Page last updated: 2024-10-16

carnitine and Overweight

carnitine has been researched along with Overweight in 33 studies

Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.

Research Excerpts

ExcerptRelevanceReference
"12-week L-carnitine supplementation in overweight or obese women with PCOS ameliorate insulin resistance, but has no effect on SHBG and lipid profile."9.51The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial. ( Fallahzadeh, H; Ghadiri-Anari, A; Hosseinzadeh, M; Nadjarzadeh, A; Pakravanfar, F; Sangouni, AA, 2022)
"The present study aimed to investigate the effect of l-carnitine supplementation on liver fat content and cardiometabolic outcomes in overweight/obese women with PCOS."9.41Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial. ( Ghadiri-Anari, A; Hosseinzadeh, M; Sangouni, AA; Sasanfar, B, 2021)
"In a prospective, randomized, double-blind, placebo-controlled trial, 60 overweight patients diagnosed with PCOS were randomized to receive either 250 mg carnitine supplements (n = 30) or placebo (n = 30) for 12 weeks."9.22Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. ( Asemi, Z; Ebrahimi, FA; Jamilian, M; Rahimi, M; Samimi, M; Tajbakhsh, B, 2016)
" Lower carnitine concentrations were found in overweight compared to lean dogs."7.91Plasma metabolomics reveals lower carnitine concentrations in overweight Labrador Retriever dogs. ( Dicksved, J; Eriksson Röhnisch, H; Hagman, R; Höglund, K; Moazzami, AA; Söder, J; Wernersson, S, 2019)
"Circulating acyl-carnitines (acyl-CNTs) are associated with insulin resistance (IR) and type 2 diabetes (T2D) in both rodents and humans."7.85Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women. ( Abate, N; Asghar, R; Brasier, AR; Camacho-Hughes, M; Chondronikola, M; Dillon, EL; Durham, WJ; Porter, C; Sheffield-Moore, M; Sidossis, L; Tuvdendorj, D; Volpi, E; Wu, Z; Zhang, X; Zhao, Y, 2017)
"The crucial role of L-carnitine in pregnancy metabolism suggests that nutritional supplementation of this amino acid can be offered to women who are either overweight or obese at the beginning of the pregnancy."7.79Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tipi-Akbas, P; Yilmazer, M, 2013)
"To investigate the influence of dietary supplementation with l-carnitine on metabolic rate, fatty acid oxidation, weight loss, and lean body mass (LBM) in overweight cats undergoing rapid weight reduction."7.78Influence of dietary supplementation with (L)-carnitine on metabolic rate, fatty acid oxidation, body condition, and weight loss in overweight cats. ( Center, SA; Randolph, JF; Sunvold, GD; Vickers, JR; Warner, KL, 2012)
"Overweight patients with hyperlipidemia (serum triglyceride ≥ 1."6.80Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. ( Du, S; Jiang, S; Li, Y; Na, L; Niu, Y; Sun, C; Zhang, Q; Zhang, W, 2015)
"12-week L-carnitine supplementation in overweight or obese women with PCOS ameliorate insulin resistance, but has no effect on SHBG and lipid profile."5.51The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial. ( Fallahzadeh, H; Ghadiri-Anari, A; Hosseinzadeh, M; Nadjarzadeh, A; Pakravanfar, F; Sangouni, AA, 2022)
"The present study aimed to investigate the effect of l-carnitine supplementation on liver fat content and cardiometabolic outcomes in overweight/obese women with PCOS."5.41Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial. ( Ghadiri-Anari, A; Hosseinzadeh, M; Sangouni, AA; Sasanfar, B, 2021)
"Our findings underscore the importance of changes in TMAO, choline and L-carnitine in improving insulin sensitivity during a weight-loss intervention for obese patients."5.30Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. ( Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D, 2019)
" We examined associations of weight loss diet-induced changes in a gut microbiota-related metabolite trimethylamine N-oxide (TMAO), and its precursors (choline and l-carnitine), with changes in bone mineral density (BMD) considering diabetes-related factors."5.30Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T, 2019)
"In a prospective, randomized, double-blind, placebo-controlled trial, 60 overweight patients diagnosed with PCOS were randomized to receive either 250 mg carnitine supplements (n = 30) or placebo (n = 30) for 12 weeks."5.22Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. ( Asemi, Z; Ebrahimi, FA; Jamilian, M; Rahimi, M; Samimi, M; Tajbakhsh, B, 2016)
"This randomized, double blind, placebo-controlled, 8 week trial assessed the efficacy on metabolic changes produced by a consumption of a combination of bioactive food ingredients (epigallocatechin gallate, capsaicins, piperine and L-carnitine) versus a placebo, as part of a therapeutic 'lifestyle change' diet, in 86 overweight subjects."5.17Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months' consumption of a combination of bioactive food ingredients in overweight subjects. ( Castellaneta, E; Cava, E; Ceccarelli, P; Claudia, S; Donini, LM; Edda, C; Emanuela, C; Faliva, M; Fioravanti, M; Klersy, C; Luciano, S; Maddalena, P; Opizzi, A; Paola, C; Paolini, M; Perna, S; Rondanelli, M; Savina, C; Scavone, L; Solerte, SB, 2013)
"Plasma carnitine status was overall lower in spontaneously overweight dogs than in lean dogs in this cohort of healthy Labrador Retriever dogs, indicating a potential carnitine insufficiency in the overweight group."3.91Indication of metabolic inflexibility to food intake in spontaneously overweight Labrador Retriever dogs. ( Dicksved, J; Hagman, R; Höglund, K; Moazzami, AA; Östman, JR; Söder, J; Wernersson, S, 2019)
"Circulating acyl-carnitines (acyl-CNTs) are associated with insulin resistance (IR) and type 2 diabetes (T2D) in both rodents and humans."3.85Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women. ( Abate, N; Asghar, R; Brasier, AR; Camacho-Hughes, M; Chondronikola, M; Dillon, EL; Durham, WJ; Porter, C; Sheffield-Moore, M; Sidossis, L; Tuvdendorj, D; Volpi, E; Wu, Z; Zhang, X; Zhao, Y, 2017)
"The crucial role of L-carnitine in pregnancy metabolism suggests that nutritional supplementation of this amino acid can be offered to women who are either overweight or obese at the beginning of the pregnancy."3.79Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tipi-Akbas, P; Yilmazer, M, 2013)
"To investigate the influence of dietary supplementation with l-carnitine on metabolic rate, fatty acid oxidation, weight loss, and lean body mass (LBM) in overweight cats undergoing rapid weight reduction."3.78Influence of dietary supplementation with (L)-carnitine on metabolic rate, fatty acid oxidation, body condition, and weight loss in overweight cats. ( Center, SA; Randolph, JF; Sunvold, GD; Vickers, JR; Warner, KL, 2012)
"Higher acylcarnitine factor scores were associated with lower levels of objectively measured physical performance in this group of older, largely overweight men."3.77Plasma acylcarnitines are associated with physical performance in elderly men. ( Bain, JR; Cohen, HJ; Huffman, KM; Kraus, VB; Kraus, WE; Lum, H; Morey, MC; Newgard, CB; Pieper, CF; Sloane, R; Stevens, R; Taylor, GA; Thompson, DK, 2011)
"Overweight patients with hyperlipidemia (serum triglyceride ≥ 1."2.80Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. ( Du, S; Jiang, S; Li, Y; Na, L; Niu, Y; Sun, C; Zhang, Q; Zhang, W, 2015)
"Hyperlipidemia and obesity are associated with metabolic syndrome and increased risk in developing diabetes and cardiovascular disease."2.76A combination of (ω-3) polyunsaturated fatty acids, polyphenols and L-carnitine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation in human peripheral blood mononuclear cells and HepG2 cells. ( Anderwald, C; Anzur, C; Brachinger, M; Eller-Berndl, D; Fischer, A; Krepp, R; Laschan, C; Lechner, S; Lienbacher, G; Lohninger, A; Mascher, D; Radler, U; Schoerg, G; Stangl, H; Zeller, E, 2011)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.03)29.6817
2010's26 (78.79)24.3611
2020's6 (18.18)2.80

Authors

AuthorsStudies
Ma, Y1
Sun, Y1
Sun, L1
Liu, X1
Zeng, R1
Lin, X1
Li, Y2
Sangouni, AA2
Pakravanfar, F1
Ghadiri-Anari, A2
Nadjarzadeh, A1
Fallahzadeh, H1
Hosseinzadeh, M2
Sasanfar, B1
Rastgoo, S1
Fateh, ST1
Nikbaf-Shandiz, M1
Rasaei, N1
Aali, Y1
Zamani, M1
Shiraseb, F1
Asbaghi, O1
Kim, KW1
Shin, WC1
Choi, MS1
Cho, JH1
Park, HJ1
Yoo, HH1
Song, MY1
Rico, JE1
Zang, Y1
Haughey, NJ1
Rius, AG1
McFadden, JW1
Heianza, Y2
Sun, D2
Li, X2
DiDonato, JA2
Bray, GA2
Sacks, FM2
Qi, L2
Kang, M2
Yoo, HJ2
Kim, M5
Lee, JH3
Söder, J2
Höglund, K2
Dicksved, J2
Hagman, R2
Eriksson Röhnisch, H1
Moazzami, AA2
Wernersson, S2
Östman, JR1
Jamilian, M2
Foroozanfard, F1
Kavossian, E1
Kia, M1
Aghadavod, E1
Amirani, E1
Asemi, Z2
Zhou, T1
Chen, Y1
Pei, X1
LeBoff, MS1
Tipi-Akbas, P1
Arioz, DT1
Kanat-Pektas, M1
Koken, T1
Koken, G1
Yilmazer, M1
Patel, MJ1
Batch, BC1
Svetkey, LP1
Bain, JR5
Turer, CB1
Haynes, C1
Muehlbauer, MJ3
Stevens, RD4
Newgard, CB5
Shah, SH2
Larsen, S1
Danielsen, JH1
Søndergård, SD1
Søgaard, D1
Vigelsoe, A1
Dybboe, R1
Skaaby, S1
Dela, F1
Helge, JW1
Jung, S1
Lee, SH1
Fiamoncini, J1
Lima, TM1
Hirabara, SM1
Ecker, J1
Gorjão, R1
Romanatto, T1
ELolimy, A1
Worsch, S1
Laumen, H1
Bader, B1
Daniel, H1
Curi, R1
Na, L1
Zhang, Q1
Jiang, S1
Du, S1
Zhang, W1
Sun, C1
Niu, Y1
Malek Mahdavi, A1
Mahdavi, R1
Kolahi, S1
Zemestani, M1
Vatankhah, AM1
Samimi, M1
Ebrahimi, FA1
Rahimi, M1
Tajbakhsh, B1
Allam-Ndoul, B1
Guénard, F1
Garneau, V1
Cormier, H1
Barbier, O1
Pérusse, L1
Vohl, MC1
Chondronikola, M1
Asghar, R1
Zhang, X1
Dillon, EL1
Durham, WJ1
Wu, Z1
Porter, C1
Camacho-Hughes, M1
Zhao, Y1
Brasier, AR1
Volpi, E1
Sheffield-Moore, M1
Abate, N1
Sidossis, L1
Tuvdendorj, D1
Tovar, J1
de Mello, VD1
Nilsson, A1
Johansson, M1
Paananen, J1
Lehtonen, M1
Hanhineva, K1
Björck, I1
Bobillo, C1
Finlayson, G1
Martínez, A1
Fischman, D1
Beneitez, A1
Ferrero, AJ1
Fernández, BE1
Mayer, MA1
Kim, MS1
Ahn, YT1
Sim, JH1
Jee, SH1
Huffman, KM4
Muehlbauer, M1
Slentz, CA1
Tanner, CJ1
Kuchibhatla, M1
Houmard, JA1
Kraus, WE4
Redman, LM2
Landerman, LR2
Pieper, CF3
Wenner, BR2
Kraus, VB3
Ravussin, E2
Lum, H1
Sloane, R1
Thompson, DK1
Stevens, R1
Taylor, GA1
Cohen, HJ1
Morey, MC1
Radler, U1
Stangl, H1
Lechner, S1
Lienbacher, G1
Krepp, R1
Zeller, E1
Brachinger, M1
Eller-Berndl, D1
Fischer, A1
Anzur, C1
Schoerg, G1
Mascher, D1
Laschan, C1
Anderwald, C1
Lohninger, A1
Ramos-Roman, MA1
Sweetman, L1
Valdez, MJ1
Parks, EJ1
Center, SA1
Warner, KL1
Randolph, JF1
Sunvold, GD1
Vickers, JR1
Rondanelli, M1
Opizzi, A1
Perna, S1
Faliva, M1
Solerte, SB1
Fioravanti, M1
Klersy, C1
Cava, E1
Edda, C1
Paolini, M1
Maddalena, P1
Scavone, L1
Luciano, S1
Ceccarelli, P1
Paola, C1
Castellaneta, E1
Emanuela, C1
Savina, C1
Claudia, S1
Donini, LM1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Low-Carbohydrate or Restricted-Calories Diet on Body Weight[NCT01358890]Phase 2/Phase 350 participants (Actual)Interventional2011-05-31Completed
Effects of Acupuncture on Serum Metabolic Parameters in Pre-menopausal Obese Women: A Randomized Controlled Trial[NCT02066090]120 participants (Actual)Interventional2014-03-31Completed
Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)[NCT00072995]811 participants Interventional2003-09-30Completed
Metabolomics Identifies Increases in Acylcarnitine Profiles in Plasma of Overweight Subjects in Response to Mild Weight Loss[NCT03135132]100 participants (Actual)Interventional2015-06-30Completed
Efficacy of Vitamin C Supplement Addiction vs. High-speed Spinal Manipulation to Routine Physiotherapy Treatment in Lateral Epicondylitis[NCT04445727]130 participants (Actual)Interventional2020-05-21Enrolling by invitation
Calorie Restriction Intervention Induces Enterotype-associated BMI Loss in Nonobese Individuals[NCT04044118]41 participants (Actual)Interventional2017-04-01Completed
Life 2: Improving Fitness and Function in Elders[NCT00435188]400 participants (Actual)Interventional2004-11-30Completed
Pilot Study to Test Dietary Fat Delivery[NCT02101996]9 participants (Actual)Observational2014-06-30Completed
Effect of Dietary Macronutrient Composition on Liver Substrate Metabolism[NCT01371396]24 participants (Actual)Interventional2007-09-01Completed
Metabolic Adaptations to Six Month Caloric Restriction[NCT00099151]48 participants Interventional2002-03-31Completed
Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE)[NCT00427193]238 participants (Actual)Interventional2007-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

2 Minute Walk

Distance walked in two minutes in meters (NCT00435188)
Timeframe: 12 month

Interventionmeters (Mean)
Arm 1150.9
Arm 2147.5

2 Minute Walk

Distance walked in two minutes in meters (NCT00435188)
Timeframe: 3 month

Interventionmeters (Mean)
Arm 1151.7
Arm 2145.6

2 Minute Walk

Distance walked in two minutes in meters (NCT00435188)
Timeframe: Baseline

Interventionmeters (Mean)
Arm 1146
Arm 2145.4

Physical Activity Frequency (CHAMPS Questionnaire)

Exercise frequency derived from Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire; The Champs assesses the frequency of a range of physical activities (NCT00435188)
Timeframe: 12 month

Interventiontimes per week (Mean)
Arm 1, Physical Activity Counseling22.4
Arm 2, Usual Care16.8

Physical Activity Frequency (CHAMPS Questionnaire)

Exercise frequency derived from Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire; The Champs assesses the frequency of a range of physical activities (NCT00435188)
Timeframe: 3 month

Interventiontimes per week (Mean)
Arm 1, Physical Activity Counseling22.7
Arm 2, Usual Care17.6

Physical Activity Frequency (CHAMPS Questionnaire)

Exercise frequency derived from Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire; The Champs assesses the frequency of a range of physical activities (NCT00435188)
Timeframe: Baseline

Interventiontimes per week (Mean)
Arm 1, Physical Activity Counseling15.9
Arm 2, Usual Care16.8

Rapid Gait Speed

(NCT00435188)
Timeframe: 12-month

Interventionmeters/second (Mean)
Arm 11.68
Arm 21.59

Rapid Gait Speed

(NCT00435188)
Timeframe: 3-month

Interventionmeters/second (Mean)
Arm 11.62
Arm 21.58

Rapid Gait Speed

(NCT00435188)
Timeframe: Baseline

Interventionmeters/second (Mean)
Arm 11.56
Arm 21.57

Sf-36 Physical Function Subscale

This is a subscale of the SF-36 Medical Outcomes Study. The Physical Function subscale assesses a self-reported ability to perform physical tasks. It is normalized for scores to range from 0 to 100 with a higher score indicating better function. (NCT00435188)
Timeframe: 12 month

Interventionunits on a scale (Mean)
Arm 169.9
Arm 262.7

Sf-36 Physical Function Subscale

This is a subscale of the SF-36 Medical Outcomes Study. The Physical Function subscale assesses a self-reported ability to perform physical tasks. It is normalized for scores to range from 0 to 100 with a higher score indicating better function. (NCT00435188)
Timeframe: 3 month

Interventionunits on a scale (Mean)
Arm 170
Arm 263.1

Sf-36 Physical Function Subscale

This is a subscale of the SF-36 Medical Outcomes Study. The Physical Function subscale assesses a self-reported ability to perform physical tasks. It is normalized for scores to range from 0 to 100 with a higher score indicating better function. (NCT00435188)
Timeframe: Baseline

Interventionunits on a scale (Mean)
Arm 168
Arm 262.9

Usual Gait Speed

(NCT00435188)
Timeframe: 12-month

Interventionmeters/second (Mean)
Arm 11.15
Arm 21.12

Usual Gait Speed

(NCT00435188)
Timeframe: 3 month

Interventionmeters/second (Mean)
Arm 11.09
Arm 21.07

Usual Gait Speed

Best of two trials over 8-foot walk (NCT00435188)
Timeframe: Baseline

Interventionmeters/second (Mean)
Arm 11.03
Arm 21.03

Self Rated Health

Self-report of overall health, reported as the number of participants reporting health as Excellent or Very good (NCT00435188)
Timeframe: 12 month

,
Interventionparticipants (Number)
Overall health is excellent or very goodOverall health is good, fair or poor
Arm 178100
Arm 270107

Self Rated Health

Self-report of overall health, reported as the number of participants reporting health as Excellent or Very good (NCT00435188)
Timeframe: 3 month

,
Interventionparticipants (Number)
Overall health is excellent or very goodOverall health is good, fair or poor
Arm 182102
Arm 275114

Self Rated Health

Self-report of overall health, reported as the number of participants reporting health as Excellent or Very good (NCT00435188)
Timeframe: Baseline

,
Interventionparticipants (Number)
Overall health is excellent or very goodOverall health is good, fair or poor
Arm 171128
Arm 276123

Change in Core Body Temperature, Baseline to 12 Months

(NCT00427193)
Timeframe: Baseline to 12 months

Interventiondegrees Celsius (Mean)
Caloric Restriction (CR)-0.05
Ad Libitum-0.03

Change in Core Temperature, Baseline to 24 Months

(NCT00427193)
Timeframe: Baseline to 24 months

Interventiondegrees Celsius (Mean)
Prescribed 25% Caloric Restriction-0.05
Ad Libitum-0.02

Change in Fat Mass

Difference in change in Fat Mass between prescribed 25% Caloric Restriction (CR) and Ad Libitum (AL) at 12 and 24 months as measured by dual X-ray absorptiometry (DXA) using the Hologic 4500A, Delphi W or Discovery A, by a standardized protocol according to a standardized protocol. Fat Mass (FM) was determined for the whole body. (NCT00427193)
Timeframe: baseline, 12 months

InterventionKg (Mean)
Prescribed 25% Caloric Restriction-6.1
Ad Libitum-0.3

Change in Fat Mass

Difference in change in Fat Mass between prescribed 25% Caloric Restriction (CR) and Ad Libitum (AL) at 12 and 24 months as measured by dual X-ray absorptiometry (DXA) using the Hologic 4500A, Delphi W or Discovery A, by a standardized protocol according to a standardized protocol. Fat Mass (FM) was determined for the whole body. (NCT00427193)
Timeframe: change 0 to 24 months

Interventionkg (Mean)
Prescribed 25% Caloric Restriction-6.1
Ad Libitum-0.2

Change in Resting Metabolic Rate (RMR) Corrected for Changes in Body Composition

(NCT00427193)
Timeframe: Baseline, 24 months

InterventionKcal/day (Mean)
Caloric Restriction (CR)-71
Ad Libitum-7

Change in Resting Metabolic Rate (RMR) Corrected for Changes in Body Composition, Baseline to 12 Months

(NCT00427193)
Timeframe: Baseline, 12 months

InterventionKcal/day (Mean)
Caloric Restriction (CR)-83
Ad Libitum-1

Change in Tumor Necrosis Factor-α (TNF-α), Baseline to 12 Months

(NCT00427193)
Timeframe: change baseline to 12 months

Interventionpg/mL (Mean)
Caloric Restriction (CR)-0.30
Ad Libitum-0.34

Reviews

1 review available for carnitine and Overweight

ArticleYear
The effects of L-carnitine supplementation on inflammatory and anti-inflammatory markers in adults: a systematic review and dose-response meta-analysis.
    Inflammopharmacology, 2023, Volume: 31, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Biomarkers; C-Reactive Protein; Carnitine; Dietary Su

2023

Trials

19 trials available for carnitine and Overweight

ArticleYear
Effects of gut microbiota and fatty acid metabolism on dyslipidemia following weight-loss diets in women: Results from a randomized controlled trial.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:11

    Topics: Adult; Caloric Restriction; Carnitine; Diet, Carbohydrate-Restricted; Diet, Reducing; Dyslipidemias;

2021
The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial.
    European journal of nutrition, 2022, Volume: 61, Issue:3

    Topics: Carnitine; Cholesterol, HDL; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin; Insu

2022
Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial.
    Clinical nutrition ESPEN, 2021, Volume: 46

    Topics: Cardiovascular Diseases; Carnitine; Dietary Supplements; Female; Humans; Iran; Liver; Obesity; Overw

2021
Effects of acupuncture on anthropometric and serum metabolic parameters in premenopausal overweight and obese women: a randomized, patient- and assessor-blind, sham-controlled clinical trial.
    Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2021, Volume: 39, Issue:1

    Topics: Acupuncture Therapy; Adult; Amino Acids; Anthropometry; Carnitine; Electroacupuncture; Female; Human

2021
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
    Gut, 2019, Volume: 68, Issue:2

    Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose

2019
Metabolomics identifies increases in the acylcarnitine profiles in the plasma of overweight subjects in response to mild weight loss: a randomized, controlled design study.
    Lipids in health and disease, 2018, Oct-15, Volume: 17, Issue:1

    Topics: Adult; Caloric Restriction; Carnitine; Fatty Acids, Nonesterified; Female; Humans; Intra-Abdominal F

2018
Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Biological trace element research, 2020, Volume: 193, Issue:2

    Topics: Adult; Body Weight; Carnitine; Chromium; Dietary Supplements; Double-Blind Method; Female; Gene Expr

2020
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
    Diabetes care, 2019, Volume: 42, Issue:8

    Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Re

2019
Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial.
    Scientific reports, 2015, May-19, Volume: 5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Blood Glucose; Carnitine; Cholesterol, HDL; Dietary Supplement

2015
L-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:8

    Topics: Ascorbic Acid; Benzothiazoles; Body Mass Index; Carnitine; Cholesterol, HDL; Cholesterol, LDL; Dieta

2015
Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
    Clinical endocrinology, 2016, Volume: 84, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Body Weights and Measures; Carnitine; Dietar

2016
Reduction in cardiometabolic risk factors by a multifunctional diet is mediated via several branches of metabolism as evidenced by nontargeted metabolite profiling approach.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:2

    Topics: Aged; Cardiovascular Diseases; Carnitine; Cholesterol, LDL; Diet; Fasting; Fatty Acids; Female; Huma

2017
Short-term effects of a green coffee extract-, Garcinia c ambogia- and L-carnitine-containing chewing gum on snack intake and appetite regulation.
    European journal of nutrition, 2018, Volume: 57, Issue:2

    Topics: Adult; Appetite Depressants; Appetite Regulation; Argentina; Body Mass Index; Carnitine; Chewing Gum

2018
Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals.
    Food & function, 2017, Jan-25, Volume: 8, Issue:1

    Topics: Adipose Tissue; Carnitine; Dietary Supplements; Double-Blind Method; Humans; Lactobacillus; Lactobac

2017
Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:2

    Topics: Adiposity; Adult; Aging; Amino Acids; Body Composition; Caloric Restriction; Carnitine; Cross-Sectio

2011
A combination of (ω-3) polyunsaturated fatty acids, polyphenols and L-carnitine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation in human peripheral blood mononuclear cells and HepG2 cells.
    Annals of nutrition & metabolism, 2011, Volume: 58, Issue:2

    Topics: Adult; Carnitine; Double-Blind Method; Fatty Acids; Fatty Acids, Omega-3; Female; Flavonoids; Functi

2011
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:2

    Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum

2012
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:2

    Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum

2012
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:2

    Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum

2012
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:2

    Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum

2012
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N

2012
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N

2012
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N

2012
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N

2012
Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months' consumption of a combination of bioactive food ingredients in overweight subjects.
    Endocrine, 2013, Volume: 44, Issue:2

    Topics: Adipokines; Adult; Alkaloids; Benzodioxoles; Capsaicin; Carnitine; Catechin; Diet, Reducing; Dietary

2013

Other Studies

13 other studies available for carnitine and Overweight

ArticleYear
Short communication: Circulating fatty acylcarnitines are elevated in overweight periparturient dairy cows in association with sphingolipid biomarkers of insulin resistance.
    Journal of dairy science, 2018, Volume: 101, Issue:1

    Topics: Animals; Biomarkers; Carnitine; Cattle; Cattle Diseases; Ceramides; Fatty Acids; Female; Insulin Res

2018
Plasma metabolomics reveals lower carnitine concentrations in overweight Labrador Retriever dogs.
    Acta veterinaria Scandinavica, 2019, Feb-26, Volume: 61, Issue:1

    Topics: Animals; Carnitine; Dogs; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Overweigh

2019
Indication of metabolic inflexibility to food intake in spontaneously overweight Labrador Retriever dogs.
    BMC veterinary research, 2019, Mar-20, Volume: 15, Issue:1

    Topics: Animals; Carnitine; Dog Diseases; Dogs; Eating; Lipid Metabolism; Male; Overweight; Phospholipids

2019
Lowered serum total L-carnitine levels are associated with obesity at term pregnancy.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:15

    Topics: Adult; Body Height; Body Mass Index; Carnitine; Dietary Supplements; Female; Fetal Weight; Gestation

2013
Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults.
    Omics : a journal of integrative biology, 2013, Volume: 17, Issue:12

    Topics: Aged; Amino Acids, Branched-Chain; Black or African American; Carnitine; Cross-Sectional Studies; Fe

2013
The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue.
    Scandinavian journal of medicine & science in sports, 2015, Volume: 25, Issue:1

    Topics: Adult; Carnitine; Exercise; Female; Humans; Male; Mitochondria; Mitochondria, Muscle; Muscle, Skelet

2015
Association between arterial stiffness and serum L-octanoylcarnitine and lactosylceramide in overweight middle-aged subjects: 3-year follow-up study.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adult; Antigens, CD; Blood Pressure; Body Mass Index; Carnitine; Case-Control Studies; Humans; Lacto

2015
Medium-chain dicarboxylic acylcarnitines as markers of n-3 PUFA-induced peroxisomal oxidation of fatty acids.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:8

    Topics: Animals; Biomarkers; Carnitine; Diet, High-Fat; Dietary Fats; Dietary Fats, Unsaturated; Fatty Acids

2015
Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status.
    Nutrients, 2016, May-27, Volume: 8, Issue:6

    Topics: Adult; Amino Acids; Body Mass Index; Cardiovascular Diseases; Carnitine; Cholesterol; Cholesterol, H

2016
Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women.
    Clinical nutrition (Edinburgh, Scotland), 2017, Volume: 36, Issue:5

    Topics: Adult; Aged; Blood Cells; Blood Glucose; Body Mass Index; Carnitine; Diabetes Mellitus, Type 2; Fema

2017
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
    Diabetes care, 2009, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Aged; Amino Acids; Blood Glucose; Carnitine; Cross-Sectional Studies; Fatty Acids

2009
Plasma acylcarnitines are associated with physical performance in elderly men.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2011, Volume: 66, Issue:5

    Topics: Aged; Carnitine; Gait; Hand Strength; Humans; Male; Mass Spectrometry; Motor Activity; Overweight

2011
Influence of dietary supplementation with (L)-carnitine on metabolic rate, fatty acid oxidation, body condition, and weight loss in overweight cats.
    American journal of veterinary research, 2012, Volume: 73, Issue:7

    Topics: Animals; Calorimetry, Indirect; Carnitine; Cat Diseases; Cats; Dietary Supplements; Energy Metabolis

2012