carprofen has been researched along with Innate Inflammatory Response in 20 studies
carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the analgesic efficacy of grapiprant to carprofen for the treatment of postoperative pain and inflammation in dogs following ovariohysterectomy." | 9.51 | Preliminary evaluation of the effects of grapiprant compared with carprofen on acute pain and inflammation following ovariohysterectomy in dogs. ( Barnes, DN; Enomoto, H; Long, SM; Messenger, KM; Southern, BL, 2022) |
| "A multi-site, masked, randomised parallel group study employing a double dummy treatment design was performed in canine veterinary patients to determine the comparative efficacy and safety of mavacoxib and carprofen in the treatment of pain and inflammation associated with osteoarthritis for a period of 134 days." | 9.20 | Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis. ( Becskei, C; Chaudhry, Y; Payne-Johnson, M; Stegemann, MR, 2015) |
| "After saline, hyperalgesia was detected from 2-6 h, 22-26 h, and at 30 and 36 h." | 6.73 | Carprofen and buprenorphine prevent hyperalgesia in a model of inflammatory pain in cats. ( Dixon, MJ; Ferreira, TH; Luna, SP; Steagall, PV; Taylor, PM, 2007) |
| "To compare the analgesic efficacy of grapiprant to carprofen for the treatment of postoperative pain and inflammation in dogs following ovariohysterectomy." | 5.51 | Preliminary evaluation of the effects of grapiprant compared with carprofen on acute pain and inflammation following ovariohysterectomy in dogs. ( Barnes, DN; Enomoto, H; Long, SM; Messenger, KM; Southern, BL, 2022) |
| "A multi-site, masked, randomised parallel group study employing a double dummy treatment design was performed in canine veterinary patients to determine the comparative efficacy and safety of mavacoxib and carprofen in the treatment of pain and inflammation associated with osteoarthritis for a period of 134 days." | 5.20 | Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis. ( Becskei, C; Chaudhry, Y; Payne-Johnson, M; Stegemann, MR, 2015) |
| " We generated a mouse-specific dose-response curve by using the CPE assay for robenacoxib doses of 3." | 2.87 | Analgesic Efficacy and Hematologic Effects of Robenacoxib in Mice. ( Beninson, JA; Berkowitz, DJ; Hileman, MM; Lester, PA; Lofgren, JL; Myers, DD, 2018) |
| "After saline, hyperalgesia was detected from 2-6 h, 22-26 h, and at 30 and 36 h." | 2.73 | Carprofen and buprenorphine prevent hyperalgesia in a model of inflammatory pain in cats. ( Dixon, MJ; Ferreira, TH; Luna, SP; Steagall, PV; Taylor, PM, 2007) |
| " The objective of this study was to determine the unbound concentration of carprofen in canine interstitial fluid (ISF) using in vivo ultrafiltration and to compare pharmacokinetic parameters of free carprofen concentrations between inflamed and control tissue sites." | 1.43 | Carprofen pharmacokinetics in plasma and in control and inflamed canine tissue fluid using in vivo ultrafiltration. ( Messenger, KM; Papich, MG; Wofford, JA, 2016) |
| "Because inflammation is critical to both the development and resolution of VT, analgesic medications have the potential to adversely affect multiple parameters of interest in VT research." | 1.40 | Effects of analgesic use on inflammation and hematology in a murine model of venous thrombosis. ( Diaz, JA; Hawley, AE; Hish, GA; Lester, PA; Myers, DD, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 14 (70.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Southern, BL | 1 |
| Long, SM | 1 |
| Barnes, DN | 1 |
| Enomoto, H | 2 |
| Messenger, KM | 2 |
| Jones, SM | 1 |
| Gaier, A | 1 |
| Ishii, P | 1 |
| Pilla, R | 1 |
| Price, J | 1 |
| Suchodolski, J | 1 |
| Steiner, JM | 1 |
| Papich, MG | 2 |
| Messenger, K | 1 |
| Tolbert, MK | 1 |
| Smeester, BA | 1 |
| Lee, JH | 1 |
| Beitz, AJ | 1 |
| Shepherd, AJ | 1 |
| Mohapatra, DP | 1 |
| Beninson, JA | 1 |
| Lofgren, JL | 1 |
| Lester, PA | 2 |
| Hileman, MM | 1 |
| Berkowitz, DJ | 1 |
| Myers, DD | 2 |
| Krishnan, V | 1 |
| Booker, D | 1 |
| Cunningham, G | 1 |
| Jadapalli, JK | 1 |
| Kain, V | 1 |
| Pullen, AB | 1 |
| Halade, GV | 1 |
| AlRaddadi, EA | 1 |
| Winter, T | 1 |
| Aukema, HM | 1 |
| Miller, DW | 1 |
| Hish, GA | 1 |
| Diaz, JA | 1 |
| Hawley, AE | 1 |
| Payne-Johnson, M | 1 |
| Becskei, C | 1 |
| Chaudhry, Y | 1 |
| Stegemann, MR | 1 |
| Vailati Riboni, M | 1 |
| Meier, S | 1 |
| Priest, NV | 1 |
| Burke, CR | 1 |
| Kay, JK | 1 |
| McDougall, S | 1 |
| Mitchell, MD | 1 |
| Walker, CG | 1 |
| Crookenden, M | 1 |
| Heiser, A | 1 |
| Roche, JR | 1 |
| Loor, JJ | 1 |
| Wofford, JA | 1 |
| Pang, WY | 1 |
| Earley, B | 1 |
| Murray, M | 1 |
| Sweeney, T | 1 |
| Gath, V | 1 |
| Crowe, MA | 1 |
| Essien, BE | 1 |
| Kotiw, M | 1 |
| Clutterbuck, AL | 1 |
| Smith, JR | 1 |
| Allaway, D | 1 |
| Harris, P | 1 |
| Liddell, S | 1 |
| Mobasheri, A | 1 |
| Pinard, CL | 1 |
| Gauvin, D | 1 |
| Moreau, M | 1 |
| Martel-Pelletier, J | 1 |
| Pelletier, JP | 1 |
| Troncy, E | 1 |
| Bryant, CE | 1 |
| Farnfield, BA | 1 |
| Janicke, HJ | 1 |
| Taylor, PM | 1 |
| Steagall, PV | 1 |
| Dixon, MJ | 1 |
| Ferreira, TH | 1 |
| Luna, SP | 1 |
| Lees, P | 1 |
| Delatour, P | 1 |
| Foster, AP | 1 |
| Foot, R | 1 |
| Baggot, D | 1 |
7 trials available for carprofen and Innate Inflammatory Response
| Article | Year |
|---|---|
Preliminary evaluation of the effects of grapiprant compared with carprofen on acute pain and inflammation following ovariohysterectomy in dogs.
Topics: Acute Pain; Animals; Carbazoles; Dinoprostone; Dog Diseases; Dogs; Female; Hysterectomy; Imidazoles; | 2022 |
The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Female; Inflammati | 2020 |
Analgesic Efficacy and Hematologic Effects of Robenacoxib in Mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Diphenylamine; Dose-Respon | 2018 |
Comparative efficacy and safety of mavacoxib and carprofen in the treatment of canine osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Double-Blind Metho | 2015 |
Banding or Burdizzo castration and carprofen administration on peripheral leukocyte inflammatory cytokine transcripts.
Topics: Animals; Carbazoles; Cattle; Cytokines; Gene Expression Regulation; Hydrocortisone; Inflammation; Le | 2011 |
Measurements of canine aqueous humor inflammatory mediators and the effect of carprofen following anterior chamber paracentesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Carbazoles; Cyclooxygenase 2; Dinop | 2011 |
Carprofen and buprenorphine prevent hyperalgesia in a model of inflammatory pain in cats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Carbazoles; Cat Diseases; Cats; Cro | 2007 |
13 other studies available for carprofen and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Influence of social interaction on nociceptive-induced changes in locomotor activity in a mouse model of acute inflammatory pain: Use of novel thermal assays.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Disease Models, Animal; Freund's Adjuv | 2017 |
Pharmacological validation of voluntary gait and mechanical sensitivity assays associated with inflammatory and neuropathic pain in mice.
Topics: Analgesics; Animals; Buprenorphine; Carbazoles; Disease Models, Animal; Female; Freund's Adjuvant; G | 2018 |
Pretreatment of carprofen impaired initiation of inflammatory- and overlapping resolution response and promoted cardiorenal syndrome in heart failure.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Carbazoles; Cardio-Renal Syndrome; Cyt | 2019 |
Effects of various dietary supplements on inflammatory processes in primary canine chondrocytes as a model of osteoarthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cell Survival; Cells, Cultured; Chondr | 2019 |
Effects of analgesic use on inflammation and hematology in a murine model of venous thrombosis.
Topics: Analgesics; Anesthetics, Local; Animals; Bupivacaine; Buprenorphine; Carbazoles; Disease Models, Ani | 2014 |
Adipose and liver gene expression profiles in response to treatment with a nonsteroidal antiinflammatory drug after calving in grazing dairy cows.
Topics: Adipose Tissue; Animal Husbandry; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Catt | 2015 |
Carprofen pharmacokinetics in plasma and in control and inflamed canine tissue fluid using in vivo ultrafiltration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Body Fluids; Carbazoles; Carrage | 2016 |
Anti-inflammatory activity of hyperimmune plasma in a lipopolysaccharide-mediated rat air pouch model of inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dogs; Immune Sera; Inflammation; Leuko | 2012 |
High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cartilage, Articular; Gene Expression | 2011 |
Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cell Line; Clonixin; Cyclooxygenase In | 2003 |
Special symposium on mechanisms in rheumatoid inflammation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Humans; Inflammation | 1982 |
Evaluation of carprofen in calves using a tissue cage model of inflammation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acute Disease; Animals; Anti-Inflammatory Agents, Non-St | 1996 |