Page last updated: 2024-10-16

carnitine and Reperfusion Injury

carnitine has been researched along with Reperfusion Injury in 43 studies

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to investigate possible protective effects of L-carnitine (carn) or atorvastatin (ator) on spinal cord ischemia-reperfusion injury (IRI)."8.02Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. ( Abdel-Razek, HAD; Abdou, AG; Hassan, MHA; Hazzaa, SM; Ibraheim, EO; Salem, EA, 2021)
"In conclusion, our data supports a protective effect of L-carnitine against oxidative damage in hepatic ischemia-reperfusion injury in rats."7.79The protective effect of L-carnitine on hepatic ischemia-reperfusion injury in rats. ( Aldemır, D; Boyacioğlu, S; Çekın, AH; Gür, G; Gürsoy, M; Taşkoparan, M; Türkoğlu, S; Yilmaz, U, 2013)
"Carnitine application prior to reperfusion may reduce the severity of the reperfusion injury by preventing the occurrence of no-reflow phenomenon, increase the number of perfused microvessels in the ischemic intestine, and may improve epithelial regeneration in intestinal anastomosis."7.76Carnitine protects the intestine against reperfusion injury in rats. ( Akhisaroglu, ST; Atila, K; Ergor, G; Hosgorler, FU; Kupelioglu, A; Oktay, G; Saydam, S; Terzi, C, 2010)
"To investigate the protective effects of L-carnitine upon testicular ischemia-reperfusion injury in rats."7.75[Protective effects of L-carnitine upon testicular ischemia-reperfusion damage in rats]. ( Guan, Y; Li, SW; Yang, ZW; Zheng, XM, 2009)
"The study aimed to examine whether L-carnitine and its derivatives, acetyl-L-carnitine and propionyl-L-carnitine, were equally effective and able to improve postischemic cardiac function, reduce the incidence of reperfusion-induced ventricular fibrillation, infarct size, and apoptotic cell death in ischemic/reperfused isolated rat hearts."7.72Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. ( Bertelli, A; Cui, J; Das, DK; Tosaki, A, 2003)
"Our results suggest that L-carnitine has beneficial effects on renal function, histopathologic changes, and survival in renal ischemia-reperfusion injury."7.72[The beneficial effect of L-carnitine in rat renal ischemia-reperfusion injury]. ( Astarcioğlu, H; Atila, K; Onal, A; Ormen, M; Sarioğlu, S, 2004)
" The aim of this study was to investigate the effect of carnitine in reperfusion injury of the kidney."7.71Carnitine as a preventive agent in experimental renal ischemia-reperfusion injury. ( Ergün, O; Kiliçalp, AS; Ulman, C; Ulman, I, 2001)
"The present study was designed to examine whether propionyl-l-carnitine, an acyl derivative of carnitine involved in fatty acid oxidation pathway and adenosine 5'-triphosphate (ATP) generation of mitochondria, prevented renal function deterioration and structural injury induced by ischemia-reperfusion in an ex vivo rat model of isolated perfused kidney (IPK) preparation and in vivo in a model of syngeneic kidney transplantation."7.71Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion. ( Abbate, M; Aiello, S; Arduini, A; Azzollini, N; Gagliardini, E; Mister, M; Noris, M; Perico, N; Remuzzi, G; Szymczuk, J; Trochimowicz, L, 2002)
" L-Propionyl carnitine (LPC), an endogenous ester that plays a crucial role in cellular fatty acid oxidation and metabolism, has been shown to exert a protective effect in myocardial ischemia/reperfusion injury."7.70L-propionyl carnitine, an endogenous ester in fatty acid metabolism, exerts anti-shock and endothelial protective effects in rat splanchnic ischemia-reperfusion injury. ( Amico-Roxas, M; Christopher, TA; Guo, YP; Lopez, BL; Ma, XL; Stroh, R, 1998)
"In this study we have examined the effect of propionyl-L-carnitine (PC) on rat spinal cord ischaemia and post-ischaemic reperfusion injury by evaluating two lipid peroxidation indices, thiobarbituric acid reactive substances (TBARS) and diene conjugation, before and after the addition of an ADP-Fe+2 complex to spinal cord homogenates."7.68Effect of propionyl-L-carnitine on rat spinal cord ischaemia and post-ischaemic reperfusion injury. ( Arduini, A; Belfiglio, M; Di Toppi, GS; Federici, G; Fernandez, E; Mancinelli, G; Pallini, R; Scurti, R, 1990)
"l-Carnitine pretreatment significantly increased tetanic contraction amplitude in the SOL muscles following I/R (P < ."5.39L-carnitine pretreatment protects slow-twitch skeletal muscles in a rat model of ischemia-reperfusion injury. ( Cerkez, C; Demirel, M; Ertunc, M; Kaya, B; Sara, Y, 2013)
"Treatment of L-carnitine 30 min prior to reperfusion significantly relieved I/R-induced metabolomic changes."5.38Metabolomic changes and protective effect of (L)-carnitine in rat kidney ischemia/reperfusion injury. ( Dai, W; Hu, W; Ji, C; Liu, Y; Mei, C; Yan, S; Zhang, W, 2012)
"Neurological injury because of transient cerebral ischemia is a potential complication of cardiovascular surgery."5.33Neuroprotective effects of L-carnitine and vitamin E alone or in combination against ischemia-reperfusion injury in rats. ( Aral, E; Aybek, H; Baltalarli, A; Baycu, C; Bir, LS; Coskun, E; Enli, Y; Oguz, EO; Onem, G; Ozcan, AV; Sacar, M, 2006)
"They were subjected to spinal cord ischemia by clamping the abdominal aorta for 45 min."5.32Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury. ( Ak, K; Akgun, S; Arsan, S; Civelek, A; Isbir, SC; Kurtkaya, O; Sav, A; Tekeli, A, 2004)
"L-carnitine treatment reduced these parameters to the values of sham operated rats."5.32L-carnitine protects gastric mucosa by decreasing ischemia-reperfusion induced lipid peroxidation. ( Agac, A; Aliciguzel, Y; Demir, N; Derin, N; Izgut-Uysal, VN, 2004)
"Spinal cord ischemia was induced by clamping the aorta both below the left renal artery and above the aortic bifurcation."5.31Neuroprotective effect of regional carnitine on spinal cord ischemia--reperfusion injury. ( Burma, O; Erol, FS; Ozercan, IH; Rahman, A; Ustündag, B, 2001)
"Two of the 7 animals in group III had spastic paraplegia, and none at all in group IV."5.31The effects of L-carnitine on spinal cord ischemia/reperfusion injury in rabbits. ( Atay, Y; Ayik, F; Calkavur, T; Canpolat, L; Islamoglu, F; Posacioglu, H; Tetik, O; Yagdi, T; Yuksel, M, 2002)
" The aim of the present study was to investigate possible protective effects of L-carnitine (carn) or atorvastatin (ator) on spinal cord ischemia-reperfusion injury (IRI)."4.02Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord. ( Abdel-Razek, HAD; Abdou, AG; Hassan, MHA; Hazzaa, SM; Ibraheim, EO; Salem, EA, 2021)
"In conclusion, our data supports a protective effect of L-carnitine against oxidative damage in hepatic ischemia-reperfusion injury in rats."3.79The protective effect of L-carnitine on hepatic ischemia-reperfusion injury in rats. ( Aldemır, D; Boyacioğlu, S; Çekın, AH; Gür, G; Gürsoy, M; Taşkoparan, M; Türkoğlu, S; Yilmaz, U, 2013)
"Carnitine application prior to reperfusion may reduce the severity of the reperfusion injury by preventing the occurrence of no-reflow phenomenon, increase the number of perfused microvessels in the ischemic intestine, and may improve epithelial regeneration in intestinal anastomosis."3.76Carnitine protects the intestine against reperfusion injury in rats. ( Akhisaroglu, ST; Atila, K; Ergor, G; Hosgorler, FU; Kupelioglu, A; Oktay, G; Saydam, S; Terzi, C, 2010)
"The purpose of this study was to investigate effects of carnitine administration on protein synthesis recovery after transient cerebral ischemia."3.75Effect of L-carnitine on postischemic inhibition of protein synthesis in the rat brain. ( Burda, J; Danielisová, V; Felipo, V; Hernández Viadel, M; Montoliu, C; Némethová, M, 2009)
"To investigate the protective effects of L-carnitine upon testicular ischemia-reperfusion injury in rats."3.75[Protective effects of L-carnitine upon testicular ischemia-reperfusion damage in rats]. ( Guan, Y; Li, SW; Yang, ZW; Zheng, XM, 2009)
"Our results suggest that L-carnitine has beneficial effects on renal function, histopathologic changes, and survival in renal ischemia-reperfusion injury."3.72[The beneficial effect of L-carnitine in rat renal ischemia-reperfusion injury]. ( Astarcioğlu, H; Atila, K; Onal, A; Ormen, M; Sarioğlu, S, 2004)
"The study aimed to examine whether L-carnitine and its derivatives, acetyl-L-carnitine and propionyl-L-carnitine, were equally effective and able to improve postischemic cardiac function, reduce the incidence of reperfusion-induced ventricular fibrillation, infarct size, and apoptotic cell death in ischemic/reperfused isolated rat hearts."3.72Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. ( Bertelli, A; Cui, J; Das, DK; Tosaki, A, 2003)
" The aim of this study was to investigate the effect of carnitine in reperfusion injury of the kidney."3.71Carnitine as a preventive agent in experimental renal ischemia-reperfusion injury. ( Ergün, O; Kiliçalp, AS; Ulman, C; Ulman, I, 2001)
"The present study was designed to examine whether propionyl-l-carnitine, an acyl derivative of carnitine involved in fatty acid oxidation pathway and adenosine 5'-triphosphate (ATP) generation of mitochondria, prevented renal function deterioration and structural injury induced by ischemia-reperfusion in an ex vivo rat model of isolated perfused kidney (IPK) preparation and in vivo in a model of syngeneic kidney transplantation."3.71Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion. ( Abbate, M; Aiello, S; Arduini, A; Azzollini, N; Gagliardini, E; Mister, M; Noris, M; Perico, N; Remuzzi, G; Szymczuk, J; Trochimowicz, L, 2002)
" L-Propionyl carnitine (LPC), an endogenous ester that plays a crucial role in cellular fatty acid oxidation and metabolism, has been shown to exert a protective effect in myocardial ischemia/reperfusion injury."3.70L-propionyl carnitine, an endogenous ester in fatty acid metabolism, exerts anti-shock and endothelial protective effects in rat splanchnic ischemia-reperfusion injury. ( Amico-Roxas, M; Christopher, TA; Guo, YP; Lopez, BL; Ma, XL; Stroh, R, 1998)
"In this study we have examined the effect of propionyl-L-carnitine (PC) on rat spinal cord ischaemia and post-ischaemic reperfusion injury by evaluating two lipid peroxidation indices, thiobarbituric acid reactive substances (TBARS) and diene conjugation, before and after the addition of an ADP-Fe+2 complex to spinal cord homogenates."3.68Effect of propionyl-L-carnitine on rat spinal cord ischaemia and post-ischaemic reperfusion injury. ( Arduini, A; Belfiglio, M; Di Toppi, GS; Federici, G; Fernandez, E; Mancinelli, G; Pallini, R; Scurti, R, 1990)
"L-carnitine or furosemide was administered, and serial blood samples were collected and analyzed to assess the effects of hydronephrosis on the pharmacokinetic parameters."1.56Rats with congenital hydronephrosis show increased susceptibility to renal ischemia-reperfusion injury. ( Cirule, H; Dambrova, M; Liepinsh, E; Sevostjanovs, E; Videja, M; Vilks, K; Vilskersts, R; Zharkova-Malkova, O, 2020)
"Levocarnitine plays a crucial role in the metabolism of organisms."1.51Effect of levocarnitine on cerebral ischemia-reperfusion rats via activating Nrf2/ARE signaling pathway. ( Liu, SH; Zhang, YC, 2019)
"l-Carnitine pretreatment significantly increased tetanic contraction amplitude in the SOL muscles following I/R (P < ."1.39L-carnitine pretreatment protects slow-twitch skeletal muscles in a rat model of ischemia-reperfusion injury. ( Cerkez, C; Demirel, M; Ertunc, M; Kaya, B; Sara, Y, 2013)
"Treatment of L-carnitine 30 min prior to reperfusion significantly relieved I/R-induced metabolomic changes."1.38Metabolomic changes and protective effect of (L)-carnitine in rat kidney ischemia/reperfusion injury. ( Dai, W; Hu, W; Ji, C; Liu, Y; Mei, C; Yan, S; Zhang, W, 2012)
"Ischemia-reperfusion injury is an important cause of graft failure."1.35Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation. ( Abbate, M; Arduini, A; Azzollini, N; Cassis, P; Cugini, D; Gagliardini, E; Noris, M; Peschechera, A; Pezzotta, A; Remuzzi, G, 2008)
"Neurological injury because of transient cerebral ischemia is a potential complication of cardiovascular surgery."1.33Neuroprotective effects of L-carnitine and vitamin E alone or in combination against ischemia-reperfusion injury in rats. ( Aral, E; Aybek, H; Baltalarli, A; Baycu, C; Bir, LS; Coskun, E; Enli, Y; Oguz, EO; Onem, G; Ozcan, AV; Sacar, M, 2006)
"They were subjected to spinal cord ischemia by clamping the abdominal aorta for 45 min."1.32Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury. ( Ak, K; Akgun, S; Arsan, S; Civelek, A; Isbir, SC; Kurtkaya, O; Sav, A; Tekeli, A, 2004)
"L-carnitine treatment reduced these parameters to the values of sham operated rats."1.32L-carnitine protects gastric mucosa by decreasing ischemia-reperfusion induced lipid peroxidation. ( Agac, A; Aliciguzel, Y; Demir, N; Derin, N; Izgut-Uysal, VN, 2004)
"Spinal cord ischemia was induced by clamping the aorta both below the left renal artery and above the aortic bifurcation."1.31Neuroprotective effect of regional carnitine on spinal cord ischemia--reperfusion injury. ( Burma, O; Erol, FS; Ozercan, IH; Rahman, A; Ustündag, B, 2001)
"Two of the 7 animals in group III had spastic paraplegia, and none at all in group IV."1.31The effects of L-carnitine on spinal cord ischemia/reperfusion injury in rabbits. ( Atay, Y; Ayik, F; Calkavur, T; Canpolat, L; Islamoglu, F; Posacioglu, H; Tetik, O; Yagdi, T; Yuksel, M, 2002)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (11.63)18.2507
2000's22 (51.16)29.6817
2010's12 (27.91)24.3611
2020's4 (9.30)2.80

Authors

AuthorsStudies
Liu, SH1
Zhang, YC1
Zhao, T1
Chen, S1
Wang, B1
Cai, D1
Vilskersts, R1
Vilks, K1
Videja, M1
Cirule, H1
Zharkova-Malkova, O1
Sevostjanovs, E1
Dambrova, M1
Liepinsh, E1
Todorović, Z1
Đurašević, S1
Stojković, M1
Grigorov, I1
Pavlović, S1
Jasnić, N1
Tosti, T1
Macut, JB1
Thiemermann, C1
Đorđević, J1
Hazzaa, SM1
Abdou, AG1
Ibraheim, EO1
Salem, EA1
Hassan, MHA1
Abdel-Razek, HAD1
Moghaddas, A2
Dashti-Khavidaki, S2
Çekın, AH1
Gür, G1
Türkoğlu, S1
Aldemır, D1
Yilmaz, U1
Gürsoy, M1
Taşkoparan, M1
Boyacioğlu, S1
Demirel, M1
Kaya, B1
Cerkez, C1
Ertunc, M1
Sara, Y1
Nativ, NI1
Yarmush, G1
So, A1
Barminko, J1
Maguire, TJ1
Schloss, R1
Berthiaume, F1
Yarmush, ML1
Banan, B1
Watson, R1
Xu, M1
Lin, Y1
Chapman, W1
Azzollini, N2
Cugini, D1
Cassis, P1
Pezzotta, A1
Gagliardini, E2
Abbate, M2
Arduini, A3
Peschechera, A1
Remuzzi, G2
Noris, M2
Hosgorler, FU1
Atila, K3
Terzi, C1
Akhisaroglu, ST1
Oktay, G1
Kupelioglu, A1
Ergor, G1
Saydam, S1
Jensen, PR1
Peitersen, T1
Karlsson, M1
In 't Zandt, R1
Gisselsson, A1
Hansson, G1
Meier, S1
Lerche, MH1
Guan, Y1
Zheng, XM1
Yang, ZW1
Li, SW1
Burda, J1
Hernández Viadel, M1
Danielisová, V1
Némethová, M1
Montoliu, C1
Felipo, V1
Bloomer, RJ1
Smith, WA1
Fisher-Wellman, KH1
Yuksel, S1
Sezer, MT1
Sahin, O1
Sutcu, R1
Koçogullari, C1
Yilmaz, HR1
Uz, E1
Kara, Y1
Aydin, B1
Altuntas, A1
Idrovo, JP1
Yang, WL1
Matsuda, A1
Nicastro, J1
Coppa, GF1
Wang, P1
Liu, Y1
Yan, S1
Ji, C1
Dai, W1
Hu, W1
Zhang, W1
Mei, C1
Coker, A1
Sagol, O1
Coker, I1
Topalak, O1
Astarcioglu, H2
Karademir, S1
Astarcioglu, I1
Varela, A1
Marina Prendes, MG1
Testoni, G1
Vázquez, N1
Astudilla, C1
Cerruti, S1
Savino, EA1
Wainwright, MS1
Mannix, MK1
Brown, J1
Stumpf, DA1
Cui, J1
Das, DK1
Bertelli, A2
Tosaki, A1
Akgun, S1
Tekeli, A1
Kurtkaya, O1
Civelek, A1
Isbir, SC1
Ak, K1
Arsan, S1
Sav, A1
Lang-Lazdunski, L1
Onal, A1
Ormen, M1
Sarioğlu, S1
Darçin, OT1
Baktiroğlu, L1
Ozkul, Y1
Ozardali, I1
Andaç, MH1
Derin, N1
Izgut-Uysal, VN1
Agac, A1
Aliciguzel, Y1
Demir, N1
Yonezawa, K1
Tolba, RH1
Wetter, A1
Yamamoto, Y1
Yamaoka, Y1
Minor, T1
Onem, G1
Aral, E1
Enli, Y1
Oguz, EO1
Coskun, E1
Aybek, H1
Ozcan, AV1
Sacar, M1
Bir, LS1
Baltalarli, A1
Baycu, C1
Hayashi, M1
Tomita, M1
Akin, M1
Kurukahvecioglu, O1
Gulbahar, O1
Isikgonul, I1
Taneri, F1
Tezel, E1
Onuk, E1
Usta, U1
Inan, M1
Erbas, H1
Aydogdu, N1
Oz Puyan, F1
Altaner, S1
Riva, E1
Leopaldi, D1
Stroh, R1
Christopher, TA1
Lopez, BL1
Guo, YP1
Amico-Roxas, M1
Ma, XL1
Calvani, M1
Arrigoni-Martelli, E1
Rahman, A1
Ustündag, B1
Burma, O1
Ozercan, IH1
Erol, FS1
Ergün, O1
Ulman, C1
Kiliçalp, AS1
Ulman, I1
Tetik, O1
Yagdi, T1
Islamoglu, F1
Calkavur, T1
Posacioglu, H1
Atay, Y1
Ayik, F1
Canpolat, L1
Yuksel, M1
Mister, M1
Szymczuk, J1
Aiello, S1
Trochimowicz, L1
Perico, N1
Conte, A1
Ronca, G1
Segnini, D1
Yu, G1
Fernandez, E1
Pallini, R1
Mancinelli, G1
Di Toppi, GS1
Belfiglio, M1
Scurti, R1
Federici, G1

Reviews

5 reviews available for carnitine and Reperfusion Injury

ArticleYear
Lipidomics Provides New Insight into Pathogenesis and Therapeutic Targets of the Ischemia-Reperfusion Injury.
    International journal of molecular sciences, 2021, Mar-10, Volume: 22, Issue:6

    Topics: Adipose Tissue; Animals; Carnitine; Fatty Acids; Humans; Lipidomics; Lipids; Mitochondria; Oxidative

2021
L-Carnitine and Potential Protective Effects Against Ischemia-Reperfusion Injury in Noncardiac Organs: From Experimental Data to Potential Clinical Applications.
    Journal of dietary supplements, 2018, Sep-03, Volume: 15, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carnitine; Female; Gastrointestinal Diseases; Human

2018
Potential protective effects of l-carnitine against neuromuscular ischemia-reperfusion injury: From experimental data to potential clinical applications.
    Clinical nutrition (Edinburgh, Scotland), 2016, Volume: 35, Issue:4

    Topics: Animals; Carnitine; Central Nervous System; Disease Models, Animal; Humans; Muscle, Skeletal; Reperf

2016
Mechanistic analysis for drug permeation through intestinal membrane.
    Drug metabolism and pharmacokinetics, 2007, Volume: 22, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bacterial Infections; Caco-2 Cells

2007
Attenuation by acetyl-L-carnitine of neurological damage and biochemical derangement following brain ischemia and reperfusion.
    International journal of tissue reactions, 1999, Volume: 21, Issue:1

    Topics: Acetylcarnitine; Animals; Brain; Brain Ischemia; Carnitine; Dogs; Oxidation-Reduction; Rats; Reperfu

1999

Trials

1 trial available for carnitine and Reperfusion Injury

ArticleYear
Oxidative stress in response to forearm ischemia-reperfusion with and without carnitine administration.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2010, Volume: 80, Issue:1

    Topics: Adult; Antioxidants; Biomarkers; Carnitine; Cross-Over Studies; Diet; Dietary Supplements; Double-Bl

2010

Other Studies

37 other studies available for carnitine and Reperfusion Injury

ArticleYear
Effect of levocarnitine on cerebral ischemia-reperfusion rats via activating Nrf2/ARE signaling pathway.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:18

    Topics: Animals; Antioxidant Response Elements; Apoptosis; Brain; Carnitine; Caspase 3; Heme Oxygenase (Decy

2019
L-Carnitine Reduces Myocardial Oxidative Stress and Alleviates Myocardial Ischemia-Reperfusion Injury by Activating Nuclear Transcription-Related Factor 2 (Nrf2)/Heme Oxygenase-1 (HO-1) Signaling Pathway.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, May-26, Volume: 26

    Topics: Animals; Apoptosis; Carnitine; Cell Hypoxia; Cell Survival; Heme Oxygenase (Decyclizing); Male; Malo

2020
Rats with congenital hydronephrosis show increased susceptibility to renal ischemia-reperfusion injury.
    Physiological reports, 2020, Volume: 8, Issue:22

    Topics: Acute Kidney Injury; Animals; Carnitine; Cell Adhesion Molecules; Disease Susceptibility; Diuretics;

2020
Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord.
    Journal of immunoassay & immunochemistry, 2021, Nov-02, Volume: 42, Issue:6

    Topics: Advanced Oxidation Protein Products; Animals; Atorvastatin; bcl-2-Associated X Protein; Carnitine; C

2021
The protective effect of L-carnitine on hepatic ischemia-reperfusion injury in rats.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2013, Volume: 24, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carnitine; Disease Models, Animal; Gluta

2013
L-carnitine pretreatment protects slow-twitch skeletal muscles in a rat model of ischemia-reperfusion injury.
    Vascular and endovascular surgery, 2013, Volume: 47, Issue:7

    Topics: Animals; Carnitine; Cytoprotection; Disease Models, Animal; Electric Stimulation; Male; Muscle Contr

2013
Elevated sensitivity of macrosteatotic hepatocytes to hypoxia/reoxygenation stress is reversed by a novel defatting protocol.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2014, Volume: 20, Issue:8

    Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Carnitine; Cytosol; Fatty Liver; Hepatocytes; Hy

2014
Development of a normothermic extracorporeal liver perfusion system toward improving viability and function of human extended criteria donor livers.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2016, Volume: 22, Issue:7

    Topics: Adult; Aged; Allografts; Biopsy, Large-Core Needle; Carnitine; Donor Selection; Exenatide; Fatty Liv

2016
Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation.
    Kidney international, 2008, Volume: 74, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Cyclosporine; Graft Survival; Kidney Co

2008
Carnitine protects the intestine against reperfusion injury in rats.
    The Journal of surgical research, 2010, Volume: 159, Issue:1

    Topics: Anastomosis, Surgical; Animals; Carnitine; Collagen; Intestines; Malondialdehyde; Nitric Oxide; Rats

2010
Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo.
    The Journal of biological chemistry, 2009, Dec-25, Volume: 284, Issue:52

    Topics: Acetylcarnitine; Animals; Carnitine; Citric Acid Cycle; Coenzyme A; Coenzyme A Ligases; Energy Metab

2009
[Protective effects of L-carnitine upon testicular ischemia-reperfusion damage in rats].
    Zhonghua yi xue za zhi, 2009, Jul-14, Volume: 89, Issue:26

    Topics: Animals; Apoptosis; Carnitine; Heat-Shock Proteins; Ischemia; Male; Rats; Rats, Sprague-Dawley; Repe

2009
Effect of L-carnitine on postischemic inhibition of protein synthesis in the rat brain.
    General physiology and biophysics, 2009, Volume: 28, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Carnitine; Cerebral Cortex; Corpus Striatum; Hippocampus; Nerve Dege

2009
The role of carnitine in preventing renal damage developed as a result of infrarenal aortic ischemia-reperfusion.
    Renal failure, 2011, Volume: 33, Issue:4

    Topics: Acute Kidney Injury; Animals; Aorta, Abdominal; Carnitine; Kidney; Male; Random Allocation; Rats; Ra

2011
Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injury.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:1

    Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Carnitine; Carnitine O-Palmitoyltransfe

2012
Metabolomic changes and protective effect of (L)-carnitine in rat kidney ischemia/reperfusion injury.
    Kidney & blood pressure research, 2012, Volume: 35, Issue:5

    Topics: Acute Kidney Injury; Animals; Carnitine; Disease Models, Animal; Energy Metabolism; Male; Malondiald

2012
Protective effects of carnitine in an experimental ischemia-reperfusion injury.
    Clinical nutrition (Edinburgh, Scotland), 2002, Volume: 21, Issue:4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carnitine; Disease Models, Animal; Femal

2002
Influence of fasting on the effects of ischemic preconditioning in the ischemic-reperfused rat heart.
    Archives of physiology and biochemistry, 2002, Volume: 110, Issue:3

    Topics: Animals; Carnitine; Female; Food Deprivation; Heart; Ischemic Preconditioning, Myocardial; Male; Oxy

2002
L-carnitine reduces brain injury after hypoxia-ischemia in newborn rats.
    Pediatric research, 2003, Volume: 54, Issue:5

    Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Carnitine; Female; Humans; Hypoxia-Ischemia, Brain

2003
Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts.
    Molecular and cellular biochemistry, 2003, Volume: 254, Issue:1-2

    Topics: Acetylcarnitine; Animals; Apoptosis; Cardiotonic Agents; Carnitine; Heart; Ischemia; Myocardium; Myo

2003
Neuroprotective effects of FK-506, L-carnitine and azathioprine on spinal cord ischemia-reperfusion injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 25, Issue:1

    Topics: Animals; Azathioprine; Carnitine; Drug Therapy, Combination; Immunohistochemistry; Immunosuppressive

2004
About the neuroprotective effects of FK-506, l-carnitine and azathioprine on spinal cord ischemia-reperfusion injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 25, Issue:6

    Topics: Animals; Azathioprine; Carnitine; Neuroprotective Agents; Rats; Reperfusion Injury; Spinal Cord Isch

2004
[The beneficial effect of L-carnitine in rat renal ischemia-reperfusion injury].
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2004, Volume: 10, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Carnitine; Creatinine; Kidney; Protective Agents; Rats; Rats, Wistar;

2004
Prevention of postischemic spinal cord injury by means of regional infusion of adenosine and L-carnitine dissolved in normothermic saline.
    Annals of vascular surgery, 2004, Volume: 18, Issue:3

    Topics: Adenosine; Animals; Axons; Blood Pressure; Carnitine; Disease Models, Animal; Female; Infusions, Int

2004
L-carnitine protects gastric mucosa by decreasing ischemia-reperfusion induced lipid peroxidation.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2004, Volume: 55, Issue:3

    Topics: Animals; Carnitine; Catalase; Dinoprostone; Gastric Mucosa; Glutathione Peroxidase; Glycosaminoglyca

2004
L-carnitine could not improve hepatic warm ischemia-reperfusion injury despite ameliorated blood flow.
    The Journal of surgical research, 2005, May-01, Volume: 125, Issue:1

    Topics: Alanine Transaminase; Animals; Apoptosis; Blood Glucose; Carnitine; L-Lactate Dehydrogenase; Liver;

2005
Neuroprotective effects of L-carnitine and vitamin E alone or in combination against ischemia-reperfusion injury in rats.
    The Journal of surgical research, 2006, Volume: 131, Issue:1

    Topics: Animals; Antioxidants; Brain; Brain Diseases; Brain Ischemia; Carnitine; Drug Therapy, Combination;

2006
Comparison of the effects of sodium nitroprusside and L-carnitine in experimental ischemia-reperfusion injury in rats.
    Transplantation proceedings, 2007, Volume: 39, Issue:10

    Topics: Animals; Carnitine; Disease Models, Animal; Male; Mesenteric Arteries; Nitroprusside; Rats; Rats, Wi

2007
Tissue damage in rat ovaries subjected to torsion and detorsion: effects of L-carnitine and N-acetyl cysteine.
    Pediatric surgery international, 2008, Volume: 24, Issue:5

    Topics: Acetylcysteine; Animals; Carnitine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Femal

2008
Control of the cardiac consequences of myocardial ischemia and reperfusion by L-propionylcarnitine: age-response and dose-response studies in the rat heart.
    Pediatric research, 1993, Volume: 34, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Carnitine; Coronary Circulation; Dose-Response

1993
L-propionyl carnitine, an endogenous ester in fatty acid metabolism, exerts anti-shock and endothelial protective effects in rat splanchnic ischemia-reperfusion injury.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:3

    Topics: Animals; Blood Pressure; Carnitine; Endothelium, Vascular; Fatty Acids; Intestines; Male; Mesenteric

1998
Neuroprotective effect of regional carnitine on spinal cord ischemia--reperfusion injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2001, Volume: 20, Issue:1

    Topics: Animals; Carnitine; Female; Infusions, Intra-Arterial; Male; Malondialdehyde; Neuroprotective Agents

2001
Carnitine as a preventive agent in experimental renal ischemia-reperfusion injury.
    Urological research, 2001, Volume: 29, Issue:3

    Topics: Animals; Carnitine; Kidney; Male; Rabbits; Reperfusion Injury

2001
The effects of L-carnitine on spinal cord ischemia/reperfusion injury in rabbits.
    The Thoracic and cardiovascular surgeon, 2002, Volume: 50, Issue:1

    Topics: Animals; Carnitine; Infusions, Intra-Arterial; Isotonic Solutions; Models, Animal; Paraplegia; Rabbi

2002
Propionyl-L-carnitine prevents renal function deterioration due to ischemia/reperfusion.
    Kidney international, 2002, Volume: 61, Issue:3

    Topics: Animals; Carnitine; In Vitro Techniques; Ischemia; Kidney; Kidney Transplantation; Male; Rats; Rats,

2002
Protective effect of propionyl carnitine against peroxidative damage to arterial endothelium membranes.
    International journal of tissue reactions, 1991, Volume: 13, Issue:1

    Topics: Animals; Carnitine; Cattle; Cell Membrane; Cell Separation; Dose-Response Relationship, Drug; Endoth

1991
Effect of propionyl-L-carnitine on rat spinal cord ischaemia and post-ischaemic reperfusion injury.
    Free radical research communications, 1990, Volume: 10, Issue:6

    Topics: Animals; Carnitine; Free Radicals; In Vitro Techniques; Ischemia; Lipid Peroxidation; Male; Rats; Ra

1990