carnitine has been researched along with Obesity in 162 studies
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current placebo-controlled double-blind randomized clinical trial was performed on 46 women with obesity, randomly allocated to either concomitant supplementation [L-carnitine tartrate (2 × 500 mg/day) + multistrain/multispecies synbiotic (1 capsule/day)] or monotherapy [L-carnitine tartrate (2 × 500 mg/day) + maltodextrin (1 capsule/day)] groups for 8 weeks." | 9.69 | Ameliorating effects of L-carnitine and synbiotic co-supplementation on anthropometric measures and cardiometabolic traits in women with obesity: a randomized controlled clinical trial. ( Fallah, F; Mahdavi, R, 2023) |
| "12-week L-carnitine supplementation in overweight or obese women with PCOS ameliorate insulin resistance, but has no effect on SHBG and lipid profile." | 9.51 | The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial. ( Fallahzadeh, H; Ghadiri-Anari, A; Hosseinzadeh, M; Nadjarzadeh, A; Pakravanfar, F; Sangouni, AA, 2022) |
| "The present study aimed to investigate the effect of l-carnitine supplementation on liver fat content and cardiometabolic outcomes in overweight/obese women with PCOS." | 9.41 | Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial. ( Ghadiri-Anari, A; Hosseinzadeh, M; Sangouni, AA; Sasanfar, B, 2021) |
| "Family history of obesity is the major predictor of obesity, and the metabolic abnormalities on amino acids, acylcarnitines, inflammation, insulin resistance, and NAFLD." | 9.27 | Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach. ( Caballero, AE; Duggirala, R; González-Chávez, A; Herrera-Rosas, A; Ibarra-González, I; León-Hernández, M; López-Alvarenga, JC; Mummidi, S; Romero-Ibarguengoitia, ME; Serratos-Canales, MF; Vadillo-Ortega, F, 2018) |
| "Acylcarnitines, fatty acid oxidation (FAO) intermediates, have been implicated in diet-induced insulin resistance and type 2 diabetes mellitus, as increased levels are found in obese insulin resistant humans." | 9.22 | Assessment of plasma acylcarnitines before and after weight loss in obese subjects. ( Ambler, GK; Hollak, CE; Houten, SM; Miller, SR; Murgatroyd, PR; Napolitano, A; Nunez, DJ; Schooneman, MG; Soeters, MR; Tan, CY; Vidal-Puig, A; Virtue, S, 2016) |
| "To determine fasting and insulin-stimulated levels of carnitine precursors, total and free carnitine, and acylcarnitines, and evaluate the impact of pioglitazone treatment in obese patients with polycystic ovary syndrome (PCOS)." | 9.16 | Free carnitine and acylcarnitines in obese patients with polycystic ovary syndrome and effects of pioglitazone treatment. ( Berge, RK; Bjørndal, B; Bohov, P; Gaster, M; Glintborg, D; Nygård, O; Seifert, R; Svardal, A; Vigerust, NF, 2012) |
| "To evaluate the effects of 1-year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and inflammatory parameters in obese type 2 diabetic patients." | 9.15 | Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2011) |
| "Our study wants to evaluate the effects of one year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and insulin resistance state in type 2 diabetic patients." | 9.14 | Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2010) |
| "L-Carnitine (L-C) transports fatty acids into mitochondria for oxidation and is marketed as a weight loss supplement." | 9.09 | L-Carnitine supplementation combined with aerobic training does not promote weight loss in moderately obese women. ( Gannon, J; Rich, PA; Self, M; Villani, RG, 2000) |
| "This study provides a systematic review and meta-analysis of randomized controlled trials, which have examined the effect of the carnitine on adult weight loss." | 8.93 | The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. ( Djafarian, K; Nouhi, M; Olyaeemanesh, A; Pooyandjoo, M; Shab-Bidar, S, 2016) |
| "Data on the functionalities of L-carnitine on obesity, diabetes, and as an ergogenic aid are summarized as follows: Obesity: Total lipid, triglyceride, and total protein increased during the 3T3-L1 cell differentiation." | 8.84 | Effects of L-carnitine on obesity, diabetes, and as an ergogenic aid. ( Cha, YS, 2008) |
| "Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis." | 8.12 | High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022) |
| "To address this gap, this study evaluated insulin sensitivity and subcellular localization of intramuscular triacylglycerol, diacylglycerol, and sphingolipids as well as muscle acylcarnitines and serum lipidomics in people with obesity." | 8.02 | Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. ( Bergman, BC; Broussard, JL; Brozinick, JT; Bui, HH; D'Alessandro, A; Harrison, K; Macias, E; Milligan, P; Nemkov, T; Newsom, SA; Perreault, L; Roth, KD, 2021) |
| "Acylcarnitines, intermediates of fatty acid oxidation, are known to be involved in obesity and insulin resistance." | 7.91 | Inter-generational link of obesity in term and preterm births: role of maternal plasma acylcarnitines. ( Bartell, TR; Cheng, TL; Clash, C; Hong, X; Hu, FB; Ji, Y; Liang, L; Pearson, C; Radovick, S; Sun, Q; Wang, G; Wang, X; Zhang, C; Zuckerman, B, 2019) |
| "L-Carnitine supplementation has been used to reduce obesity caused by high-fat diet, which is beneficial for lowering blood and hepatic lipid levels, and for ameliorating fatty liver." | 7.81 | L-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. ( Fu, Z; Guo, A; Kong, Y; Qi, Y; Shu, Q; Sun, S; Sun, Z; Wu, T, 2015) |
| "Insulin resistance may be linked to incomplete fatty acid β-oxidation and the subsequent increase in acylcarnitine species in different tissues including skeletal muscle." | 7.81 | Acylcarnitines: potential implications for skeletal muscle insulin resistance. ( Adams, SH; Aguer, C; Dent, R; Harper, ME; Hwang, DH; Knotts, TA; McCoin, CS; McPherson, R; Ono-Moore, K; Thrush, AB, 2015) |
| "We evaluate the effect of supplementation, at 300 mg kg(-1) body weight (BW), with the antioxidants α-lipoic acid (AL), betaine (BT), l-carnitine (LC), and the combination of these and exercise on obesity induced by a 9 week high-fat diet (HFD) in mice." | 7.80 | The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet. ( Jang, A; Jo, C; Jung, S; Kim, D; Kim, HJ; Sung, KS, 2014) |
| "The article investigates the impact of complex tools fosinopril, hepadyf and ezetimibe for correction of functional state of the endothelium and changes in blood pressure in patients with nonalcoholic steatohepatitis, obesity and essential hypertension stage II." | 7.80 | [The use of complex tools ezetimibe, hepadyfu fosinopril and correction of blood pressure and endothelial dysfunction in patients with nonalcoholic steatohepatitis and essential hypertension stage II]. ( Drozd, VIu; Haĭdychuk, VS; Khukhlina, OS; Kosar, LIu; Mandryk, OIe, 2014) |
| "The crucial role of L-carnitine in pregnancy metabolism suggests that nutritional supplementation of this amino acid can be offered to women who are either overweight or obese at the beginning of the pregnancy." | 7.79 | Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tipi-Akbas, P; Yilmazer, M, 2013) |
| "To develop a therapeutic agent for obesity-related metabolic disorders, a mixture of dietary components was prepared, including grape extract, green tea extract and l-carnitine (RGTC), and its effects on obesity, hyperlipidemia and non-alcoholic fatty liver disease examined." | 7.77 | A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, K; Lee, KH; Lee, WK; Ly, SY; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| "In the present study, we examined the effect of a mixture of dietary components, including red grape extract, soy isoflavone and L-carnitine (RISC), on obesity." | 7.77 | Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, HS; Lee, K; Lee, KH; Lee, WK; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| " We investigated the effect of dietary genistein (the principal soy isoflavone) alone and combined with L-carnitine to evaluate possible synergistic effects on the intentionally induced prediabetic state characterized by insulin resistance and obesity in C57Bl/6J mice fed a high-fat diet (HD)." | 7.73 | Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. ( Cha, YS; Lee, SJ; Park, HW; Yang, JY, 2006) |
| "Carnitine metabolism during starvation was studied in adult lean and obese female Zucker rats." | 7.67 | Carnitine metabolism in lean and obese Zucker rats during starvation. ( Albers, L; Brady, LJ; Brady, PS; Davis, AT; Hoppel, CL, 1986) |
| "Thus, adequate treatment for obesity is necessary, including lifestyle changes (diet adequation and physical activity) and pharmacotherapy." | 7.01 | L-carnitine and Acetyl-L Carnitine: A Possibility for Treating Alterations Induced by Obesity in the Central Nervous System. ( Abel, JDS; da Silva, LE; da Silva, MR; de Aguiar da Costa, M; de Oliveira, MP; Ludvig Gonçalves, C; Rezin, GT; Tartari, G, 2023) |
| "In light of the high prevalence of nonalcoholic fatty liver disease and obesity, treatment options for nonalcoholic steatohepatitis are of particular interest." | 5.91 | The efficacy of L-carnitine in patients with nonalcoholic steatohepatitis and concomitant obesity. ( Aringazina, R; Luo, C; Samusenkov, V; Zakharova, N, 2023) |
| "The current placebo-controlled double-blind randomized clinical trial was performed on 46 women with obesity, randomly allocated to either concomitant supplementation [L-carnitine tartrate (2 × 500 mg/day) + multistrain/multispecies synbiotic (1 capsule/day)] or monotherapy [L-carnitine tartrate (2 × 500 mg/day) + maltodextrin (1 capsule/day)] groups for 8 weeks." | 5.69 | Ameliorating effects of L-carnitine and synbiotic co-supplementation on anthropometric measures and cardiometabolic traits in women with obesity: a randomized controlled clinical trial. ( Fallah, F; Mahdavi, R, 2023) |
| "In women, tooth loss was associated with genotype TT vs." | 5.62 | Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men. ( Grube, M; Jedlitschky, G; Kocher, T; Meisel, P; Pagels, S; Völzke, H, 2021) |
| "Obesity is increasing rapidly across the globe." | 5.62 | Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats. ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
| "12-week L-carnitine supplementation in overweight or obese women with PCOS ameliorate insulin resistance, but has no effect on SHBG and lipid profile." | 5.51 | The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial. ( Fallahzadeh, H; Ghadiri-Anari, A; Hosseinzadeh, M; Nadjarzadeh, A; Pakravanfar, F; Sangouni, AA, 2022) |
| "This study examined the association of equol production with obesity and explored the mediating roles of equol-related gut microbiota and microbial carnitine metabolites." | 5.51 | Gut microbiota and acylcarnitine metabolites connect the beneficial association between equol and adiposity in adults: a prospective cohort study. ( Chen, D; Chen, YM; Fu, Y; Gou, W; Jiang, Z; Liu, CY; Wu, YY; Xie, K; Yan, Y; Yang, Y; Zheng, JS; Zhu, HL, 2022) |
| "Acylcarnitine analysis was performed by tandem mass spectrometry on dried-blood spots collected on day 3 of life." | 5.46 | Similarities between acylcarnitine profiles in large for gestational age newborns and obesity. ( Couce, ML; de Castro, MJ; López, M; Rite, S; Roca, I; Sánchez-Pintos, P, 2017) |
| "Eighty percent of cases had NAFLD with increase in chemerin as severity of NAFLD increased." | 5.43 | Serum Chemerin in Obese Children and Adolescents Before and After L-Carnitine Therapy: Relation to Nonalcoholic Fatty Liver Disease and Other Features of Metabolic Syndrome. ( Ebrahim, AO; Elkabbany, ZA; Hamed, AI; Hamza, RT; Shedid, AM, 2016) |
| "Obesity is associated with insulin resistance and impaired glucose tolerance, which represent characteristic features of the metabolic syndrome." | 5.43 | Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice. ( Bardova, K; Gardlo, A; Hansikova, J; Horakova, O; Kopecky, J; Kuda, O; Rombaldova, M; Rossmeisl, M, 2016) |
| "The present study aimed to investigate the effect of l-carnitine supplementation on liver fat content and cardiometabolic outcomes in overweight/obese women with PCOS." | 5.41 | Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial. ( Ghadiri-Anari, A; Hosseinzadeh, M; Sangouni, AA; Sasanfar, B, 2021) |
| "Our findings underscore the importance of changes in TMAO, choline and L-carnitine in improving insulin sensitivity during a weight-loss intervention for obese patients." | 5.30 | Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. ( Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D, 2019) |
| "To evaluate the reproductive and metabolic effects of L-carnitine plus metformin in clomiphene citrate (CC) resistant obese polycystic ovary syndrome (PCOS) women." | 5.30 | l-Carnitine plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effects: a randomized clinical trial. ( El Sharkwy, I; Sharaf El-Din, M, 2019) |
| " We examined associations of weight loss diet-induced changes in a gut microbiota-related metabolite trimethylamine N-oxide (TMAO), and its precursors (choline and l-carnitine), with changes in bone mineral density (BMD) considering diabetes-related factors." | 5.30 | Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T, 2019) |
| " We examined associations of 6-month changes in blood metabolites (TMAO, choline, and l-carnitine) with improvements in body weight (BW), waist circumference (WC), body fat composition, fat distribution, and resting energy expenditure (REE)." | 5.27 | Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Heianza, Y; Qi, L; Sacks, FM; Smith, SR; Sun, D, 2018) |
| "Family history of obesity is the major predictor of obesity, and the metabolic abnormalities on amino acids, acylcarnitines, inflammation, insulin resistance, and NAFLD." | 5.27 | Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach. ( Caballero, AE; Duggirala, R; González-Chávez, A; Herrera-Rosas, A; Ibarra-González, I; León-Hernández, M; López-Alvarenga, JC; Mummidi, S; Romero-Ibarguengoitia, ME; Serratos-Canales, MF; Vadillo-Ortega, F, 2018) |
| "Acylcarnitines, fatty acid oxidation (FAO) intermediates, have been implicated in diet-induced insulin resistance and type 2 diabetes mellitus, as increased levels are found in obese insulin resistant humans." | 5.22 | Assessment of plasma acylcarnitines before and after weight loss in obese subjects. ( Ambler, GK; Hollak, CE; Houten, SM; Miller, SR; Murgatroyd, PR; Napolitano, A; Nunez, DJ; Schooneman, MG; Soeters, MR; Tan, CY; Vidal-Puig, A; Virtue, S, 2016) |
| "To determine fasting and insulin-stimulated levels of carnitine precursors, total and free carnitine, and acylcarnitines, and evaluate the impact of pioglitazone treatment in obese patients with polycystic ovary syndrome (PCOS)." | 5.16 | Free carnitine and acylcarnitines in obese patients with polycystic ovary syndrome and effects of pioglitazone treatment. ( Berge, RK; Bjørndal, B; Bohov, P; Gaster, M; Glintborg, D; Nygård, O; Seifert, R; Svardal, A; Vigerust, NF, 2012) |
| "To evaluate the effects of 1-year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and inflammatory parameters in obese type 2 diabetic patients." | 5.15 | Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2011) |
| "Our study wants to evaluate the effects of one year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and insulin resistance state in type 2 diabetic patients." | 5.14 | Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2010) |
| "To determine the effects of a weight loss program, including dietary modifications, increased physical activity and dietary supplement (L-carnitine or placebo) on anthropometrics, leptin, insulin, the metabolic syndrome (MS) and insulin resistance in overweight /obese premenopausal women." | 5.11 | Weight loss favorably modifies anthropometrics and reverses the metabolic syndrome in premenopausal women. ( Brownbill, RA; Fernandez, ML; Herron, KL; Ilich, JZ; Koo, SI; Lofgren, IE; West, KL; Zern, TL, 2005) |
| "L-Carnitine (L-C) transports fatty acids into mitochondria for oxidation and is marketed as a weight loss supplement." | 5.09 | L-Carnitine supplementation combined with aerobic training does not promote weight loss in moderately obese women. ( Gannon, J; Rich, PA; Self, M; Villani, RG, 2000) |
| " The increase in plasma acylcarnitines during exercise is not influenced by type 2 diabetes or obesity." | 4.95 | Do diabetes and obesity affect the metabolic response to exercise? ( Plomgaard, P; Weigert, C, 2017) |
| " Evidence suggests that branched-chain amino acids, acylcarnitines and aromatic amino acids may play an early role on insulin resistance, exposing defects on amino acid metabolism, β-oxidation, and tricarboxylic acid cycle." | 4.93 | Metabolomics in diabetes, a review. ( Aguilar-Salinas, CA; Cruz-Bautista, I; Del Bosque-Plata, L; Pallares-Méndez, R, 2016) |
| "This study provides a systematic review and meta-analysis of randomized controlled trials, which have examined the effect of the carnitine on adult weight loss." | 4.93 | The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials. ( Djafarian, K; Nouhi, M; Olyaeemanesh, A; Pooyandjoo, M; Shab-Bidar, S, 2016) |
| "Branched-chain amino acids (BCAA), nonesterified fatty acids, organic acids, acylcarnitines, and phospholipids were identified as potential biomarkers for obesity." | 4.90 | Metabolomic biomarkers for obesity in humans: a short review. ( Hellmuth, C; Koletzko, B; Rauschert, S; Uhl, O, 2014) |
| "Data on the functionalities of L-carnitine on obesity, diabetes, and as an ergogenic aid are summarized as follows: Obesity: Total lipid, triglyceride, and total protein increased during the 3T3-L1 cell differentiation." | 4.84 | Effects of L-carnitine on obesity, diabetes, and as an ergogenic aid. ( Cha, YS, 2008) |
| "Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis." | 4.12 | High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022) |
| "We orally administered L-carnitine, which exerts protective effects on the mitochondria, to obesity-induced DN (db/db) mice for 8 weeks." | 4.12 | Effects of L-Carnitine Treatment on Kidney Mitochondria and Macrophages in Mice with Diabetic Nephropathy. ( Imakiire, T; Ishikiriyama, T; Ito, S; Kinoshita, M; Kumagai, H; Nakashima, H; Nakashima, M; Oshima, N; Seki, S; Yamagata, A, 2022) |
| " This study tested whether loss of weight by liraglutide combined with decreasing acylcarnitines (AcylCNs) represent an effective strategy to improve insulin sensitivity in obese insulin-resistant females." | 4.02 | Liraglutide treatment and acylcarnitine profiles in Egyptian obese insulin-resistant females. ( Ebied, SA; El-Kotishy, SM; Hussein, NA; Nour, HA; Salem, TM; Zaki, UK, 2021) |
| "To address this gap, this study evaluated insulin sensitivity and subcellular localization of intramuscular triacylglycerol, diacylglycerol, and sphingolipids as well as muscle acylcarnitines and serum lipidomics in people with obesity." | 4.02 | Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. ( Bergman, BC; Broussard, JL; Brozinick, JT; Bui, HH; D'Alessandro, A; Harrison, K; Macias, E; Milligan, P; Nemkov, T; Newsom, SA; Perreault, L; Roth, KD, 2021) |
| "Previous studies suggested the potential associations of trimethylamine N-oxide (TMAO) and its metabolic precursor l-carnitine with obesity." | 3.96 | Systematic investigation of the relationships of trimethylamine ( Gao, X; Randell, E; Sun, G; Tian, Y; Zhou, H, 2020) |
| "Acylcarnitines, intermediates of fatty acid oxidation, are known to be involved in obesity and insulin resistance." | 3.91 | Inter-generational link of obesity in term and preterm births: role of maternal plasma acylcarnitines. ( Bartell, TR; Cheng, TL; Clash, C; Hong, X; Hu, FB; Ji, Y; Liang, L; Pearson, C; Radovick, S; Sun, Q; Wang, G; Wang, X; Zhang, C; Zuckerman, B, 2019) |
| " IR in adults with obesity and diabetes is associated with changes in amino acid, free fatty acid (FFA), and mitochondrial acylcarnitine (AC) metabolism." | 3.91 | Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome. ( Bergman, BC; Carreau, AM; Cree-Green, M; Garcia-Reyes, Y; Nadeau, KJ; Pyle, L; Rahat, H, 2019) |
| "We conclude that the removal of dysfunctional mitochondria by induction of autophagy through PPARγ may be a novel mechanism by which carnitine improves insulin resistance and mitochondrial dysfunction in obesity." | 3.88 | Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction. ( Choi, JW; Chung, SS; Jang, HC; Jung, HS; Ohn, JH; Park, KS; Park, YJ, 2018) |
| "What is the central question of this study? Does improved metabolic health and insulin sensitivity following a weight-loss and fitness intervention in sedentary, obese women alter exercise-associated fuel metabolism and incomplete mitochondrial fatty acid oxidation (FAO), as tracked by blood acylcarnitine patterns? What is the main finding and its importance? Despite improved fitness and blood sugar control, indices of incomplete mitochondrial FAO increased in a similar manner in response to a fixed load acute exercise bout; this indicates that intramitochondrial muscle FAO is inherently inefficient and is tethered directly to ATP turnover." | 3.85 | Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons. ( Adams, SH; Burnett, DJ; Campbell, C; Casazza, GA; Chandler, CJ; Fernandez, JR; Fiehn, O; Garvey, WT; Harper, ME; Hoppel, CL; Hughen, RW; Hunter, GR; Keim, NL; Light, AR; Newman, JW; Souza, EC; Zhang, J, 2017) |
| " We hypothesized that increasing free carnitine levels by administration of the carnitine precursor γ-butyrobetaine (γBB) could facilitate FAO, thereby improving insulin sensitivity." | 3.83 | The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice. ( Hollak, CE; Houten, SM; Houtkooper, RH; Schooneman, MG; Soeters, MR; Vaz, FM; Wanders, RJ, 2016) |
| "Insulin resistance may be linked to incomplete fatty acid β-oxidation and the subsequent increase in acylcarnitine species in different tissues including skeletal muscle." | 3.81 | Acylcarnitines: potential implications for skeletal muscle insulin resistance. ( Adams, SH; Aguer, C; Dent, R; Harper, ME; Hwang, DH; Knotts, TA; McCoin, CS; McPherson, R; Ono-Moore, K; Thrush, AB, 2015) |
| "L-Carnitine supplementation has been used to reduce obesity caused by high-fat diet, which is beneficial for lowering blood and hepatic lipid levels, and for ameliorating fatty liver." | 3.81 | L-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. ( Fu, Z; Guo, A; Kong, Y; Qi, Y; Shu, Q; Sun, S; Sun, Z; Wu, T, 2015) |
| "This is the first study to hypothesize that L-carnitine deficiency participates in the pathogenesis of endometrial cancer by means of a mechanism which is unrelated with obesity and increased amount of fat in human body." | 3.81 | L-Carnitine: a new insight into the pathogenesis of endometrial cancer. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tuncer, N; Unlu, BS; Yilmazer, M, 2015) |
| "The article investigates the impact of complex tools fosinopril, hepadyf and ezetimibe for correction of functional state of the endothelium and changes in blood pressure in patients with nonalcoholic steatohepatitis, obesity and essential hypertension stage II." | 3.80 | [The use of complex tools ezetimibe, hepadyfu fosinopril and correction of blood pressure and endothelial dysfunction in patients with nonalcoholic steatohepatitis and essential hypertension stage II]. ( Drozd, VIu; Haĭdychuk, VS; Khukhlina, OS; Kosar, LIu; Mandryk, OIe, 2014) |
| "We evaluate the effect of supplementation, at 300 mg kg(-1) body weight (BW), with the antioxidants α-lipoic acid (AL), betaine (BT), l-carnitine (LC), and the combination of these and exercise on obesity induced by a 9 week high-fat diet (HFD) in mice." | 3.80 | The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet. ( Jang, A; Jo, C; Jung, S; Kim, D; Kim, HJ; Sung, KS, 2014) |
| "Overweight/obesity, malnutrition, and abnormalities in carnitine metabolism are recognized in kidney transplant recipients (KTRs)." | 3.80 | Nutritional status and carnitine level in kidney transplant recipients. ( Czajka, B; Dębska-Slizień, A; Małgorzewicz, S; Rutkowski, B, 2014) |
| "The crucial role of L-carnitine in pregnancy metabolism suggests that nutritional supplementation of this amino acid can be offered to women who are either overweight or obese at the beginning of the pregnancy." | 3.79 | Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. ( Arioz, DT; Kanat-Pektas, M; Koken, G; Koken, T; Tipi-Akbas, P; Yilmazer, M, 2013) |
| "In this study, we evaluated the effect of an analogue of l-carnitine on parameters involved with Metabolic Syndrome in obese Zucker rats." | 3.79 | Pharmacological evaluation of a β-hydroxyphosphonate analogue of l-carnitine in obese Zucker fa/fa rats. ( De la Cruz-Cordero, R; Duarte-Vázquez, MÁ; Mendoza-Rivera, B; Reyes-Esparza, J; Rodríguez-Fragoso, L; Rosado, JL; Solis, MG; Vite-Vallejo, O, 2013) |
| "Betaine (BET) reduces diet-induced liver lipid accumulation, and may relieve obesity-related metabolic disturbances." | 3.79 | Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. ( Auriola, S; Hanhineva, K; Huotari, A; Keski-Rahkonen, P; Kolehmainen, M; Lehtonen, M; Mykkänen, H; Olli, K; Pekkinen, J; Poutanen, K; Tiihonen, K, 2013) |
| "In the present study, we examined the effect of a mixture of dietary components, including red grape extract, soy isoflavone and L-carnitine (RISC), on obesity." | 3.77 | Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, HS; Lee, K; Lee, KH; Lee, WK; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| "To develop a therapeutic agent for obesity-related metabolic disorders, a mixture of dietary components was prepared, including grape extract, green tea extract and l-carnitine (RGTC), and its effects on obesity, hyperlipidemia and non-alcoholic fatty liver disease examined." | 3.77 | A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, K; Lee, KH; Lee, WK; Ly, SY; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| " We investigated the effect of dietary genistein (the principal soy isoflavone) alone and combined with L-carnitine to evaluate possible synergistic effects on the intentionally induced prediabetic state characterized by insulin resistance and obesity in C57Bl/6J mice fed a high-fat diet (HD)." | 3.73 | Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. ( Cha, YS; Lee, SJ; Park, HW; Yang, JY, 2006) |
| " Since the clinical utility of metformin in diabetes is probably traceable to inhibition of gluconeogenesis, its use as an adjunct to HCA/carnitine treatment of obesity in diabetics deserves evaluation, particularly as metformin therapy itself tends to reduce body weight." | 3.70 | Utility of metformin as an adjunct to hydroxycitrate/carnitine for reducing body fat in diabetics. ( McCarty, MF, 1998) |
| "To elucidate the relationship between carnitine metabolism and plasma ketone body concentrations in moderately obese patients with mild glucose intolerance, the ketone body and carnitine levels in the basal state were determined in 72 obese patients: 20 with normal glucose tolerance (NGT), 29 with impaired glucose tolerance (IGT), and 23 with non-insulin-dependent diabetes mellitus (NIDDM) having a fasting plasma glucose (FPG) level of less than 200 mg/dl." | 3.69 | Changes in carnitine metabolism with ketone body production in obese glucose-intolerant patients. ( Imamura, K; Inokuchi, T; Isogai, S; Nomoto, K; Nomura, K, 1995) |
| "Carnitine metabolism during starvation was studied in adult lean and obese female Zucker rats." | 3.67 | Carnitine metabolism in lean and obese Zucker rats during starvation. ( Albers, L; Brady, LJ; Brady, PS; Davis, AT; Hoppel, CL, 1986) |
| "Thus, adequate treatment for obesity is necessary, including lifestyle changes (diet adequation and physical activity) and pharmacotherapy." | 3.01 | L-carnitine and Acetyl-L Carnitine: A Possibility for Treating Alterations Induced by Obesity in the Central Nervous System. ( Abel, JDS; da Silva, LE; da Silva, MR; de Aguiar da Costa, M; de Oliveira, MP; Ludvig Gonçalves, C; Rezin, GT; Tartari, G, 2023) |
| "Obesity is an important worldwide public health problem and considered a disease of chronic low-grade inflammation." | 2.80 | Effect of L-carnitine supplementation in comparison with moderate aerobic training on serum inflammatory parameters in healthy obese women. ( Jafari, A; Karimi, M; Rafraf, M, 2015) |
| "Older age and obesity are associated with metabolic dysregulation; the mechanism by which these factors impact metabolism across the lifespan is important, but relatively unknown." | 2.53 | Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations. ( Bain, JR; Cohen, HJ; Huffman, KM; Kraus, VB; Kraus, WE; Morey, MC; Newgard, CB; Pieper, CF; Ravussin, E; Redman, LM; Stevens, RD; Thompson, DK, 2016) |
| "In light of the high prevalence of nonalcoholic fatty liver disease and obesity, treatment options for nonalcoholic steatohepatitis are of particular interest." | 1.91 | The efficacy of L-carnitine in patients with nonalcoholic steatohepatitis and concomitant obesity. ( Aringazina, R; Luo, C; Samusenkov, V; Zakharova, N, 2023) |
| "Obesity is a known risk factor for the development of gastroesophageal reflux disease (GERD), Barrett's Esophagus (BE) and the progression to esophageal adenocarcinoma." | 1.72 | Augmented CPT1A Expression Is Associated with Proliferation and Colony Formation during Barrett's Tumorigenesis. ( Altomare, DA; Andl, CD; Andl, T; Bernard, JN; Chinnaiyan, V; Le Bras, GF; Qureshi, MN, 2022) |
| "Obesity is increasing rapidly across the globe." | 1.62 | Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats. ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
| "L-carnitine (LC) has many beneficial effects on diabetic animals and humans, but its regulatory effect on chemerin as an inflammatory cytokine, and its receptor in diabetes status is unknown." | 1.62 | Novel Cardioprotective Effect of L-Carnitine on Obese Diabetic Mice: Regulation of Chemerin and CMKLRI Expression in Heart and Adipose Tissues. ( Amiri, R; Hosseini, SA; Tabandeh, MR, 2021) |
| "In participants with type 2 diabetes, after Bonferroni correction and rigorous adjustment, SDNN was inversely associated with higher levels of diacyl-phosphatidylcholine (PCaa) C32:0, PCaa C34:1, acyl-alkyl-phosphatidylcholine (PCae) C36:0, SM C16:0 and SM C16:1." | 1.62 | Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes. ( Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D, 2021) |
| "In women, tooth loss was associated with genotype TT vs." | 1.62 | Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men. ( Grube, M; Jedlitschky, G; Kocher, T; Meisel, P; Pagels, S; Völzke, H, 2021) |
| "Acylcarnitine analysis was performed by tandem mass spectrometry on dried-blood spots collected on day 3 of life." | 1.46 | Similarities between acylcarnitine profiles in large for gestational age newborns and obesity. ( Couce, ML; de Castro, MJ; López, M; Rite, S; Roca, I; Sánchez-Pintos, P, 2017) |
| "Maternal obesity is a global health problem that increases offspring obesity risk." | 1.46 | Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism. ( Baker, PR; Boyle, KE; Dabelea, D; De La Houssaye, BA; Friedman, JE; Patinkin, Z; Shapiro, AL; Vanderlinden, L; Woontner, M, 2017) |
| "Eighty percent of cases had NAFLD with increase in chemerin as severity of NAFLD increased." | 1.43 | Serum Chemerin in Obese Children and Adolescents Before and After L-Carnitine Therapy: Relation to Nonalcoholic Fatty Liver Disease and Other Features of Metabolic Syndrome. ( Ebrahim, AO; Elkabbany, ZA; Hamed, AI; Hamza, RT; Shedid, AM, 2016) |
| "Fasting insulin sensitivity was measured using homeostatic model assessment 2 (HOMA2), and adipose tissue was measured using dual-energy x-ray absorptiometry (DEXA)." | 1.43 | Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy. ( Culver, J; Jenkins, CA; Koethe, JR; Petucci, C; Shepherd, BE; Sterling, TR, 2016) |
| "Obesity is associated with insulin resistance and impaired glucose tolerance, which represent characteristic features of the metabolic syndrome." | 1.43 | Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice. ( Bardova, K; Gardlo, A; Hansikova, J; Horakova, O; Kopecky, J; Kuda, O; Rombaldova, M; Rossmeisl, M, 2016) |
| "Pioglitazone treatment restored in vivo muscle oxidative capacity in diabetic rats to the level of lean controls." | 1.42 | Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. ( Ciapaite, J; Houten, SM; Nicolay, K; Prompers, JJ; van den Broek, NM; Wessels, B, 2015) |
| "The purpose of this research was to describe the pharmacokinetic parameters of β-hydroxyphosphocarnitine (β-HPC; CAS No." | 1.40 | Pharmacokinetic and pharmacological effects of β-hydroxyphosphocarnitine in animal models. ( De la Cruz-Cordero, R; Duarte-Vázquez, MÁ; Mendoza-Rivera, B; Reyes-Esparza, J; Rodríguez-Fragoso, L; Rosado, JL, 2014) |
| "Amino acid concentrations were lower in type 2 diabetes compared with NW." | 1.38 | Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation. ( Arslanian, SA; Bacha, F; Chace, DH; de las Heras, J; DeJesus, VR; Lee, S; Michaliszyn, SF; Mihalik, SJ; Vockley, J, 2012) |
| "Obesity has reached epidemic proportions worldwide." | 1.38 | Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. ( Brauer, HA; Freemerman, AJ; Galanko, JA; Ilkayeva, OR; Kuan, PF; Makowski, L; Muehlbauer, MJ; Newgard, CB; O'Connell, TM; Sampey, BP; Stevens, RD; Troester, MA; Zhang, J, 2012) |
| "Insulin sensitivity was determined with the isoglycaemic-hyperinsulinaemic clamp technique." | 1.37 | Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes. ( Andersen, JL; Dela, F; Hansen, CN; Helge, JW; Hey-Mogensen, M; Larsen, S; Madsbad, S; Stride, N; Worm, D, 2011) |
| "Body weight gain was significantly higher in the H-SC group than in the H-SV group." | 1.36 | Stevia rebaudiana Bertoni extract supplementation improves lipid and carnitine profiles in C57BL/6J mice fed a high-fat diet. ( Cha, YS; Park, JE, 2010) |
| "Massive obesity is characterized by enhanced fatty acid turnover, insulin resistance, and often a fatty liver." | 1.29 | Increased liver carnitine content in obese women. ( Backman, L; Cederblad, G; Harper, P; Wadström, C, 1995) |
| " However, plasma levels of carnitine and the rate of urinary elimination of carnitine both after treatment and after an acute oral load were increased before and after surgery, indicating that carnitine was well absorbed by the shortened gut." | 1.27 | Oral L-carnitine administration after jejunoileal by-pass surgery. ( Burget, D; Cleator, I; Frohlich, J; Gourlay, RH; Hahn, P; Seccombe, D, 1984) |
| "Carnitine metabolism was studied in normal-weight and obese subjects by measurement of carnitine and its acyl derivatives in plasma and urine." | 1.26 | Carnitine metabolism in normal-weight and obese human subjects during fasting. ( Genuth, SM; Hoppel, CL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (9.26) | 18.7374 |
| 1990's | 4 (2.47) | 18.2507 |
| 2000's | 16 (9.88) | 29.6817 |
| 2010's | 95 (58.64) | 24.3611 |
| 2020's | 32 (19.75) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Y | 1 |
| Sun, Y | 1 |
| Sun, L | 1 |
| Liu, X | 1 |
| Zeng, R | 1 |
| Lin, X | 1 |
| Li, Y | 3 |
| Amiri, R | 1 |
| Tabandeh, MR | 1 |
| Hosseini, SA | 1 |
| Sangouni, AA | 2 |
| Pakravanfar, F | 1 |
| Ghadiri-Anari, A | 2 |
| Nadjarzadeh, A | 1 |
| Fallahzadeh, H | 2 |
| Hosseinzadeh, M | 3 |
| Sasanfar, B | 1 |
| Ruiz-Canela, M | 1 |
| Guasch-Ferré, M | 1 |
| Razquin, C | 1 |
| Toledo, E | 1 |
| Hernández-Alonso, P | 1 |
| Clish, CB | 1 |
| Li, J | 2 |
| Wittenbecher, C | 1 |
| Dennis, C | 1 |
| Alonso-Gómez, Á | 1 |
| Almanza-Aguilera, E | 1 |
| Liang, L | 2 |
| Corella, D | 1 |
| Gómez-Gracia, E | 1 |
| Estruch, R | 1 |
| Fiol, M | 1 |
| Lapetra, J | 1 |
| Serra-Majem, L | 1 |
| Ros, E | 1 |
| Arós, F | 1 |
| Salas-Salvadó, J | 1 |
| Hu, FB | 2 |
| Martínez-González, MÁ | 1 |
| Shipelin, VA | 2 |
| Trusov, NV | 1 |
| Apryatin, SA | 1 |
| Shumakova, AA | 2 |
| Timonin, AN | 1 |
| Riger, NA | 1 |
| Gmoshinski, IV | 2 |
| Nikityuk, DB | 1 |
| Terayama, Y | 1 |
| Nakamura, SI | 1 |
| Mekada, K | 1 |
| Matsuura, T | 1 |
| Ozaki, K | 1 |
| Adebayo, AS | 1 |
| Roman, M | 1 |
| Zakkar, M | 1 |
| Yusoff, S | 1 |
| Gulston, M | 1 |
| Joel-David, L | 1 |
| Anthony, B | 1 |
| Lai, FY | 1 |
| Murgia, A | 1 |
| Eagle-Hemming, B | 1 |
| Sheikh, S | 1 |
| Kumar, T | 1 |
| Aujla, H | 1 |
| Dott, W | 1 |
| Griffin, JL | 1 |
| Murphy, GJ | 1 |
| Woźniak, MJ | 1 |
| Ito, S | 1 |
| Nakashima, M | 1 |
| Ishikiriyama, T | 1 |
| Nakashima, H | 1 |
| Yamagata, A | 1 |
| Imakiire, T | 1 |
| Kinoshita, M | 1 |
| Seki, S | 1 |
| Kumagai, H | 1 |
| Oshima, N | 1 |
| Franco, AD | 1 |
| Morfino, P | 1 |
| Aimo, A | 1 |
| Vaughan, OR | 1 |
| Rosario, FJ | 1 |
| Chan, J | 1 |
| Cox, LA | 1 |
| Ferchaud-Roucher, V | 1 |
| Zemski-Berry, KA | 1 |
| Reusch, JEB | 1 |
| Keller, AC | 1 |
| Powell, TL | 1 |
| Jansson, T | 1 |
| Wu, YY | 1 |
| Gou, W | 1 |
| Yan, Y | 1 |
| Liu, CY | 1 |
| Yang, Y | 1 |
| Chen, D | 1 |
| Xie, K | 1 |
| Jiang, Z | 1 |
| Fu, Y | 1 |
| Zhu, HL | 1 |
| Zheng, JS | 1 |
| Chen, YM | 1 |
| Bernard, JN | 1 |
| Chinnaiyan, V | 1 |
| Andl, T | 1 |
| Le Bras, GF | 1 |
| Qureshi, MN | 1 |
| Altomare, DA | 1 |
| Andl, CD | 1 |
| Zakharova, N | 1 |
| Luo, C | 1 |
| Aringazina, R | 1 |
| Samusenkov, V | 1 |
| da Silva, LE | 1 |
| de Oliveira, MP | 1 |
| da Silva, MR | 1 |
| Abel, JDS | 1 |
| Tartari, G | 1 |
| de Aguiar da Costa, M | 1 |
| Ludvig Gonçalves, C | 1 |
| Rezin, GT | 1 |
| Fallah, F | 1 |
| Mahdavi, R | 2 |
| Lowry, JE | 1 |
| Tumurbaatar, B | 1 |
| D'Agostino, C | 1 |
| Main, E | 1 |
| Wright, TJ | 1 |
| Dillon, EL | 1 |
| Saito, TB | 1 |
| Porter, C | 1 |
| Andersen, CR | 1 |
| Brining, DL | 1 |
| Endsley, JJ | 1 |
| Sheffield-Moore, M | 1 |
| Volpi, E | 1 |
| Fang, R | 1 |
| Abate, N | 1 |
| Tuvdendorj, DR | 1 |
| Eyupoglu, ND | 1 |
| Caliskan Guzelce, E | 1 |
| Acikgoz, A | 1 |
| Uyanik, E | 1 |
| Bjørndal, B | 2 |
| Berge, RK | 3 |
| Svardal, A | 3 |
| Yildiz, BO | 1 |
| Niska-Blakie, J | 1 |
| Gopinathan, L | 1 |
| Low, KN | 1 |
| Kien, YL | 1 |
| Goh, CMF | 1 |
| Caldez, MJ | 1 |
| Pfeiffenberger, E | 1 |
| Jones, OS | 1 |
| Ong, CB | 1 |
| Kurochkin, IV | 1 |
| Coppola, V | 1 |
| Tessarollo, L | 1 |
| Choi, H | 1 |
| Kanagasundaram, Y | 1 |
| Eisenhaber, F | 1 |
| Maurer-Stroh, S | 1 |
| Kaldis, P | 1 |
| Yuan, J | 1 |
| Jiang, Q | 1 |
| Song, L | 1 |
| Liu, Y | 1 |
| Li, M | 1 |
| Lin, Q | 1 |
| Su, K | 1 |
| Ma, Z | 1 |
| Wang, Y | 1 |
| Liu, D | 1 |
| Dong, J | 1 |
| Kim, KW | 1 |
| Shin, WC | 1 |
| Choi, MS | 1 |
| Cho, JH | 1 |
| Park, HJ | 1 |
| Yoo, HH | 1 |
| Song, MY | 1 |
| Gao, X | 2 |
| Sun, G | 1 |
| Randell, E | 1 |
| Tian, Y | 1 |
| Zhou, H | 1 |
| Sawicka, AK | 1 |
| Renzi, G | 1 |
| Olek, RA | 1 |
| Meisel, P | 1 |
| Pagels, S | 1 |
| Grube, M | 1 |
| Jedlitschky, G | 1 |
| Völzke, H | 1 |
| Kocher, T | 1 |
| Ziegler, D | 1 |
| Strom, A | 1 |
| Straßburger, K | 1 |
| Knebel, B | 1 |
| Bönhof, GJ | 1 |
| Kotzka, J | 1 |
| Szendroedi, J | 1 |
| Roden, M | 1 |
| Hussein, NA | 1 |
| Ebied, SA | 1 |
| Nour, HA | 1 |
| Zaki, UK | 1 |
| El-Kotishy, SM | 1 |
| Salem, TM | 1 |
| Pereyra, AS | 1 |
| Rajan, A | 1 |
| Ferreira, CR | 1 |
| Ellis, JM | 1 |
| Armitage, EG | 1 |
| Barnes, A | 1 |
| Patrick, K | 1 |
| Bechar, J | 1 |
| Harrison, MJ | 1 |
| Lavery, GG | 1 |
| Rainger, GE | 1 |
| Buckley, CD | 1 |
| Loftus, NJ | 1 |
| Wilson, ID | 1 |
| Naylor, AJ | 1 |
| Baghban, F | 1 |
| Mozaffari-Khosravi, H | 1 |
| Dehghan, A | 1 |
| Leontyeva, EV | 1 |
| Broussard, JL | 1 |
| Perreault, L | 1 |
| Macias, E | 1 |
| Newsom, SA | 1 |
| Harrison, K | 1 |
| Bui, HH | 1 |
| Milligan, P | 1 |
| Roth, KD | 1 |
| Nemkov, T | 1 |
| D'Alessandro, A | 1 |
| Brozinick, JT | 1 |
| Bergman, BC | 2 |
| Taghavi, SA | 1 |
| van Wely, M | 1 |
| Jahanfar, S | 1 |
| Bazarganipour, F | 1 |
| Esmail, M | 1 |
| Anwar, S | 1 |
| Kandeil, M | 1 |
| El-Zanaty, AM | 1 |
| Abdel-Gabbar, M | 1 |
| Plomgaard, P | 1 |
| Weigert, C | 1 |
| Carayol, M | 1 |
| Leitzmann, MF | 1 |
| Ferrari, P | 1 |
| Zamora-Ros, R | 1 |
| Achaintre, D | 1 |
| Stepien, M | 1 |
| Schmidt, JA | 1 |
| Travis, RC | 1 |
| Overvad, K | 1 |
| Tjønneland, A | 1 |
| Hansen, L | 1 |
| Kaaks, R | 1 |
| Kühn, T | 1 |
| Boeing, H | 2 |
| Bachlechner, U | 2 |
| Trichopoulou, A | 1 |
| Bamia, C | 1 |
| Palli, D | 1 |
| Agnoli, C | 1 |
| Tumino, R | 1 |
| Vineis, P | 1 |
| Panico, S | 1 |
| Quirós, JR | 1 |
| Sánchez-Cantalejo, E | 1 |
| Huerta, JM | 1 |
| Ardanaz, E | 1 |
| Arriola, L | 1 |
| Agudo, A | 1 |
| Nilsson, J | 1 |
| Melander, O | 1 |
| Bueno-de-Mesquita, B | 1 |
| Peeters, PH | 1 |
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| Scalbert, A | 1 |
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| Baker, PR | 2 |
| Patinkin, Z | 1 |
| Shapiro, AL | 1 |
| De La Houssaye, BA | 1 |
| Woontner, M | 1 |
| Boyle, KE | 3 |
| Vanderlinden, L | 1 |
| Dabelea, D | 1 |
| Friedman, JE | 2 |
| Sánchez-Pintos, P | 1 |
| de Castro, MJ | 1 |
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| Heianza, Y | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Low-Carbohydrate or Restricted-Calories Diet on Body Weight[NCT01358890] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2011-05-31 | Completed | ||
| An Observational Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery[NCT02908009] | 80 participants (Anticipated) | Observational | 2016-09-09 | Recruiting | |||
| Effects of Acupuncture on Serum Metabolic Parameters in Pre-menopausal Obese Women: A Randomized Controlled Trial[NCT02066090] | 120 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)[NCT00072995] | 811 participants | Interventional | 2003-09-30 | Completed | |||
| Longitudinal Profiling of Gut Microbiome in Overweight or Obese Participants on a Modified Atkins Diet: a Prospective Cohort Study[NCT04207879] | 75 participants (Actual) | Observational | 2020-01-01 | Active, not recruiting | |||
| Pilot Study Aimed to Determine the Optimal Design for the UCLA/Danone Probiotic Intervention Study Related to Stress[NCT05026333] | 100 participants (Actual) | Interventional | 2021-06-25 | Completed | |||
| Childhood Obesity - Programming by Infant Nutrition[NCT00338689] | 1,678 participants (Actual) | Interventional | 2002-10-31 | Active, not recruiting | |||
| Efficacy of Vitamin C Supplement Addiction vs. High-speed Spinal Manipulation to Routine Physiotherapy Treatment in Lateral Epicondylitis[NCT04445727] | 130 participants (Actual) | Interventional | 2020-05-21 | Enrolling by invitation | |||
| An Observational Cohort Study of Adipose Tissue and Immune Activation in Treated HIV Infection[NCT04439448] | 100 participants (Actual) | Observational | 2013-04-12 | Completed | |||
| Exercise-mediated Rescue of Mitochondrial Derangements Driving Insulin Resistance in Humans (EX-MITO-DYS-IR)[NCT06080594] | 15 participants (Anticipated) | Interventional | 2024-02-29 | Recruiting | |||
| Mitochondrial Derangements Driving Muscle Insulin Resistance in Humans[NCT06080581] | 30 participants (Anticipated) | Observational | 2023-10-20 | Recruiting | |||
| Bioenergetics and Metabolism in Pediatric Populations[NCT03323294] | 175 participants (Anticipated) | Observational | 2017-10-18 | Active, not recruiting | |||
| Effects of Almond Consumption on Cardiovascular, Metabolomic, and Microbiome Profiles in Millennials: Implications of Systemic Glucoregulatory Mechanisms[NCT03084003] | 74 participants (Actual) | Interventional | 2016-02-18 | Completed | |||
| LIFESTAT - Living With Statins, a Cross Sectional Study on the Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being[NCT02250677] | 75 participants (Actual) | Observational | 2014-04-30 | Completed | |||
| Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being[NCT02796378] | Phase 4 | 30 participants (Anticipated) | Interventional | 2016-06-30 | Active, not recruiting | ||
| Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being[NCT02255682] | Phase 4 | 35 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Evidence-Based Approach to Dietary Management of Prader-Willi Syndrome (PWS)[NCT02011360] | 10 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| Metabolic Impact of Dietary Protein Supplementation in Surgical Weight Loss II (MIPS II)[NCT02269410] | 6 participants (Actual) | Interventional | 2014-11-30 | Completed | |||
| Pilot Study to Test Dietary Fat Delivery[NCT02101996] | 9 participants (Actual) | Observational | 2014-06-30 | Completed | |||
| Effect of Dietary Macronutrient Composition on Liver Substrate Metabolism[NCT01371396] | 24 participants (Actual) | Interventional | 2007-09-01 | Completed | |||
| Identification of Metabolic Phenotypes in Childhood Obesity by 1H-NMR Metabolomics of Blood Plasma[NCT03014856] | 102 participants (Actual) | Observational | 2012-05-31 | Completed | |||
| The Effect of PPARgamma Stimulation on Glucose Metabolism, Insulin Resistance, Growth Hormone and Cortisol on Women Suffering From Polycystic Ovary Syndrome[NCT00145340] | Phase 4 | 30 participants | Interventional | 2002-09-30 | Completed | ||
| Correlation Between Carnitine Deficiency and Hypoglycemic Events in Type I Diabetes; Effects of Carnitine Supplementation on Hypoglycemic Events in Type I Diabetes[NCT00351234] | 200 participants (Actual) | Observational | 2004-10-31 | Completed | |||
| Effect of the Administration of L-Carnitine on Body Fat Percentage and Body Weight in Overweight Women in Crossfit Training.[NCT03436277] | Phase 2 | 24 participants (Anticipated) | Interventional | 2018-12-17 | Not yet recruiting | ||
| Resistance Training Modulation of Fat Metabolism in Obese Postmenopausal Women[NCT05351476] | 120 participants (Anticipated) | Interventional | 2022-05-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for carnitine and Obesity
| Article | Year |
|---|---|
L-carnitine and Acetyl-L Carnitine: A Possibility for Treating Alterations Induced by Obesity in the Central Nervous System.
Topics: Acetylcarnitine; Carnitine; Central Nervous System; Humans; Obesity; Oxidative Stress | 2023 |
The bright and the dark sides of L-carnitine supplementation: a systematic review.
Topics: Age Factors; Body Composition; Carnitine; Cognition; Dietary Carbohydrates; Dietary Supplements; Ene | 2020 |
Pharmacological and non-pharmacological strategies for obese women with subfertility.
Topics: Abortion, Spontaneous; Appetite Depressants; Bias; Carnitine; Clomiphene; Dexfenfluramine; Drug Ther | 2021 |
Do diabetes and obesity affect the metabolic response to exercise?
Topics: AMP-Activated Protein Kinases; Blood Glucose; Carnitine; Diabetes Mellitus, Type 2; Exercise; Fatty | 2017 |
Metabolomic biomarkers for obesity in humans: a short review.
Topics: Amino Acids, Branched-Chain; Biomarkers; Carnitine; Case-Control Studies; Cross-Sectional Studies; H | 2014 |
Liver Cirrhosis: Evaluation, Nutritional Status, and Prognosis.
Topics: Carcinoma, Hepatocellular; Carnitine; Electric Impedance; Fibrosis; Hand Strength; Hepatitis C, Chro | 2015 |
Metabolomics in diabetes, a review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Humans; Insu | 2016 |
Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.
Topics: Aged; Aging; Amino Acids; Body Mass Index; Carnitine; Female; Humans; Male; Metabolomics; Obesity; P | 2016 |
The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials.
Topics: Carnitine; Dietary Supplements; Fatty Acids; Humans; Obesity; Randomized Controlled Trials as Topic; | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Fatty Acid Oxidation and Its Relation with Insulin Resistance and Associated Disorders.
Topics: Animals; Carnitine; Carnitine Acyltransferases; Deficiency Diseases; Diabetes Mellitus; Diet, High-F | 2016 |
Effects of L-carnitine on obesity, diabetes, and as an ergogenic aid.
Topics: 3T3-L1 Cells; Animals; Carnitine; Cell Differentiation; Diabetes Mellitus, Type 2; Exercise; Humans; | 2008 |
Dietary fat intake, supplements, and weight loss.
Topics: Animals; Anti-Obesity Agents; Aspirin; Carnitine; Citrates; Dietary Fats; Dietary Supplements; Ephed | 2000 |
Nutrition and the heart.
Topics: Animals; Cachexia; Carnitine; Cat Diseases; Cats; Diet; Dog Diseases; Dogs; Heart Diseases; Heart Fa | 1989 |
Regulation of the mammalian pyruvate dehydrogenase complex by covalent modification.
Topics: Adenosine Triphosphate; Adipose Tissue; Animals; Brain; Calcium; Carnitine; DNA; Enzyme Activation; | 1973 |
30 trials available for carnitine and Obesity
| Article | Year |
|---|---|
Effects of gut microbiota and fatty acid metabolism on dyslipidemia following weight-loss diets in women: Results from a randomized controlled trial.
Topics: Adult; Caloric Restriction; Carnitine; Diet, Carbohydrate-Restricted; Diet, Reducing; Dyslipidemias; | 2021 |
The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial.
Topics: Carnitine; Cholesterol, HDL; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin; Insu | 2022 |
Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial.
Topics: Cardiovascular Diseases; Carnitine; Dietary Supplements; Female; Humans; Iran; Liver; Obesity; Overw | 2021 |
Plasma acylcarnitines and risk of incident heart failure and atrial fibrillation: the Prevención con dieta mediterránea study.
Topics: Atrial Fibrillation; Cardiovascular Diseases; Carnitine; Diabetes Mellitus, Type 2; Diet, Mediterran | 2022 |
Gut microbiota and acylcarnitine metabolites connect the beneficial association between equol and adiposity in adults: a prospective cohort study.
Topics: Adiposity; Adult; Carnitine; Equol; Female; Gastrointestinal Microbiome; Humans; Isoflavones; Male; | 2022 |
Ameliorating effects of L-carnitine and synbiotic co-supplementation on anthropometric measures and cardiometabolic traits in women with obesity: a randomized controlled clinical trial.
Topics: Blood Glucose; Cardiovascular Diseases; Carnitine; Female; Humans; Iran; Lipids; Obesity; Synbiotics | 2023 |
Effects of acupuncture on anthropometric and serum metabolic parameters in premenopausal overweight and obese women: a randomized, patient- and assessor-blind, sham-controlled clinical trial.
Topics: Acupuncture Therapy; Adult; Amino Acids; Anthropometry; Carnitine; Electroacupuncture; Female; Human | 2021 |
The effect of L-Carnitine supplementation on clinical symptoms, C-reactive protein and malondialdehyde in obese women with knee osteoarthritis: a double blind randomized controlled trial.
Topics: C-Reactive Protein; Carnitine; Dietary Supplements; Double-Blind Method; Female; Humans; Malondialde | 2021 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial.
Topics: Adipose Tissue, White; Adiposity; Adult; Body Weight; Caloric Restriction; Carnitine; Choline; Diabe | 2018 |
Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach.
Topics: Adolescent; Adult; Amino Acids; Carnitine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Femal | 2018 |
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose | 2019 |
Changes in Plasma Acylcarnitine and Lysophosphatidylcholine Levels Following a High-Fructose Diet: A Targeted Metabolomics Study in Healthy Women.
Topics: Adult; Biomarkers; Carnitine; Cross-Over Studies; Diet, Carbohydrate-Restricted; Dietary Sugars; Fem | 2018 |
Effects of a topical lotion containing aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola on thigh circumference, skinfold thickness, and fat mass in sedentary females.
Topics: Adiposity; Administration, Cutaneous; Adolescent; Adult; Aminophylline; Caffeine; Carnitine; Centell | 2019 |
l-Carnitine plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effects: a randomized clinical trial.
Topics: Adult; Blood Glucose; Carnitine; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Horm | 2019 |
Effects of Chromium and Carnitine Co-supplementation on Body Weight and Metabolic Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adult; Body Weight; Carnitine; Chromium; Dietary Supplements; Double-Blind Method; Female; Gene Expr | 2020 |
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Re | 2019 |
Acute effect on satiety, resting energy expenditure, respiratory quotient, glucagon-like peptide-1, free fatty acids, and glycerol following consumption of a combination of bioactive food ingredients in overweight subjects.
Topics: Adult; Alkaloids; Area Under Curve; Basal Metabolism; Benzodioxoles; Capsaicin; Carnitine; Catechin; | 2013 |
Dietary protein intake affects amino acid and acylcarnitine metabolism in infants aged 6 months.
Topics: Amino Acids; Body Weight; Breast Feeding; Carnitine; Dietary Proteins; Double-Blind Method; Female; | 2015 |
Effect of L-carnitine supplementation in comparison with moderate aerobic training on serum inflammatory parameters in healthy obese women.
Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Carnitine; Dietary Supplements; Double-Blind | 2015 |
L-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritis.
Topics: Ascorbic Acid; Benzothiazoles; Body Mass Index; Carnitine; Cholesterol, HDL; Cholesterol, LDL; Dieta | 2015 |
Assessment of plasma acylcarnitines before and after weight loss in obese subjects.
Topics: Adult; Anthropometry; Body Composition; Carnitine; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Aci | 2016 |
[The supplementation of L-carnitine does not promote alterations in the resting metabolic rate and in the use of energetic substrates in physically active individuals].
Topics: Adult; Analysis of Variance; Basal Metabolism; Carnitine; Exercise; Fatty Acids; Female; Humans; Mal | 2010 |
Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients.
Topics: Anti-Obesity Agents; Body Weight; Carnitine; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy | 2010 |
Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients.
Topics: Adiponectin; Anti-Inflammatory Agents; Anti-Obesity Agents; Blood Glucose; Body Mass Index; Body Wei | 2011 |
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.
Topics: Adult; Amino Acids, Branched-Chain; Carnitine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Ga | 2011 |
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.
Topics: Adult; Amino Acids, Branched-Chain; Carnitine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Ga | 2011 |
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.
Topics: Adult; Amino Acids, Branched-Chain; Carnitine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Ga | 2011 |
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.
Topics: Adult; Amino Acids, Branched-Chain; Carnitine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Ga | 2011 |
Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, In vitro, ex vivo and in vivo studies.
Topics: Adipose Tissue; Administration, Cutaneous; Adult; Caffeine; Carnitine; Colforsin; Cosmetics; Dermis; | 2011 |
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum | 2012 |
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum | 2012 |
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum | 2012 |
Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity.
Topics: Adult; Aged; Biological Transport; Biomarkers; Body Composition; Carnitine; Fatty Acids; Female; Hum | 2012 |
Free carnitine and acylcarnitines in obese patients with polycystic ovary syndrome and effects of pioglitazone treatment.
Topics: Adult; Carnitine; Female; Humans; Hypoglycemic Agents; Obesity; Pioglitazone; Polycystic Ovary Syndr | 2012 |
Weight loss favorably modifies anthropometrics and reverses the metabolic syndrome in premenopausal women.
Topics: Adult; Anthropometry; Body Composition; Carnitine; Diet, Reducing; Dietary Proteins; Dietary Supplem | 2005 |
L-Carnitine supplementation combined with aerobic training does not promote weight loss in moderately obese women.
Topics: Adipose Tissue; Adult; Analysis of Variance; Basal Metabolism; Body Composition; Carnitine; Double-B | 2000 |
117 other studies available for carnitine and Obesity
| Article | Year |
|---|---|
Novel Cardioprotective Effect of L-Carnitine on Obese Diabetic Mice: Regulation of Chemerin and CMKLRI Expression in Heart and Adipose Tissues.
Topics: Animals; Carnitine; Chemokines; Diabetes Mellitus, Experimental; Intercellular Signaling Peptides an | 2021 |
Comprehensive assessment of the effectiveness of l-carnitine and transresveratrol in rats with diet-induced obesity.
Topics: Animals; Carnitine; Diet, High-Fat; Male; Obesity; Rats; Rats, Wistar; Resveratrol | 2022 |
High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models.
Topics: Alloxan; Animals; Carcinogenesis; Carnitine; Diet, High-Fat; Disease Models, Animal; Glucose Intoler | 2022 |
Gene and metabolite expression dependence on body mass index in human myocardium.
Topics: Aged; Aged, 80 and over; Body Mass Index; Carnitine; Case-Control Studies; Cholesterol; Cohort Studi | 2022 |
Effects of L-Carnitine Treatment on Kidney Mitochondria and Macrophages in Mice with Diabetic Nephropathy.
Topics: Animals; Carnitine; Diabetes Mellitus; Diabetic Nephropathies; DNA, Mitochondrial; Kidney; Macrophag | 2022 |
Plasma acylcarnitine, risk for heart failure or atrial fibrillation, and effects of the Mediterranean diet or obesity.
Topics: Atrial Fibrillation; Carnitine; Diet, Mediterranean; Heart Failure; Humans; Obesity | 2022 |
Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in mice.
Topics: Adult Children; Animals; Cardiomegaly; Cardiovascular Diseases; Carnitine; Female; Fetal Heart; Hear | 2022 |
Augmented CPT1A Expression Is Associated with Proliferation and Colony Formation during Barrett's Tumorigenesis.
Topics: Adenocarcinoma; Animals; Barrett Esophagus; Carcinogenesis; Carnitine; Carnitine O-Palmitoyltransfer | 2022 |
The efficacy of L-carnitine in patients with nonalcoholic steatohepatitis and concomitant obesity.
Topics: Carnitine; Diet, Reducing; Humans; Non-alcoholic Fatty Liver Disease; Obesity | 2023 |
Effect of high-fat diet on peripheral blood mononuclear cells and adipose tissue in early stages of diet-induced weight gain.
Topics: Animals; Autophagy; Carnitine; Diet, High-Fat; Homeostasis; Inflammation; Insulin; Insulin Resistanc | 2019 |
Circulating gut microbiota metabolite trimethylamine N-oxide and oral contraceptive use in polycystic ovary syndrome.
Topics: Adolescent; Adult; Betaine; Blood Glucose; Cardiovascular Diseases; Carnitine; Choline; Female; Gast | 2019 |
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplem | 2020 |
L-Carnitine Is Involved in Hyperbaric Oxygen-Mediated Therapeutic Effects in High Fat Diet-Induced Lipid Metabolism Dysfunction.
Topics: Adipose Tissue; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Chromatography, Liquid; Diet, | 2020 |
Systematic investigation of the relationships of trimethylamine
Topics: Adipocytes; Adipose Tissue, White; Adult; Animals; Body Composition; Body Weight; Carnitine; Diet, H | 2020 |
Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men.
Topics: Adiposity; Adult; Aged; Aged, 80 and over; Carnitine; Female; Follow-Up Studies; Genetic Predisposit | 2021 |
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, T | 2021 |
Liraglutide treatment and acylcarnitine profiles in Egyptian obese insulin-resistant females.
Topics: Adult; Anti-Obesity Agents; Biomarkers; Blood Glucose; Carnitine; Case-Control Studies; Egypt; Femal | 2021 |
Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Female; Humans; Insulin Resistance; Mice; Obes | 2020 |
Metabolic consequences for mice lacking Endosialin: LC-MS/MS-based metabolic phenotyping of serum from C56Bl/6J Control and CD248 knock-out mice.
Topics: Adipose Tissue; Animals; Antigens, CD; Antigens, Neoplasm; Carnitine; Cholesterol; Chromatography, H | 2021 |
Effect of Resveratrol, L-Carnitine, and Aromatic Amino Acid Supplements on the Trace Element Content in the Organs of Mice with Dietary-Induced Obesity.
Topics: Amino Acids, Aromatic; Animals; Carnitine; Diet, High-Fat; Dietary Supplements; Mice; Mice, Inbred D | 2022 |
Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution.
Topics: Adult; Carnitine; Citric Acid Cycle; Cohort Studies; Female; Glucose Clamp Technique; Glucose Tolera | 2021 |
Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats.
Topics: Animals; Anti-Obesity Agents; Atherosclerosis; Atorvastatin; Blood Glucose; Body Weight; Carnitine; | 2021 |
Blood Metabolic Signatures of Body Mass Index: A Targeted Metabolomics Study in the EPIC Cohort.
Topics: Adult; Amino Acids; Bile Duct Neoplasms; Biogenic Amines; Blood Proteins; Body Mass Index; Carcinoma | 2017 |
Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction.
Topics: Animals; Autophagosomes; Autophagy; Carnitine; Diet, High-Fat; Glucose Intolerance; Insulin; Insulin | 2018 |
Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism.
Topics: Adiposity; Amino Acids; Biomarkers; Carnitine; Colorado; Electron Transport; Energy Metabolism; Fatt | 2017 |
Similarities between acylcarnitine profiles in large for gestational age newborns and obesity.
Topics: Cardiomyopathies; Carnitine; Female; Gestational Age; Humans; Hyperammonemia; Infant, Newborn; Infan | 2017 |
Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
Topics: Animals; Carnitine; Diet, High-Fat; Energy Metabolism; Face; Fatty Acids; Female; Gene Expression Re | 2018 |
CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity.
Topics: Adult; Aged; Animals; Carcinoma, Hepatocellular; Carnitine; Carnitine O-Palmitoyltransferase; Case-C | 2018 |
Obesity-Related Metabolomic Profiles and Discrimination of Metabolically Unhealthy Obesity.
Topics: Adolescent; Adult; Carnitine; Case-Control Studies; Humans; Iran; Lysophosphatidylcholines; Metabolo | 2018 |
Acylcarnitine Profiles in Plasma and Tissues of Hyperglycemic NZO Mice Correlate with Metabolite Changes of Human Diabetes.
Topics: Adipose Tissue; Animals; Blood Glucose; Carnitine; Fatty Acids, Nonesterified; Female; Hyperglycemia | 2018 |
Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome.
Topics: Absorptiometry, Photon; Adipose Tissue; Adolescent; Amino Acids; Blood Glucose; Body Composition; Ca | 2019 |
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Topics: Acetylation; Acyl-CoA Dehydrogenase, Long-Chain; Animals; Berberine; Carnitine; Diet, High-Fat; Drug | 2019 |
Effectiveness of Local Fat-Dissolving Solution Injection.
Topics: Adipose Tissue; Adult; Aminophylline; Ascorbic Acid; Body Mass Index; Carnitine; Cheek; Drug Combina | 2019 |
Plasma metabolomic profiling of amino acids and polar lipids in Iranian obese adults.
Topics: Adult; Alcohol Drinking; Amino Acids; Biomarkers; Body Mass Index; Carnitine; Case-Control Studies; | 2019 |
The Impact of OMEGA-3 Fatty Acids Supplementation on Insulin Resistance and Content of Adipocytokines and Biologically Active Lipids in Adipose Tissue of High-Fat Diet Fed Rats.
Topics: Adiponectin; Adipose Tissue; Animals; Blood Glucose; Carnitine; Carnitine O-Palmitoyltransferase; Ce | 2019 |
American Ginseng and Asian Ginseng Intervention in Diet-Induced Obese Mice: Metabolomics Reveals Distinct Metabolic Profiles.
Topics: Animals; Carnitine; Chromatography, Liquid; Cysteine; Diet, High-Fat; Fatty Acids; Glucose; Linoleic | 2019 |
Inter-generational link of obesity in term and preterm births: role of maternal plasma acylcarnitines.
Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Boston; Carnitine; Child; Child, Preschool; Female; | 2019 |
Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.
Topics: Adult; Aged; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Cross-Sectional Studies; | 2019 |
Leucine and protein metabolism in obese Zucker rats.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adipose Tissue; Amino Acids, Branched-Chain; Anim | 2013 |
Lowered serum total L-carnitine levels are associated with obesity at term pregnancy.
Topics: Adult; Body Height; Body Mass Index; Carnitine; Dietary Supplements; Female; Fetal Weight; Gestation | 2013 |
Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach.
Topics: Acetylcarnitine; Adipose Tissue; Adiposity; Animals; Betaine; Blood Glucose; Carnitine; Chromatograp | 2013 |
Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload.
Topics: Animals; Carnitine; Fatty Acids; Female; Kinetics; Liver; Metabolic Networks and Pathways; Mitochond | 2013 |
Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults.
Topics: Aged; Amino Acids, Branched-Chain; Black or African American; Carnitine; Cross-Sectional Studies; Fe | 2013 |
Obesity and lipid stress inhibit carnitine acetyltransferase activity.
Topics: Acetyl Coenzyme A; Animals; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransfera | 2014 |
The molecular and metabolic influence of long term agmatine consumption.
Topics: Agmatine; Animals; Biological Transport, Active; Carnitine; Cyclic AMP; Dietary Fats; Fatty Acids; G | 2014 |
Linking diet, physical activity, cardiorespiratory fitness and obesity to serum metabolite networks: findings from a population-based study.
Topics: Amino Acids; Biomarkers; Body Mass Index; Carbohydrates; Carnitine; Coffee; Diet; Energy Metabolism; | 2014 |
Supplemental carnitine affects the microRNA expression profile in skeletal muscle of obese Zucker rats.
Topics: Animals; Carnitine; Cluster Analysis; Computational Biology; Dietary Supplements; Gene Expression Pr | 2014 |
The effect of dietary α-lipoic acid, betaine, l-carnitine, and swimming on the obesity of mice induced by a high-fat diet.
Topics: Adipocytes; Animals; Antioxidants; Betaine; Blood Glucose; Body Weight; Carnitine; Cholesterol; Diet | 2014 |
Pharmacological doses of niacin stimulate the expression of genes involved in carnitine uptake and biosynthesis and improve the carnitine status of obese Zucker rats.
Topics: Aldehyde Oxidoreductases; Animals; Base Sequence; Carnitine; DNA Primers; gamma-Butyrobetaine Dioxyg | 2014 |
Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes.
Topics: Animals; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Hypertriglyceridemia; Hypoglycemic Agents | 2015 |
Pharmacokinetic and pharmacological effects of β-hydroxyphosphocarnitine in animal models.
Topics: Administration, Oral; Animals; Area Under Curve; Carnitine; Cholesterol; Fatty Liver; Half-Life; Ins | 2014 |
L-Carnitine: a new insight into the pathogenesis of endometrial cancer.
Topics: Adult; Aged; Body Mass Index; Carcinoma, Endometrioid; Carnitine; Case-Control Studies; Endometrial | 2015 |
Acylcarnitines: potential implications for skeletal muscle insulin resistance.
Topics: Adult; Animals; Antioxidants; Carnitine; Case-Control Studies; Cell Line; Cells, Cultured; Cytokines | 2015 |
Nutritional status and carnitine level in kidney transplant recipients.
Topics: Adult; Aged; Body Mass Index; Carnitine; Female; Hand Strength; Humans; Kidney Diseases; Kidney Tran | 2014 |
L-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder.
Topics: Abdominal Fat; Animals; Body Weight; Carnitine; Disease Models, Animal; Feeding Behavior; Gene Expre | 2015 |
Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload differentially impact fast- versus slow-twitch muscle contractile function in C57BL/6J mice.
Topics: Acyl-CoA Dehydrogenase; Allostasis; Animals; Carnitine; Diet, Fat-Restricted; Diet, High-Fat; Electr | 2015 |
Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning.
Topics: Adaptation, Physiological; Adiposity; Animals; Blood Glucose; Body Weight; Butyric Acid; Carnitine; | 2015 |
[The use of complex tools ezetimibe, hepadyfu fosinopril and correction of blood pressure and endothelial dysfunction in patients with nonalcoholic steatohepatitis and essential hypertension stage II].
Topics: Adenine; Anticholesteremic Agents; Azetidines; Carnitine; Drug Combinations; Endothelium, Vascular; | 2014 |
Metabolomic analysis reveals altered skeletal muscle amino acid and fatty acid handling in obese humans.
Topics: Adult; Amino Acids; Carnitine; Diet, High-Fat; Energy Metabolism; Fatty Acids; Humans; Lipid Metabol | 2015 |
Modulation of tissue fatty acids by L-carnitine attenuates metabolic syndrome in diet-induced obese rats.
Topics: Animals; Carnitine; Diet, High-Fat; Dietary Carbohydrates; Dietary Supplements; Humans; Lipid Metabo | 2015 |
Natural weight loss supplements - Are they psychoactive?
Topics: Adult; Anti-Obesity Agents; Carnitine; Dietary Supplements; Female; Garcinia cambogia; Humans; Obesi | 2016 |
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Topics: Adult; Atherosclerosis; Bariatric Surgery; Betaine; Body Mass Index; Cardiovascular Diseases; Carnit | 2016 |
The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice.
Topics: Animals; Betaine; Carnitine; Dietary Fats; Energy Metabolism; Glucose Intolerance; Insulin Resistanc | 2016 |
Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy.
Topics: Absorptiometry, Photon; Adipose Tissue; Adiposity; Adult; Amino Acids, Branched-Chain; Anti-Retrovir | 2016 |
Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice.
Topics: Amino Acids; Analysis of Variance; Animals; Biomarkers; Blood Glucose; Carnitine; Cluster Analysis; | 2016 |
Effect of Exercise and Calorie Restriction on Tissue Acylcarnitines, Tissue Desaturase Indices, and Fat Accumulation in Diet-Induced Obese Rats.
Topics: Animals; Caloric Restriction; Carnitine; Diet, High-Fat; Disease Models, Animal; Fatty Acid Desatura | 2016 |
Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status.
Topics: Adult; Amino Acids; Body Mass Index; Cardiovascular Diseases; Carnitine; Cholesterol; Cholesterol, H | 2016 |
Cats in Positive Energy Balance Have Lower Rates of Adipose Gain When Fed Diets Containing 188 versus 121 ppm L-Carnitine.
Topics: Adiposity; Animal Feed; Animals; Carnitine; Cats; Diet; Energy Metabolism; Obesity | 2016 |
Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons.
Topics: Adenosine Triphosphate; Adult; Amino Acids, Branched-Chain; Biomarkers; Carnitine; Citric Acid Cycle | 2017 |
Cardiovascular Risk Factors Associated With Blood Metabolite Concentrations and Their Alterations During a 4-Year Period in a Population-Based Cohort.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Amino Acids; Biomarkers; Body Mass Index; Cardiovascular | 2016 |
Plasma L-carnitine levels of obese and non-obese polycystic ovary syndrome patients.
Topics: Adolescent; Adult; Body Mass Index; Carnitine; Case-Control Studies; Cross-Sectional Studies; Female | 2017 |
Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Carnitine O-Acetyltransferas | 2017 |
Serum Chemerin in Obese Children and Adolescents Before and After L-Carnitine Therapy: Relation to Nonalcoholic Fatty Liver Disease and Other Features of Metabolic Syndrome.
Topics: Adolescent; Antioxidants; Biomarkers; Carnitine; Case-Control Studies; Chemokines; Child; Child, Pre | 2016 |
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E
Topics: Acetates; Animals; Apolipoproteins E; Atherosclerosis; Atorvastatin; beta-Glucans; Butyrates; Cardio | 2017 |
Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women.
Topics: Adult; Aged; Aged, 80 and over; Black or African American; Carnitine; Citric Acid Cycle; Diabetes Me | 2009 |
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
Topics: Adolescent; Adult; Aged; Amino Acids; Blood Glucose; Carnitine; Cross-Sectional Studies; Fatty Acids | 2009 |
Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats.
Topics: Animals; Carnitine; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2009 |
Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity.
Topics: Adult; Biomarkers; Body Mass Index; Carnitine; Diabetes Mellitus, Type 2; Fasting; Glucose Clamp Tec | 2010 |
Stevia rebaudiana Bertoni extract supplementation improves lipid and carnitine profiles in C57BL/6J mice fed a high-fat diet.
Topics: Animals; Body Weight; Carnitine; Dietary Fats; Dietary Sucrose; Dietary Supplements; Enzymes; Hyperc | 2010 |
Metabolic profiling of muscle contraction in lean compared with obese rodents.
Topics: Acetyl-CoA Carboxylase; Animals; Biological Transport; Carnitine; Glucose; Glycogen; Lactic Acid; Li | 2010 |
Effects of oral L-carnitine supplementation on insulin sensitivity indices in response to glucose feeding in lean and overweight/obese males.
Topics: Adipose Tissue; Administration, Oral; Adolescent; Adult; Blood Glucose; Body Mass Index; Carnitine; | 2011 |
A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals.
Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Carnitine; Diet; Dietary Fats; Fatty Acids, Nones | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice.
Topics: Adipose Tissue; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carnitine; | 2011 |
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system.
Topics: Adipocytes; Carnitine; Coculture Techniques; Fatty Acids, Nonesterified; Female; Gene Expression; Gl | 2011 |
Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases.
Topics: Animals; Cardiovascular Diseases; Carnitine; Dietary Fats; Fatty Liver; Glycine max; Isoflavones; Li | 2011 |
Regular endurance exercise improves the diminished hepatic carnitine status in mice fed a high-fat diet.
Topics: Acetylcarnitine; Animals; Body Weight; Carnitine; Diet, High-Fat; Fatty Acids; Gene Expression Regul | 2011 |
Metabolomic profiling of fatty acid and amino acid metabolism in youth with obesity and type 2 diabetes: evidence for enhanced mitochondrial oxidation.
Topics: Absorptiometry, Photon; Adolescent; Amino Acids; Carnitine; Diabetes Mellitus, Type 2; Fasting; Fatt | 2012 |
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation.
Topics: Adipose Tissue; Amino Acids; Analysis of Variance; Animals; Biomarkers; Blotting, Western; Carnitine | 2012 |
Pharmacological evaluation of a β-hydroxyphosphonate analogue of l-carnitine in obese Zucker fa/fa rats.
Topics: Animals; Carnitine; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; | 2013 |
Consumption of a high β-glucan barley flour improves glucose control and fatty liver and increases muscle acylcarnitines in the Zucker diabetic fatty rat.
Topics: Adiponectin; Animals; beta-Glucans; Blood Glucose; Body Weight; Carnitine; Cholesterol; Diabetes Mel | 2013 |
[Dietary supplements and functional food for weight reduction -- expectations and reality].
Topics: Anti-Obesity Agents; Carnitine; Citrates; Controlled Clinical Trials as Topic; Dietary Supplements; | 2003 |
The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects.
Topics: Adolescent; Adult; Algorithms; Body Composition; Body Water; Carnitine; Dietary Fats; Dietary Supple | 2004 |
[The influence of panthotenic acid mitochondrial oxidation and oxidative phosphorylation in liver of rats with alimentary obesity].
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids; Female; Mitochondria, Liver; Obes | 2004 |
Acanthopanax senticosus extract prepared from cultured cells decreases adiposity and obesity indices in C57BL/6J mice fed a high fat diet.
Topics: Adipose Tissue; Administration, Oral; Animals; Carnitine; Cholesterol, LDL; Dietary Fats; Eleutheroc | 2004 |
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.
Topics: Animals; Carnitine; Coenzyme A; Dietary Fats; Dietary Sucrose; Fatty Liver; Female; Glycerol-3-Phosp | 2005 |
Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Coenzyme A Ligases; Diet; Diet | 2006 |
Changes in plasma carnitine levels after jejunoileal bypass.
Topics: Carnitine; Female; Humans; Ileum; Jejunum; Male; Obesity | 1980 |
Acute hormonal effects on carnitine metabolism in thin and obese subjects: responses to somatostatin, glucagon, and insulin.
Topics: Adult; Blood Glucose; Carnitine; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Hu | 1981 |
Oral L-carnitine administration after jejunoileal by-pass surgery.
Topics: 3-Hydroxybutyric Acid; Carnitine; Fasting; Fatty Acids, Nonesterified; Female; Humans; Hydroxybutyra | 1984 |
Decreased carnitine uptake in cultured cells from a woman with endogenous obesity.
Topics: Carnitine; Cells, Cultured; Female; Fibroblasts; Humans; Obesity | 1983 |
Oxidation and ketogenesis in hepatocytes of lean and obese Zucker rats.
Topics: Animals; Carbon Dioxide; Carnitine; Fasting; Female; Food; Glucagon; Glucose; Ketone Bodies; Liver; | 1982 |
Urinary excretion of acetylcarnitine during human diabetic and fasting ketosis.
Topics: Acetylcarnitine; Acidosis; Adolescent; Adult; Aged; Body Weight; Carnitine; Child; Diabetic Ketoacid | 1982 |
A note on "orthomolecular aids for dieting"--myasthenic syndrome due to dl-carnitine.
Topics: Animals; Anuria; Carnitine; Humans; Neuromuscular Diseases; Obesity; Rats; Syndrome | 1982 |
Carnitine metabolism in normal-weight and obese human subjects during fasting.
Topics: Adult; Body Weight; Carnitine; Fasting; Female; Humans; Middle Aged; Obesity | 1980 |
Increased liver carnitine content in obese women.
Topics: Adult; Animals; Carnitine; Fatty Acids; Fatty Liver; Female; Humans; Insulin; Liver; Middle Aged; Mu | 1995 |
Changes in carnitine metabolism with ketone body production in obese glucose-intolerant patients.
Topics: Acylation; Adult; Blood Glucose; Carnitine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose In | 1995 |
Utility of metformin as an adjunct to hydroxycitrate/carnitine for reducing body fat in diabetics.
Topics: Adipose Tissue; Body Composition; Carnitine; Citrates; Diabetes Mellitus; Humans; Hypoglycemic Agent | 1998 |
Lipid oxidation is reduced in obese human skeletal muscle.
Topics: Adult; Body Mass Index; Caprylates; Carbon Isotopes; Carnitine; Carnitine O-Palmitoyltransferase; Ci | 2000 |
The effect of pivalate treatment of pregnant rats on body mass and insulin levels in the adult offspring.
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Blood Glucose; Carnitine; Female; Hyperinsulinism; | 2001 |
Dietary L-carnitine supplementation in obese cats alters carnitine metabolism and decreases ketosis during fasting and induced hepatic lipidosis.
Topics: 3-Hydroxybutyric Acid; Animals; Carnitine; Cat Diseases; Cats; Dietary Supplements; Fasting; Fatty A | 2002 |
Plasma carnitine and body composition.
Topics: Adult; Age Factors; Aged; Body Composition; Body Constitution; Body Water; Carnitine; Cholesterol; C | 1976 |
Plasma and urinary carnitine of obese subjects on very-low-calorie diets.
Topics: Carnitine; Diet, Reducing; Dietary Fats; Female; Food, Formulated; Humans; Obesity; Weight Loss | 1990 |
An explanation for decreased ketogenesis in the liver of the obese Zucker rat.
Topics: Animals; Carnitine; Cytosol; DNA; Electron Transport Complex IV; Ketone Bodies; Liver; Male; Mitocho | 1989 |
Pharmacologic action of L-carnitine on hypertriglyceridemia in obese Zucker rats.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; DNA; Feces; Female; Hyperlipoproteinemia Type | 1986 |
Carnitine metabolism in lean and obese Zucker rats during starvation.
Topics: Animals; Body Weight; Carnitine; DNA; Female; Liver; Obesity; Proteins; Rats; Rats, Zucker; Starvati | 1986 |
Citrate and the conversion of carbohydrate into fat.
Topics: Acetates; Acyltransferases; Animals; Carbohydrate Metabolism; Carnitine; Citrates; Coenzyme A; Diabe | 1968 |