carprofen has been researched along with Arthritis, Rheumatoid in 15 studies
carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-eight patients with active, definite, or classical rheumatoid arthritis were tested in a double-blind, 3-week-per-arm, multiple-crossover, randomized, block-design comparison of 100, 300, 600, and 800 mg/day carprofen given b." | 9.06 | Serum concentration and dose-response relationships for carprofen in rheumatoid arthritis. ( Caldwell, JR; Dromgoole, S; Enthoven, D; Furst, DE; Klugman, MP; Rittweger, K; Sarkissian, E; Scheer, R, 1988) |
| "Concentrations of carprofen in the serum and the synovial fluid were determined in 13 patients with classical or confirmed rheumatoid arthritis." | 7.66 | Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients. ( Heizmann, P; Jalava, S; Kylmämaa, T, 1983) |
| "Thirty-eight patients with active, definite, or classical rheumatoid arthritis were tested in a double-blind, 3-week-per-arm, multiple-crossover, randomized, block-design comparison of 100, 300, 600, and 800 mg/day carprofen given b." | 5.06 | Serum concentration and dose-response relationships for carprofen in rheumatoid arthritis. ( Caldwell, JR; Dromgoole, S; Enthoven, D; Furst, DE; Klugman, MP; Rittweger, K; Sarkissian, E; Scheer, R, 1988) |
| "Concentrations of carprofen in the serum and the synovial fluid were determined in 13 patients with classical or confirmed rheumatoid arthritis." | 3.66 | Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients. ( Heizmann, P; Jalava, S; Kylmämaa, T, 1983) |
| "Prednisone-treated dogs were more likely to develop polyuria, polydipsia, and polyphagia than were cyclosporine-treated dogs." | 2.82 | Comparison of the efficacy of prednisone and cyclosporine for treatment of dogs with primary immune-mediated polyarthritis. ( Herrera, MA; Kass, PH; Rhoades, AC; Sykes, JE; Vernau, W, 2016) |
| " For most of the efficacy variables studied, the carprofen high dosage regimen at weeks 5 and 6 was shown statistically superior or at least not different from the indomethacin group; both of these were superior to the carprofen low dosage regimen." | 2.65 | Comparative evaluation of carprofen and indomethacin in rheumatoid patients. ( Caron, M; Lussier, A; Rouleau, L; Tétreault, L, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rhoades, AC | 1 |
| Vernau, W | 1 |
| Kass, PH | 1 |
| Herrera, MA | 1 |
| Sykes, JE | 1 |
| Ceuppens, JL | 2 |
| Rodriguez, MA | 1 |
| Goodwin, JS | 3 |
| Jalava, S | 2 |
| Hoting, E | 1 |
| Schulz, KH | 1 |
| Heizmann, P | 1 |
| Kylmämaa, T | 1 |
| Kaufmann, S | 1 |
| Isomäki, H | 2 |
| Martio, J | 1 |
| Kaarela, K | 1 |
| Kajander, A | 1 |
| Koota, K | 1 |
| Lehtinen, K | 1 |
| Luukkainen, R | 1 |
| Martio, T | 1 |
| Nissilä, M | 2 |
| Nuotio, P | 2 |
| Schlumpf, U | 1 |
| Standel, W | 1 |
| Lussier, A | 1 |
| Rouleau, L | 1 |
| Caron, M | 1 |
| Tétreault, L | 1 |
| Furst, DE | 1 |
| Caldwell, JR | 1 |
| Klugman, MP | 1 |
| Enthoven, D | 1 |
| Rittweger, K | 1 |
| Scheer, R | 1 |
| Sarkissian, E | 1 |
| Dromgoole, S | 1 |
| Seppälä, E | 1 |
| Nykänen, E | 1 |
| Laitinen, O | 1 |
| Vapaatalo, H | 1 |
3 reviews available for carprofen and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Effect of nonsteroidal antiinflammatory drugs on immune function.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; Carbazole | 1983 |
Mechanism of action of nonsteroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Carba | 1984 |
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe | 1982 |
6 trials available for carprofen and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Comparison of the efficacy of prednisone and cyclosporine for treatment of dogs with primary immune-mediated polyarthritis.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agent | 2016 |
A double blind crossover study of carprofen and indomethacin in patients with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Carbazoles; Clinical Trials as Topic; Double-Blind Method; Female; Hum | 1983 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazol | 1984 |
Clinical trials in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Clinical Trials as Topic; | 1982 |
Comparative evaluation of carprofen and indomethacin in rheumatoid patients.
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Clinical Trials | 1980 |
Serum concentration and dose-response relationships for carprofen in rheumatoid arthritis.
Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; C | 1988 |
6 other studies available for carprofen and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Non-steroidal anti-inflammatory agent inhibit the synthesis of IgM rheumatoid factor in vitro.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Cells, Cultured; Depressio | 1982 |
[Photoallergic reaction to carprofen].
Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Drug Hypersensitivity; Female; Hu | 1984 |
Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Humans; Synovial Fluid | 1983 |
[Clinical experiences with the antirheumatism agent carprofen].
Topics: Arthritis, Rheumatoid; Carbazoles; Female; Humans; Male; Middle Aged; Osteoarthritis; Spondylitis, A | 1983 |
Special symposium on mechanisms in rheumatoid inflammation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Humans; Inflammation | 1982 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspiri | 1985 |