Page last updated: 2024-10-24

carvedilol and Cruveilhier-Baumgarten Syndrome

carvedilol has been researched along with Cruveilhier-Baumgarten Syndrome in 55 studies

Cruveilhier-Baumgarten Syndrome: Liver cirrhosis with intrahepatic portal obstruction, HYPERTENSION, and patent UMBILICAL VEINS.

Research Excerpts

ExcerptRelevanceReference
" The aim of this randomized study was to evaluate and compare the effects of carvedilol and nebivolol on the hepatic venous pressure gradient (HVPG) response in the patients with liver cirrhosis."9.17Acute and 14-day hepatic venous pressure gradient response to carvedilol and nebivolol in patients with liver cirrhosis. ( Jonaitis, L; Kupčinskas, J; Kupčinskas, L; Petrenkienė, V; Pranculis, A; Silkauskaitė, V, 2013)
"In this prospective cohort study, 106 cirrhotic patients with high-risk esophageal varices in the derivation cohort received carvedilol prophylaxis, and completed paired measurements of hepatic venous pressure gradient, liver stiffness (LS), and spleen stiffness (SS) at the beginning and end of dose titration."7.91Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices. ( Ahn, DW; Baik, SK; Jung, YJ; Kim, D; Kim, HY; Kim, MY; Kim, W; So, YH; Woo, H, 2019)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."6.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Liver cirrhosis was induced in rats by carbon tetrachloride (CCl4) administration for 9 weeks; carvedilol was administered simultaneously in the experimental group."5.51Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis. ( Li, G; Li, Z; Ling, L; Meng, D; Wang, G; Zhang, C, 2019)
"Cirrhotic patients with esophageal varices were randomized to carvedilol 12."5.19Carvedilol vs. esophageal variceal band ligation in the primary prophylaxis of variceal hemorrhage: a multicentre randomized controlled trial. ( Abid, S; Azam, Z; Hamid, S; Ismail, FW; Jafri, W; Khalid, A; Munir, SM; Parkash, O; Rauf, J; Shah, HA; Subhan, A, 2014)
" The aim of this randomized study was to evaluate and compare the effects of carvedilol and nebivolol on the hepatic venous pressure gradient (HVPG) response in the patients with liver cirrhosis."5.17Acute and 14-day hepatic venous pressure gradient response to carvedilol and nebivolol in patients with liver cirrhosis. ( Jonaitis, L; Kupčinskas, J; Kupčinskas, L; Petrenkienė, V; Pranculis, A; Silkauskaitė, V, 2013)
"In this prospective cohort study, 106 cirrhotic patients with high-risk esophageal varices in the derivation cohort received carvedilol prophylaxis, and completed paired measurements of hepatic venous pressure gradient, liver stiffness (LS), and spleen stiffness (SS) at the beginning and end of dose titration."3.91Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices. ( Ahn, DW; Baik, SK; Jung, YJ; Kim, D; Kim, HY; Kim, MY; Kim, W; So, YH; Woo, H, 2019)
"BACKGROUND Carvedilol is the first-line drug for the primary prophylaxis of variceal bleeding due to portal hypertension (PHT) in liver cirrhosis."3.88Carvedilol Ameliorates Intrahepatic Angiogenesis, Sinusoidal Remodeling and Portal Pressure in Cirrhotic Rats. ( Li, G; Ling, L; Meng, D; Wang, S; Zhang, C, 2018)
" The aim of study was to assess the correlation between the therapeutic efficacy of carvedilol and markers of endothelial dysfunction and systemic inflammation in patients with liver cirrhosis and portal hypertension."3.73Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes. ( Bruha, R; Dousa, M; Jachymova, M; Kalab, M; Lenicek, M; Marecek, Z; Petrtyl, J; Svestka, T; Urbanek, P; Vitek, L; Zelenka, J, 2006)
"Portal hypertension is the primary driver of decompensation, including the development of ascites, hepatic encephalopathy and variceal haemorrhage."3.01Review article: controversies surrounding the use of carvedilol and other beta blockers in the management of portal hypertension and cirrhosis. ( Gillespie, SL; Hanrahan, TP; Hayes, PC; Majumdar, A; Rockey, DC, 2023)
"Carvedilol is a non-selective beta-blocker (NSBB) acting on hyperdynamic circulation/splanchnic vasodilation and on intrahepatic resistance."3.01Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension. ( La Mura, V; Reiberger, T; Turco, L; Vitale, G, 2023)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."2.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Carvedilol has been shown to be more effective than propranolol in decreasing portal pressure."2.77Randomized, controlled trial of carvedilol versus nadolol plus isosorbide mononitrate for the prevention of variceal rebleeding. ( Chen, WC; Lo, GH; Wang, HM; Yu, HC, 2012)
"Carvedilol is an option for primary prophylaxis in patients with high-risk esophageal varices."2.74Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed. ( Ferguson, JW; Forrest, EH; Hayes, PC; Hislop, WS; Kochar, N; Leithead, JA; McAvoy, NC; Mills, PR; Stanley, AJ; Therapondos, G; Tripathi, D, 2009)
"Carvedilol is a nonselective beta-blocker with alpha(1)-adrenergic blocking activity."2.71Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis. ( Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Yang, YY, 2004)
"Portal hypertension is the result of increased hepatic resistance and portal influx."2.71The effects of carvedilol a nonselective beta-blocker on portal hemodynamics in cirrhosis. ( Andronescu, D; Dragomir, P; Fierbinteanu-Braticevici, C; Udeanu, M, 2003)
"Short-term carvedilol administration is more powerful than propranolol in decreasing hepatic venous pressure gradient (HVPG) in cirrhotic patients, but induces arterial hypotension that may prevent its long-term use in portal hypertensive patients."2.70Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis. ( Abraldes, JG; Albillos, A; Bañares, R; Bosch, J; De Diego, A; García-Pagán, JC; Lampreave, JL; Matilla, A; Moitinho, E; Piera, C, 2002)
" Chronic administration resulted in a further fall in the hepatic venous pressure gradient from a baseline of 16."2.70Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension. ( Hayes, PC; Lui, HF; Stanley, AJ; Therapondos, G; Tripathi, D, 2002)
"Carvedilol is a relatively safe, effective portal hypotensive agent, both acutely and over 7 days, but not superior to propranolol, at least in Indians."2.70Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics. ( Biswas, PK; Das, D; De, BK; Maity, AK; Majumdar, D; Mandal, SK; Sen, S, 2002)
"Recent advances in the pharmacologic treatment of portal hypertension have mainly focused on modifying an increased intrahepatic resistance through nitric oxide and/or modulation of vasoactive substances."2.61Pharmacologic Management of Portal Hypertension. ( Bunchorntavakul, C; Reddy, KR, 2019)
"Once gastroesophageal varices have developed, non-selective beta-blockers remain the cornerstone of therapy."2.55Prevention and treatment of variceal haemorrhage in 2017. ( Berzigotti, A; Bosch, J; Brunner, F, 2017)
"Carvedilol is a nonselective beta-blocker with a mild anti-alfa-1-adrenergic activity."2.50Systematic review with meta-analysis: the haemodynamic effects of carvedilol compared with propranolol for portal hypertension in cirrhosis. ( D'Amico, G; D'Amico, M; Perricone, G; Sinagra, E; Tinè, F, 2014)
"Development of bleeding gastroesophageal varices is a serious consequence of portal hypertension secondary to cirrhosis."2.42Evaluation of carvedilol for the treatment of portal hypertension. ( Hemstreet, BA, 2004)
"Treatment of portal hypertension is evolving based on randomised controlled trials."2.42Management of portal hypertension. ( Burroughs, AK; Patch, DW; Samonakis, DN; Thalheimer, U; Triantos, CK, 2004)
"Presence and size of esophagogastric varices had an inverse relation to SDANN and SD of the NN intervals."1.91Heart rate variability is associated with disease severity and portal hypertension in cirrhosis. ( Amodio, E; Basso, MG; Cabibbo, G; Calvaruso, V; Casuccio, A; Craxì, A; Daidone, M; Di Raimondo, D; Licata, M; Miceli, G; Pennisi, G; Petta, S; Pinto, A; Pintus, C; Simone, F; Tuttolomondo, A; Velardo, M, 2023)
"Although liver cirrhosis complicated with chylothorax is rare, several case reports have shown all patients with chylothorax caused by liver cirrhosis were transudative."1.72[Transudative chylothorax complicated with liver cirrhosis due to primary biliary cholangitis:case report]. ( Higashizawa, T; Hisatake, Y; Kitagawa, K; Kondo, M; Noda, M; Okamura, Y; Sekine, C; Sunaga, S; Teramoto, K, 2022)
"Carvedilol was shown to have a positive effect on gastric varices without significant adverse effects."1.56CARVEDILOL AS PRIMARY PROPHYLAXIS FOR GASTRIC VARICEAL BLEEDING IN PORTAL HYPERTENSION MODEL IN RATS. ( Bertoldi, AS; Brighenti, LMV; Coltro, GA; Fauat, NI; Guetter, CR; Kubrusly, FB; Kubrusly, LF; Marques, CAM; Vosgerau, LM, 2020)
"Liver cirrhosis was induced in rats by carbon tetrachloride (CCl4) administration for 9 weeks; carvedilol was administered simultaneously in the experimental group."1.51Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis. ( Li, G; Li, Z; Ling, L; Meng, D; Wang, G; Zhang, C, 2019)
"Carvedilol 12."1.48Carvedilol for reducing portal pressure in primary prophylaxis of variceal bleeding: a dose-response study. ( Ferlitsch, A; Kivaranovic, D; Mandorfer, M; Paternostro, R; Peck-Radosavljevic, M; Reiberger, T; Schwarzer, R; Trauner, M, 2018)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.45)18.2507
2000's11 (20.00)29.6817
2010's30 (54.55)24.3611
2020's11 (20.00)2.80

Authors

AuthorsStudies
Jindal, A2
Sarin, SK2
Kumar, M1
Kumar, G1
Sunaga, S1
Okamura, Y1
Kondo, M1
Kitagawa, K1
Noda, M1
Hisatake, Y1
Teramoto, K1
Higashizawa, T1
Sekine, C1
Villanueva, C3
Torres, F2
Shah, HA2
Tripathi, D6
Brujats, A1
Rodrigues, SG1
Bhardwaj, A1
Azam, Z2
Hayes, PC7
Abid, S2
Alvarado, E2
Bosch, J8
Gillespie, SL1
Hanrahan, TP1
Rockey, DC1
Majumdar, A1
Miceli, G1
Calvaruso, V1
Casuccio, A1
Pennisi, G1
Licata, M1
Pintus, C1
Basso, MG1
Velardo, M1
Daidone, M1
Amodio, E1
Petta, S1
Simone, F1
Cabibbo, G1
Di Raimondo, D1
Craxì, A1
Pinto, A1
Tuttolomondo, A1
Turco, L1
Reiberger, T6
Vitale, G1
La Mura, V1
Bunchorntavakul, C1
Reddy, KR1
El Shahawy, MS1
Shady, ZM1
Gaafar, A1
Huang, X1
Fan, X1
Chen, S1
Bertoldi, AS1
Guetter, CR1
Coltro, GA1
Vosgerau, LM1
Brighenti, LMV1
Fauat, NI1
Kubrusly, FB1
Marques, CAM1
Kubrusly, LF1
Ttl Tjwa, E1
McDonald, N1
Lilburn, DML1
Lachlan, NJ1
Macnaught, G1
Patel, D1
Jayaswal, ANA1
Semple, SI1
Fallowfield, JA1
Püspök, A1
Schoder, M1
Baumann-Durchschein, F1
Bucsics, T1
Datz, C1
Dolak, W1
Ferlitsch, A4
Finkenstedt, A1
Graziadei, I1
Hametner, S1
Karnel, F1
Krones, E1
Maieron, A1
Mandorfer, M3
Peck-Radosavljevic, M3
Rainer, F1
Schwabl, P1
Stadlbauer, V1
Stauber, R1
Tilg, H1
Trauner, M2
Zoller, H1
Schöfl, R1
Fickert, P1
Baiges, A1
Hernández-Gea, V1
Sarkar, R1
Paul, R1
Roy, D1
Saha, A1
Sau, TJ1
Mondal, J1
Schwarzer, R1
Kivaranovic, D1
Paternostro, R1
Stanley, AJ3
Kim, HY1
So, YH1
Kim, W1
Ahn, DW1
Jung, YJ1
Woo, H1
Kim, D1
Kim, MY2
Baik, SK2
Ling, L2
Li, G2
Meng, D2
Wang, S1
Zhang, C2
Albillos, A2
Genescà, J1
Garcia-Pagan, JC3
Calleja, JL1
Aracil, C1
Bañares, R3
Morillas, RM1
Poca, M1
Peñas, B1
Augustin, S1
Abraldes, JG2
Wang, G1
Li, Z1
Hobolth, L2
Bendtsen, F2
Hansen, EF1
Møller, S2
Rauf, J1
Hamid, S1
Jafri, W1
Khalid, A1
Ismail, FW1
Parkash, O1
Subhan, A1
Munir, SM1
Sinagra, E1
Perricone, G1
D'Amico, M1
Tinè, F1
D'Amico, G1
Berzigotti, A2
Silkauskaitė, V1
Kupčinskas, J1
Pranculis, A1
Jonaitis, L1
Petrenkienė, V1
Kupčinskas, L1
Li, T1
Ke, W1
Sun, P1
Chen, X1
Belgaumkar, A1
Huang, Y1
Xian, W1
Li, J1
Zheng, Q1
Kim, SG1
Kim, TY1
Sohn, JH1
Um, SH1
Seo, YS1
Jang, JY1
Jeong, SW1
Lee, B1
Kim, YS1
Suk, KT1
Kim, DJ1
Brunner, F1
Steib, CJ1
Gerbes, AL1
Ferguson, JW1
Kochar, N1
Leithead, JA1
Therapondos, G2
McAvoy, NC1
Forrest, EH2
Hislop, WS1
Mills, PR1
Tsochatzis, EA1
Triantos, CK2
Burroughs, AK2
Wang, CC1
Kao, JH1
Hussain, Q1
Badruddin, AH1
Chaudhry, MA1
Ahmad, F1
Abbasi, A1
Payer, BA1
Pinter, M1
Homoncik, M1
Grønbæk, H1
Roelsgaard, K1
Feldager Hansen, E1
Lo, GH1
Chen, WC1
Wang, HM1
Yu, HC1
Moitinho, E2
Matilla, A1
Lampreave, JL1
Piera, C1
De Diego, A2
Hemstreet, BA1
Lin, HC1
Yang, YY1
Hou, MC1
Huang, YT1
Lee, FY1
Lee, SD1
Fierbinteanu-Braticevici, C1
Udeanu, M1
Dragomir, P1
Andronescu, D1
Samonakis, DN1
Thalheimer, U1
Patch, DW1
Bruha, R1
Vitek, L1
Petrtyl, J1
Lenicek, M1
Urbanek, P1
Zelenka, J1
Jachymova, M1
Svestka, T1
Kalab, M1
Dousa, M1
Marecek, Z1
Bouchier, IA1
Sekiyama, T1
Komeichi, H1
Nagano, T1
Ohsuga, M1
Terada, H1
Katsuta, Y1
Satomura, K1
Aramaki, T1
Piqueras, B1
Casado, M1
Wong, F1
Blendis, L1
Lui, HF1
De, BK1
Das, D1
Sen, S1
Biswas, PK1
Mandal, SK1
Majumdar, D1
Maity, AK1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Multicenter Cohort Study on the Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in Cirrhosis[NCT04932200]608 participants (Anticipated)Observational2021-06-15Not yet recruiting
Timing of Endoscopic Intervention in Patients With Cirrhosis With Acute Variceal Upper Gastrointestinal Hemorrhage (TEACH Trial): a Randomized Clinical Trial[NCT04786743]400 participants (Anticipated)Interventional2021-04-20Recruiting
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis: a Prospective Cohort Study[NCT04543643]Phase 3288 participants (Anticipated)Interventional2021-11-01Not yet recruiting
Prospective Cohort Study to Evaluate Long-term Outcomes in Patients With Liver Cirrhosis of Boramae Hospital[NCT01943318]500 participants (Actual)Observational [Patient Registry]2013-01-31Completed
Spleen Stiffness Combined With Liver Stiffness Measured by Two-dimensional Shear Wave Elastography for the Screening of High-risk Varices in Patients With Compensated Advanced Chronic Liver Disease (CHESS2004)[NCT04546360]300 participants (Anticipated)Observational [Patient Registry]2020-09-08Recruiting
A Novel Algorithm to Stratify Clinical Decompensation Risk in Patients With Compensated Advanced Chronic Liver Disease (CHESS2108)[NCT05100485]1,000 participants (Actual)Observational2022-01-01Completed
Multicenter, Randomized, Double-blind, Placebo-controlled Study on the Effectiveness of Treatment With Beta-blockers to Prevent Decompensation of Cirrhosis With Portal Hypertension[NCT01059396]Phase 4201 participants (Actual)Interventional2010-01-28Completed
CHESS-SAVE Score to Stratify Decompensation Risk in Compensated Advanced Chronic Liver Disease: an International Multicenter Study (CHESS2102)[NCT04975477]1,000 participants (Anticipated)Observational2021-07-16Not yet recruiting
Hemodynamic Effect of the Combination of Simvastatin With Non-cardioselective Beta Blockers in Patients With Cirrhosis and Clinically Significant Portal Hypertension[NCT01282385]Phase 460 participants (Anticipated)Interventional2011-04-30Not yet recruiting
Danish Carvedilol Study in Portal Hypertension. Carvedilol in the Prevention of Bleeding in Portal Hypertension and Esophageal Varices[NCT00493480]Phase 340 participants (Anticipated)Interventional2003-09-30Completed
Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252]Phase 119 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for carvedilol and Cruveilhier-Baumgarten Syndrome

ArticleYear
Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis.
    Journal of hepatology, 2022, Volume: 77, Issue:4

    Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Humans; Hypertensi

2022
Review article: controversies surrounding the use of carvedilol and other beta blockers in the management of portal hypertension and cirrhosis.
    Alimentary pharmacology & therapeutics, 2023, Volume: 57, Issue:5

    Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal H

2023
Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:6

    Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal H

2023
Pharmacologic Management of Portal Hypertension.
    Clinics in liver disease, 2019, Volume: 23, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anticoagulants; Antihypertensi

2019
Pharmacologic prevention of variceal bleeding and rebleeding.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Atorvastatin; Carbazoles; Carvedilol; Esophageal and Gastric Varices; G

2018
Systematic review with meta-analysis: the haemodynamic effects of carvedilol compared with propranolol for portal hypertension in cirrhosis.
    Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:6

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Hemodynamics; Hepatic Veins; Humans; Hypertensi

2014
Pharmacologic management of portal hypertension.
    Clinics in liver disease, 2014, Volume: 18, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Anti-

2014
Carvedilol for portal hypertension in cirrhosis: systematic review with meta-analysis.
    BMJ open, 2016, 05-04, Volume: 6, Issue:5

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Esophageal and Ga

2016
Beta blockers and cirrhosis, 2016.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Ascites; Carbazoles; Carvedilol; Esophageal and Ga

2017
Prevention and treatment of variceal haemorrhage in 2017.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37 Suppl 1

    Topics: Adrenergic beta-Antagonists; Anti-Bacterial Agents; Balloon Occlusion; Carbazoles; Carvedilol; Endos

2017
The role of carvedilol in the management of portal hypertension.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:8

    Topics: Antihypertensive Agents; Ascites; Benzopyrans; Carbazoles; Carvedilol; Drug Therapy, Combination; Et

2010
Evaluation of carvedilol for the treatment of portal hypertension.
    Pharmacotherapy, 2004, Volume: 24, Issue:1

    Topics: Adrenergic Antagonists; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Fibrosis; Humans; Hy

2004
Management of portal hypertension.
    Postgraduate medical journal, 2004, Volume: 80, Issue:949

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Humans; Hyperte

2004

Trials

18 trials available for carvedilol and Cruveilhier-Baumgarten Syndrome

ArticleYear
Assessment of Haemodynamic Response to Nonselective Beta-Blockers in Portal Hypertension by Phase-Contrast Magnetic Resonance Angiography.
    BioMed research international, 2017, Volume: 2017

    Topics: Adrenergic beta-Antagonists; Aged; Aorta, Abdominal; Carbazoles; Carvedilol; Contrast Media; Female;

2017
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
Effects of carvedilol and propranolol on circulatory regulation and oxygenation in cirrhosis: a randomised study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2014, Volume: 46, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Arteries; Blood Pressure; Bloo

2014
Carvedilol vs. esophageal variceal band ligation in the primary prophylaxis of variceal hemorrhage: a multicentre randomized controlled trial.
    Journal of hepatology, 2014, Volume: 60, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol;

2014
Acute and 14-day hepatic venous pressure gradient response to carvedilol and nebivolol in patients with liver cirrhosis.
    Medicina (Kaunas, Lithuania), 2013, Volume: 49, Issue:11

    Topics: Aged; Antihypertensive Agents; Benzopyrans; Carbazoles; Carvedilol; Ethanolamines; Female; Humans; H

2013
A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:11

    Topics: Adult; Antihypertensive Agents; Ascites; Carbazoles; Carvedilol; End Stage Liver Disease; Esophageal

2016
Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Fe

2009
Gastrointestinal bleeding: Carvedilol-the best beta-blocker for primary prophylaxis?
    Nature reviews. Gastroenterology & hepatology, 2009, Volume: 6, Issue:12

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Endoscopy; Esophageal and Gastric Varices; Gast

2009
Effect of carvedilol on portal pressure estimated by hepatic vein Doppler ultrasound waveform and damping index in cirrhotic patients.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2010, Volume: 20, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Flow Velocity; Carbazoles; Carvedilol; Female; Hepat

2010
Carvedilol or propranolol in portal hypertension? A randomized comparison.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Double-Blind Method; Fema

2012
Randomized, controlled trial of carvedilol versus nadolol plus isosorbide mononitrate for the prevention of variceal rebleeding.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:11

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Chi-Square Distribution; Dru

2012
Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:6

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hyperten

2002
Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:10

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hyperten

2004
The effects of carvedilol a nonselective beta-blocker on portal hemodynamics in cirrhosis.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2003, Volume: 41, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Female; Hemodynamics; Humans; Hype

2003
Effects of the alpha-/beta-blocking agent carvedilol on hepatic and systemic hemodynamics in patients with cirrhosis and portal hypertension.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles;

1997
Carvedilol, a new nonselective beta-blocker with intrinsic anti- Alpha1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure;

1999
Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:3

    Topics: Carbazoles; Carvedilol; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypertension, Po

2002
Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbazole

2002

Other Studies

24 other studies available for carvedilol and Cruveilhier-Baumgarten Syndrome

ArticleYear
Clinical Outcomes in Patients with Advanced Chronic Liver Disease and Hepatic Venous Pressure Gradient ≤ 10 mm Hg.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:11

    Topics: Carvedilol; Elasticity Imaging Techniques; Humans; Hypertension, Portal; Liver Cirrhosis; Portal Pre

2022
[Transudative chylothorax complicated with liver cirrhosis due to primary biliary cholangitis:case report].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2022, Volume: 119, Issue:4

    Topics: Aged; Bisoprolol; Carvedilol; Chylothorax; Dyspnea; Female; Heart Failure; Humans; Hypertension, Por

2022
Heart rate variability is associated with disease severity and portal hypertension in cirrhosis.
    Hepatology communications, 2023, 03-01, Volume: 7, Issue:3

    Topics: Ascites; Carvedilol; Cross-Sectional Studies; Esophageal and Gastric Varices; Heart Rate; Humans; Hy

2023
Carvedilol, probably the β-blocker of choice for everyone with cirrhosis and portal hypertension: But not so fast!
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:6

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Humans; Hypertension, Portal; Liver Cirrhosis;

2023
The Efficacy of Argon Plasma Coagulation versus Carvedilol for Treatment of Portal Hypertensive Gastropathy.
    Digestion, 2020, Volume: 101, Issue:6

    Topics: Argon Plasma Coagulation; Carvedilol; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Sto

2020
Individualized Treatment of Gastric Varices in Cirrhotic Portal Hypertension.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:13

    Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Porta

2019
KASL clinical practice guidelines for liver cirrhosis: Varices, hepatic encephalopathy, and related complications.
    Clinical and molecular hepatology, 2020, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Ammonia; Anti-Bacterial Agents; Carvedilol; Disaccharides; Endoscopy, G

2020
CARVEDILOL AS PRIMARY PROPHYLAXIS FOR GASTRIC VARICEAL BLEEDING IN PORTAL HYPERTENSION MODEL IN RATS.
    Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2020, Volume: 33, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carvedilol; Esophageal and Gastric Va

2020
Editorial: Beta blockers and cirrhosis-more than just portal hypertension?
    Alimentary pharmacology & therapeutics, 2021, Volume: 53, Issue:5

    Topics: Adrenergic beta-Antagonists; Carvedilol; Follow-Up Studies; Humans; Hypertension, Portal; Liver Cirr

2021
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
A Patient with Dilated Cardiomyopathy and Portal Hypertension: Which Beta-Blocker to Use?
    The Journal of the Association of Physicians of India, 2017, Volume: 65, Issue:9

    Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Clinical Decision-Maki

2017
Carvedilol for reducing portal pressure in primary prophylaxis of variceal bleeding: a dose-response study.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:8

    Topics: Antihypertensive Agents; Carvedilol; Dose-Response Relationship, Drug; Esophageal and Gastric Varice

2018
Editorial: optimal dose of carvedilol in portal hypertension…nearly there. Authors' reply.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:9

    Topics: Carvedilol; Humans; Hypertension, Portal; Propanolamines

2018
Editorial: optimal dose of carvedilol in portal hypertension…nearly there.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:9

    Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Porta

2018
Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices.
    Journal of hepatology, 2019, Volume: 70, Issue:3

    Topics: Adrenergic beta-Antagonists; Carvedilol; Chemoprevention; Clinical Decision Rules; Elasticity Imagin

2019
Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices.
    Journal of hepatology, 2019, Volume: 70, Issue:3

    Topics: Adrenergic beta-Antagonists; Carvedilol; Chemoprevention; Clinical Decision Rules; Elasticity Imagin

2019
Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices.
    Journal of hepatology, 2019, Volume: 70, Issue:3

    Topics: Adrenergic beta-Antagonists; Carvedilol; Chemoprevention; Clinical Decision Rules; Elasticity Imagin

2019
Non-invasive response prediction in prophylactic carvedilol therapy for cirrhotic patients with esophageal varices.
    Journal of hepatology, 2019, Volume: 70, Issue:3

    Topics: Adrenergic beta-Antagonists; Carvedilol; Chemoprevention; Clinical Decision Rules; Elasticity Imagin

2019
Carvedilol Ameliorates Intrahepatic Angiogenesis, Sinusoidal Remodeling and Portal Pressure in Cirrhotic Rats.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Nov-18, Volume: 24

    Topics: Angiogenesis Inducing Agents; Animals; Capillaries; Carvedilol; Endothelial Cells; Fibronectins; Hum

2018
Carvedilol improves liver cirrhosis in rats by inhibiting hepatic stellate cell activation, proliferation, invasion and collagen synthesis.
    Molecular medicine reports, 2019, Volume: 20, Issue:2

    Topics: Administration, Oral; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carb

2019
Secondary prophylaxis for variceal bleeding: carvedilol vs. propranolol.
    Hepatology international, 2017, Volume: 11, Issue:2

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Drug Monitoring; Esophageal and

2017
Carvedilol versus variceal band ligation for prevention of the first variceal bleed.
    Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:2

    Topics: Carbazoles; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hyperte

2010
Carvedilol for portal hypertension in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:6

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Humans; Hypertension, Portal; Liver Cirrhosis; Male

2010
Non-selective β-blockers improve the correlation of liver stiffness and portal pressure in advanced cirrhosis.
    Journal of gastroenterology, 2012, Volume: 47, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Elasticity; Elasticity Imaging Technique

2012
Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:12

    Topics: Adrenergic beta-Antagonists; Biomarkers; Carbazoles; Carvedilol; E-Selectin; Endothelium, Vascular;

2006
Acute haemodynamic changes after oral carvedilol, a vasodilating beta-blocker, in patients with cirrhosis.
    Journal of hepatology, 1996, Volume: 25, Issue:6

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Azygos Vein; Blood Flow Velocity; Blood Pressure;

1996
An advance in the treatment of portal hypertension?
    Gastroenterology, 2000, Volume: 118, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Humans; Hypertens

2000