carnitine has been researched along with Heart Disease, Ischemic in 74 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-chain acylcarnitines accumulate during myocardial ischemia and contribute to membrane dysfunction in ischemic zones." | 7.69 | Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool. ( Ford, DA; Gross, RW; Han, X; Horner, CC, 1996) |
| "During myocardial ischemia, inhibition of the carnitine-mediated transportation of fatty acid may be beneficial because it facilitates glucose utilization and prevents an accumulation of fatty acid metabolites." | 7.69 | Inhibition of carnitine synthesis protects against left ventricular dysfunction in rats with myocardial ischemia. ( Aoyagi, T; Eto, Y; Hayashi, Y; Kirimoto, T; Kobayakawa, N; Matsumoto, A; Momomura, S; Omata, M; Sugiura, S; Yokoyama, I; Yonekura, K, 1997) |
| "Carnitine and its derivatives have recently been shown to protect cardiac metabolism and function in ischemic heart disease and other clinical conditions of myocardial ischemia." | 4.81 | Influence of L-carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass. ( Lango, R; Lysiak-Szydlowska, W; Narkiewicz, M; Smolenski, RT; Suchorzewska, J, 2001) |
| "Long-chain acylcarnitines accumulate during myocardial ischemia and contribute to membrane dysfunction in ischemic zones." | 3.69 | Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool. ( Ford, DA; Gross, RW; Han, X; Horner, CC, 1996) |
| "During myocardial ischemia, inhibition of the carnitine-mediated transportation of fatty acid may be beneficial because it facilitates glucose utilization and prevents an accumulation of fatty acid metabolites." | 3.69 | Inhibition of carnitine synthesis protects against left ventricular dysfunction in rats with myocardial ischemia. ( Aoyagi, T; Eto, Y; Hayashi, Y; Kirimoto, T; Kobayakawa, N; Matsumoto, A; Momomura, S; Omata, M; Sugiura, S; Yokoyama, I; Yonekura, K, 1997) |
| "Long-chain acylcarnitines (LCA) have been shown to accumulate during myocardial ischemia and to contribute to malignant derangements characteristic of ischemia." | 3.68 | Reperfusion-induced accumulation of long-chain acylcarnitines in previously ischemic myocardium. ( Adames, VR; Heathers, GP; Higgins, AJ; Su, CM, 1993) |
| "L-carnitine is a necessary nutrient for the transport of fatty acids that are required for generating energy." | 2.84 | Effect of L-Carnitine Supplementation on Reverse Remodeling in Patients with Ischemic Heart Disease Undergoing Coronary Artery Bypass Grafting: A Randomized, Placebo-Controlled Trial. ( Boaventura, G; Colafranceschi, A; Costa, B; D'Ippolito, JA; da Costa, C; da Silva Guimarães, S; da Silva, G; da Silva, L; de Carvalho, M; de Souza Cruz, W; Huguenin, AB; Maciel, G; Scalco, F, 2017) |
| "L-Carnitine treatment in combination with other traditional pharmacological therapy might have an additive effect for the improvement of left ventricular function in ischemic cardiomyopathy." | 2.69 | The effects of L-carnitine treatment on left ventricular function and erythrocyte superoxide dismutase activity in patients with ischemic cardiomyopathy. ( Akçil, E; Dinçer, I; Erol, C; Gürlek, A; Kocatürk, PA; Oral, D; Tutar, E, 2000) |
| "Carnitine treatment has cardiovascular benefits including modulation of myocardial metabolism, reduction in necrotic cell death and infarct size, decrease in the incidence of arrhythmias and preservation of mechanical function." | 2.48 | Value of carnitine therapy in kidney dialysis patients and effects on cardiac function from human and animal studies. ( Bhandari, S; Molyneux, R; Seymour, AM, 2012) |
| "Many patients with ischemic heart disease continue to experience anginal symptoms despite revascularization and treatment with antianginal medications." | 2.43 | Metabolic modulators for chronic cardiac ischemia. ( Arora, R; Parang, P; Singh, B, 2005) |
| "L-carnitine has an important role in the metabolism of fatty acids." | 2.38 | New thoughts of pathophysiology and therapy of ischemic heart disease. ( Pepine, CJ, 1991) |
| "Carnitine is a vital biologic substance facilitating fatty acids transport into mitochondria for ATP production." | 1.36 | Pharmacological preconditioning with L-carnitine: relevance to myocardial hemodynamic function and glycogen and lactate content. ( Garjani, A; Ghorbani-Haghjo, A; Javidnia, A; Mohammadi, S; Najafi, M, 2010) |
| "As L-carnitine plays a pivotal role in the balanced metabolism of fatty acids and carbohydrates, this study was carried out to investigate whether long-term mildronate treatment could influence glucose levels and prevent diabetic complications in an experimental model of type 2 diabetes in Goto-Kakizaki (GK) rats." | 1.35 | Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats. ( Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Skapare, E; Svalbe, B; Vilskersts, R; Zvejniece, L, 2009) |
| "Carnitine deficiency was induced in Sprague-Dawley rats by supplementing the drinking water with sodium pivalate for a period of 2 weeks." | 1.31 | Short-term carnitine deficiency does not alter aerobic rat heart function but depresses reperfusion recovery after ischemia. ( Broderick, TL; Cifuentes, J; Green, D; Paulson, DJ, 2001) |
| "Carnitine kinetics were investigated in 28 normotensive patients with significant left coronary artery disease, during and after incremental atrial pacing." | 1.30 | Acute myocardial ischaemia induces cardiac carnitine release in man. ( Bartels, GL; Remme, WJ; Scholte, HR, 1997) |
| "L-carnitine was administered to the carnitine series at doses of 250 mg/kg/day starting 7 days before the ischemic protocol and continuing during the follow-up period (10 and 15 days)." | 1.30 | [Effects of L-carnitine on the regional function of the stunned myocardium caused by ischemia of short duration]. ( Andrés Conejos, F; Capdevila Carbonell, C; Cosín Aguilar, J; Hernándiz Martínez, A; Pallarés Carratalá, V; Portolés Sanz, M, 1997) |
| "L-Carnitine is a key regulatory compound of glucose and fatty acid metabolism in the myocardium." | 1.30 | [The effect of L-carnitine on ischemic heart disease: experimental results]. ( Lerch, R, 1998) |
| "L-Carnitine has been shown to improve the post-ischemic recovery of myocardial function and metabolic measurements that are reduced in the course of ischemia and reperfusion of the heart." | 1.30 | The dose-dependent effects of L-carnitine in myocardial protection in normothermic ischemia. ( Ersöz, A; Gökgöz, L; Kalaycioğlu, S; Oktar, L; Oz, E; Sinci, V; Soncul, H; Tatlican, O; Türközkan, N; Yener, A, 1998) |
| "Carnitine can cause overall improvement in cardiac performance in patients with CAD as well as in cardiomyopathy." | 1.30 | L-carnitine administration in coronary artery disease and cardiomyopathy. ( Aslam, M; Singh, RB, 1998) |
| "L-Propionylcarnitine-treated animals displayed slightly better postischemic recovery of systolic SS than did control animals; to 39 and 28% (p = 0." | 1.29 | L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs. ( Bartels, GL; Bezstarosti, K; Duncker, DJ; Krams, R; Lamers, JM; McFalls, EO; Sassen, LM; van Meegen, JR; Verdouw, PD, 1993) |
| "L-carnitine treatment stimulated glucose oxidation during reperfusion in control and diabetic rat hearts." | 1.29 | L-carnitine increases glucose metabolism and mechanical function following ischaemia in diabetic rat heart. ( Broderick, TL; Lopaschuk, GD; Quinney, HA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 49 (66.22) | 18.2507 |
| 2000's | 19 (25.68) | 29.6817 |
| 2010's | 5 (6.76) | 24.3611 |
| 2020's | 1 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Sánchez-Quintero, MJ | 1 |
| Delgado, J | 1 |
| Medina-Vera, D | 1 |
| Becerra-Muñoz, VM | 1 |
| Queipo-Ortuño, MI | 1 |
| Estévez, M | 1 |
| Plaza-Andrades, I | 1 |
| Rodríguez-Capitán, J | 1 |
| Sánchez, PL | 1 |
| Crespo-Leiro, MG | 1 |
| Jiménez-Navarro, MF | 1 |
| Pavón-Morón, FJ | 1 |
| da Silva Guimarães, S | 1 |
| de Souza Cruz, W | 1 |
| da Silva, L | 1 |
| Maciel, G | 1 |
| Huguenin, AB | 1 |
| de Carvalho, M | 1 |
| Costa, B | 1 |
| da Silva, G | 1 |
| da Costa, C | 1 |
| D'Ippolito, JA | 1 |
| Colafranceschi, A | 1 |
| Scalco, F | 1 |
| Boaventura, G | 1 |
| Ussher, JR | 1 |
| Lopaschuk, GD | 4 |
| Arduini, A | 2 |
| Liepinsh, E | 1 |
| Vilskersts, R | 1 |
| Zvejniece, L | 1 |
| Svalbe, B | 1 |
| Skapare, E | 1 |
| Kuka, J | 1 |
| Cirule, H | 1 |
| Grinberga, S | 1 |
| Kalvinsh, I | 2 |
| Dambrova, M | 2 |
| Najafi, M | 1 |
| Javidnia, A | 1 |
| Ghorbani-Haghjo, A | 1 |
| Mohammadi, S | 1 |
| Garjani, A | 1 |
| Ceccarelli, SM | 1 |
| Chomienne, O | 1 |
| Gubler, M | 1 |
| Molyneux, R | 1 |
| Seymour, AM | 1 |
| Bhandari, S | 1 |
| Hwang, YC | 1 |
| Bakr, S | 2 |
| Ramasamy, R | 2 |
| Bergmann, SR | 2 |
| Onnis, E | 1 |
| Iliceto, S | 4 |
| Schofield, RS | 1 |
| Hill, JA | 1 |
| Daĭia, D | 1 |
| Liepin'sh, E | 1 |
| Kir'ianova, O | 1 |
| Kalvin'sh, I | 1 |
| Sjakste, N | 1 |
| Kleschyov, AL | 1 |
| Boucher, JL | 1 |
| Baumane, L | 1 |
| Dzintare, M | 1 |
| Meirena, D | 1 |
| Sjakste, J | 1 |
| Sydow, K | 1 |
| Münzel, T | 1 |
| Broderick, TL | 5 |
| Paulson, DJ | 4 |
| Gillis, M | 1 |
| Pauly, DF | 1 |
| Pepine, CJ | 2 |
| Ferrari, R | 1 |
| Merli, E | 1 |
| Cicchitelli, G | 1 |
| Mele, D | 1 |
| Fucili, A | 1 |
| Ceconi, C | 1 |
| Su, X | 1 |
| Han, X | 2 |
| Mancuso, DJ | 1 |
| Abendschein, DR | 1 |
| Gross, RW | 2 |
| Mason, KE | 1 |
| Stofan, DA | 1 |
| Szweda, LI | 1 |
| Parang, P | 1 |
| Singh, B | 1 |
| Arora, R | 1 |
| Duncker, DJ | 2 |
| Sassen, LM | 2 |
| Bartels, GL | 4 |
| van Meegen, JR | 1 |
| McFalls, EO | 2 |
| Krams, R | 2 |
| Bezstarosti, K | 2 |
| Lamers, JM | 2 |
| Verdouw, PD | 2 |
| Heathers, GP | 1 |
| Su, CM | 1 |
| Adames, VR | 1 |
| Higgins, AJ | 1 |
| Corr, PB | 2 |
| Yamada, KA | 2 |
| Madden, MC | 1 |
| Wołkowicz, PE | 1 |
| Pohost, GM | 1 |
| McMillin, JB | 2 |
| Pike, MM | 1 |
| Palazzuoli, V | 2 |
| Mondillo, S | 2 |
| Faglia, S | 2 |
| D'Aprile, N | 2 |
| Camporeale, A | 1 |
| Gennari, C | 1 |
| Allely, MC | 1 |
| Brown, CM | 1 |
| Kenny, BA | 1 |
| Kilpatrick, AT | 1 |
| Martin, A | 1 |
| Spedding, M | 1 |
| Quinney, HA | 2 |
| Ribeiro, C | 1 |
| Gamble, J | 1 |
| Hülsmann, WC | 3 |
| Peschechera, A | 2 |
| Arrigoni-Martelli, E | 3 |
| Yamamoto, M | 1 |
| Lee, JD | 1 |
| Shimizu, H | 1 |
| Kawasaki, N | 1 |
| Hara, A | 1 |
| Ishii, Y | 1 |
| Nakamura, T | 1 |
| Remme, WJ | 3 |
| Pillay, M | 1 |
| Schönfeld, DH | 1 |
| Kruijssen, DA | 2 |
| Di Lisa, F | 1 |
| Menabò, R | 1 |
| Barbato, R | 1 |
| Siliprandi, N | 1 |
| Sundqvist, KE | 1 |
| Vuorinen, KH | 1 |
| Peuhkurinen, KJ | 1 |
| Hassinen, IE | 1 |
| Kobayashi, A | 2 |
| Fujisawa, S | 2 |
| Riva, E | 1 |
| Leopaldi, D | 1 |
| Simkhovich, BZ | 1 |
| Hale, SL | 1 |
| Ovize, M | 1 |
| Przyklenk, K | 1 |
| Kloner, RA | 1 |
| McHowat, J | 1 |
| Yan, GX | 1 |
| Donahue, K | 1 |
| Peirick, J | 1 |
| Kléber, AG | 1 |
| Arita, M | 1 |
| Sato, T | 1 |
| Ishida, H | 1 |
| Nakazawa, H | 1 |
| Barker, CC | 1 |
| Tedesco, MA | 1 |
| Ratti, G | 1 |
| Aquino, D | 1 |
| Iacono, A | 1 |
| Ford, DA | 1 |
| Horner, CC | 1 |
| Mangiacotti, L | 1 |
| Campolo, MA | 1 |
| Agricola, E | 1 |
| Serafini, F | 1 |
| Ferrari, LE | 1 |
| Clarke, B | 1 |
| Wyatt, KM | 1 |
| May, GR | 1 |
| McCormack, JG | 1 |
| Rizzon, P | 3 |
| Marangelli, V | 1 |
| den Hartog, FR | 1 |
| Wielenga, RP | 1 |
| Scholte, HR | 1 |
| Aoyagi, T | 1 |
| Sugiura, S | 1 |
| Eto, Y | 1 |
| Yonekura, K | 1 |
| Matsumoto, A | 1 |
| Yokoyama, I | 1 |
| Kobayakawa, N | 1 |
| Omata, M | 1 |
| Kirimoto, T | 1 |
| Hayashi, Y | 1 |
| Momomura, S | 1 |
| Hernándiz Martínez, A | 1 |
| Pallarés Carratalá, V | 1 |
| Cosín Aguilar, J | 1 |
| Andrés Conejos, F | 1 |
| Capdevila Carbonell, C | 1 |
| Portolés Sanz, M | 1 |
| Atar, D | 1 |
| Spiess, M | 1 |
| Mandinova, A | 1 |
| Cierpka, H | 1 |
| Noll, G | 1 |
| Lüscher, TF | 1 |
| Lerch, R | 1 |
| Tatlican, O | 1 |
| Kalaycioğlu, S | 1 |
| Gökgöz, L | 1 |
| Oktar, L | 1 |
| Oz, E | 1 |
| Soncul, H | 1 |
| Sinci, V | 1 |
| Türközkan, N | 1 |
| Yener, A | 1 |
| Ersöz, A | 1 |
| Keller, VA | 1 |
| Toporoff, B | 1 |
| Raziano, RM | 1 |
| Pigott, JD | 1 |
| Mills, NL | 1 |
| Löster, H | 1 |
| Keller, T | 1 |
| Grommisch, J | 1 |
| Gründer, W | 1 |
| Lopaschuk, G | 1 |
| Calvani, M | 1 |
| Reda, E | 1 |
| Driedzic, W | 1 |
| Gürlek, A | 1 |
| Tutar, E | 1 |
| Akçil, E | 1 |
| Dinçer, I | 1 |
| Erol, C | 1 |
| Kocatürk, PA | 1 |
| Oral, D | 1 |
| Nemoto, S | 1 |
| Aoki, M | 1 |
| Dehua, C | 1 |
| Imai, Y | 1 |
| Singh, RB | 1 |
| Aslam, M | 1 |
| Lango, R | 1 |
| Smolenski, RT | 1 |
| Narkiewicz, M | 1 |
| Suchorzewska, J | 1 |
| Lysiak-Szydlowska, W | 1 |
| Hwang, Y | 1 |
| Cifuentes, J | 1 |
| Green, D | 1 |
| Hironaka, Y | 1 |
| Yamazaki, N | 1 |
| Lazzarino, G | 1 |
| Corsico, N | 1 |
| Tavazzi, B | 1 |
| di Pierro, D | 1 |
| Giardina, B | 1 |
| Bertelli, A | 1 |
| Ronca, F | 1 |
| Ronca, G | 1 |
| Palmieri, L | 1 |
| Zucchi, R | 1 |
| Bick, RJ | 1 |
| Benedict, CR | 1 |
| Dubelaar, ML | 1 |
| Shug, AL | 1 |
| Zhao, J | 1 |
| Hogendoorn, A | 1 |
| Di Biase, M | 1 |
| Biasco, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
20 reviews available for carnitine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Ins | 2013 |
Value of carnitine therapy in kidney dialysis patients and effects on cardiac function from human and animal studies.
Topics: Carnitine; Heart; Humans; Kidney Failure, Chronic; Myocardial Ischemia; Myocardium; Renal Dialysis | 2012 |
[An old strategy which comes up again: metabolic therapy of acute myocardial infarction].
Topics: Carnitine; Glucose; Humans; Insulin; Muscle Cells; Myocardial Infarction; Myocardial Ischemia; Potas | 1999 |
Role of metabolically active drugs in the management of ischemic heart disease.
Topics: Acetanilides; Animals; Cardiovascular Agents; Carnitine; Clinical Trials as Topic; Dichloroacetic Ac | 2001 |
[Biochemical mechanisms of mildronate action during ischemic stress].
Topics: Animals; Cardiovascular Agents; Carnitine; Clinical Trials as Topic; Humans; Methylhydrazines; Myoca | 2004 |
Ischemic heart disease: metabolic approaches to management.
Topics: Acetanilides; Cardiovascular Agents; Carnitine; Dichloroacetic Acid; Energy Metabolism; Humans; Myoc | 2004 |
Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review.
Topics: Cardiotonic Agents; Cardiovascular Diseases; Carnitine; Humans; Kidney Failure, Chronic; Liver; Myoc | 2004 |
Metabolic modulators for chronic cardiac ischemia.
Topics: Acetanilides; Animals; Carnitine; Chronic Disease; Drug Evaluation, Preclinical; Enzyme Inhibitors; | 2005 |
Selected metabolic alterations in the ischemic heart and their contributions to arrhythmogenesis.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carnitine; Carnitine O-Palmitoyltransferase; | 1995 |
The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart.
Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Carbohydrate Metabolism; Carnitine; Carnitine O- | 1994 |
Carnitine and cardiac interstitium.
Topics: Animals; Calcium Channels; Carnitine; Heart; Humans; Myocardial Ischemia; Myocardium; Oxygen; Rats | 1994 |
[Preconditioning of the ischemic myocardium].
Topics: Adenosine; Angioplasty, Balloon, Coronary; Animals; Calcium Channel Blockers; Carnitine; Dogs; Elect | 1995 |
Metabolic approach to myocardial ischemia: a novel therapeutic strategy for patients with coronary artery disease?
Topics: Acetanilides; Carnitine; Clinical Trials as Topic; Coenzymes; Coronary Disease; Enzyme Inhibitors; H | 1995 |
Carnitine--from cellular mechanisms to potential clinical applications in heart disease.
Topics: Carnitine; Heart Failure; Humans; Myocardial Ischemia | 1997 |
[Consensus conference on the therapeutic effects of L-carnitine in patients with myocardial ischemia and left ventricular remodeling].
Topics: Carnitine; Coronary Disease; Humans; Myocardial Infarction; Myocardial Ischemia; Ventricular Functio | 1998 |
Regulation of carbohydrate metabolism in ischemia and reperfusion.
Topics: Animals; Carbohydrate Metabolism; Carnitine; Energy Metabolism; Fatty Acids, Nonesterified; Glucose; | 2000 |
Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions.
Topics: Animals; Carbohydrate Metabolism; Carnitine; Fatty Acids; Humans; Myocardial Ischemia; Myocardial Re | 2000 |
Influence of L-carnitine and its derivatives on myocardial metabolism and function in ischemic heart disease and during cardiopulmonary bypass.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Carnitine; Energy Met | 2001 |
New thoughts of pathophysiology and therapy of ischemic heart disease.
Topics: Animals; Carnitine; Heart; Heart Failure; Humans; Myocardial Infarction; Myocardial Ischemia; Myocar | 1991 |
[The role of metabolic therapy in myocardial infarct].
Topics: Adenosine Triphosphate; Animals; Carnitine; Heart; Humans; Lipid Metabolism; Myocardial Infarction; | 1991 |
6 trials available for carnitine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Effect of L-Carnitine Supplementation on Reverse Remodeling in Patients with Ischemic Heart Disease Undergoing Coronary Artery Bypass Grafting: A Randomized, Placebo-Controlled Trial.
Topics: Aged; Body Mass Index; Carnitine; Coronary Artery Bypass; Dietary Supplements; Female; Follow-Up Stu | 2017 |
[The evaluation of the antiarrhythmic activity of L-carnitine and propafenone in ischemic cardiopathy].
Topics: Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Carnitine; Drug Therapy, Combination; El | 1993 |
Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris.
Topics: Aged; Angina Pectoris; Cardiac Output; Cardiotonic Agents; Carnitine; Coronary Disease; Electrocardi | 1994 |
[Therapy of arrhythmia induced by myocardial ischemia. Association of L-carnitine, propafenone and mexiletine].
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Carnitine; Drug Sy | 1995 |
Additional antiischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy.
Topics: Adult; Aged; Angina Pectoris; Carnitine; Exercise Test; Female; Humans; Male; Middle Aged; Myocardia | 1995 |
The effects of L-carnitine treatment on left ventricular function and erythrocyte superoxide dismutase activity in patients with ischemic cardiomyopathy.
Topics: Aged; Carnitine; Erythrocytes; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Superoxide Di | 2000 |
48 other studies available for carnitine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Beneficial Effects of Essential Oils from the Mediterranean Diet on Gut Microbiota and Their Metabolites in Ischemic Heart Disease and Type-2 Diabetes Mellitus.
Topics: Animals; Carnitine; Diabetes Mellitus, Type 2; Diet, Mediterranean; Emulsions; Fatty Acids, Volatile | 2022 |
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Cardiovascular Agents; Carnitin | 2009 |
Pharmacological preconditioning with L-carnitine: relevance to myocardial hemodynamic function and glycogen and lactate content.
Topics: Adenosine Triphosphate; Animals; Carnitine; Glycogen; Hemodynamics; Ischemic Preconditioning, Myocar | 2010 |
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Catalytic Domain; Diabetes Mellitus, Type 2; E | 2011 |
Relative importance of enhanced glucose uptake versus attenuation of long-chain acyl carnitines in protecting ischemic myocardium.
Topics: Animals; Carnitine; Creatine Kinase; Cytochalasin B; Disease Models, Animal; Glucose; Models, Cardio | 2002 |
Endothelium- and nitric oxide-dependent vasorelaxing activities of gamma-butyrobetaine esters: possible link to the antiischemic activities of mildronate.
Topics: Animals; Aorta, Thoracic; Betaine; Carnitine; Ditiocarb; Drug Combinations; Drug Evaluation, Preclin | 2004 |
Effects of propionyl-carnitine on mitochondrial respiration and post-ischaemic cardiac function in the ischaemic underperfused diabetic rat heart.
Topics: Animals; Blood Pressure; Body Weight; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental | 2004 |
Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics.
Topics: Animals; Base Sequence; Cardiomyopathies; Carnitine; Cricetinae; Diabetes Mellitus, Experimental; DN | 2005 |
Inhibition of very long chain acyl-CoA dehydrogenase during cardiac ischemia.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Animals; Carnitine; Cell Respiration; Male; Mitochondria, Muscle | 2005 |
L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Carnitin | 1993 |
Reperfusion-induced accumulation of long-chain acylcarnitines in previously ischemic myocardium.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Epoxy Compounds; Male; Molecular Weight; Myoca | 1993 |
Acylcarnitine accumulation does not correlate with reperfusion recovery in palmitate-perfused rat hearts.
Topics: Acylation; Adenosine Triphosphate; Animals; Blood Pressure; Caproates; Carnitine; Carnitine O-Palmit | 1995 |
Modulation of alpha 1-adrenoceptors in rat left ventricle by ischaemia and acyl carnitines: protection by ranolazine.
Topics: Acetanilides; Animals; Carnitine; Carnitine O-Palmitoyltransferase; Dihydroalprenolol; Dihydropyridi | 1993 |
L-carnitine increases glucose metabolism and mechanical function following ischaemia in diabetic rat heart.
Topics: Animals; Carnitine; Diabetes Mellitus, Experimental; Glucose; Glycolysis; Heart; In Vitro Techniques | 1995 |
[Therapeutic application of myocardial cytoprotection].
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Carnitine; Hum | 1994 |
Evaluation of post-ischemic myocardial metabolism by 1H-magnetic resonance spectroscopy in the rabbit heart.
Topics: Alanine; Animals; Carnitine; Hydrogen; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myoca | 1994 |
Contrasting effects of propionate and propionyl-L-carnitine on energy-linked processes in ischemic hearts.
Topics: Animals; Cardiotonic Agents; Carnitine; Coenzyme A; Energy Metabolism; Esters; In Vitro Techniques; | 1994 |
Metabolic effects of propionate, hexanoate and propionylcarnitine in normoxia, ischaemia and reperfusion. Does an anaplerotic substrate protect the ischaemic myocardium?
Topics: Animals; Caproates; Cardiotonic Agents; Carnitine; Energy Metabolism; Heart; In Vitro Techniques; Ma | 1994 |
Effect of L-carnitine on mitochondrial acyl CoA esters in the ischemic dog heart.
Topics: Animals; Carnitine; Coenzyme A; Dogs; Dose-Response Relationship, Drug; Esters; Male; Mitochondria; | 1994 |
Control of the cardiac consequences of myocardial ischemia and reperfusion by L-propionylcarnitine: age-response and dose-response studies in the rat heart.
Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Carnitine; Coronary Circulation; Dose-Response | 1993 |
Ischemic preconditioning and long-chain acyl carnitine in the canine heart.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Coronary Circulation; Dogs; Myocardial | 1993 |
Cellular uncoupling induced by accumulation of long-chain acylcarnitine during ischemia.
Topics: Animals; Carnitine; Carnitine O-Palmitoyltransferase; Electrophysiology; Epoxy Compounds; Glycine; H | 1994 |
[Cellular electrophysiological basis of proarrhythmic and antiarrhythmic effects of ischemia-related lipid metabolites].
Topics: Animals; Arrhythmias, Cardiac; Carnitine; Electrophysiology; Guinea Pigs; Heart; Lysophosphatidylcho | 1993 |
Beneficial effect of carnitine on mechanical recovery of rat hearts reperfused after a transient period of global ischemia is accompanied by a stimulation of glucose oxidation.
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Carnitine; Esters; Glucose; Glycolysis; Heart; In | 1993 |
Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool.
Topics: Animals; Carnitine; Chromatography, High Pressure Liquid; In Vitro Techniques; Kinetics; Mass Spectr | 1996 |
Release of ischemia in paced rat Langendorff hearts by supply of L-carnitine: role of endogenous long-chain acylcarnitine.
Topics: Aerobiosis; Animals; Cardiac Pacing, Artificial; Carnitine; Cations; Cell Membrane; Cells, Cultured; | 1996 |
On the roles of long-chain acyl carnitine accumulation and impaired glucose utilization in ischaemic contracture development and tissue damage in the guinea-pig heart.
Topics: Animals; Calcium; Carnitine; Cells, Cultured; Chick Embryo; Dose-Response Relationship, Drug; Female | 1996 |
[L-carnitine in the treatment of left ventricular dysfunction in post-infarction].
Topics: Animals; Carnitine; Humans; Myocardial Infarction; Myocardial Ischemia; Ventricular Dysfunction, Lef | 1995 |
Acute myocardial ischaemia induces cardiac carnitine release in man.
Topics: Adult; Aged; Cardiac Pacing, Artificial; Carnitine; Coronary Disease; Female; Hemodynamics; Humans; | 1997 |
Inhibition of carnitine synthesis protects against left ventricular dysfunction in rats with myocardial ischemia.
Topics: Animals; Carnitine; Hypoxia; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Ventricular Dysf | 1997 |
[Effects of L-carnitine on the regional function of the stunned myocardium caused by ischemia of short duration].
Topics: Animals; Carnitine; Coronary Circulation; Dogs; Female; Male; Myocardial Contraction; Myocardial Isc | 1997 |
[The effect of L-carnitine on ischemic heart disease: experimental results].
Topics: Carnitine; Coronary Disease; Fatty Acids; Glucose; Humans; Myocardial Ischemia | 1998 |
[Therapeutic action of L-carnitine in myocardial ischemia and left ventricular remodeling: clinical data].
Topics: Carnitine; Echocardiography; Humans; Hypertrophy, Left Ventricular; Myocardial Infarction; Myocardia | 1998 |
The dose-dependent effects of L-carnitine in myocardial protection in normothermic ischemia.
Topics: Adenosine Deaminase; Analysis of Variance; Animals; Carnitine; Chick Embryo; Disease Models, Animal; | 1998 |
Carnitine supplementation improves myocardial function in hearts from ischemic diabetic and euglycemic rats.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental; Heart; Hemodynamics; In Vitro Te | 1998 |
Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy.
Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Energy Metabolism; Female; Heart; In Vi | 1999 |
Propionyl-L-carnitine effects on postischemic recovery of heart function and substrate oxidation in the diabetic rat.
Topics: Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Glucose; Heart; Male; Myoca | 2000 |
Effects of carnitine on cardiac function after cardioplegic ischemia in neonatal rabbit hearts.
Topics: Animals; Animals, Newborn; Carnitine; Coronary Circulation; Heart; Heart Arrest, Induced; Myocardial | 2001 |
L-carnitine administration in coronary artery disease and cardiomyopathy.
Topics: Carnitine; Coronary Disease; Dietary Supplements; Heart; Humans; Myocardial Ischemia | 1998 |
Protection of ischemic hearts perfused with an anion exchange inhibitor, DIDS, is associated with beneficial changes in substrate metabolism.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anion Exchange Pr | 2001 |
Short-term carnitine deficiency does not alter aerobic rat heart function but depresses reperfusion recovery after ischemia.
Topics: Aerobiosis; Animals; Blood Pressure; Body Weight; Carnitine; Energy Metabolism; Heart; Male; Myocard | 2001 |
Effect of L-carnitine on the cellular distribution of carnitine and its acyl derivatives in the ischemic heart.
Topics: Acylation; Animals; Carnitine; Cytosol; Dogs; Fatty Acids, Nonesterified; Male; Mitochondria, Heart; | 1992 |
[L-propionylcarnitine taurine amide induces the metabolic recovery of the isolated postischemic rat heart].
Topics: Animals; Carnitine; Drug Evaluation, Preclinical; Energy Metabolism; Heart; In Vitro Techniques; Mal | 1992 |
L-carnitine and coenzyme Q10 protective action against ischaemia and reperfusion of working rat heart.
Topics: Animals; Carnitine; Chromatography, High Pressure Liquid; Coenzymes; Drug Combinations; Hemodynamics | 1992 |
Influence of dietary fish oil on mitochondrial function and response to ischemia.
Topics: Animals; Carnitine; Dogs; Electron Transport Complex IV; Fish Oils; Kinetics; Mitochondria, Heart; M | 1992 |
Carnitine requirement of vascular endothelial and smooth muscle cells in imminent ischemia.
Topics: Animals; Carboxy-Lyases; Carnitine; Carnitine O-Acetyltransferase; Cells, Cultured; Endothelium, Vas | 1992 |
Protection of the ischemic diabetic heart by L-propionylcarnitine therapy.
Topics: Animals; Cardiotonic Agents; Carnitine; Diabetes Mellitus, Experimental; Male; Myocardial Contractio | 1992 |
L-propionylcarnitine and myocardial performance in stunned porcine myocardium.
Topics: Animals; Cardiotonic Agents; Carnitine; Female; Hemodynamics; Male; Myocardial Contraction; Myocardi | 1992 |