carprofen has been researched along with Gait Disorders, Animal in 21 studies
carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the ability of a proprietary antagonist of E-type prostanoid receptor (EP) 4, grapiprant, and carprofen to attenuate lameness attributable to urate-induced synovitis in dogs." | 9.30 | Comparison of two inhibitors of E-type prostanoid receptor four and carprofen in dogs with experimentally induced acute synovitis. ( Budsberg, SC; Kleine, SA; Norton, MM; Sandberg, GS, 2019) |
| "A randomized, placebo-controlled, four-period cross-over laboratory study involving eight dogs was conducted to confirm the effective analgesic dose of firocoxib, a selective COX-2 inhibitor, in a synovitis model of arthritis." | 9.13 | Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs. ( Hanson, PD; Hazewinkel, HA; Pollmeier, M; Theyse, LF; van den Brom, WE, 2008) |
| "This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness." | 9.12 | Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs. ( Drag, M; Hanson, PD; Kunkle, BN; Romano, D, 2007) |
| "The efficacy, tolerance and ease of administration of a nutraceutical, carprofen or meloxicam were evaluated in a prospective, double-blind study on 71 dogs with osteoarthritis." | 9.10 | Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis. ( Bonneau, NH; Desnoyers, M; Dupuis, J; Moreau, M, 2003) |
| "Six medium to large breed dogs with osteoarthritis were treated with 2 mg/kg of racemic carprofen, mixed with their morning feed, daily for 28 days." | 9.10 | Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis. ( AliAbadi, FS; Lees, P; Lipscomb, VJ; Muir, P; Pead, MJ, 2002) |
| "The pain-relieving effect of carprofen and tolerance to the drug were investigated in 805 dogs that were lame as a result of osteoarthritis." | 7.74 | Long-term treatment with carprofen of 805 dogs with osteoarthritis. ( Grøndahl, C; Lønaas, L; Mansa, S; Nyman, G; Palmér, E, 2007) |
| "Synovitis was induced in 1 stifle joint during each treatment by intra-articular injection of sodium urate (SU)." | 6.94 | Comparison of the effects on lameness of orally administered acetaminophen-codeine and carprofen in dogs with experimentally induced synovitis. ( Budsberg, SC; Kleine, SA; Norton, MM; Papich, MG; Sandberg, GS, 2020) |
| "To determine the efficacy and bioavailability of non-steroidal anti-inflammatory drugs (NSAIDs) when administered orally to sheep." | 6.80 | Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. ( Colditz, IG; Hinch, G; Lee, C; Marini, D; Petherick, JC; Pippia, J, 2015) |
| "Carprofen was also somewhat effective in attenuating the severity of urate-induced synovitis but to a lesser degree than the medium dose of deracoxib." | 6.70 | Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs. ( Buonomo, FC; Millis, DL; Moyers, T; Weigel, JP, 2002) |
| "To investigate the ability of a proprietary antagonist of E-type prostanoid receptor (EP) 4, grapiprant, and carprofen to attenuate lameness attributable to urate-induced synovitis in dogs." | 5.30 | Comparison of two inhibitors of E-type prostanoid receptor four and carprofen in dogs with experimentally induced acute synovitis. ( Budsberg, SC; Kleine, SA; Norton, MM; Sandberg, GS, 2019) |
| " Our results suggest that analgesic treatment with ABT-116 is not as effective as carprofen or tramadol for treatment of hip arthritis pain in client-owned dogs." | 5.16 | Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis. ( Bleedorn, JA; Cozzi, EM; Holzman, G; Jacobson, PB; Malek, S; Muir, P; Nemke, B; Sample, SJ; Schaefer, SL; Schwartz, Z, 2012) |
| "To determine whether carprofen, a commercially available NSAID, would decrease perceived exertion and signs of pain in dogs and therefore increase muscle mass and hind limb function without decreasing range of motion after lateral fabellar suture stabilization." | 5.15 | Effect of the use of carprofen in dogs undergoing intense rehabilitation after lateral fabellar suture stabilization. ( Dunning, D; Gordon-Evans, WJ; Johnson, AL; Knap, KE, 2011) |
| "A randomized, placebo-controlled, four-period cross-over laboratory study involving eight dogs was conducted to confirm the effective analgesic dose of firocoxib, a selective COX-2 inhibitor, in a synovitis model of arthritis." | 5.13 | Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs. ( Hanson, PD; Hazewinkel, HA; Pollmeier, M; Theyse, LF; van den Brom, WE, 2008) |
| "This positive-control study evaluated the efficacy of firocoxib versus carprofen, deracoxib, and meloxicam for the prevention of pain and inflammation in a urate crystal synovitis model of lameness." | 5.12 | Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs. ( Drag, M; Hanson, PD; Kunkle, BN; Romano, D, 2007) |
| "The optimum doses of carprofen, flunixin, ketoprofen and sodium salicylate for the treatment of inflammatory pain were determined in domestic fowl using the microcrystalline sodium urate model of articular pain." | 5.11 | Effects of non-steroidal anti-inflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl. ( Gentle, MJ; Hocking, PM; Robertson, GW, 2005) |
| "The efficacy, tolerance and ease of administration of a nutraceutical, carprofen or meloxicam were evaluated in a prospective, double-blind study on 71 dogs with osteoarthritis." | 5.10 | Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis. ( Bonneau, NH; Desnoyers, M; Dupuis, J; Moreau, M, 2003) |
| "Six medium to large breed dogs with osteoarthritis were treated with 2 mg/kg of racemic carprofen, mixed with their morning feed, daily for 28 days." | 5.10 | Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis. ( AliAbadi, FS; Lees, P; Lipscomb, VJ; Muir, P; Pead, MJ, 2002) |
| "The pain-relieving effect of carprofen and tolerance to the drug were investigated in 805 dogs that were lame as a result of osteoarthritis." | 3.74 | Long-term treatment with carprofen of 805 dogs with osteoarthritis. ( Grøndahl, C; Lønaas, L; Mansa, S; Nyman, G; Palmér, E, 2007) |
| "Synovitis was induced in 1 stifle joint during each treatment by intra-articular injection of sodium urate (SU)." | 2.94 | Comparison of the effects on lameness of orally administered acetaminophen-codeine and carprofen in dogs with experimentally induced synovitis. ( Budsberg, SC; Kleine, SA; Norton, MM; Papich, MG; Sandberg, GS, 2020) |
| "To determine the efficacy and bioavailability of non-steroidal anti-inflammatory drugs (NSAIDs) when administered orally to sheep." | 2.80 | Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. ( Colditz, IG; Hinch, G; Lee, C; Marini, D; Petherick, JC; Pippia, J, 2015) |
| "On the fourth day after initiation of treatment, synovitis was induced via intra-articular injection of SU 1 hour before administration of the last treatment dose." | 2.76 | Effect of perzinfotel and a proprietary phospholipase A(2) inhibitor on kinetic gait and subjective lameness scores in dogs with sodium urate-induced synovitis. ( Al-Nadaf, S; Budsberg, SC; Cathcart, CJ; Clark, JD; Eppler, CM; Reynolds, LR; Torres, BT; Zwijnenberg, RJ, 2011) |
| "Carprofen was also somewhat effective in attenuating the severity of urate-induced synovitis but to a lesser degree than the medium dose of deracoxib." | 2.70 | Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs. ( Buonomo, FC; Millis, DL; Moyers, T; Weigel, JP, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Budsberg, SC | 4 |
| Kleine, SA | 2 |
| Norton, MM | 2 |
| Sandberg, GS | 2 |
| Papich, MG | 1 |
| Poulet, B | 1 |
| de Souza, R | 1 |
| Knights, CB | 1 |
| Gentry, C | 1 |
| Wilson, AM | 1 |
| Bevan, S | 1 |
| Chang, YM | 1 |
| Pitsillides, AA | 1 |
| Marini, D | 1 |
| Pippia, J | 1 |
| Colditz, IG | 1 |
| Hinch, G | 1 |
| Petherick, JC | 1 |
| Lee, C | 1 |
| Teixeira, LR | 1 |
| Luna, SP | 1 |
| Matsubara, LM | 1 |
| Cápua, ML | 1 |
| Santos, BP | 1 |
| Mesquita, LR | 1 |
| Faria, LG | 1 |
| Agostinho, FS | 1 |
| Hielm-Björkman, A | 1 |
| Torres, BT | 1 |
| Zwijnenberg, RJ | 1 |
| Eppler, CM | 1 |
| Clark, JD | 1 |
| Cathcart, CJ | 1 |
| Reynolds, LR | 1 |
| Al-Nadaf, S | 1 |
| Gordon-Evans, WJ | 1 |
| Dunning, D | 1 |
| Johnson, AL | 1 |
| Knap, KE | 1 |
| Malek, S | 1 |
| Sample, SJ | 1 |
| Schwartz, Z | 1 |
| Nemke, B | 1 |
| Jacobson, PB | 1 |
| Cozzi, EM | 1 |
| Schaefer, SL | 1 |
| Bleedorn, JA | 1 |
| Holzman, G | 1 |
| Muir, P | 2 |
| Caplen, G | 1 |
| Colborne, GR | 1 |
| Hothersall, B | 1 |
| Nicol, CJ | 1 |
| Waterman-Pearson, AE | 3 |
| Weeks, CA | 2 |
| Murrell, JC | 1 |
| Millis, DL | 1 |
| Weigel, JP | 1 |
| Moyers, T | 1 |
| Buonomo, FC | 1 |
| Moreau, M | 1 |
| Dupuis, J | 2 |
| Bonneau, NH | 2 |
| Desnoyers, M | 1 |
| Corr, SA | 1 |
| Maxwell, M | 1 |
| Gentle, MJ | 2 |
| Bennett, D | 1 |
| Grisneaux, E | 1 |
| Pibarot, P | 1 |
| Charette, B | 1 |
| Blais, D | 1 |
| Hocking, PM | 1 |
| Robertson, GW | 1 |
| Mansa, S | 1 |
| Palmér, E | 1 |
| Grøndahl, C | 1 |
| Lønaas, L | 1 |
| Nyman, G | 1 |
| Hazewinkel, HA | 1 |
| van den Brom, WE | 1 |
| Theyse, LF | 1 |
| Pollmeier, M | 1 |
| Hanson, PD | 2 |
| Drag, M | 1 |
| Kunkle, BN | 1 |
| Romano, D | 1 |
| McGeown, D | 1 |
| Danbury, TC | 2 |
| Kestin, SC | 2 |
| Chambers, JP | 1 |
| Lipscomb, VJ | 1 |
| AliAbadi, FS | 1 |
| Lees, P | 1 |
| Pead, MJ | 1 |
16 trials available for carprofen and Gait Disorders, Animal
| Article | Year |
|---|---|
Comparison of two inhibitors of E-type prostanoid receptor four and carprofen in dogs with experimentally induced acute synovitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cross-Over Studies; Dog Diseases; Dogs | 2019 |
Comparison of the effects on lameness of orally administered acetaminophen-codeine and carprofen in dogs with experimentally induced synovitis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Codeine; Cross-Over Stu | 2020 |
Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Car | 2015 |
Owner assessment of chronic pain intensity and results of gait analysis of dogs with hip dysplasia treated with acupuncture.
Topics: Acupuncture Therapy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chronic Pain; Dog | 2016 |
Effect of perzinfotel and a proprietary phospholipase A(2) inhibitor on kinetic gait and subjective lameness scores in dogs with sodium urate-induced synovitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azabicyclo Compounds; Blood Proteins; Carbazoles; | 2011 |
Effect of the use of carprofen in dogs undergoing intense rehabilitation after lateral fabellar suture stabilization.
Topics: Animals; Anterior Cruciate Ligament; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomen | 2011 |
Effect of analgesic therapy on clinical outcome measures in a randomized controlled trial using client-owned dogs with hip osteoarthritis.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Carbazoles; | 2012 |
Lame broiler chickens respond to non-steroidal anti-inflammatory drugs with objective changes in gait function: a controlled clinical trial.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chickens; Gait; Lameness, Animal; Melo | 2013 |
Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cyclooxygenase I | 2002 |
Clinical evaluation of a nutraceutical, carprofen and meloxicam for the treatment of dogs with osteoarthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Carbazoles; C | 2003 |
Preliminary study of joint disease in poultry by the analysis of synovial fluid.
Topics: Animal Husbandry; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carbazoles; Chickens; | 2003 |
Effects of postoperative administration of ketoprofen or carprofen on short- and long-term results of femoral head and neck excision in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Dogs; Double-Blind Metho | 2003 |
Effects of non-steroidal anti-inflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chickens; Clonixin; Dose-Response Rela | 2005 |
Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carbazoles; Cross-Over | 2008 |
Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs.
Topics: 4-Butyrolactone; Animals; Carbazoles; Cyclooxygenase 2 Inhibitors; Dog Diseases; Dogs; Female; Lamen | 2007 |
Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Breeding; | 2002 |
5 other studies available for carprofen and Gait Disorders, Animal
| Article | Year |
|---|---|
Modifications of gait as predictors of natural osteoarthritis progression in STR/Ort mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Carbazoles; Disease Models, Animal; Di | 2014 |
Long-term treatment with carprofen of 805 dogs with osteoarthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dog Diseases; Do | 2007 |
Effect of carprofen on lameness in broiler chickens.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chickens; Lameness, Animal; Pain Measu | 1999 |
Self-selection of the analgesic drug carprofen by lame broiler chickens.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chickens; Condit | 2000 |
Long-term temporal evaluation of ground reaction forces during development of experimentally induced osteoarthritis in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Carbazoles; Dog Diseases; | 2001 |