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carnitine and Hyperthyroidism

carnitine has been researched along with Hyperthyroidism in 25 studies

Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.

Research Excerpts

ExcerptRelevanceReference
"Old studies in animals and unblinded studies in a few hyperthyroid patients suggested that L -carnitine is a periferal antagonist of thyroid hormone action at least in some tissues."9.09Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. ( Benvenga, S; Campenni, A; Lapa, D; Ruggeri, RM; Russo, A; Trimarchi, F, 2001)
"Weakness is common in both hyper- and hypothyroidism, and skeletal muscle L-carnitine may play a role in this regard, as suggested by studies indicating abnormal levels of carnitine in serum and urine of patients with thyroid dysfunction."7.73Muscle carnitine in hypo- and hyperthyroidism. ( Gilchrist, JM; Hennessey, JV; Kandula, M; Sinclair, C, 2005)
"The effect of hyperthyroidism on fatty acid oxidation and on carnitine-acylcarnitine translocase activity in rat heart mitochondria has been studied."7.69Stimulation of carnitine acylcarnitine translocase activity in heart mitochondria from hyperthyroid rats. ( Paradies, G; Petrosillo, G; Quagliariello, E; Ruggiero, FM, 1996)
" Cardiac sarcoplasmic reticulum (SR) was isolated at several time points during the induction of the hyperthyroid state and calcium transport and the levels of carnitine derivatives were determined."7.67Sarcoplasmic reticulum Ca2+ transport and long chain acylcarnitines in hyperthyroidism. ( Black, SC; Katz, S; McNeill, JH, 1988)
"Urinary excretion of carnitine and serum concentrations of carnitine, triglyceride, and free fatty acids were measured in 54 hyperthyroid and 13 hypothyroid patients, and the results were compared with those of normal subjects."7.65Urinary excretion of carnitine in patients with hyperthyroidism and hypothyroidism: augmentation by thyroid hormone. ( Imamura, A; Kawamura, N; Maebashi, M; Sato, M; Yoshinaga, K, 1977)
"By experiments on cells (neurons, hepatocytes, and fibroblasts) that are targets for thyroid hormones and a randomized clinical trial on iatrogenic hyperthyroidism, we validated the concept that L-carnitine is a peripheral antagonist of thyroid hormone action."6.21Effects of carnitine on thyroid hormone action. ( Amato, A; Benvenga, S; Calvani, M; Trimarchi, F, 2004)
"Old studies in animals and unblinded studies in a few hyperthyroid patients suggested that L -carnitine is a periferal antagonist of thyroid hormone action at least in some tissues."5.09Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. ( Benvenga, S; Campenni, A; Lapa, D; Ruggeri, RM; Russo, A; Trimarchi, F, 2001)
"To examine acylcarnitine profiles in individuals with hypo- or hyperthyroidism, and determine whether any atypical acylcarnitine species identified would normalize with correction of thyroid status."3.79Acylcarnitine profile in thyroid disease. ( Dahl, M; Hannah-Shmouni, F; Mattman, A; Sinclair, G; Sirrs, S; Wong, S, 2013)
"Weakness is common in both hyper- and hypothyroidism, and skeletal muscle L-carnitine may play a role in this regard, as suggested by studies indicating abnormal levels of carnitine in serum and urine of patients with thyroid dysfunction."3.73Muscle carnitine in hypo- and hyperthyroidism. ( Gilchrist, JM; Hennessey, JV; Kandula, M; Sinclair, C, 2005)
"The effect of hyperthyroidism on fatty acid oxidation and on carnitine-acylcarnitine translocase activity in rat heart mitochondria has been studied."3.69Stimulation of carnitine acylcarnitine translocase activity in heart mitochondria from hyperthyroid rats. ( Paradies, G; Petrosillo, G; Quagliariello, E; Ruggiero, FM, 1996)
"Starvation (48 h) decreases fructose 2,6-bisphosphate (Fru-2,6-P2) concentrations and the ratio of free to acylated carnitine in hearts of euthyroid rats."3.68Mechanisms regulating cardiac fuel selection in hyperthyroidism. ( Fryer, LG; Holness, MJ; Kruszynska, YT; Liu, YL; Smith, DM; Sugden, MC, 1992)
" Cardiac sarcoplasmic reticulum (SR) was isolated at several time points during the induction of the hyperthyroid state and calcium transport and the levels of carnitine derivatives were determined."3.67Sarcoplasmic reticulum Ca2+ transport and long chain acylcarnitines in hyperthyroidism. ( Black, SC; Katz, S; McNeill, JH, 1988)
" Flux through carnitine palmitoyltransferase 1 was increased, consistent with the effects of hyperthyroidism on enzyme activity demonstrated in vitro."3.67The relationship between fat synthesis and oxidation in the liver after re-feeding and its regulation by thyroid hormone. ( French, TJ; Holness, MJ; Schofield, PS; Sugden, MC, 1987)
"Urinary excretion of carnitine and serum concentrations of carnitine, triglyceride, and free fatty acids were measured in 54 hyperthyroid and 13 hypothyroid patients, and the results were compared with those of normal subjects."3.65Urinary excretion of carnitine in patients with hyperthyroidism and hypothyroidism: augmentation by thyroid hormone. ( Imamura, A; Kawamura, N; Maebashi, M; Sato, M; Yoshinaga, K, 1977)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199016 (64.00)18.7374
1990's3 (12.00)18.2507
2000's3 (12.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohba, K1
Sinha, RA1
Singh, BK1
Iannucci, LF1
Zhou, J1
Kovalik, JP1
Liao, XH1
Refetoff, S1
Sng, JCG1
Leow, MK1
Yen, PM1
Nordio, M1
Wong, S1
Hannah-Shmouni, F1
Sinclair, G1
Sirrs, S1
Dahl, M1
Mattman, A1
STRACK, E6
WORATZ, G1
ROTZSCH, W5
AURICH, H1
BLOESCHE, H1
BEMM, H2
Benvenga, S2
Amato, A1
Calvani, M1
Trimarchi, F2
Sinclair, C1
Gilchrist, JM1
Hennessey, JV1
Kandula, M1
Paradies, G1
Ruggiero, FM1
Petrosillo, G1
Quagliariello, E1
Ruggeri, RM1
Russo, A1
Lapa, D1
Campenni, A1
Mitchell, ME1
Reinwein, D1
Maebashi, M1
Kawamura, N2
Sato, M1
Imamura, A1
Yoshinaga, K2
Sugden, MC2
Holness, MJ2
Liu, YL1
Smith, DM1
Fryer, LG1
Kruszynska, YT1
Kaminsky, P1
Franck, P1
Jacob, JL1
Klein, M1
Nabet, P1
Duc, M1
Black, SC1
McNeill, JH1
Katz, S1
French, TJ1
Schofield, PS1
Emmrich, R1
Nolte, J1
Pette, D1
Bachmaier, B1
Kiefhaber, P1
Schneider, H1
Scriba, PC1
Maebashi, S1
Saito, S1
Sakurada, T1
Sliwowski, A1
Nitzschner, H1
Liebsch, F1
Willgerodt, H1

Reviews

3 reviews available for carnitine and Hyperthyroidism

ArticleYear
Effects of carnitine on thyroid hormone action.
    Annals of the New York Academy of Sciences, 2004, Volume: 1033

    Topics: Bone Density; Carnitine; Female; Humans; Hyperthyroidism; Osteoporosis; Randomized Controlled Trials

2004
Carnitine metabolism in human subjects. III. Metabolism in disease.
    The American journal of clinical nutrition, 1978, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Animals; Carnitine; Carnitine Acyltransferases; Child; Diabetes Mellitus; Diabeti

1978
[Advances in endocrinology. New data on thyrocaltitonin].
    Polskie Archiwum Medycyny Wewnetrznej, 1967, Volume: 39, Issue:2

    Topics: Calcitonin; Carnitine; Hyperthyroidism

1967

Trials

2 trials available for carnitine and Hyperthyroidism

ArticleYear
Effects of carnitine on thyroid hormone action.
    Annals of the New York Academy of Sciences, 2004, Volume: 1033

    Topics: Bone Density; Carnitine; Female; Humans; Hyperthyroidism; Osteoporosis; Randomized Controlled Trials

2004
Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Administration, Oral; Adult; Asthenia; Biomarkers; Body Weight; Bone Density; Carnitine; Double-Blin

2001

Other Studies

21 other studies available for carnitine and Hyperthyroidism

ArticleYear
Changes in Hepatic TRĪ² Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.
    Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:6

    Topics: Adipogenesis; Animals; Body Weight; Carnitine; Chronic Disease; Disease Models, Animal; Gene Express

2017
A novel treatment for subclinical hyperthyroidism: a pilot study on the beneficial effects of l-carnitine and selenium.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Carnitine; Female; Humans; Hyperthyroidism; Male; Middle Aged; Pilot Projects; Qu

2017
Acylcarnitine profile in thyroid disease.
    Clinical biochemistry, 2013, Volume: 46, Issue:1-2

    Topics: Adult; Aged; Carnitine; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Referenc

2013
[Effects of carnitine in hyperfunction of the thyroid gland].
    Endokrinologie, 1959, Volume: 38

    Topics: Carnitine; Endocrine System Diseases; Folic Acid; Humans; Hyperthyroidism; Viscera; Vitamin B Comple

1959
[Effect of L-carnitine on the vitamin B content of the skeletal muscles of normal and hyperthyroid rats].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1962, Jun-20, Volume: 328

    Topics: Animals; Carnitine; Folic Acid; Hyperthyroidism; Muscle, Skeletal; Muscles; Rats; Vitamin B Complex;

1962
[Use of L-carnitine in hyperfunction of the thyroid gland].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1962, Volume: 21

    Topics: Carnitine; Endocrine System Diseases; Folic Acid; Humans; Hyperthyroidism; Musculoskeletal Diseases;

1962
[TRIMETHYLAMINE AND TRIMETHYLAMINE OXIDE IN THE URINE AFTER THE ADMINISTRATION OF N-14- AND N-15-(-) CARNITINE].
    Acta biologica et medica Germanica, 1963, Volume: 11

    Topics: Amines; Body Fluids; Carnitine; Folic Acid; Humans; Hyperthyroidism; Male; Methylamines; Nitrogen; P

1963
Muscle carnitine in hypo- and hyperthyroidism.
    Muscle & nerve, 2005, Volume: 32, Issue:3

    Topics: Adult; Biopsy; Carnitine; Down-Regulation; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Mi

2005
Stimulation of carnitine acylcarnitine translocase activity in heart mitochondria from hyperthyroid rats.
    FEBS letters, 1996, Nov-18, Volume: 397, Issue:2-3

    Topics: Animals; Cardiolipins; Carnitine; Carnitine Acyltransferases; Fatty Acids; Hyperthyroidism; Male; Mi

1996
[Juvenile hyperthyroidism].
    Deutsche medizinische Wochenschrift (1946), 1977, Jan-21, Volume: 102, Issue:3

    Topics: Age Factors; Carnitine; Humans; Hyperthyroidism

1977
Urinary excretion of carnitine in patients with hyperthyroidism and hypothyroidism: augmentation by thyroid hormone.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Carnitine; Fatty Acids, Nonesterified; Female; Humans; Hyperthyroidism; Hypothyro

1977
Mechanisms regulating cardiac fuel selection in hyperthyroidism.
    The Biochemical journal, 1992, Sep-01, Volume: 286 ( Pt 2)

    Topics: Animals; Blotting, Northern; Blotting, Western; Carnitine; Energy Metabolism; Fatty Acids, Nonesteri

1992
[Serum carnitine values in dysthyroidism].
    Presse medicale (Paris, France : 1983), 1992, Jan-18, Volume: 21, Issue:2

    Topics: Carnitine; Humans; Hyperthyroidism; Hypothyroidism; Reference Values

1992
Sarcoplasmic reticulum Ca2+ transport and long chain acylcarnitines in hyperthyroidism.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:2

    Topics: Animals; Biological Transport; Body Weight; Calcium; Carnitine; Heart; Hyperthyroidism; Lipid Metabo

1988
The relationship between fat synthesis and oxidation in the liver after re-feeding and its regulation by thyroid hormone.
    The Biochemical journal, 1987, Nov-01, Volume: 247, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Fatty Acids, Nonesterified;

1987
[New methods for the diagnosis and therapy of hyperthyroidism].
    Munchener medizinische Wochenschrift (1950), 1967, Oct-27, Volume: 109, Issue:43

    Topics: Adolescent; Adult; Age Factors; Animals; Basal Metabolism; Carnitine; Female; Humans; Hydroxyproline

1967
Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle: comparative aspects.
    European journal of clinical investigation, 1972, Volume: 2, Issue:3

    Topics: Acyltransferases; Alcohol Oxidoreductases; Animals; Biopsy; Carnitine; Enzymes; Fructose-Bisphosphat

1972
[Proceedings: Changes in the quantity of carnitine excreted in the urine in hyperthyroidism and hypothyroidism].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Carnitine; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged

1974
[Use of carnitine in connective tissue diseases].
    Dermatologische Monatschrift, 1971, Volume: 157, Issue:7

    Topics: Adult; Carnitine; Collagen Diseases; Female; Humans; Hyperthyroidism; Male; Middle Aged; Scleroderma

1971
[Clinical application of carnitine in hyperthyroidism].
    Das Deutsche Gesundheitswesen, 1967, Oct-26, Volume: 22, Issue:43

    Topics: Animals; Antithyroid Agents; Carnitine; Humans; Hyperthyroidism; Iodine Radioisotopes; Rats; Thyroxi

1967
[Effect of carnitine of the accumulation of iodine in the thyroid gland].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1965, Volume: 25, Issue:3

    Topics: Animals; Carnitine; Hyperthyroidism; Iodine; Iodine Isotopes; Iodine Radioisotopes; Rats; Thyroid Gl

1965