carprofen has been researched along with Bone Loss, Osteoclastic in 2 studies
carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We looked for a dual effect on bone resorption by comparing the early and late effects of prostaglandin E1 (PGE1), prostacyclin (PGI2), 6 alpha-carbaprostaglandin I2 (C-PGI2), a carbon substituted analog of PGI2, and salmon calcitonin (CT) on the release of previously incorporated 45Ca from fetal rat long bones cultured in the presence of an inhibitor of cyclooxygenase, RO-20-5720." | 1.27 | Effects of prostacyclin and prostaglandin E1 (PGE1) on bone resorption in the presence and absence of parathyroid hormone. ( Conaway, HH; Diez, LF; Raisz, LG, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sandberg, AL | 1 |
| Raisz, LG | 2 |
| Wahl, LM | 1 |
| Simmons, HA | 1 |
| Conaway, HH | 1 |
| Diez, LF | 1 |
2 other studies available for carprofen and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Enhancement of complement-mediated prostaglandin synthesis and bone resorption by arachidonic acid and inhibition by cortisol.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bone and Bones; Bone Resorption; Calcium; Carbazoles; | 1982 |
Effects of prostacyclin and prostaglandin E1 (PGE1) on bone resorption in the presence and absence of parathyroid hormone.
Topics: Alprostadil; Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Carbazoles; Epoprostenol | 1986 |