Page last updated: 2024-10-16

carnitine and Schizophrenia

carnitine has been researched along with Schizophrenia in 10 studies

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Our pilot study suggests that linoelaidyl carnitine levels at baseline may have a predictive role for the improvement of positive symptoms after OLA monotherapy in the patients with schizophrenia."8.12Plasma linoelaidyl carnitine levels positively correlated with symptom improvement in olanzapine-treated first-episode drug-naïve schizophrenia. ( Li, X; Su, X; Wang, K; Wang, X; Wu, F; Xiu, M, 2022)
"We sought to compare serum carnitine levels and clinical correlates between stable outpatients and acutely hospitalised individuals with diagnoses of bipolar disorder and schizophrenia."7.83Comparison of serum carnitine levels and clinical correlates between outpatients and acutely hospitalised individuals with bipolar disorder and schizophrenia: A cross-sectional study. ( Abramson, RK; Breen, RJ; Cuturic, M; Edwards, AC; Levy, EE, 2016)
"Subjects with schizophrenia have high risks of metabolic abnormalities and bioenergetic dysfunction."5.51Characterizing acyl-carnitine biosignatures for schizophrenia: a longitudinal pre- and post-treatment study. ( Brietzke, E; Cao, B; Huang, N; Mansur, RB; McIntyre, RS; Musial, N; Pan, Z; Subramanieapillai, M; Wang, D; Wang, J; Zeng, J, 2019)
"Our pilot study suggests that linoelaidyl carnitine levels at baseline may have a predictive role for the improvement of positive symptoms after OLA monotherapy in the patients with schizophrenia."4.12Plasma linoelaidyl carnitine levels positively correlated with symptom improvement in olanzapine-treated first-episode drug-naïve schizophrenia. ( Li, X; Su, X; Wang, K; Wang, X; Wu, F; Xiu, M, 2022)
"We sought to compare serum carnitine levels and clinical correlates between stable outpatients and acutely hospitalised individuals with diagnoses of bipolar disorder and schizophrenia."3.83Comparison of serum carnitine levels and clinical correlates between outpatients and acutely hospitalised individuals with bipolar disorder and schizophrenia: A cross-sectional study. ( Abramson, RK; Breen, RJ; Cuturic, M; Edwards, AC; Levy, EE, 2016)
"Subjects with schizophrenia have high risks of metabolic abnormalities and bioenergetic dysfunction."1.51Characterizing acyl-carnitine biosignatures for schizophrenia: a longitudinal pre- and post-treatment study. ( Brietzke, E; Cao, B; Huang, N; Mansur, RB; McIntyre, RS; Musial, N; Pan, Z; Subramanieapillai, M; Wang, D; Wang, J; Zeng, J, 2019)
"As carnitine deficiency is a potentially treatable condition further studies are warranted."1.37Clinical correlates of low serum carnitine levels in hospitalized psychiatric patients. ( Abramson, RK; Cuturic, M; Hall, AV; Hardin, JW; Moran, RR, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Wang, X1
Xiu, M1
Wang, K1
Su, X1
Li, X1
Wu, F1
Cao, B3
Chen, Y1
McIntyre, RS3
Yan, L1
Jin, M1
Brietzke, E2
Wang, D2
Rosenblat, JD1
Ragguett, RM1
Zhang, C1
Sun, X1
Rong, C1
Wang, J2
Wang, W1
Bai, M1
Jiang, T1
Li, C1
Li, P1
Zhou, H1
Wang, Z1
Li, L1
Jiang, H1
Costa, AC1
Joaquim, HPG1
Talib, LL1
Serpa, MH1
Zanetti, MV1
Gattaz, WF1
Pan, Z1
Musial, N1
Mansur, RB1
Subramanieapillai, M1
Zeng, J1
Huang, N1
Moos, WH1
Maneta, E1
Pinkert, CA1
Irwin, MH1
Hoffman, ME1
Faller, DV1
Steliou, K1
Cuturic, M2
Abramson, RK2
Breen, RJ1
Edwards, AC1
Levy, EE1
Moran, RR1
Hardin, JW1
Hall, AV1
Sonik, P1
Hilty, DM1
Rossaro, L1
Bourgeois, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy of L-Carnitine in the Management of Acute Clozapine Intoxication[NCT05632094]Phase 240 participants (Anticipated)Interventional2023-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for carnitine and Schizophrenia

ArticleYear
Epigenetic Treatment of Neuropsychiatric Disorders: Autism and Schizophrenia.
    Drug development research, 2016, Volume: 77, Issue:2

    Topics: Animals; Autism Spectrum Disorder; Carnitine; Epigenomics; Humans; Mitochondria; Neuroprotective Age

2016

Trials

1 trial available for carnitine and Schizophrenia

ArticleYear
Serum metabolic profiling using small molecular water-soluble metabolites in individuals with schizophrenia: A longitudinal study using a pre-post-treatment design.
    Psychiatry and clinical neurosciences, 2019, Volume: 73, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Antipsychotic Agents; Biomarkers; Carnitine; Female; Humans; Longitu

2019

Other Studies

8 other studies available for carnitine and Schizophrenia

ArticleYear
Plasma linoelaidyl carnitine levels positively correlated with symptom improvement in olanzapine-treated first-episode drug-naïve schizophrenia.
    Metabolomics : Official journal of the Metabolomic Society, 2022, 07-11, Volume: 18, Issue:7

    Topics: Carnitine; Humans; Metabolomics; Olanzapine; Pilot Projects; Schizophrenia

2022
Acyl-Carnitine plasma levels and their association with metabolic syndrome in individuals with schizophrenia.
    Psychiatry research, 2020, Volume: 293

    Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Female; Humans; Male; Metabolic Syndrome; Plasma

2020
Clozapine-induced reduction of l-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice.
    Toxicology and applied pharmacology, 2019, 01-15, Volume: 363

    Topics: Animals; Antipsychotic Agents; Carnitine; Cell Line; Chemical and Drug Induced Liver Injury; Clozapi

2019
Plasma metabolites in first episode psychoses.
    Schizophrenia research, 2019, Volume: 206

    Topics: Adolescent; Adult; Biomarkers; Bipolar Disorder; Carnitine; Female; Humans; Lysophosphatidylcholines

2019
Characterizing acyl-carnitine biosignatures for schizophrenia: a longitudinal pre- and post-treatment study.
    Translational psychiatry, 2019, 01-17, Volume: 9, Issue:1

    Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; China; Chromatography, Liquid; Energy Metabolism

2019
Comparison of serum carnitine levels and clinical correlates between outpatients and acutely hospitalised individuals with bipolar disorder and schizophrenia: A cross-sectional study.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2016, Volume: 17, Issue:6

    Topics: Adult; Bipolar Disorder; Carnitine; Cross-Sectional Studies; Female; Hospitalization; Humans; Inpati

2016
Clinical correlates of low serum carnitine levels in hospitalized psychiatric patients.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2011, Volume: 12, Issue:1

    Topics: Adult; Aged; Antimanic Agents; Carnitine; Female; Humans; Inpatients; Male; Mental Disorders; Middle

2011
Carnitine supplementation for valproate-related hyperammonemia to maintain therapeutic valproate level.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:5

    Topics: Adult; Anticonvulsants; Antisocial Personality Disorder; Carnitine; Humans; Hyperammonemia; Male; Sc

2011