Page last updated: 2024-10-16

carnitine and Hypercholesterolemia

carnitine has been researched along with Hypercholesterolemia in 11 studies

Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to investigate the effect of hypercholesterolemia on the reproductive performance of premature male rats and to evaluate the influence of L-Carnitine (CAR) in maintaining their fertility."5.51L-Carnitine effect on induced hyperlipidemia on premature rats: fertility profile. ( Al-Delemi, DHJ; Al-Nailey, KGC; Alebady, AS; Karam, KM, 2022)
"A previous study has demonstrated that L-carnitine reduces plasma lipoprotein(a) (Lp[a]) levels in patients with hypercholesterolemia."5.10The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus. ( Ciccarelli, L; Cicero, AF; Derosa, G; Fogari, R; Gaddi, A; Mugellini, A, 2003)
"Patients with type 2 diabetes are under high oxidative stress, and levels of hyperglycemia correlate strongly with levels of LDL oxidation."2.74L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes. ( Avitabile, T; Cammalleri, L; Malaguarnera, M; Motta, M; Vacante, M, 2009)
"Pretreatment with coenzyme Q10 (10 mg/kg/day, oral) and L-Carnitine (350 mg/kg/day, oral) were conducted for 5 consecutive weeks."1.40CoQ10 and L-carnitine attenuate the effect of high LDL and oxidized LDL on spermatogenesis in male rats. ( Garjani, A; Ghanbarzadeh, S; Khorrami, A; Ziaee, M, 2014)
"Body weight gain was significantly higher in the H-SC group than in the H-SV group."1.36Stevia rebaudiana Bertoni extract supplementation improves lipid and carnitine profiles in C57BL/6J mice fed a high-fat diet. ( Cha, YS; Park, JE, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Karam, KM1
Alebady, AS1
Al-Nailey, KGC1
Al-Delemi, DHJ1
Nie, Q1
Xing, M1
Chen, H1
Hu, J1
Nie, S1
Ghanbarzadeh, S1
Garjani, A1
Ziaee, M1
Khorrami, A1
Malaguarnera, M2
Vacante, M1
Avitabile, T1
Cammalleri, L1
Motta, M1
Park, JE1
Cha, YS1
Derosa, G1
Cicero, AF1
Gaddi, A1
Mugellini, A1
Ciccarelli, L1
Fogari, R1
Bell, FP2
DeLucia, AJ1
Grizard, G1
Sion, B1
Jouanel, P1
Benoit, P1
Boucher, D1
Sayed-Ahmed, MM1
Khattab, MM1
Gad, MZ1
Mostafa, N1
Gillies, PJ1
Hashimoto, S1
Dayton, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of a Bakery Product Enriched With Fibre and L-carnitine on Cardiovascular Risk Parameters in Patients With Metabolic Syndrome: a Randomized, Double-blind, Placebo-controlled Study[NCT02281253]54 participants (Actual)Interventional2010-04-30Completed
Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940]Phase 3120 participants (Actual)Interventional2018-05-28Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for carnitine and Hypercholesterolemia

ArticleYear
L-Carnitine effect on induced hyperlipidemia on premature rats: fertility profile.
    Journal of medicine and life, 2022, Volume: 15, Issue:1

    Topics: Animals; Carnitine; Fertility; Follicle Stimulating Hormone; Hypercholesterolemia; Hyperlipidemias;

2022
L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:1

    Topics: Apolipoprotein A-I; Apolipoprotein B-100; Blood Glucose; Body Mass Index; Carnitine; Cholesterol; Ch

2009
The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus.
    Clinical therapeutics, 2003, Volume: 25, Issue:5

    Topics: Blood Glucose; Carnitine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hyperchole

2003

Other Studies

8 other studies available for carnitine and Hypercholesterolemia

ArticleYear
Metabolomics and Lipidomics Profiling Reveals Hypocholesterolemic and Hypolipidemic Effects of Arabinoxylan on Type 2 Diabetic Rats.
    Journal of agricultural and food chemistry, 2019, Sep-25, Volume: 67, Issue:38

    Topics: Amino Acids, Branched-Chain; Animals; Anticholesteremic Agents; Bile Acids and Salts; Carnitine; Dia

2019
CoQ10 and L-carnitine attenuate the effect of high LDL and oxidized LDL on spermatogenesis in male rats.
    Drug research, 2014, Volume: 64, Issue:10

    Topics: Animals; Antioxidants; Carnitine; Cell Survival; Cholesterol, Dietary; Cytoprotection; Disease Model

2014
Stevia rebaudiana Bertoni extract supplementation improves lipid and carnitine profiles in C57BL/6J mice fed a high-fat diet.
    Journal of the science of food and agriculture, 2010, Volume: 90, Issue:7

    Topics: Animals; Body Weight; Carnitine; Dietary Fats; Dietary Sucrose; Dietary Supplements; Enzymes; Hyperc

2010
Plasma and liver carnitine (free and esterified) levels and their interrelationships in moderately hypercholesterolemic monkeys (Macaca arctoides).
    Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1983, Volume: 61, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetylcarnitine; Animals; Carnitine; Hydroxybutyrates; Hypercholesterolemia;

1983
Cholesterol, phospholipids and markers of the function of the accessory sex glands in the semen of men with hypercholesterolaemia.
    International journal of andrology, 1995, Volume: 18, Issue:3

    Topics: Acid Phosphatase; Apolipoproteins A; Apolipoproteins B; Biomarkers; Carnitine; Cholesterol; Choleste

1995
L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolaemic rabbits.
    Pharmacological research, 2001, Volume: 44, Issue:3

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Carnitine; Coronary Vessels; Hypercholesterolemia; Male;

2001
Uptake and esterification of circulating carnitine by aorta and heart in rabbits in vivo.
    Atherosclerosis, 1979, Volume: 33, Issue:1

    Topics: Animals; Aorta; Carnitine; Cholesterol, Dietary; Diet, Atherogenic; Esterification; Hypercholesterol

1979
Oxidation of palmityl-CoA to CO2 by normal and atherosclerotic aortic mitochondria.
    Life sciences, 1974, Mar-01, Volume: 14, Issue:5

    Topics: Adenosine Diphosphate; Albumins; Animals; Aorta; Arteriosclerosis; Carbon Dioxide; Carbon Radioisoto

1974