carnosine has been researched along with Cataract in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 16 (40.00) | 29.6817 |
| 2010's | 18 (45.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, X; Liu, W; Wang, L | 1 |
| Hu, H; Peng, T; Wang, Y; Xia, R | 1 |
| Babizhayev, MA; Yegorov, YE | 3 |
| Huang, KF; Kuo, PT; Liao, JH; Lin, IL; Wu, SH; Wu, TH | 1 |
| Avetisov, SÉ; Muranov, KO; Ostrovskiĭ, MA; Polianskiĭ, NB; Polunin, GS; Sheremet, NL | 1 |
| Abdelkader, H; Alany, RG; Pierscionek, BK; Swinden, J | 1 |
| Hosseinkhani, S; Javadi, S; Tamaddon, AM; Uversky, VN; Yousefi, R | 1 |
| Abdelkader, H; Alany, RG; Longman, M; Pierscionek, B | 1 |
| Bastawrous, A; Dubois, VD | 1 |
| Babizhayev, MA | 9 |
| Babizhayev, MA; Guiotto, A; Kasus-Jacobi, A | 1 |
| Ding, Z; Guo, Y; Ha, W; Harding, JJ; Yan, H; Zhang, J | 1 |
| Akiyama, N; Natori, S; Nishigori, H; Sogo, S; Tsujimoto, M; Umeda, IO | 1 |
| Babizhayev, MA; Kasus-Jacobi, A | 1 |
| Attanasio, F; Cataldo, S; Fisichella, S; Nicoletti, S; Nicoletti, VG; Pignataro, B; Rizzarelli, E; Savarino, A | 1 |
| Babizhayev, MA; Burke, L; Micans, P; Richer, SP | 1 |
| Harding, JJ; Li, MY; Shi, Q; Yan, H | 1 |
| Liu, HW; Liu, YF; Peng, SL | 1 |
| Babizhayev, MA; Kasus-Jacobi, A; Khoroshilova-Maslova, IP | 1 |
| Calhoun, J; Cebulla, CM; Cloud, A; Tandon, A | 1 |
| Boldyrev, AA; Dizhevskaya, AK; Muranov, KO; Ostrovsky, MA | 1 |
| Babizhayev, MA; Bours, J; Brikman, IV; Deyev, AI; Yermakova, VN | 1 |
| Guo, Y; Yan, H | 1 |
| Boldyrev, AA; Formazuyk, VE; Quinn, PJ | 1 |
| Babizhayev, MA; Davydova, NG; Deyev, AI; Goldman, IM; Kurysheva, NI; Semiletov, YA; Yermakova, VN; Zhukotskii, AV | 1 |
| Babizhayev, MA; Davydova, NG; Deyev, AI; Doroshenko, VS; Goldman, IM; Semiletov, YA; Yermakova, VN; Zhukotskii, AV | 1 |
| Formaziuk, VE; Sergienko, VI | 1 |
| Dudina, EI; Formaziuk, VE; Sergienko, VI | 1 |
| Boldyrev, AA; Chasovnikova, LV; Formazyuk, VE; Sergienko, VI; Severin, SE | 1 |
| Babizhaev, MA; Boldyrev, AA; Dupin, AM; Severin, SE | 1 |
13 review(s) available for carnosine and Cataract
| Article | Year |
|---|---|
Biomarkers of oxidative stress and cataract. Novel drug delivery therapeutic strategies targeting telomere reduction and the expression of telomerase activity in the lens epithelial cells with N-acetylcarnosine lubricant eye drops: anti-cataract which hel
Topics: Administration, Ophthalmic; Animals; Antioxidants; Biomarkers; Carnosine; Cataract; Cell Membrane; Cellular Senescence; Ceruloplasmin; Chemistry, Pharmaceutical; Dogs; Drug Carriers; Epithelial Cells; Lens, Crystalline; Ophthalmic Solutions; Oxidative Stress; Prodrugs; Technology, Pharmaceutical; Telomerase; Telomere | 2014 |
Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-
Topics: Administration, Ophthalmic; Age Factors; Aging; Animals; Antioxidants; Carnosine; Cataract; Cornea; Drug Compounding; Drug Delivery Systems; Epithelial Cells; Humans; Lens, Crystalline; Ocular Absorption; Ophthalmic Solutions; Oxidative Stress; Solubility; Telomere Homeostasis | 2016 |
N-acetylcarnosine (NAC) drops for age-related cataract.
Topics: Aged; Aged, 80 and over; Aging; Carnosine; Cataract; Disease Progression; Humans; Middle Aged; Ophthalmic Solutions; Randomized Controlled Trials as Topic | 2017 |
Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine therapy.
Topics: Aged; Animals; Carnosine; Cataract; Disease Models, Animal; Humans; Lens, Crystalline; Telomere; Vision, Ocular; Visual Acuity | 2010 |
Designation of imidazole-containing dipeptides as pharmacological chaperones.
Topics: Carnosine; Cataract; Drug Carriers; Humans; Imidazoles; Lipid Peroxidation; Macular Degeneration; Molecular Chaperones; Oxidative Stress | 2011 |
Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care.
Topics: Administration, Ophthalmic; Animals; Carnosine; Cataract; Chromatography, High Pressure Liquid; Clinical Trials, Phase II as Topic; Drug Delivery Systems; Eye Diseases; Humans; Prodrugs; Randomized Controlled Trials as Topic; Vitreoretinopathy, Proliferative | 2012 |
Biomarkers and special features of oxidative stress in the anterior segment of the eye linked to lens cataract and the trabecular meshwork injury in primary open-angle glaucoma: challenges of dual combination therapy with N-acetylcarnosine lubricant eye d
Topics: Administration, Ophthalmic; Administration, Oral; Animals; Biomarkers; Blindness; Carnosine; Cataract; Glaucoma, Open-Angle; Humans; Ophthalmic Solutions; Oxidative Stress; Trabecular Meshwork | 2012 |
Structural and functional properties, chaperone activity and posttranslational modifications of alpha-crystallin and its related subunits in the crystalline lens: N-acetylcarnosine, carnosine and carcinine act as alpha- crystallin/small heat shock protein
Topics: Age Factors; alpha-Crystallins; Animals; Carnosine; Cataract; Drug Design; Humans; Lens, Crystalline; Molecular Chaperones; Oxidative Stress; Patents as Topic | 2012 |
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes.
Topics: Aging; Animals; Carnosine; Cataract; Dog Diseases; Dogs; Humans; Lipid Peroxidation; Randomized Controlled Trials as Topic | 2004 |
[Preventive effect of carnosine on cataract development].
Topics: Animals; Carnosine; Cataract; Humans | 2006 |
Carnosine: its properties, functions and potential therapeutic applications.
Topics: Animals; Anserine; Antihypertensive Agents; Antineoplastic Agents; Antioxidants; Carnosine; Cataract; Dipeptidases; Dipeptides; Dogs; Free Radical Scavengers; Histidine; Humans; Membrane Lipids; Neurotransmitter Agents; Wound Healing | 1992 |
[The use of carnosine in medical practice. Priorities: past and future].
Topics: Anions; Carnosine; Cataract; Humans; Hypochlorous Acid; Neutrophils | 1992 |
The antioxidative properties of carnosine, a natural histidine containing dipeptide.
Topics: Animals; Antioxidants; Carnosine; Cataract; Dipeptides; Glutathione; Humans; Lens, Crystalline | 1987 |
6 trial(s) available for carnosine and Cataract
| Article | Year |
|---|---|
N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications.
Topics: Aged; Aged, 80 and over; Aldehydes; Aminooxyacetic Acid; Animals; Biological Availability; Carnosine; Cataract; Cornea; Cross-Over Studies; Diabetes Complications; Disease Models, Animal; Drug Administration Schedule; Drug Delivery Systems; Drug Synergism; Female; Glycosylation; Histidine; Humans; Hydrazines; Lubricants; Male; Middle Aged; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Ophthalmoscopy; Rabbits | 2009 |
State of the art clinical efficacy and safety evaluation of N-acetylcarnosine dipeptide ophthalmic prodrug. Principles for the delivery, self-bioactivation, molecular targets and interaction with a highly evolved histidyl-hydrazide structure in the treatm
Topics: Administration, Topical; Aged; Aged, 80 and over; Antioxidants; Carnosine; Cataract; Contact Lenses; Double-Blind Method; Drug Delivery Systems; Female; Glycation End Products, Advanced; Glycosylation; Histidine; Humans; Hydrazines; Lipid Peroxidation; Liposomes; Lubricants; Male; Middle Aged; Ophthalmic Solutions; Oxidative Stress; Prodrugs; Visual Acuity | 2009 |
N-Acetylcarnosine sustained drug delivery eye drops to control the signs of ageless vision: glare sensitivity, cataract amelioration and quality of vision currently available treatment for the challenging 50,000-patient population.
Topics: Aged; Aged, 80 and over; Carnosine; Cataract; Delayed-Action Preparations; Female; Glare; Humans; Macular Degeneration; Male; Middle Aged; Ophthalmic Solutions; Vision, Ocular | 2009 |
Rejuvenation of visual functions in older adult drivers and drivers with cataract during a short-term administration of N-acetylcarnosine lubricant eye drops.
Topics: Aged; Automobile Driving; Carnosine; Cataract; Double-Blind Method; Female; Glare; Humans; Male; Middle Aged; Ophthalmic Solutions; Vision Disorders; Visual Acuity | 2004 |
N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts.
Topics: Age Factors; Aged; Carnosine; Cataract; Eye; Female; Humans; Lens, Crystalline; Male; Middle Aged; Observer Variation; Oxidative Stress; Sex Factors; Time Factors | 2001 |
Efficacy of N-acetylcarnosine in the treatment of cataracts.
Topics: Aged; Aged, 80 and over; Carnosine; Cataract; Female; Humans; Male; Middle Aged | 2002 |
21 other study(ies) available for carnosine and Cataract
| Article | Year |
|---|---|
An approach to revolutionize cataract treatment by enhancing drug probing through intraocular cell line.
Topics: Administration, Ophthalmic; Animals; Carnosine; Cataract; Cell Culture Techniques; Cell Line; Cornea; Delayed-Action Preparations; Drug Delivery Systems; Endothelial Cells; Goats; Humans; Nanoparticles; Ocular Absorption; Particle Size | 2018 |
Biosynthesis, characterization and cytotoxicity of gold nanoparticles and their loading with N-acetylcarnosine for cataract treatment.
Topics: Animals; Biocompatible Materials; Carnosine; Cataract; Cell Line; Cell Survival; Cucurbitaceae; Gold; Green Chemistry Technology; Metal Nanoparticles; Mice; Particle Size; Plant Bark; Plant Extracts; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2018 |
Carnosine ameliorates lens protein turbidity formations by inhibiting calpain proteolysis and ultraviolet C-induced degradation.
Topics: Amino Acid Sequence; Animals; Calpain; Carnosine; Cataract; Crystallins; Glycoproteins; Humans; Lens, Crystalline; Molecular Sequence Data; Proteolysis; Sequence Alignment; Swine; Ultraviolet Rays | 2014 |
[Deceleration of cataract development in rats under the action of N-acetylcarnosine and D-pantethine mixture].
Topics: Animals; Carnosine; Cataract; Chromatography, Gel; Drug Combinations; Eye Proteins; Injections, Intraperitoneal; Lens, Crystalline; Male; Ophthalmic Solutions; Pantetheine; Protective Agents; Protein Aggregates; Radiation Injuries, Experimental; Rats; Rats, Wistar; Solubility; Ultraviolet Rays | 2014 |
Analytical and physicochemical characterisation of the senile cataract drug dipeptide β-alanyl-L-histidine (carnosine).
Topics: Acetonitriles; Carnosine; Cataract; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lens, Crystalline; Linear Models; Octanols; Oxygen; Phospholipids; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Temperature | 2015 |
Protective effects of carnosine on dehydroascorbate-induced structural alteration and opacity of lens crystallins: important implications of carnosine pleiotropic functions to combat cataractogenesis.
Topics: alpha-Crystallins; Animals; Aspirin; Carnosine; Cataract; Cattle; Dehydroascorbic Acid; Electrophoretic Mobility Shift Assay; gamma-Crystallins; Glycosylation; Lens, Crystalline; Protective Agents; Tissue Culture Techniques | 2017 |
On the Anticataractogenic Effects of L-Carnosine: Is It Best Described as an Antioxidant, Metal-Chelating Agent or Glycation Inhibitor?
Topics: Antioxidants; Carnosine; Cataract; Chelating Agents; Humans; Lens, Crystalline | 2016 |
Ocular drug metabolism of the bioactivating antioxidant N-acetylcarnosine for vision in ophthalmic prodrug and codrug design and delivery.
Topics: Animals; Antioxidants; Carnosine; Cataract; Chromatography, High Pressure Liquid; Cornea; Drug Design; Eye; Humans; Lens, Crystalline; Lipid Peroxidation; Liposomes; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Prodrugs; Rabbits | 2008 |
Effect of carnosine, aminoguanidine, and aspirin drops on the prevention of cataracts in diabetic rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; Carnosine; Cataract; Cornea; Diabetes Mellitus, Experimental; Disease Progression; Eye Proteins; Glycosylation; Guanidines; Lens, Crystalline; Male; Ophthalmic Solutions; Rats; Rats, Sprague-Dawley; Staining and Labeling; Streptozocin | 2008 |
5-S-GAD, a novel radical scavenging compound, prevents lens opacity development.
Topics: alpha-Crystallins; Animals; Biphenyl Compounds; Carnosine; Cataract; Cells, Cultured; Chick Embryo; Cyclic N-Oxides; Diamide; Dihydroxyphenylalanine; Disease Progression; Dose-Response Relationship, Drug; Free Radical Scavengers; Galactose; Glucocorticoids; Glutathione; Insecta; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Picrates; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides | 2009 |
Protective effects of L- and D-carnosine on alpha-crystallin amyloid fibril formation: implications for cataract disease.
Topics: alpha-Crystallins; Amyloid; Animals; Calorimetry, Differential Scanning; Carnosine; Cataract; Cattle; Circular Dichroism; Female; Microscopy, Atomic Force; Molecular Chaperones; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism | 2009 |
Effect of a combination of carnosine and aspirin eye drops on streptozotocin -- induced diabetic cataract in rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; Carnosine; Cataract; Diabetes Complications; Drinking Behavior; Drug Therapy, Combination; Feeding Behavior; Glycosuria; Lens, Crystalline; Male; Ophthalmic Solutions; Rats; Rats, Sprague-Dawley; Solubility; Streptozocin; Sulfhydryl Compounds; Time Factors | 2009 |
[Effects of L-carnosine in preventing and treating rat cataract induced by sodium selenite].
Topics: Animals; Carnosine; Cataract; Lens, Crystalline; Rats; Rats, Wistar; Sodium Selenite | 2009 |
Potentiation of intraocular absorption and drug metabolism of N-acetylcarnosine lubricant eye drops: drug interaction with sight threatening lipid peroxides in the treatment for age-related eye diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antioxidants; Aqueous Humor; Carnosine; Cataract; Delayed-Action Preparations; Drug Synergism; Eye; Female; Humans; Lens, Crystalline; Lipid Peroxidation; Lipid Peroxides; Liposomes; Male; Microscopy, Electron; Middle Aged; Ophthalmic Solutions; Rabbits; Tissue Culture Techniques; Young Adult | 2009 |
Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for cataract
Topics: Aged; Aging; Animals; Antioxidants; Aqueous Humor; Carnosine; Cataract; Female; Humans; Hydrogen Peroxide; Lens, Crystalline; Lipid Peroxidation; Lipid Peroxides; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mitochondria; Ophthalmic Solutions; Oxidation-Reduction; Oxidative Stress; Phospholipids; Prodrugs; Rabbits; Reactive Oxygen Species | 2011 |
Rapid formation and resolution of cataracts following orthopedic surgery for a patient with Charcot-Marie-Tooth disease.
Topics: Carnosine; Cataract; Charcot-Marie-Tooth Disease; Foot Deformities, Acquired; Humans; Male; Middle Aged; Orthopedic Procedures; Remission, Spontaneous; Self Medication | 2012 |
Natural dipeptides as mini-chaperones: molecular mechanism of inhibition of lens βL-crystallin aggregation.
Topics: Animals; Anserine; beta-Crystallins; Carnosine; Cataract; Cattle; Dipeptides; Hydrophobic and Hydrophilic Interactions; Kinetics; Lens, Crystalline; Molecular Chaperones; Protein Carbonylation; Protein Conformation; Ultraviolet Rays | 2012 |
Analysis of lipid peroxidation and electron microscopic survey of maturation stages during human cataractogenesis: pharmacokinetic assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for cataract prevention.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Aqueous Humor; Biological Availability; Carnosine; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Lens, Crystalline; Lipid Peroxidation; Liposomes; Lubrication; Male; Microscopy, Electron; Middle Aged; Ophthalmic Solutions; Prodrugs; Rabbits | 2005 |
[Formation of stable chloramine complex in interactions of carnosine and hypochlorite anion].
Topics: Animals; Carnosine; Cataract; Cattle; Chloramines; Drug Interactions; Humans; Sodium Hypochlorite | 1992 |
The antioxidative properties of carnosine and other drugs.
Topics: Acridines; alpha-Tocopherol; Animals; Aspirin; Carnosine; Cataract; Dipeptides; Ferrous Compounds; Kinetics; Lipid Peroxidation; Oxazines; Oxidation-Reduction; Rats; Thiobarbiturates; Tocopherols; Vitamin E | 1990 |
Antioxidant activity of L-carnosine, a natural histidine-containing dipeptide in crystalline lens.
Topics: Animals; Antioxidants; Carnosine; Cataract; Dipeptides; Histidine; In Vitro Techniques; Lens, Crystalline; Lipid Peroxidation; Rabbits | 1989 |