carnitine has been researched along with Insulin Sensitivity in 150 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "12-week L-carnitine supplementation in overweight or obese women with PCOS ameliorate insulin resistance, but has no effect on SHBG and lipid profile." | 9.51 | The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial. ( Fallahzadeh, H; Ghadiri-Anari, A; Hosseinzadeh, M; Nadjarzadeh, A; Pakravanfar, F; Sangouni, AA, 2022) |
| "With the available literature, carnitine seems to improve ovulation and clinical pregnancy and insulin resistance, BMI in women with PCOS." | 9.41 | Effects of carnitine on glucose and lipid metabolic profiles and fertility outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis. ( Cai, Q; Gong, Y; He, H; Jiang, T; Li, J; Shen, R; Shi, Y; Wang, Y; Wu, GL; Xiong, CL, 2023) |
| "Low carnitine status may underlie the development of insulin resistance and metabolic inflexibility." | 9.34 | L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility. ( Bruls, YMH; Havekes, B; Hesselink, MKC; Lindeboom, L; Moonen-Kornips, E; Op den Kamp, YJM; Phielix, E; Schaart, G; Schrauwen, P; Schrauwen-Hinderling, VB; Wildberger, JE, 2020) |
| "To compare clinical and metabolic profiles between N-acetylcysteine and l-carnitine among women with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS)." | 9.30 | Randomized controlled trial of N-acetylcysteine versus l-carnitine among women with clomiphene-citrate-resistant polycystic ovary syndrome. ( Abd El Aziz, WM; El Sharkwy, IA, 2019) |
| "In a prospective, randomized, double-blind, placebo-controlled trial, 60 overweight patients diagnosed with PCOS were randomized to receive either 250 mg carnitine supplements (n = 30) or placebo (n = 30) for 12 weeks." | 9.22 | Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. ( Asemi, Z; Ebrahimi, FA; Jamilian, M; Rahimi, M; Samimi, M; Tajbakhsh, B, 2016) |
| "Acylcarnitines, fatty acid oxidation (FAO) intermediates, have been implicated in diet-induced insulin resistance and type 2 diabetes mellitus, as increased levels are found in obese insulin resistant humans." | 9.22 | Assessment of plasma acylcarnitines before and after weight loss in obese subjects. ( Ambler, GK; Hollak, CE; Houten, SM; Miller, SR; Murgatroyd, PR; Napolitano, A; Nunez, DJ; Schooneman, MG; Soeters, MR; Tan, CY; Vidal-Puig, A; Virtue, S, 2016) |
| " We evaluate the efficacy of a peritoneal dialysis solution containing l-carnitine as an additive to improve insulin sensitivity." | 9.17 | Effect of an L-carnitine-containing peritoneal dialysate on insulin sensitivity in patients treated with CAPD: a 4-month, prospective, multicenter randomized trial. ( Arduini, A; Bertoli, S; Bonomini, M; Bosi, E; Cerasoli, P; Consoli, A; Corciulo, R; De Vecchi, A; Del Rosso, G; Di Castelnuovo, A; Di Liberato, L; Gesualdo, L; Giorgino, F; Marinangeli, G; Monaco, MP; Rossi, C; Russo, R; Shockley, T; Stingone, A, 2013) |
| "Preventing excessive/incomplete mitochondrial β-oxidation, characterised by perturbed carnitine metabolism, may be a mechanism by which PCT attenuates the reduction in postoperative insulin sensitivity." | 9.16 | Perioperative perturbations in carnitine metabolism are attenuated by preoperative carbohydrate treatment: Another mechanism by which preoperative feeding may attenuate development of postoperative insulin resistance. ( Awad, S; Lobo, DN; Shannon, C; Stephens, F, 2012) |
| "To evaluate the effects of 1-year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and inflammatory parameters in obese type 2 diabetic patients." | 9.15 | Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2011) |
| "Our study wants to evaluate the effects of one year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and insulin resistance state in type 2 diabetic patients." | 9.14 | Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2010) |
| "To evaluate the effects of one year of treatment with sibutramine plus L-carnitine compared to sibutramine on body weight, glycemic control, and insulin resistance state in type 2 diabetic patients." | 9.14 | Sibutramine and L-carnitine compared to sibutramine alone on insulin resistance in diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Gravina, A; Maffioli, P; Mereu, R; Palumbo, I; Randazzo, S; Salvadeo, SA, 2010) |
| "The present review provides an overview about data from both animal and human studies reporting effects of either carnitine supplementation or carnitine deficiency on parameters of glucose homeostasis and insulin sensitivity in order to establish the less well-recognized role of carnitine in regulating glucose homeostasis." | 8.88 | Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency. ( Eder, K; Keller, J; Ringseis, R, 2012) |
| "Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis." | 8.12 | High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022) |
| "To address this gap, this study evaluated insulin sensitivity and subcellular localization of intramuscular triacylglycerol, diacylglycerol, and sphingolipids as well as muscle acylcarnitines and serum lipidomics in people with obesity." | 8.02 | Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. ( Bergman, BC; Broussard, JL; Brozinick, JT; Bui, HH; D'Alessandro, A; Harrison, K; Macias, E; Milligan, P; Nemkov, T; Newsom, SA; Perreault, L; Roth, KD, 2021) |
| "Godex improved insulin resistance and steatosis by regulating carnitine acetyltransferase in liver in high-fat diet-fed mice." | 8.02 | Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway. ( Hong, JH; Lee, MK, 2021) |
| " Notably, genetic deletion of gpr27 elevated medium-chain acylcarnitines, in particular C6-hexanoylcarnitine, C8-octanoylcarnitine, C9-nonanoylcarnitine, and C10-decanoylcarnitine, lipid species known to be associated with insulin resistance in humans." | 7.96 | Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish. ( Chen, ZZ; Gerszten, RE; Kelley, ML; Li, Z; Ma, J; Nath, AK; Peterson, RT; Vitery, MDC; Yeh, JJ, 2020) |
| " Blood samples were taken after overnight fasting at baseline and three months into the study to assess the levels of fasting glucose, insulin, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), free testosterone, dehydroepiandrosterone (DHEA), and the insulin resistance index (HOMA-IR)." | 7.91 | Effects of L-carnitine on Polycystic Ovary Syndrome. ( Gachkar, L; Hoseini, S; Moghaddam, PB; Nazari, L; Salehpour, S, 2019) |
| "Circulating acyl-carnitines (acyl-CNTs) are associated with insulin resistance (IR) and type 2 diabetes (T2D) in both rodents and humans." | 7.85 | Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women. ( Abate, N; Asghar, R; Brasier, AR; Camacho-Hughes, M; Chondronikola, M; Dillon, EL; Durham, WJ; Porter, C; Sheffield-Moore, M; Sidossis, L; Tuvdendorj, D; Volpi, E; Wu, Z; Zhang, X; Zhao, Y, 2017) |
| "The important pathological consequences of insulin resistance arise from the detrimental effects of accumulated long-chain fatty acids and their respective acylcarnitines." | 7.83 | Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. ( Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Svalbe, B; Volska, K, 2016) |
| "Insulin resistance may be linked to incomplete fatty acid β-oxidation and the subsequent increase in acylcarnitine species in different tissues including skeletal muscle." | 7.81 | Acylcarnitines: potential implications for skeletal muscle insulin resistance. ( Adams, SH; Aguer, C; Dent, R; Harper, ME; Hwang, DH; Knotts, TA; McCoin, CS; McPherson, R; Ono-Moore, K; Thrush, AB, 2015) |
| "Acylcarnitine accumulation in skeletal muscle and plasma has been observed in numerous models of mitochondrial lipid overload and insulin resistance." | 7.80 | Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation. ( Barrett, DA; Cooper, S; Mansell, P; Mendis, B; Ortori, CA; Shannon, CE; Stephens, FB; Tsintzas, K, 2014) |
| "The objectives of the present study were to determine the effects of long-term oral administration of L-carnitine on insulin sensitivity, glucose disposal, plasma leptin concentrations and acylcarnitine spectrum both in plasma and urine." | 7.80 | The effect of long-term oral L-carnitine administration on insulin sensitivity, glucose disposal, plasma concentrations of leptin and acylcarnitines, and urinary acylcarnitine excretion in warmblood horses. ( Buyse, J; de Graaf-Roelfsema, E; de Sain-van der Velden, MG; Janssens, GP; Kranenburg, LC; van den Broek, J; van der Kolk, JH; Westermann, CM, 2014) |
| "To compare the effects of combined and individual supplementation of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats." | 7.79 | Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats. ( Ahmad, T; Anwar, MK; Hussain, MM; Khan, MA, 2013) |
| "Decreased total L-carnitine levels may be associated with hyperandrogenism and/or insulin resistance in non-obese women with PCOS." | 7.74 | Serum total L-carnitine levels in non-obese women with polycystic ovary syndrome. ( Fenkci, SM; Fenkci, V; Karagenc, N; Oztekin, O; Rota, S, 2008) |
| " We investigated the effect of dietary genistein (the principal soy isoflavone) alone and combined with L-carnitine to evaluate possible synergistic effects on the intentionally induced prediabetic state characterized by insulin resistance and obesity in C57Bl/6J mice fed a high-fat diet (HD)." | 7.73 | Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. ( Cha, YS; Lee, SJ; Park, HW; Yang, JY, 2006) |
| "Overweight patients with hyperlipidemia (serum triglyceride ≥ 1." | 6.80 | Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. ( Du, S; Jiang, S; Li, Y; Na, L; Niu, Y; Sun, C; Zhang, Q; Zhang, W, 2015) |
| "L-carnitine has also been shown to improve insulin sensitivity and elevate pyruvate dehydrogenase (PDH) flux." | 6.66 | The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD). ( Hodson, L; Neubauer, S; Pavlides, M; Savic, D, 2020) |
| "12-week L-carnitine supplementation in overweight or obese women with PCOS ameliorate insulin resistance, but has no effect on SHBG and lipid profile." | 5.51 | The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial. ( Fallahzadeh, H; Ghadiri-Anari, A; Hosseinzadeh, M; Nadjarzadeh, A; Pakravanfar, F; Sangouni, AA, 2022) |
| "Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood." | 5.48 | Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance. ( Ärnlöv, J; Berne, C; Broeckling, CD; Castillejo-Lopez, C; Cook, NL; Fall, T; Ganna, A; Giedraitis, V; Hetty, S; Ingelsson, E; Lind, L; Nowak, C; Prenni, JE; Salihovic, S; Shen, X; Sundström, J, 2018) |
| "Acylcarnitine accumulation has been linked to perturbations in energy metabolism pathways." | 5.46 | Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice. ( Antone, U; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Lola, D; Loza, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Vilks, K; Vilskersts, R; Volska, K, 2017) |
| "Obesity is associated with insulin resistance and impaired glucose tolerance, which represent characteristic features of the metabolic syndrome." | 5.43 | Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice. ( Bardova, K; Gardlo, A; Hansikova, J; Horakova, O; Kopecky, J; Kuda, O; Rombaldova, M; Rossmeisl, M, 2016) |
| "With the available literature, carnitine seems to improve ovulation and clinical pregnancy and insulin resistance, BMI in women with PCOS." | 5.41 | Effects of carnitine on glucose and lipid metabolic profiles and fertility outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis. ( Cai, Q; Gong, Y; He, H; Jiang, T; Li, J; Shen, R; Shi, Y; Wang, Y; Wu, GL; Xiong, CL, 2023) |
| "Low carnitine status may underlie the development of insulin resistance and metabolic inflexibility." | 5.34 | L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility. ( Bruls, YMH; Havekes, B; Hesselink, MKC; Lindeboom, L; Moonen-Kornips, E; Op den Kamp, YJM; Phielix, E; Schaart, G; Schrauwen, P; Schrauwen-Hinderling, VB; Wildberger, JE, 2020) |
| "Our findings underscore the importance of changes in TMAO, choline and L-carnitine in improving insulin sensitivity during a weight-loss intervention for obese patients." | 5.30 | Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. ( Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D, 2019) |
| "To evaluate the reproductive and metabolic effects of L-carnitine plus metformin in clomiphene citrate (CC) resistant obese polycystic ovary syndrome (PCOS) women." | 5.30 | l-Carnitine plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effects: a randomized clinical trial. ( El Sharkwy, I; Sharaf El-Din, M, 2019) |
| "To compare clinical and metabolic profiles between N-acetylcysteine and l-carnitine among women with clomiphene citrate (CC)-resistant polycystic ovary syndrome (PCOS)." | 5.30 | Randomized controlled trial of N-acetylcysteine versus l-carnitine among women with clomiphene-citrate-resistant polycystic ovary syndrome. ( Abd El Aziz, WM; El Sharkwy, IA, 2019) |
| "In a prospective, randomized, double-blind, placebo-controlled trial, 60 overweight patients diagnosed with PCOS were randomized to receive either 250 mg carnitine supplements (n = 30) or placebo (n = 30) for 12 weeks." | 5.22 | Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. ( Asemi, Z; Ebrahimi, FA; Jamilian, M; Rahimi, M; Samimi, M; Tajbakhsh, B, 2016) |
| "Acylcarnitines, fatty acid oxidation (FAO) intermediates, have been implicated in diet-induced insulin resistance and type 2 diabetes mellitus, as increased levels are found in obese insulin resistant humans." | 5.22 | Assessment of plasma acylcarnitines before and after weight loss in obese subjects. ( Ambler, GK; Hollak, CE; Houten, SM; Miller, SR; Murgatroyd, PR; Napolitano, A; Nunez, DJ; Schooneman, MG; Soeters, MR; Tan, CY; Vidal-Puig, A; Virtue, S, 2016) |
| " We evaluate the efficacy of a peritoneal dialysis solution containing l-carnitine as an additive to improve insulin sensitivity." | 5.17 | Effect of an L-carnitine-containing peritoneal dialysate on insulin sensitivity in patients treated with CAPD: a 4-month, prospective, multicenter randomized trial. ( Arduini, A; Bertoli, S; Bonomini, M; Bosi, E; Cerasoli, P; Consoli, A; Corciulo, R; De Vecchi, A; Del Rosso, G; Di Castelnuovo, A; Di Liberato, L; Gesualdo, L; Giorgino, F; Marinangeli, G; Monaco, MP; Rossi, C; Russo, R; Shockley, T; Stingone, A, 2013) |
| "This randomized, double blind, placebo-controlled, 8 week trial assessed the efficacy on metabolic changes produced by a consumption of a combination of bioactive food ingredients (epigallocatechin gallate, capsaicins, piperine and L-carnitine) versus a placebo, as part of a therapeutic 'lifestyle change' diet, in 86 overweight subjects." | 5.17 | Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months' consumption of a combination of bioactive food ingredients in overweight subjects. ( Castellaneta, E; Cava, E; Ceccarelli, P; Claudia, S; Donini, LM; Edda, C; Emanuela, C; Faliva, M; Fioravanti, M; Klersy, C; Luciano, S; Maddalena, P; Opizzi, A; Paola, C; Paolini, M; Perna, S; Rondanelli, M; Savina, C; Scavone, L; Solerte, SB, 2013) |
| "Preventing excessive/incomplete mitochondrial β-oxidation, characterised by perturbed carnitine metabolism, may be a mechanism by which PCT attenuates the reduction in postoperative insulin sensitivity." | 5.16 | Perioperative perturbations in carnitine metabolism are attenuated by preoperative carbohydrate treatment: Another mechanism by which preoperative feeding may attenuate development of postoperative insulin resistance. ( Awad, S; Lobo, DN; Shannon, C; Stephens, F, 2012) |
| "The aim of the study was to evaluate the effects of 12-month treatment with sibutramine plus L-carnitine compared with sibutramine alone on body weight, glycemic control, insulin resistance, and inflammatory state in type 2 diabetes mellitus patients." | 5.15 | Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Gravina, A; Maffioli, P; Mereu, R; Palumbo, I; Randazzo, S; Salvadeo, SA, 2011) |
| "To evaluate the effects of 1-year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and inflammatory parameters in obese type 2 diabetic patients." | 5.15 | Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2011) |
| "Our study wants to evaluate the effects of one year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and insulin resistance state in type 2 diabetic patients." | 5.14 | Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2010) |
| "To evaluate the effects of one year of treatment with sibutramine plus L-carnitine compared to sibutramine on body weight, glycemic control, and insulin resistance state in type 2 diabetic patients." | 5.14 | Sibutramine and L-carnitine compared to sibutramine alone on insulin resistance in diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Gravina, A; Maffioli, P; Mereu, R; Palumbo, I; Randazzo, S; Salvadeo, SA, 2010) |
| "To determine the effects of a weight loss program, including dietary modifications, increased physical activity and dietary supplement (L-carnitine or placebo) on anthropometrics, leptin, insulin, the metabolic syndrome (MS) and insulin resistance in overweight /obese premenopausal women." | 5.11 | Weight loss favorably modifies anthropometrics and reverses the metabolic syndrome in premenopausal women. ( Brownbill, RA; Fernandez, ML; Herron, KL; Ilich, JZ; Koo, SI; Lofgren, IE; West, KL; Zern, TL, 2005) |
| "L-carnitine constant infusion improves insulin sensitivity in insulin resistant diabetic patients; a significant effect on whole body insulin-mediated glucose uptake is also observed in normal subjects." | 5.09 | L-carnitine improves glucose disposal in type 2 diabetic patients. ( Benedetti, G; Capristo, E; De Gaetano, A; Gasbarrini, G; Giancaterini, A; Greco, AV; Mingrone, G, 1999) |
| " Evidence suggests that branched-chain amino acids, acylcarnitines and aromatic amino acids may play an early role on insulin resistance, exposing defects on amino acid metabolism, β-oxidation, and tricarboxylic acid cycle." | 4.93 | Metabolomics in diabetes, a review. ( Aguilar-Salinas, CA; Cruz-Bautista, I; Del Bosque-Plata, L; Pallares-Méndez, R, 2016) |
| "L-Carnitine combined with HDI may have helped with the calcium channel blocker (CCB) poisoning by decreasing insulin resistance, promoting intracellular glucose transport, facilitating the metabolism of free fatty acids, and increasing calcium channel sensitivity." | 4.89 | L-Carnitine for the treatment of a calcium channel blocker and metformin poisoning. ( Ajmo, I; Laliberté, M; Poirier, D; St-Onge, M, 2013) |
| "The present review provides an overview about data from both animal and human studies reporting effects of either carnitine supplementation or carnitine deficiency on parameters of glucose homeostasis and insulin sensitivity in order to establish the less well-recognized role of carnitine in regulating glucose homeostasis." | 4.88 | Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency. ( Eder, K; Keller, J; Ringseis, R, 2012) |
| " Perioperative metabolic conditioning using glutamine and L-carnitine may be used to modulate insulin sensitivity but further studies need to determine whether these interventions result in clinical benefit." | 4.88 | Metabolic conditioning to attenuate the adverse effects of perioperative fasting and improve patient outcomes. ( Awad, S; Lobo, DN, 2012) |
| "Carnitine deficiency and impaired glucose tolerance (IGT) exacerbate liver steatosis." | 4.12 | High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models. ( Matsuura, T; Mekada, K; Nakamura, SI; Ozaki, K; Terayama, Y, 2022) |
| " This study tested whether loss of weight by liraglutide combined with decreasing acylcarnitines (AcylCNs) represent an effective strategy to improve insulin sensitivity in obese insulin-resistant females." | 4.02 | Liraglutide treatment and acylcarnitine profiles in Egyptian obese insulin-resistant females. ( Ebied, SA; El-Kotishy, SM; Hussein, NA; Nour, HA; Salem, TM; Zaki, UK, 2021) |
| "To address this gap, this study evaluated insulin sensitivity and subcellular localization of intramuscular triacylglycerol, diacylglycerol, and sphingolipids as well as muscle acylcarnitines and serum lipidomics in people with obesity." | 4.02 | Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution. ( Bergman, BC; Broussard, JL; Brozinick, JT; Bui, HH; D'Alessandro, A; Harrison, K; Macias, E; Milligan, P; Nemkov, T; Newsom, SA; Perreault, L; Roth, KD, 2021) |
| " As increased levels of long-chain acylcarnitines have been linked to insulin resistance, we investigated the effects of long-chain acylcarnitines on key components of the insulin signalling pathway." | 4.02 | Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism. ( Dambrova, M; Grandane, A; Katkevics, M; Liepinsh, E; Makrecka-Kuka, M; Sevostjanovs, E; Videja, M; Vilks, K, 2021) |
| "Godex improved insulin resistance and steatosis by regulating carnitine acetyltransferase in liver in high-fat diet-fed mice." | 4.02 | Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway. ( Hong, JH; Lee, MK, 2021) |
| " Notably, genetic deletion of gpr27 elevated medium-chain acylcarnitines, in particular C6-hexanoylcarnitine, C8-octanoylcarnitine, C9-nonanoylcarnitine, and C10-decanoylcarnitine, lipid species known to be associated with insulin resistance in humans." | 3.96 | Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish. ( Chen, ZZ; Gerszten, RE; Kelley, ML; Li, Z; Ma, J; Nath, AK; Peterson, RT; Vitery, MDC; Yeh, JJ, 2020) |
| "In boys, the BCAA score corresponded with decreasing C-peptide, C-peptide-based insulin resistance (CP-IR), total cholesterol (TC), and low-density-lipoprotein cholesterol (LDL)." | 3.91 | Metabolomic profiles and development of metabolic risk during the pubertal transition: a prospective study in the ELEMENT Project. ( Cantoral, A; Perng, W; Peterson, KE; Song, PXK; Tang, L; Tellez-Rojo, MM, 2019) |
| " IR in adults with obesity and diabetes is associated with changes in amino acid, free fatty acid (FFA), and mitochondrial acylcarnitine (AC) metabolism." | 3.91 | Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome. ( Bergman, BC; Carreau, AM; Cree-Green, M; Garcia-Reyes, Y; Nadeau, KJ; Pyle, L; Rahat, H, 2019) |
| " Blood samples were taken after overnight fasting at baseline and three months into the study to assess the levels of fasting glucose, insulin, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), free testosterone, dehydroepiandrosterone (DHEA), and the insulin resistance index (HOMA-IR)." | 3.91 | Effects of L-carnitine on Polycystic Ovary Syndrome. ( Gachkar, L; Hoseini, S; Moghaddam, PB; Nazari, L; Salehpour, S, 2019) |
| "We conclude that the removal of dysfunctional mitochondria by induction of autophagy through PPARγ may be a novel mechanism by which carnitine improves insulin resistance and mitochondrial dysfunction in obesity." | 3.88 | Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction. ( Choi, JW; Chung, SS; Jang, HC; Jung, HS; Ohn, JH; Park, KS; Park, YJ, 2018) |
| " Plasma levels of glucose, insulin, malondialdehyde and antioxidants such as reduced glutathione, catalase and superoxide dismutase, haemoglobin A1c (HbA1c), insulin sensitivity index (ISI) as well as the contractile properties of the gastrocnemius muscle were measured." | 3.88 | Effect of L-carnitine on diabetes-induced changes of skeletal muscles in rats. ( Abbas, AM; Elserougy, HG; Safwat, SM; Samir, SM, 2018) |
| "Targeted metabolomic assays of clinical metabolites, amino acids, and acylcarnitines were performed on fasting and 1-h postglucose serum samples from European ancestry, Afro-Caribbean, Thai, and Mexican American mothers (400 from each ancestry group) who participated in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study and underwent an oral glucose tolerance test at ∼28 weeks gestation." | 3.85 | Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups. ( Bain, JR; Ilkayeva, OR; Jacob, S; Lowe, LP; Lowe, WL; Metzger, BE; Muehlbauer, MJ; Newgard, CB; Nodzenski, M; Reisetter, AC; Scholtens, DM; Stevens, RD, 2017) |
| "Acylcarnitines (ACs) have been shown to have a potential to activate pro-inflammatory signaling pathways and to foster the development of insulin resistance." | 3.85 | Profiling of Acylcarnitines in First Episode Psychosis before and after Antipsychotic Treatment. ( Balõtšev, R; Haring, L; Innos, J; Koido, K; Kriisa, K; Leppik, L; Ottas, A; Soomets, U; Vasar, E; Volke, V; Zilmer, M, 2017) |
| "Circulating acyl-carnitines (acyl-CNTs) are associated with insulin resistance (IR) and type 2 diabetes (T2D) in both rodents and humans." | 3.85 | Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women. ( Abate, N; Asghar, R; Brasier, AR; Camacho-Hughes, M; Chondronikola, M; Dillon, EL; Durham, WJ; Porter, C; Sheffield-Moore, M; Sidossis, L; Tuvdendorj, D; Volpi, E; Wu, Z; Zhang, X; Zhao, Y, 2017) |
| "What is the central question of this study? Does improved metabolic health and insulin sensitivity following a weight-loss and fitness intervention in sedentary, obese women alter exercise-associated fuel metabolism and incomplete mitochondrial fatty acid oxidation (FAO), as tracked by blood acylcarnitine patterns? What is the main finding and its importance? Despite improved fitness and blood sugar control, indices of incomplete mitochondrial FAO increased in a similar manner in response to a fixed load acute exercise bout; this indicates that intramitochondrial muscle FAO is inherently inefficient and is tethered directly to ATP turnover." | 3.85 | Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons. ( Adams, SH; Burnett, DJ; Campbell, C; Casazza, GA; Chandler, CJ; Fernandez, JR; Fiehn, O; Garvey, WT; Harper, ME; Hoppel, CL; Hughen, RW; Hunter, GR; Keim, NL; Light, AR; Newman, JW; Souza, EC; Zhang, J, 2017) |
| "The important pathological consequences of insulin resistance arise from the detrimental effects of accumulated long-chain fatty acids and their respective acylcarnitines." | 3.83 | Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. ( Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Svalbe, B; Volska, K, 2016) |
| " Clinical improvements in insulin sensitivity, energy metabolism, and inflammation were related to metabolic alterations of free fatty acids (FFAs), acylcarnitines, amino acids, bile acids, and lipids species." | 3.83 | Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry. ( Bao, Y; Gao, P; Hong, CS; Jia, W; Luo, P; Tu, Y; Wei, L; Xu, G; Yin, P; Yu, H; Zhang, P; Zhao, X; Zhuang, Z, 2016) |
| " We hypothesized that increasing free carnitine levels by administration of the carnitine precursor γ-butyrobetaine (γBB) could facilitate FAO, thereby improving insulin sensitivity." | 3.83 | The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice. ( Hollak, CE; Houten, SM; Houtkooper, RH; Schooneman, MG; Soeters, MR; Vaz, FM; Wanders, RJ, 2016) |
| "The purpose of this study was to determine if plasma acylcarnitine (AC) profiling is altered under hyperinsulinemic conditions as part of the aging process." | 3.83 | Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction. ( Consitt, LA; Houmard, JA; Koves, TR; Muoio, DM; Nakazawa, M; Newton, CA, 2016) |
| "Insulin resistance may be linked to incomplete fatty acid β-oxidation and the subsequent increase in acylcarnitine species in different tissues including skeletal muscle." | 3.81 | Acylcarnitines: potential implications for skeletal muscle insulin resistance. ( Adams, SH; Aguer, C; Dent, R; Harper, ME; Hwang, DH; Knotts, TA; McCoin, CS; McPherson, R; Ono-Moore, K; Thrush, AB, 2015) |
| "The aim of this study was to estimate the effect of carnitine supplementation on lipid disorders and peripheral tissue insulin sensitivity in a non-obese animal model of insulin resistance, the hereditary hypertriglyceridemic (HHTg) rat." | 3.81 | Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. ( Cahova, M; Chrastina, P; Drahota, Z; Hansikova, H; Kazdova, L; Malinska, H; Oliyarnyk, O; Palenickova, E; Papackova, Z; Skop, V; Spacilova, J; Trnovska, J, 2015) |
| "Acylcarnitine accumulation in skeletal muscle and plasma has been observed in numerous models of mitochondrial lipid overload and insulin resistance." | 3.80 | Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation. ( Barrett, DA; Cooper, S; Mansell, P; Mendis, B; Ortori, CA; Shannon, CE; Stephens, FB; Tsintzas, K, 2014) |
| "Acylcarnitines have been linked to obesity-induced insulin resistance." | 3.80 | Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism. ( Achterkamp, N; Argmann, CA; Houten, SM; Schooneman, MG; Soeters, MR, 2014) |
| "The objectives of the present study were to determine the effects of long-term oral administration of L-carnitine on insulin sensitivity, glucose disposal, plasma leptin concentrations and acylcarnitine spectrum both in plasma and urine." | 3.80 | The effect of long-term oral L-carnitine administration on insulin sensitivity, glucose disposal, plasma concentrations of leptin and acylcarnitines, and urinary acylcarnitine excretion in warmblood horses. ( Buyse, J; de Graaf-Roelfsema, E; de Sain-van der Velden, MG; Janssens, GP; Kranenburg, LC; van den Broek, J; van der Kolk, JH; Westermann, CM, 2014) |
| "To compare the effects of combined and individual supplementation of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats." | 3.79 | Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats. ( Ahmad, T; Anwar, MK; Hussain, MM; Khan, MA, 2013) |
| "Accumulation of triacylglycerols (TAGs) and acylcarnitines in skeletal muscle upon high-fat (HF) feeding is the resultant of fatty acid uptake and oxidation and is associated with insulin resistance." | 3.77 | The effects of long- or medium-chain fat diets on glucose tolerance and myocellular content of lipid intermediates in rats. ( Boon, W; De Vogel-van den Bosch, J; Hesselink, MK; Hoeks, J; Houten, SM; Kersten, S; Schaart, G; Schrauwen, P; Timmers, S; Van Beurden, D; van Dijk, PJ; Voshol, PJ; Wanders, RJ, 2011) |
| "Decreased total L-carnitine levels may be associated with hyperandrogenism and/or insulin resistance in non-obese women with PCOS." | 3.74 | Serum total L-carnitine levels in non-obese women with polycystic ovary syndrome. ( Fenkci, SM; Fenkci, V; Karagenc, N; Oztekin, O; Rota, S, 2008) |
| "Previous studies have underlined the importance of the carnitine shuttle system and its dysfunction both in normal pregnancy and in type 1 and 2 diabetes." | 3.73 | Gestational diabetes exhibits lack of carnitine deficiency despite relatively low carnitine levels and alterations in ketogenesis. ( Anagnou, NP; Anogianaki, N; Bikouvarakis, S; Evangeliou, A; Koumantakis, E; Maropoulos, G; Pappa, KI; Salamalekis, E, 2005) |
| " We investigated the effect of dietary genistein (the principal soy isoflavone) alone and combined with L-carnitine to evaluate possible synergistic effects on the intentionally induced prediabetic state characterized by insulin resistance and obesity in C57Bl/6J mice fed a high-fat diet (HD)." | 3.73 | Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. ( Cha, YS; Lee, SJ; Park, HW; Yang, JY, 2006) |
| " In patients with NASH and control subjects, we measured free carnitine, short-chain acylcarnitine (SCAC) and long-chain acylcarnitine (LCAC) esters, carnitine palmitoyltransferase (CPT) activity, and MRC enzyme activity in liver tissue as well as serum concentration of tumor necrosis factor alpha (TNF-alpha), homeostatic metabolic assessment of insulin resistance (HOMA(IR)), and body mass index (BMI)." | 3.72 | Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. ( Arenas, J; Castellano, G; Colina, F; Del Hoyo, P; Martín, A; Martín, MA; Pérez-Carreras, M; Rubio, JC; Solis-Herruzo, JA, 2003) |
| "Spillover of AC occurs in type 2 diabetes but is not fully established in FH+." | 2.87 | Plasma Palmitoyl-Carnitine (AC16:0) Is a Marker of Increased Postprandial Nonesterified Incomplete Fatty Acid Oxidation Rate in Adults With Type 2 Diabetes. ( Bouchouirab, FZ; Carpentier, AC; Dubé, J; Fortin, M; Noll, C, 2018) |
| "Overweight patients with hyperlipidemia (serum triglyceride ≥ 1." | 2.80 | Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. ( Du, S; Jiang, S; Li, Y; Na, L; Niu, Y; Sun, C; Zhang, Q; Zhang, W, 2015) |
| "A Tolbutamide test was done and blood sugar (BS), serum C-peptide (CP) were measured at 0, 20 and 60 minutes, as well as the plasma L-carnitine level before and after treatment." | 2.71 | L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response. ( Assenova, B; Borissova, AM; Kirilov, G; Krivoshiev, S; Tchetirska, M; Vazelov, E, 2003) |
| "L-carnitine has also been shown to improve insulin sensitivity and elevate pyruvate dehydrogenase (PDH) flux." | 2.66 | The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD). ( Hodson, L; Neubauer, S; Pavlides, M; Savic, D, 2020) |
| "Type 2 diabetes is a highly prevalent chronic metabolic disorder characterized by hyperglycemia and associated with several complications such as retinopathy, hyperlipidemia and polyneuropathy." | 2.58 | Role of carnitine and its derivatives in the development and management of type 2 diabetes. ( Bene, J; Hadzsiev, K; Melegh, B, 2018) |
| "Type 2 diabetes mellitus is an independent risk factor for the development of cardiovascular disease." | 2.47 | Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders. ( Alvarez de Sotomayor, M; Herrera, MD; Justo, ML; Mingorance, C; Rodríguez-Rodríguez, R, 2011) |
| "Carnitine is a trimethylamine molecule that plays a unique role in cell energy metabolism." | 2.42 | The carnitine system and body composition. ( Benatti, P; Calvani, M; D'Iddio, S; Nicolai, R; Reda, E, 2003) |
| "Carnitine is a small water-soluble molecule that is present in almost all animal species." | 2.42 | Carnitine system in uremic patients: molecular and clinical aspects. ( Bellinghieri, G; Benatti, P; Calvani, M; Monardo, P; Peluso, G; Santoro, D; Savica, V, 2004) |
| "2 mg/kg/min, without a significant dose-response effect." | 2.42 | Carnitine in type 2 diabetes. ( Mingrone, G, 2004) |
| "In participants with type 2 diabetes, after Bonferroni correction and rigorous adjustment, SDNN was inversely associated with higher levels of diacyl-phosphatidylcholine (PCaa) C32:0, PCaa C34:1, acyl-alkyl-phosphatidylcholine (PCae) C36:0, SM C16:0 and SM C16:1." | 1.62 | Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes. ( Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D, 2021) |
| "l-Carnitine is an antioxidant, affecting mitochondria and cellular energetics; however, little is known about its effects in hyperuricemic states." | 1.51 | Possible role of l-carnitine in improvement of metabolic and hepatic changes in hyperuricemic and hyperuricemic-Fructose-supplemented rats. ( Ahmed, MA; El-Kafoury, BMA; ElKady, AH; Hammouda, GA; Lasheen, NN, 2019) |
| "Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood." | 1.48 | Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance. ( Ärnlöv, J; Berne, C; Broeckling, CD; Castillejo-Lopez, C; Cook, NL; Fall, T; Ganna, A; Giedraitis, V; Hetty, S; Ingelsson, E; Lind, L; Nowak, C; Prenni, JE; Salihovic, S; Shen, X; Sundström, J, 2018) |
| "We have previously demonstrated that neuropathic pain after nerve damage is exacerbated in autophagy-defective heterozygous Ambra1 mice." | 1.48 | Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice. ( Ciavardelli, D; Coccurello, R; De Angelis, F; Giacovazzo, G; Magnaghi, V; Marinelli, S; Nazio, F; Procacci, P; Rossi, C; Vacca, V, 2018) |
| "Acylcarnitine accumulation has been linked to perturbations in energy metabolism pathways." | 1.46 | Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice. ( Antone, U; Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Lola, D; Loza, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Vilks, K; Vilskersts, R; Volska, K, 2017) |
| "Fasting insulin sensitivity was measured using homeostatic model assessment 2 (HOMA2), and adipose tissue was measured using dual-energy x-ray absorptiometry (DEXA)." | 1.43 | Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy. ( Culver, J; Jenkins, CA; Koethe, JR; Petucci, C; Shepherd, BE; Sterling, TR, 2016) |
| "Obesity is associated with insulin resistance and impaired glucose tolerance, which represent characteristic features of the metabolic syndrome." | 1.43 | Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice. ( Bardova, K; Gardlo, A; Hansikova, J; Horakova, O; Kopecky, J; Kuda, O; Rombaldova, M; Rossmeisl, M, 2016) |
| "Although evidence that type 2 diabetes mellitus (T2DM) is accompanied by mitochondrial dysfunction in skeletal muscle has been accumulating, a causal link between mitochondrial dysfunction and the pathogenesis of the disease remains unclear." | 1.40 | Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat. ( Affolter, A; Clanachan, AS; Hersberger, M; Lemieux, H; Lou, PH; Lucchinetti, E; Warren, BE; Zaugg, M; Zhang, L, 2014) |
| "Insulin sensitivity was determined with the isoglycaemic-hyperinsulinaemic clamp technique." | 1.37 | Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes. ( Andersen, JL; Dela, F; Hansen, CN; Helge, JW; Hey-Mogensen, M; Larsen, S; Madsbad, S; Stride, N; Worm, D, 2011) |
| "Type 2 familial partial lipodystrophy (FPLD) is an autosomal-dominant lamin A/C-related disease associated with exercise intolerance, muscular pain, and insulin resistance." | 1.36 | LMNA mutations, skeletal muscle lipid metabolism, and insulin resistance. ( Adams, F; Boschmann, M; Dobberstein, K; Engeli, S; Gorzelniak, K; Jordan, J; Krüger, A; Luedtke, A; Luft, FC; Mähler, A; Moro, C; Rahn, G; Schmidt, HH; Schmidt, S; Smith, SR; Spuler, S, 2010) |
| "Acylcarnitines have been suggested to play a role in insulin resistance, as well as other long-chain fatty acid metabolites." | 1.35 | Muscle acylcarnitines during short-term fasting in lean healthy men. ( Ackermans, MT; Duran, M; Fliers, E; Houten, SM; Sauerwein, HP; Serlie, MJ; Soeters, MR; Wanders, RJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.67) | 18.2507 |
| 2000's | 25 (16.67) | 29.6817 |
| 2010's | 104 (69.33) | 24.3611 |
| 2020's | 20 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sangouni, AA | 1 |
| Pakravanfar, F | 1 |
| Ghadiri-Anari, A | 1 |
| Nadjarzadeh, A | 1 |
| Fallahzadeh, H | 1 |
| Hosseinzadeh, M | 1 |
| Terayama, Y | 1 |
| Nakamura, SI | 1 |
| Mekada, K | 1 |
| Matsuura, T | 1 |
| Ozaki, K | 1 |
| Dambrova, M | 4 |
| Makrecka-Kuka, M | 4 |
| Kuka, J | 3 |
| Vilskersts, R | 2 |
| Nordberg, D | 1 |
| Attwood, MM | 1 |
| Smesny, S | 1 |
| Sen, ZD | 1 |
| Guo, AC | 1 |
| Oler, E | 1 |
| Tian, S | 1 |
| Zheng, J | 1 |
| Wishart, DS | 1 |
| Liepinsh, E | 4 |
| Schiöth, HB | 1 |
| Gong, Y | 1 |
| Jiang, T | 1 |
| He, H | 1 |
| Wang, Y | 1 |
| Wu, GL | 1 |
| Shi, Y | 1 |
| Cai, Q | 1 |
| Xiong, CL | 1 |
| Shen, R | 1 |
| Li, J | 1 |
| Li, Y | 3 |
| Xie, Y | 1 |
| Qiu, C | 1 |
| Yu, B | 1 |
| Yang, F | 1 |
| Cheng, Y | 1 |
| Zhong, W | 1 |
| Yuan, J | 1 |
| Lowry, JE | 1 |
| Tumurbaatar, B | 1 |
| D'Agostino, C | 1 |
| Main, E | 1 |
| Wright, TJ | 1 |
| Dillon, EL | 2 |
| Saito, TB | 1 |
| Porter, C | 2 |
| Andersen, CR | 1 |
| Brining, DL | 1 |
| Endsley, JJ | 1 |
| Sheffield-Moore, M | 2 |
| Volpi, E | 2 |
| Fang, R | 1 |
| Abate, N | 2 |
| Tuvdendorj, DR | 1 |
| El-Kafoury, BMA | 1 |
| Ahmed, MA | 1 |
| Hammouda, GA | 1 |
| ElKady, AH | 1 |
| Lasheen, NN | 1 |
| Sepandar, F | 1 |
| Daneshpazhooh, M | 1 |
| Djalali, M | 1 |
| Mohammadi, H | 1 |
| Yaghubi, E | 1 |
| Fakhri, Z | 1 |
| Tavakoli, H | 1 |
| Ghaedi, E | 1 |
| Keshavarz, A | 1 |
| Zarei, M | 1 |
| Shahrbaf, MA | 1 |
| Ghandi, N | 1 |
| Darand, M | 1 |
| Javanbakht, MH | 1 |
| Nath, AK | 1 |
| Ma, J | 1 |
| Chen, ZZ | 1 |
| Li, Z | 1 |
| Vitery, MDC | 1 |
| Kelley, ML | 1 |
| Peterson, RT | 1 |
| Gerszten, RE | 1 |
| Yeh, JJ | 1 |
| McFadden, JW | 2 |
| Molsberry, S | 1 |
| Bjornevik, K | 1 |
| Hughes, KC | 1 |
| Zhang, ZJ | 1 |
| Jeanfavre, S | 1 |
| Clish, C | 1 |
| Healy, B | 1 |
| Schwarzschild, M | 1 |
| Ascherio, A | 1 |
| Herzog, K | 1 |
| Berggren, J | 1 |
| Al Majdoub, M | 1 |
| Balderas Arroyo, C | 1 |
| Lindqvist, A | 1 |
| Hedenbro, J | 1 |
| Groop, L | 1 |
| Wierup, N | 1 |
| Spégel, P | 2 |
| Savic, D | 1 |
| Hodson, L | 1 |
| Neubauer, S | 1 |
| Pavlides, M | 1 |
| Bruls, YMH | 1 |
| Op den Kamp, YJM | 1 |
| Phielix, E | 1 |
| Lindeboom, L | 1 |
| Havekes, B | 1 |
| Schaart, G | 2 |
| Moonen-Kornips, E | 1 |
| Wildberger, JE | 1 |
| Hesselink, MKC | 1 |
| Schrauwen, P | 3 |
| Schrauwen-Hinderling, VB | 1 |
| Ziegler, D | 1 |
| Strom, A | 1 |
| Straßburger, K | 1 |
| Knebel, B | 1 |
| Bönhof, GJ | 1 |
| Kotzka, J | 1 |
| Szendroedi, J | 1 |
| Roden, M | 1 |
| Hussein, NA | 1 |
| Ebied, SA | 1 |
| Nour, HA | 1 |
| Zaki, UK | 1 |
| El-Kotishy, SM | 1 |
| Salem, TM | 1 |
| Pereyra, AS | 1 |
| Rajan, A | 1 |
| Ferreira, CR | 1 |
| Ellis, JM | 1 |
| Poulos, JE | 1 |
| Kalogerinis, PT | 1 |
| Milanov, V | 1 |
| Kalogerinis, CT | 1 |
| Poulos, EJ | 1 |
| Broussard, JL | 1 |
| Perreault, L | 1 |
| Macias, E | 1 |
| Newsom, SA | 2 |
| Harrison, K | 1 |
| Bui, HH | 1 |
| Milligan, P | 1 |
| Roth, KD | 1 |
| Nemkov, T | 1 |
| D'Alessandro, A | 1 |
| Brozinick, JT | 1 |
| Bergman, BC | 2 |
| Owei, I | 1 |
| Umekwe, N | 1 |
| Stentz, F | 1 |
| Wan, J | 1 |
| Dagogo-Jack, S | 1 |
| Vilks, K | 2 |
| Videja, M | 1 |
| Katkevics, M | 1 |
| Sevostjanovs, E | 3 |
| Grandane, A | 1 |
| Hong, JH | 1 |
| Lee, MK | 1 |
| Zhang, N | 1 |
| Valentine, JM | 1 |
| Zhou, Y | 1 |
| Li, ME | 1 |
| Zhang, Y | 1 |
| Bhattacharya, A | 1 |
| Walsh, ME | 1 |
| Fischer, KE | 1 |
| Austad, SN | 1 |
| Osmulski, P | 1 |
| Gaczynska, M | 1 |
| Shoelson, SE | 1 |
| Van Remmen, H | 1 |
| Chen, HI | 1 |
| Chen, Y | 1 |
| Liang, H | 1 |
| Musi, N | 1 |
| Jacob, S | 1 |
| Nodzenski, M | 1 |
| Reisetter, AC | 1 |
| Bain, JR | 4 |
| Muehlbauer, MJ | 3 |
| Stevens, RD | 6 |
| Ilkayeva, OR | 3 |
| Lowe, LP | 1 |
| Metzger, BE | 1 |
| Newgard, CB | 6 |
| Scholtens, DM | 1 |
| Lowe, WL | 1 |
| Makarova, E | 2 |
| Volska, K | 2 |
| Antone, U | 1 |
| Lola, D | 1 |
| Loza, E | 1 |
| Grinberga, S | 2 |
| Kriisa, K | 1 |
| Leppik, L | 1 |
| Balõtšev, R | 1 |
| Ottas, A | 1 |
| Soomets, U | 1 |
| Koido, K | 1 |
| Volke, V | 1 |
| Innos, J | 1 |
| Haring, L | 1 |
| Vasar, E | 1 |
| Zilmer, M | 1 |
| Choi, JW | 1 |
| Ohn, JH | 1 |
| Jung, HS | 1 |
| Park, YJ | 1 |
| Jang, HC | 2 |
| Chung, SS | 1 |
| Park, KS | 2 |
| Samir, SM | 1 |
| Abbas, AM | 1 |
| Safwat, SM | 1 |
| Elserougy, HG | 1 |
| Rico, JE | 1 |
| Zang, Y | 1 |
| Haughey, NJ | 1 |
| Rius, AG | 1 |
| Bouchouirab, FZ | 1 |
| Fortin, M | 1 |
| Noll, C | 1 |
| Dubé, J | 1 |
| Carpentier, AC | 2 |
| Rossi, A | 1 |
| Ruoppolo, M | 2 |
| Formisano, P | 1 |
| Villani, G | 1 |
| Albano, L | 1 |
| Gallo, G | 1 |
| Crisci, D | 1 |
| Moccia, A | 1 |
| Parenti, G | 1 |
| Strisciuglio, P | 1 |
| Melis, D | 1 |
| Bene, J | 1 |
| Hadzsiev, K | 1 |
| Melegh, B | 1 |
| Metrustry, SJ | 1 |
| Karhunen, V | 1 |
| Edwards, MH | 1 |
| Menni, C | 1 |
| Geisendorfer, T | 1 |
| Huber, A | 1 |
| Reichel, C | 1 |
| Dennison, EM | 1 |
| Cooper, C | 1 |
| Spector, T | 1 |
| Jarvelin, MR | 1 |
| Valdes, AM | 1 |
| Safai, N | 1 |
| Suvitaival, T | 1 |
| Ali, A | 1 |
| Al-Majdoub, M | 1 |
| Carstensen, B | 1 |
| Vestergaard, H | 1 |
| Ridderstråle, M | 1 |
| Dasari, S | 1 |
| Ehrlicher, SE | 1 |
| Stierwalt, HD | 1 |
| Robinson, MM | 1 |
| Heianza, Y | 1 |
| Sun, D | 1 |
| Li, X | 1 |
| DiDonato, JA | 1 |
| Bray, GA | 1 |
| Sacks, FM | 1 |
| Qi, L | 1 |
| Nowak, C | 1 |
| Hetty, S | 1 |
| Salihovic, S | 1 |
| Castillejo-Lopez, C | 1 |
| Ganna, A | 1 |
| Cook, NL | 1 |
| Broeckling, CD | 1 |
| Prenni, JE | 1 |
| Shen, X | 1 |
| Giedraitis, V | 1 |
| Ärnlöv, J | 1 |
| Lind, L | 1 |
| Berne, C | 1 |
| Sundström, J | 1 |
| Fall, T | 1 |
| Ingelsson, E | 1 |
| Zabielski, P | 2 |
| Daniluk, J | 1 |
| Hady, HR | 1 |
| Markowski, AR | 1 |
| Imierska, M | 1 |
| Górski, J | 1 |
| Blachnio-Zabielska, AU | 1 |
| Giacco, A | 1 |
| Delli Paoli, G | 1 |
| Senese, R | 1 |
| Cioffi, F | 1 |
| Silvestri, E | 1 |
| Moreno, M | 1 |
| Caterino, M | 1 |
| Costanzo, M | 1 |
| Lombardi, A | 1 |
| Goglia, F | 1 |
| Lanni, A | 1 |
| de Lange, P | 1 |
| Zayed, EA | 1 |
| AinShoka, AA | 1 |
| El Shazly, KA | 1 |
| Abd El Latif, HA | 1 |
| Perng, W | 1 |
| Tang, L | 1 |
| Song, PXK | 1 |
| Tellez-Rojo, MM | 1 |
| Cantoral, A | 1 |
| Peterson, KE | 1 |
| Coccurello, R | 1 |
| Nazio, F | 1 |
| Rossi, C | 2 |
| De Angelis, F | 1 |
| Vacca, V | 1 |
| Giacovazzo, G | 1 |
| Procacci, P | 1 |
| Magnaghi, V | 1 |
| Ciavardelli, D | 1 |
| Marinelli, S | 1 |
| Cree-Green, M | 1 |
| Carreau, AM | 1 |
| Rahat, H | 1 |
| Garcia-Reyes, Y | 1 |
| Pyle, L | 1 |
| Nadeau, KJ | 1 |
| El Sharkwy, I | 1 |
| Sharaf El-Din, M | 1 |
| Maleki, V | 1 |
| Jafari-Vayghan, H | 1 |
| Kashani, A | 1 |
| Moradi, F | 1 |
| Vajdi, M | 1 |
| Kheirouri, S | 1 |
| Alizadeh, M | 1 |
| Xu, X | 1 |
| Zhu, XP | 1 |
| Bai, JY | 1 |
| Xia, P | 1 |
| Lu, Y | 1 |
| Li, XY | 1 |
| Gao, X | 1 |
| Chacińska, M | 1 |
| Książek, M | 1 |
| Szałaj, P | 1 |
| Jarząbek, K | 1 |
| Kojta, I | 1 |
| Chabowski, A | 1 |
| Błachnio-Zabielska, AU | 1 |
| Diamanti, K | 1 |
| Cavalli, M | 1 |
| Pan, G | 1 |
| Pereira, MJ | 1 |
| Kumar, C | 1 |
| Skrtic, S | 1 |
| Grabherr, M | 1 |
| Risérus, U | 1 |
| Eriksson, JW | 1 |
| Komorowski, J | 1 |
| Wadelius, C | 1 |
| El Sharkwy, IA | 1 |
| Abd El Aziz, WM | 1 |
| Salehpour, S | 1 |
| Nazari, L | 1 |
| Hoseini, S | 1 |
| Moghaddam, PB | 1 |
| Gachkar, L | 1 |
| St-Onge, M | 1 |
| Ajmo, I | 1 |
| Poirier, D | 1 |
| Laliberté, M | 1 |
| Bonomini, M | 1 |
| Di Liberato, L | 1 |
| Del Rosso, G | 1 |
| Stingone, A | 1 |
| Marinangeli, G | 1 |
| Consoli, A | 1 |
| Bertoli, S | 1 |
| De Vecchi, A | 1 |
| Bosi, E | 1 |
| Russo, R | 1 |
| Corciulo, R | 1 |
| Gesualdo, L | 1 |
| Giorgino, F | 1 |
| Cerasoli, P | 1 |
| Di Castelnuovo, A | 1 |
| Monaco, MP | 1 |
| Shockley, T | 1 |
| Arduini, A | 5 |
| Kanaley, JA | 1 |
| Shadid, S | 1 |
| Sheehan, MT | 1 |
| Guo, Z | 1 |
| Jensen, MD | 1 |
| Sato, C | 1 |
| Saito, T | 1 |
| Misawa, K | 1 |
| Katsumi, T | 1 |
| Tomita, K | 1 |
| Ishii, R | 1 |
| Haga, H | 1 |
| Okumoto, K | 1 |
| Nishise, Y | 1 |
| Watanabe, H | 1 |
| Ueno, Y | 1 |
| Kawata, S | 1 |
| Anwar, MK | 1 |
| Hussain, MM | 1 |
| Khan, MA | 1 |
| Ahmad, T | 1 |
| Ussher, JR | 1 |
| Lopaschuk, GD | 3 |
| Warren, BE | 1 |
| Lou, PH | 1 |
| Lucchinetti, E | 1 |
| Zhang, L | 1 |
| Clanachan, AS | 1 |
| Affolter, A | 1 |
| Hersberger, M | 1 |
| Zaugg, M | 1 |
| Lemieux, H | 1 |
| Stephens, FB | 1 |
| Mendis, B | 1 |
| Shannon, CE | 1 |
| Cooper, S | 1 |
| Ortori, CA | 1 |
| Barrett, DA | 1 |
| Mansell, P | 1 |
| Tsintzas, K | 1 |
| Hong, ES | 1 |
| Kim, EK | 1 |
| Kang, SM | 1 |
| Khang, AR | 1 |
| Choi, SH | 1 |
| Lim, S | 1 |
| Schooneman, MG | 4 |
| Achterkamp, N | 1 |
| Argmann, CA | 1 |
| Soeters, MR | 5 |
| Houten, SM | 7 |
| Kranenburg, LC | 1 |
| Westermann, CM | 1 |
| de Sain-van der Velden, MG | 1 |
| de Graaf-Roelfsema, E | 1 |
| Buyse, J | 1 |
| Janssens, GP | 1 |
| van den Broek, J | 1 |
| van der Kolk, JH | 1 |
| Aguer, C | 1 |
| McCoin, CS | 1 |
| Knotts, TA | 1 |
| Thrush, AB | 1 |
| Ono-Moore, K | 1 |
| McPherson, R | 1 |
| Dent, R | 1 |
| Hwang, DH | 1 |
| Adams, SH | 2 |
| Harper, ME | 2 |
| Rahimi, Y | 1 |
| Camporez, JP | 1 |
| Petersen, MC | 1 |
| Pesta, D | 1 |
| Perry, RJ | 1 |
| Jurczak, MJ | 1 |
| Cline, GW | 3 |
| Shulman, GI | 3 |
| Henagan, TM | 1 |
| Stefanska, B | 1 |
| Fang, Z | 1 |
| Navard, AM | 1 |
| Ye, J | 1 |
| Lenard, NR | 1 |
| Devarshi, PP | 1 |
| Cahova, M | 1 |
| Chrastina, P | 1 |
| Hansikova, H | 1 |
| Drahota, Z | 1 |
| Trnovska, J | 1 |
| Skop, V | 1 |
| Spacilova, J | 1 |
| Malinska, H | 1 |
| Oliyarnyk, O | 1 |
| Papackova, Z | 1 |
| Palenickova, E | 1 |
| Kazdova, L | 1 |
| Na, L | 1 |
| Zhang, Q | 1 |
| Jiang, S | 1 |
| Du, S | 1 |
| Zhang, W | 1 |
| Sun, C | 2 |
| Niu, Y | 1 |
| Avalos-Soriano, A | 2 |
| De la Cruz-Cordero, R | 2 |
| López-Martínez, FJ | 1 |
| Rosado, JL | 1 |
| Duarte-Vázquez, MÁ | 2 |
| Garcia-Gasca, T | 1 |
| Mook-Kanamori, DO | 2 |
| de Mutsert, R | 1 |
| Rensen, PC | 2 |
| Prehn, C | 2 |
| Adamski, J | 2 |
| den Heijer, M | 1 |
| le Cessie, S | 1 |
| Suhre, K | 1 |
| Rosendaal, FR | 1 |
| van Dijk, KW | 2 |
| van den Berg, R | 1 |
| Donga, E | 1 |
| van Dijk, M | 1 |
| van Dijk, JG | 1 |
| Lammers, GJ | 1 |
| van Kralingen, KW | 1 |
| Romijn, JA | 1 |
| Corssmit, EP | 1 |
| Biermasz, NR | 1 |
| Ruiz, M | 1 |
| Coderre, L | 1 |
| Lachance, D | 1 |
| Houde, V | 1 |
| Martel, C | 1 |
| Thompson Legault, J | 1 |
| Gillis, MA | 1 |
| Bouchard, B | 1 |
| Daneault, C | 1 |
| Gaestel, M | 1 |
| Allen, BG | 1 |
| Des Rosiers, C | 1 |
| Svalbe, B | 1 |
| Samimi, M | 1 |
| Jamilian, M | 1 |
| Ebrahimi, FA | 1 |
| Rahimi, M | 1 |
| Tajbakhsh, B | 1 |
| Asemi, Z | 1 |
| Chen, YX | 1 |
| Zhang, XJ | 1 |
| Huang, J | 1 |
| Zhou, SJ | 1 |
| Liu, F | 1 |
| Jiang, LL | 1 |
| Chen, M | 1 |
| Wan, JB | 1 |
| Yang, DZ | 1 |
| Patterson, RE | 1 |
| Kalavalapalli, S | 1 |
| Williams, CM | 1 |
| Nautiyal, M | 1 |
| Mathew, JT | 1 |
| Martinez, J | 1 |
| Reinhard, MK | 1 |
| McDougall, DJ | 1 |
| Rocca, JR | 1 |
| Yost, RA | 1 |
| Cusi, K | 1 |
| Garrett, TJ | 1 |
| Sunny, NE | 1 |
| Pallares-Méndez, R | 1 |
| Aguilar-Salinas, CA | 1 |
| Cruz-Bautista, I | 1 |
| Del Bosque-Plata, L | 1 |
| Luo, P | 1 |
| Yu, H | 1 |
| Zhao, X | 2 |
| Bao, Y | 1 |
| Hong, CS | 1 |
| Zhang, P | 1 |
| Tu, Y | 1 |
| Yin, P | 1 |
| Gao, P | 1 |
| Wei, L | 1 |
| Zhuang, Z | 1 |
| Jia, W | 1 |
| Xu, G | 1 |
| Houtkooper, RH | 1 |
| Hollak, CE | 2 |
| Wanders, RJ | 4 |
| Vaz, FM | 2 |
| Koethe, JR | 1 |
| Jenkins, CA | 1 |
| Petucci, C | 1 |
| Culver, J | 1 |
| Shepherd, BE | 1 |
| Sterling, TR | 1 |
| Horakova, O | 1 |
| Hansikova, J | 1 |
| Bardova, K | 1 |
| Gardlo, A | 1 |
| Rombaldova, M | 1 |
| Kuda, O | 1 |
| Rossmeisl, M | 1 |
| Kopecky, J | 1 |
| Gopalan, V | 1 |
| Michael, N | 1 |
| Ishino, S | 1 |
| Lee, SS | 1 |
| Yang, AY | 1 |
| Bhanu Prakash, KN | 1 |
| Yaligar, J | 1 |
| Sadananthan, SA | 1 |
| Kaneko, M | 1 |
| Zhou, Z | 1 |
| Satomi, Y | 1 |
| Hirayama, M | 1 |
| Kamiguchi, H | 1 |
| Zhu, B | 1 |
| Horiguchi, T | 1 |
| Nishimoto, T | 1 |
| Velan, SS | 1 |
| Napolitano, A | 1 |
| Ambler, GK | 1 |
| Murgatroyd, PR | 1 |
| Miller, SR | 1 |
| Tan, CY | 1 |
| Virtue, S | 1 |
| Vidal-Puig, A | 1 |
| Nunez, DJ | 1 |
| Hesselink, MK | 2 |
| Schrauwen-Hinderling, V | 1 |
| Gang, X | 1 |
| Liu, Y | 1 |
| Han, Q | 1 |
| Wang, G | 1 |
| Chondronikola, M | 1 |
| Asghar, R | 1 |
| Zhang, X | 1 |
| Durham, WJ | 1 |
| Wu, Z | 1 |
| Camacho-Hughes, M | 1 |
| Zhao, Y | 1 |
| Brasier, AR | 1 |
| Sidossis, L | 1 |
| Tuvdendorj, D | 1 |
| Consitt, LA | 1 |
| Koves, TR | 3 |
| Muoio, DM | 7 |
| Nakazawa, M | 1 |
| Newton, CA | 1 |
| Houmard, JA | 3 |
| Ribel-Madsen, A | 1 |
| Ribel-Madsen, R | 1 |
| Brøns, C | 1 |
| Vaag, AA | 1 |
| Hellgren, LI | 1 |
| Capel, F | 1 |
| Cheraiti, N | 1 |
| Acquaviva, C | 1 |
| Hénique, C | 1 |
| Bertrand-Michel, J | 1 |
| Vianey-Saban, C | 1 |
| Prip-Buus, C | 1 |
| Morio, B | 1 |
| Zhang, J | 2 |
| Light, AR | 1 |
| Hoppel, CL | 1 |
| Campbell, C | 1 |
| Chandler, CJ | 1 |
| Burnett, DJ | 1 |
| Souza, EC | 1 |
| Casazza, GA | 1 |
| Hughen, RW | 1 |
| Keim, NL | 1 |
| Newman, JW | 1 |
| Hunter, GR | 1 |
| Fernandez, JR | 1 |
| Garvey, WT | 1 |
| Fiehn, O | 1 |
| Piemontese, L | 1 |
| Cerchia, C | 1 |
| Laghezza, A | 1 |
| Ziccardi, P | 1 |
| Sblano, S | 1 |
| Tortorella, P | 1 |
| Iacobazzi, V | 1 |
| Infantino, V | 1 |
| Convertini, P | 1 |
| Dal Piaz, F | 1 |
| Lupo, A | 1 |
| Colantuoni, V | 1 |
| Lavecchia, A | 1 |
| Loiodice, F | 1 |
| Celik, F | 1 |
| Kose, M | 1 |
| Yilmazer, M | 1 |
| Köken, GN | 1 |
| Arioz, DT | 1 |
| Kanat Pektas, M | 1 |
| Goldberg, EL | 1 |
| Dixit, VD | 1 |
| Sauerwein, HP | 1 |
| Duran, M | 1 |
| Ackermans, MT | 1 |
| Fliers, E | 1 |
| Serlie, MJ | 1 |
| Huffman, KM | 3 |
| Shah, SH | 1 |
| Muehlbauer, M | 1 |
| Slentz, CA | 1 |
| Tanner, CJ | 1 |
| Kuchibhatla, M | 1 |
| Kraus, WE | 4 |
| Mingorance, C | 3 |
| Gonzalez del Pozo, M | 1 |
| Dolores Herrera, M | 1 |
| Alvarez de Sotomayor, M | 2 |
| Mynatt, RL | 3 |
| Muniyappa, R | 1 |
| van den Broek, NM | 1 |
| Ciapaite, J | 1 |
| De Feyter, HM | 1 |
| Jeneson, JA | 1 |
| Nicolay, K | 1 |
| Prompers, JJ | 1 |
| Boschmann, M | 1 |
| Engeli, S | 1 |
| Moro, C | 1 |
| Luedtke, A | 1 |
| Adams, F | 1 |
| Gorzelniak, K | 1 |
| Rahn, G | 1 |
| Mähler, A | 1 |
| Dobberstein, K | 1 |
| Krüger, A | 1 |
| Schmidt, S | 1 |
| Spuler, S | 1 |
| Luft, FC | 1 |
| Smith, SR | 1 |
| Schmidt, HH | 1 |
| Jordan, J | 1 |
| Derosa, G | 4 |
| Maffioli, P | 4 |
| Salvadeo, SA | 2 |
| Ferrari, I | 4 |
| Gravina, A | 2 |
| Mereu, R | 2 |
| D'Angelo, A | 4 |
| Palumbo, I | 4 |
| Randazzo, S | 4 |
| Cicero, AF | 4 |
| Albaugh, VL | 1 |
| Vary, TC | 1 |
| Ilkayeva, O | 2 |
| Wenner, BR | 3 |
| Maresca, KP | 1 |
| Joyal, JL | 1 |
| Breazeale, S | 1 |
| Elich, TD | 1 |
| Lang, CH | 1 |
| Lynch, CJ | 1 |
| Kewalramani, G | 1 |
| Bilan, PJ | 1 |
| Klip, A | 1 |
| Lohninger, A | 1 |
| Radler, U | 1 |
| Jinniate, S | 1 |
| Lohninger, S | 1 |
| Karlic, H | 1 |
| Lechner, S | 1 |
| Mascher, D | 1 |
| Tammaa, A | 1 |
| Salzer, H | 1 |
| De Vogel-van den Bosch, J | 1 |
| Hoeks, J | 1 |
| Timmers, S | 1 |
| van Dijk, PJ | 1 |
| Boon, W | 1 |
| Van Beurden, D | 1 |
| Kersten, S | 1 |
| Voshol, PJ | 1 |
| Fogari, E | 2 |
| Redman, LM | 2 |
| Landerman, LR | 2 |
| Pieper, CF | 2 |
| Kraus, VB | 2 |
| Ravussin, E | 3 |
| Bhandari, S | 1 |
| Conti, R | 1 |
| Mannucci, E | 1 |
| Pessotto, P | 1 |
| Tassoni, E | 1 |
| Carminati, P | 2 |
| Giannessi, F | 1 |
| Larsen, S | 1 |
| Stride, N | 1 |
| Hey-Mogensen, M | 1 |
| Hansen, CN | 1 |
| Andersen, JL | 1 |
| Madsbad, S | 1 |
| Worm, D | 1 |
| Helge, JW | 1 |
| Dela, F | 1 |
| Rodríguez-Rodríguez, R | 2 |
| Justo, ML | 2 |
| Herrera, MD | 2 |
| Ceccarelli, SM | 1 |
| Chomienne, O | 1 |
| Gubler, M | 1 |
| de Sotomayor, MA | 1 |
| Kovalik, JP | 2 |
| Slentz, D | 1 |
| Nicoll, JB | 1 |
| Lea-Currie, YR | 1 |
| Everingham, K | 1 |
| Kien, CL | 1 |
| Buehrer, BM | 1 |
| Gómez-Solís, A | 1 |
| Reyes-Esparza, J | 1 |
| Rodríguez-Fragoso, L | 1 |
| Ringseis, R | 2 |
| Mooren, FC | 1 |
| Keller, J | 2 |
| Couturier, A | 1 |
| Wen, G | 1 |
| Hirche, F | 1 |
| Stangl, GI | 1 |
| Eder, K | 2 |
| Krüger, K | 1 |
| Awad, S | 2 |
| Lobo, DN | 2 |
| Magkos, F | 1 |
| Su, X | 1 |
| Bradley, D | 1 |
| Fabbrini, E | 1 |
| Conte, C | 1 |
| Eagon, JC | 1 |
| Varela, JE | 1 |
| Brunt, EM | 1 |
| Patterson, BW | 1 |
| Klein, S | 1 |
| Stephens, F | 1 |
| Shannon, C | 1 |
| Noland, RC | 1 |
| Seiler, SE | 1 |
| Davies, MN | 1 |
| DeBalsi, KL | 1 |
| Kheterpal, I | 1 |
| Covington, JD | 1 |
| Bajpeyi, S | 1 |
| Kraus, W | 1 |
| Titov, VN | 1 |
| Marcovina, SM | 1 |
| Sirtori, C | 1 |
| Peracino, A | 1 |
| Gheorghiade, M | 1 |
| Borum, P | 1 |
| Remuzzi, G | 1 |
| Ardehali, H | 1 |
| Brockman, DA | 1 |
| Chen, X | 1 |
| Gallaher, DD | 1 |
| Rondanelli, M | 1 |
| Opizzi, A | 1 |
| Perna, S | 1 |
| Faliva, M | 1 |
| Solerte, SB | 1 |
| Fioravanti, M | 1 |
| Klersy, C | 1 |
| Cava, E | 1 |
| Edda, C | 1 |
| Paolini, M | 1 |
| Maddalena, P | 1 |
| Scavone, L | 1 |
| Luciano, S | 1 |
| Ceccarelli, P | 1 |
| Paola, C | 1 |
| Castellaneta, E | 1 |
| Emanuela, C | 1 |
| Savina, C | 1 |
| Claudia, S | 1 |
| Donini, LM | 1 |
| Vazelov, E | 1 |
| Borissova, AM | 1 |
| Kirilov, G | 1 |
| Assenova, B | 1 |
| Tchetirska, M | 1 |
| Krivoshiev, S | 1 |
| Pérez-Carreras, M | 1 |
| Del Hoyo, P | 1 |
| Martín, MA | 1 |
| Rubio, JC | 1 |
| Martín, A | 1 |
| Castellano, G | 1 |
| Colina, F | 1 |
| Arenas, J | 1 |
| Solis-Herruzo, JA | 1 |
| Reda, E | 1 |
| D'Iddio, S | 1 |
| Nicolai, R | 1 |
| Benatti, P | 2 |
| Calvani, M | 2 |
| An, J | 1 |
| Shiota, M | 1 |
| Fujimoto, Y | 1 |
| Stevens, R | 1 |
| Millington, D | 1 |
| Dai, T | 1 |
| Abou-Rjaily, GA | 1 |
| Al-Share', QY | 1 |
| Yang, Y | 1 |
| Fernström, MA | 1 |
| Deangelis, AM | 1 |
| Lee, AD | 1 |
| Sweetman, L | 1 |
| Amato, A | 1 |
| Pasquali, M | 1 |
| Erickson, SK | 1 |
| Najjar, SM | 1 |
| Savica, V | 1 |
| Santoro, D | 1 |
| Monardo, P | 1 |
| Peluso, G | 1 |
| Bellinghieri, G | 1 |
| Mingrone, G | 2 |
| Pappa, KI | 1 |
| Anagnou, NP | 1 |
| Salamalekis, E | 1 |
| Bikouvarakis, S | 1 |
| Maropoulos, G | 1 |
| Anogianaki, N | 1 |
| Evangeliou, A | 1 |
| Koumantakis, E | 1 |
| Hammond, LE | 1 |
| Neschen, S | 1 |
| Romanelli, AJ | 1 |
| Coleman, RA | 1 |
| Lofgren, IE | 1 |
| Herron, KL | 1 |
| West, KL | 1 |
| Zern, TL | 1 |
| Brownbill, RA | 1 |
| Ilich, JZ | 1 |
| Koo, SI | 1 |
| Fernandez, ML | 1 |
| Yang, JY | 1 |
| Lee, SJ | 1 |
| Park, HW | 1 |
| Cha, YS | 1 |
| Takenaka, T | 1 |
| Kanno, Y | 1 |
| Ohno, Y | 1 |
| Suzuki, H | 1 |
| Power, RA | 1 |
| Hulver, MW | 1 |
| Zhang, JY | 1 |
| Dubois, J | 1 |
| Marchand, RM | 1 |
| Rajasekar, P | 3 |
| Anuradha, CV | 3 |
| Viswanathan, P | 1 |
| Balasaraswathi, K | 1 |
| Biolo, G | 1 |
| Stulle, M | 1 |
| Bianco, F | 1 |
| Mengozzi, G | 1 |
| Barazzoni, R | 1 |
| Vasile, A | 1 |
| Panzetta, G | 1 |
| Guarnieri, G | 1 |
| Fenkci, SM | 1 |
| Fenkci, V | 1 |
| Oztekin, O | 1 |
| Rota, S | 1 |
| Karagenc, N | 1 |
| Greco, AV | 1 |
| Capristo, E | 1 |
| Benedetti, G | 1 |
| Giancaterini, A | 1 |
| De Gaetano, A | 1 |
| Gasbarrini, G | 1 |
| Carr, A | 1 |
| Hudson, J | 1 |
| Chuah, J | 1 |
| Mallal, S | 1 |
| Law, M | 1 |
| Hoy, J | 1 |
| Doong, N | 1 |
| French, M | 1 |
| Smith, D | 1 |
| Cooper, DA | 1 |
| Ricciolini, R | 1 |
| Scalibastri, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)[NCT00072995] | 811 participants | Interventional | 2003-09-30 | Completed | |||
| N-Acetylcysteine Versus L-carnitine in Clomiphene Citrate Resistant Pcos Women. a Randomized Controlled Trial[NCT03164421] | Phase 2 | 164 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| The Effects of Acetyl L--Carnitine and Myo/Chiro-Inositol on Improving Ovulation, Pregnancy Rate, Ovarian Function and Perceived Stress Response in Patients With PCOS[NCT05767515] | 120 participants (Anticipated) | Interventional | 2023-04-15 | Not yet recruiting | |||
| Phase 2 Study of the Effect of a Peritoneal Dialysis Solution Containing Glucose (1.5%) and L-carnitine (0.1%) on Insulin Sensitivity in Patients on Continuous Ambulatory Peritoneal Dialysis[NCT00755456] | Phase 2 | 35 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| An Observational Cohort Study of Adipose Tissue and Immune Activation in Treated HIV Infection[NCT04439448] | 100 participants (Actual) | Observational | 2013-04-12 | Completed | |||
| Exercise-mediated Rescue of Mitochondrial Derangements Driving Insulin Resistance in Humans (EX-MITO-DYS-IR)[NCT06080594] | 15 participants (Anticipated) | Interventional | 2024-02-29 | Recruiting | |||
| Mitochondrial Derangements Driving Muscle Insulin Resistance in Humans[NCT06080581] | 30 participants (Anticipated) | Observational | 2023-10-20 | Recruiting | |||
| Bioenergetics and Metabolism in Pediatric Populations[NCT03323294] | 175 participants (Anticipated) | Observational | 2017-10-18 | Active, not recruiting | |||
| A Double-blind, Placebo-controlled, Crossover Study Examining the Acute Effects of Olanzapine on Plasma Leptin, Glucose Tolerance and Free Fatty Acids in Healthy Volunteers[NCT00741026] | 15 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Calorie Restriction Intervention Induces Enterotype-associated BMI Loss in Nonobese Individuals[NCT04044118] | 41 participants (Actual) | Interventional | 2017-04-01 | Completed | |||
| LIFESTAT - Living With Statins, a Cross Sectional Study on the Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being[NCT02250677] | 75 participants (Actual) | Observational | 2014-04-30 | Completed | |||
| Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being[NCT02796378] | Phase 4 | 30 participants (Anticipated) | Interventional | 2016-06-30 | Active, not recruiting | ||
| Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being[NCT02255682] | Phase 4 | 35 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Evaluation of a Bakery Product Enriched With Fibre and L-carnitine on Cardiovascular Risk Parameters in Patients With Metabolic Syndrome: a Randomized, Double-blind, Placebo-controlled Study[NCT02281253] | 54 participants (Actual) | Interventional | 2010-04-30 | Completed | |||
| Safety, Tolerance and Metabolic Effects of Using a Preoperative Oral Nutritional Supplement (PreOP Booster) in Gastrointestinal Surgery[NCT00662376] | 40 participants (Actual) | Interventional | 2008-04-30 | Completed | |||
| Metabolic Adaptations to Six Month Caloric Restriction[NCT00099151] | 48 participants | Interventional | 2002-03-31 | Completed | |||
| Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE)[NCT00427193] | 238 participants (Actual) | Interventional | 2007-05-31 | Completed | |||
| Effect of Dietary Protein and Energy Restriction in the Improvement of Insulin Resistance in Subjects With Obesity[NCT03627104] | 80 participants (Actual) | Interventional | 2018-09-03 | Completed | |||
| Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress Response in Patients With PCOS: A Double Blind Randomized Clinical Trial[NCT04113889] | Phase 2 | 147 participants (Actual) | Interventional | 2019-10-15 | Completed | ||
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
BMI (NCT00741026)
Timeframe: 3 Days
| Intervention | kg / m2 (Mean) |
|---|---|
| Placebo | 23.0 |
| Olanzapine | 23.0 |
Body Weight (NCT00741026)
Timeframe: 3 Days
| Intervention | kg (Mean) |
|---|---|
| Placebo | 68.2 |
| Olanzapine | 68.9 |
Diastolic Blood Pressure (NCT00741026)
Timeframe: 3 Days
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | 68.3 |
| Olanzapine | 69.5 |
HDL Cholesterol (NCT00741026)
Timeframe: 3 Days
| Intervention | mg/dl (Mean) |
|---|---|
| Placebo | 54.2 |
| Olanzapine | 48.9 |
Heart Rate (NCT00741026)
Timeframe: 3 Days
| Intervention | beats per minute (Mean) |
|---|---|
| Placebo | 69.9 |
| Olanzapine | 67.6 |
LDL Cholesterol (NCT00741026)
Timeframe: 3 Days
| Intervention | mg/dl (Mean) |
|---|---|
| Placebo | 82.7 |
| Olanzapine | 81.7 |
Oral Glucose Tolerance (NCT00741026)
Timeframe: 3 Days
| Intervention | min*mg/dl (Mean) |
|---|---|
| Placebo | 2808 |
| Olanzapine | 3984 |
Plasma Free Fatty Acid (NCT00741026)
Timeframe: 3 Days
| Intervention | mM (Mean) |
|---|---|
| Placebo | 0.38 |
| Olanzapine | 0.26 |
Leptin following placebo or olanzapine treatment (NCT00741026)
Timeframe: 3 Days
| Intervention | ng/ml (Mean) |
|---|---|
| Placebo | 6.8 |
| Olanzapine | 8.4 |
Systolic Blood Pressure (NCT00741026)
Timeframe: 3 Days
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | 113.3 |
| Olanzapine | 111.7 |
Total Cholesterol (NCT00741026)
Timeframe: 3 Days
| Intervention | mg/dl (Mean) |
|---|---|
| Placebo | 156.8 |
| Olanzapine | 152.6 |
Triglycerides (NCT00741026)
Timeframe: 3 Days
| Intervention | mg/dl (Mean) |
|---|---|
| Placebo | 88.9 |
| Olanzapine | 108.2 |
(NCT00427193)
Timeframe: Baseline to 12 months
| Intervention | degrees Celsius (Mean) |
|---|---|
| Caloric Restriction (CR) | -0.05 |
| Ad Libitum | -0.03 |
(NCT00427193)
Timeframe: Baseline to 24 months
| Intervention | degrees Celsius (Mean) |
|---|---|
| Prescribed 25% Caloric Restriction | -0.05 |
| Ad Libitum | -0.02 |
Difference in change in Fat Mass between prescribed 25% Caloric Restriction (CR) and Ad Libitum (AL) at 12 and 24 months as measured by dual X-ray absorptiometry (DXA) using the Hologic 4500A, Delphi W or Discovery A, by a standardized protocol according to a standardized protocol. Fat Mass (FM) was determined for the whole body. (NCT00427193)
Timeframe: baseline, 12 months
| Intervention | Kg (Mean) |
|---|---|
| Prescribed 25% Caloric Restriction | -6.1 |
| Ad Libitum | -0.3 |
Difference in change in Fat Mass between prescribed 25% Caloric Restriction (CR) and Ad Libitum (AL) at 12 and 24 months as measured by dual X-ray absorptiometry (DXA) using the Hologic 4500A, Delphi W or Discovery A, by a standardized protocol according to a standardized protocol. Fat Mass (FM) was determined for the whole body. (NCT00427193)
Timeframe: change 0 to 24 months
| Intervention | kg (Mean) |
|---|---|
| Prescribed 25% Caloric Restriction | -6.1 |
| Ad Libitum | -0.2 |
(NCT00427193)
Timeframe: Baseline, 24 months
| Intervention | Kcal/day (Mean) |
|---|---|
| Caloric Restriction (CR) | -71 |
| Ad Libitum | -7 |
(NCT00427193)
Timeframe: Baseline, 12 months
| Intervention | Kcal/day (Mean) |
|---|---|
| Caloric Restriction (CR) | -83 |
| Ad Libitum | -1 |
(NCT00427193)
Timeframe: change baseline to 12 months
| Intervention | pg/mL (Mean) |
|---|---|
| Caloric Restriction (CR) | -0.30 |
| Ad Libitum | -0.34 |
26 reviews available for carnitine and Insulin Sensitivity
| Article | Year |
|---|---|
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials.
Topics: Biomarkers; Carnitine; Fatty Acids; Humans; Insulin Resistance | 2022 |
Effects of carnitine on glucose and lipid metabolic profiles and fertility outcomes in women with polycystic ovary syndrome: A systematic review and meta-analysis.
Topics: Carnitine; Cholesterol; Female; Fertility; Glucose; Humans; Insulin; Insulin Resistance; Lipids; Lip | 2023 |
Effects of L-carnitine supplementation on glucolipid metabolism: a systematic review and meta-analysis.
Topics: Adult; Carnitine; Dietary Supplements; Humans; Insulin; Insulin Resistance | 2023 |
Review: Lipid biology in the periparturient dairy cow: contemporary perspectives.
Topics: Animals; Carnitine; Cattle; Ceramides; Energy Metabolism; Fatty Acids; Female; Glucose; Glycerophosp | 2020 |
The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD).
Topics: Alanine Transaminase; Aspartate Aminotransferases; Cardiomyopathies; Carnitine; Dietary Supplements; | 2020 |
Role of carnitine and its derivatives in the development and management of type 2 diabetes.
Topics: Animals; Antioxidants; Carnitine; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Insulin Re | 2018 |
Potential roles of carnitine in patients with polycystic ovary syndrome: a systematic review.
Topics: Blood Glucose; Body Mass Index; Carnitine; Female; Humans; Insulin Resistance; Oxidative Stress; Pol | 2019 |
L-Carnitine for the treatment of a calcium channel blocker and metformin poisoning.
Topics: Aged; Antidotes; Antihypertensive Agents; Calcium Channel Blockers; Carnitine; Combined Modality The | 2013 |
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Ins | 2013 |
Metabolomics in diabetes, a review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Humans; Insu | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.
Topics: Caloric Restriction; Carnitine; Circadian Rhythm; Cryotherapy; Diabetes Mellitus, Type 2; Diet Thera | 2016 |
Using Metabolomic Profiles as Biomarkers for Insulin Resistance in Childhood Obesity: A Systematic Review.
Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Biomarkers; Carnitine; Child; Humans; Insulin Re | 2016 |
Fatty Acid Oxidation and Its Relation with Insulin Resistance and Associated Disorders.
Topics: Animals; Carnitine; Carnitine Acyltransferases; Deficiency Diseases; Diabetes Mellitus; Diet, High-F | 2016 |
Carnitine and type 2 diabetes.
Topics: Acyl Coenzyme A; Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Die | 2009 |
Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused?
Topics: Animals; Carnitine; Disease Models, Animal; Exercise; Humans; Insulin Resistance; Lipid Metabolism; | 2010 |
Muscle insulin resistance: assault by lipids, cytokines and local macrophages.
Topics: Adipose Tissue; Animals; Carnitine; Cytokines; Dietary Fats; Humans; Insulin; Insulin Resistance; Li | 2010 |
Risk factors and metabolic mechanisms in the pathogenesis of uraemic cardiac disease.
Topics: Albuminuria; Anemia, Iron-Deficiency; Calcium Phosphates; Carnitine; Heart Failure; Homocysteine; Hu | 2011 |
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders.
Topics: Acetylcarnitine; Animals; Cardiovascular Agents; Cardiovascular Diseases; Carnitine; Diabetes Mellit | 2011 |
Pharmacological effects and clinical applications of propionyl-L-carnitine.
Topics: Adenosine Triphosphate; Atherosclerosis; Carbohydrate Metabolism; Cardiotonic Agents; Carnitine; End | 2011 |
Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency.
Topics: Acetyl Coenzyme A; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Type 2; Dietary Supplements | 2012 |
Metabolic conditioning to attenuate the adverse effects of perioperative fasting and improve patient outcomes.
Topics: Arginine; Carbohydrate Metabolism; Carnitine; Critical Illness; Dietary Supplements; Elective Surgic | 2012 |
Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine.
Topics: Carnitine; Energy Metabolism; Fatty Acids; Gene Expression Regulation; Genes, Mitochondrial; Homeost | 2013 |
Acylcarnitines: reflecting or inflicting insulin resistance?
Topics: Animals; Carnitine; Citric Acid Cycle; Fatty Acids; Humans; Insulin Resistance; Lipid Metabolism; Ox | 2013 |
The carnitine system and body composition.
Topics: Animals; Body Composition; Carnitine; Homeostasis; Humans; Insulin Resistance; Mitochondria; Models, | 2003 |
Carnitine system in uremic patients: molecular and clinical aspects.
Topics: Carnitine; Humans; Inflammation; Insulin Resistance; Renal Dialysis; Uremia | 2004 |
Carnitine in type 2 diabetes.
Topics: Carnitine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Lipid Metabolism; Organic Cation T | 2004 |
29 trials available for carnitine and Insulin Sensitivity
| Article | Year |
|---|---|
The effect of L-carnitine supplementation on insulin resistance, sex hormone-binding globulin and lipid profile in overweight/obese women with polycystic ovary syndrome: a randomized clinical trial.
Topics: Carnitine; Cholesterol, HDL; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin; Insu | 2022 |
The effect of l-carnitine supplementation on serum levels of omentin-1, visfatin and SFRP5 and glycemic indices in patients with pemphigus vulgaris: A randomized, double-blind, placebo-controlled clinical trial.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Blood Glucose; Carnitine; Cytokines; Dietary Supp | 2020 |
L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility.
Topics: Adult; Carnitine; Cross-Over Studies; Emulsions; Fatty Acids, Nonesterified; Humans; Infusion Pumps; | 2020 |
Plasma Palmitoyl-Carnitine (AC16:0) Is a Marker of Increased Postprandial Nonesterified Incomplete Fatty Acid Oxidation Rate in Adults With Type 2 Diabetes.
Topics: Adult; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female | 2018 |
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Topics: Aged; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glyca | 2018 |
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose | 2019 |
l-Carnitine plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effects: a randomized clinical trial.
Topics: Adult; Blood Glucose; Carnitine; Clomiphene; Drug Resistance; Female; Fertility Agents, Female; Horm | 2019 |
Randomized controlled trial of N-acetylcysteine versus l-carnitine among women with clomiphene-citrate-resistant polycystic ovary syndrome.
Topics: Acetylcysteine; Adult; Carnitine; Clomiphene; Double-Blind Method; Female; Follicle Stimulating Horm | 2019 |
Effect of an L-carnitine-containing peritoneal dialysate on insulin sensitivity in patients treated with CAPD: a 4-month, prospective, multicenter randomized trial.
Topics: Adult; Aged; Carnitine; Dialysis Solutions; Female; Glucose; Glucose Clamp Technique; Humans; Insuli | 2013 |
Effect of carnitine-orotate complex on glucose metabolism and fatty liver: a double-blind, placebo-controlled study.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Blood Glucose; Carnitine; DNA | 2014 |
Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Blood Glucose; Carnitine; Cholesterol, HDL; Dietary Supplement | 2015 |
Type 2 diabetes is associated with postprandial amino acid measures.
Topics: Adult; Amino Acids; Biomarkers; Carnitine; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resist | 2016 |
A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the relationship between sleep and insulin resistance.
Topics: Adult; Carnitine; Fasting; Female; Humans; Insulin Resistance; Male; Metabolomics; Sleep | 2016 |
Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Body Weights and Measures; Carnitine; Dietar | 2016 |
Assessment of plasma acylcarnitines before and after weight loss in obese subjects.
Topics: Adult; Anthropometry; Body Composition; Carnitine; Diabetes Mellitus, Type 2; Fatty Acids; Fatty Aci | 2016 |
Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients.
Topics: Aged; Appetite Depressants; Blood Glucose; Body Weight; C-Reactive Protein; Carnitine; Cholesterol; | 2011 |
Relationship between carnitine, fatty acids and insulin resistance.
Topics: Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Diabetes, Gestational; F | 2009 |
Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients.
Topics: Anti-Obesity Agents; Body Weight; Carnitine; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy | 2010 |
Sibutramine and L-carnitine compared to sibutramine alone on insulin resistance in diabetic patients.
Topics: Blood Glucose; Carnitine; Cyclobutanes; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy | 2010 |
Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients.
Topics: Adiponectin; Anti-Inflammatory Agents; Anti-Obesity Agents; Blood Glucose; Body Mass Index; Body Wei | 2011 |
Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women.
Topics: Adiposity; Adult; Aging; Amino Acids; Body Composition; Caloric Restriction; Carnitine; Cross-Sectio | 2011 |
Perioperative perturbations in carnitine metabolism are attenuated by preoperative carbohydrate treatment: Another mechanism by which preoperative feeding may attenuate development of postoperative insulin resistance.
Topics: Acylation; Adolescent; Adult; Aged; Aged, 80 and over; Antioxidants; Body Mass Index; Carnitine; Cho | 2012 |
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N | 2012 |
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N | 2012 |
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N | 2012 |
Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.
Topics: Adult; Amino Acids; Caloric Restriction; Carnitine; Energy Intake; Exercise; Fasting; Fatty Acids, N | 2012 |
Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months' consumption of a combination of bioactive food ingredients in overweight subjects.
Topics: Adipokines; Adult; Alkaloids; Benzodioxoles; Capsaicin; Carnitine; Catechin; Diet, Reducing; Dietary | 2013 |
L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response.
Topics: Adult; Blood Glucose; C-Peptide; Carbohydrate Metabolism; Carnitine; Drug Administration Schedule; D | 2003 |
Weight loss favorably modifies anthropometrics and reverses the metabolic syndrome in premenopausal women.
Topics: Adult; Anthropometry; Body Composition; Carnitine; Diet, Reducing; Dietary Proteins; Dietary Supplem | 2005 |
Insulin action on glucose and protein metabolism during L-carnitine supplementation in maintenance haemodialysis patients.
Topics: Aged; Carnitine; Double-Blind Method; Female; Glucose; Humans; Injections, Intravenous; Insulin; Ins | 2008 |
L-carnitine improves glucose disposal in type 2 diabetic patients.
Topics: Analysis of Variance; Anthropometry; Basal Metabolism; Carnitine; Diabetes Mellitus, Type 2; Female; | 1999 |
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Carnitine; Dideox | 2001 |
95 other studies available for carnitine and Insulin Sensitivity
| Article | Year |
|---|---|
High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models.
Topics: Alloxan; Animals; Carcinogenesis; Carnitine; Diet, High-Fat; Disease Models, Animal; Glucose Intoler | 2022 |
Effect of high-fat diet on peripheral blood mononuclear cells and adipose tissue in early stages of diet-induced weight gain.
Topics: Animals; Autophagy; Carnitine; Diet, High-Fat; Homeostasis; Inflammation; Insulin; Insulin Resistanc | 2019 |
Possible role of l-carnitine in improvement of metabolic and hepatic changes in hyperuricemic and hyperuricemic-Fructose-supplemented rats.
Topics: Animals; Carnitine; Fructose; Hyperuricemia; Insulin Resistance; Liver; Male; Oxidative Stress; Rats | 2019 |
Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Gene Deletion; Glucose; Homeostasis; Insulin; | 2020 |
Plasma Metabolomic Markers of Insulin Resistance and Diabetes and Rate of Incident Parkinson's Disease.
Topics: Adult; Aged; Biomarkers; Carnitine; Diabetes Mellitus; Female; Humans; Insulin Resistance; Male; Met | 2020 |
Metabolic Effects of Gastric Bypass Surgery: Is It All About Calories?
Topics: Adult; Blood Glucose; Caloric Restriction; Carnitine; Diabetes Mellitus, Type 2; Fasting; Female; Ga | 2020 |
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, T | 2021 |
Liraglutide treatment and acylcarnitine profiles in Egyptian obese insulin-resistant females.
Topics: Adult; Anti-Obesity Agents; Biomarkers; Blood Glucose; Carnitine; Case-Control Studies; Egypt; Femal | 2021 |
Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Female; Humans; Insulin Resistance; Mice; Obes | 2020 |
The Effects of Vitamin E, Silymarin and Carnitine on the Metabolic Abnormalities Associated with Nonalcoholic Liver Disease.
Topics: Blood Glucose; Carnitine; Glucose; Humans; Insulin; Insulin Resistance; Liver; Metabolic Syndrome; N | 2022 |
Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution.
Topics: Adult; Carnitine; Citric Acid Cycle; Cohort Studies; Female; Glucose Clamp Technique; Glucose Tolera | 2021 |
Association of plasma acylcarnitines with insulin sensitivity, insulin secretion, and prediabetes in a biracial cohort.
Topics: Adult; Blood Glucose; Carnitine; Cross-Sectional Studies; Glucose Intolerance; Humans; Insulin Resis | 2021 |
Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism.
Topics: Animals; Carnitine; CHO Cells; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Insulin; Insulin Re | 2021 |
Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway.
Topics: Animals; Body Weight; Carnitine; Carnitine O-Acetyltransferase; Diabetes Mellitus, Type 2; Humans; I | 2021 |
Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.
Topics: Aging; Animals; Blood Glucose; Carnitine; Cell Line; Ceramides; Female; Gene Expression Regulation; | 2017 |
Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups.
Topics: Amino Acids; Blood Glucose; Body Mass Index; Carnitine; Cohort Studies; Female; Gestational Age; Glu | 2017 |
Acute and long-term administration of palmitoylcarnitine induces muscle-specific insulin resistance in mice.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Carnitine; Dietary Fats; Energy Metabolism; Glucose | 2017 |
Profiling of Acylcarnitines in First Episode Psychosis before and after Antipsychotic Treatment.
Topics: Adolescent; Adult; Antipsychotic Agents; Biomarkers; Body Mass Index; Carnitine; Chromatography, Liq | 2017 |
Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction.
Topics: Animals; Autophagosomes; Autophagy; Carnitine; Diet, High-Fat; Glucose Intolerance; Insulin; Insulin | 2018 |
Effect of L-carnitine on diabetes-induced changes of skeletal muscles in rats.
Topics: Animals; Antioxidants; Carnitine; Catalase; Diabetes Mellitus, Experimental; Glucose; Glutathione; G | 2018 |
Short communication: Circulating fatty acylcarnitines are elevated in overweight periparturient dairy cows in association with sphingolipid biomarkers of insulin resistance.
Topics: Animals; Biomarkers; Carnitine; Cattle; Cattle Diseases; Ceramides; Fatty Acids; Female; Insulin Res | 2018 |
Insulin-resistance in glycogen storage disease type Ia: linking carbohydrates and mitochondria?
Topics: Acids; Adolescent; Adult; Antiporters; Biomarkers; Carnitine; Case-Control Studies; Child; Child, Pr | 2018 |
Metabolomic signatures of low birthweight: Pathways to insulin resistance and oxidative stress.
Topics: Adolescent; Adult; Aged; Carnitine; Cohort Studies; Dipeptides; Female; Fetal Growth Retardation; Fi | 2018 |
Remodeling of skeletal muscle mitochondrial proteome with high-fat diet involves greater changes to β-oxidation than electron transfer proteins in mice.
Topics: Adenosine Triphosphate; Animals; Carnitine; Cell Respiration; Chromatography, Liquid; Diet, Fat-Rest | 2018 |
Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance.
Topics: 3T3-L1 Cells; Aged; Animals; Carnitine; Diabetes Mellitus, Type 2; Glucose; Glucose Tolerance Test; | 2018 |
The effect of high-fat diet and inhibition of ceramide production on insulin action in liver.
Topics: Animals; Biomarkers; Blood Glucose; Carnitine; Carnitine O-Palmitoyltransferase; Ceramides; Diet, Hi | 2019 |
The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells.
Topics: Animals; Biological Transport; Carnitine; Cell Line; Fatty Acids; Glycolysis; Insulin; Insulin Resis | 2019 |
Improvement of insulin resistance via increase of GLUT4 and PPARγ in metabolic syndrome-induced rats treated with omega-3 fatty acid or l-carnitine.
Topics: Adiposity; Animals; Carnitine; Diet, Carbohydrate Loading; Diet, High-Fat; Dietary Supplements; Fatt | 2018 |
Metabolomic profiles and development of metabolic risk during the pubertal transition: a prospective study in the ELEMENT Project.
Topics: Acetylcarnitine; Adolescent; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Asparagine; Biomark | 2019 |
Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice.
Topics: Adaptor Proteins, Signal Transducing; Amino Acids; AMP-Activated Protein Kinases; Animals; Autophagy | 2018 |
Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome.
Topics: Absorptiometry, Photon; Adipose Tissue; Adolescent; Amino Acids; Blood Glucose; Body Composition; Ca | 2019 |
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
Topics: Acetylation; Acyl-CoA Dehydrogenase, Long-Chain; Animals; Berberine; Carnitine; Diet, High-Fat; Drug | 2019 |
The Impact of OMEGA-3 Fatty Acids Supplementation on Insulin Resistance and Content of Adipocytokines and Biologically Active Lipids in Adipose Tissue of High-Fat Diet Fed Rats.
Topics: Adiponectin; Adipose Tissue; Animals; Blood Glucose; Carnitine; Carnitine O-Palmitoyltransferase; Ce | 2019 |
Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes.
Topics: Aged; Biomarkers; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Insuli | 2019 |
Effects of L-carnitine on Polycystic Ovary Syndrome.
Topics: Adult; Blood Glucose; Body Mass Index; Carnitine; Dehydroepiandrosterone; Female; Humans; Insulin; I | 2019 |
Hyperinsulinemia and skeletal muscle fatty acid trafficking.
Topics: Adult; Carbon Radioisotopes; Carnitine; Cohort Studies; Down-Regulation; Fatty Acids, Nonesterified; | 2013 |
Impaired mitochondrial β-oxidation in patients with chronic hepatitis C: relation with viral load and insulin resistance.
Topics: Adult; Aged; Carnitine; Fasting; Fatty Acids; Fatty Liver; Female; Hepatitis C, Chronic; Homeostasis | 2013 |
Effect of cholecalciferol and levo carnitine on plasma glucose, plasma insulin and insulin resistance in type 2 diabetic rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Carnitine; Cholecalciferol; Diabetes Mellitus, Experim | 2013 |
Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.
Topics: Aconitate Hydratase; Animals; Carnitine; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Disease P | 2014 |
Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation.
Topics: Adult; Carnitine; Fatty Acids, Omega-3; Fish Oils; Glycogen; Humans; Insulin; Insulin Resistance; Li | 2014 |
Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Algorithms; Animals; Carnitine; Cluster Analysis; Fast | 2014 |
The effect of long-term oral L-carnitine administration on insulin sensitivity, glucose disposal, plasma concentrations of leptin and acylcarnitines, and urinary acylcarnitine excretion in warmblood horses.
Topics: Animals; Carnitine; Glucose Clamp Technique; Horses; Insulin Resistance; Leptin; Male; Plasma; Radio | 2014 |
Acylcarnitines: potential implications for skeletal muscle insulin resistance.
Topics: Adult; Animals; Antioxidants; Carnitine; Case-Control Studies; Cell Line; Cells, Cultured; Cytokines | 2015 |
Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.
Topics: Animals; Carnitine; Citric Acid Cycle; Dietary Fats; Enzyme Activation; Fatty Acids; Glucose; Glycog | 2014 |
Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning.
Topics: Adaptation, Physiological; Adiposity; Animals; Blood Glucose; Body Weight; Butyric Acid; Carnitine; | 2015 |
Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats.
Topics: Animals; Carnitine; Dietary Supplements; DNA, Mitochondrial; Gene Expression Regulation; Genetic Pre | 2015 |
Effect of a β-Hydroxyphosphonate Analogue of ʟ-Carnitine on Insulin-Sensitive and Insulin-Resistant 3T3-L1 Adipocytes.
Topics: 3T3-L1 Cells; 4-Chloro-7-nitrobenzofurazan; Adipocytes; Adipogenesis; Animals; Carnitine; Cell Diffe | 2015 |
MK2 Deletion in Mice Prevents Diabetes-Induced Perturbations in Lipid Metabolism and Cardiac Dysfunction.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fatty Acids, Noneste | 2016 |
Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diet, High-Fa | 2016 |
UHPLC/Q-TOFMS-based plasma metabolomics of polycystic ovary syndrome patients with and without insulin resistance.
Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Chromatography, High Pressure Liquid; Fatty Acid | 2016 |
Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity.
Topics: Animals; Carbon Isotopes; Carnitine; Ceramides; Chromatography, Liquid; Citric Acid Cycle; Dietary F | 2016 |
Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry.
Topics: Adult; Amino Acids; Bile Acids and Salts; Bilirubin; Biomarkers; Carnitine; Chromatography, High Pre | 2016 |
The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice.
Topics: Animals; Betaine; Carnitine; Dietary Fats; Energy Metabolism; Glucose Intolerance; Insulin Resistanc | 2016 |
Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy.
Topics: Absorptiometry, Photon; Adipose Tissue; Adiposity; Adult; Amino Acids, Branched-Chain; Anti-Retrovir | 2016 |
Plasma Acylcarnitines and Amino Acid Levels As an Early Complex Biomarker of Propensity to High-Fat Diet-Induced Obesity in Mice.
Topics: Amino Acids; Analysis of Variance; Animals; Biomarkers; Blood Glucose; Carnitine; Cluster Analysis; | 2016 |
Effect of Exercise and Calorie Restriction on Tissue Acylcarnitines, Tissue Desaturase Indices, and Fat Accumulation in Diet-Induced Obese Rats.
Topics: Animals; Caloric Restriction; Carnitine; Diet, High-Fat; Disease Models, Animal; Fatty Acid Desatura | 2016 |
Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women.
Topics: Adult; Aged; Blood Cells; Blood Glucose; Body Mass Index; Carnitine; Diabetes Mellitus, Type 2; Fema | 2017 |
Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction.
Topics: Acetyl-CoA Carboxylase; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Carnitine; Female; Gluco | 2016 |
Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men.
Topics: Adult; Birth Weight; Carnitine; Citric Acid Cycle; Cross-Over Studies; Denmark; Diabetes Mellitus, T | 2016 |
Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes.
Topics: Animals; Carnitine; Cell Line; Ceramides; Diglycerides; Fatty Acids; Insulin; Insulin Resistance; Mi | 2016 |
Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons.
Topics: Adenosine Triphosphate; Adult; Amino Acids, Branched-Chain; Biomarkers; Carnitine; Citric Acid Cycle | 2017 |
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity.
Topics: Antineoplastic Agents; Benzhydryl Compounds; beta Catenin; Carnitine; Cell Proliferation; Drug Evalu | 2017 |
Plasma L-carnitine levels of obese and non-obese polycystic ovary syndrome patients.
Topics: Adolescent; Adult; Body Mass Index; Carnitine; Case-Control Studies; Cross-Sectional Studies; Female | 2017 |
Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation.
Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Carnitine O-Acetyltransferas | 2017 |
Muscle acylcarnitines during short-term fasting in lean healthy men.
Topics: Adult; Anthropometry; Blood Glucose; Calorimetry, Indirect; Carnitine; Fasting; Humans; Insulin Resi | 2009 |
Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
Topics: Adolescent; Adult; Aged; Amino Acids; Blood Glucose; Carnitine; Cross-Sectional Studies; Fatty Acids | 2009 |
Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats.
Topics: Animals; Carnitine; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2009 |
Oral carnitine therapy and insulin resistance.
Topics: Administration, Oral; Carnitine; Female; Humans; Hypertension; Insulin Resistance; Male; Prognosis; | 2010 |
Increased mitochondrial content rescues in vivo muscle oxidative capacity in long-term high-fat-diet-fed rats.
Topics: Animals; Carnitine; Diet; Dietary Fats; Insulin Resistance; Male; Mitochondria, Muscle; Muscle, Skel | 2010 |
LMNA mutations, skeletal muscle lipid metabolism, and insulin resistance.
Topics: Adult; Blood Glucose; Carnitine; Cells, Cultured; Energy Metabolism; Female; Glycogen; Humans; Insul | 2010 |
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Carnitine; Clozapine; Energy Metabolism; Fatty Acids | 2012 |
The effects of long- or medium-chain fat diets on glucose tolerance and myocellular content of lipid intermediates in rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Body Weight; Carnitine; Dietary Fat | 2011 |
Selective reversible inhibition of liver carnitine palmitoyl-transferase 1 by teglicar reduces gluconeogenesis and improves glucose homeostasis.
Topics: Analysis of Variance; Animals; Area Under Curve; Carnitine; Carnitine O-Palmitoyltransferase; Diabet | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes.
Topics: Carnitine; Case-Control Studies; Cell Respiration; Citrate (si)-Synthase; Diabetes Mellitus, Type 2; | 2011 |
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalytic Domain; Diabetes Mellitus, Type 2; E | 2011 |
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system.
Topics: Adipocytes; Carnitine; Coculture Techniques; Fatty Acids, Nonesterified; Female; Gene Expression; Gl | 2011 |
Efficacy and safety of two analogs of L-carnitine on rats made insulin resistant by a high-fructose diet.
Topics: Animals; Blood Glucose; Body Weight; Carnitine; Chick Embryo; Cholesterol; Diet; Disease Models, Ani | 2011 |
Regular endurance exercise improves the diminished hepatic carnitine status in mice fed a high-fat diet.
Topics: Acetylcarnitine; Animals; Body Weight; Carnitine; Diet, High-Fat; Fatty Acids; Gene Expression Regul | 2011 |
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects.
Topics: Adult; Carnitine; Ceramides; Diglycerides; Female; Glucose; Humans; Insulin Resistance; Liver; Male; | 2012 |
Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Carbon; Carnitine; Carnitine O-Acetyltransferase; Cells | 2012 |
[The function of mitochondrion, carnitine, coenzyme-A, fat acids, glucose, the Randle cycle and insulin: a lecture].
Topics: Blood Glucose; Carnitine; Coenzyme A; Energy Metabolism; Fatty Acids; Humans; Insulin; Insulin Resis | 2012 |
Consumption of a high β-glucan barley flour improves glucose control and fatty liver and increases muscle acylcarnitines in the Zucker diabetic fatty rat.
Topics: Adiponectin; Animals; beta-Glucans; Blood Glucose; Body Weight; Carnitine; Cholesterol; Diabetes Mel | 2013 |
Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis.
Topics: Adult; Body Mass Index; Carnitine; Electron Transport; Fatty Acids; Fatty Liver; Female; Humans; Ins | 2003 |
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.
Topics: Acyl Coenzyme A; Adenoviridae; Animals; Carboxy-Lyases; Carnitine; Cells, Cultured; Dietary Fats; He | 2004 |
Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.
Topics: 3-Hydroxybutyric Acid; Animals; Antigens, CD; Antigens, Differentiation; Biotin; Carcinoembryonic An | 2004 |
Gestational diabetes exhibits lack of carnitine deficiency despite relatively low carnitine levels and alterations in ketogenesis.
Topics: 3-Hydroxybutyric Acid; Adult; Body Mass Index; Body Weight; Carnitine; Case-Control Studies; Diabete | 2005 |
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.
Topics: Animals; Carnitine; Coenzyme A; Dietary Fats; Dietary Sucrose; Fatty Liver; Female; Glycerol-3-Phosp | 2005 |
Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Coenzyme A Ligases; Diet; Diet | 2006 |
Key role of insulin resistance in vascular injury among hemodialysis patients.
Topics: Aged; Blood Pressure; Carnitine; Cyclohexanes; Diabetic Nephropathies; Female; Homeostasis; Humans; | 2007 |
Carnitine revisited: potential use as adjunctive treatment in diabetes.
Topics: Animals; Calorimetry; Carnitine; Diabetes Mellitus, Experimental; Fatty Acids; Glucose Tolerance Tes | 2007 |
Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet.
Topics: Animals; Antioxidants; Blood Glucose; Carnitine; Diet; Dose-Response Relationship, Drug; Fructose; I | 2007 |
Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet.
Topics: Animals; Antioxidants; Blood Glucose; Carnitine; Diet; Dose-Response Relationship, Drug; Fructose; I | 2007 |
Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet.
Topics: Animals; Antioxidants; Blood Glucose; Carnitine; Diet; Dose-Response Relationship, Drug; Fructose; I | 2007 |
Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet.
Topics: Animals; Antioxidants; Blood Glucose; Carnitine; Diet; Dose-Response Relationship, Drug; Fructose; I | 2007 |
Beneficial impact of L-carnitine in liver: a study in a rat model of syndrome X.
Topics: Administration, Oral; Animals; Carnitine; Disease Models, Animal; Fructose; Injections, Intraperiton | 2008 |
Changes in redox ratio and protein glycation in precataractous lens from fructose-fed rats: effects of exogenous L-carnitine.
Topics: Animals; Antioxidants; Blood Glucose; Carnitine; Catalase; Cataract; Dietary Carbohydrates; Disease | 2008 |
Serum total L-carnitine levels in non-obese women with polycystic ovary syndrome.
Topics: Adolescent; Adult; Blood Glucose; Carnitine; Cholesterol, HDL; Dehydroepiandrosterone Sulfate; Femal | 2008 |
The effect of pivalate treatment of pregnant rats on body mass and insulin levels in the adult offspring.
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Blood Glucose; Carnitine; Female; Hyperinsulinism; | 2001 |