Compounds > carnosine
Page last updated: 2024-08-21

carnosine and Disease Models, Animal

carnosine has been researched along with Disease Models, Animal in 88 studies

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (9.09)18.2507
2000's16 (18.18)29.6817
2010's48 (54.55)24.3611
2020's16 (18.18)2.80

Authors

AuthorsStudies
Juskova, M; Milackova, I; Snirc, V; Stefek, M; Triantos, N; Tsantili-Kakoulidou, A1
Guo, Y; Hiep, NT; Hong, S; Hwang, BY; Kim, DW; Kwon, J; Lee, D; Lee, HJ; Mar, W1
Basaklar, AC; Gulbahar, O; Karabulut, R; Ozbayoglu, A; Poyraz, A; Sonmez, K; Turkyilmaz, Z1
Liang, X; Liu, ZY; Ru Li, M; Teng, N; Xie, WB; Zhang, ZQ1
Choi, HS; Chun, HJ; Jeen, YT; Keum, B; Kim, CD; Kim, ES; Lee, HS; Lee, M; Lim, JY; Ryu, HS; Seo, YS; Sul, D; Um, SH1
Hiruma, S; Kawabata, A; Kimura, T; Matsuyama, K; Moriyama, M; Murakami-Nakayama, M; Sekiguchi, F; Tsubota, M1
Byun, SJ; Chung, MJ; Lim, TJ; Lim, YJ; Seo, JG1
Kinomoto, T; Mera, Y; Minaguchi, J; Ogawa, S; Ohnishi, Y; Sawada, M; Takehana, K; Tsuge, S; Washizuka, M; Yamaguchi, T1
Ko, JK; Leung, CC1
Kudo, T; Masuo, T; Mori, M; Okamura, S; Zhang, Y1
Takei, M1
Iishi, H; Iseki, K; Ishiguro, S; Ishihara, R; Mikuni, T; Narahara, H; Sakai, N; Tatsuta, M; Uedo, N; Yano, H1
Asaka, M; Iwanaga, T; Kato, K; Kato, M; Miyashita, K; Ohkawara, T; Takeda, H1
Hatakeyama, N; Horikawa, Y; Jin, M; Matsuhashi, T; Odashima, M; Ohba, R; Otaka, M; Oyake, J; Wada, I; Watanabe, S1
Kumagai, N; Morinaga, S; Sugino, H; Takeuchi, O; Toda, K; Tsuchimoto, K; Tsunematsu, S; Watanabe, S1
Furuta, S; Itabashi, T; Miwa, M; Sano, H; Toyama, S; Yoneta, T1
Kishi, S; Segawa, Y; Yamaguchi, M1
Kato, S; Konaka, A; Nishiwaki, H; Takeuchi, K1
Ishii, H; Kai, A; Miura, S; Miyazawa, M; Mori, M; Seto, K; Suematsu, M; Suzuki, H; Yoneta, T1
Aita, H; Chaki, K; Hori, Y; Morita, H; Seiki, M; Tagashira, E; Takemasa, T; Ueki, S; Yoneta, T1
Aita, H; Chaki, K; Hori, Y; Morita, H; Seiki, M; Seto, K; Tagashira, E; Takemasa, T; Yamada, H; Yoneta, T1
Hoshi, T; Ozaki, K; Yamaguchi, M1
Ebrahim, HA; Elsherbini, DMA1
Blancquaert, L; Derave, W; Eijnde, BO; Keytsman, C; Nieste, I; Spaas, J; Van Noten, P1
Abdelkader, H; Alany, RG; Fathalla, Z; Moharram, H; Mustafa, WW; Sabry, AM1
Caruso, G1
Heo, H; Kim, HG; Park, SW; Sung, MS1
Farshad, O; Ghanbarinejad, V; Heidari, R; Ilkhaninasab, F; Khadijeh, M; Moezi, L; Mohammadi, HR; Negar, A; Ommati, MM; Zahra, M1
Ali, A; Bae, ON; Baek, SH; Battaglia, G; Cecchin, D; Doeppner, TR; Jain, SA; Kim, D; Kim, EH; Kim, ES; Kim, JK; Kim, KA; Kim, M; Majid, A; Nyberg, S; Poma, A; Redgrave, J; Shin, YJ1
Cordaro, M; Crupi, R; Cuzzocrea, S; D'amico, R; Di Paola, R; Fusco, R; Greco, V; Gugliandolo, E; Impellizzeri, D; Messina, L; Peritore, AF; Pulicetta, M; Rizzarelli, E; Schiavinato, A; Sciuto, S; Siracusa, R; Vaccaro, S1
Ali, A; Bae, ON; Baek, SH; Burrows, D; De Felice, M; Doeppner, TR; Gardner, I; Jain, S; Kim, D; Kim, ES; Kim, M; Majid, A; Redgrave, J1
Altun, S; Artas, G; Aydin, S; Bal, A; Demir, B; Kocaman, N; Kuloglu, T; Ozcan, EC; Sarac, M1
Jiang, L; Lei, L; Liu, XQ; Nie, ZY; Wang, S; Wu, YG; Yard, B; Zeng, HX; Zhang, Q; Zhang, SQ; Zhu, W1
Hisatsune, T; Lei, C; Li, H; Masuoka, N1
Aldebasi, YH; Mousa, AM1
Baker, LS; Brown, JM; Genter, MB; Seroogy, KB1
Azarova, OV; Bobrov, IP; Kalnitsky, AS; Makarova, OG; Mazko, ON; Zharikov, AY1
Casford, S; Chia, S; Dobson, CM; Habchi, J; Joshi, P; Labbadia, J; Limbocker, R; Mannini, B; Perni, M; Vendruscolo, M1
Bertoni, APS; Capalonga, L; da Silva, LR; Dal Lago, P; de Batista, D; Frizzo, MN; Heck, TG; Stefani, GP; Sulzbacher, LM; Sulzbacher, MM; Vedovatto, S; Wink, MR1
He, Q; Sun, C; Wu, Q; Zhang, X; Zhao, H1
Abd Elwahab, AH; Ramadan, BK; Schaalan, MF1
Burukoglu Donmez, D; Sahin, S1
Kato-Negishi, M; Kawahara, M; Tanaka, KI1
Bhatia, P; Jaggi, AS; Kumar, A; Singh, N; Tiwari, N1
Devyatov, AA; Fedorova, TN; Riger, NA; Ryzhkov, IN; Stvolinsky, SL; Tutelyan, VA1
Bermúdez, ML; Genter, MB; Skelton, MR1
Ahmadi-Asl, N; Mesgari-Abbasi, M; Nokhodchi, A; Vahdatpour, T; Valizadeh, H; Zakeri-Milani, P1
Bermúdez, ML; Genter, MB; Seroogy, KB1
Agarwal, A; Baba, SP; Barski, OA; Bhatnagar, A; Cai, J; Sithu, SD; Srivastava, S; Xie, Z1
Chen, Z; Li, X; Lu, Y; Ni, K; Pei, X; Ying, K; Zhang, X; Zhou, Y1
Bae, ON; Majid, A1
Aldini, G; Boldyrev, AA; Derave, W1
Duan, H; Guo, S; Jia, L; Liu, J; Zhang, H; Zhang, J; Zhang, L; Zhang, W; Zhang, Z1
Fang, J; Li, DW; Sun, BL; Yang, MF; Zhang, S; Zhang, ZY1
Bogdanowicz, P; Camaré, C; Garoby-Salom, S; Grazide, MH; Josse, G; Larroque-Cardoso, P; Nadal-Wollbold, F; Nègre-Salvayre, A; Pucelle, M; Salvayre, R; Schmitt, AM; Uchida, K; Zarkovic, K1
Adornetto, A; Bagetta, G; Cavaliere, F; Corasaniti, MT; Morrone, LA; Nucci, C; Rusciano, D; Russo, R; Varano, GP1
Liu, B; Tian, S; Wang, C; Wang, G; Wei, D; Xu, M; Xu, T; Zhang, R1
Aldini, G; Altomare, A; Cannizzaro, L; Deldicque, L; Derave, W; Gerlo, S; Hespel, P; Orioli, M; Ramaekers, M; Stegen, B; Stegen, S1
Hasanein, P; Kazemian-Mahtaj, A; Khodadadi, I1
Bevilacqua, MA; Capasso, C; Cerullo, V; Garofalo, M; Hirvinen, M; Iovine, B; Kuryk, L; Vitale, A; Yliperttula, M1
Alsheblak, MM; El-Karef, A; El-Shishtawy, MM; Elsherbiny, NM1
Bahor, Z; Davis, CK; Laud, PJ; Majid, A; Rajanikant, GK1
Kanda, Y; Kawahara, M; Niino, T; Sugizaki, T; Tamura, F; Tanaka, KI1
Albrecht, T; Aldini, G; Anna Altomare, A; Baelde, H; Braun, JD; de Heer, E; Denisi, A; Hauske, SJ; Köppel, H; Krämer, BK; Pastene, DO; Qiu, J; Regazzoni, L; Rodriguez, A; Schilperoort, M; van den Born, J; Yard, BA; Zhang, S1
Bağirici, F; Kozan, R; Sefil, F1
Babizhayev, MA; Guiotto, A; Kasus-Jacobi, A1
Chen, HL; Hang, CH; Lin, YX; Lu, H; Shi, JX; Yin, HX; Zhang, DM1
Fuchs, B; Gaunitz, F; Gebhardt, R; Geiger, KD; Hengstler, J; Hermes, M; Meixensberger, J; Renner, C; Zemitzsch, N1
Babizhayev, MA; Yegorov, YE1
Bauerova, K; Boldyrev, A; Drafi, F; Hrabarova, E; Juranek, I; Mihalova, D; Ponist, S; Soltes, L; Valachova, K1
Cheng, X; Jia, L; Luan, B; Song, L; Xu, F; Yang, Y; Zhang, X; Zhang, Z1
Brismar, K; Forsberg, E; Gross, ML; Peters, V; Schmitt, CP; Zschocke, J1
Bakker, SJ; Braunagel, M; Brinkkötter, P; Deinzer, M; Hammes, HP; Henning, RH; Koeppel, H; Krämer, BK; Navis, G; Pfister, F; Riedl, E; Sternik, P; van den Born, J; Yard, B1
Deinzer, M; Feng, Y; Hammes, HP; Harmsen, MC; Molema, G; Pfister, F; Riedl, E; vom Hagen, F; Wang, Q; Yard, B1
Ansurudeen, I; Brismar, K; Catrina, SB; Forsberg, EA; Grünler, J; Peters, V; Schmitt, CP; Sunkari, VG1
Chen, Z; Hou, WW; Hu, WW; Huang, SW; Jin, L; Ma, J; Sun, Y; Wang, Y; Xiong, JY; Yan, HJ1
Herculano, B; Hisatsune, T; Kutsuna, N; Ohba, A; Shimatani, M; Tamura, M1
Burukoğlu, D; Oter, S; Sahin, S; Sutken, E1
Ignacio, S; Lee, NM; Moore, DH; Smith, AP1
Endoh, A; Goto, T; Kataoka, E; Mikami, K; Miura, K; Odashima, M; Ohshima, S; Otaka, M; Sato, M; Sato, W; Segawa, D; Shibuya, T; Takeuchi, S; Watanabe, D; Watanabe, S; Yoneyama, K; Yoshino, R1
Arumugam, TV; Calderan, A; Chan, SL; Cutler, RG; Guiotto, A; Jo, DG; Magnus, T; Mattson, MP; Mughal, MR; Nassar, M; Ouyang, X; Ruzza, P; Tang, SC; Telljohann, RS1
Braun, GS; Deinzer, M; Floege, J; Gretz, N; Kriz, W; Moeller, MJ; Neumaier, M; Sauerhöfer, S; van der Woude, F; Yuan, G1
Chen, AF; Frenkel, MB; Gupta, R; Majid, A; Rajanikant, GK; Senut, MC; Zemke, D1
Bickford, PC; Borlongan, CV; Hara, K; Maki, M; Masuda, T; Sanberg, CD; Sanberg, PR; Yasuhara, T1
Bonaventure, N; Daune-Anglard, G; Seiler, N1
Boldyrev, AA; Dobrota, D; Kukley, ML; Matejovicova, M; Stvolinsky, SL; Tkac, I1
el-Ansary, AK; Mohamed, AM; Soliman, KM1
Abdel Aziz, M; Abdel-Sattar, S; El-Ansary, A; Nassar, YH; Soliman, KM1

Reviews

7 review(s) available for carnosine and Disease Models, Animal

ArticleYear
[Development of polaprezinc research].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012, Volume: 132, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Carnosine; Cell Division; Disease Models, Animal; Free Radical Scavengers; Humans; Organometallic Compounds; Rats; Taste Buds; Taste Disorders; Tongue; Zinc; Zinc Compounds

2012
Unveiling the Hidden Therapeutic Potential of Carnosine, a Molecule with a Multimodal Mechanism of Action: A Position Paper.
    Molecules (Basel, Switzerland), 2022, May-20, Volume: 27, Issue:10

    Topics: Animals; Brain; Carnosine; Dietary Supplements; Disease Models, Animal

2022
Influence of Imidazole-Dipeptides on Cognitive Status and Preservation in Elders: A Narrative Review.
    Nutrients, 2021, Jan-27, Volume: 13, Issue:2

    Topics: Aged; Alzheimer Disease; Animals; Anserine; Brain; Carnosine; Cognition; Cognitive Dysfunction; Dietary Supplements; Dipeptides; Disease Models, Animal; Humans; Imidazoles; Randomized Controlled Trials as Topic

2021
Zinc, Carnosine, and Neurodegenerative Diseases.
    Nutrients, 2018, Jan-29, Volume: 10, Issue:2

    Topics: Alzheimer Disease; Amyloidogenic Proteins; Animals; Antioxidants; Brain; Carnosine; Chelating Agents; Dementia, Vascular; Dietary Supplements; Disease Models, Animal; Homeostasis; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Prion Diseases; Zinc

2018
Physiology and pathophysiology of carnosine.
    Physiological reviews, 2013, Volume: 93, Issue:4

    Topics: Animals; Brain; Cardiovascular Physiological Phenomena; Carnosine; Dipeptidases; Disease Models, Animal; Female; Humans; Male; Muscle, Skeletal

2013
Systematic review and stratified meta-analysis of the efficacy of carnosine in animal models of ischemic stroke.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2016, Volume: 36, Issue:10

    Topics: Animals; Brain Ischemia; Carnosine; Disease Models, Animal; Neuroprotective Agents; Stroke; Time-to-Treatment; Treatment Outcome

2016
Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine therapy.
    Frontiers in bioscience (Landmark edition), 2010, 06-01, Volume: 15, Issue:3

    Topics: Aged; Animals; Carnosine; Cataract; Disease Models, Animal; Humans; Lens, Crystalline; Telomere; Vision, Ocular; Visual Acuity

2010

Trials

1 trial(s) available for carnosine and Disease Models, Animal

ArticleYear
N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications.
    Journal of drug targeting, 2009, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Aldehydes; Aminooxyacetic Acid; Animals; Biological Availability; Carnosine; Cataract; Cornea; Cross-Over Studies; Diabetes Complications; Disease Models, Animal; Drug Administration Schedule; Drug Delivery Systems; Drug Synergism; Female; Glycosylation; Histidine; Humans; Hydrazines; Lubricants; Male; Middle Aged; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Ophthalmoscopy; Rabbits

2009

Other Studies

80 other study(ies) available for carnosine and Disease Models, Animal

ArticleYear
(2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.
    Bioorganic & medicinal chemistry, 2011, Dec-01, Volume: 19, Issue:23

    Topics: Acetates; Aldehyde Reductase; Animals; Antioxidants; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Male; Rats; Rats, Wistar; Sorbitol

2011
Chemical Constituents Isolated from the Root Bark of Cudrania tricuspidata and Their Potential Neuroprotective Effects.
    Journal of natural products, 2016, 08-26, Volume: 79, Issue:8

    Topics: Animals; Cell Death; Disease Models, Animal; Glucose; Ischemia; Moraceae; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Plant Bark; Plant Roots; Republic of Korea; Xanthones

2016
Effect of polaprezinc on experimental corrosive esophageal burns in rats.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2017, Nov-01, Volume: 30, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Apoptosis; Burns, Chemical; Carnosine; Caustics; Disease Models, Animal; Esophageal Stenosis; Esophagus; Organometallic Compounds; Rats; Rats, Wistar; Zinc Compounds

2017
Effects of polaprezinc on gastric mucosal damage and neurotransmitters in a rat model of chemotherapy-induced vomiting.
    The Journal of international medical research, 2018, Volume: 46, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents; Brain; Brain Chemistry; Carnosine; Cisplatin; Cyclophosphamide; Disease Models, Animal; Dopamine; Gastric Mucosa; Intestinal Mucosa; Intestine, Small; Male; Neurotransmitter Agents; NF-kappa B; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Serotonin; Vomiting; Zinc Compounds

2018
The effect of polaprezinc on gastric mucosal protection in rats with ethanol-induced gastric mucosal damage: comparison study with rebamipide.
    Life sciences, 2013, Jul-30, Volume: 93, Issue:2-3

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Carnosine; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Glutathione Transferase; Heat-Shock Proteins; Heme Oxygenase-1; Male; Organometallic Compounds; Peroxiredoxins; Quinolones; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Superoxide Dismutase; Superoxide Dismutase-1; Vascular Endothelial Growth Factor A; Zinc Compounds

2013
Polaprezinc attenuates cyclophosphamide-induced cystitis and related bladder pain in mice.
    Journal of pharmacological sciences, 2015, Volume: 127, Issue:2

    Topics: Administration, Ophthalmic; Animals; Anti-Ulcer Agents; Antioxidants; Calcium Channels, T-Type; Carnosine; Cyclophosphamide; Cystitis, Interstitial; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Mice, Inbred Strains; Organometallic Compounds; Urinary Bladder; Zinc Compounds

2015
In vivo effects of s-pantoprazole, polaprenzinc, and probiotic blend on chronic small intestinal injury induced by indomethacin.
    Beneficial microbes, 2016, Nov-30, Volume: 7, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bifidobacterium; Body Weight; Carnosine; Chronic Disease; Cytokines; Disease Models, Animal; Eating; Gram-Negative Bacteria; Indomethacin; Intestine, Small; Lactobacillus; Male; Organometallic Compounds; Pantoprazole; Probiotics; Random Allocation; Rats; Rats, Sprague-Dawley; Zinc Compounds

2016
Effects of polaprezinc on morphological change of the tongue in zinc-deficient rats.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2010, Volume: 39, Issue:8

    Topics: Animals; Carnosine; Cell Count; Cell Cycle; Cell Proliferation; Disease Models, Animal; Epithelium; Leukoplakia, Oral; Male; Microscopy, Electron, Scanning; Microvilli; Organometallic Compounds; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Taste Buds; Taste Disorders; Time Factors; Tongue; Trace Elements; Zinc; Zinc Compounds

2010
Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:12

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Antioxidants; Carnosine; Chemokines; Cytokines; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Male; Organometallic Compounds; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach; Stomach Ulcer; Time Factors; Wound Healing; Zinc Compounds; Zingiber officinale

2010
Calcineurin inhibition by polaprezinc in rats with experimentally-induced colitis.
    Life sciences, 2011, Feb-28, Volume: 88, Issue:9-10

    Topics: Administration, Rectal; Animals; Anti-Ulcer Agents; Calcineurin; Calcineurin Inhibitors; Carnosine; Cell Survival; Colitis; Cytokines; Disease Models, Animal; Gene Expression; Humans; Interleukin-2; Intestinal Mucosa; Jurkat Cells; Male; NFATC Transcription Factors; Organometallic Compounds; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Trinitrobenzenesulfonic Acid; Zinc Compounds

2011
Polaprezinc attenuates Helicobacter pylori-associated gastritis in Mongolian gerbils.
    Helicobacter, 2002, Volume: 7, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Carnosine; Chloramines; Disease Models, Animal; Gastric Mucosa; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Organometallic Compounds; Spectrophotometry; Zinc; Zinc Compounds

2002
Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:11

    Topics: Analysis of Variance; Animals; Anti-Ulcer Agents; Biopsy, Needle; Carnosine; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Heat-Shock Proteins; Immunohistochemistry; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Organometallic Compounds; Peroxidase; Probability; Random Allocation; Reference Values; Sensitivity and Specificity; Zinc Compounds

2005
Zinc L-carnosine protects colonic mucosal injury through induction of heat shock protein 72 and suppression of NF-kappaB activation.
    Life sciences, 2006, Nov-10, Volume: 79, Issue:24

    Topics: Acetic Acid; Administration, Rectal; Animals; Anti-Ulcer Agents; Blotting, Western; Carnosine; Colon; Disease Models, Animal; HSP72 Heat-Shock Proteins; Intestinal Mucosa; Male; NF-kappa B; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Zinc; Zinc Compounds

2006
Polaprezinc attenuates liver fibrosis in a mouse model of non-alcoholic steatohepatitis.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:12

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Carnosine; Choline Deficiency; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Hepatic Stellate Cells; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Methionine; Mice; Mice, Inbred C57BL; Organometallic Compounds; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1; Triglycerides; Tumor Necrosis Factor-alpha; Zinc Compounds

2008
Residence time of polaprezinc (zinc L-carnosine complex) in the rat stomach and adhesiveness to ulcerous sites.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Binding Sites; Carbon Isotopes; Carnosine; Disease Models, Animal; Gastric Emptying; Gastric Mucosa; Gastrointestinal Contents; Isotope Labeling; Male; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Stomach Ulcer; Sulfates; Zinc; Zinc Compounds; Zinc Radioisotopes; Zinc Sulfate

1995
Histomorphological confirmation of the preventive effect of beta-alanyl-L-histidinato zinc on bone loss in ovariectomized rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:6

    Topics: Administration, Oral; Animals; Bone Density; Carnosine; Dipeptides; Disease Models, Animal; Estradiol; Female; Femur; Humans; Organometallic Compounds; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Wistar; Zinc; Zinc Compounds

1994
Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:10

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Ulcer Agents; Carnosine; Chloramines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Gastric Mucosa; Male; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sucralfate; Zinc; Zinc Compounds

1997
Polaprezinc attenuates the Helicobacter pylori-induced gastric mucosal leucocyte activation in Mongolian gerbils--a study using intravital videomicroscopy.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Carnosine; Disease Models, Animal; Gastric Mucosa; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Inflammation; Leukocytes; Male; Organometallic Compounds; Oxidation-Reduction; Zinc Compounds

2001
[Effect of Z-103 on wound healing by dermal incision in guinea pigs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Disease Models, Animal; Guinea Pigs; Hydroxyproline; Male; Neovascularization, Pathologic; Organometallic Compounds; Skin; Tensile Strength; Wound Healing; Zinc Compounds

1992
[Studies on the healing promoting action of Z-103 in chronic gastric ulcer models of rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Carnosine; Dipeptides; Disease Models, Animal; DNA; Hydroxyproline; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Stomach Ulcer; Wound Healing; Zinc; Zinc Compounds

1992
Beta-alanyl-L-histidinato zinc prevents skeletal unloading-induced disorder of bone metabolism in rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1990, Volume: 190, Issue:4

    Topics: Alkaline Phosphatase; Animals; Bone Diseases, Metabolic; Calcium; Carnosine; Dipeptides; Disease Models, Animal; DNA; Immobilization; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Zinc; Zinc Compounds

1990
Renovation of Intestinal Barrier by Polydatin in Experimentally Induced Ulcerative Colitis: Comparative Ultrastructural Study with L-Carnosine.
    Cells, tissues, organs, 2021, Volume: 210, Issue:4

    Topics: Animals; Carnosine; Colitis, Ulcerative; Colon; Disease Models, Animal; Glucosides; Humans; Rats; Stilbenes

2021
Carnosine and skeletal muscle dysfunction in a rodent multiple sclerosis model.
    Amino acids, 2021, Volume: 53, Issue:11

    Topics: Animals; Carnosine; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Mice, Inbred C57BL; Multiple Sclerosis; Muscle Contraction; Muscle, Skeletal

2021
Hybrid thermosensitive-mucoadhesive
    Drug delivery, 2022, Volume: 29, Issue:1

    Topics: Administration, Topical; Animals; Carnosine; Chemistry, Pharmaceutical; Chitosan; Cornea; Corneal Ulcer; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Liberation; Gels; Methylcellulose; Poloxamer; Rabbits; Rheology; Temperature; Wound Healing

2022
Carnosine decreases retinal ganglion cell death in a mouse model of optic nerve crushing.
    Neuroscience letters, 2019, 10-15, Volume: 711

    Topics: Animals; Apoptosis; Carnosine; Disease Models, Animal; Mice; Mice, Inbred C57BL; Nerve Crush; Neuroprotective Agents; Optic Nerve; Optic Nerve Injuries; Oxidative Stress; Retinal Ganglion Cells

2019
The Nephroprotective Role of Carnosine Against Ifosfamide-Induced Renal Injury and Electrolytes Imbalance is Mediated Via the Regulation of Mitochondrial Function and Alleviation of Oxidative Stress.
    Drug research, 2020, Volume: 70, Issue:1

    Topics: Acute Kidney Injury; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Carnosine; Disease Models, Animal; Humans; Ifosfamide; Injections, Intraperitoneal; Kidney; Lipid Peroxidation; Male; Mitochondria; Oxidative Stress; Rats; Reactive Oxygen Species

2020
LRP-1 functionalized polymersomes enhance the efficacy of carnosine in experimental stroke.
    Scientific reports, 2020, 01-20, Volume: 10, Issue:1

    Topics: Animals; Brain Chemistry; Brain Ischemia; Carnosine; Disease Models, Animal; Drug Carriers; Drug Compounding; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice; Peptides; Rats; Stroke; Time Factors; Treatment Outcome

2020
Protective effect of a new hyaluronic acid -carnosine conjugate on the modulation of the inflammatory response in mice subjected to collagen-induced arthritis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 125

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Biomarkers; Carnosine; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Gene Expression; Hyaluronic Acid; Immunohistochemistry; Inflammation Mediators; Male; Mice; Nitric Oxide Synthase Type II; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Protective Agents; Radiography

2020
Comparative Cerebroprotective Potential of d- and l-Carnosine Following Ischemic Stroke in Mice.
    International journal of molecular sciences, 2020, Apr-26, Volume: 21, Issue:9

    Topics: Animals; Brain Chemistry; Carnosine; Cells, Cultured; Disease Models, Animal; Humans; Injections, Intravenous; Ischemic Stroke; Male; Mice; Neurons; Neuroprotective Agents; Primary Cell Culture

2020
Effects of Carnosine, Ankaferd, and Silver Sulfadiazine on an Experimental Burn Model: Roles of Irisin and HSP70.
    Journal of burn care & research : official publication of the American Burn Association, 2021, 05-07, Volume: 42, Issue:3

    Topics: Administration, Topical; Animals; Burns; Carnosine; Disease Models, Animal; Fibronectins; HSP70 Heat-Shock Proteins; Male; Plant Extracts; Rats; Silver Sulfadiazine; Wound Healing

2021
Carnosine alleviates diabetic nephropathy by targeting GNMT, a key enzyme mediating renal inflammation and fibrosis.
    Clinical science (London, England : 1979), 2020, 12-11, Volume: 134, Issue:23

    Topics: Adult; Animals; Apoptosis; Biomarkers; Carnosine; Cell Survival; Cytoprotection; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Epithelial Cells; Extracellular Matrix; Female; Fibrosis; Glucose; Glycine N-Methyltransferase; Humans; Inflammation; Kidney; Male; Mice, Inbred C57BL; Middle Aged; Molecular Targeted Therapy; Streptozocin

2020
L-carnosine mitigates interleukin-1α-induced dry eye disease in rabbits via its antioxidant, anti-inflammatory, antiapoptotic, and antifibrotic effects.
    Cutaneous and ocular toxicology, 2021, Volume: 40, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Carnosine; Disease Models, Animal; Dry Eye Syndromes; Humans; Interleukin-1alpha; Lacrimal Apparatus; Male; Oxidative Stress; Rabbits; Recombinant Proteins

2021
Intranasal Carnosine Mitigates α-Synuclein Pathology and Motor Dysfunction in the Thy1-aSyn Mouse Model of Parkinson's Disease.
    ACS chemical neuroscience, 2021, 07-07, Volume: 12, Issue:13

    Topics: alpha-Synuclein; Animals; Carnosine; Disease Models, Animal; Mice; Mice, Transgenic; Parkinson Disease

2021
Effect of Carnosine on the Course of Experimental Urate Nephrolithiasis.
    Bulletin of experimental biology and medicine, 2021, Volume: 171, Issue:2

    Topics: Animals; Antioxidants; Carnosine; Disease Models, Animal; Disease Progression; Free Radicals; Kidney; Male; Nephrolithiasis; Oxidative Stress; Rats; Rats, Wistar; Uric Acid

2021
Two human metabolites rescue a C. elegans model of Alzheimer's disease via a cytosolic unfolded protein response.
    Communications biology, 2021, 07-07, Volume: 4, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carnosine; Cytosol; Disease Models, Animal; HSP40 Heat-Shock Proteins; Humans; Kynurenic Acid; Protein Aggregates; Protein Aggregation, Pathological; Transcription Factors; Unfolded Protein Response

2021
Effects of aerobic and resistance exercise training associated with carnosine precursor supplementation on maximal strength and V̇O
    Life sciences, 2021, Oct-01, Volume: 282

    Topics: Animals; beta-Alanine; Carnosine; Disease Models, Animal; Heart Failure; Histidine; Male; Oxygen; Physical Conditioning, Animal; Rats; Rats, Wistar

2021
Mechanistic Evaluation of the Protective Effect of Carnosine on Acute Lung Injury in Sepsis Rats.
    Pharmacology, 2017, Volume: 100, Issue:5-6

    Topics: Acute Lung Injury; Animals; Antioxidants; Carnosine; Catalase; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Interleukin-8; Lipid Peroxidation; Lung; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2017
Synergistic effect of carnosine on browning of adipose tissue in exercised obese rats; a focus on circulating irisin levels.
    Journal of cellular physiology, 2018, Volume: 233, Issue:6

    Topics: Adipose Tissue, Brown; Adiposity; Animals; Anti-Inflammatory Agents; Anti-Obesity Agents; Antioxidants; Biomarkers; Carnosine; Combined Modality Therapy; Disease Models, Animal; Energy Metabolism; Exercise Therapy; Fibronectins; Inflammation Mediators; Lipids; Male; Obesity; Oxidative Stress; Phenotype; Rats, Wistar; Signal Transduction

2018
Effects of Carnosine (Beta-Alanyl-L-Histidine) in an Experimental Rat Model of Acute Kidney Injury Due to Septic Shock.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Jan-15, Volume: 24

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Carnosine; Cecum; Disease Models, Animal; Kidney; Male; Punctures; Rats; Rats, Sprague-Dawley; Sepsis; Shock, Septic

2018
Potential of carnosine, a histamine precursor in rat model of bilateral common carotid artery occlusion-induced vascular dementia.
    Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:5

    Topics: Animals; Carnosine; Carotid Artery, Common; Carotid Stenosis; Dementia, Vascular; Disease Models, Animal; Female; Male; Maze Learning; Neuroprotective Agents; Rats; Rats, Wistar

2018
[Study of the neuroprotective effects of carnosine in an experimental model of focal cerebral ischemia/reperfusion].
    Biomeditsinskaia khimiia, 2018, Volume: 64, Issue:4

    Topics: Animals; Antioxidants; Brain Ischemia; Carnosine; Disease Models, Animal; Male; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Reperfusion Injury

2018
Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease.
    Molecular genetics and metabolism, 2018, Volume: 125, Issue:3

    Topics: Administration, Intranasal; alpha-Synuclein; Animals; Carnosine; Corpus Striatum; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Mitochondria; Parkinson Disease; Thy-1 Antigens; Transcriptome

2018
Leucine-glycine and carnosine dipeptides prevent diabetes induced by multiple low-doses of streptozotocin in an experimental model of adult mice.
    Journal of diabetes investigation, 2019, Volume: 10, Issue:5

    Topics: Animals; Carnosine; Diabetes Mellitus, Experimental; Dipeptides; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C

2019
Evaluation of Carnosine Intervention in the Thy1-aSyn Mouse Model of Parkinson's Disease.
    Neuroscience, 2019, 07-15, Volume: 411

    Topics: alpha-Synuclein; Animals; Carnosine; Disease Models, Animal; Mice; Mice, Transgenic; Motor Activity; Parkinson Disease; Smell; Treatment Outcome

2019
Dietary carnosine prevents early atherosclerotic lesion formation in apolipoprotein E-null mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:6

    Topics: Aldehydes; Animals; Apolipoproteins E; Atherosclerosis; Carnosine; Dietary Supplements; Disease Models, Animal; Lipid Peroxidation; Lipoproteins, LDL; Mice; Mice, Knockout; Random Allocation; Reference Values

2013
[Protective effects of carnosine against closed head injury in mice].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2013, Volume: 42, Issue:3

    Topics: Animals; Carnosine; Disease Models, Animal; Head Injuries, Closed; Male; Mice; Mice, Inbred ICR

2013
Role of histidine/histamine in carnosine-induced neuroprotection during ischemic brain damage.
    Brain research, 2013, Aug-21, Volume: 1527

    Topics: Animals; Astrocytes; Brain Ischemia; Carnosine; Disease Models, Animal; Histamine; Histidine; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2013
Treatment with carnosine reduces hypoxia-ischemia brain damage in a neonatal rat model.
    European journal of pharmacology, 2014, Mar-15, Volume: 727

    Topics: Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Biomarkers; Brain; Carnosine; Cognition; Disease Models, Animal; Hypoxia-Ischemia, Brain; Injections, Intraperitoneal; Maze Learning; Memory; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Time Factors

2014
Carnosine attenuates early brain injury through its antioxidative and anti-apoptotic effects in a rat experimental subarachnoid hemorrhage model.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:2

    Topics: Animals; Antigens, Nuclear; Antioxidants; Apoptosis; Behavior, Animal; Blood-Brain Barrier; Brain Edema; Brain Injuries; Carnosine; Caspase 3; Cerebral Cortex; Cytokines; Disease Models, Animal; DNA; Fluorescent Antibody Technique; Glutathione Peroxidase; In Situ Nick-End Labeling; Lipids; Male; Microglia; Nerve Tissue Proteins; Oxidation-Reduction; Permeability; Rats, Sprague-Dawley; Reactive Oxygen Species; Subarachnoid Hemorrhage; Superoxide Dismutase

2015
Elastin Modification by 4-Hydroxynonenal in Hairless Mice Exposed to UV-A. Role in Photoaging and Actinic Elastosis.
    The Journal of investigative dermatology, 2015, Volume: 135, Issue:7

    Topics: Aldehydes; Animals; Carnosine; Disease Models, Animal; Elasticity; Elastin; Lipid Peroxidation; Mice; Mice, Hairless; Oxidative Stress; Photosensitivity Disorders; Random Allocation; Sensitivity and Specificity; Skin Aging; Ultraviolet Rays

2015
Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury.
    Molecular vision, 2015, Volume: 21

    Topics: Animals; Carnosine; Cell Survival; Colforsin; Disease Models, Animal; Drug Synergism; Glaucoma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Intraocular Pressure; Intravitreal Injections; Ischemia; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Retinal Ganglion Cells; Retinal Vessels; Signal Transduction; Taurine

2015
Carnosine markedly ameliorates H9N2 swine influenza virus-induced acute lung injury.
    The Journal of general virology, 2015, Volume: 96, Issue:10

    Topics: Acute Lung Injury; Administration, Oral; Animals; Antioxidants; Carnosine; Disease Models, Animal; Female; Histocytochemistry; Influenza A Virus, H9N2 Subtype; Lung; Mice, Inbred BALB C; Orthomyxoviridae Infections; Survival Analysis; Time Factors; Treatment Outcome

2015
Plasma carnosine, but not muscle carnosine, attenuates high-fat diet-induced metabolic stress.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2015, Volume: 40, Issue:9

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; beta-Alanine; Blood Glucose; Carnosine; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Inflammation; Inflammation Mediators; Insulin; Insulin Resistance; Lipid Peroxidation; Male; Muscle, Skeletal; Nitric Oxide Synthase Type II; Rats, Sprague-Dawley; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Bioactive peptide carnosin protects against lead acetate-induced hepatotoxicity by abrogation of oxidative stress in rats.
    Pharmaceutical biology, 2016, Volume: 54, Issue:8

    Topics: Animals; Antioxidants; Biomarkers; Body Weight; Carnosine; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Lipid Peroxidation; Liver; Male; Organ Size; Organometallic Compounds; Oxidative Stress; Rats, Wistar

2016
Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:4

    Topics: Adenoviridae; Animals; Apoptosis; Autophagy; Carnosine; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; HSP27 Heat-Shock Proteins; Humans; Interleukin-8; Mice; Neoplasms; Oncolytic Virotherapy; Oncolytic Viruses; Transduction, Genetic; Tumor Burden; Virus Replication; Xenograft Model Antitumor Assays

2016
Protective effects of L-carnosine on CCl4 -induced hepatic injury in rats.
    European cytokine network, 2016, Mar-01, Volume: 27, Issue:1

    Topics: Actins; Animals; Biomarkers; Carbon Tetrachloride; Carnosine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression; Inflammation; Liver Cirrhosis; Liver Function Tests; Male; Models, Biological; NF-E2-Related Factor 2; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protective Agents; Rats; Superoxide Dismutase

2016
Preventive Effects of Carnosine on Lipopolysaccharide-induced Lung Injury.
    Scientific reports, 2017, 02-16, Volume: 7

    Topics: Animals; Carnosine; Disease Models, Animal; Endoplasmic Reticulum Stress; Lipopolysaccharides; Male; Mice; Oxidative Stress; Reactive Oxygen Species; Respiratory Distress Syndrome

2017
Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.
    Scientific reports, 2017, 03-10, Volume: 7

    Topics: Administration, Oral; Albuminuria; Animals; Blood Glucose; C-Peptide; Carnosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Gene Expression; Glomerular Mesangium; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Kidney Glomerulus; Male; Mice; Mice, Obese; Organ Size

2017
Anticonvulsant effect of carnosine on penicillin-induced epileptiform activity in rats.
    Brain research, 2008, Nov-06, Volume: 1239

    Topics: Animals; Anticonvulsants; Brain; Carnosine; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Male; Rats; Rats, Wistar; Time Factors

2008
N-acetylcysteine suppresses oxidative stress in experimental rats with subarachnoid hemorrhage.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:5

    Topics: Analysis of Variance; Animals; Brain Edema; Carnosine; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Nervous System Diseases; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Superoxide Dismutase

2009
Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model.
    Molecular cancer, 2010, Jan-06, Volume: 9

    Topics: Adenosine Triphosphate; Animals; Carnosine; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Injections, Intraperitoneal; Mice; Mice, Nude; Mitosis; Neoplasms; NIH 3T3 Cells; Oxidoreductases; Receptor, ErbB-2

2010
Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo.
    Neuro endocrinology letters, 2010, Volume: 31 Suppl 2

    Topics: Animals; Antioxidants; Antirheumatic Agents; Arthritis, Experimental; Carnosine; Disease Models, Animal; Free Radicals; Glutathione; Hyaluronic Acid; In Vitro Techniques; Male; Methotrexate; Oxidation-Reduction; Protein Carbonylation; Rats; Rats, Inbred Lew; Thiobarbituric Acid Reactive Substances

2010
Carnosine pretreatment protects against hypoxia-ischemia brain damage in the neonatal rat model.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Brain; Brain Infarction; Carnosine; Caspase 3; Disease Models, Animal; Female; Gene Expression Regulation; Hypoxia-Ischemia, Brain; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spatial Behavior; Survival Analysis; Time Factors

2011
Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice.
    Amino acids, 2012, Volume: 42, Issue:6

    Topics: Age Factors; Animals; Animals, Genetically Modified; Anserine; Capillary Permeability; Carnosine; Diabetes Mellitus; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Humans; Kidney; Mice; Proteinuria

2012
Carnosine prevents apoptosis of glomerular cells and podocyte loss in STZ diabetic rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:2

    Topics: Acetylglucosamine; Administration, Oral; Animals; Apoptosis; bcl-2-Associated X Protein; Carnosine; Cytochromes c; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Kidney Glomerulus; Oxidative Stress; Podocytes; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin

2011
Oral carnosine supplementation prevents vascular damage in experimental diabetic retinopathy.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:1

    Topics: Administration, Oral; Angiopoietin-2; Animals; Antioxidants; Carnosine; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Heme Oxygenase-1; HSP27 Heat-Shock Proteins; Male; Neuroglia; Oxidative Stress; Pericytes; Photoreceptor Cells, Vertebrate; Rats; Rats, Wistar; Reactive Oxygen Species; Retinal Ganglion Cells; Retinal Vessels; Streptozocin; Vascular Endothelial Growth Factor A

2011
Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes.
    Amino acids, 2012, Volume: 43, Issue:1

    Topics: Animals; Carnosine; Cell Line; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Random Allocation; Skin; Wound Healing

2012
Protective effect of carnosine on subcortical ischemic vascular dementia in mice.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:9

    Topics: Animals; Avoidance Learning; Carnosine; Corpus Callosum; Dementia, Vascular; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Histidine; Histidine Decarboxylase; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Myelin Basic Protein; Neuroprotective Agents; Reactive Oxygen Species; Recognition, Psychology

2012
β-alanyl-L-histidine rescues cognitive deficits caused by feeding a high fat diet in a transgenic mouse model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 33, Issue:4

    Topics: Alzheimer Disease; Animals; Carnosine; Cognition Disorders; Diet, High-Fat; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Transgenic

2013
The effects of carnosine in an experimental rat model of septic shock.
    Medical science monitor basic research, 2013, Feb-07, Volume: 19

    Topics: Animals; Body Weight; Carnosine; Disease Models, Animal; Female; Liver; Male; Rats; Rats, Sprague-Dawley; Shock, Septic

2013
Effect of neuroprotective drugs on gene expression in G93A/SOD1 mice.
    Annals of the New York Academy of Sciences, 2005, Volume: 1053

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Apoptosis; Carnosine; Disease Models, Animal; Drug Evaluation, Preclinical; Flavanones; Gene Expression; Gene Expression Regulation; Genetic Markers; Inflammation; Metallothionein; Mice; Mice, Knockout; Neuroprotective Agents; Neurotoxins; Oxidative Stress; RNA; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1

2005
Zinc L-carnosine protects against mucosal injury in portal hypertensive gastropathy through induction of heat shock protein 72.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:11

    Topics: Animals; Bile Ducts; Blotting, Western; Carnosine; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; HSP72 Heat-Shock Proteins; Hypertension, Portal; Liver Cirrhosis; Male; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Zinc Sulfate

2006
Neuroprotective actions of a histidine analogue in models of ischemic stroke.
    Journal of neurochemistry, 2007, Volume: 101, Issue:3

    Topics: Animals; Animals, Newborn; Brain Infarction; Carnosine; Caspase 3; Cell Death; Cells, Cultured; Chromatography, High Pressure Liquid; Disease Models, Animal; Glucose; Histidine; Hypoxia; Infarction, Middle Cerebral Artery; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Time Factors

2007
L-carnosine, a substrate of carnosinase-1, influences glucose metabolism.
    Diabetes, 2007, Volume: 56, Issue:10

    Topics: Animals; Blood Glucose; Carnosine; Cloning, Molecular; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Genetic Predisposition to Disease; Genetic Variation; Glycated Hemoglobin; Humans; Mice; Mice, Inbred Strains; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Transfection

2007
Carnosine is neuroprotective against permanent focal cerebral ischemia in mice.
    Stroke, 2007, Volume: 38, Issue:11

    Topics: Animals; Antioxidants; Brain; Brain Ischemia; Carnosine; Cell Death; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Free Radical Scavengers; Glutathione; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Treatment Outcome

2007
Dietary supplementation exerts neuroprotective effects in ischemic stroke model.
    Rejuvenation research, 2008, Volume: 11, Issue:1

    Topics: Animals; Blueberry Plants; Brain Ischemia; Carnosine; Cell Differentiation; Cholecalciferol; Dietary Supplements; Disease Models, Animal; Doublecortin Protein; Drugs, Chinese Herbal; Male; Nervous System Diseases; Neurons; Neuroprotective Agents; Plant Extracts; Rats; Rats, Sprague-Dawley; Stroke; Tea

2008
Some biochemical and pathophysiological aspects of long-term elevation of brain ornithine concentrations.
    Pharmacology & toxicology, 1993, Volume: 73, Issue:1

    Topics: Animals; Brain; Carnosine; Chickens; Disease Models, Animal; Electroretinography; Eye; Female; gamma-Aminobutyric Acid; Gyrate Atrophy; Longitudinal Studies; Mice; Mice, Inbred C57BL; Ornithine; Ornithine-Oxo-Acid Transaminase

1993
Carnosine: an endogenous neuroprotector in the ischemic brain.
    Cellular and molecular neurobiology, 1999, Volume: 19, Issue:1

    Topics: Animals; Antioxidants; Brain; Brain Chemistry; Brain Ischemia; Carnosine; Disease Models, Animal; Electroencephalography; Lipid Peroxidation; Magnetic Resonance Imaging; Neuroprotective Agents; Rats; Reactive Oxygen Species

1999
Effect of carnosine administration on certain metabolic parameters in bilharzial infected hamsters.
    Journal of the Egyptian Society of Parasitology, 2000, Volume: 30, Issue:2

    Topics: Animals; Carnosine; Cricetinae; Disease Models, Animal; Male; Schistosomiasis mansoni

2000
Effects of carnosine on bilharzial infestation in hamsters: biochemical and histochemical studies.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2002, Volume: 131, Issue:3

    Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carnosine; Collagen Type III; Cricetinae; Disease Models, Animal; Female; gamma-Glutamyltransferase; Granuloma; Liver; Male; Mesocricetus; Schistosoma; Schistosomiasis mansoni

2002