Page last updated: 2024-10-24

carprofen and Anastomotic Leak

carprofen has been researched along with Anastomotic Leak in 2 studies

carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.

Anastomotic Leak: Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.

Research Excerpts

ExcerptRelevanceReference
"The authors examined the potential of the cyclooxygenase 2 (COX-2) inhibitor carprofen to reproducibly induce anastomotic leakage."3.79Perioperative pain relief by a COX-2 inhibitor affects ileal repair and provides a model for anastomotic leakage in the intestine. ( de Man, BM; Hendriks, T; Lomme, RM; van der Vijver, RJ; van Laarhoven, CJ, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van der Vijver, RJ2
van Laarhoven, CJ2
de Man, BM1
Lomme, RM2
Hendriks, T2

Other Studies

2 other studies available for carprofen and Anastomotic Leak

ArticleYear
Perioperative pain relief by a COX-2 inhibitor affects ileal repair and provides a model for anastomotic leakage in the intestine.
    Surgical innovation, 2013, Volume: 20, Issue:2

    Topics: Analgesics, Opioid; Anastomotic Leak; Animals; Buprenorphine; Carbazoles; Collagen; Cyclooxygenase 2

2013
Carprofen for perioperative analgesia causes early anastomotic leakage in the rat ileum.
    BMC veterinary research, 2012, Dec-27, Volume: 8

    Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazole

2012