carnitine has been researched along with Fatty Liver in 82 studies
Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To develop a therapeutic agent for obesity-related metabolic disorders, a mixture of dietary components was prepared, including grape extract, green tea extract and l-carnitine (RGTC), and its effects on obesity, hyperlipidemia and non-alcoholic fatty liver disease examined." | 7.77 | A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, K; Lee, KH; Lee, WK; Ly, SY; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| "In the present study, we examined the effect of a mixture of dietary components, including red grape extract, soy isoflavone and L-carnitine (RISC), on obesity." | 7.77 | Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, HS; Lee, K; Lee, KH; Lee, WK; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| "Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency is a mitochondrial fatty acid beta-oxidation defect characterized by accumulation of long-chain hydroxyacylcarnitine intermediates and female carriers of this disorder are in risk for pregnancy complications." | 7.76 | Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication? ( Eskelin, PM; Laitinen, KA; Tyni, TA, 2010) |
| "We recently reported that fatty liver and hypertriglyceridemia are easily induced by the administration of an inhibitor of fatty acid oxidation (emeriamine; (R)-3-amino-4-trimethylaminobutyric acid) to fasting rats, and that these conditions are not accompanied by the increased de novo synthesis of fatty acid [J." | 7.69 | Effects of refeeding diets on emeriamine-induced fatty liver in fasting rats. ( Fujiwara, M; Fukuda, N; Hamamoto, H; Maeda, H; Miyamoto, K, 1996) |
| "The effects of 4-pentenoic acid, a chemical claimed to induce fatty liver morphologically similar to that seen in Reye's syndrome, on carnitine metabolism and on hepatic histology were studied." | 7.68 | Carnitine metabolism in rats with 4-pentenoic acid induced fatty liver. ( Yuge, K, 1990) |
| "In carnitine treatment group, ALT, AST, and total bilirubin were reduced after medication." | 6.75 | Effects of carnitine on peripheral blood mitochondrial DNA copy number and liver function in non-alcoholic fatty liver disease. ( Chae, JD; Cho, WK; Jang, SS; Jun, DW; Jun, JH; Lim, CY, 2010) |
| "Obesity is increasing rapidly across the globe." | 5.62 | Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats. ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
| "L-carnitine is a compound known to transport fatty acids into the mitochondria to enhance β-oxidation-mediated metabolism of fats." | 5.46 | Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver. ( Fujisawa, K; Matsumoto, T; Matsuzaki, A; Sakaida, I; Takami, T; Terai, S; Yamamoto, N, 2017) |
| "Systemic carnitine-deficient juvenile visceral steatosis (JVS) mice exhibit decreased expression of some liver-selective genes including those for the urea cycle enzymes during the infantile period." | 5.30 | Suppressed expression of the urea cycle enzyme genes in the liver of carnitine-deficient juvenile visceral steatosis (JVS) mice in infancy and during starvation in adulthood. ( Horiuchi, M; Mori, M; Musa, DA; Saheki, T; Takiguchi, M; Tomomura, A; Tomomura, M, 1997) |
| "The discovery of cardiac hypertrophy in carnitine-deficient jvs mice will lead to clarification of the pathophysiology of cardiomyopathy in systemic carnitine deficiency in human beings." | 5.29 | Cardiac hypertrophy in juvenile visceral steatosis (jvs) mice with systemic carnitine deficiency. ( Hayakawa, J; Horiuchi, M; Kobayashi, K; Koizumi, T; Kuriwaki, K; Kuwajima, M; Nikaido, H; Tomomura, M; Yoshida, H; Yoshimine, K, 1993) |
| "Massive hepatomegaly and steatosis developed in the baby at a time of severe viral respiratory illness, prolonged fasting, hypoglycemia, and hypoketonuria." | 5.28 | Massive hepatomegaly, steatosis, and secondary plasma carnitine deficiency in an infant with cystic fibrosis. ( Stanley, CA; Treem, WR, 1989) |
| "Clinical studies revealed an absence of ketosis on fasting (plasma beta-hydroxybutyrate less than 0." | 5.27 | Medium-chain acyl-CoA dehydrogenase deficiency in children with non-ketotic hypoglycemia and low carnitine levels. ( Baker, L; Coates, PM; Corkey, BE; Gonzales, EL; Hale, DE; Hall, CL; Kelley, RI; Stanley, CA; Williamson, JR; Yang, W, 1983) |
| "To develop a therapeutic agent for obesity-related metabolic disorders, a mixture of dietary components was prepared, including grape extract, green tea extract and l-carnitine (RGTC), and its effects on obesity, hyperlipidemia and non-alcoholic fatty liver disease examined." | 3.77 | A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, K; Lee, KH; Lee, WK; Ly, SY; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| "In the present study, we examined the effect of a mixture of dietary components, including red grape extract, soy isoflavone and L-carnitine (RISC), on obesity." | 3.77 | Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases. ( Han, SB; Kang, JS; Kim, HM; Kim, N; Lee, CW; Lee, HS; Lee, K; Lee, KH; Lee, WK; Park, HK; Park, SK; Yoon, WK; Yun, J, 2011) |
| "Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency is a mitochondrial fatty acid beta-oxidation defect characterized by accumulation of long-chain hydroxyacylcarnitine intermediates and female carriers of this disorder are in risk for pregnancy complications." | 3.76 | Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication? ( Eskelin, PM; Laitinen, KA; Tyni, TA, 2010) |
| "The results showed: i) no difference between the alcohol/no alcohol groups, with or without carnitine, regarding body weight gain, diet consumption, urinary nitrogen excretion, plasma free fatty acids, lysine, methionine, and glycine." | 3.76 | Failure of carnitine in improving hepatic nitrogen content in alcoholic and non-alcoholic malnourished rats. ( Jordão, AA; Marchini, JS; Padovan, GJ; Portari, GV; Rodrigues, LP; Suen, V, 2010) |
| "Rats with carnitine deficiency due to trimethylhydrazinium propionate (mildronate) administered at 80 mg/100 g body weight per day for 10 days developed liver steatosis only upon fasting." | 3.74 | Regulation of lipid flux between liver and adipose tissue during transient hepatic steatosis in carnitine-depleted rats. ( Caverot, L; Clouet, P; Degrace, P; Demizieux, L; Djaouti, L; Du, ZY; Gresti, J; Guilland, JC; Hocquette, JF; Jourdan, T; Moindrot, B, 2007) |
| " Metabolic changes (liver steatosis and loss of muscle glycogen stores) appear also early after carnitine deprivation." | 3.74 | Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency. ( Beier, K; Knapp, AC; Krähenbühl, S; Todesco, L; Torok, M, 2008) |
| " In patients with NASH and control subjects, we measured free carnitine, short-chain acylcarnitine (SCAC) and long-chain acylcarnitine (LCAC) esters, carnitine palmitoyltransferase (CPT) activity, and MRC enzyme activity in liver tissue as well as serum concentration of tumor necrosis factor alpha (TNF-alpha), homeostatic metabolic assessment of insulin resistance (HOMA(IR)), and body mass index (BMI)." | 3.72 | Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. ( Arenas, J; Castellano, G; Colina, F; Del Hoyo, P; Martín, A; Martín, MA; Pérez-Carreras, M; Rubio, JC; Solis-Herruzo, JA, 2003) |
| "L-carnitine represents a feasible metabolic adjunct for a safe and more successful preservation of ischemia-reperfusion-sensitive steatotic livers." | 3.72 | L-carnitine ameliorates abnormal vulnerability of steatotic rat livers to cold ischemic preservation. ( Decker, D; Dombrowski, F; Lauschke, H; Pütz, U; Tolba, RH, 2003) |
| " Treatment with medium chain triglycerides and L-carnitine in the diet improved his hepatomegaly and cardiomegaly." | 3.70 | Milder childhood form of very long-chain acyl-CoA dehydrogenase deficiency in a 6-year-old Japanese boy. ( Abo, W; Doi, T; Fukao, T; Hayashi, K; Hori, T; Nakada, T; Takahashi, Y; Tateno, M; Terada, N, 2000) |
| "Here, we report the case of a 17-year-old girl who presented in both ten months and five years of age a clinical picture characterized by lethargy leading to apnea and coma, hepatomegaly, hypoglycemia, metabolic acidosis, hyperammoniemia, elevated serum transaminases and absence of ketonuria." | 3.70 | [3-hydroxy-3-methylglutaric aciduria and recurrent Reye-like syndrome]. ( Castro-Gago, M; Eirís, J; Fernández-Prieto, R; Ribes, A; Rodríguez-García, J; Rodríguez-Segade, S, 1998) |
| "We recently reported that fatty liver and hypertriglyceridemia are easily induced by the administration of an inhibitor of fatty acid oxidation (emeriamine; (R)-3-amino-4-trimethylaminobutyric acid) to fasting rats, and that these conditions are not accompanied by the increased de novo synthesis of fatty acid [J." | 3.69 | Effects of refeeding diets on emeriamine-induced fatty liver in fasting rats. ( Fujiwara, M; Fukuda, N; Hamamoto, H; Maeda, H; Miyamoto, K, 1996) |
| "We analyzed carnitine profiles in C3H-H-2 degrees strain of mouse associated with fatty liver, hyperammonemia and hypoglycemia (Koizumi et al." | 3.68 | Animal model of systemic carnitine deficiency: analysis in C3H-H-2 degrees strain of mouse associated with juvenile visceral steatosis. ( Hayakawa, J; Horiuchi, M; Imamura, Y; Inui, Y; Kawata, S; Koizumi, T; Kono, N; Kuwajima, M; Ono, A; Saheki, T, 1991) |
| "The effects of 4-pentenoic acid, a chemical claimed to induce fatty liver morphologically similar to that seen in Reye's syndrome, on carnitine metabolism and on hepatic histology were studied." | 3.68 | Carnitine metabolism in rats with 4-pentenoic acid induced fatty liver. ( Yuge, K, 1990) |
| "In patients with NASH and control subjects, we randomly dispensed one 1-g L-carnitine tablet after breakfast plus diet and one 1 g tablet after dinner plus diet for 24 weeks or diet alone at the same dosage and regimen." | 2.75 | L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial. ( Antic, T; Avitabile, T; Galvano, F; Gargante, MP; Li Volti, G; Malaguarnera, M; Russo, C; Vacante, M, 2010) |
| "In carnitine treatment group, ALT, AST, and total bilirubin were reduced after medication." | 2.75 | Effects of carnitine on peripheral blood mitochondrial DNA copy number and liver function in non-alcoholic fatty liver disease. ( Chae, JD; Cho, WK; Jang, SS; Jun, DW; Jun, JH; Lim, CY, 2010) |
| "Choline is a conditionally essential nutrient in this population." | 2.67 | Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. ( Ament, ME; Buchman, AL; Dubin, M; Eckhert, CD; Gornbein, J; Jenden, D; Moukarzel, A; Rice, K; Roch, MH, 1992) |
| "Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disorders ranging from hepatic steatosis [excessive accumulation of triglycerides (TG)] to nonalcoholic steatohepatitis, which can progress to cirrhosis and hepatocellular carcinoma." | 1.62 | ( Abdul Azees, PA; Barnes, JL; Das, F; Ghosh Choudhury, G; Kamat, A; Katz, MS; Pizzini, J; Shi, Y; Wang, H; Weintraub, ST; Yeh, CK; Zang, M, 2021) |
| "Obesity is increasing rapidly across the globe." | 1.62 | Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats. ( Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M, 2021) |
| "L-carnitine is a compound known to transport fatty acids into the mitochondria to enhance β-oxidation-mediated metabolism of fats." | 1.46 | Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver. ( Fujisawa, K; Matsumoto, T; Matsuzaki, A; Sakaida, I; Takami, T; Terai, S; Yamamoto, N, 2017) |
| "4 μg/ml, and for the absorption rate constant 0." | 1.40 | Pharmacokinetic and pharmacological effects of β-hydroxyphosphocarnitine in animal models. ( De la Cruz-Cordero, R; Duarte-Vázquez, MÁ; Mendoza-Rivera, B; Reyes-Esparza, J; Rodríguez-Fragoso, L; Rosado, JL, 2014) |
| "Carnitine treatment increased the mRNA expression of carnitine palmitoyltransferase 1A and peroxisome proliferator-activated receptor-γ, and carnitine-lipoic acid further augmented the mRNA expression." | 1.37 | Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. ( Cho, WK; Choi, HS; Hahm, JS; Jang, KS; Jeon, HJ; Jun, DW; Jun, JH; Kim, HJ; Kwon, HJ; Lee, HL; Lee, KN; Lee, MH; Lee, OY; Yoon, BC, 2011) |
| "Carnitine-deficient juvenile visceral steatosis (JVS) mice, suffering from fatty acid metabolism abnormalities, have reduced locomotor activity after fasting." | 1.35 | Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis (JVS) mice: involvement of defective acyl-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus. ( Asakawa, A; Fujimiya, M; Horiuchi, M; Inui, A; Kato, I; Nakazato, M; Saheki, T; Sakoguchi, T; Takeuchi, T; Ushikai, M; Yoshida, G, 2009) |
| "Therefore, heterozygous juvenile visceral steatosis (jvs)(+/-) mice, an animal model with decreased carnitine stores caused by impaired renal reabsorption of carnitine, and the corresponding wild-type mice were treated with subtoxic oral doses of VPA (0." | 1.35 | Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores. ( Beier, K; Knapp, AC; Krähenbühl, S; Reichen, J; Sägesser, H; Terracciano, L; Todesco, L, 2008) |
| "Antioxidant changes in juvenile visceral steatosis (JVS) mice, a model of heart hypertrophy due to disorder of fatty-acid oxidation, were examined at 4 weeks (developing hypertrophy stage) and 8 weeks of age (established hypertrophy stage)." | 1.31 | Antioxidant changes in the hypertrophied heart due to energy metabolic disorder. ( Hayakawa, T; Hayashi, K; Ito, M; Kamiya, H; Matsui, H; Okumura, K; Saburi, Y, 2001) |
| "Systemic carnitine-deficient juvenile visceral steatosis (JVS) mice exhibit decreased expression of some liver-selective genes including those for the urea cycle enzymes during the infantile period." | 1.30 | Suppressed expression of the urea cycle enzyme genes in the liver of carnitine-deficient juvenile visceral steatosis (JVS) mice in infancy and during starvation in adulthood. ( Horiuchi, M; Mori, M; Musa, DA; Saheki, T; Takiguchi, M; Tomomura, A; Tomomura, M, 1997) |
| "Juvenile visceral steatosis (JVS) mice have been reported to have systemic carnitine deficiency, and the carnitine concentration in the liver of JVS mice was markedly lower than that of controls (11." | 1.30 | The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency. ( Horiuchi, M; Inoue, F; Kinugasa, A; Kizaki, Z; Kodo, N; Nakajima, T; Saheki, T; Sawada, T; Yamanaka, H, 1997) |
| "Juvenile visceral steatosis (JVS) mice, which show systemic L-carnitine deficiency, may be an animal model of Reye's syndrome because of its phenotype of fat deposition and mitochondrial abnormalities in the liver." | 1.30 | Loss of wild-type carrier-mediated L-carnitine transport activity in hepatocytes of juvenile visceral steatosis mice. ( Hashimoto, N; Hayakawa, J; Higashi, Y; Miyamoto, K; Nezu, J; Nikaido, H; Nomura, M; Ohashi, R; Oku, A; Shimane, M; Tamai, I; Tatsumi, Y; Tsuji, A; Yokogawa, K; Yonekawa, M, 1999) |
| "A mouse with juvenile visceral steatosis (the JVS mouse) has been recognized as a novel animal model for systemic carnitine deficiency." | 1.29 | Mitochondrial abnormalities of muscle tissue in mice with juvenile visceral steatosis associated with systemic carnitine deficiency. ( Fujimura, H; Hanafusa, T; Kuwajima, M; Miyagawa, J; Narama, I; Ono, A; Oue, T; Ozaki, K; Uenaka, R; Yamamoto, K, 1995) |
| "Massive obesity is characterized by enhanced fatty acid turnover, insulin resistance, and often a fatty liver." | 1.29 | Increased liver carnitine content in obese women. ( Backman, L; Cederblad, G; Harper, P; Wadström, C, 1995) |
| "The discovery of cardiac hypertrophy in carnitine-deficient jvs mice will lead to clarification of the pathophysiology of cardiomyopathy in systemic carnitine deficiency in human beings." | 1.29 | Cardiac hypertrophy in juvenile visceral steatosis (jvs) mice with systemic carnitine deficiency. ( Hayakawa, J; Horiuchi, M; Kobayashi, K; Koizumi, T; Kuriwaki, K; Kuwajima, M; Nikaido, H; Tomomura, M; Yoshida, H; Yoshimine, K, 1993) |
| "Juvenile visceral steatosis (JVS) mice are associated with systemic carnitine deficiency (Kuwajima, et al." | 1.29 | Carnitine transport defect in fibroblasts of juvenile visceral steatosis (JVS) mouse. ( Hanafusa, T; Harashima, H; Hayakawa, J; Kuwajima, M; Lu, K; Matsuzawa, Y; Miyagawa, J; Mizuno, A; Murakami, T; Nakajima, H; Namba, M; Ono, A; Sato, I; Shima, K, 1996) |
| "Massive hepatomegaly and steatosis developed in the baby at a time of severe viral respiratory illness, prolonged fasting, hypoglycemia, and hypoketonuria." | 1.28 | Massive hepatomegaly, steatosis, and secondary plasma carnitine deficiency in an infant with cystic fibrosis. ( Stanley, CA; Treem, WR, 1989) |
| "Clinical studies revealed an absence of ketosis on fasting (plasma beta-hydroxybutyrate less than 0." | 1.27 | Medium-chain acyl-CoA dehydrogenase deficiency in children with non-ketotic hypoglycemia and low carnitine levels. ( Baker, L; Coates, PM; Corkey, BE; Gonzales, EL; Hale, DE; Hall, CL; Kelley, RI; Stanley, CA; Williamson, JR; Yang, W, 1983) |
| "L-Carnitine treatment blunted the magnitude of the diet induced increase in 7 alpha-hydroxylase activity, yet overall the activity still remained elevated relative to controls." | 1.27 | L-carnitine treatment in the hyperlipidemic rabbit. ( Hahn, P; James, L; Jones, E; Seccombe, DW, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (12.20) | 18.7374 |
| 1990's | 24 (29.27) | 18.2507 |
| 2000's | 20 (24.39) | 29.6817 |
| 2010's | 23 (28.05) | 24.3611 |
| 2020's | 5 (6.10) | 2.80 |
| Authors | Studies |
|---|---|
| Yi, HS | 1 |
| Jiang, T | 1 |
| Zhang, Y | 1 |
| Bai, M | 1 |
| Li, P | 1 |
| Wang, W | 1 |
| Chen, M | 1 |
| Ma, Z | 1 |
| Zeng, S | 1 |
| Zhou, H | 1 |
| Jiang, H | 1 |
| Montesano, A | 1 |
| Senesi, P | 1 |
| Vacante, F | 1 |
| Mollica, G | 1 |
| Benedini, S | 1 |
| Mariotti, M | 1 |
| Luzi, L | 1 |
| Terruzzi, I | 1 |
| Tamai, Y | 1 |
| Chen, Z | 1 |
| Wu, Y | 1 |
| Okabe, J | 1 |
| Kobayashi, Y | 2 |
| Chiba, H | 1 |
| Hui, SP | 1 |
| Eguchi, A | 1 |
| Iwasa, M | 1 |
| Ito, M | 3 |
| Takei, Y | 1 |
| Shi, Y | 1 |
| Pizzini, J | 1 |
| Wang, H | 1 |
| Das, F | 1 |
| Abdul Azees, PA | 1 |
| Ghosh Choudhury, G | 1 |
| Barnes, JL | 1 |
| Zang, M | 1 |
| Weintraub, ST | 1 |
| Yeh, CK | 1 |
| Katz, MS | 1 |
| Kamat, A | 1 |
| Esmail, M | 1 |
| Anwar, S | 1 |
| Kandeil, M | 1 |
| El-Zanaty, AM | 1 |
| Abdel-Gabbar, M | 1 |
| Fujisawa, K | 1 |
| Takami, T | 1 |
| Matsuzaki, A | 1 |
| Matsumoto, T | 1 |
| Yamamoto, N | 1 |
| Terai, S | 1 |
| Sakaida, I | 1 |
| Loomba, R | 1 |
| Kayali, Z | 1 |
| Noureddin, M | 1 |
| Ruane, P | 1 |
| Lawitz, EJ | 1 |
| Bennett, M | 1 |
| Wang, L | 1 |
| Harting, E | 1 |
| Tarrant, JM | 1 |
| McColgan, BJ | 1 |
| Chung, C | 1 |
| Ray, AS | 1 |
| Subramanian, GM | 1 |
| Myers, RP | 1 |
| Middleton, MS | 1 |
| Lai, M | 1 |
| Charlton, M | 1 |
| Harrison, SA | 1 |
| Sato, C | 1 |
| Saito, T | 1 |
| Misawa, K | 1 |
| Katsumi, T | 1 |
| Tomita, K | 1 |
| Ishii, R | 1 |
| Haga, H | 1 |
| Okumoto, K | 1 |
| Nishise, Y | 1 |
| Watanabe, H | 1 |
| Ueno, Y | 1 |
| Kawata, S | 2 |
| Roesmann, A | 1 |
| Afify, M | 1 |
| Panse, J | 1 |
| Eisert, A | 1 |
| Steitz, J | 1 |
| Tolba, RH | 3 |
| Hong, ES | 1 |
| Kim, EK | 1 |
| Kang, SM | 1 |
| Khang, AR | 1 |
| Choi, SH | 1 |
| Park, KS | 1 |
| Jang, HC | 1 |
| Lim, S | 1 |
| Nativ, NI | 1 |
| Yarmush, G | 1 |
| So, A | 1 |
| Barminko, J | 1 |
| Maguire, TJ | 1 |
| Schloss, R | 1 |
| Berthiaume, F | 1 |
| Yarmush, ML | 1 |
| Reyes-Esparza, J | 1 |
| Mendoza-Rivera, B | 1 |
| De la Cruz-Cordero, R | 1 |
| Duarte-Vázquez, MÁ | 1 |
| Rosado, JL | 1 |
| Rodríguez-Fragoso, L | 1 |
| Horiuchi, M | 9 |
| Nakakuma, M | 1 |
| Arimura, E | 1 |
| Ushikai, M | 2 |
| Yoshida, G | 2 |
| Comhair, TM | 1 |
| Garcia Caraballo, SC | 1 |
| Dejong, CH | 1 |
| Lamers, WH | 1 |
| Koehler, SE | 1 |
| Nakamura, M | 1 |
| Matsumoto, H | 1 |
| Nakashima, H | 1 |
| Ando, Y | 1 |
| Hirai, T | 2 |
| Yoshida, K | 1 |
| Hino, K | 1 |
| Banan, B | 1 |
| Watson, R | 1 |
| Xu, M | 1 |
| Lin, Y | 1 |
| Chapman, W | 1 |
| Socha, P | 1 |
| Horvath, A | 1 |
| Vajro, P | 1 |
| Dziechciarz, P | 1 |
| Dhawan, A | 1 |
| Szajewska, H | 1 |
| Sakoguchi, T | 1 |
| Asakawa, A | 1 |
| Fujimiya, M | 1 |
| Kato, I | 1 |
| Nakazato, M | 1 |
| Takeuchi, T | 1 |
| Saheki, T | 7 |
| Inui, A | 1 |
| Malaguarnera, M | 3 |
| Gargante, MP | 2 |
| Russo, C | 1 |
| Antic, T | 1 |
| Vacante, M | 2 |
| Avitabile, T | 1 |
| Li Volti, G | 1 |
| Galvano, F | 1 |
| Eskelin, PM | 1 |
| Laitinen, KA | 1 |
| Tyni, TA | 1 |
| Lim, CY | 1 |
| Jun, DW | 2 |
| Jang, SS | 1 |
| Cho, WK | 2 |
| Chae, JD | 1 |
| Jun, JH | 2 |
| Bouchireb, K | 1 |
| Teychene, AM | 1 |
| Rigal, O | 1 |
| de Lonlay, P | 1 |
| Valayannopoulos, V | 1 |
| Gaudelus, J | 1 |
| Sellier, N | 1 |
| Bonnefont, JP | 1 |
| Brivet, M | 1 |
| de Pontual, L | 1 |
| Rodrigues, LP | 1 |
| Portari, GV | 1 |
| Padovan, GJ | 1 |
| Jordão, AA | 1 |
| Suen, V | 1 |
| Marchini, JS | 1 |
| Kang, JS | 2 |
| Lee, WK | 2 |
| Yoon, WK | 2 |
| Kim, N | 2 |
| Park, SK | 4 |
| Park, HK | 2 |
| Ly, SY | 1 |
| Han, SB | 2 |
| Yun, J | 2 |
| Lee, CW | 2 |
| Lee, K | 2 |
| Lee, KH | 2 |
| Kim, HM | 2 |
| Lee, HS | 1 |
| Bjørndal, B | 1 |
| Burri, L | 1 |
| Wergedahl, H | 1 |
| Svardal, A | 1 |
| Bohov, P | 1 |
| Berge, RK | 1 |
| Kwon, HJ | 1 |
| Jang, KS | 1 |
| Kim, HJ | 1 |
| Jeon, HJ | 1 |
| Lee, KN | 1 |
| Lee, HL | 1 |
| Lee, OY | 1 |
| Yoon, BC | 1 |
| Choi, HS | 1 |
| Hahm, JS | 1 |
| Lee, MH | 1 |
| Anderson, KA | 1 |
| Lin, F | 1 |
| Ribar, TJ | 1 |
| Stevens, RD | 1 |
| Muehlbauer, MJ | 1 |
| Newgard, CB | 1 |
| Means, AR | 1 |
| Brockman, DA | 1 |
| Chen, X | 1 |
| Gallaher, DD | 1 |
| FRITZ, IB | 1 |
| DUPONT, P | 1 |
| GEER, BW | 1 |
| VOVIS, GF | 1 |
| Pérez-Carreras, M | 1 |
| Del Hoyo, P | 1 |
| Martín, MA | 1 |
| Rubio, JC | 1 |
| Martín, A | 1 |
| Castellano, G | 1 |
| Colina, F | 1 |
| Arenas, J | 1 |
| Solis-Herruzo, JA | 1 |
| Pütz, U | 1 |
| Decker, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-0976 in Subjects With Nonalcoholic Steatohepatitis[NCT02856555] | Phase 2 | 127 participants (Actual) | Interventional | 2016-08-08 | Completed | ||
| Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia[NCT05501899] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2023-03-03 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02856555)
Timeframe: First Dose date up to last dose (Week 12) plus 30 days
| Intervention | percentage of participants (Number) |
|---|---|
| Firsocostat 5 mg | 70.6 |
| Firsocostat 20 mg | 71.4 |
| Placebo | 61.5 |
4 reviews available for carnitine and Fatty Liver
| Article | Year |
|---|---|
[Experimental Approach to Analysis of the Relationship between Food Environments and Lifestyle-Related Diseases, Including Cardiac Hypertrophy, Fatty Liver, and Fatigue Symptoms].
Topics: Animals; Beriberi; Cardiomegaly; Carnitine; Disease Models, Animal; Fatigue Syndrome, Chronic; Fatty | 2015 |
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review.
Topics: Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Dietary | 2009 |
Carnitine metabolism in chronic liver disease.
Topics: Animals; Carnitine; Chronic Disease; Fatty Liver; Fatty Liver, Alcoholic; Hepatitis, Viral, Human; H | 1996 |
Abnormal gene expression causing hyperammonemia in carnitine-deficient juvenile visceral steatosis (JVS) mice.
Topics: Ammonia; Animals; Carnitine; Fatty Liver; Gene Expression Regulation, Enzymologic; Genes, Recessive; | 1997 |
6 trials available for carnitine and Fatty Liver
| Article | Year |
|---|---|
GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease.
Topics: Acetyl-CoA Carboxylase; Biomarkers; Carnitine; Double-Blind Method; Elasticity Imaging Techniques; F | 2018 |
Effect of carnitine-orotate complex on glucose metabolism and fatty liver: a double-blind, placebo-controlled study.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Blood Glucose; Carnitine; DNA | 2014 |
L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial.
Topics: Adult; Biomarkers; Carnitine; Double-Blind Method; Fatty Liver; Female; Humans; Male; Middle Aged; V | 2010 |
Effects of carnitine on peripheral blood mitochondrial DNA copy number and liver function in non-alcoholic fatty liver disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Bilirub | 2010 |
L-carnitine treatment reduces steatosis in patients with chronic hepatitis C treated with alpha-interferon and ribavirin.
Topics: Adult; Antiviral Agents; Carnitine; Drug Therapy, Combination; Fatty Liver; Female; Hepatitis C, Chr | 2008 |
Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients.
Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Choline; Choline Deficiency; Fat | 1992 |
72 other studies available for carnitine and Fatty Liver
| Article | Year |
|---|---|
The Role of Carnitine Orotate Complex in Fatty Liver.
Topics: Carnitine; Fatty Liver; Humans | 2021 |
Up-regulation of hepatic fatty acid transporters and inhibition/down-regulation of hepatic OCTN2 contribute to olanzapine-induced liver steatosis.
Topics: Adult; Animals; Antipsychotic Agents; Carnitine; Chemical and Drug Induced Liver Injury; Coenzyme A | 2019 |
L-Carnitine counteracts in vitro fructose-induced hepatic steatosis through targeting oxidative stress markers.
Topics: Biomarkers; Carnitine; Fatty Liver; Fructose; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; O | 2020 |
Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver.
Topics: Amino Acids, Branched-Chain; Animals; Carbon Tetrachloride; Carnitine; Cell Death; Chemical and Drug | 2021 |
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Carnitine; Fatty Liver; Formoterol Fumarate; Gene Expr | 2021 |
Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats.
Topics: Animals; Anti-Obesity Agents; Atherosclerosis; Atorvastatin; Blood Glucose; Body Weight; Carnitine; | 2021 |
Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver.
Topics: Animals; Biomarkers; Body Weight; Carnitine; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fa | 2017 |
Impaired mitochondrial β-oxidation in patients with chronic hepatitis C: relation with viral load and insulin resistance.
Topics: Adult; Aged; Carnitine; Fasting; Fatty Acids; Fatty Liver; Female; Hepatitis C, Chronic; Homeostasis | 2013 |
L-carnitine ameliorates L-asparaginase-induced acute liver toxicity in steatotic rat livers.
Topics: Animals; Asparaginase; Aspartate Aminotransferases; Blood Pressure; Carnitine; Cell Line, Tumor; Che | 2013 |
Elevated sensitivity of macrosteatotic hepatocytes to hypoxia/reoxygenation stress is reversed by a novel defatting protocol.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Carnitine; Cytosol; Fatty Liver; Hepatocytes; Hy | 2014 |
Pharmacokinetic and pharmacological effects of β-hydroxyphosphocarnitine in animal models.
Topics: Administration, Oral; Animals; Area Under Curve; Carnitine; Cholesterol; Fatty Liver; Half-Life; Ins | 2014 |
The odd-carbon medium-chain fatty triglyceride triheptanoin does not reduce hepatic steatosis.
Topics: Acyl-CoA Oxidase; Animals; Blood Glucose; Carnitine; CD36 Antigens; Cholesterol; Diet, High-Fat; Die | 2017 |
L-Carnitine Supplementation Improved Hepatic Steatosis After Pancreatectomy.
Topics: Aged; Aged, 80 and over; Carnitine; Dietary Supplements; Fatty Liver; Female; Humans; Liver; Male; M | 2016 |
Development of a normothermic extracorporeal liver perfusion system toward improving viability and function of human extended criteria donor livers.
Topics: Adult; Aged; Allografts; Biopsy, Large-Core Needle; Carnitine; Donor Selection; Exenatide; Fatty Liv | 2016 |
Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis (JVS) mice: involvement of defective acyl-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus.
Topics: Animals; Carnitine; Corticotropin-Releasing Hormone; Disease Models, Animal; Fasting; Fatty Acids; F | 2009 |
Elevated hydroxyacylcarnitines in a carrier of LCHAD deficiency during acute liver disease of pregnancy - a common feature of the pregnancy complication?
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acute Disease; Adult; Carnitine; Fatty Liver; Female; Humans; Lipi | 2010 |
Post-mortem MRI reveals CPT2 deficiency after sudden infant death.
Topics: Carnitine; Carnitine O-Palmitoyltransferase; Cause of Death; Diagnosis; Fatty Liver; Hepatomegaly; H | 2010 |
Failure of carnitine in improving hepatic nitrogen content in alcoholic and non-alcoholic malnourished rats.
Topics: Alcoholism; Animals; Carnitine; Dietary Supplements; Ethanol; Fatty Acids, Nonesterified; Fatty Live | 2010 |
A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice.
Topics: Adipose Tissue; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carnitine; | 2011 |
Improvement of high-fat diet-induced obesity by a mixture of red grape extract, soy isoflavone and L-carnitine: implications in cardiovascular and non-alcoholic fatty liver diseases.
Topics: Animals; Cardiovascular Diseases; Carnitine; Dietary Fats; Fatty Liver; Glycine max; Isoflavones; Li | 2011 |
Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα.
Topics: Adipose Tissue, White; Animals; Anti-Inflammatory Agents; Carnitine; Cytokines; Diet, High-Fat; Diet | 2012 |
Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Carnitine; Carnitine O-Palmitoyltransferase; Choline Def | 2011 |
Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse.
Topics: Adenylate Kinase; Animals; Antigens, Neoplasm; Blood Glucose; Calcium-Calmodulin-Dependent Protein K | 2012 |
Consumption of a high β-glucan barley flour improves glucose control and fatty liver and increases muscle acylcarnitines in the Zucker diabetic fatty rat.
Topics: Adiponectin; Animals; beta-Glucans; Blood Glucose; Body Weight; Carnitine; Cholesterol; Diabetes Mel | 2013 |
Ineffectiveness of carnitine as a choline substitute in the prevention of fatty livers of rats maintained on a choline-deficient diet.
Topics: Animals; Carnitine; Choline; Choline Deficiency; Diet; Fatty Liver; Folic Acid; Rats; Vitamin B Comp | 1957 |
THE EFFECTS OF CHOLINE AND RELATED COMPOUNDS ON THE GROWTH AND DEVELOPMENT OF DROSOPHILA MELANOGASTER.
Topics: Amino Acids; Amino Alcohols; Ammonium Compounds; Animals; Betaine; Carnitine; Chemical Phenomena; Ch | 1965 |
Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis.
Topics: Adult; Body Mass Index; Carnitine; Electron Transport; Fatty Acids; Fatty Liver; Female; Humans; Ins | 2003 |
L-carnitine ameliorates abnormal vulnerability of steatotic rat livers to cold ischemic preservation.
Topics: Alanine Transaminase; Animals; Carnitine; Fatty Liver; Glucose; Glutamate Dehydrogenase; Ischemia; L | 2003 |
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.
Topics: Animals; Carnitine; Coenzyme A; Dietary Fats; Dietary Sucrose; Fatty Liver; Female; Glycerol-3-Phosp | 2005 |
Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency.
Topics: Animals; Blood Glucose; Cardiomyopathy, Hypertrophic; Carnitine; Cell Membrane; Dietary Fats, Unsatu | 2005 |
[L-carnitine in the treatment of liver diseases].
Topics: Animals; Carnitine; Fatty Liver; Hepatitis, Viral, Human; Humans; Liver Cirrhosis | 2005 |
Combined therapy with PPARalpha agonist and L-carnitine rescues lipotoxic cardiomyopathy due to systemic carnitine deficiency.
Topics: Adenosine Triphosphate; Animals; Cardiomyopathy, Hypertrophic; Carnitine; Diglycerides; Drug Therapy | 2006 |
[Changes in myocardium, skeletal muscle and liver of rats fed carnitine-deficient diet and treated with carnitine optical isomers].
Topics: Animals; Atrophy; Carnitine; Diet; Fatty Liver; Liver; Male; Muscle, Skeletal; Myocardium; Rats; Ste | 2006 |
ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit.
Topics: Adipose Tissue; Animals; Base Sequence; Blotting, Western; Carnitine; Chromosome Mapping; Ethylnitro | 2006 |
Regulation of lipid flux between liver and adipose tissue during transient hepatic steatosis in carnitine-depleted rats.
Topics: Adipose Tissue; Animals; Carnitine; Fatty Acids; Fatty Liver; Gene Expression Regulation; Hepatocyte | 2007 |
Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores.
Topics: Animals; Carnitine; Fatty Liver; Liver; Mice; Mice, Transgenic; Muscle, Skeletal; Tissue Distributio | 2008 |
No mutation was found in the alpha-subunit of the mitochondrial tri-functional protein in one patient with severe acute fatty liver of pregnancy and her relatives.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Adult; Carnitine; Cytosine; Family; Fatty Liver; Female; Guanine; | 2007 |
Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Body Weight; Carnitine; Energy Metabolism; F | 2008 |
Medium-chain acyl-CoA dehydrogenase deficiency in children with non-ketotic hypoglycemia and low carnitine levels.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Carnitine; Child; Child, Preschool; Fasting; Fatty Acids; Fatty | 1983 |
Mitochondrial abnormalities of muscle tissue in mice with juvenile visceral steatosis associated with systemic carnitine deficiency.
Topics: Animals; Carnitine; Fatty Liver; Hyperlipoproteinemias; Mice; Mice, Mutant Strains; Microscopy, Elec | 1995 |
Increased liver carnitine content in obese women.
Topics: Adult; Animals; Carnitine; Fatty Acids; Fatty Liver; Female; Humans; Insulin; Liver; Middle Aged; Mu | 1995 |
Biochemical diagnosis of fatty acid oxidation disorders by metabolite analysis of postmortem liver.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, Long-Chain; Animals; Caprylates; Carnitine; Child, P | 1994 |
Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acute Disease; Adult; Carnitine; Cells, Cultured; Child; Child, Pr | 1994 |
Cardiac hypertrophy in juvenile visceral steatosis (jvs) mice with systemic carnitine deficiency.
Topics: Animals; Cardiomegaly; Carnitine; Cell Nucleus; Cytoplasm; DNA; Fatty Liver; Female; Homozygote; Mal | 1993 |
Carnitine transport defect in fibroblasts of juvenile visceral steatosis (JVS) mouse.
Topics: Animals; Betaine; Biological Transport; Carnitine; Cells, Cultured; Fatty Liver; Fetus; Fibroblasts; | 1996 |
Hypertriglyceridemia and fatty liver of fasting rats after administration of emeriamine.
Topics: Animals; Betaine; Carnitine; Carnitine Acyltransferases; Enzyme Inhibitors; Esterification; Fasting; | 1996 |
Disordered expression of glycolytic and gluconeogenic liver enzymes of juvenile visceral steatosis mice with systemic carnitine deficiency.
Topics: Age Factors; Animals; Blotting, Northern; Carnitine; Disease Models, Animal; Fatty Liver; Fructose-B | 1996 |
Effects of refeeding diets on emeriamine-induced fatty liver in fasting rats.
Topics: Animals; Betaine; Carnitine; Carnitine Acyltransferases; Cholesterol; Dietary Carbohydrates; Dietary | 1996 |
Suppressed expression of the urea cycle enzyme genes in the liver of carnitine-deficient juvenile visceral steatosis (JVS) mice in infancy and during starvation in adulthood.
Topics: Age Factors; Animals; Argininosuccinate Synthase; Basic Helix-Loop-Helix Leucine Zipper Transcriptio | 1997 |
The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency.
Topics: Animals; Butyrates; Butyric Acid; Caprylates; Carnitine; Disease Models, Animal; Fatty Liver; In Vit | 1997 |
Mitochondrial carnitine-acylcarnitine translocase deficiency presenting as sudden neonatal death.
Topics: Adult; Amnion; Breast Feeding; Carnitine; Carnitine Acyltransferases; Carnitine O-Palmitoyltransfera | 1997 |
Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Cells, Cultured; Child; Cloning, Molecular; | 1997 |
Postperfusion energy metabolism of steatotic graft and its relation to early graft viability following liver transplantation.
Topics: Adult; Carnitine; Energy Metabolism; Fatty Liver; Female; Graft Survival; Hepatocyte Growth Factor; | 1998 |
[3-hydroxy-3-methylglutaric aciduria and recurrent Reye-like syndrome].
Topics: Acidosis; Adolescent; Apnea; Carnitine; Coma; Diagnosis, Differential; Fatty Liver; Female; Fibrobla | 1998 |
Loss of wild-type carrier-mediated L-carnitine transport activity in hepatocytes of juvenile visceral steatosis mice.
Topics: 2,4-Dinitrophenol; Animals; Anions; Biological Transport; Carnitine; Carrier Proteins; Cations; Fatt | 1999 |
Late-onset type II glutaric aciduria with massive pericardial effusion associated with severe fatty liver.
Topics: Carnitine; Fatty Liver; Glutarates; Humans; Infant; Male; Metabolism, Inborn Errors; Pericardial Eff | 2000 |
Milder childhood form of very long-chain acyl-CoA dehydrogenase deficiency in a 6-year-old Japanese boy.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Cardiomegaly; Carnitine; Child; Fatty Liver; Heart Failure; Hepa | 2000 |
Effects of L-carnitine-hydrochloride in the cold ischemic preservation of fatty liver grafts.
Topics: Animals; Carnitine; Cold Temperature; Fatty Liver; Glucose; Ischemia; L-Lactate Dehydrogenase; Liver | 2001 |
Antioxidant changes in the hypertrophied heart due to energy metabolic disorder.
Topics: alpha-Tocopherol; Animals; Antioxidants; Blood Pressure; Cardiomegaly; Carnitine; Energy Metabolism; | 2001 |
Prenatal diagnosis of multiple acyl-CoA dehydrogenase deficiency: association with elevated alpha-fetoprotein and cystic renal changes.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; alpha-Fetoproteins; Amniocentesis; Amniotic Fluid; | 2001 |
[Study on therapeutic effect of carnitine on hepatic steatosis caused by total parenteral nutrition in rats].
Topics: Animals; Carnitine; Fatty Liver; Male; Parenteral Nutrition, Total; Random Allocation; Rats; Rats, W | 1999 |
Recurrent hypoglycemia associated with glutaric aciduria type II in an adult.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Carnitine; Fatty Acid Desaturases; Fatty Acids, Noneste | 1979 |
Dietary lysine and carnitine: relation to growth and fatty livers in rats.
Topics: Animals; Body Weight; Carnitine; Cholesterol; Fatty Acids; Fatty Liver; Liver; Lysine; Male; Muscles | 1976 |
Carnitine administration to juvenile visceral steatosis mice corrects the suppressed expression of urea cycle enzymes by normalizing their transcription.
Topics: Aging; Animals; Argininosuccinate Synthase; Blotting, Northern; Body Weight; Carbamoyl-Phosphate Syn | 1992 |
Animal model of systemic carnitine deficiency: analysis in C3H-H-2 degrees strain of mouse associated with juvenile visceral steatosis.
Topics: Aging; Animals; Carnitine; Disease Models, Animal; Fatty Liver; Lipid Metabolism; Liver; Mice; Mice, | 1991 |
The effect of L-carnitine supplementation in 4 pentenoic acid treated rats.
Topics: Ammonia; Animals; Blood Glucose; Carnitine; Disease Models, Animal; Fatty Acids, Monounsaturated; Fa | 1990 |
Carnitine metabolism in rats with 4-pentenoic acid induced fatty liver.
Topics: Animals; Carnitine; Fatty Acids; Fatty Acids, Monounsaturated; Fatty Liver; Liver; Male; Rats; Rats, | 1990 |
Liver function in protein-energy malnutrition measured by cinnamic acid tolerance and benzoic acid tolerance: effect of carnitine supplementation.
Topics: Animals; Benzoates; Benzoic Acid; Carnitine; Cinnamates; Drug Tolerance; Fatty Liver; Kwashiorkor; L | 1989 |
Massive hepatomegaly, steatosis, and secondary plasma carnitine deficiency in an infant with cystic fibrosis.
Topics: Carnitine; Combined Modality Therapy; Cystic Fibrosis; Fatty Liver; Glycine max; Hepatomegaly; Human | 1989 |
L-carnitine therapy in home parenteral nutrition patients with abnormal liver tests and low plasma carnitine concentrations.
Topics: Adult; Biopsy, Needle; Carnitine; Fatty Liver; Female; Home Care Services; Humans; Lipid Metabolism; | 1988 |
L-carnitine treatment in the hyperlipidemic rabbit.
Topics: Animals; Body Weight; Carnitine; Dietary Fats; Fatty Liver; Hyperlipidemias; Hypolipidemic Agents; L | 1987 |
[Effect of choline chloride and (-)-carnitine of the experimental fatty liver in the rat].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carnitine; Choline; Fatty Liver; Liver; Rats | 1965 |