Page last updated: 2024-08-21

carnosine and Diabetes Mellitus, Type 2

carnosine has been researched along with Diabetes Mellitus, Type 2 in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (9.68)29.6817
2010's16 (51.61)24.3611
2020's12 (38.71)2.80

Authors

AuthorsStudies
Ademi, Z; de Courten, B; Liew, D; Magliano, DJ; Menon, K; Zomer, E1
Becker, I; Eckhardt, M; Wang, Y; Wang-Eckhardt, L; Yuan, J1
Cai, YF; Chen, YB; Guan, L; Li, HY; Peng, D; Qiao, LJ; Wang, Q; Xia, Q; Zhang, SJ1
Elliott-Sale, KJ; Matthews, JJ; Sale, C; Santos, L; Turner, MD1
Lu, J; Ndolo, RO; Ren, Y; Wang, G; Yang, J; Yu, L; Zhao, X; Zhao, Y1
Cameron, J; de Courten, B; de Courten, M; Feehan, J; Hodge, A; Lu, ZX; Menon, K; Saadati, S1
Artioli, GG; Dolan, E; Elliott-Sale, KJ; Matthews, JJ; Sale, C; Santos, L; Swinton, PA; Turner, MD2
Satirapoj, B; Siriwattanasit, N; Supasyndh, O1
Baelde, H; Derave, W; Everaert, I; Hanssens, M; Stautemas, J; van Aanhold, C; Van der Stede, T; Vanhaecke, L1
Billacura, MP; Boocock, DJ; Caton, PW; Colombo, SL; Coveney, C; Doig, CL; Foulds, GA; Hanna, K; Jackisch, L; Lavilla, CJ; McTernan, PG; Miles, AK; Murphy, A; Sale, C; Sayers, SR; Tan, A; Turner, MD1
Baye, E; Cameron, J; de Courten, B; de Courten, MP; Earnest, A; Menon, K1
Aydın, AF; Bingül, İ; Doğan-Ekici, I; Doğru Abbasoğlu, S; Küçükgergin, C; Uysal, M1
Faraji, E; Houjeghani, S; Jafarabadi, MA; Kheirouri, S1
Artioli, GG; Jones, RL; Sale, C1
Anastasiadou, C; Chatzidimitriou, M; Daskalou, T; Fikioris, N; Gianakopoulos, X; Gubili, C; Karkabounas, S; Kontargiris, E; Papadopoulos, N; Peschos, D; Ragos, V; Simos, YV1
Peters, V; Schmitt, CP; Yard, B1
Büttner, M; Fleming, T; Kroll, J; Li, X; Morgenstern, J; Nawroth, PP; Peters, V; Poschet, G; Poth, T; Schmitt, CP; Schmöhl, F; Volk, N; Weigand, T1
Babizhayev, MA; Deyev, AI; Lankin, VZ; Savel'Yeva, EL; Yegorov, YE1
Federici, A; Federici, G; Milani, M2
Ansurudeen, I; Botusan, IR; Brismar, K; Catrina, SB; Forsberg, EA; Peters, V; Wang, J1
Allatif, O; Bastard, JP; Bieuvelet, S; Brochot, A; Clément, K; Cotillard, A; Fellahi, S; Guilbot, A; Langlois, C; Liu, Y; Rizkalla, SW; Stévant, M; Vatier, C1
Aldini, G; Barbaresi, S; de Courten, B; de Courten, MP; Derave, W; Garzon, D; Jakubova, M; Krssak, M; Krumpolec, P; Kukurova, IJ; Kurdiova, T; Teede, HJ; Ukropcova, B; Ukropec, J; Valkovic, L; Vallova, S1
D'Angelo, A; Derosa, G; Maffioli, P; Romano, D1
Albrecht, T; Aldini, G; Anna Altomare, A; Baelde, H; Braun, JD; de Heer, E; Denisi, A; Hauske, SJ; Köppel, H; Krämer, BK; Pastene, DO; Qiu, J; Regazzoni, L; Rodriguez, A; Schilperoort, M; van den Born, J; Yard, BA; Zhang, S1
Achten, E; Artioli, GG; Derave, W; Everaert, I; Gualano, B; Harris, R; Junior, AH; Otaduy, MC; Roschel, H; Stegen, S; Taes, Y1
Ansurudeen, I; Brismar, K; Catrina, SB; Forsberg, EA; Grünler, J; Peters, V; Schmitt, CP; Sunkari, VG1
Baelde, H; Bakker, SJ; Bartram, CR; Brinkkoetter, P; Cerna, M; de Heer, E; Fischer, C; Hammes, HP; Hohenadel, D; Janssen, B; Köppel, H; Mathieson, P; Meyer, J; Nawroth, P; Peters, V; Rind, N; Romzova, M; Rondeau, E; Rychlik, I; Saleem, MA; Sauerhoefer, S; van der Woude, FJ; Yard, BA; Zirie, M; Zschocke, J1
Bowden, DW; Freedman, BI; Hicks, PJ; Janssen, B; Langefeld, CD; McDonough, C; Pierson, ED; Rich, SS; Sale, MM; van der Woude, FJ; Xu, J; Yard, BA1
Braun, GS; Deinzer, M; Floege, J; Gretz, N; Kriz, W; Moeller, MJ; Neumaier, M; Sauerhöfer, S; van der Woude, F; Yuan, G1

Reviews

4 review(s) available for carnosine and Diabetes Mellitus, Type 2

ArticleYear
Effect of Carnosine or β-Alanine Supplementation on Markers of Glycemic Control and Insulin Resistance in Humans and Animals: A Systematic Review and Meta-analysis.
    Advances in nutrition (Bethesda, Md.), 2021, 12-01, Volume: 12, Issue:6

    Topics: Animals; Bayes Theorem; beta-Alanine; Blood Glucose; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Glycemic Control; Humans; Insulin; Insulin Resistance

2021
Carnosine in health and disease.
    European journal of sport science, 2019, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Aging; Brain; Carnosine; Cognition; Diabetes Mellitus, Type 2; Heart; Humans; Kidney; Muscle, Skeletal; Neoplasms; Neurodegenerative Diseases; Pancreas; Performance-Enhancing Substances

2019
Carnosine and Diabetic Nephropathy.
    Current medicinal chemistry, 2020, Volume: 27, Issue:11

    Topics: Carnosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Humans; Kidney

2020
Diabetes mellitus: novel insights, analysis and interpretation of pathophysiology and complications management with imidazole-containing peptidomimetic antioxidants.
    Recent patents on drug delivery & formulation, 2013, Volume: 7, Issue:3

    Topics: Animals; Antioxidants; Carnosine; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Design; Humans; Hyperglycemia; Imidazoles; Patents as Topic; Peptidomimetics

2013

Trials

11 trial(s) available for carnosine and Diabetes Mellitus, Type 2

ArticleYear
Carnosine Did Not Affect Vascular and Metabolic Outcomes in Patients with Prediabetes and Type 2 Diabetes: A 14-Week Randomized Controlled Trial.
    Nutrients, 2023, Nov-19, Volume: 15, Issue:22

    Topics: Adult; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Humans; Lipids; Prediabetic State; Pulse Wave Analysis; Vascular Stiffness

2023
Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy: a randomized controlled trial.
    BMC nephrology, 2021, 06-26, Volume: 22, Issue:1

    Topics: Albuminuria; Biomarkers; Blood Urea Nitrogen; Carnosine; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dietary Supplements; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Transforming Growth Factor beta

2021
Does supplementation with carnosine improve cardiometabolic health and cognitive function in patients with pre-diabetes and type 2 diabetes? study protocol for a randomised, double-blind, placebo-controlled trial.
    BMJ open, 2017, Sep-01, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Aged; Blood Glucose; Cardiovascular Diseases; Carnosine; Cognition; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Prediabetic State; Research Design; Young Adult

2017
l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.
    Nutrition research (New York, N.Y.), 2018, Volume: 49

    Topics: Adipose Tissue; Adult; Arginine; Blood Glucose; Body Composition; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Fasting; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Triglycerides; Tumor Necrosis Factor-alpha

2018
Effects of α-Lipoic Acid, Carnosine, and Thiamine Supplementation in Obese Patients with Type 2 Diabetes Mellitus: A Randomized, Double-Blind Study.
    Journal of medicinal food, 2018, Volume: 21, Issue:12

    Topics: Administration, Oral; Blood Glucose; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Obesity, Morbid; Surveys and Questionnaires; Thiamine; Thioctic Acid; Treatment Outcome

2018
Use of a urea, arginine and carnosine cream versus a standard emollient glycerol cream for treatment of severe xerosis of the feet in patients with type 2 diabetes: a randomized, 8 month, assessor-blinded, controlled trial.
    Current medical research and opinion, 2015, Volume: 31, Issue:6

    Topics: Administration, Cutaneous; Aged; Arginine; Carnosine; Diabetes Mellitus, Type 2; Emollients; Female; Glycerol; Humans; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Skin Diseases; Urea

2015
A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Adult; Aged; Blood Glucose; Body Composition; Carnosine; Chromium; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Fasting; Female; Humans; Male; Middle Aged; Muscles; Obesity; Overweight; Placebos; Plant Extracts; Prediabetic State

2015
Effects of carnosine supplementation on glucose metabolism: Pilot clinical trial.
    Obesity (Silver Spring, Md.), 2016, Volume: 24, Issue:5

    Topics: Adult; Blood Glucose; Body Weight; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Fasting; Female; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Overweight; Pilot Projects; Placebos; Risk Factors

2016
A Clinical Trial about a Food Supplement Containing α-Lipoic Acid on Oxidative Stress Markers in Type 2 Diabetic Patients.
    International journal of molecular sciences, 2016, Oct-28, Volume: 17, Issue:11

    Topics: Adult; Biomarkers; Blood Glucose; Body Mass Index; Body Weight; C-Reactive Protein; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Glutathione Peroxidase; Glycated Hemoglobin; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Oxidative Stress; Thioctic Acid; Zinc

2016
An urea, arginine and carnosine based cream (Ureadin Rx Db ISDIN) shows greater efficacy in the treatment of severe xerosis of the feet in Type 2 diabetic patients in comparison with glycerol-based emollient cream. A randomized, assessor-blinded, controll
    BMC dermatology, 2012, Sep-25, Volume: 12

    Topics: Administration, Topical; Adult; Aged; Arginine; Carnosine; Diabetes Mellitus, Type 2; Diabetic Foot; Drug Combinations; Emollients; Female; Foot Dermatoses; Glycerol; Humans; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Skin Cream; Treatment Outcome; Urea

2012
A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:4

    Topics: Adult; Aged; Alleles; Carnosine; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Europe; Female; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Humans; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Trinucleotide Repeats; United States; White People

2007

Other Studies

16 other study(ies) available for carnosine and Diabetes Mellitus, Type 2

ArticleYear
The Cost-Effectiveness of Supplemental Carnosine in Type 2 Diabetes.
    Nutrients, 2022, Jan-04, Volume: 14, Issue:1

    Topics: Australia; Carnosine; Cost-Benefit Analysis; Costs and Cost Analysis; Diabetes Mellitus, Type 2; Dietary Supplements; Glycemic Control; Health Care Costs; Humans

2022
Absence of endogenous carnosine synthesis does not increase protein carbonylation and advanced lipoxidation end products in brain, kidney or muscle.
    Amino acids, 2022, Volume: 54, Issue:7

    Topics: Animals; Antioxidants; Brain; Carnosine; Diabetes Mellitus, Type 2; Kidney; Mice; Muscles; Protein Carbonylation

2022
Carnosine Improves Cognitive Impairment Through Promoting SIRT6 Expression and Inhibiting Endoplasmic Reticulum Stress in a Diabetic Encephalopathy Model.
    Rejuvenation research, 2022, Volume: 25, Issue:2

    Topics: Animals; Apoptosis; Brain Diseases; Carnosine; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Endoribonucleases; Mice; Protein Serine-Threonine Kinases; Sirtuins

2022
Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells.
    Amino acids, 2023, Volume: 55, Issue:3

    Topics: beta-Alanine; Carnosine; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Resistance; Magnesium Oxide; Muscle Fibers, Skeletal; Muscle, Skeletal; Pyruvaldehyde

2023
Carnosine-Based Reversal of Diabetes-Associated Cognitive Decline via Activation of the Akt/mTOR Pathway and Modulation of Autophagy in a Rat Model of Type 2 Diabetes Mellitus.
    Dementia and geriatric cognitive disorders, 2023, Volume: 52, Issue:3

    Topics: Animals; Autophagy; Blood Glucose; Body Weight; Carnosine; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; TOR Serine-Threonine Kinases

2023
The effect of carnosine or β-alanine supplementation on markers of glycaemic control and insulin resistance in human and animal studies: a protocol for a systematic review and meta-analysis.
    Systematic reviews, 2020, 12-05, Volume: 9, Issue:1

    Topics: Bayes Theorem; beta-Alanine; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Glycemic Control; Humans; Insulin Resistance; Meta-Analysis as Topic; Systematic Reviews as Topic

2020
Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice.
    Amino acids, 2021, Volume: 53, Issue:8

    Topics: Administration, Oral; Animals; Anserine; Blood Glucose; Carnosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Limit of Detection; Mice; Obesity

2021
Carnosine protects stimulus-secretion coupling through prevention of protein carbonyl adduction events in cells under metabolic stress.
    Free radical biology & medicine, 2021, 11-01, Volume: 175

    Topics: Animals; Carnosine; Diabetes Complications; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Mice; Oxidative Stress; Protein Carbonylation

2021
Carnosine decreased oxidation and glycation products in serum and liver of high-fat diet and low-dose streptozotocin-induced diabetic rats.
    International journal of experimental pathology, 2017, Volume: 98, Issue:5

    Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Carnosine; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Evaluation, Preclinical; Glycated Hemoglobin; Glycation End Products, Advanced; Liver; Male; Organ Size; Oxidation-Reduction; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Streptozocin; Triglycerides

2017
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications.
    Cellular and molecular life sciences : CMLS, 2019, Volume: 76, Issue:22

    Topics: Amino Acids; Animals; Carnosine; Diabetes Complications; Diabetes Mellitus, Type 2; Dipeptidases; Gene Knockout Techniques; Kidney; Weight Gain; Zebrafish

2019
Carnosine decreases IGFBP1 production in db/db mice through suppression of HIF-1.
    The Journal of endocrinology, 2015, Volume: 225, Issue:3

    Topics: Animals; Antioxidants; Biomarkers; Carnosine; Cell Hypoxia; Diabetes Mellitus, Type 2; Dietary Supplements; Down-Regulation; Genes, Reporter; Hep G2 Cells; Heterozygote; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 1; Liver; Male; Mice, Mutant Strains; Obesity; Response Elements

2015
Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.
    Scientific reports, 2017, 03-10, Volume: 7

    Topics: Administration, Oral; Albuminuria; Animals; Blood Glucose; C-Peptide; Carnosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Gene Expression; Glomerular Mesangium; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Kidney Glomerulus; Male; Mice; Mice, Obese; Organ Size

2017
Reduced muscle carnosine content in type 2, but not in type 1 diabetic patients.
    Amino acids, 2012, Volume: 43, Issue:1

    Topics: Adult; Carnosine; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle, Skeletal; Oxidative Stress; Prospective Studies

2012
Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes.
    Amino acids, 2012, Volume: 43, Issue:1

    Topics: Animals; Carnosine; Cell Line; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Random Allocation; Skin; Wound Healing

2012
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.
    Diabetes, 2005, Volume: 54, Issue:8

    Topics: Aged; Carnosine; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Female; Gene Expression; Genetic Predisposition to Disease; Glucose; Humans; Kidney; Leucine; Male; Middle Aged; Repetitive Sequences, Amino Acid; RNA, Messenger; Sequence Alignment

2005
L-carnosine, a substrate of carnosinase-1, influences glucose metabolism.
    Diabetes, 2007, Volume: 56, Issue:10

    Topics: Animals; Blood Glucose; Carnosine; Cloning, Molecular; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidases; Disease Models, Animal; Genetic Predisposition to Disease; Genetic Variation; Glycated Hemoglobin; Humans; Mice; Mice, Inbred Strains; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Transfection

2007