Page last updated: 2024-10-24

carprofen and Osteoarthritis

carprofen has been researched along with Osteoarthritis in 41 studies

carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.

Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.

Research Excerpts

ExcerptRelevanceReference
"A multi-site, masked, randomised parallel group study employing a double dummy treatment design was performed in canine veterinary patients to determine the comparative efficacy and safety of mavacoxib and carprofen in the treatment of pain and inflammation associated with osteoarthritis for a period of 134 days."9.20Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis. ( Becskei, C; Chaudhry, Y; Payne-Johnson, M; Stegemann, MR, 2015)
"To determine the optimal method for use of the Canine Brief Pain Inventory (CBPI) to quantitate responses of dogs with osteoarthritis to treatment with carprofen or placebo."9.17Power of treatment success definitions when the Canine Brief Pain Inventory is used to evaluate carprofen treatment for the control of pain and inflammation in dogs with osteoarthritis. ( Bell, M; Brown, DC; Rhodes, L, 2013)
" In this study, the efficacy and tolerability of robenacoxib were compared with those of carprofen in canine osteoarthritis in a multi-centre, prospective, randomized, blinded, positive-controlled noninferiority clinical trial."9.16Robenacoxib vs. carprofen for the treatment of canine osteoarthritis; a randomized, noninferiority clinical trial. ( Gruet, P; King, JN; Reymond, N; Seewald, W; Speranza, C, 2012)
"The efficacy and tolerability of robenacoxib for the treatment of osteoarthritis in dogs were evaluated in a prospective, multicenter, randomized, noninferiority design clinical trial."9.16Comparison of oral robenacoxib and carprofen for the treatment of osteoarthritis in dogs: a randomized clinical trial. ( Edamura, K; King, JN; Okumura, M; Sakakibara, N; Seewald, W, 2012)
"Results suggested that in dogs with chronic osteoarthritis receiving carprofen because of signs of pain, feeding a diet supplemented with fish oil omega-3 fatty acids may allow for a reduction in carprofen dosage."9.14A multicenter study of the effect of dietary supplementation with fish oil omega-3 fatty acids on carprofen dosage in dogs with osteoarthritis. ( Allen, TA; Brejda, J; Dodd, CE; Fritsch, DA; Hahn, KA; Jewell, DE; Leventhal, PS; Sixby, KA, 2010)
"A double-blind, randomised, controlled, multicentre field study was conducted to compare the safety and efficacy of firocoxib chewable tablets and carprofen tablets in 218 dogs with osteoarthritis."9.12Clinical evaluation of firocoxib and carprofen for the treatment of dogs with osteoarthritis. ( Fleishman, C; Hanson, PD; Pollmeier, M; Toulemonde, C, 2006)
"Thirty-five dogs were included in a randomised, double-blind, positive controlled, multi-centre trial to assess the efficacy of an orally-administered glucosamine hydrochloride and chondroitin sulfate (Glu/CS) combination for the treatment of confirmed osteoarthritis of hips or elbows."9.12Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis. ( Jones, B; McAllister, H; McCarthy, G; Mooney, C; O'Donovan, J; Seed, M, 2007)
"Six medium to large breed dogs with osteoarthritis were treated with 2 mg/kg of racemic carprofen, mixed with their morning feed, daily for 28 days."9.10Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis. ( AliAbadi, FS; Lees, P; Lipscomb, VJ; Muir, P; Pead, MJ, 2002)
"The efficacy, tolerance and ease of administration of a nutraceutical, carprofen or meloxicam were evaluated in a prospective, double-blind study on 71 dogs with osteoarthritis."9.10Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis. ( Bonneau, NH; Desnoyers, M; Dupuis, J; Moreau, M, 2003)
"The pain-relieving effect of carprofen and tolerance to the drug were investigated in 805 dogs that were lame as a result of osteoarthritis."7.74Long-term treatment with carprofen of 805 dogs with osteoarthritis. ( Grøndahl, C; Lønaas, L; Mansa, S; Nyman, G; Palmér, E, 2007)
"To evaluate in vivo activity of carprofen, deracoxib, and etodolac on prostanoid production in several target tissues in dogs with chronic osteoarthritis."7.73In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis. ( Budsberg, SC; Reynolds, LR; Sessions, JK, 2005)
"The purpose of this study was to evaluate the effect of the administration of meloxicam; carprofen; and a slow-acting disease modifying osteoarthritis agent, that contains chondroitin sulfate, purified glucosamine, and manganese ascorbate (CS-G-M), on thyroid function in dogs."7.72Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis. ( Beauchamp, G; Dupuis, J; Moreau, M; Paradis, M; Refsal, KR; Sauvé, F, 2003)
"To determine effects of carprofen and dexamethasone on chondrocytes in a culture model of osteoarthritis (OA)."7.71Effects of carprofen and dexamethasone on canine chondrocytes in a three-dimensional culture model of osteoarthritis. ( Cook, JL; Dvorak, LD; Kreeger, JM; Kuroki, K; Tomlinson, JL, 2002)
"Carprofen is a propionic acid-derived NSAID that has anti-inflammatory, analgesic, and antipyretic activity."6.40Use of carprofen for the treatment of pain and inflammation in dogs. ( Fox, SM; Johnston, SA, 1997)
" In explant culture, low MW HA combined with 12."5.42Effects of low molecular weight hyaluronan combined with carprofen on canine osteoarthritis articular chondrocytes and cartilage explants in vitro. ( Buddhachat, K; Chomdej, S; Euppayo, T; Harada, Y; Nganvongpanit, K; Ongchai, S; Pradit, W; Siengdee, P; Viriyakhasem, N, 2015)
"Carprofen treatment decreased the width of osteophytes (p < 0."5.31Carprofen simultaneously reduces progression of morphological changes in cartilage and subchondral bone in experimental dog osteoarthritis. ( Fernandes, JC; Hilal, G; Jolicoeur, FC; Jovanovic, DV; Lajeunesse, D; Lascau-Coman, V; Martel-Pelletier, J; Pelletier, JP, 2000)
"A multi-site, masked, randomised parallel group study employing a double dummy treatment design was performed in canine veterinary patients to determine the comparative efficacy and safety of mavacoxib and carprofen in the treatment of pain and inflammation associated with osteoarthritis for a period of 134 days."5.20Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis. ( Becskei, C; Chaudhry, Y; Payne-Johnson, M; Stegemann, MR, 2015)
"To determine the optimal method for use of the Canine Brief Pain Inventory (CBPI) to quantitate responses of dogs with osteoarthritis to treatment with carprofen or placebo."5.17Power of treatment success definitions when the Canine Brief Pain Inventory is used to evaluate carprofen treatment for the control of pain and inflammation in dogs with osteoarthritis. ( Bell, M; Brown, DC; Rhodes, L, 2013)
"The efficacy and tolerability of robenacoxib for the treatment of osteoarthritis in dogs were evaluated in a prospective, multicenter, randomized, noninferiority design clinical trial."5.16Comparison of oral robenacoxib and carprofen for the treatment of osteoarthritis in dogs: a randomized clinical trial. ( Edamura, K; King, JN; Okumura, M; Sakakibara, N; Seewald, W, 2012)
" In this study, the efficacy and tolerability of robenacoxib were compared with those of carprofen in canine osteoarthritis in a multi-centre, prospective, randomized, blinded, positive-controlled noninferiority clinical trial."5.16Robenacoxib vs. carprofen for the treatment of canine osteoarthritis; a randomized, noninferiority clinical trial. ( Gruet, P; King, JN; Reymond, N; Seewald, W; Speranza, C, 2012)
" In the carprofen and placebo groups, there was poor correlation between the 2 pain evaluation methods (VAS and HCPI items) at the baseline evaluation, but the correlation improved in the carprofen group over time."5.15Reliability and validity of a visual analogue scale used by owners to measure chronic pain attributable to osteoarthritis in their dogs. ( Hielm-Björkman, AK; Kapatkin, AS; Rita, HJ, 2011)
"Results suggested that in dogs with chronic osteoarthritis receiving carprofen because of signs of pain, feeding a diet supplemented with fish oil omega-3 fatty acids may allow for a reduction in carprofen dosage."5.14A multicenter study of the effect of dietary supplementation with fish oil omega-3 fatty acids on carprofen dosage in dogs with osteoarthritis. ( Allen, TA; Brejda, J; Dodd, CE; Fritsch, DA; Hahn, KA; Jewell, DE; Leventhal, PS; Sixby, KA, 2010)
"To determine whether an activity monitor (AM) could be used to detect changes in activity in dogs with osteoarthritis treated with carprofen or a placebo."5.14Use of an activity monitor to detect response to treatment in dogs with osteoarthritis. ( Boston, RC; Brown, DC; Farrar, JT, 2010)
"Thirty-five dogs were included in a randomised, double-blind, positive controlled, multi-centre trial to assess the efficacy of an orally-administered glucosamine hydrochloride and chondroitin sulfate (Glu/CS) combination for the treatment of confirmed osteoarthritis of hips or elbows."5.12Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis. ( Jones, B; McAllister, H; McCarthy, G; Mooney, C; O'Donovan, J; Seed, M, 2007)
"A double-blind, randomised, controlled, multicentre field study was conducted to compare the safety and efficacy of firocoxib chewable tablets and carprofen tablets in 218 dogs with osteoarthritis."5.12Clinical evaluation of firocoxib and carprofen for the treatment of dogs with osteoarthritis. ( Fleishman, C; Hanson, PD; Pollmeier, M; Toulemonde, C, 2006)
"The efficacy, tolerance and ease of administration of a nutraceutical, carprofen or meloxicam were evaluated in a prospective, double-blind study on 71 dogs with osteoarthritis."5.10Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis. ( Bonneau, NH; Desnoyers, M; Dupuis, J; Moreau, M, 2003)
"Six medium to large breed dogs with osteoarthritis were treated with 2 mg/kg of racemic carprofen, mixed with their morning feed, daily for 28 days."5.10Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis. ( AliAbadi, FS; Lees, P; Lipscomb, VJ; Muir, P; Pead, MJ, 2002)
"The pain-relieving effect of carprofen and tolerance to the drug were investigated in 805 dogs that were lame as a result of osteoarthritis."3.74Long-term treatment with carprofen of 805 dogs with osteoarthritis. ( Grøndahl, C; Lønaas, L; Mansa, S; Nyman, G; Palmér, E, 2007)
"To evaluate in vivo activity of carprofen, deracoxib, and etodolac on prostanoid production in several target tissues in dogs with chronic osteoarthritis."3.73In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis. ( Budsberg, SC; Reynolds, LR; Sessions, JK, 2005)
"The purpose of this study was to evaluate the effect of the administration of meloxicam; carprofen; and a slow-acting disease modifying osteoarthritis agent, that contains chondroitin sulfate, purified glucosamine, and manganese ascorbate (CS-G-M), on thyroid function in dogs."3.72Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis. ( Beauchamp, G; Dupuis, J; Moreau, M; Paradis, M; Refsal, KR; Sauvé, F, 2003)
"To determine effects of carprofen and dexamethasone on chondrocytes in a culture model of osteoarthritis (OA)."3.71Effects of carprofen and dexamethasone on canine chondrocytes in a three-dimensional culture model of osteoarthritis. ( Cook, JL; Dvorak, LD; Kreeger, JM; Kuroki, K; Tomlinson, JL, 2002)
"Treatment with carprofen decreased clot strength and platelet aggregation."2.73Changes in platelet function, hemostasis, and prostaglandin expression after treatment with nonsteroidal anti-inflammatory drugs with various cyclooxygenase selectivities in dogs. ( Brainard, BM; Budsberg, SC; Callan, MB; Driessen, B; Meredith, CP; Otto, CM; Shofer, FS, 2007)
"To evaluate the adverse effects of carprofen in dogs after oral administration for 2 months."2.72Evaluation of adverse effects of long-term orally administered carprofen in dogs. ( Hielm-Björkman, AK; Kejonen, J; Raekallio, MR; Salonen, HM; Sankari, SM, 2006)
"Carprofen is a propionic acid-derived NSAID that has anti-inflammatory, analgesic, and antipyretic activity."2.40Use of carprofen for the treatment of pain and inflammation in dogs. ( Fox, SM; Johnston, SA, 1997)
" In explant culture, low MW HA combined with 12."1.42Effects of low molecular weight hyaluronan combined with carprofen on canine osteoarthritis articular chondrocytes and cartilage explants in vitro. ( Buddhachat, K; Chomdej, S; Euppayo, T; Harada, Y; Nganvongpanit, K; Ongchai, S; Pradit, W; Siengdee, P; Viriyakhasem, N, 2015)
"Suspected adverse reactions (SARs) reported for Cartrophen Vet (100 mg sodium pentosan polysulphate/ml) to the Veterinary Medicines Directorate in the UK for the period January 1991 to October 1999 were reviewed."1.32Safety of Cartrophen Vet in the dog: review of adverse reaction reports in the UK. ( Cawdery, MJ; Cullis-Hill, D; Ghosh, P; Hannon, RL; Smith, JG, 2003)
"Carprofen treatment decreased the width of osteophytes (p < 0."1.31Carprofen simultaneously reduces progression of morphological changes in cartilage and subchondral bone in experimental dog osteoarthritis. ( Fernandes, JC; Hilal, G; Jolicoeur, FC; Jovanovic, DV; Lajeunesse, D; Lascau-Coman, V; Martel-Pelletier, J; Pelletier, JP, 2000)
"Carprofen has a direct influence on chondrocyte activity, resulting in changes in rate of production of cartilage matrix."1.30Effect of carprofen on sulfated glycosaminoglycan metabolism, protein synthesis, and prostaglandin release by cultured osteoarthritic canine chondrocytes. ( Benton, HP; Broderick-Villa, GA; Koolpe, M; Vasseur, PB, 1997)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19906 (14.63)18.7374
1990's5 (12.20)18.2507
2000's15 (36.59)29.6817
2010's14 (34.15)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
White, C1
Morrow, L1
Belshaw, Z1
Brennan, M1
AlRaddadi, EA1
Winter, T1
Aukema, HM1
Miller, DW1
Brown, DC4
Bell, M1
Rhodes, L1
Poulet, B1
de Souza, R1
Knights, CB1
Gentry, C1
Wilson, AM1
Bevan, S1
Chang, YM1
Pitsillides, AA1
Payne-Johnson, M1
Becskei, C1
Chaudhry, Y1
Stegemann, MR1
Bruno, EA1
Guthrie, JW1
Ellwood, SA1
Mellanby, RJ1
Clements, DN1
Euppayo, T1
Siengdee, P1
Buddhachat, K1
Pradit, W1
Viriyakhasem, N1
Chomdej, S1
Ongchai, S1
Harada, Y1
Nganvongpanit, K1
Fernando, N1
Wu, E1
Kou, C1
Martelli, P1
Khong, LF1
Larson, K1
Boston, RC2
Coyne, JC1
Farrar, JT2
Fritsch, DA1
Allen, TA1
Dodd, CE1
Jewell, DE1
Sixby, KA1
Leventhal, PS1
Brejda, J1
Hahn, KA1
Reymond, N1
Speranza, C1
Gruet, P1
Seewald, W2
King, JN2
Hielm-Björkman, AK2
Kapatkin, AS1
Rita, HJ1
Edamura, K1
Sakakibara, N1
Okumura, M1
Dvorak, LD1
Cook, JL1
Kreeger, JM1
Kuroki, K1
Tomlinson, JL1
Moreau, M2
Dupuis, J2
Bonneau, NH1
Desnoyers, M1
Hannon, RL1
Smith, JG1
Cullis-Hill, D1
Ghosh, P1
Cawdery, MJ1
Sauvé, F1
Paradis, M1
Refsal, KR1
Beauchamp, G1
Sessions, JK1
Reynolds, LR1
Budsberg, SC4
Raekallio, MR1
Kejonen, J1
Salonen, HM1
Sankari, SM1
McCarthy, G1
O'Donovan, J1
Jones, B1
McAllister, H1
Seed, M1
Mooney, C1
Pollmeier, M1
Toulemonde, C1
Fleishman, C1
Hanson, PD1
Brainard, BM1
Meredith, CP1
Callan, MB1
Shofer, FS1
Driessen, B1
Otto, CM1
Mansa, S1
Palmér, E1
Grøndahl, C1
Lønaas, L1
Nyman, G1
Liesegang, A1
Limacher, S1
Sobek, A1
Pipino, F1
Busetto, M1
Franchin, F1
Punzi, L1
Todesco, S1
Cozzolino, F1
Costa, L1
Marasco, E1
Kaufmann, S1
Schlumpf, U1
Klein, B1
Knüsel, O1
Vasseur, PB2
Johnson, AL1
Lincoln, JD1
Toombs, JP1
Whitehair, JG1
Lentz, EL1
Benton, HP1
Broderick-Villa, GA1
Koolpe, M1
Fox, SM1
Johnston, SA1
Armstrong, S1
Lees, P2
Pelletier, JP2
Lajeunesse, D2
Hilal, G2
Jovanovic, D1
Fernandes, JC2
Martel-Pelletier, J2
Jovanovic, DV1
Lascau-Coman, V1
Jolicoeur, FC1
Lipscomb, VJ1
AliAbadi, FS1
Pead, MJ1
Muir, P1

Reviews

3 reviews available for carprofen and Osteoarthritis

ArticleYear
Efficacy of meloxicam compared with carprofen for treating canine osteoarthritis.
    The Veterinary record, 2020, Jan-25, Volume: 186, Issue:3

    Topics: Animals; Carbazoles; Dog Diseases; Dogs; Meloxicam; Osteoarthritis; Randomized Controlled Trials as

2020
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
    Schweizerische medizinische Wochenschrift, 1982, Aug-28, Volume: 112, Issue:35

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe

1982
Use of carprofen for the treatment of pain and inflammation in dogs.
    Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1997

Trials

20 trials available for carprofen and Osteoarthritis

ArticleYear
Power of treatment success definitions when the Canine Brief Pain Inventory is used to evaluate carprofen treatment for the control of pain and inflammation in dogs with osteoarthritis.
    American journal of veterinary research, 2013, Volume: 74, Issue:12

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Do

2013
The Canine Orthopedic Index. Step 3: Responsiveness testing.
    Veterinary surgery : VS, 2014, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cohort Studies; Data Collection; Dog D

2014
Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis.
    The Veterinary record, 2015, Mar-14, Volume: 176, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Double-Blind Metho

2015
Ability of the canine brief pain inventory to detect response to treatment in dogs with osteoarthritis.
    Journal of the American Veterinary Medical Association, 2008, Oct-15, Volume: 233, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Double-Blind Metho

2008
A multicenter study of the effect of dietary supplementation with fish oil omega-3 fatty acids on carprofen dosage in dogs with osteoarthritis.
    Journal of the American Veterinary Medical Association, 2010, Mar-01, Volume: 236, Issue:5

    Topics: Animals; Carbazoles; Dietary Supplements; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug

2010
Use of an activity monitor to detect response to treatment in dogs with osteoarthritis.
    Journal of the American Veterinary Medical Association, 2010, Jul-01, Volume: 237, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Female; Male; Moni

2010
Robenacoxib vs. carprofen for the treatment of canine osteoarthritis; a randomized, noninferiority clinical trial.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Diphenylamine; Dog Diseases; Dogs; Fem

2012
Reliability and validity of a visual analogue scale used by owners to measure chronic pain attributable to osteoarthritis in their dogs.
    American journal of veterinary research, 2011, Volume: 72, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chronic Disease; Dog Diseases; Dogs; F

2011
Comparison of oral robenacoxib and carprofen for the treatment of osteoarthritis in dogs: a randomized clinical trial.
    The Journal of veterinary medical science, 2012, Volume: 74, Issue:9

    Topics: Administration, Oral; Analysis of Variance; Animals; Carbazoles; Diphenylamine; Dog Diseases; Dogs;

2012
Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis.
    The Veterinary record, 2003, Mar-15, Volume: 152, Issue:11

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Carbazoles; C

2003
Evaluation of adverse effects of long-term orally administered carprofen in dogs.
    Journal of the American Veterinary Medical Association, 2006, Mar-15, Volume: 228, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Carbazoles;

2006
Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis.
    Veterinary journal (London, England : 1997), 2007, Volume: 174, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chondroitin Sulf

2007
Clinical evaluation of firocoxib and carprofen for the treatment of dogs with osteoarthritis.
    The Veterinary record, 2006, Oct-21, Volume: 159, Issue:17

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; D

2006
Changes in platelet function, hemostasis, and prostaglandin expression after treatment with nonsteroidal anti-inflammatory drugs with various cyclooxygenase selectivities in dogs.
    American journal of veterinary research, 2007, Volume: 68, Issue:3

    Topics: Animals; Aspirin; Carbazoles; Cross-Over Studies; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Fem

2007
[Treatment of osteoarthrosis with a new nonsteroidal anti-inflammatory agent, carprofen].
    La Clinica terapeutica, 1984, Mar-15, Volume: 108, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clinical

1984
[The clinical efficacy and tolerance of a new anti-inflammatory agent, carprofen, in osteoarthritis. Comparative double-blind study with naproxen].
    La Clinica terapeutica, 1983, Sep-30, Volume: 106, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Carbazoles; Clinical Trials as Topic; Double-Blind Method; Dr

1983
Carprofen in osteoarthrosis.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Carbazoles; Clinical Trials as Topic; Double-Blind Method; Drug Adm

1982
Double-blind comparative clinical trial of carprofen versus diclofenac-Na in patients with coxarthrosis.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clinical Trials as Topic; Diclofen

1982
Randomized, controlled trial of the efficacy of carprofen, a nonsteroidal anti-inflammatory drug, in the treatment of osteoarthritis in dogs.
    Journal of the American Veterinary Medical Association, 1995, Mar-15, Volume: 206, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Female; Male; Oste

1995
Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis.
    The Veterinary record, 2002, Jun-01, Volume: 150, Issue:22

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Breeding;

2002

Other Studies

18 other studies available for carprofen and Osteoarthritis

ArticleYear
Are nutraceuticals better than carprofen at controlling osteoarthritis in dogs?
    The Veterinary record, 2018, 10-27, Volume: 183, Issue:16

    Topics: Animals; Carbazoles; Clinical Decision-Making; Controlled Clinical Trials as Topic; Dietary Suppleme

2018
Effects of various dietary supplements on inflammatory processes in primary canine chondrocytes as a model of osteoarthritis.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2019, Volume: 83, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cell Survival; Cells, Cultured; Chondr

2019
Modifications of gait as predictors of natural osteoarthritis progression in STR/Ort mice.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Carbazoles; Disease Models, Animal; Di

2014
Global positioning system derived performance measures are responsive indicators of physical activity, disease and the success of clinical treatments in domestic dogs.
    PloS one, 2015, Volume: 10, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Female; Geographic

2015
Effects of low molecular weight hyaluronan combined with carprofen on canine osteoarthritis articular chondrocytes and cartilage explants in vitro.
    In vitro cellular & developmental biology. Animal, 2015, Volume: 51, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cartilage, Art

2015
MANAGEMENT OF OSTEOARTHRITIS IN A GIANT PANDA (AILUROPODA MELANOLEUCA) WITH MULTIMODAL THERAPY INCLUDING AMANTADINE SULPHATE.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2016, Volume: 47, Issue:1

    Topics: Amantadine; Analgesics, Non-Narcotic; Animals; Animals, Zoo; Anti-Inflammatory Agents, Non-Steroidal

2016
Effects of carprofen and dexamethasone on canine chondrocytes in a three-dimensional culture model of osteoarthritis.
    American journal of veterinary research, 2002, Volume: 63, Issue:10

    Topics: Animals; Carbazoles; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagenases; Dexamethason

2002
Safety of Cartrophen Vet in the dog: review of adverse reaction reports in the UK.
    The Journal of small animal practice, 2003, Volume: 44, Issue:5

    Topics: Adverse Drug Reaction Reporting Systems; Animals; Anti-Inflammatory Agents, Non-Steroidal; Breeding;

2003
Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2003, Volume: 44, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Carbazoles;

2003
In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis.
    American journal of veterinary research, 2005, Volume: 66, Issue:5

    Topics: Animals; Carbazoles; Cyclooxygenase Inhibitors; Dinoprostone; Dog Diseases; Dogs; Drug Administratio

2005
Long-term treatment with carprofen of 805 dogs with osteoarthritis.
    The Veterinary record, 2007, Mar-31, Volume: 160, Issue:13

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Do

2007
The effect of carprofen on selected markers of bone metabolism in dogs with chronic osteoarthritis.
    Schweizer Archiv fur Tierheilkunde, 2007, Volume: 149, Issue:8

    Topics: Age Factors; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Bon

2007
[Clinical experiences with the antirheumatism agent carprofen].
    Die Medizinische Welt, 1983, Dec-02, Volume: 34, Issue:48

    Topics: Arthritis, Rheumatoid; Carbazoles; Female; Humans; Male; Middle Aged; Osteoarthritis; Spondylitis, A

1983
Effect of carprofen on sulfated glycosaminoglycan metabolism, protein synthesis, and prostaglandin release by cultured osteoarthritic canine chondrocytes.
    American journal of veterinary research, 1997, Volume: 58, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cartilage, Articular; Cell Division; C

1997
Effects of R and S enantiomers and a racemic mixture of carprofen on the production and release of proteoglycan and prostaglandin E2 from equine chondrocytes and cartilage explants.
    American journal of veterinary research, 1999, Volume: 60, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cartilage, Articular; Cells, Cultured;

1999
Carprofen reduces the structural changes and the abnormal subchondral bone metabolism of experimental osteoarthritis.
    Osteoarthritis and cartilage, 1999, Volume: 7, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Bone Remodeling; Carbazoles; Carti

1999
Carprofen simultaneously reduces progression of morphological changes in cartilage and subchondral bone in experimental dog osteoarthritis.
    The Journal of rheumatology, 2000, Volume: 27, Issue:12

    Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Carbazoles;

2000
Long-term temporal evaluation of ground reaction forces during development of experimentally induced osteoarthritis in dogs.
    American journal of veterinary research, 2001, Volume: 62, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Carbazoles; Dog Diseases;

2001