carnitine has been researched along with Rett Syndrome in 7 studies
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 17-year-old girl with Rett syndrome, who was taking no other medications, was treated with L-carnitine (50 mg/kg/day)." | 7.68 | L-carnitine as a treatment for Rett syndrome. ( Kasnicka, I; Plioplys, AV, 1993) |
| "Rett syndrome is a severe neurodevelopmental disorder of unknown etiology, occurring almost exclusively in female patients." | 6.69 | Rett syndrome: randomized controlled trial of L-carnitine. ( Christodoulou, J; Ellaway, C; Higgins, G; Leonard, H; Wilcken, B; Williams, K, 1999) |
| "Very long-chain fatty acid and carnitine levels are decreased in Rett syndrome L-Carnitine administration increased very long-chain fatty acid levels in serum." | 3.70 | Very long-chain fatty acids in Rett syndrome. ( Bentkowski, Z; Stradomska, TJ; Tylki-Szymańska, A, 1999) |
| "A 17-year-old girl with Rett syndrome, who was taking no other medications, was treated with L-carnitine (50 mg/kg/day)." | 3.68 | L-carnitine as a treatment for Rett syndrome. ( Kasnicka, I; Plioplys, AV, 1993) |
| "Rett syndrome is a severe neurodevelopmental disorder of unknown etiology, occurring almost exclusively in female patients." | 2.69 | Rett syndrome: randomized controlled trial of L-carnitine. ( Christodoulou, J; Ellaway, C; Higgins, G; Leonard, H; Wilcken, B; Williams, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rana, KS | 1 |
| Nair, MN | 1 |
| Bao, XH | 1 |
| Pan, H | 1 |
| Song, FY | 1 |
| Wu, XR | 1 |
| Plioplys, AV | 1 |
| Kasnicka, I | 1 |
| Stradomska, TJ | 1 |
| Tylki-Szymańska, A | 1 |
| Bentkowski, Z | 1 |
| Ellaway, C | 1 |
| Williams, K | 2 |
| Leonard, H | 2 |
| Higgins, G | 1 |
| Wilcken, B | 1 |
| Christodoulou, J | 2 |
| Ellaway, CJ | 1 |
| Peat, J | 1 |
| Burd, L | 1 |
| Kemp, R | 1 |
| Knull, H | 1 |
| Loveless, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for carnitine and Rett Syndrome
| Article | Year |
|---|---|
A review of the biochemical pathways studied and abnormalities reported in the Rett syndrome.
Topics: Biogenic Amines; Carnitine; Energy Metabolism; Glutarates; Goals; Humans; Neurotransmitter Agents; R | 1990 |
2 trials available for carnitine and Rett Syndrome
| Article | Year |
|---|---|
Rett syndrome: randomized controlled trial of L-carnitine.
Topics: Adolescent; Adult; Carnitine; Child; Child, Preschool; Constipation; Cross-Over Studies; Double-Blin | 1999 |
Medium-term open label trial of L-carnitine in Rett syndrome.
Topics: Adolescent; Adult; Apraxias; Carnitine; Child; Female; Health Surveys; Humans; Recovery of Function; | 2001 |
4 other studies available for carnitine and Rett Syndrome
| Article | Year |
|---|---|
Rett's syndrome following bronchopneumonia.
Topics: Bronchopneumonia; Carnitine; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Fe | 2004 |
[Clinical feature of Rett syndrome and MeCP2 genotype/phenotype correlation analysis].
Topics: Adolescent; Carnitine; Child; Child, Preschool; Chromosomal Proteins, Non-Histone; DNA Mutational An | 2004 |
L-carnitine as a treatment for Rett syndrome.
Topics: Adolescent; Ammonia; Carnitine; Female; Humans; Rett Syndrome; Treatment Outcome | 1993 |
Very long-chain fatty acids in Rett syndrome.
Topics: Administration, Oral; Adolescent; Adult; Carnitine; Child; Child, Preschool; Fatty Acids; Female; Hu | 1999 |