Page last updated: 2024-10-16

carnitine and Pervasive Child Development Disorders

carnitine has been researched along with Pervasive Child Development Disorders in 5 studies

Research Excerpts

ExcerptRelevanceReference
"Disorders of carnitine biosynthesis have recently been associated with neurodevelopmental syndromes such as autism spectrum disorder (ASD)."7.81Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation. ( Beaudet, AL; Comeaux, MS; Elsea, SH; Scaglia, F; Schaaf, CP; Sun, Q; Yang, Y; Ziats, MN, 2015)
"Disorders of carnitine biosynthesis have recently been associated with neurodevelopmental syndromes such as autism spectrum disorder (ASD)."3.81Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation. ( Beaudet, AL; Comeaux, MS; Elsea, SH; Scaglia, F; Schaaf, CP; Sun, Q; Yang, Y; Ziats, MN, 2015)
"L-carnitine was proposed as a potential treatment for patients diagnosed with an autism spectrum disorder to improve mitochondrial dysfunction, but no prior randomized controlled trials have been conducted."2.76A prospective double-blind, randomized clinical trial of levocarnitine to treat autism spectrum disorders. ( Adams, JB; Davis, G; Geier, DA; Geier, MR; Kern, JK; King, PG; Young, JL, 2011)
"Autism spectrum disorder (ASD) with intellectual disability (ID) is a life-long debilitating condition, which is characterized by cognitive function impairment and other neurological signs."1.42Autism and intellectual disability associated with mitochondrial disease and hyperlactacidemia. ( Cauli, O; González-Guevara, L; Guevara-Campos, J, 2015)
"Acyl-carnitine panels were determined to be abnormal if three or more individual acyl-carnitine species were abnormal in the panel and these abnormalities were verified by repeated testing."1.39Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder. ( Frye, RE; Macfabe, DF; Melnyk, S, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guevara-Campos, J1
González-Guevara, L1
Cauli, O1
Ziats, MN1
Comeaux, MS1
Yang, Y1
Scaglia, F1
Elsea, SH1
Sun, Q1
Beaudet, AL1
Schaaf, CP1
Thomas, RH1
Foley, KA1
Mepham, JR1
Tichenoff, LJ1
Possmayer, F1
MacFabe, DF2
Geier, DA1
Kern, JK1
Davis, G1
King, PG1
Adams, JB1
Young, JL1
Geier, MR1
Frye, RE1
Melnyk, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Chart Review to Evaluate the Safety and Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on Subjects With Autism Spectrum Disorder (ASD)[NCT02758496]141 participants (Actual)Observational2016-04-30Completed
A Longitudinal Study on the Safety and Efficacy for Subjects With Autism Spectrum Disorder (ASD) Who Received Magnetic EEG/ECG-Guided Resonance Therapy (MeRT)[NCT02746445]11 participants (Actual)Observational2016-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for carnitine and Pervasive Child Development Disorders

ArticleYear
A prospective double-blind, randomized clinical trial of levocarnitine to treat autism spectrum disorders.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:6

    Topics: Carnitine; Child; Child Development Disorders, Pervasive; Child, Preschool; Cognition; Cohort Studie

2011

Other Studies

4 other studies available for carnitine and Pervasive Child Development Disorders

ArticleYear
Autism and intellectual disability associated with mitochondrial disease and hyperlactacidemia.
    International journal of molecular sciences, 2015, Feb-11, Volume: 16, Issue:2

    Topics: Carnitine; Child Development Disorders, Pervasive; Child, Preschool; Female; Folic Acid; Humans; Hyp

2015
Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation.
    American journal of medical genetics. Part A, 2015, Volume: 167A, Issue:9

    Topics: Autism Spectrum Disorder; Autistic Disorder; Cardiomyopathies; Carnitine; Child Development Disorder

2015
Altered brain phospholipid and acylcarnitine profiles in propionic acid infused rodents: further development of a potential model of autism spectrum disorders.
    Journal of neurochemistry, 2010, Volume: 113, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Carnitine; Child; Child Development Disorders, Pervasive; Chromato

2010
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013