Page last updated: 2024-10-16

carnitine and Osteoarthritis, Knee

carnitine has been researched along with Osteoarthritis, Knee in 5 studies

Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Research Excerpts

ExcerptRelevanceReference
"L-carnitine displayed a protective effect against synovitis of KOA in vitro and in vivo experiments."8.31L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway. ( Ding, L; Liao, T; Mei, W; Wang, P; Yang, N; Zhang, L, 2023)
"L-carnitine displayed a protective effect against synovitis of KOA in vitro and in vivo experiments."4.31L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway. ( Ding, L; Liao, T; Mei, W; Wang, P; Yang, N; Zhang, L, 2023)
"Our data suggest three possible clinically actionable endotypes in primary OA: muscle weakness, arginine deficit and low inflammatory OA."4.02Endotypes of primary osteoarthritis identified by plasma metabolomics analysis. ( Furey, A; Liu, M; Rahman, P; Randell, EW; Sun, G; Werdyani, S; Zhai, G; Zhang, H, 2021)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Liao, T1
Mei, W1
Zhang, L2
Ding, L1
Yang, N1
Wang, P1
Werdyani, S1
Liu, M1
Zhang, H1
Sun, G1
Furey, A1
Randell, EW1
Rahman, P1
Zhai, G1
Baghban, F1
Hosseinzadeh, M1
Mozaffari-Khosravi, H1
Dehghan, A1
Fallahzadeh, H1
Tootsi, K1
Kals, J1
Zilmer, M1
Paapstel, K1
Ottas, A1
Märtson, A1
Malek Mahdavi, A1
Mahdavi, R1
Kolahi, S1
Zemestani, M1
Vatankhah, AM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Vitamin C Supplement Addiction vs. High-speed Spinal Manipulation to Routine Physiotherapy Treatment in Lateral Epicondylitis[NCT04445727]130 participants (Actual)Interventional2020-05-21Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for carnitine and Osteoarthritis, Knee

ArticleYear
The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.
    BMC musculoskeletal disorders, 2021, Feb-17, Volume: 22, Issue:1

    Topics: C-Reactive Protein; Carnitine; Dietary Supplements; Double-Blind Method; Female; Humans; Malondialde

2021
L-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis.
    Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:8

    Topics: Ascorbic Acid; Benzothiazoles; Body Mass Index; Carnitine; Cholesterol, HDL; Cholesterol, LDL; Dieta

2015

Other Studies

3 other studies available for carnitine and Osteoarthritis, Knee

ArticleYear
L-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway.
    Journal of orthopaedic surgery and research, 2023, May-26, Volume: 18, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Li

2023
Endotypes of primary osteoarthritis identified by plasma metabolomics analysis.
    Rheumatology (Oxford, England), 2021, 06-18, Volume: 60, Issue:6

    Topics: Aged; Arginine; Body Mass Index; Carnitine; Case-Control Studies; Coronary Disease; Diabetes Mellitu

2021
Medium- and long-chain acylcarnitines are associated with osteoarthritis severity and arterial stiffness in end-stage osteoarthritis patients: a case-control study.
    International journal of rheumatic diseases, 2018, Volume: 21, Issue:6

    Topics: Aged; Biomarkers; Carnitine; Case-Control Studies; Down-Regulation; Female; Humans; Male; Metabolomi

2018