Page last updated: 2024-10-16

carnitine and Innate Inflammatory Response

carnitine has been researched along with Innate Inflammatory Response in 83 studies

Research Excerpts

ExcerptRelevanceReference
" The levels of LC, antioxidant status (malondialdehyde and antioxidant enzymes activities), and inflammation markers (C-reactive protein [CRP], interleukin [IL]-6, and tumor necrosis factor [TNF]-α) were measured."9.20Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients. ( Lee, BJ; Lin, JS; Lin, PT; Lin, YC, 2015)
"To evaluate the effects of 1-year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and inflammatory parameters in obese type 2 diabetic patients."9.15Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2011)
"The study indicates that l-carnitine supplement reduces serum SAA, which is a risk factor for cardiovascular diseases in hemodialysis patients, but has no effect on vascular inflammation markers."9.15Effects of l-carnitine supplement on serum amyloid A and vascular inflammation markers in hemodialysis patients: a randomized controlled trial. ( Hakeshzadeh, F; Hedayati, M; Malakoutian, T; Tabibi, H, 2011)
"Our study wants to evaluate the effects of one year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and insulin resistance state in type 2 diabetic patients."9.14Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2010)
"Salicylic acid has been used as an anti-acne agent with its comedolytic property and antimicrobial activity."8.31Anti-acne activity of carnitine salicylate and magnolol through the regulation of exfoliation, lipogenesis, bacterial growth and inflammation. ( Kim, MS; Kwon, KC; Park, SW; Shin, YW; Song, YS; Won, JG, 2023)
"These findings supported the protective effects of l-carnitine on rat testes due to suppression of oxidative stress, inflammation and enhancing autophagy."8.12l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity. ( Khedr, NF; Werida, RH, 2022)
"The study aimed at studying the hepatoprotective effect of l-carnitine against lead (Pb) acetate-induced hepatocellular injury, emphasizing the role of caspase-3 and glycogen synthase kinase-3β in hepatocellular apoptosis and inflammation."8.12Effect of l-carnitine supplementation on lead acetate-induced liver cell apoptosis and inflammation: role of caspase-3 and glycogen synthase kinase-3β enzymes. ( Abdel-Emam, RA; Ali, MF, 2022)
"L-carnitine has been shown to exert neuroprotective effects on cerebral ischemia, mainly by improving mitochondrial function and reducing inflammation."8.12Association Between Plasma L-Carnitine and Cognitive Impairment in Patients with Acute Ischemic Stroke. ( Bu, X; Che, B; Chen, H; He, J; Ju, Z; Peng, H; Wang, A; Xu, T; Zhang, J; Zhang, Y; Zhong, C, 2022)
" The aim of this cross-sectional study was to explore whole-blood FA, serum lipid composition, and carnitine- and choline derivatives in 78 RA outpatients with different degrees of periodontal inflammation."8.02Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation. ( Berge, RK; Beyer, K; Bjørndal, B; Bolstad, AI; Brun, JG; Lie, SA; Svardal, A, 2021)
"Polycystic ovary syndrome (PCOS) is related to low levels of serum l-carnitine, which has antioxidant, anti-inflammatory and antiapoptotic properties."7.91L-Carnitine improves endocrine function and folliculogenesis by reducing inflammation, oxidative stress and apoptosis in mice following induction of polycystic ovary syndrome. ( Azadbakht, M; Kalhori, Z; Mehranjani, MS; Shariatzadeh, MA, 2019)
"Insulin resistance may be linked to incomplete fatty acid β-oxidation and the subsequent increase in acylcarnitine species in different tissues including skeletal muscle."7.81Acylcarnitines: potential implications for skeletal muscle insulin resistance. ( Adams, SH; Aguer, C; Dent, R; Harper, ME; Hwang, DH; Knotts, TA; McCoin, CS; McPherson, R; Ono-Moore, K; Thrush, AB, 2015)
"This study was carried out to assess the protective bone-sparing effect of carnitine with anti-inflammatory properties on chronic inflammation-induced bone loss in ovariectomised (OVX) rats."7.79The role of carnitine on ovariectomy and inflammation-induced osteoporosis in rats. ( Ayan, AK; Aydin, A; Bayir, Y; Bilen, H; Cadirci, E; Ferah, I; Halici, Z; Orsal, E; Ozaltin, S; Ozkanlar, S; Seven, B, 2013)
"Cancer cachexia (CC), a progressive loss of body mass, leads to malnutrition and deficiencies of essential substances including polyunsaturated fatty acids (PUFAs) and L-carnitine (LC)."7.78L-carnitine and cancer cachexia. II. Effects of lipid emulsion used in total parenteral nutrition on parameters of hemostasis and inflammatory state in L-carnitine deficiency in myocytes. ( Ciesielski, M; Jankun, J; Kawecki, K; Kruszewski, WJ; Lysiak-Szydłowska, W; Szajewski, M; Szefel, J, 2012)
"Inflammation is a common complication in hemodialysis (HD) patients with no valid treatment strategy."6.52Inflammation and L-carnitine therapy in hemodialysis patients: a review. ( Khalatbari-Soltani, S; Tabibi, H, 2015)
"L-carnitine was reported for its anti-oxidant and anti-inflammatory activities."5.91L-carnitine Modulates Cognitive Impairment Induced by Doxorubicin and Cyclophosphamide in Rats; Insights to Oxidative Stress, Inflammation, Synaptic Plasticity, Liver/brain, and Kidney/brain Axes. ( George, MY; Menze, ET; Morid, OF; Tadros, MG, 2023)
"Given the significant reductions in IL-6 and FBS levels, L-carnitine supplementation appeared to have some positive effects on the inflammation, blood glucose control, and prevention of cardiovascular events in these patients, as well as the improvement of quality of life."5.51Effect of L-Carnitine Supplementation on Inflammatory Markers and Serum Glucose in Hemodialysis Children: A Randomized, Placebo-Controlled Clinical Trial. ( Hamedi-Kalajahi, F; Imani, H; Mojtahedi, S; Shabbidar, S, 2022)
"Significant differences between our groups showed that L-Carnitine could help hemodialysis patients with cardiopulmonary problems to suffer lower rate of inflammation and poor life quality as shown at least in comparison of the two factors including CRP and PETCO2 at rest."5.34Can L-Carnitine Supplementation Improve Cardiopulmonary Function? A Randomized Controlled Clinical Trial in Hemodialysis Patients. ( Dastan, F; Eslaminejad, A; Maleki Kazeri, F; Marashian, SM; Yassari, F, 2020)
" The levels of LC, antioxidant status (malondialdehyde and antioxidant enzymes activities), and inflammation markers (C-reactive protein [CRP], interleukin [IL]-6, and tumor necrosis factor [TNF]-α) were measured."5.20Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients. ( Lee, BJ; Lin, JS; Lin, PT; Lin, YC, 2015)
"The study indicates that l-carnitine supplement reduces serum SAA, which is a risk factor for cardiovascular diseases in hemodialysis patients, but has no effect on vascular inflammation markers."5.15Effects of l-carnitine supplement on serum amyloid A and vascular inflammation markers in hemodialysis patients: a randomized controlled trial. ( Hakeshzadeh, F; Hedayati, M; Malakoutian, T; Tabibi, H, 2011)
"To evaluate the effects of 1-year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and inflammatory parameters in obese type 2 diabetic patients."5.15Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2011)
"Our study wants to evaluate the effects of one year treatment with orlistat plus L-carnitine compared to orlistat alone on body weight, glycemic and lipid control, and insulin resistance state in type 2 diabetic patients."5.14Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. ( Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Maffioli, P; Palumbo, I; Randazzo, S, 2010)
"Because carnitine has been shown to decrease oxidative stress and improve endothelial cell functioning, we examined the effects of carnitine supplementation on postprandial flow-mediated dilation (FMD) and circulating biomarkers of inflammation and oxidative stress after a high-fat meal."5.13Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults. ( Anderson, JM; Hatfield, DL; Judelson, DA; Kraemer, WJ; Maresh, CM; Quann, EE; Silvestre, R; Spiering, BA; Vingren, JL; Volek, JS; Yamamoto, LM, 2008)
"Salicylic acid has been used as an anti-acne agent with its comedolytic property and antimicrobial activity."4.31Anti-acne activity of carnitine salicylate and magnolol through the regulation of exfoliation, lipogenesis, bacterial growth and inflammation. ( Kim, MS; Kwon, KC; Park, SW; Shin, YW; Song, YS; Won, JG, 2023)
"The study aimed at studying the hepatoprotective effect of l-carnitine against lead (Pb) acetate-induced hepatocellular injury, emphasizing the role of caspase-3 and glycogen synthase kinase-3β in hepatocellular apoptosis and inflammation."4.12Effect of l-carnitine supplementation on lead acetate-induced liver cell apoptosis and inflammation: role of caspase-3 and glycogen synthase kinase-3β enzymes. ( Abdel-Emam, RA; Ali, MF, 2022)
"These findings supported the protective effects of l-carnitine on rat testes due to suppression of oxidative stress, inflammation and enhancing autophagy."4.12l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity. ( Khedr, NF; Werida, RH, 2022)
"L-carnitine has been shown to exert neuroprotective effects on cerebral ischemia, mainly by improving mitochondrial function and reducing inflammation."4.12Association Between Plasma L-Carnitine and Cognitive Impairment in Patients with Acute Ischemic Stroke. ( Bu, X; Che, B; Chen, H; He, J; Ju, Z; Peng, H; Wang, A; Xu, T; Zhang, J; Zhang, Y; Zhong, C, 2022)
" The aim of this cross-sectional study was to explore whole-blood FA, serum lipid composition, and carnitine- and choline derivatives in 78 RA outpatients with different degrees of periodontal inflammation."4.02Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation. ( Berge, RK; Beyer, K; Bjørndal, B; Bolstad, AI; Brun, JG; Lie, SA; Svardal, A, 2021)
"Plasma acylcarnitines [(C2, C16:1, C18, C18:1, C18:1-OH, and C18:2)], glycerophospholipids (lysophosphatidylcholine-acyl, -di-acyl, and -di-acyl acyl-alkyl) and sphingomyelins [SM (OH) C16:1, SM C18:0, SM C18:1, and SM C20:2] significantly increased on PND 145, when chronic inflammation was observed in the dorsolateral prostate of rats dosed with EB, T, and E."3.96Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones. ( Beger, RD; Cao, Z; Nakamura, N; Pence, LM, 2020)
"Polycystic ovary syndrome (PCOS) is related to low levels of serum l-carnitine, which has antioxidant, anti-inflammatory and antiapoptotic properties."3.91L-Carnitine improves endocrine function and folliculogenesis by reducing inflammation, oxidative stress and apoptosis in mice following induction of polycystic ovary syndrome. ( Azadbakht, M; Kalhori, Z; Mehranjani, MS; Shariatzadeh, MA, 2019)
"Insulin resistance may be linked to incomplete fatty acid β-oxidation and the subsequent increase in acylcarnitine species in different tissues including skeletal muscle."3.81Acylcarnitines: potential implications for skeletal muscle insulin resistance. ( Adams, SH; Aguer, C; Dent, R; Harper, ME; Hwang, DH; Knotts, TA; McCoin, CS; McPherson, R; Ono-Moore, K; Thrush, AB, 2015)
"The aim of this study was to examine the effects of carnitine on bone healing in ovariectomy (OVX) and inflammation (INF)-induced osteoporotic rats."3.81Treatment with Carnitine Enhances Bone Fracture Healing under Osteoporotic and/or Inflammatory Conditions. ( Aksakal, AM; Albayrak, A; Ayan, AK; Aydin, A; Bayir, Y; Cadirci, E; Halici, Z; Karakus, E; Polat, B; Yildirim, OS, 2015)
"We have previously shown that carboplatin induces inflammation and apoptosis in renal tubular cells (RTCs) through the activation of the nuclear factor of activated T cells-3 (NFAT3) protein by reactive oxygen species (ROS), and that the ROS-mediated activation of NFAT3 is prevented by N-acetyl cysteine and heme oxygenase-1 treatment."3.80L-carnitine protects against carboplatin-mediated renal injury: AMPK- and PPARα-dependent inactivation of NFAT3. ( Chang, CC; Chou, HC; Chou, Y; Juan, SH; Sue, YM; Yang, NJ, 2014)
"This study was carried out to assess the protective bone-sparing effect of carnitine with anti-inflammatory properties on chronic inflammation-induced bone loss in ovariectomised (OVX) rats."3.79The role of carnitine on ovariectomy and inflammation-induced osteoporosis in rats. ( Ayan, AK; Aydin, A; Bayir, Y; Bilen, H; Cadirci, E; Ferah, I; Halici, Z; Orsal, E; Ozaltin, S; Ozkanlar, S; Seven, B, 2013)
" Although the positive results obtained with this dietary intervention were not explained by biomarkers of endothelial function and inflammation, altered acylcarnitine levels indicate an improvement in skeletal muscle metabolism due to enhanced tissue perfusion."3.79Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease. ( Baldwin, A; Blewett, H; Guzman, RP; O, K; Taylor, CG; Weighell, W; Wright, B; Zahradka, P, 2013)
"Cancer cachexia (CC), a progressive loss of body mass, leads to malnutrition and deficiencies of essential substances including polyunsaturated fatty acids (PUFAs) and L-carnitine (LC)."3.78L-carnitine and cancer cachexia. II. Effects of lipid emulsion used in total parenteral nutrition on parameters of hemostasis and inflammatory state in L-carnitine deficiency in myocytes. ( Ciesielski, M; Jankun, J; Kawecki, K; Kruszewski, WJ; Lysiak-Szydłowska, W; Szajewski, M; Szefel, J, 2012)
"Obesity is an important worldwide public health problem and considered a disease of chronic low-grade inflammation."2.80Effect of L-carnitine supplementation in comparison with moderate aerobic training on serum inflammatory parameters in healthy obese women. ( Jafari, A; Karimi, M; Rafraf, M, 2015)
"Hypertension is the most prevalent chronic disease and a risk factor for various diseases."2.72TMA/TMAO in Hypertension: Novel Horizons and Potential Therapies. ( Ding, YJ; Jia, QJ; Li, YY; Lv, SC; Wang, YJ; Zhang, A; Zhang, JP; Zhang, WQ; Zhang, XN; Zhu, YP, 2021)
"Inflammation is a common complication in hemodialysis (HD) patients with no valid treatment strategy."2.52Inflammation and L-carnitine therapy in hemodialysis patients: a review. ( Khalatbari-Soltani, S; Tabibi, H, 2015)
"Carnitine is a small water-soluble molecule that is present in almost all animal species."2.42Carnitine system in uremic patients: molecular and clinical aspects. ( Bellinghieri, G; Benatti, P; Calvani, M; Monardo, P; Peluso, G; Santoro, D; Savica, V, 2004)
"L-carnitine was reported for its anti-oxidant and anti-inflammatory activities."1.91L-carnitine Modulates Cognitive Impairment Induced by Doxorubicin and Cyclophosphamide in Rats; Insights to Oxidative Stress, Inflammation, Synaptic Plasticity, Liver/brain, and Kidney/brain Axes. ( George, MY; Menze, ET; Morid, OF; Tadros, MG, 2023)
"Atherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression."1.72TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis. ( Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J, 2022)
"We have previously demonstrated that neuropathic pain after nerve damage is exacerbated in autophagy-defective heterozygous Ambra1 mice."1.48Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice. ( Ciavardelli, D; Coccurello, R; De Angelis, F; Giacovazzo, G; Magnaghi, V; Marinelli, S; Nazio, F; Procacci, P; Rossi, C; Vacca, V, 2018)
"Choline was not significantly altered in MetS."1.48Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome. ( Huet, B; Jialal, I; Lent-Schochet, D; McLaughlin, M; Silva, R, 2018)
"In experiment 1, induction of ketosis through feed restriction on d 5 postpartum upregulated FGF21, its co-receptor KLB, and PPARA but only elicited a numerical increase in serum FGF21 concentration."1.42Alterations in Hepatic FGF21, Co-Regulated Genes, and Upstream Metabolic Genes in Response to Nutrition, Ketosis and Inflammation in Peripartal Holstein Cows. ( Akbar, H; Batistel, F; Drackley, JK; Loor, JJ, 2015)
"Obesity has reached epidemic proportions worldwide."1.38Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. ( Brauer, HA; Freemerman, AJ; Galanko, JA; Ilkayeva, OR; Kuan, PF; Makowski, L; Muehlbauer, MJ; Newgard, CB; O'Connell, TM; Sampey, BP; Stevens, RD; Troester, MA; Zhang, J, 2012)
"Also, the presence of infection in these patients does increase, but not significantly, the nonesterified and acylcarnitine of both polymorphonuclear leukocytes and mononuclear cells from these patients."1.27Changes in carnitine in polymorphonuclear leukocytes, mononuclear cells, and plasma from patients with inflammatory disorders. ( Adlouni, HA; Férard, G; Katrib, K, 1988)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.41)18.7374
1990's1 (1.20)18.2507
2000's13 (15.66)29.6817
2010's39 (46.99)24.3611
2020's28 (33.73)2.80

Authors

AuthorsStudies
Khedr, NF1
Werida, RH1
Hamedi-Kalajahi, F1
Imani, H1
Mojtahedi, S1
Shabbidar, S1
Abdel-Emam, RA1
Ali, MF1
Che, B1
Chen, H2
Wang, A1
Peng, H1
Bu, X1
Zhang, J2
Ju, Z1
Xu, T1
He, J1
Zhong, C1
Zhang, Y3
Weng, M1
Zhang, W2
Zhang, Z2
Tang, Y1
Lai, W1
Dan, Z1
Liu, Y1
Zheng, J1
Gao, S1
Mai, K1
Ai, Q1
Shaforostova, EA1
Gureev, AP1
Volodina, DE1
Popov, VN1
Bae, JE1
Kim, JB1
Jo, DS1
Park, NY1
Kim, YH1
Lee, HJ1
Kim, SH2
Son, M1
Kim, P1
Ryu, HY1
Lee, WH1
Ryoo, ZY1
Lee, HS1
Jung, YK1
Cho, DH1
Sánchez-Quevedo, J1
Ocampo-Rodríguez, E1
Alvarez-Ayala, E1
Rodríguez-López, A1
Duarte-Vázquez, MA1
Rosado, JL1
Rodríguez-Fragoso, L1
Díez-Ricote, L1
Ruiz-Valderrey, P1
Micó, V1
Blanco, R1
Tomé-Carneiro, J1
Dávalos, A1
Ordovás, JM1
Daimiel, L1
Wang, L2
Yan, C1
Ai, C1
Wang, S1
Shen, C1
Tong, Y1
Song, S1
Morid, OF1
Menze, ET1
Tadros, MG1
George, MY1
Kwon, KC1
Won, JG1
Kim, MS1
Shin, YW1
Park, SW1
Song, YS1
Rastgoo, S1
Fateh, ST1
Nikbaf-Shandiz, M1
Rasaei, N1
Aali, Y1
Zamani, M1
Shiraseb, F1
Asbaghi, O1
Zhang, DM1
Guo, ZX1
Zhao, YL1
Wang, QJ1
Gao, YS1
Yu, T1
Chen, YK1
Chen, XM1
Wang, GQ1
Lowry, JE1
Tumurbaatar, B1
D'Agostino, C1
Main, E1
Wright, TJ1
Dillon, EL1
Saito, TB1
Porter, C1
Andersen, CR1
Brining, DL1
Endsley, JJ1
Sheffield-Moore, M1
Volpi, E1
Fang, R1
Abate, N1
Tuvdendorj, DR1
Aziz, MM1
Abd El Fattah, MA1
Ahmed, KA1
Sayed, HM1
Zhu, X2
Long, D2
Zabalawi, M1
Ingram, B2
Yoza, BK2
Stacpoole, PW1
McCall, CE2
Ottria, A1
Hoekstra, AT1
Zimmermann, M1
van der Kroef, M1
Vazirpanah, N1
Cossu, M1
Chouri, E1
Rossato, M1
Beretta, L1
Tieland, RG1
Wichers, CGK1
Stigter, E1
Gulersonmez, C1
Bonte-Mineur, F1
Berkers, CR1
Radstake, TRDJ1
Marut, W1
Crocetto, F1
Boccellino, M1
Barone, B1
Di Zazzo, E1
Sciarra, A1
Galasso, G1
Settembre, G1
Quagliuolo, L1
Imbimbo, C1
Boffo, S1
Angelillo, IF1
Di Domenico, M1
Nakamura, N1
Pence, LM1
Cao, Z1
Beger, RD1
Macpherson, ME1
Hov, JR1
Ueland, T1
Dahl, TB1
Kummen, M1
Otterdal, K1
Holm, K1
Berge, RK3
Mollnes, TE1
Trøseid, M1
Halvorsen, B1
Aukrust, P1
Fevang, B1
Jørgensen, SF1
Yassari, F1
Dastan, F1
Marashian, SM1
Eslaminejad, A1
Maleki Kazeri, F1
Pla, R1
Pujos-Guillot, E1
Durand, S1
Brandolini-Bunlon, M1
Centeno, D1
Pyne, DB1
Toussaint, JF1
Hellard, P1
Piccapane, F1
Bonomini, M1
Castellano, G1
Gerbino, A1
Carmosino, M1
Svelto, M1
Arduini, A1
Procino, G1
Beyer, K1
Lie, SA1
Bjørndal, B2
Svardal, A2
Brun, JG1
Bolstad, AI1
Zhang, WQ1
Wang, YJ1
Zhang, A1
Ding, YJ1
Zhang, XN1
Jia, QJ1
Zhu, YP1
Li, YY1
Lv, SC1
Zhang, JP1
Bellamine, A1
Pham, TNQ1
Jain, J1
Wilson, J1
Sahin, K1
Dallaire, F1
Seidah, NG1
Durkee, S1
Radošević, K1
Cohen, ÉA1
Fu, J1
Ma, X1
Guerreiro, G2
Faverzani, J1
Moura, AP1
Volfart, V1
Gome Dos Reis, B1
Sitta, A1
Gonzalez, EA1
de Lima Rosa, G1
Coitinho, AS2
Baldo, G1
Wajner, M2
Vargas, CR2
López-Cano, JJ1
González-Cela-Casamayor, MA1
Andrés-Guerrero, V1
Herrero-Vanrell, R1
Benítez-Del-Castillo, JM1
Molina-Martínez, IT1
Mohammadi, M1
Hajhossein Talasaz, A1
Alidoosti, M1
Lent-Schochet, D1
Silva, R1
McLaughlin, M1
Huet, B1
Jialal, I1
Adefisayo, MA1
Adeyemi, WJ1
Alabi, QK1
Yang, LW1
Song, M1
Li, YL1
Liu, YP1
Liu, C1
Han, L1
Wang, ZH1
Xing, YQ1
Zhong, M1
Coccurello, R1
Nazio, F1
Rossi, C1
De Angelis, F1
Vacca, V1
Giacovazzo, G1
Procacci, P1
Magnaghi, V1
Ciavardelli, D1
Marinelli, S1
Meyers, A1
Liu, T1
Vachharajani, V1
Nemati, A1
Moghadam, RA1
Mazani, M1
Darvishi, A1
Haghighatdoost, F1
Jabbari, M1
Hariri, M1
Chen, DQ1
Cao, G1
Argyopoulos, CP1
Yu, H1
Su, W1
Chen, L1
Samuels, DC1
Zhuang, S1
Bayliss, GP1
Zhao, S1
Yu, XY1
Vaziri, ND1
Wang, M1
Liu, D1
Mao, JR1
Ma, SX1
Zhao, J1
Shang, YQ1
Kang, H1
Ye, F1
Cheng, XH1
Li, XR1
Zhang, L1
Meng, MX1
Guo, Y1
Zhao, YY1
Kalhori, Z1
Mehranjani, MS1
Azadbakht, M1
Shariatzadeh, MA1
Nicholas, DA1
Proctor, EA1
Agrawal, M1
Belkina, AC1
Van Nostrand, SC1
Panneerseelan-Bharath, L1
Jones, AR1
Raval, F1
Ip, BC1
Zhu, M1
Cacicedo, JM1
Habib, C1
Sainz-Rueda, N1
Persky, L1
Sullivan, PG1
Corkey, BE1
Apovian, CM1
Kern, PA1
Lauffenburger, DA1
Nikolajczyk, BS1
Zahradka, P1
Wright, B1
Weighell, W1
Blewett, H1
Baldwin, A1
O, K1
Guzman, RP1
Taylor, CG1
Berge, C1
Ramsvik, MS1
Bohov, P1
Skorve, J1
Orsal, E1
Halici, Z2
Bayir, Y2
Cadirci, E2
Bilen, H1
Ferah, I1
Aydin, A2
Ozkanlar, S1
Ayan, AK2
Seven, B1
Ozaltin, S1
Sue, YM1
Chou, HC2
Chang, CC2
Yang, NJ1
Chou, Y1
Juan, SH2
Aguer, C1
McCoin, CS1
Knotts, TA1
Thrush, AB1
Ono-Moore, K1
McPherson, R1
Dent, R1
Hwang, DH1
Adams, SH1
Harper, ME1
Khalatbari-Soltani, S1
Tabibi, H2
Rafraf, M1
Karimi, M1
Jafari, A1
Albayrak, A1
Polat, B1
Karakus, E1
Yildirim, OS1
Aksakal, AM1
Lee, BJ1
Lin, JS1
Lin, YC1
Lin, PT1
Mescka, CP1
Donida, B1
Marchetti, D1
Wayhs, CA1
Ribas, GS1
Dutra-Filho, CS1
Akbar, H1
Batistel, F1
Drackley, JK1
Loor, JJ1
Nishikawa, H1
Osaki, Y1
Jiang, F1
Wu, J1
Yu, L1
Liu, S1
Patterson, RE1
Kalavalapalli, S1
Williams, CM1
Nautiyal, M1
Mathew, JT1
Martinez, J1
Reinhard, MK1
McDougall, DJ1
Rocca, JR1
Yost, RA1
Cusi, K1
Garrett, TJ1
Sunny, NE1
Wen, LL1
Lin, CY1
Lo, HY1
Goldberg, EL1
Dixit, VD1
Arafa, HM1
Volek, JS2
Judelson, DA1
Silvestre, R1
Yamamoto, LM1
Spiering, BA1
Hatfield, DL1
Vingren, JL1
Quann, EE1
Anderson, JM1
Maresh, CM1
Kraemer, WJ1
Davis, PA1
Mormino, P1
Savica, V3
Calò, LA1
Ata, SM1
Vaishnav, U1
Puglisi, M1
Lofgren, IE1
Wood, RJ1
Fernandez, ML1
Derosa, G2
Maffioli, P2
Ferrari, I2
D'Angelo, A2
Fogari, E2
Palumbo, I2
Randazzo, S2
Cicero, AF2
Gürocak, S1
Yilmaz, A1
Alp, E1
Üre, I1
Sözen, S1
Menevşe, S1
Menevşe, A1
Bozkirli, I1
Hakeshzadeh, F1
Hedayati, M1
Malakoutian, T1
Bloom, DA1
Macciò, A1
Madeddu, C1
Gramignano, G1
Mulas, C1
Floris, C1
Sanna, E1
Cau, MC1
Panzone, F1
Mantovani, G1
Szefel, J1
Kruszewski, WJ1
Ciesielski, M1
Szajewski, M1
Kawecki, K1
Jankun, J1
Lysiak-Szydłowska, W1
Sampey, BP1
Freemerman, AJ1
Kuan, PF1
Galanko, JA1
O'Connell, TM1
Ilkayeva, OR1
Muehlbauer, MJ1
Stevens, RD1
Newgard, CB1
Brauer, HA1
Troester, MA1
Makowski, L1
Gorce-Dupuy, AM1
Vela, C1
Badiou, S1
Bargnoux, AS1
Josse, C1
Roagna, N1
Delage, M1
Michel, F1
Vernet, MH1
Destizons, D1
Cristol, JP1
Vicari, E2
La Vignera, S1
Calogero, AE1
Maeda, H1
Hirakata, H1
Calvani, M2
Benatti, P1
Santoro, D2
Monardo, P1
Peluso, G1
Bellinghieri, G2
Famularo, G1
De Simone, C1
Trinchieri, V1
Mosca, L1
Pertosa, G1
Grandaliano, G1
Simone, S1
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Schena, FP1
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Kroutil, M1
Jezdinsky, J1
Rotzsch, W1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Hemodialysis on Plasma Carnitine Levels in Patients With End Stage Renal Disease[NCT05817799]Phase 2/Phase 383 participants (Anticipated)Interventional2023-01-01Recruiting
Use of Acetyl L-Carnitine in Patients With Covid-19 Pneumonia[NCT04623619]100 participants (Anticipated)Interventional2020-12-15Not yet recruiting
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease[NCT05719714]Phase 1/Phase 260 participants (Anticipated)Interventional2023-11-01Recruiting
A Blinded, Randomized, Controlled Study to Examine the Bioavailability of Compounds From Different Bean Varieties in Healthy Individuals.[NCT02342340]8 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for carnitine and Innate Inflammatory Response

ArticleYear
The effects of L-carnitine supplementation on inflammatory and anti-inflammatory markers in adults: a systematic review and dose-response meta-analysis.
    Inflammopharmacology, 2023, Volume: 31, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Biomarkers; C-Reactive Protein; Carnitine; Dietary Su

2023
The Crosstalk between Prostate Cancer and Microbiota Inflammation: Nutraceutical Products Are Useful to Balance This Interplay?
    Nutrients, 2020, Aug-31, Volume: 12, Issue:9

    Topics: Acetylcysteine; Carnitine; Chronic Disease; Dietary Supplements; Disease Progression; Fatty Acids, U

2020
TMA/TMAO in Hypertension: Novel Horizons and Potential Therapies.
    Journal of cardiovascular translational research, 2021, Volume: 14, Issue:6

    Topics: Animals; Carnitine; Choline; Gastrointestinal Microbiome; Glucose; Humans; Hypertension; Inflammatio

2021
Preventive effect of l-carnitine and its derivatives on endothelial dysfunction and platelet aggregation.
    Clinical nutrition ESPEN, 2016, Volume: 15

    Topics: Acetylcarnitine; Animals; Antioxidants; Carnitine; Cell Adhesion; Cell Adhesion Molecules; Clinical

2016
The effect of L-carnitine on inflammatory mediators: a systematic review and meta-analysis of randomized clinical trials.
    European journal of clinical pharmacology, 2019, Volume: 75, Issue:8

    Topics: C-Reactive Protein; Carnitine; Dietary Supplements; Humans; Inflammation; Inflammation Mediators; In

2019
Inflammation and L-carnitine therapy in hemodialysis patients: a review.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:3

    Topics: C-Reactive Protein; Carnitine; Humans; Inflammation; Renal Dialysis; Serum Amyloid A Protein

2015
Liver Cirrhosis: Evaluation, Nutritional Status, and Prognosis.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Carcinoma, Hepatocellular; Carnitine; Electric Impedance; Fibrosis; Hand Strength; Hepatitis C, Chro

2015
[Hyporesponsiveness to recombinant human erythropoietin therapy in anemic patients on hemodialysis].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 6

    Topics: Aluminum; Anemia; Angiotensin-Converting Enzyme Inhibitors; Carnitine; Chronic Disease; Drug Resista

2004
Carnitine system in uremic patients: molecular and clinical aspects.
    Seminars in nephrology, 2004, Volume: 24, Issue:5

    Topics: Carnitine; Humans; Inflammation; Insulin Resistance; Renal Dialysis; Uremia

2004
Carnitines and its congeners: a metabolic pathway to the regulation of immune response and inflammation.
    Annals of the New York Academy of Sciences, 2004, Volume: 1033

    Topics: Animals; Carnitine; HIV Infections; Humans; Immunity, Mucosal; Inflammation; Rats; Systemic Inflamma

2004
Inflammation and endothelial dysfunction as therapeutic targets in patients with heart failure.
    International journal of cardiology, 2005, Apr-28, Volume: 100, Issue:3

    Topics: Animals; Apoptosis; Carnitine; Cell Adhesion Molecules; Endothelin-1; Endothelium, Vascular; Exercis

2005

Trials

13 trials available for carnitine and Innate Inflammatory Response

ArticleYear
Effect of L-Carnitine Supplementation on Inflammatory Markers and Serum Glucose in Hemodialysis Children: A Randomized, Placebo-Controlled Clinical Trial.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2022, Volume: 32, Issue:2

    Topics: Adolescent; Albumins; Biomarkers; Blood Glucose; C-Reactive Protein; Carnitine; Child; Dietary Suppl

2022
Effects of dietary lysolecithin on growth performance, serum biochemical indexes, antioxidant capacity, lipid metabolism and inflammation-related genes expression of juvenile large yellow croaker (Larimichthys crocea).
    Fish & shellfish immunology, 2022, Volume: 128

    Topics: Alanine Transaminase; Animal Feed; Animals; Antioxidants; Aspartate Aminotransferases; Carnitine; Ch

2022
Can L-Carnitine Supplementation Improve Cardiopulmonary Function? A Randomized Controlled Clinical Trial in Hemodialysis Patients.
    Iranian journal of kidney diseases, 2020, Volume: 14, Issue:6

    Topics: Carnitine; Dietary Supplements; Humans; Inflammation; Quality of Life; Renal Dialysis

2020
Effect of L-carnitine and conjugated linoleic acid supplements on haemoglobin levels and haptoglobin genotype in chronic kidney disease.
    JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69, Issue:3

    Topics: Adult; Anemia; C-Reactive Protein; Carnitine; Dietary Supplements; Ferritins; Genotype; Haptoglobins

2019
Effect of L-carnitine supplementation in comparison with moderate aerobic training on serum inflammatory parameters in healthy obese women.
    The Journal of sports medicine and physical fitness, 2015, Volume: 55, Issue:11

    Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Carnitine; Dietary Supplements; Double-Blind

2015
Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antioxidants; Biomarkers; C-Reactive Protein; Car

2015
Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults.
    The American journal of cardiology, 2008, Nov-15, Volume: 102, Issue:10

    Topics: Adult; Blood Vessels; Carnitine; Cross-Over Studies; Dietary Fats; Dietary Supplements; Double-Blind

2008
Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients.
    Endocrine journal, 2010, Volume: 57, Issue:9

    Topics: Anti-Obesity Agents; Body Weight; Carnitine; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy

2010
Comparison between orlistat plus l-carnitine and orlistat alone on inflammation parameters in obese diabetic patients.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:5

    Topics: Adiponectin; Anti-Inflammatory Agents; Anti-Obesity Agents; Blood Glucose; Body Mass Index; Body Wei

2011
Effects of l-carnitine supplement on serum amyloid A and vascular inflammation markers in hemodialysis patients: a randomized controlled trial.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2011, Volume: 21, Issue:6

    Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Carnitine; Dietary Supplements; Double-Blind Metho

2011
A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers: evaluating the impact on metabolic and inflammatory profiles and quality of life.
    Gynecologic oncology, 2012, Volume: 124, Issue:3

    Topics: Adult; Aged; Antioxidants; Cachexia; Carnitine; Celecoxib; Female; Genital Neoplasms, Female; Humans

2012
Antioxidant treatment with carnitines is effective in infertile patients with prostatovesiculoepididymitis and elevated seminal leukocyte concentrations after treatment with nonsteroidal anti-inflammatory compounds.
    Fertility and sterility, 2002, Volume: 78, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carnitine; Epididymitis; Female; Genit

2002
[Antioxidant therapeutic efficiency after the use of carnitine in infertile patients with bacterial or non bacterial prostato-vesiculo-epididymitis].
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2001, Volume: 73, Issue:1

    Topics: Adult; Antioxidants; Carnitine; Epididymitis; Humans; Infertility, Male; Inflammation; Male; Prostat

2001

Other Studies

59 other studies available for carnitine and Innate Inflammatory Response

ArticleYear
l-carnitine modulates autophagy, oxidative stress and inflammation in trazodone induced testicular toxicity.
    Life sciences, 2022, Feb-01, Volume: 290

    Topics: Animals; Antioxidants; Autophagy; Carnitine; Inflammation; Lipid Peroxidation; Male; Oxidative Stres

2022
Effect of l-carnitine supplementation on lead acetate-induced liver cell apoptosis and inflammation: role of caspase-3 and glycogen synthase kinase-3β enzymes.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Carnitine; Caspase 3; Dietary Supplement

2022
Association Between Plasma L-Carnitine and Cognitive Impairment in Patients with Acute Ischemic Stroke.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 86, Issue:1

    Topics: Brain Ischemia; Carnitine; Cognitive Dysfunction; Humans; Inflammation; Ischemic Stroke; Prospective

2022
Neuroprotective effect of mildronate and L-carnitine on the cognitive parameters of aged mice and mice with LPS-induced inflammation.
    Metabolic brain disease, 2022, Volume: 37, Issue:7

    Topics: Animals; Carnitine; Cognition; DNA, Mitochondrial; Fatty Acids; Glucose; Inflammation; Lipopolysacch

2022
Carnitine Protects against MPP
    Cells, 2022, 09-01, Volume: 11, Issue:17

    Topics: 1-Methyl-4-phenylpyridinium; Acetylcarnitine; Apoptosis; Carnitine; Cell Line, Tumor; Dopaminergic N

2022
β-Hydroxyphosphocarnitine modifies fibrosis, steatosis and improves liver function in non-alcoholic steatohepatitis induced in rats.
    BMC pharmacology & toxicology, 2022, 09-29, Volume: 23, Issue:1

    Topics: Animals; Carnitine; Cholesterol; Diet, High-Fat; Disease Models, Animal; Fructose; Glucose; Glycogen

2022
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation

2022
    Food & function, 2023, Jan-23, Volume: 14, Issue:2

    Topics: Animals; Ascophyllum; Betaine; Carnitine; Fatty Acids, Volatile; Gastrointestinal Microbiome; Inflam

2023
L-carnitine Modulates Cognitive Impairment Induced by Doxorubicin and Cyclophosphamide in Rats; Insights to Oxidative Stress, Inflammation, Synaptic Plasticity, Liver/brain, and Kidney/brain Axes.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2023, Volume: 18, Issue:3

    Topics: Acetylcholinesterase; Animals; Antioxidants; Brain; Carnitine; Cognitive Dysfunction; Cyclophosphami

2023
Anti-acne activity of carnitine salicylate and magnolol through the regulation of exfoliation, lipogenesis, bacterial growth and inflammation.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2023, Volume: 29, Issue:7

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Carnitine; Humans; Inflammation; Lignans; Lipogenesis; Salicyl

2023
L-carnitine regulated Nrf2/Keap1 activation in vitro and in vivo and protected oxidized fish oil-induced inflammation response by inhibiting the NF-κB signaling pathway in Rhynchocypris lagowski Dybowski.
    Fish & shellfish immunology, 2019, Volume: 93

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carnitine; Carrier Proteins; Cell Line; Cyprinidae;

2019
Effect of high-fat diet on peripheral blood mononuclear cells and adipose tissue in early stages of diet-induced weight gain.
    The British journal of nutrition, 2019, 12-28, Volume: 122, Issue:12

    Topics: Animals; Autophagy; Carnitine; Diet, High-Fat; Homeostasis; Inflammation; Insulin; Insulin Resistanc

2019
Protective effects of olmesartan and l-carnitine on doxorubicin-induced cardiotoxicity in rats.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Cardiotoxicity; Carnitine; Creatine Kinase, MB Form; Doxorubicin;

2020
Stimulating pyruvate dehydrogenase complex reduces itaconate levels and enhances TCA cycle anabolic bioenergetics in acutely inflamed monocytes.
    Journal of leukocyte biology, 2020, Volume: 107, Issue:3

    Topics: Algorithms; Amino Acids; Carnitine; Citric Acid Cycle; Cytokines; Energy Metabolism; Humans; Inflamm

2020
Fatty Acid and Carnitine Metabolism Are Dysregulated in Systemic Sclerosis Patients.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adult; Aged; Carnitine; Cohort Studies; Cytokines; Dendritic Cells; Etoposide; Fatty Acids; Female;

2020
Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones.
    Metabolomics : Official journal of the Metabolomic Society, 2020, 09-07, Volume: 16, Issue:9

    Topics: Amino Acids; Animals; Biomarkers; Carnitine; Estradiol; Glycerophospholipids; Glycine; Gonadal Stero

2020
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adult; Bacteria; Bacterial Proteins; Biomarkers; Carnitine; Common Variable Immunodeficiency; Diet;

2020
Non-targeted metabolomics analyses by mass spectrometry to explore metabolic stress after six training weeks in high level swimmers.
    Journal of sports sciences, 2021, Volume: 39, Issue:9

    Topics: Adolescent; Athletes; Butyric Acid; Carnitine; Cresols; Cross-Over Studies; Fatigue; Female; Glycoge

2021
A Novel Formulation of Glucose-Sparing Peritoneal Dialysis Solutions with l-Carnitine Improves Biocompatibility on Human Mesothelial Cells.
    International journal of molecular sciences, 2020, Dec-24, Volume: 22, Issue:1

    Topics: Bicarbonates; Biocompatible Materials; Carnitine; Cell Survival; Cytokines; Dialysis Solutions; Epit

2020
Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation.
    Scientific reports, 2021, 03-05, Volume: 11, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Carnitine; Choline; Cross-Sectional Studies; Fatty Acids; Female; Human

2021
L-Carnitine Tartrate Downregulates the ACE2 Receptor and Limits SARS-CoV-2 Infection.
    Nutrients, 2021, Apr-14, Volume: 13, Issue:4

    Topics: Adult; Aged; Angiotensin-Converting Enzyme 2; Animals; Carnitine; Cell Line; Cell Survival; COVID-19

2021
Effects of high-flux hemodialysis combined with levocarnitine on blood lipid metabolism, calcium and phosphorus metabolism, iPTH, cardiac function and inflammation of uremic patients.
    Minerva medica, 2023, Volume: 114, Issue:2

    Topics: Calcium; Carnitine; Humans; Inflammation; Lipid Metabolism; Parathyroid Hormone; Phosphorus; Renal D

2023
Protective effects of L-carnitine on behavioral alterations and neuroinflammation in striatum of glutaryl-COA dehydrogenase deficient mice.
    Archives of biochemistry and biophysics, 2021, 09-30, Volume: 709

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Carnitine; Cathepsin D; Co

2021
Combined hyperosmolarity and inflammatory conditions in stressed human corneal epithelial cells and macrophages to evaluate osmoprotective agents as potential DED treatments.
    Experimental eye research, 2021, Volume: 211

    Topics: Animals; Apoptosis; Betaine; Carnitine; Cell Survival; Cells, Cultured; Dry Eye Syndromes; Epitheliu

2021
Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome.
    Hormone molecular biology and clinical investigation, 2018, Apr-18, Volume: 35, Issue:2

    Topics: Adult; Aged; Biomarkers; Carnitine; Choline; Female; Humans; Inflammation; Male; Metabolic Syndrome;

2018
Combined but not single administration of vitamin C and l-carnitine ameliorates cisplatin-induced gastric mucosa damage in male rats.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:8

    Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Body Weight; Carnitine; Cell Count; Cisplatin; Cyt

2018
L-Carnitine inhibits the senescence-associated secretory phenotype of aging adipose tissue by JNK/p53 pathway.
    Biogerontology, 2019, Volume: 20, Issue:2

    Topics: Adipose Tissue; Aging; Animals; Carnitine; Cellular Senescence; Inflammation; MAP Kinase Signaling S

2019
Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Amino Acids; AMP-Activated Protein Kinases; Animals; Autophagy

2018
Frontline Science: Monocytes sequentially rewire metabolism and bioenergetics during an acute inflammatory response.
    Journal of leukocyte biology, 2019, Volume: 105, Issue:2

    Topics: Amino Acids; Carbohydrate Metabolism; Carnitine; Energy Metabolism; Humans; Inflammation; Lipid Meta

2019
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
    Nature communications, 2019, 04-01, Volume: 10, Issue:1

    Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disea

2019
L-Carnitine improves endocrine function and folliculogenesis by reducing inflammation, oxidative stress and apoptosis in mice following induction of polycystic ovary syndrome.
    Reproduction, fertility, and development, 2019, Volume: 31, Issue:2

    Topics: Animals; Apoptosis; Carnitine; Disease Models, Animal; Female; Follicle Stimulating Hormone; Inflamm

2019
Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.
    Cell metabolism, 2019, 09-03, Volume: 30, Issue:3

    Topics: Adult; Aged; Carnitine; Carnitine O-Palmitoyltransferase; Cells, Cultured; Cross-Sectional Studies;

2019
Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease.
    Atherosclerosis, 2013, Volume: 230, Issue:2

    Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carnitine; Carotid Steno

2013
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation.
    Lipids in health and disease, 2013, Oct-07, Volume: 12

    Topics: Adipose Tissue; Animals; Carnitine; Caseins; Chronic Disease; Diet, High-Fat; Fatty Acids, Omega-3;

2013
The role of carnitine on ovariectomy and inflammation-induced osteoporosis in rats.
    Experimental biology and medicine (Maywood, N.J.), 2013, Volume: 238, Issue:12

    Topics: Absorptiometry, Photon; Animals; Bone Density; Carnitine; Female; Inflammation; Interleukin-1; Inter

2013
L-carnitine protects against carboplatin-mediated renal injury: AMPK- and PPARα-dependent inactivation of NFAT3.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Apoptosis; Carboplatin; Carnitine; Cycl

2014
Acylcarnitines: potential implications for skeletal muscle insulin resistance.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:1

    Topics: Adult; Animals; Antioxidants; Carnitine; Case-Control Studies; Cell Line; Cells, Cultured; Cytokines

2015
Treatment with Carnitine Enhances Bone Fracture Healing under Osteoporotic and/or Inflammatory Conditions.
    Basic & clinical pharmacology & toxicology, 2015, Volume: 117, Issue:3

    Topics: Absorptiometry, Photon; Animals; Bone Density; Carnitine; Disease Models, Animal; Female; Fracture H

2015
Investigation of inflammatory profile in MSUD patients: benefit of L-carnitine supplementation.
    Metabolic brain disease, 2015, Volume: 30, Issue:5

    Topics: Carnitine; Child; Child, Preschool; Dietary Supplements; Female; Humans; Inflammation; Inflammation

2015
Alterations in Hepatic FGF21, Co-Regulated Genes, and Upstream Metabolic Genes in Response to Nutrition, Ketosis and Inflammation in Peripartal Holstein Cows.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Angiopoietins; Animal Nutritional Physiological Phenomena; Animals; Carnitine; Cattle; Circadian Rhy

2015
L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPARγ signaling.
    Molecular medicine reports, 2016, Volume: 13, Issue:2

    Topics: Animals; Cachexia; Carnitine; Carnitine O-Palmitoyltransferase; Cyclooxygenase 2; Gene Expression Re

2016
Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity.
    American journal of physiology. Endocrinology and metabolism, 2016, Apr-01, Volume: 310, Issue:7

    Topics: Animals; Carbon Isotopes; Carnitine; Ceramides; Chromatography, Liquid; Citric Acid Cycle; Dietary F

2016
Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Acetylation; Alkanesulfonic Acids; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Car

2016
Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation.
    Molecular metabolism, 2017, Volume: 6, Issue:2

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Adipose Tissue; Animals; Carnitine; Carnitine O-Acetyltransferas

2017
Carnitine deficiency aggravates carboplatin nephropathy through deterioration of energy status, oxidant/anti-oxidant balance, and inflammatory endocoids.
    Toxicology, 2008, Dec-05, Volume: 254, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Blood Urea Nitrogen; Carboplatin; Carnitine; Creatini

2008
L-carnitine, inflammation and hypertension.
    Nephrology (Carlton, Vic.), 2009, Volume: 14, Issue:2

    Topics: Carnitine; Heme Oxygenase-1; Humans; Hypertension; Inflammation; NG-Nitroarginine Methyl Ester

2009
Macronutrient composition and increased physical activity modulate plasma adipokines and appetite hormones during a weight loss intervention.
    Journal of women's health (2002), 2010, Volume: 19, Issue:1

    Topics: Adipokines; Adult; Appetite Regulation; Body Composition; Body Mass Index; Carnitine; Diet, Reducing

2010
Inflammation and oxidative stress in testicular torsion: do they deserve intensive treatment to save both guilty and innocent testes?
    Urology, 2011, Volume: 78, Issue:1

    Topics: Animals; Antioxidants; Carnitine; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Inflammation

2011
Re: Gurocak et al.: Inflammation and oxidative stress in testicular torsion: do they deserve intensive treatment to save both guilty and innocent testes? (Urology 2011;78:164-169).
    Urology, 2011, Volume: 78, Issue:5

    Topics: Animals; Antioxidants; Carnitine; Cyclooxygenase Inhibitors; Inflammation; Male; Oxidative Stress; S

2011
L-carnitine and cancer cachexia. II. Effects of lipid emulsion used in total parenteral nutrition on parameters of hemostasis and inflammatory state in L-carnitine deficiency in myocytes.
    Oncology reports, 2012, Volume: 28, Issue:1

    Topics: Aged; Body Mass Index; Cachexia; Carnitine; Fat Emulsions, Intravenous; Female; Hemostasis; Humans;

2012
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Adipose Tissue; Amino Acids; Analysis of Variance; Animals; Biomarkers; Blotting, Western; Carnitine

2012
Antioxidant and oligonutrient status, distribution of amino acids, muscle damage, inflammation, and evaluation of renal function in elite rugby players.
    Clinical chemistry and laboratory medicine, 2012, Oct-01, Volume: 50, Issue:10

    Topics: Adult; Amino Acids; Antioxidants; Athletes; Carnitine; Female; Follow-Up Studies; Football; Glomerul

2012
Role of carnitine in modulating acute-phase protein synthesis in hemodialysis patients.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2005, Volume: 15, Issue:1

    Topics: Acute-Phase Proteins; C-Reactive Protein; Carnitine; Energy Metabolism; Hemoglobins; Humans; Inflamm

2005
Inflammation and carnitine in hemodialysis patients.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2005, Volume: 15, Issue:1

    Topics: Atherosclerosis; Carnitine; Chemokine CCL2; Humans; Inflammation; Interleukin-6; JNK Mitogen-Activat

2005
Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient Mdx mice.
    The American journal of pathology, 2007, Volume: 170, Issue:2

    Topics: Animals; Apoptosis; Calcium; Carnitine; Creatine Kinase; Diaphragm; Dystroglycans; Dystrophin; Free

2007
Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-deficient jvs (OCTN2(-/-)) mice.
    Molecular genetics and metabolism, 2007, Volume: 92, Issue:4

    Topics: Amino Acid Transport Systems; Animals; Atrophy; Carnitine; Colon; Crohn Disease; Disease Models, Ani

2007
The influence of inflammation of the human male genital tract on secretion of the seminal markers alpha-glucosidase, glycerophosphocholine, carnitine, fructose and citric acid.
    International journal of andrology, 1990, Volume: 13, Issue:5

    Topics: Adolescent; Adult; alpha-Glucosidases; Analysis of Variance; Carnitine; Citrates; Citric Acid; Epidi

1990
Changes in carnitine in polymorphonuclear leukocytes, mononuclear cells, and plasma from patients with inflammatory disorders.
    Clinical chemistry, 1988, Volume: 34, Issue:1

    Topics: Adult; Aged; Brain Injuries; Carnitine; Female; Humans; Infections; Inflammation; Leukocytes, Mononu

1988
[Effects of thyroxine and carnitines on the experimental inflammations].
    Acta biologica et medica Germanica, 1967, Volume: 19, Issue:5

    Topics: Animals; Carnitine; Collagen; Edema; Exudates and Transudates; Foreign Bodies; Granulation Tissue; H

1967