carnitine has been researched along with Left Ventricular Dysfunction in 20 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of L-propionylcarnitine on patients with left ventricular dysfunction (EF < 45%) NYHA class II, symptomatic despite therapy with digitalis and diuretics was evaluated in a phase II parallel, double-blind, randomized, placebo-controlled study." | 9.07 | Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction. ( Brunelli, C; Canale, C; Caponnetto, S; Masperone, MA; Terracchini, V; Valentini, G, 1994) |
| "These results indicate that metabolic therapy with propionyl L-carnitine may attenuate defects in the SL membrane and thus may improve heart function in congestive heart failure due to myocardial infarction." | 7.70 | Beneficial effects of propionyl L-carnitine on sarcolemmal changes in congestive heart failure due to myocardial infarction. ( Dhalla, KS; Dhalla, NS; Ferrari, R; Ganguly, PK; Sethi, R, 1999) |
| "During myocardial ischemia, inhibition of the carnitine-mediated transportation of fatty acid may be beneficial because it facilitates glucose utilization and prevents an accumulation of fatty acid metabolites." | 7.69 | Inhibition of carnitine synthesis protects against left ventricular dysfunction in rats with myocardial ischemia. ( Aoyagi, T; Eto, Y; Hayashi, Y; Kirimoto, T; Kobayakawa, N; Matsumoto, A; Momomura, S; Omata, M; Sugiura, S; Yokoyama, I; Yonekura, K, 1997) |
| "Carnitine is an essential amino acid involved in transporting fatty acids across the mitochondrial membrane." | 5.91 | Effect of Carnitine Supplementation in Pediatric Patients with Left Ventricular Dysfunction. ( Dorsey, V; Ikeda, N; Loomba, RS; Nelson-McMillan, K; Patel, R; Yousaf, F, 2023) |
| "Supplementation results in higher myocardial CoQ10, taurine, and carnitine levels and is associated with a reduction in left ventricular end-diastolic volume in patients with left ventricular dysfunction before revascularization." | 5.10 | Nutritional supplementation with MyoVive repletes essential cardiac myocyte nutrients and reduces left ventricular size in patients with left ventricular dysfunction. ( Barr, A; Errett, L; Freeman, M; Jeejeebhoy, F; Keith, M; Kurian, R; Mazer, D; McCall, M, 2002) |
| "The effect of L-propionylcarnitine on patients with left ventricular dysfunction (EF < 45%) NYHA class II, symptomatic despite therapy with digitalis and diuretics was evaluated in a phase II parallel, double-blind, randomized, placebo-controlled study." | 5.07 | Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction. ( Brunelli, C; Canale, C; Caponnetto, S; Masperone, MA; Terracchini, V; Valentini, G, 1994) |
| "These results indicate that metabolic therapy with propionyl L-carnitine may attenuate defects in the SL membrane and thus may improve heart function in congestive heart failure due to myocardial infarction." | 3.70 | Beneficial effects of propionyl L-carnitine on sarcolemmal changes in congestive heart failure due to myocardial infarction. ( Dhalla, KS; Dhalla, NS; Ferrari, R; Ganguly, PK; Sethi, R, 1999) |
| "During myocardial ischemia, inhibition of the carnitine-mediated transportation of fatty acid may be beneficial because it facilitates glucose utilization and prevents an accumulation of fatty acid metabolites." | 3.69 | Inhibition of carnitine synthesis protects against left ventricular dysfunction in rats with myocardial ischemia. ( Aoyagi, T; Eto, Y; Hayashi, Y; Kirimoto, T; Kobayakawa, N; Matsumoto, A; Momomura, S; Omata, M; Sugiura, S; Yokoyama, I; Yonekura, K, 1997) |
| "L-Carnitine plays a role in the utilization of fatty acids and glucose in the myocardium." | 2.69 | Plasma carnitine levels as a marker of impaired left ventricular functions. ( Aleem, SA; El-Aroussy, W; El-Tobgy, S; Mayhoub, G; Mokhtar, MS; Rizk, A, 2000) |
| "Carnitine is a naturally occurring compound that is essential in energy metabolism of the mammalian heart." | 2.43 | Hypocarnitinaemia induced by sodium pivalate in the rat is associated with left ventricular dysfunction and impaired energy metabolism. ( Broderick, TL, 2006) |
| "Carnitine is an essential amino acid involved in transporting fatty acids across the mitochondrial membrane." | 1.91 | Effect of Carnitine Supplementation in Pediatric Patients with Left Ventricular Dysfunction. ( Dorsey, V; Ikeda, N; Loomba, RS; Nelson-McMillan, K; Patel, R; Yousaf, F, 2023) |
| "The study investigates the effects of choline deficiency on myocardial performance in adult rats and the possible modifications after carnitine administration." | 1.39 | Heart dysfunction induced by choline-deficiency in adult rats: the protective role of L-carnitine. ( Douzis, ICh; Karkalousos, PL; Lazaris, AC; Liapi, CA; Mourouzis, IS; Pantos, CI; Perelas, AI; Strilakou, AA; Stylianaki, AT, 2013) |
| " The dosage of erythropoietin was also monitored during the study and the patients' clinical status was assessed by a questionnaire." | 1.31 | Beneficial effects of L-carnitine in dialysis patients with impaired left ventricular function: an observational study. ( Carraro, G; Lidestri, V; Naso, A; Romagnoli, GF, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (30.00) | 18.2507 |
| 2000's | 11 (55.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeda, N | 1 |
| Loomba, RS | 1 |
| Patel, R | 1 |
| Dorsey, V | 1 |
| Yousaf, F | 1 |
| Nelson-McMillan, K | 1 |
| Strilakou, AA | 1 |
| Lazaris, AC | 1 |
| Perelas, AI | 1 |
| Mourouzis, IS | 1 |
| Douzis, ICh | 1 |
| Karkalousos, PL | 1 |
| Stylianaki, AT | 1 |
| Pantos, CI | 1 |
| Liapi, CA | 1 |
| Turer, AT | 1 |
| Stevens, RD | 1 |
| Bain, JR | 1 |
| Muehlbauer, MJ | 1 |
| van der Westhuizen, J | 1 |
| Mathew, JP | 1 |
| Schwinn, DA | 1 |
| Glower, DD | 1 |
| Newgard, CB | 1 |
| Podgoreanu, MV | 1 |
| Stride, N | 1 |
| Larsen, S | 1 |
| Hey-Mogensen, M | 1 |
| Sander, K | 1 |
| Lund, JT | 1 |
| Gustafsson, F | 1 |
| Køber, L | 1 |
| Dela, F | 1 |
| Boles, RG | 1 |
| Buziashvili, IuI | 1 |
| Kliuchnikov, IV | 1 |
| Melkonian, AM | 1 |
| Inozemtseva, EV | 1 |
| Kovalenko, OA | 1 |
| Mamaev, KhK | 1 |
| Steiber, AL | 1 |
| Weatherspoon, LJ | 1 |
| Spry, L | 1 |
| Davis, AT | 1 |
| Broderick, TL | 1 |
| Yamak, A | 1 |
| Bitar, F | 1 |
| Karam, P | 1 |
| Nemer, G | 1 |
| Caponnetto, S | 1 |
| Canale, C | 1 |
| Masperone, MA | 1 |
| Terracchini, V | 1 |
| Valentini, G | 1 |
| Brunelli, C | 1 |
| Bianchi, G | 1 |
| Rizzon, P | 1 |
| Iliceto, S | 1 |
| Aoyagi, T | 1 |
| Sugiura, S | 1 |
| Eto, Y | 1 |
| Yonekura, K | 1 |
| Matsumoto, A | 1 |
| Yokoyama, I | 1 |
| Kobayakawa, N | 1 |
| Omata, M | 1 |
| Kirimoto, T | 1 |
| Hayashi, Y | 1 |
| Momomura, S | 1 |
| Terada, R | 1 |
| Matsubara, T | 1 |
| Koh, N | 1 |
| Nakamura, J | 1 |
| Hotta, N | 1 |
| Sethi, R | 1 |
| Dhalla, KS | 1 |
| Ganguly, PK | 1 |
| Ferrari, R | 1 |
| Dhalla, NS | 1 |
| El-Aroussy, W | 1 |
| Rizk, A | 1 |
| Mayhoub, G | 1 |
| Aleem, SA | 1 |
| El-Tobgy, S | 1 |
| Mokhtar, MS | 1 |
| Hayashi, K | 1 |
| Okumura, K | 1 |
| Matsui, H | 1 |
| Murase, K | 1 |
| Kamiya, H | 1 |
| Saburi, Y | 1 |
| Numaguchi, Y | 1 |
| Toki, Y | 1 |
| Hayakawa, T | 1 |
| Mc Entee, K | 1 |
| Flandre, T | 1 |
| Dessy, C | 1 |
| Desmecht, D | 1 |
| Clercx, C | 1 |
| Balligand, M | 1 |
| Michaux, C | 1 |
| Jonville, E | 1 |
| Miserque, N | 1 |
| Henroteaux, M | 1 |
| Keene, B | 1 |
| Jeejeebhoy, F | 1 |
| Keith, M | 1 |
| Freeman, M | 1 |
| Barr, A | 1 |
| McCall, M | 1 |
| Kurian, R | 1 |
| Mazer, D | 1 |
| Errett, L | 1 |
| Romagnoli, GF | 1 |
| Naso, A | 1 |
| Carraro, G | 1 |
| Lidestri, V | 1 |
2 reviews available for carnitine and Left Ventricular Dysfunction
| Article | Year |
|---|---|
[Ischemic remodeling of the left ventricle (definition, pathogenesis, diagnosis, medical and surgical correction)].
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitor | 2002 |
Hypocarnitinaemia induced by sodium pivalate in the rat is associated with left ventricular dysfunction and impaired energy metabolism.
Topics: Animals; Carnitine; Energy Metabolism; Models, Animal; Myocardium; Pentanoic Acids; Rats; Ventricula | 2006 |
3 trials available for carnitine and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction.
Topics: Adult; Aged; Cardiotonic Agents; Carnitine; Double-Blind Method; Echocardiography, Doppler; Exercise | 1994 |
Plasma carnitine levels as a marker of impaired left ventricular functions.
Topics: Adult; Aged; Biomarkers; Cardiomyopathy, Dilated; Carnitine; Female; Heart Failure; Humans; Male; Mi | 2000 |
Nutritional supplementation with MyoVive repletes essential cardiac myocyte nutrients and reduces left ventricular size in patients with left ventricular dysfunction.
Topics: Aged; Carnitine; Coenzymes; Dietary Supplements; Double-Blind Method; Female; Heart Failure; Humans; | 2002 |
15 other studies available for carnitine and Left Ventricular Dysfunction
| Article | Year |
|---|---|
Effect of Carnitine Supplementation in Pediatric Patients with Left Ventricular Dysfunction.
Topics: Adult; Carnitine; Child; Dietary Supplements; Fatty Acids; Humans; Retrospective Studies; Stroke Vol | 2023 |
Heart dysfunction induced by choline-deficiency in adult rats: the protective role of L-carnitine.
Topics: Animals; Cardiotonic Agents; Carnitine; Choline Deficiency; Dietary Supplements; Edema, Cardiac; Fib | 2013 |
Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.
Topics: Aged; Anaerobic Threshold; Cardiac Output; Cardiopulmonary Bypass; Carnitine; Coronary Artery Diseas | 2009 |
Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunction.
Topics: Aged; Biopsy; Carnitine; Creatine; Creatine Kinase, Mitochondrial Form; Energy Metabolism; Fatty Aci | 2013 |
Very long-chain acyl-CoA dehydrogenase deficiency in an infant presenting with massive hepatomegaly.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Cardiomyopathies; Carnitine; Diet; Gastroenteritis; Hepatomegaly | 2002 |
Serum carnitine concentrations correlated to clinical outcome parameters in chronic hemodialysis patients.
Topics: Age Factors; Blood Urea Nitrogen; Carnitine; Diabetes Complications; Diabetes Mellitus; Female; Huma | 2004 |
Exclusive cardiac dysfunction in familial primary carnitine deficiency cases: a genotype-phenotype correlation.
Topics: Base Sequence; Cardiomyopathy, Dilated; Carnitine; Child; Child, Preschool; Codon, Nonsense; DNA, Co | 2007 |
[Rationale for metabolic treatment of left ventricular dysfunction].
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Carnitine; Humans; Myocardium; Phosphocreatine; | 1995 |
[L-carnitine in the treatment of left ventricular dysfunction in post-infarction].
Topics: Animals; Carnitine; Humans; Myocardial Infarction; Myocardial Ischemia; Ventricular Dysfunction, Lef | 1995 |
Inhibition of carnitine synthesis protects against left ventricular dysfunction in rats with myocardial ischemia.
Topics: Animals; Carnitine; Hypoxia; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Ventricular Dysf | 1997 |
Effects of propionyl-L-carnitine on cardiac dysfunction in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Expe | 1998 |
Beneficial effects of propionyl L-carnitine on sarcolemmal changes in congestive heart failure due to myocardial infarction.
Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Carnitine; Heart Failu | 1999 |
Involvement of 1,2-diacylglycerol in improvement of heart function by etomoxir in diabetic rats.
Topics: Animals; Blood Pressure; Carnitine; Ceramides; Diabetes Mellitus, Experimental; Diglycerides; Echoca | 2001 |
Metabolic and structural abnormalities in dogs with early left ventricular dysfunction induced by incessant tachycardia.
Topics: Animals; Biopsy; Carnitine; Dog Diseases; Dogs; Histocytochemistry; Male; Microscopy, Electron; Myoc | 2001 |
Beneficial effects of L-carnitine in dialysis patients with impaired left ventricular function: an observational study.
Topics: Aged; Carnitine; Echocardiography; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Obser | 2002 |