Page last updated: 2024-10-16

carnitine and Melanoma

carnitine has been researched along with Melanoma in 4 studies

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"The cytotoxic effect of azelaic acid on murine melanoma cells in culture is due, at least in part, to an antimitochondrial action."7.67Effect of L-carnitine on cultured murine melanoma cells exposed to azelaic acid. ( Bhasin, YP; Breathnach, AS; Ethridge, L; Nazzaro-Porro, M; Passi, S; Robins, EJ; Ward, BJ, 1986)
"Circulating tumor cells are the key link between a primary tumor and distant metastases, but once in the bloodstream, loss of adhesion induces cell death."5.91The Regulators of Peroxisomal Acyl-Carnitine Shuttle CROT and CRAT Promote Metastasis in Melanoma. ( Aldaz, P; Arozarena, I; Bocanegra, A; Feliu, I; Fernandez-Irigoyen, J; Gomez-Cabrero, D; Larrayoz, IM; Lasheras-Otero, I; Lecanda, F; Maillo, A; Moreno, H; Olias-Arjona, A; Redondo-Muñoz, M; Santamaria, E; Vicent, S; Wellbrock, C, 2023)
"The cytotoxic effect of azelaic acid on murine melanoma cells in culture is due, at least in part, to an antimitochondrial action."3.67Effect of L-carnitine on cultured murine melanoma cells exposed to azelaic acid. ( Bhasin, YP; Breathnach, AS; Ethridge, L; Nazzaro-Porro, M; Passi, S; Robins, EJ; Ward, BJ, 1986)
"Circulating tumor cells are the key link between a primary tumor and distant metastases, but once in the bloodstream, loss of adhesion induces cell death."1.91The Regulators of Peroxisomal Acyl-Carnitine Shuttle CROT and CRAT Promote Metastasis in Melanoma. ( Aldaz, P; Arozarena, I; Bocanegra, A; Feliu, I; Fernandez-Irigoyen, J; Gomez-Cabrero, D; Larrayoz, IM; Lasheras-Otero, I; Lecanda, F; Maillo, A; Moreno, H; Olias-Arjona, A; Redondo-Muñoz, M; Santamaria, E; Vicent, S; Wellbrock, C, 2023)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Lasheras-Otero, I1
Feliu, I1
Maillo, A1
Moreno, H1
Redondo-Muñoz, M1
Aldaz, P1
Bocanegra, A1
Olias-Arjona, A1
Lecanda, F1
Fernandez-Irigoyen, J1
Santamaria, E1
Larrayoz, IM1
Gomez-Cabrero, D1
Wellbrock, C1
Vicent, S1
Arozarena, I1
Mazar, J1
Zhao, W1
Khalil, AM1
Lee, B1
Shelley, J1
Govindarajan, SS1
Yamamoto, F1
Ratnam, M1
Aftab, MN1
Collins, S1
Finck, BN1
Han, X1
Mattick, JS1
Dinger, ME1
Perera, RJ1
Vescovi, G1
Weber, B1
Matrat, M1
Ramacci, C1
Nabet, P1
Kremer, B1
Ward, BJ1
Breathnach, AS1
Robins, EJ1
Bhasin, YP1
Ethridge, L1
Nazzaro-Porro, M1
Passi, S1

Other Studies

4 other studies available for carnitine and Melanoma

ArticleYear
The Regulators of Peroxisomal Acyl-Carnitine Shuttle CROT and CRAT Promote Metastasis in Melanoma.
    The Journal of investigative dermatology, 2023, Volume: 143, Issue:2

    Topics: Animals; Carnitine; Carnitine Acyltransferases; Carnitine O-Acetyltransferase; Fatty Acids; Melanoma

2023
The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells.
    Oncotarget, 2014, Oct-15, Volume: 5, Issue:19

    Topics: Apoptosis; Carnitine; Cell Line, Tumor; Cell Proliferation; Diacylglycerol O-Acyltransferase; Humans

2014
Modulation by palmitoyl-carnitine of calcium activated, phospholipid-dependent protein kinase activity and inhibition of melanoma cell growth.
    The British journal of dermatology, 1988, Volume: 119, Issue:2

    Topics: Adult; Carnitine; Cell Survival; Cytosol; Humans; Male; Melanoma; Palmitoylcarnitine; Protein Kinase

1988
Effect of L-carnitine on cultured murine melanoma cells exposed to azelaic acid.
    The Journal of investigative dermatology, 1986, Volume: 86, Issue:4

    Topics: Animals; Antineoplastic Agents; Carnitine; Cell Line; Dicarboxylic Acids; Melanoma; Mice; Mitochondr

1986