Page last updated: 2024-08-21

carnosine and Aging

carnosine has been researched along with Aging in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19906 (8.57)18.7374
1990's6 (8.57)18.2507
2000's21 (30.00)29.6817
2010's31 (44.29)24.3611
2020's6 (8.57)2.80

Authors

AuthorsStudies
Kisi, S; Yamaguchi, M1
Ozaki, K; Yamaguchi, M1
Hoshino, T; Katakura, A; Kato, Y; Sugahara, K1
Ardianto, C; Durairaj, M; Ganesan, RM; Goh, KW; Mahalingam, VT; Ming, LC; Srinivasan, K; Sureshkumar, K; Undela, K1
Cai, WW; Dai, Z; Deng, YX; Li, BY; Liu, HF; Liu, XQ; Lu, XY; Song, L; Wang, Q; Xu, TT; Zhang, SJ; Zhu, WL1
Bastian, A; Bruegmann, T; Eckhardt, M; Sasse, P; Wang-Eckhardt, L1
Banerjee, S; Dunbar, GL; Mukherjee, B; Poddar, MK1
Aydin, F; Coban, J; Dogru-Abbasoglu, S; Kalaz, EB; Kucukgergin, C; Uysal, M1
Aydın, AF; Bingül, İ; Çoban, J; Doğru-Abbasoğlu, S; Uysal, M; Yılmaz, Z1
Artioli, GG; Jones, RL; Sale, C1
Aldini, G; Altomare, A; Baron, G; Carini, M; Gilardoni, E; Regazzoni, L1
Banerjee, S; Poddar, MK3
Bingül, I; Çoban, J; Dogru-Abbasoglu, S; Oztezcan, S; Uysal, M; Yesil-Mizrak, K1
Micans, P1
Hipkiss, AR8
Babizhayev, MA; Vishnyakova, KS; Yegorov, YE1
Babizhayev, MA; Kasus-Jacobi, A; Vishnyakova, KS; Yegorov, YE1
Babizhayev, MA; Yegorov, YE3
Aydın, AF; Çoban, J; Doğan-Ekici, I; Doğru-Abbasoğlu, S; Koçak-Toker, N; Uysal, M1
Chalisova, NI; Khavinson, VKh; Lin'kova, NS; Orlova, AO; Ryzhak, GA; Zhekalov, AN1
Banerjee, S; Ghosh, TK; Poddar, MK1
Acosta, S; Bickford, PC; Flowers, A; Hudson, C; Lee, JY; Sanberg, CD; Small, B1
Bogo, MR; Cararo, JH; Ferreira, GC; Gonçalves, CL; Guerra Martinez, C; Hipkiss, AR; Kist, LW; Kurtenbach, E; Macedo, LW; Maravai, SG; Oliveira, GM; Schuck, PF; Streck, EL1
Aydın, AF; Betül-Kalaz, E; Çoban, J; Doğan-Ekici, I; Doğru-Abbasoğlu, S; Uysal, M1
Cao, Y; Hisatsune, T; Imabayashi, E; Kaneko, J; Katakura, Y; Kurashige, H; Matsuda, H; Satsu, H; Totsuka, M1
Baye, E; de Courten, B; Hipkiss, AR1
Bastawrous, A; Dubois, VD1
Derave, W; Harris, RC; Hespel, P; Jones, G1
Malavolta, M; Mocchegiani, E1
Aydin, AF; Koçak-Toker, N; Küçükgergin, C; Ozdemirler-Erata, G; Uysal, M1
Acosta, S; Bickford, PC; Gemma, C; Jernberg, J; Sanberg, CD; Sanberg, PR; Small, BJ1
Babizhayev, MA1
Canzoniero, LM; Ciavardelli, D; Corona, C; Frazzini, V; La Sorda, R; Lattanzio, R; Piantelli, M; Rizzarelli, E; Sensi, SL; Silvestri, E1
Artioli, GG; Benatti, FB; de Sá-Pinto, AL; del Favero, S; Gualano, B; Harris, RC; Hayashi, AP; Lancha-Junior, AH; Leite, CC; Otaduy, MC; Pereira, RM; Roschel, H; Solis, MY; Wise, JA1
Bracale, R; Davinelli, S; Di Marco, R; Quattrone, A; Scapagnini, G; Zella, D1
Gopko, AV; Kulibin, AY; Makarov, AA; Mikhaleva, YY; Semenova, ML; Zakhidov, ST1
Bershtein, LM; Gamayunova, VB; Kovalenko, IG; Poroshina, TE; Rozanov, YM; Tsyrlina, EV; Vasil'ev, DA1
Bershteĭn, LM; Kovalenko, IG; Poroshina, TE; Tsyrlina, EV; Vasil'ev, DA1
Babizhayev, MA; Bours, J; Brikman, IV; Deyev, AI; Yermakova, VN1
Li, QH; Shao, L; Tan, Z1
Garrett, MR; Perry, G; Reddy, VP; Smith, MA1
Gopko, AV; Kulibin, AY; Semenova, ML; Zakhidov, ST1
Harris, RC; Maffulli, N; Tallon, MJ; Tarnopolsky, MA1
Chan, PW; George, RP; Kucera, CM; Lenney, JF; Rinzler, GS; Weiss, AM1
Bell, AW; Carnegie, PR; Hee, KP1
Takahashi, H1
Coopersmith, R; Leon, M1
Boldyrev, AA; Gallant, SC; Sukhich, GT1
Brownson, C; Hipkiss, AR2
Stuerenburg, HJ1
Gallant, S; Semyonova, M; Yuneva, M1
Ma, C; Shen, F; Wang, AM; Xie, ZH1
De Marchis, S; Fasolo, A; Giffard, C; Modena, C; Peretto, P1
Brownson, C; Carrier, MJ; Hipkiss, AR1
Barbaro, D; Fisher, DE; Fisher, H; Strumeyer, DH1
Bondarenko, TI; Makletsova, MG; Uskova, NI1
Gash, SP; Harris, RC; Marlin, DJ; Snow, DH1
Nagai, K; Suda, T1

Reviews

22 review(s) available for carnosine and Aging

ArticleYear
Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis.
    Frontiers in bioscience (Landmark edition), 2023, 01-18, Volume: 28, Issue:1

    Topics: Aging; Cardiovascular Diseases; Carnosine; Humans

2023
Carnosine in health and disease.
    European journal of sport science, 2019, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Aging; Brain; Carnosine; Cognition; Diabetes Mellitus, Type 2; Heart; Humans; Kidney; Muscle, Skeletal; Neoplasms; Neurodegenerative Diseases; Pancreas; Performance-Enhancing Substances

2019
The Disposal of Reactive Carbonyl Species through Carnosine Conjugation: What We Know Now.
    Current medicinal chemistry, 2020, Volume: 27, Issue:11

    Topics: Aging; Carnosine; Humans; Obesity; Oxidation-Reduction; Proteins

2020
Aging risk factors and Parkinson's disease: contrasting roles of common dietary constituents.
    Neurobiology of aging, 2014, Volume: 35, Issue:6

    Topics: Aging; Animals; Carnosine; Clinical Trials as Topic; Dietary Carbohydrates; Dietary Supplements; Double-Blind Method; Humans; Parkinson Disease; Pyruvaldehyde; Risk Factors; Treatment Outcome

2014
Oxidative damage impact on aging and age-related diseases: drug targeting of telomere attrition and dynamic telomerase activity flirting with imidazole-containing dipeptides.
    Recent patents on drug delivery & formulation, 2014, Volume: 8, Issue:3

    Topics: Aging; Animals; Carnosine; Dipeptides; Drug Delivery Systems; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Oxidative Stress; Telomerase; Telomere; Telomere Homeostasis

2014
Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing d
    Recent patents on endocrine, metabolic & immune drug discovery, 2014, Volume: 8, Issue:3

    Topics: Aging; Carnosine; Dipeptides; Humans; Imidazoles; Life Style; Molecular Targeted Therapy; Patents as Topic; Rejuvenation; Telomere Homeostasis; Telomere Shortening

2014
An "enigmatic" L-carnosine (β-alanyl-L-histidine)? Cell proliferative activity as a fundamental property of a natural dipeptide inherent to traditional antioxidant, anti-aging biological activities: balancing and a hormonally correct agent, novel patented
    Recent patents on drug delivery & formulation, 2015, Volume: 9, Issue:1

    Topics: Administration, Oral; Aging; Animals; Antioxidants; Brain; Carnosine; Cell Proliferation; Chemistry, Pharmaceutical; Dipeptides; Health Status; Humans; Hypothalamo-Hypophyseal System; Muscle, Skeletal; Pituitary-Adrenal System; Stress, Psychological

2015
Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-
    Recent patents on drug delivery & formulation, 2016, Volume: 10, Issue:2

    Topics: Administration, Ophthalmic; Age Factors; Aging; Animals; Antioxidants; Carnosine; Cataract; Cornea; Drug Compounding; Drug Delivery Systems; Epithelial Cells; Humans; Lens, Crystalline; Ocular Absorption; Ophthalmic Solutions; Oxidative Stress; Solubility; Telomere Homeostasis

2016
Carnosine and the processes of ageing.
    Maturitas, 2016, Volume: 93

    Topics: Aging; Animals; Carnosine; Dietary Supplements; Humans; Inflammation; Oxidative Stress; Signal Transduction

2016
N-acetylcarnosine (NAC) drops for age-related cataract.
    The Cochrane database of systematic reviews, 2017, 02-28, Volume: 2

    Topics: Aged; Aged, 80 and over; Aging; Carnosine; Cataract; Disease Progression; Humans; Middle Aged; Ophthalmic Solutions; Randomized Controlled Trials as Topic

2017
Possible new antiaging strategies related to neuroendocrine-immune interactions.
    Neuroimmunomodulation, 2008, Volume: 15, Issue:4-6

    Topics: Adult; Aged; Aging; Animals; Anticarcinogenic Agents; Antioxidants; Carnosine; Child, Preschool; Dogs; Female; Ghrelin; Humans; Leptin; Longevity; Male; Neuroimmunomodulation; Nitric Oxide Donors; Selegiline; Young Adult; Zinc

2008
Carnosine and its possible roles in nutrition and health.
    Advances in food and nutrition research, 2009, Volume: 57

    Topics: Aging; Animals; Carnosine; Diet; Dietary Supplements; Free Radical Scavengers; Health Status; Humans; Nutritional Status

2009
Therapeutic uses of drug-carrier systems for imidazole-containing dipeptide compounds that act as pharmacological chaperones and have significant impact on the treatment of chronic diseases associated with increased oxidative stress and the formation of a
    Critical reviews in therapeutic drug carrier systems, 2010, Volume: 27, Issue:2

    Topics: Aging; Animals; Biomarkers; Carnosine; Chemistry, Pharmaceutical; Chronic Disease; Drug Carriers; Drug Compounding; Drug Design; Eye Diseases; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lipid Peroxidation; Models, Molecular; Molecular Structure; Oxidative Stress; Skin; Skin Aging; Skin Diseases; Structure-Activity Relationship

2010
Energy metabolism, proteotoxic stress and age-related dysfunction - protection by carnosine.
    Molecular aspects of medicine, 2011, Volume: 32, Issue:4-6

    Topics: Aging; Animals; Carnosine; Energy Metabolism; Glycation End Products, Advanced; Glycolysis; Humans; Pyruvaldehyde

2011
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes.
    Drugs in R&D, 2004, Volume: 5, Issue:3

    Topics: Aging; Animals; Carnosine; Cataract; Dog Diseases; Dogs; Humans; Lipid Peroxidation; Randomized Controlled Trials as Topic

2004
Carnosine: a versatile antioxidant and antiglycating agent.
    Science of aging knowledge environment : SAGE KE, 2005, May-04, Volume: 2005, Issue:18

    Topics: Aging; Alzheimer Disease; Antioxidants; Carnosine; DNA Damage; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Metals; Oxidative Stress; Transition Elements

2005
Glycation, ageing and carnosine: are carnivorous diets beneficial?
    Mechanisms of ageing and development, 2005, Volume: 126, Issue:10

    Topics: Aging; Animals; Carnosine; Diet, Vegetarian; Glycosylation; Humans; Neurons

2005
Would carnosine or a carnivorous diet help suppress aging and associated pathologies?
    Annals of the New York Academy of Sciences, 2006, Volume: 1067

    Topics: Aging; Animals; Carnosine; Diet, Vegetarian; Glycosylation; Humans; Neurons

2006
Carnosine, a protective, anti-ageing peptide?
    The international journal of biochemistry & cell biology, 1998, Volume: 30, Issue:8

    Topics: Aging; Animals; Carnosine; Humans; Molecular Structure

1998
A possible new role for the anti-ageing peptide carnosine.
    Cellular and molecular life sciences : CMLS, 2000, Volume: 57, Issue:5

    Topics: Aging; Animals; Carnosine; Cellular Senescence; Cross-Linking Reagents; Glycation End Products, Advanced; Glycosylation; Humans; Ovalbumin; Proteins

2000
The roles of carnosine in aging of skeletal muscle and in neuromuscular diseases.
    Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:7

    Topics: Aging; Antioxidants; Carnosine; Humans; Muscle, Skeletal; Neuromuscular Diseases; Oxidative Stress

2000
Use of carnosine as a natural anti-senescence drug for human beings.
    Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:7

    Topics: Aging; Carnosine; Free Radicals; Humans

2000

Trials

3 trial(s) available for carnosine and Aging

ArticleYear
Aortic wave velocity: a noninvasive method to measure the stiffness of arteries and the clinical results of supplements that appear to improve arterial stiffness.
    Current aging science, 2013, Volume: 6, Issue:1

    Topics: Adult; Aged; Aging; Arginine; Cardiovascular Diseases; Carnosine; Dietary Supplements; Female; Glycation End Products, Advanced; Guanidines; Humans; Male; Middle Aged; Pulse Wave Analysis; Resveratrol; Risk Factors; Stilbenes; Vascular Stiffness

2013
Effect of Anserine/Carnosine Supplementation on Verbal Episodic Memory in Elderly People.
    Journal of Alzheimer's disease : JAD, 2016, Volume: 50, Issue:1

    Topics: Adult; Aged; Aging; Anserine; Brain; Carnosine; Cytokines; Dietary Supplements; Double-Blind Method; Female; Gene Expression Regulation; Humans; Image Processing, Computer-Assisted; Male; Memory, Episodic; Middle Aged; Neuropsychological Tests; Oligonucleotide Array Sequence Analysis; Verbal Learning

2016
Beta-alanine (Carnosyn™) supplementation in elderly subjects (60-80 years): effects on muscle carnosine content and physical capacity.
    Amino acids, 2012, Volume: 43, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; beta-Alanine; Carnosine; Dietary Supplements; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Muscle, Skeletal; Physical Endurance

2012

Other Studies

45 other study(ies) available for carnosine and Aging

ArticleYear
Stimulatory effect of beta-alanyl-L-histidinato zinc on alkaline phosphatase activity in bone tissues from elderly rats: comparison with zinc sulfate action.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:2

    Topics: Aging; Alkaline Phosphatase; Animals; Carnosine; Culture Techniques; Dipeptides; Estradiol; Female; Femur; Insulin; Organometallic Compounds; Rats; Sodium Fluoride; Sulfates; Zinc; Zinc Compounds; Zinc Sulfate

1994
Effect of the new zinc compound beta-alanyl-L-histidinato zinc on bone metabolism in elderly rats.
    Pharmacology, 1990, Volume: 41, Issue:6

    Topics: Administration, Oral; Aging; Alkaline Phosphatase; Animals; Anti-Ulcer Agents; Bone and Bones; Calcification, Physiologic; Carnosine; Dipeptides; DNA; Dose-Response Relationship, Drug; Drug Administration Schedule; Femur; Male; Organometallic Compounds; Rats; Rats, Inbred Strains; Zinc Compounds

1990
Aging-related metabolic changes in the extensor digitorum longus muscle of senescence-accelerated mouse-prone 8.
    Geriatrics & gerontology international, 2022, Volume: 22, Issue:2

    Topics: Aging; Animals; Carnosine; Mice; Muscle, Skeletal; Sarcopenia

2022
Carnosine ameliorates age-related dementia via improving mitochondrial dysfunction in SAMP8 mice.
    Food & function, 2020, Mar-01, Volume: 11, Issue:3

    Topics: Aging; Animals; Apoptosis; Carnosine; Dementia; Hippocampus; Inflammation; Male; Memory; Mice; Mitochondrial Diseases; Neurons; Oxidative Stress

2020
Carnosine synthase deficiency is compatible with normal skeletal muscle and olfactory function but causes reduced olfactory sensitivity in aging mice.
    The Journal of biological chemistry, 2020, 12-11, Volume: 295, Issue:50

    Topics: Aging; Animals; Carnosine; Mice; Mice, Knockout; Muscle Contraction; Muscle, Skeletal; Peptide Synthases; Receptors, Odorant

2020
Carnosine improves aging-induced cognitive impairment and brain regional neurodegeneration in relation to the neuropathological alterations in the secondary structure of amyloid beta (Aβ).
    Journal of neurochemistry, 2021, Volume: 158, Issue:3

    Topics: Aging; Amyloid beta-Peptides; Animals; Brain; Carnosine; Cognitive Dysfunction; Male; Nerve Degeneration; Peptide Fragments; Protein Structure, Secondary; Rats; Rats, Wistar

2021
Carnosine Treatment Diminished Oxidative Stress and Glycation Products in Serum and Tissues of D-Galactose-Treated Rats.
    Current aging science, 2018, Volume: 11, Issue:1

    Topics: Advanced Oxidation Protein Products; Age Factors; Aging; Animals; Antioxidants; Biomarkers; Brain; Carnosine; Galactose; Glycation End Products, Advanced; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats, Wistar; Reactive Oxygen Species

2018
Antiglycation and anti-oxidant efficiency of carnosine in the plasma and liver of aged rats.
    Geriatrics & gerontology international, 2017, Volume: 17, Issue:12

    Topics: Aging; Animals; Antioxidants; Carnosine; Female; Glycation End Products, Advanced; Liver; Male; Oxidants; Oxidative Stress; Rats; Rats, Wistar

2017
Platelet monoamine oxidase-A activity and aging: effect of carnosine.
    The journal of physiological sciences : JPS, 2013, Volume: 63, Issue:4

    Topics: Aging; Animals; Blood Platelets; Carnosine; Kinetics; Male; Monoamine Oxidase; Rats; Rats, Wistar; Serotonin

2013
Effects of carnosine plus vitamin E and betaine treatments on oxidative stress in some tissues of aged rats.
    Current aging science, 2013, Volume: 6, Issue:2

    Topics: Aging; Animals; Antioxidants; Betaine; Body Weight; Brain; Carnosine; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Models, Animal; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Vitamin E

2013
Carnosine: effect on aging-induced increase in brain regional monoamine oxidase-A activity.
    Neuroscience research, 2015, Volume: 92

    Topics: Aging; Animals; Brain; Carnosine; Male; Mitochondria; Monoamine Oxidase; Rats; Rats, Wistar

2015
Carnosine and vitamin E--a promising pair in the combat against testicular oxidative stress in aged rats.
    Andrologia, 2015, Volume: 47, Issue:10

    Topics: Aging; Animals; Carnosine; Drug Interactions; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Testis; Vitamin E

2015
[Short peptides stimulate skin cell regeneration during ageing].
    Advances in gerontology = Uspekhi gerontologii, 2014, Volume: 27, Issue:4

    Topics: Aging; Animals; Carnosine; Cell Proliferation; Fibroblasts; In Vitro Techniques; Male; Oligopeptides; Rats, Wistar; Regeneration; Skin; Skin Aging

2014
Carnosine reverses the aging-induced down regulation of brain regional serotonergic system.
    Mechanisms of ageing and development, 2015, Volume: 152

    Topics: Aging; Animals; Brain; Carnosine; Down-Regulation; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Serotonin

2015
NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats.
    Journal of neuroinflammation, 2015, Sep-17, Volume: 12

    Topics: Aging; Animals; beta Catenin; Calcium-Binding Proteins; Carnosine; Cell Proliferation; Cholecalciferol; Computational Biology; Cytokines; Dentate Gyrus; Doublecortin Domain Proteins; Doublecortin Protein; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Microfilament Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuropeptides; NF-E2-Related Factor 2; Plant Extracts; Rats; Rats, Inbred F344; Wnt Signaling Pathway

2015
Acute Carnosine Administration Increases Respiratory Chain Complexes and Citric Acid Cycle Enzyme Activities in Cerebral Cortex of Young Rats.
    Molecular neurobiology, 2016, Volume: 53, Issue:8

    Topics: Aging; Animals; Carnosine; Cerebral Cortex; Citric Acid Cycle; Electron Transport; Male; Mitochondria; Oxidative Phosphorylation; Rats, Wistar; RNA, Messenger; Transcription Factors; Up-Regulation

2016
Carnosine and taurine treatments diminished brain oxidative stress and apoptosis in D-galactose aging model.
    Metabolic brain disease, 2016, Volume: 31, Issue:2

    Topics: Aging; Animals; Antioxidants; Apoptosis; Carnosine; Galactose; Glutathione Peroxidase; Histidine; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Superoxide Dismutase; Taurine

2016
Aging-induced changes in brain regional serotonin receptor binding: Effect of Carnosine.
    Neuroscience, 2016, Apr-05, Volume: 319

    Topics: Aging; Animals; Antioxidants; Brain; Carnosine; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin

2016
Creatine supplementation augments skeletal muscle carnosine content in senescence-accelerated mice (SAMP8).
    Rejuvenation research, 2008, Volume: 11, Issue:3

    Topics: Aging; Animals; Anserine; beta-Alanine; Carnosine; Creatinine; Dietary Supplements; Male; Mice; Muscle Fatigue; Muscle, Skeletal; Taurine

2008
On the enigma of carnosine's anti-ageing actions.
    Experimental gerontology, 2009, Volume: 44, Issue:4

    Topics: Aging; Animals; Carnosine; Cellular Senescence; Humans; Mice

2009
The effect of carnosine treatment on prooxidant-antioxidant balance in liver, heart and brain tissues of male aged rats.
    Biogerontology, 2010, Volume: 11, Issue:1

    Topics: Aging; Animals; Antioxidants; Brain; Carnosine; Heart; Homeostasis; Liver; Male; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species

2010
NAD(+) and metabolic regulation of age-related proteoxicity: A possible role for methylglyoxal?
    Experimental gerontology, 2010, Volume: 45, Issue:6

    Topics: Aging; Animals; Caenorhabditis elegans; Carnosine; Cell Survival; Gene Expression Regulation; Glycation End Products, Advanced; Mitochondria; NAD; Neurons; Proteins; Pyruvaldehyde; Reactive Oxygen Species

2010
NT-020, a natural therapeutic approach to optimize spatial memory performance and increase neural progenitor cell proliferation and decrease inflammation in the aged rat.
    Rejuvenation research, 2010, Volume: 13, Issue:5

    Topics: Aging; Animals; Carnosine; Cell Proliferation; Cholecalciferol; Cognition; Dentate Gyrus; Dietary Supplements; Doublecortin Domain Proteins; Doublecortin Protein; Inflammation; Ki-67 Antigen; Male; Memory; Microglia; Microtubule-Associated Proteins; Neural Stem Cells; Neurogenesis; Neuropeptides; Plant Extracts; Rats; Rats, Inbred F344

2010
Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for cataract
    Cell biochemistry and function, 2011, Volume: 29, Issue:3

    Topics: Aged; Aging; Animals; Antioxidants; Aqueous Humor; Carnosine; Cataract; Female; Humans; Hydrogen Peroxide; Lens, Crystalline; Lipid Peroxidation; Lipid Peroxides; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mitochondria; Ophthalmic Solutions; Oxidation-Reduction; Oxidative Stress; Phospholipids; Prodrugs; Rabbits; Reactive Oxygen Species

2011
Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.
    PloS one, 2011, Mar-15, Volume: 6, Issue:3

    Topics: Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Carnosine; Chelating Agents; Cognition Disorders; Dietary Supplements; Hippocampus; Intracellular Space; Memory Disorders; Mice; Mice, Transgenic; Mitochondria; Neurons; tau Proteins; Zinc

2011
Synergistic effect of L-Carnosine and EGCG in the prevention of physiological brain aging.
    Current pharmaceutical design, 2013, Volume: 19, Issue:15

    Topics: Aging; Animals; Brain; Carnosine; Catechin; Cell Death; Drug Synergism; Female; Heme Oxygenase-1; HSP72 Heat-Shock Proteins; Humans; Oxidative Stress; Pregnancy; Rats; Rats, Wistar

2013
Carnosine modifies the incidence of genetically abnormal sex cells in the testes of senescence-accelerated mice.
    Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:1

    Topics: Aging; Animals; Carnosine; Cellular Senescence; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Spermatids; Spermatogonia; Testis

2002
Modification of the uterotropic effect produced by estrogens in aging rats.
    Bulletin of experimental biology and medicine, 2002, Volume: 134, Issue:5

    Topics: Acetylcysteine; Aging; Animals; Ascorbic Acid; Carnosine; DNA Damage; Endometrium; Estradiol; Female; Melatonin; Organ Size; Rats; Receptors, Progesterone; Swimming; Uterus; Vitamin E

2002
[Switching off the estrogen effect and approaches to its correction].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:8

    Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Carnosine; Cell Cycle; DNA Damage; Estradiol; Estrogen Receptor Modulators; Estrogens; Ethanol; Female; Fulvestrant; Gamma Rays; Melatonin; Organ Size; Ovariectomy; Physical Conditioning, Animal; Rats; Smoking; Swimming; Uterus; Vitamin D

2003
L-carnosine reduces telomere damage and shortening rate in cultured normal fibroblasts.
    Biochemical and biophysical research communications, 2004, Nov-12, Volume: 324, Issue:2

    Topics: Aging; beta-Galactosidase; Blotting, Southern; Carnosine; Cell Division; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Diploidy; DNA; Fibroblasts; Flow Cytometry; Humans; Reactive Oxygen Species; Sepharose; Telomere; Time Factors

2004
Carnosine-induced changes in the development of spermatogenic epithelial cells in senescence accelerated SAM mice.
    Bulletin of experimental biology and medicine, 2005, Volume: 140, Issue:2

    Topics: Aging; Animals; Carnosine; Cellular Senescence; Epithelial Cells; Male; Meiosis; Mice; Sertoli Cells; Spermatogenesis; Spermatozoa; Testis; Time Factors

2005
Carnosine, taurine and enzyme activities of human skeletal muscle fibres from elderly subjects with osteoarthritis and young moderately active subjects.
    Biogerontology, 2007, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; beta-Alanine; Carnosine; Citrate (si)-Synthase; Down-Regulation; Glycogen Phosphorylase; Histidine; Humans; Muscle Fibers, Fast-Twitch; Muscle Fibers, Skeletal; Muscle Fibers, Slow-Twitch; Osteoarthritis, Knee; Quadriceps Muscle; Taurine

2007
Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Aug-18, Volume: 123, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Cadmium; Carnosine; Child; Child, Preschool; Dipeptidases; Enzyme Activation; Humans; Infant; Isoelectric Point; Isoenzymes; Kinetics; Middle Aged; Molecular Weight; Substrate Specificity

1982
Ophidine (beta-alanyl-L-3-methylhistidine, "balenine') and other histidine dipeptides in pig muscles and tinned hams.
    Journal of the science of food and agriculture, 1982, Volume: 33, Issue:8

    Topics: Aging; Animals; Anserine; Carnosine; Dipeptides; Food Preservation; Meat; Muscles; Species Specificity; Swine

1982
Studies on homocarnosine in cerebrospinal fluid in infancy and childhood. Part I. Homocarnosine level in cerebrospinal fluid of normal infants and children.
    Brain & development, 1981, Volume: 3, Issue:3

    Topics: Aging; Carnosine; Child; Child, Preschool; Dipeptides; Female; Humans; Infant; Infant, Newborn; Male

1981
Olfactory bulb glycogen metabolism: noradrenergic modulation in the young rat.
    Brain research, 1995, Mar-20, Volume: 674, Issue:2

    Topics: Aging; Animals; Carnosine; Glycogen; Hydrolysis; Norepinephrine; Olfactory Bulb; Rats

1995
Carnosine, the protective, anti-aging peptide.
    Bioscience reports, 1999, Volume: 19, Issue:6

    Topics: Aging; Animals; Body Weight; Carnosine; Female; Hair; Male; Mice; Mice, Mutant Strains; Skin

1999
Carnosine reacts with a glycated protein.
    Free radical biology & medicine, 2000, May-15, Volume: 28, Issue:10

    Topics: Aging; Animals; Carnosine; Glycoproteins; Glycosylation; Humans; In Vitro Techniques; Lysine; Ovalbumin; Oxidation-Reduction; Pyruvaldehyde

2000
Carnosine as a potential anti-senescence drug.
    Biochemistry. Biokhimiia, 2000, Volume: 65, Issue:7

    Topics: Aging; Animals; Carnosine; Mice; Models, Animal

2000
Carnosine-like immunoreactivity in the central nervous system of rats during postnatal development.
    The Journal of comparative neurology, 2000, Oct-23, Volume: 426, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Carnosine; Central Nervous System; Immunohistochemistry; Male; Nerve Fibers; Neuroglia; Rats; Rats, Wistar; Spinal Cord

2000
Carnosine, the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups.
    Mechanisms of ageing and development, 2001, Sep-15, Volume: 122, Issue:13

    Topics: Aging; Animals; Antioxidants; Carnosine; Male; Ovalbumin; Pyruvaldehyde; Rats; Rats, Wistar

2001
Developmental changes and dietary histidine manipulation: effect on rat olfactory bulb and leg muscle components.
    The Journal of nutrition, 1978, Volume: 108, Issue:8

    Topics: Aging; Aminobutyrates; Animals; Anserine; Carnosine; Diet; Dipeptides; Female; gamma-Aminobutyric Acid; Hemoglobins; Histamine; Histidine; Male; Muscles; Nutritional Requirements; Olfactory Bulb; Pregnancy; Rats

1978
[Use of gamma-aminobutyric acid from various sources in the synthesis of homocarnosine in the brain of animals of various ages].
    Biokhimiia (Moscow, Russia), 1992, Volume: 57, Issue:9

    Topics: Aging; Animals; Brain; Carbon Radioisotopes; Carnosine; gamma-Aminobutyric Acid; Putrescine; Rats

1992
Carnosine content of the middle gluteal muscle in thoroughbred horses with relation to age, sex and training.
    Comparative biochemistry and physiology. A, Comparative physiology, 1989, Volume: 93, Issue:3

    Topics: Aging; Animals; Carnosine; Chromatography, High Pressure Liquid; Dipeptides; Female; Horses; Male; Muscles; Physical Conditioning, Animal; Reference Values; Sex Factors

1989
[Immunoregulative effects of homocarnosine and gamma-aminobuthyric acid].
    Nihon seirigaku zasshi. Journal of the Physiological Society of Japan, 1986, Volume: 48, Issue:6

    Topics: Aging; Animals; Antibody Formation; Carnosine; Dipeptides; gamma-Aminobutyric Acid; Homeostasis; Immunity; Immunity, Cellular; Mice; Mitomycin; Mitomycins; Wound Healing

1986