Page last updated: 2024-10-24

carvedilol and Disease Exacerbation

carvedilol has been researched along with Disease Exacerbation in 34 studies

Research Excerpts

ExcerptRelevanceReference
"Carvedilol is effective in the primary prophylaxis for large oesophageal varices."9.24Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial. ( Bhadoria, AS; Bhardwaj, A; Bhatia, V; Choudhary, A; Jindal, A; Kedarisetty, CK; Kumar, G; Kumar, M; Maiwall, R; Sarin, SK; Shasthry, SM; Vashishtha, C, 2017)
"Carvedilol treatment in chronic heart failure (CHF) demonstrated to reduce mortality and rehospitalisation, and improvement of cardiac systolic function with reduction of left ventricular volumes and remodelling."9.11Effects of carvedilol on left ventricular diastolic function and chamber volumes in advanced heart failure. ( De Paola, V; Iovine, F; Martini, G; Nuti, R; Palazzuoli, A; Quatrini, I; Scali, C; Vecchiato, L, 2005)
"Carvedilol added to angiotensin-converting enzyme inhibition reduces hospitalization risk as well as severity of illness and resource utilization during admission in patients with chronic heart failure."7.71Influence of carvedilol on hospitalizations in heart failure: incidence, resource utilization and costs. U.S. Carvedilol Heart Failure Study Group. ( Bristow, MR; Cohn, JN; Colucci, WS; Fowler, MB; Gilbert, EM; Lacey, MJ; Lukas, MA; Oster, G; Packer, M; Richner, R; Vera-Llonch, M; Young, ST, 2001)
"Carvedilol is a novel multiple-action neurohormonal antagonist that has been shown to be effective in the management of congestive heart failure."6.40Carvedilol: preclinical profile and mechanisms of action in preventing the progression of congestive heart failure. ( Feuerstein, GZ; Ruffolo, RR, 1998)
"Carvedilol is effective in the primary prophylaxis for large oesophageal varices."5.24Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial. ( Bhadoria, AS; Bhardwaj, A; Bhatia, V; Choudhary, A; Jindal, A; Kedarisetty, CK; Kumar, G; Kumar, M; Maiwall, R; Sarin, SK; Shasthry, SM; Vashishtha, C, 2017)
"The effect of the beta-blocker, carvedilol, and/or ACEI on ventricular function in patients with muscular dystrophy was studied."5.12Beta-blocker therapy for cardiac dysfunction in patients with muscular dystrophy. ( Ishigaki, K; Kajimoto, H; Nakanishi, T; Nakazawa, M; Okumura, K; Osawa, M; Saito, K; Tomimatsu, H, 2006)
"Carvedilol treatment in chronic heart failure (CHF) demonstrated to reduce mortality and rehospitalisation, and improvement of cardiac systolic function with reduction of left ventricular volumes and remodelling."5.11Effects of carvedilol on left ventricular diastolic function and chamber volumes in advanced heart failure. ( De Paola, V; Iovine, F; Martini, G; Nuti, R; Palazzuoli, A; Quatrini, I; Scali, C; Vecchiato, L, 2005)
"The historical choice of angiotensin-converting enzyme (ACE) inhibition as first-line therapy in heart failure is challenged by early activation of the sympathetic system and multiple ways beta blockade (in particular, unselective agents such as carvedilol) may affect cardiac remodeling, its underlying mechanisms, and, hence, progression of heart failure, compared with ACE inhibition."4.84Beta blockers or angiotensin-converting-enzyme inhibitor/angiotensin receptor blocker: what should be first? ( Remme, WJ, 2007)
"Carvedilol added to angiotensin-converting enzyme inhibition reduces hospitalization risk as well as severity of illness and resource utilization during admission in patients with chronic heart failure."3.71Influence of carvedilol on hospitalizations in heart failure: incidence, resource utilization and costs. U.S. Carvedilol Heart Failure Study Group. ( Bristow, MR; Cohn, JN; Colucci, WS; Fowler, MB; Gilbert, EM; Lacey, MJ; Lukas, MA; Oster, G; Packer, M; Richner, R; Vera-Llonch, M; Young, ST, 2001)
"The cardioprotective properties of carvedilol (a vasodilating beta-adrenoceptor blocking agent) were studied in a rat model of dilated cardiomyopathy induced by autoimmune myocarditis."3.70Low dose carvedilol inhibits progression of heart failure in rats with dilated cardiomyopathy. ( Aizawa, Y; Fuse, K; Hanawa, H; Hasegawa, G; Higuchi, H; Hirono, S; Ito, M; Kato, K; Kodama, M; Naito, M; Nakazawa, M; Ohta, Y; Tanabe, N; Watanabe, K, 2000)
"Fatigue, but not breathlessness, remained a significant predictor for developing worsening heart failure (RR 1."2.71Symptoms in patients with heart failure are prognostic predictors: insights from COMET. ( Charlesworth, A; Cleland, JG; Ekman, I; Metra, M; Poole-Wilson, PA; Swedberg, K, 2005)
"Carvedilol treatment had a beneficial effect on lipid pattern and reduced lipid oxidation, but there was no obvious effect on progression of chronic rejection."2.69Carvedilol treatment of kidney graft recipients with chronic rejection. ( Backman, U; Fellström, B; Larsson, E; Vessby, B; Zezina, L, 1999)
"Carvedilol reduced all-cause mortality but had no effects on the Minnesota Living With Heart Failure scale, the distance walked in 9 minutes on a self-powered treadmill, or cardiothoracic index."2.68Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure. US Carvedilol Heart Failure Study Group. ( Bowers, JA; Bristow, MR; Cohn, JN; Colucci, WS; Fowler, MB; Gilbert, EM; Hershberger, R; Holcslaw, TL; Krueger, SK; Lukas, MA; Packer, M; Sackner-Bernstein, JD; Uretsky, BF; Young, ST, 1996)
"β-blockers are an important treatment of heart failure (HF) and are useful in reducing the progression of the syndrome."2.48β-blockers in stage B: a precursor of heart failure. ( Francis, GS; Sarraf, M, 2012)
" To date, controlled clinical trials performed in more than 13,000 patients with chronic heart failure have consistently shown that the long term administration of beta-blockers is associated with significant improvement in left ventricular function, clinical symptoms, and survival."2.41[Role of beta-blockers in the treatment of chronic heart heart failure]. ( Czuriga, I; Edes, I, 2001)
"This ability to decrease the risk of disease progression led to the recent approval of carvedilol for the treatment of chronic heart failure by the US Food and Drug Administration."2.40Effects of beta-adrenergic blockade on survival of patients with chronic heart failure. ( Packer, M, 1997)
"Carvedilol is a novel multiple-action neurohormonal antagonist that has been shown to be effective in the management of congestive heart failure."2.40Carvedilol: preclinical profile and mechanisms of action in preventing the progression of congestive heart failure. ( Feuerstein, GZ; Ruffolo, RR, 1998)
"Carvedilol is a multiple-action neurohormonal antagonist that is effective in slowing the progression of CHF."2.40Neurohormonal activation, oxygen free radicals, and apoptosis in the pathogenesis of congestive heart failure. ( Feuerstein, GZ; Ruffolo, RR, 1998)
"Patients with hypertension are at increased risk of developing heart failure (HF), but the mechanisms by which hypertension leads to HF have not been clarified [although left ventricular hypertrophy (LVH) is clearly a predictor of an increased risk of HF]."2.40Progression from hypertension to heart failure. Mechanisms and management. ( Cleland, JG, 1999)
"Furthermore, beta-blockers delay disease progression in CHF by reversing the pathological myocardial remodelling process that accompanies the disease."2.40Sympathetic activation and the role of beta-blockers in chronic heart failure. ( Krum, H, 1999)
"In patients with concurrent CHF and COPD, β-blockers reduced mortality, CHF exacerbation, and the need for hospitalization."1.46The evaluation of β-adrenoceptor blocking agents in patients with COPD and congestive heart failure: a nationwide study. ( Chen, CY; Huang, YB; Kuo, CC; Liao, KM; Lin, TY, 2017)
"Moreover, the rate of CHF and/or COPD exacerbation was higher in patients treated with carvedilol compared with bisoprolol (log-rank P=0."1.42Impact of β-blocker selectivity on long-term outcomes in congestive heart failure patients with chronic obstructive pulmonary disease. ( Asai, K; Furuse, E; Kubota, Y; Murai, K; Nakamura, S; Shimizu, W; Tsukada, YT, 2015)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (20.59)18.2507
2000's17 (50.00)29.6817
2010's9 (26.47)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Tanaka, S1
Imamura, T1
Ueno, H1
Kinugawa, K1
Moser-Bracher, A1
Balmer, C1
Cavigelli, A1
Satir, A1
Caduff Good, A1
Klauwer, D1
Liao, KM1
Lin, TY1
Huang, YB1
Kuo, CC1
Chen, CY1
Fonarow, G1
Textor, SC1
Rea, G1
Valente, T1
de Rosa, N1
Muto, M1
Berritto, D1
Bocchino, M1
Kubota, Y1
Asai, K1
Furuse, E1
Nakamura, S1
Murai, K1
Tsukada, YT1
Shimizu, W1
Bhardwaj, A1
Kedarisetty, CK1
Vashishtha, C1
Bhadoria, AS1
Jindal, A1
Kumar, G1
Choudhary, A1
Shasthry, SM1
Maiwall, R1
Kumar, M1
Bhatia, V1
Sarin, SK1
Crespo, MJ1
Cruz, N1
Altieri, PI1
Escobales, N1
Sehnert, AJ1
Daniels, SE1
Elashoff, M1
Wingrove, JA1
Burrow, CR1
Horne, B1
Muhlestein, JB1
Donahue, M1
Liggett, SB1
Anderson, JL1
Kraus, WE1
Jovanovic, D2
Jovovic, D2
Mihailovic-Stanojevic, N2
Miloradovic, Z2
Naumovic, R1
Dimitrijevic, J2
Maksic, N2
Djukanovic, L2
Barison, A1
Aquaro, GD1
Passino, C1
Falorni, M1
Balbarini, A1
Lombardi, M1
Pasquali, L1
Emdin, M1
Siciliano, G1
Pedersen, ME1
Cockcroft, JR1
Remme, WJ2
Sarraf, M1
Francis, GS1
Liu, J1
Takase, I1
Hakucho, A1
Okamura, N1
Fujimiya, T1
Abraham, WT2
Gilbert, EM3
Lowes, BD1
Minobe, WA1
Larrabee, P1
Roden, RL1
Dutcher, D1
Sederberg, J1
Lindenfeld, JA1
Wolfel, EE1
Shakar, SF1
Ferguson, D1
Volkman, K1
Linseman, JV1
Quaife, RA1
Robertson, AD1
Bristow, MR3
Ekman, I1
Cleland, JG2
Swedberg, K1
Charlesworth, A1
Metra, M1
Poole-Wilson, PA1
Naccarelli, GV1
Palazzuoli, A1
Quatrini, I1
Vecchiato, L1
Scali, C1
De Paola, V1
Iovine, F1
Martini, G1
Nuti, R1
Kajimoto, H1
Ishigaki, K1
Okumura, K1
Tomimatsu, H1
Nakazawa, M2
Saito, K1
Osawa, M1
Nakanishi, T1
Colucci, WS2
Packer, M3
Cohn, JN2
Fowler, MB2
Krueger, SK1
Hershberger, R1
Uretsky, BF1
Bowers, JA1
Sackner-Bernstein, JD1
Young, ST2
Holcslaw, TL1
Lukas, MA2
Ruffolo, RR2
Feuerstein, GZ2
Zezina, L1
Vessby, B1
Larsson, E1
Backman, U1
Fellström, B1
Krum, H1
Watanabe, K1
Ohta, Y1
Higuchi, H1
Hasegawa, G1
Naito, M1
Fuse, K1
Ito, M1
Hirono, S1
Tanabe, N1
Hanawa, H1
Kato, K1
Kodama, M1
Aizawa, Y1
Vera-Llonch, M1
Oster, G1
Lacey, MJ1
Richner, R1
Czuriga, I1
Edes, I1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Double-blind, Randomized Placebo-controlled Trial of Carvedilol for Early Primary Prophylaxis of Esophageal Varices in Cirrhosis.[NCT01196507]140 participants (Actual)Interventional2010-11-30Completed
Transient Elastography (FibroTouch) for Assessing Risk of Gastroesophageal Varices Bleeding in Patients With Compensated Cirrhosis (Pan-CHESS1801): An International Multicenter Study[NCT03778775]200 participants (Anticipated)Observational2018-12-14Recruiting
Prevalence of Metabolic Associated Fatty Liver Disease in Patients With Type 2 Diabetes in Jiangsu Province of China: a Prospective, Multicenter, Real-world Study[NCT05597709]2,900 participants (Anticipated)Observational2022-07-01Recruiting
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis: a Prospective Cohort Study[NCT04543643]Phase 3288 participants (Anticipated)Interventional2021-11-01Not yet recruiting
Detachable String Magnetically Controlled Capsule Endoscopy for Detecting High-risk Varices in Compensated Advanced Chronic Liver Disease (CHESS1801): A Prospective Multicenter Study[NCT03749954]105 participants (Actual)Observational2018-11-09Active, not recruiting
Effects of a Mindfulness-Based Intervention on Symptoms and Signs, Well-Being and Health in Patients With Chronic Heart Failure[NCT04871178]50 participants (Actual)Interventional2010-10-10Completed
A Multicenter,Randomized, Double Blind, Double Dummy, Parallel Group Study to Compare Effects of Coreg CR and Coreg IR on Left Ventricular End Systolic Volume Index in Subjects With Stable Chronic Heart Failure[NCT00323037]Phase 3318 participants (Actual)Interventional2006-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in BNP Levels

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-0.88
Carvedilol Controlled Release-0.86

Change From Baseline in Deceleration Time

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release24.00
Carvedilol Controlled Release53.37

Change From Baseline in Early to Late Atrial Ratio (E:A Ratio)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-0.20
Carvedilol Controlled Release-0.45

Change From Baseline in End Diastolic Dimension (EDD)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-0.33
Carvedilol Controlled Release-0.36

Change From Baseline in End Systolic Dimension (ESD)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-0.76
Carvedilol Controlled Release-0.83

Change From Baseline in Intraventricular Septal Thickness (IVST)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release.08
Carvedilol Controlled Release.05

Change From Baseline in Left Ventricular Ejection Fraction (LVEF)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release.08
Carvedilol Controlled Release.08

Change From Baseline in Left Ventricular End Diastolic Volume (LVEDV)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-36.61
Carvedilol Controlled Release-42.22

Change From Baseline in Left Ventricular End Diastolic Volume Index (LVEDVI)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-18.29
Carvedilol Controlled Release-20.57

Change From Baseline in Left Ventricular End Systolic Volume (LVESV)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release-36.61
Carvedilol Controlled Release-43.00

Change From Baseline in Left Ventricular End Systolic Volume Index (LVESVI) Characterized by 2-D Echocardiography

Maintenance Visit 3 minus Baseline. Maintenance Visit 3 occurred 24 weeks after entry into the maintenance period. The maintenance period started after completion of a titration period of variable duration. (NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

InterventionmL/m^2 (Mean)
Coreg Immediate Release-18.36
Coreg Controlled Release-20.81

Change From Baseline in Left Ventricular Mass (LVM)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release9.5
Carvedilol Controlled Release-9.29

Change From Baseline in Posterior Wall Thickness (PWT)

(NCT00323037)
Timeframe: 24 weeks after entry into the maintenance period

Interventionpercentage of change (Mean)
Carvedilol Immediate Release.07
Carvedilol Controlled Release.05

Safety and Tolerability of Coreg CR

SAEs experienced (NCT00323037)
Timeframe: 24 weeks after entry into the maintenance phase (after unblinding)

Interventionnumber of SAEs (Number)
Carvedilol Immediate Release40
Carvedilol Controlled Release35

Drug Dose Tolerability

(NCT00323037)
Timeframe: Up to 32 weeks (titration and maintenance phases)

,
Interventionsubjects in each treatment group (Number)
Study Entry (10mg Coreg CR, 3.125mg Coreg IR)Maintenance Entry (10mg Coreg CR, 3.125mg Coreg IR)End of Study (10mg Coreg CR, 3.125mg Coreg IR)Study Entry (20mg Coreg CR, 6.25mg Coreg IR)Maintenance Entry (20mg Coreg CR, 6.25mg Coreg IR)End of Study (20mg Coreg CR, 6.25mg Coreg IR)Study Entry (40mg Coreg CR, 12.5mg Coreg IR)Maintenance Entry (40mg Coreg CR, 12.5mg Coreg IR)End of Study (40mg Coreg CR, 12.5mg Coreg IR)Study Entry (80mg Coreg CR, 25mg Coreg IR)Maintenance Entry (80mg Coreg CR, 25mg Coreg IR)End of Study (80mg Coreg CR, 25mg Coreg IR)
Carvedilol Controlled Release8304399162716224114111
Carvedilol Immediate Release79076113162112214116121

Incidence of Hospitalizations

(NCT00323037)
Timeframe: Up to 32 weeks (titration and maintenance phases)

,
Interventionparticipants in each treatment group (Number)
Hospitalization for Heart FailureHospitalization Due to Any CauseHospitalization or Death
Carvedilol Controlled Release62929
Carvedilol Immediate Release63132

Reviews

11 reviews available for carvedilol and Disease Exacerbation

ArticleYear
What is the role, if any, for beta-blockers as initial therapy for uncomplicated hypertension?
    Current opinion in cardiology, 2009, Volume: 24, Issue:4

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzopyrans; Blood Pressure; Carbazoles; Carve

2009
β-blockers in stage B: a precursor of heart failure.
    Heart failure clinics, 2012, Volume: 8, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Bisoprolol; Carbazoles; Cardiovascular System; C

2012
Antiadrenergic therapy in the control of atrial fibrillation.
    Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10 Suppl 1

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Carbazoles; Cardi

2005
Beta blockers or angiotensin-converting-enzyme inhibitor/angiotensin receptor blocker: what should be first?
    Cardiology clinics, 2007, Volume: 25, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carbazoles; Carve

2007
Effects of beta-adrenergic blockade on survival of patients with chronic heart failure.
    The American journal of cardiology, 1997, Dec-04, Volume: 80, Issue:11A

    Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Clinical Trials as Topic; Disease Prog

1997
Carvedilol: preclinical profile and mechanisms of action in preventing the progression of congestive heart failure.
    European heart journal, 1998, Volume: 19 Suppl B

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Carbazoles; Carved

1998
Neurohormonal activation, oxygen free radicals, and apoptosis in the pathogenesis of congestive heart failure.
    Journal of cardiovascular pharmacology, 1998, Volume: 32 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antioxidants; Apoptosis; Carbazoles; Carvedilol; Disease Progression; H

1998
Progression from hypertension to heart failure. Mechanisms and management.
    Cardiology, 1999, Volume: 92 Suppl 1

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Disease Progression; Heart Failure; Humans; Hyp

1999
Beta-blockers: the new standard of therapy for mild heart failure.
    Archives of internal medicine, 2000, May-08, Volume: 160, Issue:9

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Chronic Disease; Diastole; Disease Progression;

2000
Sympathetic activation and the role of beta-blockers in chronic heart failure.
    Australian and New Zealand journal of medicine, 1999, Volume: 29, Issue:3

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Disease Progression; Heart Failure; Hemodynamic

1999
[Role of beta-blockers in the treatment of chronic heart heart failure].
    Orvosi hetilap, 2001, Sep-16, Volume: 142, Issue:37

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Controlled Clinica

2001

Trials

7 trials available for carvedilol and Disease Exacerbation

ArticleYear
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.
    Gut, 2017, Volume: 66, Issue:10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Carbazoles; Carvedilol; Disease Progression; Disease

2017
Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype.
    Molecular medicine (Cambridge, Mass.), 2002, Volume: 8, Issue:11

    Topics: Antihypertensive Agents; Atrial Natriuretic Factor; Biopsy; Calcium-Transporting ATPases; Carbazoles

2002
Symptoms in patients with heart failure are prognostic predictors: insights from COMET.
    Journal of cardiac failure, 2005, Volume: 11, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Carbazoles; Carvedilol; Disease Progression; Dou

2005
Effects of carvedilol on left ventricular diastolic function and chamber volumes in advanced heart failure.
    Minerva cardioangiologica, 2005, Volume: 53, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Diastole; Disease Progression; Double-Bli

2005
Beta-blocker therapy for cardiac dysfunction in patients with muscular dystrophy.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:8

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Carbazoles

2006
Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure. US Carvedilol Heart Failure Study Group.
    Circulation, 1996, Dec-01, Volume: 94, Issue:11

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Cardiac Output,

1996
Carvedilol treatment of kidney graft recipients with chronic rejection.
    Clinical transplantation, 1999, Volume: 13, Issue:6

    Topics: Adult; Aged; Antihypertensive Agents; Carbazoles; Carvedilol; Cholesterol, HDL; Cholesterol, LDL; Ch

1999

Other Studies

16 other studies available for carvedilol and Disease Exacerbation

ArticleYear
MitraClip or Ventricular Assist Device?
    International heart journal, 2020, Nov-28, Volume: 61, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiac Resynchronization The

2020
Digoxin Toxicity in a Neonate Caused by the Interaction with Carvedilol.
    Klinische Padiatrie, 2017, Volume: 229, Issue:2

    Topics: Adrenergic beta-Antagonists; Cardiovascular Agents; Carvedilol; Digoxin; Disease Progression; Heart

2017
The evaluation of β-adrenoceptor blocking agents in patients with COPD and congestive heart failure: a nationwide study.
    International journal of chronic obstructive pulmonary disease, 2017, Volume: 12

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol; Chi-Square

2017
Update on pharmacological advances.
    The Journal of invasive cardiology, 2004, Volume: 16 Suppl E

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Disea

2004
Attending rounds: a patient with accelerated hypertension and an atrophic kidney.
    Clinical journal of the American Society of Nephrology : CJASN, 2014, Jun-06, Volume: 9, Issue:6

    Topics: Aged; Amides; Antihypertensive Agents; Atherosclerosis; Atrophy; Blood Pressure; Carbazoles; Carvedi

2014
Pulmonary capillary hemangiomatosis: a diagnostic challenge.
    Archivos de bronconeumologia, 2015, Volume: 51, Issue:2

    Topics: Carbazoles; Carvedilol; Delayed Diagnosis; Disease Progression; Furosemide; Granuloma, Pyogenic; Hum

2015
Impact of β-blocker selectivity on long-term outcomes in congestive heart failure patients with chronic obstructive pulmonary disease.
    International journal of chronic obstructive pulmonary disease, 2015, Volume: 10

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aged, 80 and over; Bisoprolol; Carbazoles; Carvedilol

2015
Enalapril and losartan are more effective than carvedilol in preventing dilated cardiomyopathy in the Syrian cardiomyopathic hamster.
    Journal of cardiovascular pharmacology and therapeutics, 2008, Volume: 13, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2008
Lack of association between adrenergic receptor genotypes and survival in heart failure patients treated with carvedilol or metoprolol.
    Journal of the American College of Cardiology, 2008, Aug-19, Volume: 52, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Disease Progression; Female; Genotype; Ha

2008
Effect of carvedilol on pulse pressure and left ventricular hypertrophy in spontaneously hypertensive rats with adriamycin nephropathy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers; Blood Pressu

2009
Cardiac magnetic resonance imaging and management of dilated cardiomyopathy in a Duchenne muscular dystrophy manifesting carrier.
    Journal of neurology, 2009, Volume: 256, Issue:2

    Topics: Adult; Biomarkers; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Child; Creatine Kinase; Disease

2009
Which beta-blocker is most effective in heart failure?
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Clinical Tria

2010
Carvedilol attenuates the progression of alcohol fatty liver disease in rats.
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:9

    Topics: Adrenergic beta-Antagonists; Animals; Blood Vessels; Blotting, Western; Carbazoles; Carvedilol; Cent

2012
Influence of carvedilol on chronic renal failure progression in spontaneously hypertensive rats with adriamycin nephropathy.
    Clinical nephrology, 2005, Volume: 63, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antihypertensive Agents; Blood Pressure; Captopril; Carbazoles

2005
Low dose carvedilol inhibits progression of heart failure in rats with dilated cardiomyopathy.
    British journal of pharmacology, 2000, Volume: 130, Issue:7

    Topics: Animals; Body Weight; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Disease Progression; Endomyoc

2000
Influence of carvedilol on hospitalizations in heart failure: incidence, resource utilization and costs. U.S. Carvedilol Heart Failure Study Group.
    Journal of the American College of Cardiology, 2001, Volume: 37, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Chron

2001