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carprofen and Hemolysis

carprofen has been researched along with Hemolysis in 3 studies

carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
" Eight NSAID (carprofen, diclofenac, ibuprofen, ketoprofen, naproxen, piroxicam, phenylbutazone, tiaprofenic acid) were assessed in a photohemolysis test for phototoxic effects in the visible light range."3.69Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light. ( Becker, L; Eberlein-König, B; Przybilla, B, 1996)
" However, the biological activity of 2a in the linoleic acid photoperoxidation and photohemolysis tests is markedly lower than that of 1a, which constitutes further evidence in favor of the important role of photodehalogenation in the adverse photobiological effects of carprofen."3.69Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen. ( Bosca, F; Encinas, S; Heelis, PF; Miranda, MA, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Guidi, G1
Chillemi, R1
Costanzo, LL1
Giuffrida, S1
Condorelli, G1
Becker, L1
Eberlein-König, B1
Przybilla, B1
Bosca, F1
Encinas, S1
Heelis, PF1
Miranda, MA1

Other Studies

3 other studies available for carprofen and Hemolysis

ArticleYear
Molecular mechanism of drug photosensitization. 4. Photohemolysis sensitized by carprofen.
    Journal of photochemistry and photobiology. B, Biology, 1993, Volume: 17, Issue:3

    Topics: Aerobiosis; Anaerobiosis; Azides; Butylated Hydroxytoluene; Carbazoles; Erythrocyte Membrane; Erythr

1993
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
    Acta dermato-venereologica, 1996, Volume: 76, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocyte

1996
Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen.
    Chemical research in toxicology, 1997, Volume: 10, Issue:7

    Topics: Carbazoles; Energy Transfer; Erythrocytes; Fluorescence; Hemolysis; Humans; Lasers; Linoleic Acid; L

1997