects tubular epithelial cells from ischemia-reperfusion injury by inhibiting oxidative stress. ( De Velasco, MA; Hayashi, T; Ishii, T; Nishioka, T; Nose, K; Saitou, Y; Uemura, H, 2010)
"Carvedilol is a recently introduced drug with multiple action with a non-selective beta-antiadrenergic and selective alpha1-antiadrenergic action used for treatment of mild to medium severe hypertension."1.30[The effects of Carvedilol, a beta-blocker, in experimental ischemia-reperfusion kidney injury]. ( Bartosíková, L; Drápelová, L; Husek, K; Kuchtícková, S; Necas, J; Pavlícek, V, 1997)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (17.39)18.2507
2000's7 (30.43)29.6817
2010's9 (39.13)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Kafadar, MT1
Gök, MA1
Mohammed, SG1
Ibrahim, IAAE2
Mahmoud, MF2
Mahmoud, AAA2
Rezk, AM1
Hassan, MI1
Ali, FE1
Shalkami, AS1
Chen, Z1
Wu, Y1
Duan, J1
Zhu, B1
Yang, L1
Harima, M1
Arumugam, S1
Wen, J1
Pitchaimani, V1
Karuppagounder, V1
Afrin, MR1
Sreedhar, R1
Miyashita, S1
Nomoto, M1
Ueno, K1
Nakamura, M1
Watanabe, K1
Özsoy, AZ1
Nursal, AF1
Arıcı, A1
Bütün, İ1
Uysal, M1
Irmak Sapmaz, H1
Kunt İşgüder, Ç1
Yılmaz Doğru, H1
Taş, U1
Park, KM1
Teoh, JP1
Wang, Y1
Broskova, Z1
Bayoumi, AS1
Tang, Y1
Su, H1
Weintraub, NL1
Kim, IM1
Hayashi, T2
Saitou, Y2
Nose, K2
Nishioka, T2
Ishii, T2
Uemura, H2
Usta, E1
Renovanz, M1
Mustafi, M1
Ziemer, G1
Aebert, H1
Ben Mosbah, I1
Roselló-Catafau, J1
Alfany-Fernandez, I1
Rimola, A1
Parellada, PP1
Mitjavila, MT1
Lojek, A1
Ben Abdennebi, H1
Boillot, O1
Rodés, J1
Peralta, C1
De Velasco, MA1
Lai, MK1
Yamagata, K1
Ichinose, S1
Tagami, M1
Singh, D1
Chander, V1
Chopra, K1
Strosznajder, RP1
Jesko, H1
Dziewulska, J1
Igarashi, N1
Nozawa, T1
Fujii, N1
Suzuki, T1
Matsuki, A1
Nakadate, T1
Igawa, A1
Inoue, H1
Vacek, L1
Husek, K2
Christopher, TA2
Lopez, BL2
Ma, XL2
Feuerstein, GZ1
Ruffolo, RR2
Yue, TL2
Necas, J1
Bartosíková, L1
Drápelová, L1
Pavlícek, V1
Kuchtícková, S1
Hvaal, K1
Mathisen, SR1
Svindland, A1
Kirkeby, OJ1
Skjeldal, S1
Gao, F1
Chen, J1
Gu, J1
Lysko, P1
Ohlstein, EH1
Horio, T1
Ito, S1
Aoyama, M1
Takeda, Y1
Suzumura, H1
Nakata, K1
Yamada, Y1
Suzuki, S1
Fukutomi, T1
Itoh, M1

Other Studies

23 other studies available for carvedilol and Injury, Ischemia-Reperfusion

ArticleYear
Effects of Carvedilol on liver ischemia-reperfusion injury in rats.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2022, Volume: 28, Issue:7

    Topics: Animals; Carvedilol; Caspase 3; Glutathione; Liver; Rats; Rats, Wistar; Reperfusion Injury; Tumor Ne

2022
Carvedilol protects against hepatic ischemia/reperfusion injury in high-fructose/high-fat diet-fed mice: Role of G protein-coupled receptor kinase 2 and 5.
    Toxicology and applied pharmacology, 2019, 11-01, Volume: 382

    Topics: Animals; Carvedilol; Diet, High-Fat; Fructose; G-Protein-Coupled Receptor Kinase 2; G-Protein-Couple

2019
Quercetin and lithium chloride potentiate the protective effects of carvedilol against renal ischemia-reperfusion injury in high-fructose, high-fat diet-fed Swiss albino mice independent of renal lipid signaling.
    Chemico-biological interactions, 2021, Jan-05, Volume: 333

    Topics: Animals; Apoptosis; Carvedilol; Cytoprotection; Diet, High-Fat; Drug Synergism; Fructose; Kidney; Li

2021
Role of TLR-4/IL-6/TNF-α, COX-II and eNOS/iNOS pathways in the impact of carvedilol against hepatic ischemia reperfusion injury.
    Human & experimental toxicology, 2021, Volume: 40, Issue:8

    Topics: Adrenergic Antagonists; Animals; Anti-Inflammatory Agents; Carvedilol; Cyclooxygenase 2; Interleukin

2021
Carvedilol exerts myocardial protection via regulation of AMPK-mTOR-dependent autophagy?
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 118

    Topics: AMP-Activated Protein Kinases; Autophagy; Carvedilol; Humans; Reperfusion Injury; Signal Transductio

2019
Effect of carvedilol against myocardial injury due to ischemia-reperfusion of the brain in rats.
    Experimental and molecular pathology, 2015, Volume: 98, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Apoptosis; Blood Pressure; Brain; Carbazoles; Carvedilol; Hear

2015
Effects of carvedilol on an ischemia/reperfusion model: Biochemical, histopathological and immunohistochemical evaluation.
    The journal of obstetrics and gynaecology research, 2016, Volume: 42, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Apoptosis; bcl-2-Associated X Protein; Carbazoles;

2016
Carvedilol-responsive microRNAs, miR-199a-3p and -214 protect cardiomyocytes from simulated ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2016, 08-01, Volume: 311, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Apoptosis; Carbazoles; Carvedilol; Cell Line; Cells, Cultured;

2016
Efficacy of carvedilol for ischemia/reperfusion-induced oxidative renal injury in rats.
    Transplantation proceedings, 2008, Volume: 40, Issue:7

    Topics: Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Creatinine; Kidney; Kidney Function Tests;

2008
Human cardiac tissue in a microperfusion chamber simulating extracorporeal circulation--ischemia and apoptosis studies.
    Journal of cardiothoracic surgery, 2010, Jan-18, Volume: 5

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Apoptosis; Biopsy; Calcium; Carbazoles; Carvedilo

2010
Addition of carvedilol to University Wisconsin solution improves rat steatotic and nonsteatotic liver preservation.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Adenylate Kinase; Adrenergic beta-Antagonists; Allopurinol; Anima

2010
Carvedilol protects tubular epithelial cells from ischemia-reperfusion injury by inhibiting oxidative stress.
    International journal of urology : official journal of the Japanese Urological Association, 2010, Volume: 17, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Apoptosis; Carbazoles; Carvedilol; Cr

2010
Editorial comment to carvedilol protects tubular epithelial cells from ischemia-reperfusion injury by inhibiting oxidative stress.
    International journal of urology : official journal of the Japanese Urological Association, 2010, Volume: 17, Issue:12

    Topics: Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Epithelial Cells; Humans; Kidney Tubules;

2010
Amlodipine and carvedilol prevent cytotoxicity in cortical neurons isolated from stroke-prone spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:4

    Topics: Amlodipine; Animals; Antioxidants; Carbazoles; Carvedilol; Cell Death; Cell Hypoxia; Cells, Cultured

2004
Carvedilol attenuates ischemia-reperfusion-induced oxidative renal injury in rats.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:6

    Topics: Animals; Antioxidants; Carbazoles; Carvedilol; Glutathione; Kidney; Kidney Function Tests; Lipid Per

2004
Effect of carvedilol on neuronal survival and poly(ADP-ribose) polymerase activity in hippocampus after transient forebrain ischemia.
    Acta neurobiologiae experimentalis, 2005, Volume: 65, Issue:2

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Carbazoles; Carvedilol; Cell Survival; D

2005
Influence of beta-adrenoceptor blockade on the myocardial accumulation of fatty acid tracer and its intracellular metabolism in the heart after ischemia-reperfusion injury.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Carbazoles; Carvedilol; Fatty Acids; Iodobenz

2006
[Protective effect of carvedilol on renal circulation and tissue injury in reperfusion of ischemic kidneys in rats].
    Vnitrni lekarstvi, 1994, Volume: 40, Issue:4

    Topics: Animals; Blood Flow Velocity; Carbazoles; Carvedilol; Free Radical Scavengers; Kidney; Male; Propano

1994
Effects of a hydroxylated metabolite of the beta-andrenoreceptor antagonist, carvedilol, on post-ischaemic splachnic tissue injury.
    British journal of pharmacology, 1998, Volume: 123, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Blood Pressure; Carbazoles; Carvedilol; Endothel

1998
[The effects of Carvedilol, a beta-blocker, in experimental ischemia-reperfusion kidney injury].
    Vnitrni lekarstvi, 1997, Volume: 43, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Kidney; Male; Malondialdehyde; Propano

1997
Carvedilol reduces ischaemic skeletal muscle necrosis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1999, Volume: 17, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Area Under Curve; Blood Pressure; Carbazoles; Carvedilol; Hind

1999
Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model.
    European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Bisoprolol; Carbazoles

2000
Effect of carvedilol on atrioventricular conduction in the ischemic heart.
    European journal of pharmacology, 2001, Jan-26, Volume: 412, Issue:2

    Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bundle of His

2001