Page last updated: 2024-10-16

carnitine and Hyperlipidemias

carnitine has been researched along with Hyperlipidemias in 46 studies

Hyperlipidemias: Conditions with excess LIPIDS in the blood.

Research Excerpts

ExcerptRelevanceReference
"To develop a therapeutic agent for obesity-related metabolic disorders, a mixture of dietary components was prepared, including grape extract, green tea extract and l-carnitine (RGTC), and its effects on obesity, hyperlipidemia and non-alcoholic fatty liver disease examined."7.77A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, K; Lee, KH; Lee, WK; Ly, SY; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011)
"Overweight patients with hyperlipidemia (serum triglyceride ≥ 1."6.80Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. ( Du, S; Jiang, S; Li, Y; Na, L; Niu, Y; Sun, C; Zhang, Q; Zhang, W, 2015)
"This study was designed to investigate the effect of hypercholesterolemia on the reproductive performance of premature male rats and to evaluate the influence of L-Carnitine (CAR) in maintaining their fertility."5.51L-Carnitine effect on induced hyperlipidemia on premature rats: fertility profile. ( Al-Delemi, DHJ; Al-Nailey, KGC; Alebady, AS; Karam, KM, 2022)
" Serum markers of endothelial dysfunction and inflammation were unchanged, but short-chain acylcarnitine concentrations were significantly decreased."3.79Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease. ( Baldwin, A; Blewett, H; Guzman, RP; O, K; Taylor, CG; Weighell, W; Wright, B; Zahradka, P, 2013)
"To develop a therapeutic agent for obesity-related metabolic disorders, a mixture of dietary components was prepared, including grape extract, green tea extract and l-carnitine (RGTC), and its effects on obesity, hyperlipidemia and non-alcoholic fatty liver disease examined."3.77A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, K; Lee, KH; Lee, WK; Ly, SY; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011)
"Hyperlipidemia is a key risk factor for cardiovascular disease, and it is associated with lipid metabolic disorders and gut microbiota dysbiosis."3.30Probio-X Relieves Symptoms of Hyperlipidemia by Regulating Patients' Gut Microbiome, Blood Lipid Metabolism, and Lifestyle Habits. ( A, L; Guo, R; Han, H; Li, Y; Ma, C; Shang, D; Sun, Z; Wang, H; Yang, C; Yang, F; Zhang, H; Zhang, L; Zhang, Y; Zhao, F, 2023)
"Overweight patients with hyperlipidemia (serum triglyceride ≥ 1."2.80Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. ( Du, S; Jiang, S; Li, Y; Na, L; Niu, Y; Sun, C; Zhang, Q; Zhang, W, 2015)
"Hyperlipidemia and obesity are associated with metabolic syndrome and increased risk in developing diabetes and cardiovascular disease."2.76A combination of (ω-3) polyunsaturated fatty acids, polyphenols and L-carnitine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation in human peripheral blood mononuclear cells and HepG2 cells. ( Anderwald, C; Anzur, C; Brachinger, M; Eller-Berndl, D; Fischer, A; Krepp, R; Laschan, C; Lechner, S; Lienbacher, G; Lohninger, A; Mascher, D; Radler, U; Schoerg, G; Stangl, H; Zeller, E, 2011)
"L-carnitine was randomly administered to 81 patients at an oral dose of g 4/die for 12 months, in addition to the pharmacological treatment generally used."2.67Controlled study on L-carnitine therapeutic efficacy in post-infarction. ( Bigalli, A; Boem, A; Davini, P; Lamanna, F, 1992)
"Carnitine is a selective carrier of free fatty acids from the cytoplasm to the mitochondria."2.65L-carnitine in haemodialysed patients. Changes in lipid pattern. ( Caruso, U; Casciani, CU; Corsi, M; Cravotto, E; D'Iddio, S; Grilli, M; Pola, P; Savi, L, 1982)
"Hyperlipidemia is a risk factor for initiation and progression of diabetic nephropathy but the metabolic pathways altered in the diabetic kidney in a context of hyperlipidemia remain incompletely described."1.46Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia. ( Bascands, JL; Denis, C; Gillet, M; Klavins, K; Klein, J; Koal, T; Marsal, D; Mirzoyan, K; Saulnier-Blache, JS; Schanstra, JP, 2017)
"Refeeding syndrome has been observed in patients receiving nutrition after a prolonged period of malnourishment and is characterized by multiple metabolic derangements."1.38Fatty emaciation: a case report of suspected fat overload syndrome in oral refeeding. ( Macher, AD; Maviglia, SM; Palazuelos, D, 2012)
"Severe hyperlipidemia was reversed by changing the carnitine deficient diet (Ensureliquid) to a carnitine-containing diet."1.32A case of severe hyperlipidemia caused by long-term tube feedings. ( Hsieh, ST; Ishikawa, Y; Kim, JI; Miki, T; Tanaka, S; Taniguchi, T; Yasumoto, T; Yokoyama, M, 2003)
"Iron deficiency anemia and hyperlipidemia are common public health problems in Turkey."1.31Serum free carnitine and total triglycerid levels in children with iron deficiency anemia. ( Cetinkaya, O; Hizel, S; Sekreter, E; Tanzer, F, 2001)
"L-carnitine treatment had no effect on the FCRs of VLDL-TG and VLDL-apoB or on the transport of VLDL-apoB."1.29Effect of L-carnitine treatment on very low density lipoprotein kinetics in the hyperlipidemic rabbit. ( Bhuiyan, AK; Foster, D; James, L; Seccombe, D, 1995)
" At the end of the experimental protocol, L-carnitine dosage was increased to 60 mg/kg iv (at the end of each dialysis) in four patients of the group of nonresponders and prolonged for 60 days."1.27Favorable effects of L-carnitine treatment on hypertriglyceridemia in hemodialysis patients: decisive role of low levels of high-density lipoprotein-cholesterol. ( Corsi, M; Giorcelli, G; Siliprandi, N; Vacha, GM, 1983)
"Carnitine pretreatment stimulated ketogenesis."1.27L-carnitine effect on plasma lipoproteins of hyperlipidemic fat-loaded rats. ( Angelucci, L; Arseni, A; Chiodi, P; Hulsmann, WC; Maccari, F; Ramacci, MT, 1987)
"3."1.27The influence of diet and carnitine supplementation on plasma carnitine, cholesterol and triglyceride in WHHL (Watanabe-heritable hyperlipidemic), Netherland dwarf and New Zealand rabbits (Oryctolagus cuniculus). ( Bell, FP; Patnode, CL; Raymond, TL, 1987)
"L-carnitine was found to reduce the level of myocardial long-chain acylcarnitine which was increased by the olive oil treatment."1.27The effect of exogenous L-carnitine on biochemical parameters in serum and in heart of the hyperlipidaemic rat. ( Angelucci, L; Arseni, A; Chiodi, P; Maccari, F; Ramacci, MT, 1987)
"L-Carnitine treatment blunted the magnitude of the diet induced increase in 7 alpha-hydroxylase activity, yet overall the activity still remained elevated relative to controls."1.27L-carnitine treatment in the hyperlipidemic rabbit. ( Hahn, P; James, L; Jones, E; Seccombe, DW, 1987)
"Oral carnitine has been reported to have a lipid-lowering effect with concomitant elevation of high density lipoprotein cholesterol (HDL-C) levels in normo- and hyperlipidemic individuals."1.27Plasma carnitine and lipid-lowering drugs. ( Davignon, J; Nestruck, AC; Pande, SV, 1985)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199023 (50.00)18.7374
1990's6 (13.04)18.2507
2000's5 (10.87)29.6817
2010's10 (21.74)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Karam, KM1
Alebady, AS1
Al-Nailey, KGC1
Al-Delemi, DHJ1
Wang, H1
Ma, C1
Li, Y2
Zhang, L1
A, L1
Yang, C1
Zhao, F1
Han, H1
Shang, D1
Yang, F1
Zhang, Y1
Zhang, H1
Sun, Z1
Guo, R1
Nie, Q1
Xing, M1
Chen, H1
Hu, J1
Nie, S1
Mirzoyan, K1
Klavins, K1
Koal, T1
Gillet, M1
Marsal, D1
Denis, C1
Klein, J1
Bascands, JL1
Schanstra, JP1
Saulnier-Blache, JS1
Zahradka, P1
Wright, B1
Weighell, W1
Blewett, H1
Baldwin, A1
O, K1
Guzman, RP1
Taylor, CG1
Fiamoncini, J1
Lima, TM1
Hirabara, SM1
Ecker, J1
Gorjão, R1
Romanatto, T1
ELolimy, A1
Worsch, S1
Laumen, H1
Bader, B1
Daniel, H1
Curi, R1
Na, L1
Zhang, Q1
Jiang, S1
Du, S1
Zhang, W1
Sun, C1
Niu, Y1
Allam-Ndoul, B1
Guénard, F1
Garneau, V1
Cormier, H1
Barbier, O1
Pérusse, L1
Vohl, MC1
Kang, JS1
Lee, WK1
Yoon, WK1
Kim, N1
Park, SK2
Park, HK1
Ly, SY1
Han, SB1
Yun, J1
Lee, CW1
Lee, K1
Lee, KH1
Kim, HM1
Radler, U1
Stangl, H1
Lechner, S1
Lienbacher, G1
Krepp, R1
Zeller, E1
Brachinger, M1
Eller-Berndl, D1
Fischer, A1
Anzur, C1
Schoerg, G1
Mascher, D1
Laschan, C1
Anderwald, C1
Lohninger, A1
Macher, AD1
Palazuelos, D1
Maviglia, SM1
Wanner, C2
Wieland, H1
Nauck, M1
Schaeffer, G1
Schollmeyer, P1
Hörl, WH2
Reimann, M1
Peitzsch, M1
Ziemssen, T1
Julius, U1
Eisenhofer, G1
Merkel, M1
Greten, H1
BEKAERT, J1
DELTOUR, G1
Tanaka, S1
Miki, T1
Hsieh, ST1
Kim, JI1
Yasumoto, T1
Taniguchi, T1
Ishikawa, Y1
Yokoyama, M1
Güneş, B1
Yalçin, SS1
Kalkanoğlu, HS1
Onol, S1
Dursun, A1
Coşkun, T1
Vacha, GM1
Giorcelli, G1
Siliprandi, N1
Corsi, M2
Maebashi, M2
Imamura, A2
Yoshinaga, K2
Sato, T1
Funyu, T1
Ishidoya, Y1
Hirayama, N1
Albertazzi, A1
Capelli, P1
Di Paolo, B1
Pola, P2
Tondi, P1
Vaccario, O1
Casciani, CU1
Caruso, U1
Cravotto, E1
D'Iddio, S1
Savi, L1
Grilli, M1
Bertoli, M1
Battistella, PA1
Vergani, L1
Naso, A1
Gasparotto, ML1
Romagnoli, GF1
Angelini, C1
Spagnoli, LG1
Orlandi, A1
Marino, B1
Mauriello, A1
De Angelis, C1
Ramacci, MT5
James, L2
Bhuiyan, AK1
Foster, D1
Seccombe, D1
Sirtori, CR1
Calabresi, L1
Ferrara, S1
Pazzucconi, F1
Bondioli, A1
Baldassarre, D1
Birreci, A1
Koverech, A1
Tanzer, F1
Hizel, S1
Cetinkaya, O1
Sekreter, E1
Kawamura, N1
Sato, M1
Bougneres, PF1
Lacour, B1
di Giulio, S1
Assan, R1
Davini, P1
Bigalli, A1
Lamanna, F1
Boem, A1
Dhalla, NS1
Elimban, V1
Rupp, H1
Mimura, K1
Yukawa, S1
Raymond, TL2
Reynolds, SA1
Swanson, JA1
Patnode, CA1
Bell, FP2
Maccari, F4
Arseni, A3
Chiodi, P3
Angelucci, L4
Hulsmann, WC1
Rebouche, CJ1
Paulson, DJ1
Kendler, BS1
Patnode, CL1
Wakabayashi, Y1
Okubo, M1
Shimada, H1
Sato, N1
Koide, A1
Marumo, F1
Nakamura, H1
Seccombe, DW1
Hahn, P1
Jones, E1
Novoa, D1
Rodriguez-Segade, S1
Romero, R1
Arcocha, V1
Alonso de la Peña, C1
Paz, M1
del Río, A1
del Río, R1
Borum, PR1
Taggart, EM1
Pessotto, P1
Nestruck, AC1
Pande, SV1
Davignon, J1
Szamosi, T1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Blinded, Randomized, Controlled Study to Examine the Bioavailability of Compounds From Different Bean Varieties in Healthy Individuals.[NCT02342340]8 participants (Actual)Interventional2015-01-31Completed
Correlation Between Carnitine Deficiency and Hypoglycemic Events in Type I Diabetes; Effects of Carnitine Supplementation on Hypoglycemic Events in Type I Diabetes[NCT00351234]200 participants (Actual)Observational2004-10-31Completed
In Vivo Study of Safety, Tolerability and Dosing Effect on SMN mRNA and Protein Levels of Valproic Acid in Patients With Spinal Muscular Atrophy[NCT00374075]Phase 142 participants Interventional2003-09-30Completed
Phase I/II Trial of Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy Type I (CARNI-VAL Type I)[NCT00661453]Phase 1/Phase 240 participants (Actual)Interventional2008-04-30Completed
Multi-center Phase II Trial of Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy (SMA CARNI-VAL Trial)[NCT00227266]Phase 294 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Anthropometric Measures of Nutritional Status (Body Mass Index [BMI] Z-scores, Weight for Length Ratios, Lean/Fat Mass Via DEXA, Growth Parameters, and Triceps Skinfold Measures)

(NCT00661453)
Timeframe: -2 weeks, time 0, 3 months, 6 months

Interventiong (Mean)
Lean Mass BaselineLean Mass 3 monthsLean Mass 6 monthsFat Mass BaselineFat Mass 3 monthsFat Mass 6 months
SMA Type 14317.154993.925133.833011.373618.254316.08

Max CMAP Amplitude (Mean)

The maximum Compound Motor Action Potential (CMAP) is a measurement obtained through EMG testing that is associated with disease progression. In this study, we measure the maximum CMAP by stimulating one nerve in the hand and measuring the response of the muscle. This is done multiple times, the outcome used is the highest peak, or response observed. (NCT00227266)
Timeframe: 1 month prior to official enrollment, beginning of study (0 months), 6 months, 12 months (data point not available)

,,
InterventionmV (Mean)
Baseline6 months
Cohort 1a Sitters Placebo Then Treatment2.282.32
Cohort 1b Sitters Treatment2.932.37
Cohort 2 Standers and Walkers - Treatment5.526.56

Max CMAP Amplitude Median

The maximum Compound Motor Action Potential (CMAP) is a measurement obtained through EMG testing that is associated with disease progression. In this study, we measure the maximum CMAP by stimulating one nerve in the hand and measuring the response of the muscle. This is done multiple times, the outcome used is the highest peak, or response observed. (NCT00227266)
Timeframe: 1 month prior to official enrollment, beginning of study (0 months), 6 months, 12 months (data point not available)

,,
InterventionmV (Median)
Baseline6 months
Cohort 1a Sitters Placebo Then Treatment1.911.44
Cohort 1b Sitters Treatment2.21.8
Cohort 2 Standers and Walkers - Treatment5.35.85

Max CMAP Area (Mean)

The maximum Compound Motor Action Potential (CMAP) area is a measurement obtained through EMG testing that is associated with disease progression. In this study, we measure the maximum CMAP by stimulating one nerve in the hand and measuring the response of the muscle. This procedure is repeated multiple times. The maximum area is the response that results in the largest area under the response curve. (NCT00227266)
Timeframe: 1 month prior to official enrollment, beginning of study (0 months), 6 months, 12 months (data point not available)

,,
InterventionmVms (Mean)
Baseline6 months
Cohort 1a Sitters Placebo Then Treatment5.465.28
Cohort 1b Sitters Treatment5.455.26
Cohort 2 Standers and Walkers - Treatment14.8516.26

Max CMAP Area (Median)

The maximum Compound Motor Action Potential (CMAP) area is a measurement obtained through EMG testing that is associated with disease progression. In this study, we measure the maximum CMAP by stimulating one nerve in the hand and measuring the response of the muscle. This procedure is repeated multiple times. The maximum area is the response that results in the largest area under the response curve. (NCT00227266)
Timeframe: 1 month prior to official enrollment, beginning of study (0 months), 6 months, 12 months (data point not available)

,,
InterventionmVms (Median)
Baseline6 months
Cohort 1a Sitters Placebo Then Treatment3.63.74
Cohort 1b Sitters Treatment4.63.4
Cohort 2 Standers and Walkers - Treatment13.6516.85

Modified Hammersmith Change From Baseline to 6 Months

Comparison of Modified Hammersmith Change from baseline to 6 months. Scores range from 0 to 40. A higher score indicates a better outcome. This scale is used to assess gross motor abilities of non-ambulant children with SMA in multiple research trials as well as in clinical settings. (NCT00227266)
Timeframe: 0 months, 6 months

,
InterventionScore (Mean)
Baseline visit (0 weeks)6 Month visit (V2)Change from Baseline
Cohort 1a Sitters Placebo Then Treatment20.020.60.6
Cohort 1b Sitters Treatment16.616.80.2

Modified Hammersmith Extend Baseline

"Baseline Modified Hammersmith Extend testing. The baseline test is the score they receive during their screening visits. This scale ranges from 0 to 56. A higher score indicates a better outcome.~This scale is used to assess gross motor abilities of children with SMA in multiple research trials as well as in clinical settings." (NCT00227266)
Timeframe: 1 month prior to enrollment, at enrollment (0 months)

InterventionScore (Mean)
Modified Hammersmith Extend at S1 (-4 weeks)Modified Hammersmith Extend at S2 (0 weeks)
Cohort 2 Experimental47.048.3

Reviews

3 reviews available for carnitine and Hyperlipidemias

ArticleYear
Paradoxical role of lipid metabolism in heart function and dysfunction.
    Molecular and cellular biochemistry, 1992, Oct-21, Volume: 116, Issue:1-2

    Topics: Adenosine Triphosphatases; Animals; Carnitine; Diabetes Complications; Diabetes Mellitus; Diabetes M

1992
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine metabolism and function in humans.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Absorption; Acidosis; Adolescent; Adult; Aged; Animals; Biological Transport; Cardiomyopathies; Carn

1986
Carnitine: an overview of its role in preventive medicine.
    Preventive medicine, 1986, Volume: 15, Issue:4

    Topics: Animals; Cardiovascular Diseases; Carnitine; Humans; Hyperlipidemias; Infant, Newborn

1986

Trials

9 trials available for carnitine and Hyperlipidemias

ArticleYear
L-Carnitine effect on induced hyperlipidemia on premature rats: fertility profile.
    Journal of medicine and life, 2022, Volume: 15, Issue:1

    Topics: Animals; Carnitine; Fertility; Follicle Stimulating Hormone; Hypercholesterolemia; Hyperlipidemias;

2022
Probio-X Relieves Symptoms of Hyperlipidemia by Regulating Patients' Gut Microbiome, Blood Lipid Metabolism, and Lifestyle Habits.
    Microbiology spectrum, 2023, 06-15, Volume: 11, Issue:3

    Topics: Bifidobacterium animalis; Carnitine; Cholesterol; Gastrointestinal Microbiome; Humans; Hyperlipidemi

2023
Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial.
    Scientific reports, 2015, May-19, Volume: 5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Blood Glucose; Carnitine; Cholesterol, HDL; Dietary Supplement

2015
A combination of (ω-3) polyunsaturated fatty acids, polyphenols and L-carnitine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation in human peripheral blood mononuclear cells and HepG2 cells.
    Annals of nutrition & metabolism, 2011, Volume: 58, Issue:2

    Topics: Adult; Carnitine; Double-Blind Method; Fatty Acids; Fatty Acids, Omega-3; Female; Flavonoids; Functi

2011
Effective hypolipidaemic therapy with beclobrate in haemodialysis patients: interference with L-carnitine.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1990, Volume: 5, Issue:8

    Topics: Benzhydryl Compounds; Carnitine; Cholesterol; Female; Humans; Hyperlipidemias; Hypolipidemic Agents;

1990
L-carnitine in haemodialysed patients. Changes in lipid pattern.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:3

    Topics: Adult; Carnitine; Female; Humans; Hyperlipidemias; Lipids; Male; Renal Dialysis

1982
L-carnitine reduces plasma lipoprotein(a) levels in patients with hyper Lp(a).
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2000, Volume: 10, Issue:5

    Topics: Aged; Cardiovascular Diseases; Carnitine; Double-Blind Method; Female; Humans; Hyperlipidemias; Hypo

2000
Lipid-lowering effect of carnitine in patients with type-IV hyperlipoproteinaemia.
    Lancet (London, England), 1978, Oct-14, Volume: 2, Issue:8094

    Topics: Administration, Oral; Adult; Blood Glucose; Carnitine; Cholesterol; Fatty Acids, Nonesterified; Huma

1978
Controlled study on L-carnitine therapeutic efficacy in post-infarction.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Carnitine; Fe

1992

Other Studies

34 other studies available for carnitine and Hyperlipidemias

ArticleYear
Metabolomics and Lipidomics Profiling Reveals Hypocholesterolemic and Hypolipidemic Effects of Arabinoxylan on Type 2 Diabetic Rats.
    Journal of agricultural and food chemistry, 2019, Sep-25, Volume: 67, Issue:38

    Topics: Amino Acids, Branched-Chain; Animals; Anticholesteremic Agents; Bile Acids and Salts; Carnitine; Dia

2019
Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia.
    Biochemical and biophysical research communications, 2017, 05-20, Volume: 487, Issue:1

    Topics: Animals; Apolipoproteins E; Biomarkers; Carnitine; Diabetic Nephropathies; Hyperlipidemias; Male; Mi

2017
Daily non-soy legume consumption reverses vascular impairment due to peripheral artery disease.
    Atherosclerosis, 2013, Volume: 230, Issue:2

    Topics: Aged; Aged, 80 and over; Ankle Brachial Index; Atherosclerosis; Biomarkers; Carnitine; Carotid Steno

2013
Medium-chain dicarboxylic acylcarnitines as markers of n-3 PUFA-induced peroxisomal oxidation of fatty acids.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:8

    Topics: Animals; Biomarkers; Carnitine; Diet, High-Fat; Dietary Fats; Dietary Fats, Unsaturated; Fatty Acids

2015
Association between Metabolite Profiles, Metabolic Syndrome and Obesity Status.
    Nutrients, 2016, May-27, Volume: 8, Issue:6

    Topics: Adult; Amino Acids; Body Mass Index; Cardiovascular Diseases; Carnitine; Cholesterol; Cholesterol, H

2016
A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:12

    Topics: Adipose Tissue; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carnitine;

2011
Fatty emaciation: a case report of suspected fat overload syndrome in oral refeeding.
    JPEN. Journal of parenteral and enteral nutrition, 2012, Volume: 36, Issue:4

    Topics: Administration, Oral; Anorexia Nervosa; Carnitine; Dietary Fats; Female; Humans; Hyperlipidemias; Ma

2012
Metabolomic distinction of microvascular effects of lipoprotein apheresis--a pilot study.
    Atherosclerosis. Supplements, 2013, Volume: 14, Issue:1

    Topics: Adult; Aged; Biomarkers; Blood Component Removal; Carnitine; Chi-Square Distribution; Decision Trees

2013
[L-carnitine and lipid lowering].
    Deutsche medizinische Wochenschrift (1946), 2003, Aug-22, Volume: 128, Issue:34-35

    Topics: Adipose Tissue; Carnitine; Energy Metabolism; Humans; Hyperlipidemias; Lipid Metabolism; Lipids; Mus

2003
[Effect of carnitine on diabetic hyperlipemia].
    Clinica chimica acta; international journal of clinical chemistry, 1960, Volume: 5

    Topics: Carnitine; Diabetes Complications; Diabetes Mellitus; Folic Acid; Humans; Hyperlipidemias; Lipids; V

1960
A case of severe hyperlipidemia caused by long-term tube feedings.
    Journal of atherosclerosis and thrombosis, 2003, Volume: 10, Issue:5

    Topics: Aged; Carnitine; Dietary Sucrose; Enteral Nutrition; Female; Food, Formulated; Humans; Hyperlipidemi

2003
The effect of oral L-carnitine supplementation on the lipid profiles of hyperlipidaemic children.
    Acta paediatrica (Oslo, Norway : 1992), 2005, Volume: 94, Issue:6

    Topics: Administration, Oral; Carnitine; Child; Cholesterol; Dietary Supplements; Female; Humans; Hyperlipid

2005
Favorable effects of L-carnitine treatment on hypertriglyceridemia in hemodialysis patients: decisive role of low levels of high-density lipoprotein-cholesterol.
    The American journal of clinical nutrition, 1983, Volume: 38, Issue:4

    Topics: Adult; Apolipoproteins; Apolipoproteins A; Carnitine; Cholesterol; Cholesterol, HDL; Female; Humans;

1983
Carnitine depletion as a probable cause of hyperlipidemia in uremic patients on maintenance hemodialysis.
    The Tohoku journal of experimental medicine, 1983, Volume: 139, Issue:1

    Topics: Adult; Amino Acids; Carnitine; Humans; Hyperlipidemias; Kinetics; Middle Aged; Renal Dialysis; Trigl

1983
Endocrine-metabolic effects of l-carnitine in patients on regular dialysis treatment.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1983, Volume: 19

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Carnitine; Cholesterol; Cholesterol, HDL; Female; Hormones

1983
Carnitine deficiency induced during hemodialysis and hyperlipidemia: effect of replacement therapy.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:8

    Topics: Adult; Carnitine; Female; Humans; Hyperlipidemias; Lipid Metabolism; Male; Middle Aged; Muscles; Ren

1981
Propionyl-L-carnitine prevents the progression of atherosclerotic lesions in aged hyperlipemic rabbits.
    Atherosclerosis, 1995, Apr-07, Volume: 114, Issue:1

    Topics: Aging; Animals; Arteriosclerosis; Carnitine; Cell Division; Diet; Disease Models, Animal; Female; Fo

1995
Effect of L-carnitine treatment on very low density lipoprotein kinetics in the hyperlipidemic rabbit.
    Clinical biochemistry, 1995, Volume: 28, Issue:4

    Topics: Animals; Apolipoproteins B; Carnitine; Dietary Fats; Glycerol; Hyperlipidemias; Lipoproteins, VLDL;

1995
Serum free carnitine and total triglycerid levels in children with iron deficiency anemia.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2001, Volume: 71, Issue:1

    Topics: Anemia, Iron-Deficiency; Cardiovascular Diseases; Carnitine; Case-Control Studies; Cholesterol; Fema

2001
Hypolipaemic effect of carnitine in uraemic patients.
    Lancet (London, England), 1979, Jun-30, Volume: 1, Issue:8131

    Topics: Carnitine; Humans; Hyperlipidemias; Triglycerides; Uremia

1979
[Hyperlipidemia and drug treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidn

1991
The effect of oral l-carnitine on lipoprotein composition in the Watanabe Heritable Hyperlipidemic Rabbit (Oryctolagus cuniculus).
    Comparative biochemistry and physiology. A, Comparative physiology, 1987, Volume: 88, Issue:3

    Topics: Animals; Carnitine; Cholesterol; Hyperlipidemias; Lipoproteins; Rabbits; Triglycerides

1987
Potential role of carnitine in patients with renal insufficiency.
    Klinische Wochenschrift, 1986, Jul-01, Volume: 64, Issue:13

    Topics: Acetylcarnitine; Carnitine; Carnitine O-Palmitoyltransferase; Creatinine; Humans; Hyperlipidemias; K

1986
L-carnitine effect on plasma lipoproteins of hyperlipidemic fat-loaded rats.
    Lipids, 1987, Volume: 22, Issue:12

    Topics: Animals; Carnitine; Chylomicrons; Dietary Fats, Unsaturated; Fatty Acids, Nonesterified; Female; Hyp

1987
[Effect of L-carnitine on various biochemical parameters of the heart, liver and serum of the hyperlipemic rat].
    Cardiologia (Rome, Italy), 1986, Volume: 31, Issue:7

    Topics: Animals; Carnitine; Hyperlipidemias; Lipid Metabolism; Liver; Male; Myocardium; Random Allocation; R

1986
The influence of diet and carnitine supplementation on plasma carnitine, cholesterol and triglyceride in WHHL (Watanabe-heritable hyperlipidemic), Netherland dwarf and New Zealand rabbits (Oryctolagus cuniculus).
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1987, Volume: 87, Issue:3

    Topics: Animals; Carnitine; Cholesterol; Diet; Female; Hyperlipidemias; Male; Rabbits; Triglycerides

1987
Decreased VLDL apoprotein CII/apoprotein CIII ratio may be seen in both normotriglyceridemic and hypertriglyceridemic patients on chronic hemodialysis treatment.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:9

    Topics: Adult; Apolipoprotein C-II; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins C; Carnitine; Fem

1987
The effect of exogenous L-carnitine on biochemical parameters in serum and in heart of the hyperlipidaemic rat.
    Basic research in cardiology, 1987, Volume: 82 Suppl 1

    Topics: Animals; Carnitine; Dietary Fats, Unsaturated; Hyperlipidemias; Male; Myocardium; Olive Oil; Plant O

1987
L-carnitine treatment in the hyperlipidemic rabbit.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:12

    Topics: Animals; Body Weight; Carnitine; Dietary Fats; Fatty Liver; Hyperlipidemias; Hypolipidemic Agents; L

1987
Carnitine levels and hypertriglyceridemia in undialyzed patients.
    Nephron, 1987, Volume: 47, Issue:3

    Topics: Carnitine; Female; Humans; Hyperlipidemias; Kidney Failure, Chronic; Male; Renal Dialysis; Triglycer

1987
Carnitine nutriture of dialysis patients.
    Journal of the American Dietetic Association, 1986, Volume: 86, Issue:5

    Topics: Arrhythmias, Cardiac; Carnitine; Humans; Hyperlipidemias; Muscular Diseases; Nutritional Requirement

1986
The effect of exogenous L-carnitine on fat diet-induced hyperlipidemia in the rat.
    Life sciences, 1985, May-20, Volume: 36, Issue:20

    Topics: Acetylcarnitine; Acylation; Animals; Carnitine; Dietary Fats; Fatty Acids, Nonesterified; Feces; Hyp

1985
Plasma carnitine and lipid-lowering drugs.
    Atherosclerosis, 1985, Volume: 55, Issue:3

    Topics: Carnitine; Cholesterol, HDL; Clofibrate; Female; Humans; Hyperlipidemia, Familial Combined; Hyperlip

1985
Alterations of fatty acid metabolism in liver cells of hyperlipaemic old rats.
    Experimental gerontology, 1972, Volume: 7, Issue:2

    Topics: Acetates; Aging; Animals; Carbon Isotopes; Carnitine; Coenzyme A; Cytoplasm; Fatty Acids; Fatty Acid

1972