carnitine has been researched along with Intellectual Disability in 16 studies
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| " After successful supplementation, smaller dosage of L-carnitine (100 or 300 mg/day) was enough to maintain the normal levels." | 2.80 | [Supplementation of L-carnitine to the severe motor and intellectual disabilities fed with enteral carnitine-deficient formulas for years]. ( Taguchi, K; Tsuneishi, S; Yagi, R, 2015) |
| "Autism spectrum disorder (ASD) with intellectual disability (ID) is a life-long debilitating condition, which is characterized by cognitive function impairment and other neurological signs." | 1.42 | Autism and intellectual disability associated with mitochondrial disease and hyperlactacidemia. ( Cauli, O; González-Guevara, L; Guevara-Campos, J, 2015) |
| "Carnitine is a key molecule in energy metabolism that helps transport activated fatty acids into the mitochondria." | 1.40 | The effect of homozygous deletion of the BBOX1 and Fibin genes on carnitine level and acyl carnitine profile. ( Akrami, SM; Rashidi-Nezhad, A; Reymond, A; Saebnouri, H; Talebi, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Rose, L | 1 |
| Hall, K | 1 |
| Tang, S | 1 |
| Hasadsri, L | 1 |
| Kimonis, V | 1 |
| Ono, H | 1 |
| Rashidi-Nezhad, A | 1 |
| Talebi, S | 1 |
| Saebnouri, H | 1 |
| Akrami, SM | 1 |
| Reymond, A | 1 |
| Guevara-Campos, J | 1 |
| González-Guevara, L | 1 |
| Cauli, O | 1 |
| Tsuneishi, S | 1 |
| Taguchi, K | 1 |
| Yagi, R | 1 |
| Mahfoud, A | 1 |
| Domínguez, CL | 1 |
| Rashed, M | 1 |
| Durán, M | 2 |
| Rodríguez, T | 1 |
| Rodríguez, D | 1 |
| Landa, V | 1 |
| Sempere, A | 1 |
| Arias, A | 1 |
| Farré, G | 1 |
| García-Villoria, J | 1 |
| Rodríguez-Pombo, P | 1 |
| Desviat, LR | 1 |
| Merinero, B | 1 |
| García-Cazorla, A | 1 |
| Vilaseca, MA | 1 |
| Ribes, A | 1 |
| Artuch, R | 1 |
| Campistol, J | 1 |
| Ly, TB | 1 |
| Peters, V | 1 |
| Gibson, KM | 1 |
| Liesert, M | 1 |
| Buckel, W | 1 |
| Wilcken, B | 1 |
| Carpenter, K | 1 |
| Ensenauer, R | 1 |
| Hoffmann, GF | 1 |
| Mack, M | 1 |
| Zschocke, J | 1 |
| Pascale, E | 1 |
| Battiloro, E | 1 |
| Cimino Reale, G | 1 |
| Pietrobono, R | 1 |
| Pomponi, MG | 1 |
| Chiurazzi, P | 1 |
| Nicolai, R | 1 |
| Calvani, M | 1 |
| Neri, G | 1 |
| D'Ambrosio, E | 1 |
| Matern, D | 1 |
| He, M | 1 |
| Berry, SA | 1 |
| Rinaldo, P | 1 |
| Whitley, CB | 1 |
| Madsen, PP | 1 |
| van Calcar, SC | 1 |
| Lussky, RC | 1 |
| Andresen, BS | 1 |
| Wolff, JA | 1 |
| Vockley, J | 1 |
| Samuraki, M | 1 |
| Komai, K | 1 |
| Hasegawa, Y | 1 |
| Kimura, M | 1 |
| Yamaguchi, S | 1 |
| Terada, N | 1 |
| Yamada, M | 1 |
| Steen, C | 1 |
| Baumgartner, ER | 1 |
| Lehnert, W | 1 |
| Suormala, T | 1 |
| Fingerhut, R | 1 |
| Stehn, M | 1 |
| Kohlschütter, A | 1 |
| Tóth, G | 1 |
| Morava, E | 1 |
| Bene, J | 1 |
| Selhorst, JJ | 1 |
| Overmars, H | 1 |
| Vreken, P | 1 |
| Molnár, J | 1 |
| Farkas, V | 1 |
| Melegh, B | 1 |
| Voit, T | 1 |
| Kramer, H | 1 |
| Thomas, C | 1 |
| Wechsler, W | 1 |
| Reichmann, H | 1 |
| Lenard, HG | 1 |
| Kimura, S | 1 |
| Miyake, S | 1 |
| Matsuda, I | 1 |
| Ohtani, Y | 1 |
| Ninomiya, N | 1 |
1 review available for carnitine and Intellectual Disability
| Article | Year |
|---|---|
Prospective diagnosis of 2-methylbutyryl-CoA dehydrogenase deficiency in the Hmong population by newborn screening using tandem mass spectrometry.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Diagnosis, Differential; Diet, Protein-Restricted; | 2003 |
1 trial available for carnitine and Intellectual Disability
| Article | Year |
|---|---|
[Supplementation of L-carnitine to the severe motor and intellectual disabilities fed with enteral carnitine-deficient formulas for years].
Topics: Adolescent; Adult; Carnitine; Child; Child, Preschool; Dietary Supplements; Enteral Nutrition; Femal | 2015 |
14 other studies available for carnitine and Intellectual Disability
| Article | Year |
|---|---|
Homozygous B4GALNT1 mutation and biochemical glutaric acidemia type II: A case report.
Topics: Adult; Carnitine; Epilepsy, Temporal Lobe; Female; Frameshift Mutation; Homozygote; Humans; Intellec | 2020 |
Sodium valproate-induced Fanconi syndrome in two severely disabled patients receiving carnitine supplementation.
Topics: Adult; Anticonvulsants; Carnitine; Disabled Persons; Epilepsy; Fanconi Syndrome; Female; Humans; Int | 2019 |
The effect of homozygous deletion of the BBOX1 and Fibin genes on carnitine level and acyl carnitine profile.
Topics: Abnormalities, Multiple; Calcinosis; Carnitine; Carrier Proteins; Child, Preschool; Chromosome Delet | 2014 |
Autism and intellectual disability associated with mitochondrial disease and hyperlactacidemia.
Topics: Carnitine; Child Development Disorders, Pervasive; Child, Preschool; Female; Folic Acid; Humans; Hyp | 2015 |
[D-2-hydroxyglutaric aciduria. Report of two cases].
Topics: Anticonvulsants; Atrophy; Brain; Brain Diseases, Metabolic, Inborn; Carnitine; Child, Preschool; Con | 2009 |
Study of inborn errors of metabolism in urine from patients with unexplained mental retardation.
Topics: Adenylosuccinate Lyase; Adolescent; Adult; Aged; Carnitine; Child; Child, Preschool; Chromium; Cohor | 2010 |
Mutations in the AUH gene cause 3-methylglutaconic aciduria type I.
Topics: Amino Acid Metabolism, Inborn Errors; Carnitine; Child, Preschool; Exons; Genes, Recessive; Glutarat | 2003 |
Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine.
Topics: Acetylcarnitine; Carnitine; Cells, Cultured; DNA Methylation; Fragile X Mental Retardation Protein; | 2003 |
A successfully treated adult patient with L-2-hydroxyglutaric aciduria.
Topics: Adult; Age Factors; Alcohol Oxidoreductases; Brain; Brain Diseases, Metabolic; Brain Diseases, Metab | 2008 |
Metabolic stroke in isolated 3-methylcrotonyl-CoA carboxylase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Carbon-Carbon Ligases; Carnitine; Diet, Protein-Restricted; Fa | 1999 |
Carnitine-responsive carnitine insufficiency in a case of mtDNA 8993T>C mutation associated Leigh syndrome.
Topics: Carnitine; Cerebellar Ataxia; Child; DNA, Mitochondrial; Humans; Intellectual Disability; Leigh Dise | 2001 |
Myopathy in Williams-Beuren syndrome.
Topics: Adult; Biopsy; Carnitine; Child; Child, Preschool; Contracture; Face; Female; Heart Defects, Congeni | 1991 |
Type II fiber myolysis in a patient with hypocarnitinemia.
Topics: Biopsy; Carnitine; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Intellectual Disabili | 1989 |
Renal handling of carnitine in children with carnitine deficiency and hyperammonemia associated with valproate therapy.
Topics: Ammonia; Carnitine; Epilepsy; Humans; Infant; Intellectual Disability; Kidney; Metabolic Clearance R | 1986 |