Page last updated: 2024-10-16

carnitine and Hypotension

carnitine has been researched along with Hypotension in 12 studies

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"We conducted electronic searches in PubMed, Embase and Cochrane Central Register of Controlled Trials from January 1960 to 19th November 2021 to identify randomized controlled studies (RCTs), which examined the effects of oral or intravenous levocarnitine (L-carnitine) on dialysis-related hypotension among hemodialysis patients."9.22The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis. ( Cellini, J; Chewcharat, A; Chewcharat, P; Liu, W; Melendez Young, JA; Nigwekar, SU; Phipps, EA, 2022)
"L-Carnitine is an endogenous compound thought to be helpful in treating patients with dialysis-related hypotension and muscle cramps; however, sufficient evidence for these indications is lacking."8.84Effects of L-carnitine on dialysis-related hypotension and muscle cramps: a meta-analysis. ( Berlin, JA; Brunelli, SM; Feldman, HI; Flory, J; Lynch, KE; Rowan, CG, 2008)
"Intradialytic hypotension is common complication in stage 5 chronic kidney disease patients on hemodialysis."6.84Levocarnitine Decreases Intradialytic Hypotension Episodes: A Randomized Controlled Trial. ( Atilano-Díaz, A; Castillo-Torres, SA; Cruz-Valdez, J; Cuellar-Monterrubio, JE; Del Cueto-Aguilera, Á; Delgado-García, GR; Gallegos-Arguijo, DA; Ibarra-Sifuentes, HR; Martínez-Granados, RJ; Martínez-Guevara, EJ; Martínez-Jiménez, JG; Ortiz-Treviño, JF; Pezina-Cantú, CO; Sánchez-Martínez, C; Vera-Pineda, R, 2017)
"Carnitine plays a crucial role in the metabolism of fatty acids as well as energy production."5.72Evaluation of the relationship between serum carnitine levels and intradialytic complications in children with kidney failure. ( Abbasi, A; Askarian, F; Bakhtiari Koohsorkhi, M; Bazargani, B; Fahimi, D; Moghtaderi, M; Mojtahedi, SY; Samimi, M, 2022)
"We conducted electronic searches in PubMed, Embase and Cochrane Central Register of Controlled Trials from January 1960 to 19th November 2021 to identify randomized controlled studies (RCTs), which examined the effects of oral or intravenous levocarnitine (L-carnitine) on dialysis-related hypotension among hemodialysis patients."5.22The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis. ( Cellini, J; Chewcharat, A; Chewcharat, P; Liu, W; Melendez Young, JA; Nigwekar, SU; Phipps, EA, 2022)
"L-Carnitine is an endogenous compound thought to be helpful in treating patients with dialysis-related hypotension and muscle cramps; however, sufficient evidence for these indications is lacking."4.84Effects of L-carnitine on dialysis-related hypotension and muscle cramps: a meta-analysis. ( Berlin, JA; Brunelli, SM; Feldman, HI; Flory, J; Lynch, KE; Rowan, CG, 2008)
"Intradialytic hypotension is common complication in stage 5 chronic kidney disease patients on hemodialysis."2.84Levocarnitine Decreases Intradialytic Hypotension Episodes: A Randomized Controlled Trial. ( Atilano-Díaz, A; Castillo-Torres, SA; Cruz-Valdez, J; Cuellar-Monterrubio, JE; Del Cueto-Aguilera, Á; Delgado-García, GR; Gallegos-Arguijo, DA; Ibarra-Sifuentes, HR; Martínez-Granados, RJ; Martínez-Guevara, EJ; Martínez-Jiménez, JG; Ortiz-Treviño, JF; Pezina-Cantú, CO; Sánchez-Martínez, C; Vera-Pineda, R, 2017)
"L-carnitine treatment was associated with a significant drop in pre-dialysis concentrations of serum urea nitrogen, creatinine and phosphorus (means +/- SEM, 101 +/- 4."2.67Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. ( Ahmad, S; Ashbrook, DW; Golper, TA; Hirschberg, R; Katz, LA; Kopple, JD; Kurtin, P; Nicora, R; Robertson, HT; Wolfson, M, 1990)
"Carnitine plays a crucial role in the metabolism of fatty acids as well as energy production."1.72Evaluation of the relationship between serum carnitine levels and intradialytic complications in children with kidney failure. ( Abbasi, A; Askarian, F; Bakhtiari Koohsorkhi, M; Bazargani, B; Fahimi, D; Moghtaderi, M; Mojtahedi, SY; Samimi, M, 2022)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's5 (41.67)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Bazargani, B1
Mojtahedi, SY1
Fahimi, D1
Askarian, F1
Moghtaderi, M1
Abbasi, A1
Samimi, M1
Bakhtiari Koohsorkhi, M1
Chewcharat, A1
Chewcharat, P1
Liu, W1
Cellini, J1
Phipps, EA1
Melendez Young, JA1
Nigwekar, SU1
Ibarra-Sifuentes, HR1
Del Cueto-Aguilera, Á1
Gallegos-Arguijo, DA1
Castillo-Torres, SA1
Vera-Pineda, R1
Martínez-Granados, RJ1
Atilano-Díaz, A1
Cuellar-Monterrubio, JE1
Pezina-Cantú, CO1
Martínez-Guevara, EJ1
Ortiz-Treviño, JF1
Delgado-García, GR1
Martínez-Jiménez, JG1
Cruz-Valdez, J1
Sánchez-Martínez, C1
Scrace, B1
Wilson, P1
Pappachan, J1
Lynch, KE1
Feldman, HI1
Berlin, JA1
Flory, J1
Rowan, CG1
Brunelli, SM1
Eknoyan, G1
Latos, DL1
Lindberg, J1
Handelman, GJ1
Riley, S1
Rutherford, S1
Rutherford, PA1
Perazella, MA1
Kobayakawa, H1
Shinzato, T1
Maeda, K1
Ahmad, S1
Robertson, HT1
Golper, TA1
Wolfson, M1
Kurtin, P1
Katz, LA1
Hirschberg, R1
Nicora, R1
Ashbrook, DW1
Kopple, JD1
Cederblad, G1
Niklasson, A1
Rydgren, B1
Albertsson-Wikland, K1
Olegård, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Carnitine Deficiency and Benefits of Its Supplementation in Pediatric Hemodialysis Patients[NCT05948124]Early Phase 140 participants (Anticipated)Interventional2023-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for carnitine and Hypotension

ArticleYear
The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis.
    PloS one, 2022, Volume: 17, Issue:7

    Topics: Carnitine; Dietary Supplements; Humans; Hypotension; Muscle Cramp; Renal Dialysis

2022
Effects of L-carnitine on dialysis-related hypotension and muscle cramps: a meta-analysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:5

    Topics: Carnitine; Humans; Hypotension; Muscle Cramp; Renal Dialysis

2008
Practice recommendations for the use of L-carnitine in dialysis-related carnitine disorder. National Kidney Foundation Carnitine Consensus Conference.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:4

    Topics: Anemia; Carnitine; Fatigue; Homeostasis; Humans; Hypotension; Kidney; Kidney Failure, Chronic; Renal

2003
Debate forum: carnitine supplements have not been demonstrated as effective in patients on long-term dialysis therapy.
    Blood purification, 2006, Volume: 24, Issue:1

    Topics: Anemia; Carnitine; Drug Resistance; Erythropoietin; Fatigue; Hypotension; Randomized Controlled Tria

2006
Pharmacologic options available to treat symptomatic intradialytic hypotension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:4 Suppl 4

    Topics: Adrenergic Agents; Autonomic Nervous System; Caffeine; Carnitine; Ephedrine; Fludrocortisone; Hemodi

2001

Trials

3 trials available for carnitine and Hypotension

ArticleYear
Levocarnitine Decreases Intradialytic Hypotension Episodes: A Randomized Controlled Trial.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2017, Volume: 21, Issue:5

    Topics: Adult; Carnitine; Double-Blind Method; Female; Humans; Hypotension; Kidney Failure, Chronic; Male; M

2017
Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects.
    Kidney international, 1990, Volume: 38, Issue:5

    Topics: Carnitine; Double-Blind Method; Exercise; Female; Humans; Hypotension; Kidney Failure, Chronic; Male

1990
Carnitine in maternal and neonatal plasma.
    Acta paediatrica Scandinavica, 1985, Volume: 74, Issue:4

    Topics: 3-Hydroxybutyric Acid; Carnitine; Cesarean Section; Fatty Acids, Nonesterified; Female; Glucose; Hum

1985

Other Studies

4 other studies available for carnitine and Hypotension

ArticleYear
Evaluation of the relationship between serum carnitine levels and intradialytic complications in children with kidney failure.
    Pediatric nephrology (Berlin, Germany), 2022, Volume: 37, Issue:9

    Topics: Adolescent; Cardiomyopathies; Carnitine; Child; Humans; Hyperammonemia; Hypotension; Kidney Failure,

2022
Medium chain acyl CoA dehydrogenase deficiency causes unexplained coma in a 10-year-old child.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:12

    Topics: Acyl-CoA Dehydrogenase; Ammonia; Carnitine; Child; Coma; Critical Care; Emergency Medical Services;

2008
Low carnitine levels in hemodialysis patients: relationship with functional activity status and intra-dialytic hypotension.
    Clinical nephrology, 1997, Volume: 48, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carnitine; Female; Humans; Hypotension; Male; Middle Aged; Renal Dia

1997
[Dialysis-associated disequilibrium syndrome and the prevention and therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50 Suppl

    Topics: Animals; Autonomic Nervous System Diseases; Brain Edema; Carnitine; Humans; Hyponatremia; Hypotensio

1992