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carvedilol and Cardiac Arrest, Sudden

carvedilol has been researched along with Cardiac Arrest, Sudden in 27 studies

Research Excerpts

ExcerptRelevanceReference
"We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study."9.12Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007)
"Uncertainty persists about the safety and efficacy of amiodarone for the management of heart failure."9.12The safety of amiodarone in patients with heart failure. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, W; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007)
"In a randomized double-blind design, 3029 patients with chronic congestive heart failure requiring diuretic therapy and with left ventricular dysfunction were randomized to treatment with carvedilol (n = 1511) or metoprolol tartrate (n = 1518) and titrated to target doses of 25 mg of carvedilol twice daily or 50 mg of metoprolol tartrate twice daily."9.11Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. ( Cleland, JG; Di Lenarda, A; Hanrath, P; Komajda, M; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Skene, A; Swedberg, K; Torp-Pedersen, C, 2005)
"We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study."5.12Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007)
"Uncertainty persists about the safety and efficacy of amiodarone for the management of heart failure."5.12The safety of amiodarone in patients with heart failure. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, W; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007)
"In a randomized double-blind design, 3029 patients with chronic congestive heart failure requiring diuretic therapy and with left ventricular dysfunction were randomized to treatment with carvedilol (n = 1511) or metoprolol tartrate (n = 1518) and titrated to target doses of 25 mg of carvedilol twice daily or 50 mg of metoprolol tartrate twice daily."5.11Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. ( Cleland, JG; Di Lenarda, A; Hanrath, P; Komajda, M; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Skene, A; Swedberg, K; Torp-Pedersen, C, 2005)
"Carvedilol is an adrenergic antagonist with nonselective beta- and a1-receptor blocking properties that has demonstrated significant clinical benefit in the management of patients with heart failure and in the post-myocardial infarction setting."4.82Carvedilol: beta-blockade and beyond. ( Gheorghiade, M; Stroe, AF, 2004)
"n 1987 the results of the Consensus study were published, and showed that enalapril, an angiotensin convertor enzyme inhibitor (ACEI), was able to modify the clinical course of the heart failure syndrome thereby reducing mortality."4.81[Clinical trials on heart failure]. ( Cosín Aguilar, J; Hernándiz Martínez, A, 2001)
"The effects of carvedilol and metoprolol succinate on appropriate and inappropriate implantable cardioverter defibrillator (ICD) therapy in patients with heart failure with reduced ejection fraction (HFrEF) are not fully understood."3.91A comparison of anti-arrhythmic efficacy of carvedilol vs metoprolol succinate in patients with implantable cardioverter-defibrillators. ( Alqam, B; Ayan, M; Cross, M; Gheith, Z; Habash, F; Paydak, H; Vallurupalli, S, 2019)
"Baroreflex sensitivity was assessed in 287 patients with history of myocardial infarction and left ventricular ejection fraction < or =40% by phenylephrine test and was found to be depressed (4."3.72[Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction]. ( Bozhko, AA; Kanopskiĭ, SG; Staritskiĭ, AG, 2004)
"Hypertension is a major influence on the development of LVH."2.43Ventricular hypertrophy and hypertension: prognostic elements and implications for management. ( Devereux, RB; Krauser, DG, 2006)
"Carvedilol treatment was a strong predictor for being on target dose of BB at time of implant, as was treatment with angiotensin-converting enzyme inhibitors and/or spironolactone, no history of myocardial infarction, younger age and less pronounced heart failure symptoms."1.48The use of guideline recommended beta-blocker therapy in primary prevention implantable cardioverter defibrillator patients: insight from Danish nationwide registers. ( Gislason, GH; Johansen, JB; Jøns, C; Nielsen, JC; Petersen, HH; Riahi, S; Ruwald, AC; Torp-Pedersen, C; Vinther, M, 2018)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's20 (74.07)29.6817
2010's4 (14.81)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Zhang, JG1
Dai, SP1
Liu, H1
Xu, ZS1
Ruwald, AC2
Gislason, GH2
Vinther, M2
Johansen, JB2
Nielsen, JC2
Petersen, HH1
Torp-Pedersen, C5
Riahi, S2
Jøns, C2
Philbert, BT1
Ayan, M1
Habash, F1
Alqam, B1
Gheith, Z1
Cross, M1
Vallurupalli, S1
Paydak, H1
Susa, T1
Kobayashi, S1
Tanaka, T1
Murakami, W1
Akashi, S1
Kunitsugu, I1
Okuda, S1
Doi, M1
Wada, Y1
Nao, T1
Yamada, J1
Ueyama, T1
Okamura, T1
Yano, M1
Matsuzaki, M1
Sinagra, G1
Perkan, A1
Cherubini, A1
Salvatore, L1
Di Lenarda, A4
Isnard, R1
Coca, SG1
Buller, GK1
Stroe, AF1
Gheorghiade, M1
Kanopskiĭ, SG1
Staritskiĭ, AG1
Bozhko, AA1
Poole-Wilson, PA3
Swedberg, K3
Cleland, JG3
Hanrath, P1
Komajda, M3
Lutiger, B1
Metra, M3
Remme, WJ2
Scherhag, A3
Skene, A1
Reiffel, JA1
Kowey, PR1
Paperini, L1
Genovesi, A1
Carluccio, M1
Krauser, DG1
Devereux, RB1
Nakashidze, NM1
Machavariani, PT1
Spark, P2
Moullet, C2
Lukas, MA2
Remme, W1
Nessler, J1
Nessler, B1
Kitliński, M1
Libionka, A1
Kubinyi, A1
Konduracka, E1
Piwowarska, W1
Kanoupakis, EM1
Manios, EG1
Mavrakis, HE1
Kallergis, EM1
Lyrarakis, GM1
Koutalas, EP1
Vardas, PE1
Berruezo, A1
Brugada, J1
Zehender, M1
Just, H1
Fesmire, SI1
Marcoux, LG1
Lyyski, DS1
Sprague, MK1
Kennedy, HL1
Eichhorn, EJ1
Packer, M1
Correia, JM1
Cosín Aguilar, J1
Hernándiz Martínez, A1
Nägele, H1
Schomburg, R1
Petersen, B1
Rödiger, W1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular Events: A Pilot Study[NCT01945268]Phase 4107 participants (Actual)Interventional2015-04-30Completed
A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular Events[NCT02762851]Phase 45,000 participants (Anticipated)Interventional2016-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for carvedilol and Cardiac Arrest, Sudden

ArticleYear
[Treatment of heart failure: an update].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2002, Volume: 3, Issue:7

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidiuretic Hormone Receptor

2002
[Congestive heart failure and acute myocardial infarction: latest trials with beta-blocking agents].
    Annales de cardiologie et d'angeiologie, 2002, Volume: 51, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol;

2002
Carvedilol: beta-blockade and beyond.
    Reviews in cardiovascular medicine, 2004, Volume: 5 Suppl 1

    Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Clinical Trials as Topic;

2004
Drug and drug-device therapy in heart failure patients in the post-COMET and SCD-HeFT era.
    Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme 2; Anti-Arrhythmia Agents; Carbazoles; Ca

2005
A review of carvedilol arrhythmia data in clinical trials.
    Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10 Suppl 1

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Ca

2005
Ventricular hypertrophy and hypertension: prognostic elements and implications for management.
    Herz, 2006, Volume: 31, Issue:4

    Topics: Adrenergic Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convert

2006
[Value of beta-blocker therapy in treatment of coronary heart disease and sudden cardiac death with special reference to carvedilol].
    Zeitschrift fur Kardiologie, 1996, Volume: 85 Suppl 7

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cause of Death; Coronary Disease; Death, Sudden

1996
Current role of beta-adrenergic blockers in the management of chronic heart failure.
    The American journal of medicine, 2001, May-07, Volume: 110 Suppl 7A

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Chron

2001
[Clinical trials on heart failure].
    Revista espanola de cardiologia, 2001, Volume: 54 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme

2001

Trials

8 trials available for carvedilol and Cardiac Arrest, Sudden

ArticleYear
Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET.
    American heart journal, 2005, Volume: 149, Issue:2

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Double-Blind Method; Fe

2005
Drug and drug-device therapy in heart failure patients in the post-COMET and SCD-HeFT era.
    Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme 2; Anti-Arrhythmia Agents; Carbazoles; Ca

2005
[Estimation of effectiveness of the prevention of sudden cardiac death in patients with myocardial infarction].
    Georgian medical news, 2006, Issue:135

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Female; Humans; Male; M

2006
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
The safety of amiodarone in patients with heart failure.
    Journal of cardiac failure, 2007, Volume: 13, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents;

2007
Sudden cardiac death risk factors in patients with heart failure treated with carvedilol.
    Kardiologia polska, 2007, Volume: 65, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Female; He

2007
Electrophysiological effects of carvedilol administration in patients with dilated cardiomyopathy.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:3

    Topics: Action Potentials; Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbazoles; Cardiomyopathy, Di

2008
Dual chamber pacing in patients with severe heart failure on beta blocker and amiodarone treatment: preliminary results of a randomised study.
    Heart (British Cardiac Society), 2002, Volume: 87, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Carbazoles; Cardiac Pacing, Artific

2002

Other Studies

11 other studies available for carvedilol and Cardiac Arrest, Sudden

ArticleYear
Comparison of carvedilol versus metoprolol in patients with acute myocardial infarction: A protocol for systematic review and meta-analysis.
    Medicine, 2021, May-21, Volume: 100, Issue:20

    Topics: Arrhythmias, Cardiac; Carvedilol; Death, Sudden, Cardiac; Humans; Meta-Analysis as Topic; Metoprolol

2021
The use of guideline recommended beta-blocker therapy in primary prevention implantable cardioverter defibrillator patients: insight from Danish nationwide registers.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2018, 02-01, Volume: 20, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Defibrillators, I

2018
Importance of beta-blocker dose in prevention of ventricular tachyarrhythmias, heart failure hospitalizations, and death in primary prevention implantable cardioverter-defibrillator recipients: a Danish nationwide cohort study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2018, 09-01, Volume: 20, Issue:FI2

    Topics: Adrenergic beta-Antagonists; Aged; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable;

2018
A comparison of anti-arrhythmic efficacy of carvedilol vs metoprolol succinate in patients with implantable cardioverter-defibrillators.
    Clinical cardiology, 2019, Volume: 42, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arkansas; Carvedilol; Cause of Death; Death, Su

2019
Urinary 8-hydroxy-2'-deoxyguanosine as a novel biomarker for predicting cardiac events and evaluating the effectiveness of carvedilol treatment in patients with chronic systolic heart failure.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adrenergic beta-Antagonists; Adult; Aged; Biomarkers; Carbazoles; Carve

2012
COMET: a proposed mechanism of action to explain the results and concerns about dose.
    Lancet (London, England), 2003, Sep-27, Volume: 362, Issue:9389

    Topics: Adenosine Triphosphatases; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Carbazoles; Carvedilol

2003
[Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction].
    Kardiologiia, 2004, Volume: 44, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti

2004
[Sudden cardiac death: prevention when is right! From evidence-based medicine to family-based medicine].
    Giornale italiano di cardiologia (2006), 2006, Volume: 7, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Carbazoles; Carvedilol; Death, Su

2006
Betablockers: is the reduction of sudden death related to pure electrophysiologic effects?
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:3

    Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Death, Sudden, Cardiac

2008
Effect of selective versus nonselective beta blockade on QT dispersion in patients with nonischemic dilated cardiomyopathy.
    The American journal of cardiology, 1999, Aug-01, Volume: 84, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Death, Su

1999
[Options in drug combinations].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2001, Volume: 20 Suppl 3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Car

2001