carnitine has been researched along with Genetic Predisposition in 30 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carnitine is an amino acid derivative, which plays several important roles in human physiology, in the central nervous system, and for mitochondrial metabolism, in particular." | 6.61 | Effects of l-Carnitine in Patients with Autism Spectrum Disorders: Review of Clinical Studies. ( Cauli, O; Malaguarnera, M, 2019) |
| "In women, tooth loss was associated with genotype TT vs." | 5.62 | Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men. ( Grube, M; Jedlitschky, G; Kocher, T; Meisel, P; Pagels, S; Völzke, H, 2021) |
| "The aim of this study was to estimate the effect of carnitine supplementation on lipid disorders and peripheral tissue insulin sensitivity in a non-obese animal model of insulin resistance, the hereditary hypertriglyceridemic (HHTg) rat." | 3.81 | Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. ( Cahova, M; Chrastina, P; Drahota, Z; Hansikova, H; Kazdova, L; Malinska, H; Oliyarnyk, O; Palenickova, E; Papackova, Z; Skop, V; Spacilova, J; Trnovska, J, 2015) |
| " At 4 weeks after ascending aortic constriction, jvs/+ mice showed an exaggeration of cardiac hypertrophy and pulmonary congestion, further increased gene expression of atrial natriuretic peptide in the left ventricles, further deterioration of left ventricular fractional shortening, reduced myocardial phosphocreatine:adenosine triphosphate ratio, and increased mortality compared with wild-type mice; l-carnitine supplementation prevented these changes in jvs/+ mice subjected to ascending aortic constriction." | 3.74 | Pressure overload-induced cardiomyopathy in heterozygous carrier mice of carnitine transporter gene mutation. ( Asai, T; Matsui, H; Murakami, H; Murakami, R; Murohara, T; Numaguchi, Y; Okumura, K; Takahashi, R; Tsuzuki, M, 2007) |
| "Riboflavin treatment resulted in a decrease in EMA excretion in the mut/var group and in a subjective clinical improvement in four patients from this group." | 2.75 | Flavin adenine dinucleotide status and the effects of high-dose riboflavin treatment in short-chain acyl-CoA dehydrogenase deficiency. ( Duran, M; van Maldegem, BT; Wanders, RJ; Waterham, HR; Wijburg, FA, 2010) |
| "Carnitine is an amino acid derivative, which plays several important roles in human physiology, in the central nervous system, and for mitochondrial metabolism, in particular." | 2.61 | Effects of l-Carnitine in Patients with Autism Spectrum Disorders: Review of Clinical Studies. ( Cauli, O; Malaguarnera, M, 2019) |
| "Free carnitine was lower among ε4 carriers than ε3 homozygotes." | 1.72 | Using lipid profiling to better characterize metabolic differences in apolipoprotein E (APOE) genotype among community-dwelling older Black men. ( Boudreau, RM; Marron, MM; Miljkovic, I; Moore, SC; Newman, AB; Sekikawa, A; Wendell, SG, 2022) |
| "In women, tooth loss was associated with genotype TT vs." | 1.62 | Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men. ( Grube, M; Jedlitschky, G; Kocher, T; Meisel, P; Pagels, S; Völzke, H, 2021) |
| "The number of people affected by Type 2 diabetes mellitus (T2DM) is close to half a billion and is on a sharp rise, representing a major and growing public health burden." | 1.62 | Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes. ( Bararpour, N; Darrous, L; Froguel, P; Gasser, M; Gilardi, F; Kutalik, Z; Marques-Vidal, P; Porcu, E; Thomas, A; Waeber, G; Yengo, L, 2021) |
| "The pregnancy was uneventful and the delivery at term." | 1.36 | Treatment of cobalamin C (cblC) deficiency during pregnancy. ( Brunel-Guitton, C; Costa, T; Lambert, M; Mitchell, GA, 2010) |
| "The carnitine ester profile was determined using ESI triple quadrupole tandem MS." | 1.34 | Plasma carnitine ester profiles in Crohn's disease patients characterized for SLC22A4 C1672T and SLC22A5 G-207C genotypes. ( Bene, J; Figler, M; Gasztonyi, B; Horváth, K; Komlósi, K; Magyari, L; Melegh, B; Miheller, P; Mózsik, G; Talián, G; Tulassay, Z, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 17 (56.67) | 24.3611 |
| 2020's | 6 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gélinas, R | 1 |
| Leach, E | 1 |
| Horvath, G | 1 |
| Laksman, Z | 1 |
| Chai, JF | 1 |
| Raichur, S | 1 |
| Khor, IW | 1 |
| Torta, F | 1 |
| Chew, WS | 1 |
| Herr, DR | 1 |
| Ching, J | 1 |
| Kovalik, JP | 1 |
| Khoo, CM | 1 |
| Wenk, MR | 1 |
| Tai, ES | 1 |
| Sim, X | 1 |
| Malaguarnera, M | 1 |
| Cauli, O | 1 |
| McClain, LL | 1 |
| Shaw, P | 1 |
| Sabol, R | 1 |
| Chedia, AM | 1 |
| Segretti, AM | 1 |
| Rengasamy, M | 1 |
| Finegold, DN | 1 |
| Pan, L | 1 |
| Peters, DG | 1 |
| Meisel, P | 1 |
| Pagels, S | 1 |
| Grube, M | 1 |
| Jedlitschky, G | 1 |
| Völzke, H | 1 |
| Kocher, T | 1 |
| Zhuang, Z | 1 |
| Gao, M | 1 |
| Yang, R | 1 |
| Liu, Z | 1 |
| Cao, W | 1 |
| Huang, T | 1 |
| Porcu, E | 1 |
| Gilardi, F | 1 |
| Darrous, L | 1 |
| Yengo, L | 1 |
| Bararpour, N | 1 |
| Gasser, M | 1 |
| Marques-Vidal, P | 1 |
| Froguel, P | 1 |
| Waeber, G | 1 |
| Thomas, A | 1 |
| Kutalik, Z | 1 |
| Marron, MM | 1 |
| Moore, SC | 1 |
| Wendell, SG | 1 |
| Boudreau, RM | 1 |
| Miljkovic, I | 1 |
| Sekikawa, A | 1 |
| Newman, AB | 1 |
| Karlíková, R | 1 |
| Široká, J | 1 |
| Mech, M | 1 |
| Friedecký, D | 1 |
| Janečková, H | 1 |
| Mádrová, L | 1 |
| Hrdinová, F | 1 |
| Drábková, Z | 1 |
| Dobešová, O | 1 |
| Adam, T | 1 |
| Jahn, P | 1 |
| Ferdinandusse, S | 1 |
| Te Brinke, H | 1 |
| Ruiter, JPN | 1 |
| Haasjes, J | 1 |
| Oostheim, W | 1 |
| van Lenthe, H | 1 |
| IJlst, L | 1 |
| Ebberink, MS | 1 |
| Wanders, RJA | 1 |
| Vaz, FM | 1 |
| Waterham, HR | 3 |
| Cahova, M | 1 |
| Chrastina, P | 1 |
| Hansikova, H | 1 |
| Drahota, Z | 1 |
| Trnovska, J | 1 |
| Skop, V | 1 |
| Spacilova, J | 1 |
| Malinska, H | 1 |
| Oliyarnyk, O | 1 |
| Papackova, Z | 1 |
| Palenickova, E | 1 |
| Kazdova, L | 1 |
| Qian, GL | 1 |
| Hong, F | 1 |
| Tong, F | 1 |
| Fu, HD | 1 |
| Liu, AM | 1 |
| Liang, WC | 1 |
| Ohkuma, A | 1 |
| Hayashi, YK | 1 |
| López, LC | 1 |
| Hirano, M | 1 |
| Nonaka, I | 1 |
| Noguchi, S | 1 |
| Chen, LH | 1 |
| Jong, YJ | 1 |
| Nishino, I | 1 |
| Eminoglu, FT | 1 |
| Ozcelik, AA | 1 |
| Okur, I | 1 |
| Tumer, L | 1 |
| Biberoglu, G | 1 |
| Demir, E | 1 |
| Hasanoglu, A | 1 |
| Baumgartner, MR | 1 |
| van Maldegem, BT | 2 |
| Duran, M | 2 |
| Wanders, RJ | 3 |
| Wijburg, FA | 2 |
| Koizumi, A | 1 |
| Catanzano, F | 1 |
| Ombrone, D | 1 |
| Di Stefano, C | 1 |
| Rossi, A | 1 |
| Nosari, N | 1 |
| Scolamiero, E | 1 |
| Tandurella, I | 1 |
| Frisso, G | 1 |
| Parenti, G | 1 |
| Ruoppolo, M | 1 |
| Andria, G | 1 |
| Salvatore, F | 1 |
| Vilarinho, L | 1 |
| Rocha, H | 1 |
| Sousa, C | 1 |
| Marcão, A | 1 |
| Fonseca, H | 1 |
| Bogas, M | 1 |
| Osório, RV | 1 |
| Footitt, EJ | 1 |
| Stafford, J | 1 |
| Dixon, M | 1 |
| Burch, M | 1 |
| Jakobs, C | 1 |
| Salomons, GS | 1 |
| Cleary, MA | 1 |
| Al-Hassnan, ZN | 1 |
| Imtiaz, F | 1 |
| Al-Amoudi, M | 1 |
| Rahbeeni, Z | 1 |
| Al-Sayed, M | 1 |
| Al-Owain, M | 1 |
| Al-Zaidan, H | 1 |
| Al-Odaib, A | 1 |
| Rashed, MS | 1 |
| Brunel-Guitton, C | 1 |
| Costa, T | 1 |
| Mitchell, GA | 1 |
| Lambert, M | 1 |
| Dessein, AF | 1 |
| Fontaine, M | 1 |
| Andresen, BS | 1 |
| Gregersen, N | 1 |
| Brivet, M | 1 |
| Rabier, D | 1 |
| Napuri-Gouel, S | 1 |
| Dobbelaere, D | 1 |
| Mention-Mulliez, K | 1 |
| Martin-Ponthieu, A | 1 |
| Briand, G | 1 |
| Millington, DS | 1 |
| Vianey-Saban, C | 1 |
| Vamecq, J | 1 |
| Wang, F | 1 |
| Han, L | 1 |
| Yang, Y | 1 |
| Gu, X | 1 |
| Ye, J | 1 |
| Qiu, W | 1 |
| Zhang, H | 1 |
| Zhang, Y | 1 |
| Gao, X | 1 |
| Wang, Y | 1 |
| Kim, SH | 1 |
| Park, HD | 1 |
| Sohn, YB | 1 |
| Park, SW | 1 |
| Cho, SY | 1 |
| Ji, S | 1 |
| Kim, SJ | 1 |
| Choi, EW | 1 |
| Kim, CH | 1 |
| Ko, AR | 1 |
| Yeau, S | 1 |
| Paik, KH | 1 |
| Jin, DK | 1 |
| Mak, CM | 1 |
| Lam, CW | 1 |
| Fong, NC | 1 |
| Siu, WK | 1 |
| Lee, HC | 1 |
| Siu, TS | 1 |
| Lai, CK | 1 |
| Law, CY | 1 |
| Tong, SF | 1 |
| Poon, WT | 1 |
| Lam, DS | 1 |
| Ng, HL | 1 |
| Yuen, YP | 1 |
| Tam, S | 1 |
| Que, TL | 1 |
| Kwong, NS | 1 |
| Chan, AY | 1 |
| van der Vlies, M | 1 |
| van Woerden, CS | 1 |
| Bobu, LL | 1 |
| Bene, J | 1 |
| Komlósi, K | 1 |
| Magyari, L | 1 |
| Talián, G | 1 |
| Horváth, K | 1 |
| Gasztonyi, B | 1 |
| Miheller, P | 1 |
| Figler, M | 1 |
| Mózsik, G | 1 |
| Tulassay, Z | 1 |
| Melegh, B | 1 |
| Takahashi, R | 1 |
| Asai, T | 1 |
| Murakami, H | 1 |
| Murakami, R | 1 |
| Tsuzuki, M | 1 |
| Numaguchi, Y | 1 |
| Matsui, H | 1 |
| Murohara, T | 1 |
| Okumura, K | 1 |
| Sharma, AP | 1 |
| Greenberg, CR | 1 |
| Prasad, AN | 1 |
| Prasad, C | 1 |
| Samuraki, M | 1 |
| Komai, K | 1 |
| Hasegawa, Y | 1 |
| Kimura, M | 1 |
| Yamaguchi, S | 1 |
| Terada, N | 1 |
| Yamada, M | 1 |
3 reviews available for carnitine and Genetic Predisposition
| Article | Year |
|---|---|
Effects of l-Carnitine in Patients with Autism Spectrum Disorders: Review of Clinical Studies.
Topics: Autism Spectrum Disorder; Carnitine; Comorbidity; Dose-Response Relationship, Drug; Genetic Predispo | 2019 |
Recurrent rhabdomyolysis and glutaric aciduria type I: a case report and literature review.
Topics: Amino Acid Metabolism, Inborn Errors; Biopsy, Needle; Brain Diseases, Metabolic; Carnitine; Child, P | 2016 |
[Toward a more rational field-genetic epidemiology].
Topics: Animals; Carnitine; Case-Control Studies; Chromosome Mapping; Cloning, Molecular; Diabetes Mellitus; | 2010 |
1 trial available for carnitine and Genetic Predisposition
| Article | Year |
|---|---|
Flavin adenine dinucleotide status and the effects of high-dose riboflavin treatment in short-chain acyl-CoA dehydrogenase deficiency.
Topics: Adolescent; Biomarkers; Butyryl-CoA Dehydrogenase; Carnitine; Child; Child, Preschool; Female; Flavi | 2010 |
26 other studies available for carnitine and Genetic Predisposition
| Article | Year |
|---|---|
Molecular Autopsy Implicates Primary Carnitine Deficiency in Sudden Unexplained Death and Reversible Short QT Syndrome.
Topics: Adult; Autopsy; Cardiomyopathies; Carnitine; Death, Sudden, Cardiac; DNA; Fatal Outcome; Female; Gen | 2019 |
Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases.
Topics: Alzheimer Disease; Asian People; ATP-Binding Cassette Transporters; Carnitine; China; DNA-Binding Pr | 2020 |
Rare variants and biological pathways identified in treatment-refractory depression.
Topics: Adolescent; Adult; Alleles; Biopterins; Carnitine; Computer Simulation; Depressive Disorder, Treatme | 2020 |
Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men.
Topics: Adiposity; Adult; Aged; Aged, 80 and over; Carnitine; Female; Follow-Up Studies; Genetic Predisposit | 2021 |
Causal relationships between gut metabolites and Alzheimer's disease: a bidirectional Mendelian randomization study.
Topics: Alzheimer Disease; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Genetic Predisp | 2021 |
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
Topics: Adult; Aged; Betaine; Biomarkers; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Early | 2021 |
Using lipid profiling to better characterize metabolic differences in apolipoprotein E (APOE) genotype among community-dwelling older Black men.
Topics: Aged; Aged, 80 and over; Apolipoproteins E; Black People; Carnitine; Cholesterol Esters; Fatty Acids | 2022 |
Newborn foal with atypical myopathy.
Topics: Animals; Animals, Newborn; Carnitine; Genetic Predisposition to Disease; Horse Diseases; Horses; Mus | 2018 |
A mutation creating an upstream translation initiation codon in SLC22A5 5'UTR is a frequent cause of primary carnitine deficiency.
Topics: 5' Untranslated Regions; Alleles; Amino Acid Sequence; Base Sequence; Biological Transport; Cardiomy | 2019 |
Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats.
Topics: Animals; Carnitine; Dietary Supplements; DNA, Mitochondrial; Gene Expression Regulation; Genetic Pre | 2015 |
ETFDH mutations, CoQ10 levels, and respiratory chain activities in patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
Topics: Adult; Age of Onset; Asian People; Carnitine; Child; DNA Mutational Analysis; Electron Transport; El | 2009 |
3-Methylcrotonyl-CoA carboxylase deficiency: phenotypic variability in a family.
Topics: Adult; Brain; Carbon-Carbon Ligases; Carnitine; Cells, Cultured; Child, Preschool; DNA Mutational An | 2009 |
The first case of mitochondrial acetoacetyl-CoA thiolase deficiency identified by expanded newborn metabolic screening in Italy: the importance of an integrated diagnostic approach.
Topics: Acetyl-CoA C-Acetyltransferase; Acetyl-CoA C-Acyltransferase; Amino Acid Metabolism, Inborn Errors; | 2010 |
Four years of expanded newborn screening in Portugal with tandem mass spectrometry.
Topics: Amino Acids; Biomarkers; Carnitine; Early Diagnosis; False Positive Reactions; Genetic Predispositio | 2010 |
Use of a long-chain triglyceride-restricted/medium-chain triglyceride-supplemented diet in a case of malonyl-CoA decarboxylase deficiency with cardiomyopathy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Carboxy-Lyases; Cardiomyopathies; Carnitine; Ch | 2010 |
Medium-chain acyl-CoA dehydrogenase deficiency in Saudi Arabia: incidence, genotype, and preventive implications.
Topics: Acyl-CoA Dehydrogenase; Biomarkers; Carnitine; DNA Mutational Analysis; Dried Blood Spot Testing; Fo | 2010 |
Treatment of cobalamin C (cblC) deficiency during pregnancy.
Topics: Amino Acid Metabolism, Inborn Errors; Aspirin; Carnitine; Carrier Proteins; Cells, Cultured; Combine | 2010 |
A novel mutation of the ACADM gene (c.145C>G) associated with the common c.985A>G mutation on the other ACADM allele causes mild MCAD deficiency: a case report.
Topics: Acyl-CoA Dehydrogenase; Adult; Carnitine; Cells, Cultured; Child, Preschool; Deficiency Diseases; Fa | 2010 |
Clinical, biochemical, and molecular analysis of combined methylmalonic acidemia and hyperhomocysteinemia (cblC type) in China.
Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; Carnitine; Carrier Proteins; Child, Preschool; Chi | 2010 |
Mutations of ACADS gene associated with short-chain acyl-coenzyme A dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Base Sequence; Carnitine; DNA Mutational Analysis; Female; Genetic Predispos | 2011 |
Fatal viral infection-associated encephalopathy in two Chinese boys: a genetically determined risk factor of thermolabile carnitine palmitoyltransferase II variants.
Topics: Amino Acid Substitution; Base Sequence; Carnitine; Carnitine O-Palmitoyltransferase; Child, Preschoo | 2011 |
The 625G>A SCAD gene variant is common but not associated with increased C4-carnitine in newborn blood spots.
Topics: Alleles; Butyryl-CoA Dehydrogenase; Carnitine; Fatty Acids; Genetic Predisposition to Disease; Genet | 2005 |
Plasma carnitine ester profiles in Crohn's disease patients characterized for SLC22A4 C1672T and SLC22A5 G-207C genotypes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carnitine; Crohn Disease; Esters; Female; Gene Frequency | 2007 |
Pressure overload-induced cardiomyopathy in heterozygous carrier mice of carnitine transporter gene mutation.
Topics: Adenosine Triphosphate; Animals; Aorta; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Car | 2007 |
Hemolytic uremic syndrome (HUS) secondary to cobalamin C (cblC) disorder.
Topics: Acute Kidney Injury; Betaine; Brain Diseases, Metabolic, Inborn; Carnitine; Carrier Proteins; Combin | 2007 |
A successfully treated adult patient with L-2-hydroxyglutaric aciduria.
Topics: Adult; Age Factors; Alcohol Oxidoreductases; Brain; Brain Diseases, Metabolic; Brain Diseases, Metab | 2008 |