Page last updated: 2024-10-24
carvedilol and Heritable Pulmonary Arterial Hypertension
carvedilol has been researched along with Heritable Pulmonary Arterial Hypertension in 1 studies
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
Grinnan, D | 1 |
Bogaard, HJ | 1 |
Grizzard, J | 1 |
Van Tassell, B | 1 |
Abbate, A | 1 |
DeWilde, C | 1 |
Priday, A | 1 |
Voelkel, NF | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status |
Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension[NCT00964678] | Phase 1/Phase 2 | 10 participants (Actual) | Interventional | 2010-06-30 | Completed |
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trial Outcomes
Absolute Change in Right Ventricular Ejection Fraction
Change in right ventricular ejection fraction is measured by cardiac magnetic resonance imaging, using the method of disks with the reading radiologist being blinded to before and after images. Cardiac magnetic resonance imaging was done at baseline and 6 months only (NCT00964678)
Timeframe: baseline, 6 months
Intervention | % RVEF (Mean) |
---|
Carvedilol | 10.4 |
Change in 6 Minute Walk Distance
(NCT00964678)
Timeframe: baseline and 6 months
Intervention | feet (Number) |
---|
| Participant 1 | Participant 2 | Participant 3 | Participant 5 | Participant 6 |
---|
Carvedilol | 45 | 160 | 35 | 5 | 96 |
Change in Right Ventricular End Systolic Volume
right ventricular end systolic volume determined by MRI (NCT00964678)
Timeframe: baseline and 6 months
Intervention | mL (Number) |
---|
| Participant 1 | Participant 2 | Participant 3 | Participant 4 | Participant 5 | Participant 6 |
---|
Carvedilol | 3 | 14 | 56 | 11 | 27 | 25 |
Change in Tricuspid Annular Plane Systolic Excursion
Higher values indicate a better outcome. (NCT00964678)
Timeframe: baseline and 6 months
Intervention | centimeters (Number) |
---|
| Participant 1 | Participant 2 | Participant 4 | Participant 5 | Participant 6 |
---|
Carvedilol | 0.4 | -0.08 | -0.12 | 0.45 | 0.08 |
Trials
1 trial available for carvedilol and Heritable Pulmonary Arterial Hypertension