Page last updated: 2024-10-24

carvedilol and Cardiomyopathies

carvedilol has been researched along with Cardiomyopathies in 45 studies

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Relative effectiveness of carvedilol and metoprolol succinate has never been compared in patients with heart failure (HF)."7.78Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis. ( Aggarwal, V; Shore, S; Zolty, R, 2012)
"Carvedilol therapy reduces mortality from sudden cardiac death and progressive pump failure in congestive heart failure (CHF)."7.71The effects of chronic carvedilol therapy on QT dispersion in patients with congestive heart failure. ( Oto, A; Sade, E; Tokgozoglu, L; Yildirir, A, 2001)
"Carvedilol is a non-selective beta-blocker with alpha-receptor blockade and antioxidant properties."5.32Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure. ( Doye, AA; Gwathmey, JK; Hajjar, RJ; Jabbour, G; Laste, N; Lebeche, D; Lee, MX; Okafor, CC; Perreault-Micale, C; Skiroman, K, 2003)
"Herein two breast cancer cell lines, SKBr3 and BT474, overexpressing human epithelial receptor 2 (HER2), the target of the humanised antibody trastuzumab, were treated with a range of concentrations (20-2000 nM) of doxorubicin with and without trastuzumab in the presence of clinically relevant doses of the ACE inhibitor enalapril, the beta-blocker carvedilol, metformin or dexrazoxane, and cell survival determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay."3.83Effects of Administered Cardioprotective Drugs on Treatment Response of Breast Cancer Cells. ( Akabuogu, EU; Phyu, SM; Smith, TA, 2016)
"Relative effectiveness of carvedilol and metoprolol succinate has never been compared in patients with heart failure (HF)."3.78Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis. ( Aggarwal, V; Shore, S; Zolty, R, 2012)
" In this report, we describe 5 cases of severe chronic heart failure due to ACM effectively treated with the beta-blocker, carvedilol."3.72Five cases of anthracycline-induced cardiomyopathy effectively treated with carvedilol. ( Iwato, K; Kaseda, S; Kyo, T; Mukai, N; Mukai, Y; Nakaike, R; Yoshida, T, 2004)
"Carvedilol therapy reduces mortality from sudden cardiac death and progressive pump failure in congestive heart failure (CHF)."3.71The effects of chronic carvedilol therapy on QT dispersion in patients with congestive heart failure. ( Oto, A; Sade, E; Tokgozoglu, L; Yildirir, A, 2001)
"Carvedilol has established its evidence to improve prognosis and facilitate left ventricular reverse remodeling (LVRR) in heart failure patients with reduced left ventricular ejection fraction (LVEF), and many studies have supported its dose-dependency."2.82High Dose β-Blocker Therapy Triggers Additional Reverse Remodeling in Patients With Idiopathic Non-Ischemic Cardiomyopathy. ( Imamura, T; Kato, NP; Kinugawa, K; Komuro, I; Nitta, D, 2016)
" The two referred examples result in important take-home messages: a) drug-induced cardiac mitochondrial dysfunction is an important contributor for drug-associated organ failure, b) protection of mitochondrial function is involved in the beneficial impact of some clinically-used drugs and c) a more accurate prediction of toxic vs."2.47Drug-induced cardiac mitochondrial toxicity and protection: from doxorubicin to carvedilol. ( Carvalho, FS; Diogo, CV; Monteiro, P; Oliveira, PJ; Pereira, GC; Silva, AM, 2011)
" To tackle this issue, we established embryonic zebrafish models of doxorubicin-, adrenaline- and terfenadine-induced cardiotoxicity with unified dosing regimen which eventually enabled head-to-head comparison of the drugs."1.72Pharmacological assessment of zebrafish-based cardiotoxicity models. ( Maciag, M; Mierzejewska, M; Plazinska, A; Wnorowski, A, 2022)
"However, she experienced recurrence with positive T790 M, and osimertinib (80 mg/day) was administered as the 2nd line therapy."1.56Osimertinib induced cardiomyopathy: A case report. ( Ishikawa, K; Kagamu, H; Kaira, K; Shinomiya, S; Yamaguchi, O, 2020)
"We here report a HF patient with left bundle branch block due to nonischemic cardiomyopathy who did not respond to 20 mg/day of carvedilol in terms of LVRR."1.42Reverse Remodeling Achieved by Combination Therapy With High-Dose Beta Blocker and Cardiac Resynchronization. ( Imamura, T; Kinugawa, K; Muraoka, H, 2015)
"Carvedilol is a non-selective beta-blocker with alpha-receptor blockade and antioxidant properties."1.32Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure. ( Doye, AA; Gwathmey, JK; Hajjar, RJ; Jabbour, G; Laste, N; Lebeche, D; Lee, MX; Okafor, CC; Perreault-Micale, C; Skiroman, K, 2003)
"Patients with Becker muscular dystrophy-related cardiomyopathy typically survive into their 30s, when they succumb to complications of cardiomyopathy or receive heart transplants."1.31Becker muscular dystrophy-related cardiomyopathy: a favorable response to medical therapy. ( Doing, AH; Renlund, DG; Smith, RA, 2002)
"Carvedilol (CAR) is a vasodilating beta-blocker which also has antioxidant properties."1.30Protective effects of carvedilol against doxorubicin-induced cardiomyopathy in rats. ( Hayakawa, T; Matsui, H; Morishima, I; Numaguchi, Y; Okumura, K; Toki, Y, 1999)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.22)18.7374
1990's1 (2.22)18.2507
2000's21 (46.67)29.6817
2010's16 (35.56)24.3611
2020's6 (13.33)2.80

Authors

AuthorsStudies
Maciag, M1
Wnorowski, A1
Mierzejewska, M1
Plazinska, A1
Imamura, T3
Izumida, T1
Hori, M1
Tanaka, S1
Kinugawa, K3
Kadoya, T1
Sakakibara, A1
Kitayama, K1
Yamada, Y1
Higuchi, S1
Kawakita, R1
Kawasaki, Y1
Fujino, M1
Murakami, Y1
Shimura, M1
Murayama, K1
Ohtake, A1
Okazaki, Y1
Koga, Y1
Yorifuji, T1
Alanazi, A1
Fadda, L1
Alhusaini, A1
Ahmad, R1
Syed, MP1
Doshi, A1
Pandey, D1
Kate, Y1
Harizi, R1
Beiranvand, E1
Torkashvand, F1
Ostad, SN1
Mirzaie, M1
Ardakani, EM1
Zandi, F1
Sardari, S1
Salekdeh, GH1
Shokrgozar, MA1
Vaziri, B1
Shinomiya, S1
Kaira, K1
Yamaguchi, O1
Ishikawa, K1
Kagamu, H1
Jhorawat, R1
Kumari, S1
Varma, SC1
Rohit, MK1
Narula, N1
Suri, V1
Malhotra, P1
Jain, S1
Kida, K1
Yoneyama, K1
Kobayashi, Y1
Takano, M1
Akashi, YJ1
Miyake, F1
Abu-Elsaad, NM1
Abd Elhameed, AG1
El-Karef, A1
Ibrahim, TM1
Muraoka, H1
Teoh, JP1
Park, KM1
Broskova, Z1
Jimenez, FR1
Bayoumi, AS1
Archer, K1
Su, H1
Johnson, J1
Weintraub, NL1
Tang, Y1
Kim, IM1
Chen, YL2
Chung, SY1
Chai, HT1
Chen, CH1
Liu, CF1
Huang, TH1
Zhen, YY1
Sung, PH1
Sun, CK1
Chua, S1
Lu, HI1
Lee, FY1
Sheu, JJ1
Yip, HK1
Smith, TA1
Phyu, SM1
Akabuogu, EU1
Nitta, D1
Kato, NP1
Komuro, I2
Wang, K1
Lu, D1
Zhang, B1
Wang, S1
Liu, Q1
Zhang, Q1
Geng, J1
Shan, Q1
de Groote, P1
Lamblin, N1
Mouquet, F1
Bauters, C1
Auerbach, SR1
Richmond, ME1
Lamour, JM1
Blume, ED1
Addonizio, LJ1
Shaddy, RE1
Mahony, L1
Pahl, E1
Hsu, DT1
Mah, D1
Wang, A1
Wu, A1
Alexander, ME1
Walsh, EP1
Pereira, GC1
Silva, AM1
Diogo, CV1
Carvalho, FS1
Monteiro, P2
Oliveira, PJ3
He, L1
Xiao, J1
Fu, H1
Du, G1
Xiao, X1
Zhang, C1
Gu, Y1
Ma, Y1
Elnakish, MT1
Hassona, MD1
Alhaj, MA1
Moldovan, L1
Janssen, PM1
Khan, M1
Hassanain, HH1
Shore, S1
Aggarwal, V1
Zolty, R1
Takano, H1
Harada, T1
Ohtaki, E2
Kitahara, K2
Sumiyoshi, T2
Hosoda, S2
Santos, DL1
Moreno, AJ3
Leino, RL2
Froberg, MK2
Wallace, KB2
Takeda, N1
Misu, K1
Asano, R1
Tobaru, T1
Nagayama, M1
Umemura, J1
Okafor, CC1
Perreault-Micale, C1
Hajjar, RJ1
Lebeche, D1
Skiroman, K1
Jabbour, G1
Doye, AA1
Lee, MX1
Laste, N1
Gwathmey, JK1
Armstrong, SC1
Bjork, JA1
Santos, MS1
Mukai, Y1
Yoshida, T1
Nakaike, R1
Mukai, N1
Iwato, K1
Kyo, T1
Kaseda, S1
Meyers, DE1
Maddicks-Law, J1
Seaton, DM1
Galbraith, AJ1
Cuneo, RC1
Gonçalves, L1
Providencia, LA1
Bozić, I1
Fabijanić, D1
Carević, V1
Polić, S1
Kalay, N1
Basar, E1
Ozdogru, I1
Er, O1
Cetinkaya, Y1
Dogan, A1
Inanc, T1
Oguzhan, A1
Eryol, NK1
Topsakal, R1
Ergin, A1
Florenzano, F1
Salman, P1
Cruz, N1
Arocho, L1
Rosario, L1
Crespo, MJ1
Nakanishi, M1
Harada, M1
Tadamura, E1
Kotani, H1
Kawakami, R1
Kuwahara, K1
Nakagawa, Y1
Usami, S1
Kinoshita, H1
Fujiwara, M1
Hosoda, K1
Ueshima, K1
Nakao, K1
Matsui, H1
Morishima, I1
Numaguchi, Y1
Toki, Y1
Okumura, K1
Hayakawa, T1
Noori, A1
Lindenfeld, J1
Wolfel, E1
Ferguson, D1
Bristow, MR1
Lowes, BD1
Witte, K1
Thackray, S1
Clark, AL1
Cooklin, M1
Cleland, JG1
Yildirir, A1
Sade, E1
Tokgozoglu, L1
Oto, A1
Doing, AH1
Renlund, DG1
Smith, RA1
Kaski, JC1
Rodriguez-Plaza, L1
Brown, J1
Maseri, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Spironolactone in the Prevention of Anthracycline-induced Cardiotoxicity: a Randomized Clinical Trial (SPIROTOX Trial)[NCT06005259]Phase 4264 participants (Anticipated)Interventional2023-10-01Not yet recruiting
Evaluation of Empagliflozin Effect Against Doxorubicin Induced Cardiomyopathy[NCT06103279]Phase 2/Phase 340 participants (Anticipated)Interventional2023-11-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for carvedilol and Cardiomyopathies

ArticleYear
Drug-induced cardiac mitochondrial toxicity and protection: from doxorubicin to carvedilol.
    Current pharmaceutical design, 2011, Volume: 17, Issue:20

    Topics: Adrenergic beta-Antagonists; Antibiotics, Antineoplastic; Carbazoles; Cardiomyopathies; Cardiotonic

2011
Are the antioxidant properties of carvedilol important for the protection of cardiac mitochondria?
    Current vascular pharmacology, 2005, Volume: 3, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Carbazoles; Cardiomyopathies; Carvedilol; Humans

2005
Echocardiography in the diagnosis and management of isolated left ventricular noncompaction: case reports and review of the literature.
    Journal of clinical ultrasound : JCU, 2006, Volume: 34, Issue:8

    Topics: Anticoagulants; Carbazoles; Cardiomyopathies; Carvedilol; Diagnosis, Differential; Echocardiography;

2006

Trials

4 trials available for carvedilol and Cardiomyopathies

ArticleYear
High Dose β-Blocker Therapy Triggers Additional Reverse Remodeling in Patients With Idiopathic Non-Ischemic Cardiomyopathy.
    International heart journal, 2016, Dec-02, Volume: 57, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Cardiomyopathies; Carvedilol; Dose-R

2016
Protective effects of carvedilol against anthracycline-induced cardiomyopathy.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anthracyclines; Antibiotics, Antin

2006
Protective effects of carvedilol against anthracycline-induced cardiomyopathy.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anthracyclines; Antibiotics, Antin

2006
Protective effects of carvedilol against anthracycline-induced cardiomyopathy.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anthracyclines; Antibiotics, Antin

2006
Protective effects of carvedilol against anthracycline-induced cardiomyopathy.
    Journal of the American College of Cardiology, 2006, Dec-05, Volume: 48, Issue:11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anthracyclines; Antibiotics, Antin

2006
[Efficiency of taliton in treatment of ischemic cardiomyopathy].
    Georgian medical news, 2007, Issue:153

    Topics: Adult; Aged; Antihypertensive Agents; Carbazoles; Cardiomyopathies; Carvedilol; Humans; Male; Middle

2007
Efficacy of carvedilol (BM 14,190), a new beta-blocking drug with vasodilating properties, in exercise-induced ischemia.
    The American journal of cardiology, 1985, Jul-01, Volume: 56, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Cardiomyopathies; Carvedilol;

1985

Other Studies

38 other studies available for carvedilol and Cardiomyopathies

ArticleYear
Pharmacological assessment of zebrafish-based cardiotoxicity models.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 148

    Topics: Animals; Cardiomyopathies; Cardiotoxicity; Carvedilol; Doxorubicin; Zebrafish

2022
Combination therapy using tafamidis and neurohormonal blockers for cardiac amyloidosis and a reduced ejection fraction: a case report.
    The Journal of international medical research, 2022, Volume: 50, Issue:7

    Topics: Aged; Amyloidosis; Benzoxazoles; Cardiomyopathies; Carvedilol; Humans; Male; Stroke Volume; Ventricu

2022
Successful treatment of infantile-onset ACAD9-related cardiomyopathy with a combination of sodium pyruvate, beta-blocker, and coenzyme Q10.
    Journal of pediatric endocrinology & metabolism : JPEM, 2019, Oct-25, Volume: 32, Issue:10

    Topics: Acidosis; Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adrenergic beta-Antagonists; Amino Acid M

2019
Antioxidant, antiapoptotic, and antifibrotic effects of the combination of liposomal resveratrol and carvedilol against doxorubicin-induced cardiomyopathy in rats.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cardiomyopathies; Cardiotoxicity; Car

2020
A rare case of biventricular non-compaction.
    BMJ case reports, 2020, May-13, Volume: 13, Issue:5

    Topics: Cardiomyopathies; Carvedilol; Coronary Artery Disease; Dyspnea; Furosemide; Heart Failure; Heart Ven

2020
Proteomics Analysis of Trastuzumab Toxicity in the H9c2 Cardiomyoblast Cell Line and its Inhibition by Carvedilol.
    Current pharmaceutical biotechnology, 2020, Volume: 21, Issue:13

    Topics: Adrenergic beta-Antagonists; Antineoplastic Agents, Immunological; Breast Neoplasms; Cardiomyopathie

2020
Osimertinib induced cardiomyopathy: A case report.
    Medicine, 2020, Sep-25, Volume: 99, Issue:39

    Topics: Acrylamides; Adenocarcinoma of Lung; Adrenergic beta-Antagonists; Afatinib; Aged; Angiotensin-Conver

2020
Preventive role of carvedilol in adriamycin-induced cardiomyopathy.
    The Indian journal of medical research, 2016, Volume: 144, Issue:5

    Topics: Aged; Carbazoles; Cardiomyopathies; Carvedilol; Doxorubicin; Echocardiography; Female; Heart Failure

2016
Late gadolinium enhancement on cardiac magnetic resonance images predicts reverse remodeling in patients with nonischemic cardiomyopathy treated with carvedilol.
    International journal of cardiology, 2013, Sep-30, Volume: 168, Issue:2

    Topics: Adult; Aged; Carbazoles; Cardiomyopathies; Carvedilol; Female; Gadolinium; Heart Failure; Humans; Ma

2013
Yogurt Containing the Probacteria Lactobacillus acidophilus Combined with Natural Antioxidants Mitigates Doxorubicin-Induced Cardiomyopathy in Rats.
    Journal of medicinal food, 2015, Volume: 18, Issue:9

    Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Carbazoles; Car

2015
Reverse Remodeling Achieved by Combination Therapy With High-Dose Beta Blocker and Cardiac Resynchronization.
    International heart journal, 2015, Volume: 56, Issue:4

    Topics: Adrenergic beta-Antagonists; Bundle-Branch Block; Carbazoles; Cardiac Resynchronization Therapy; Car

2015
Identification of gene signatures regulated by carvedilol in mouse heart.
    Physiological genomics, 2015, Volume: 47, Issue:9

    Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiomyopathies; Carvedilol; Gene Expression Regu

2015
Early Administration of Carvedilol Protected against Doxorubicin-Induced Cardiomyopathy.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 355, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Antibiotics, Antineoplastic; Biomarkers; Carbazoles; Cardiomyo

2015
Effects of Administered Cardioprotective Drugs on Treatment Response of Breast Cancer Cells.
    Anticancer research, 2016, Volume: 36, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Combined Chemo

2016
Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:3-4

    Topics: Alanine Transaminase; Angiotensin II; Animals; Aorta; Blood Pressure; Carbazoles; Cardiomegaly; Card

2016
No gender survival difference in a population of patients with chronic heart failure related to left ventricular systolic dysfunction and receiving optimal medical therapy.
    Archives of cardiovascular diseases, 2008, Volume: 101, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiomyopathies;

2008
BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol Trial.
    Circulation. Heart failure, 2010, Volume: 3, Issue:5

    Topics: Adrenergic beta-Antagonists; Age Factors; Biomarkers; Carbazoles; Cardiomyopathies; Carvedilol; Chi-

2010
Marked QT prolongation and ventricular tachycardia of a transient nature in young children with cardiomyopathy.
    Pacing and clinical electrophysiology : PACE, 2012, Volume: 35, Issue:8

    Topics: Carbazoles; Cardiomyopathies; Cardiotonic Agents; Carvedilol; Child; Electrocardiography; Humans; In

2012
Effect of oxidative stress on ventricular arrhythmia in rabbits with adriamycin-induced cardiomyopathy.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2012, Volume: 32, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Antibiotics, Antineoplastic; Carbazoles; Cardiomyopathies; Carvedil

2012
Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Apoptosis; Blotting, Western; Carbazoles; Cardiomegaly; Cardiomyopathies; Carvedilol; Echoc

2012
Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis.
    Journal of cardiac failure, 2012, Volume: 18, Issue:12

    Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathies; Carvedilol; Cohort Studies; Delayed-Actio

2012
Beta-blockers have beneficial effects even on unclassified cardiomyopathy such as isolated ventricular noncompaction.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:8

    Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathies; Carvedilol; Humans; Propanolamines

2002
Carvedilol-induced changes in cardiac diastolic performance in a patient with isolated noncompaction of the myocardium.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Cardiomyopathies; Carvedilol; Diastole; Echocardiogr

2002
Carvedilol protects against doxorubicin-induced mitochondrial cardiomyopathy.
    Toxicology and applied pharmacology, 2002, Dec-15, Volume: 185, Issue:3

    Topics: Adrenergic beta-Antagonists; Algorithms; Animals; Antibiotics, Antineoplastic; Biological Transport;

2002
Normalization of left ventricular parameters following combined pimobendan and carvedilol treatment in a case of unclassified cardiomyopathy with longstanding refractory status.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:12

    Topics: Carbazoles; Cardiomyopathies; Cardiovascular Agents; Carvedilol; Heart Failure; Humans; Male; Middle

2002
Chronic treatment with carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure.
    BMC physiology, 2003, Jul-21, Volume: 3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Apoptosis; Carbazo

2003
Anti-oxidants and apoptosis: attenuation of doxorubicin induced cardiomyopathy by carvedilol.
    Journal of molecular and cellular cardiology, 2004, Volume: 37, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Carbazoles; Cardiomyopathies; Carvedi

2004
Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity.
    Toxicology and applied pharmacology, 2004, Oct-15, Volume: 200, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antibiotics, Antineoplastic; Antioxidants; Calcium; Carbazoles

2004
Five cases of anthracycline-induced cardiomyopathy effectively treated with carvedilol.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Anthracyclines; Carbazoles; Cardiomyopathies; Carvedilol; Echoca

2004
The role of growth hormone replacement in a growth hormone deficient patient with underlying cardiomyopathy and severe congestive heart failure.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2005, Volume: 24, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Carbazoles

2005
Carvedilol for anthracycline cardiomyopathy prevention.
    Journal of the American College of Cardiology, 2007, May-29, Volume: 49, Issue:21

    Topics: Anthracyclines; Carbazoles; Cardiomyopathies; Carvedilol; Dose-Response Relationship, Drug; Humans;

2007
Chronic administration of carvedilol improves cardiac function in 6-month-old Syrian cardiomyopathic hamsters.
    Pharmacology, 2007, Volume: 80, Issue:2-3

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Carbazoles; Cardiac Output; Cardiomyopathies;

2007
Images in cardiovascular medicine. Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance.
    Circulation, 2007, Jul-10, Volume: 116, Issue:2

    Topics: Aged; Biopsy; Carbazoles; Cardiomyopathies; Carvedilol; Coenzymes; Coronary Angiography; Enalapril;

2007
Protective effects of carvedilol against doxorubicin-induced cardiomyopathy in rats.
    Life sciences, 1999, Volume: 65, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Blood Pressure; Carbazoles; Cardiomyopathies; Ca

1999
Beta-blockade in adriamycin-induced cardiomyopathy.
    Journal of cardiac failure, 2000, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antineoplastic Agents; Carbazoles; Cardiomyopathies; Cardi

2000
Clinical trials update: IMPROVEMENT-HF, COPERNICUS, MUSTIC, ASPECT-II, APRICOT and HEART.
    European journal of heart failure, 2000, Volume: 2, Issue:4

    Topics: Adrenergic beta-Antagonists; Anticoagulants; Carbazoles; Cardiomyopathies; Carvedilol; Clinical Tria

2000
The effects of chronic carvedilol therapy on QT dispersion in patients with congestive heart failure.
    European journal of heart failure, 2001, Volume: 3, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathies; Carvedilol; Dose-Response Re

2001
Becker muscular dystrophy-related cardiomyopathy: a favorable response to medical therapy.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2002, Volume: 21, Issue:4

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Carbazoles; Cardiomyopat

2002