Page last updated: 2024-10-16

carnitine and Dementia

carnitine has been researched along with Dementia in 16 studies

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"The acute effects of intravenously administered L-acetylcarnitine (LAC) were evaluated with single-photon emission computed tomography (SPECT) and 99mTc-hexamethylpropyleneamine oxime in 30 demented patients (21 with a clinical diagnosis of Alzheimer's dementia and 9 with mixed-type dementia)."7.67Single-photon emission computed tomography studies with 99mTc-hexamethylpropyleneamine oxime in dementia: effects of acute administration of L-acetylcarnitine. ( Battistin, L; Borsato, N; Calvani, M; Da Col, C; Dam, M; Ferlin, G; Perlotto, N; Pizzolato, G; Saitta, B, 1989)
"Twenty-nine patients with probable Alzheimer's disease, 18 with mild cognitive impairment of the amnestic type, 24 with subjective memory complaint and 46 healthy subjects were enrolled in the study, and the levels of carnitine and acyl-carnitines were measured by tandem mass spectrometry."5.43Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia. ( Angiolillo, A; Corbi, G; Corso, G; Cristofano, A; Di Costanzo, A; Intrieri, M; La Marca, G; Russo, C; Sapere, N; Scapagnini, G; Vitale, M, 2016)
"We examined prospective associations of TMAO, γ-butyrobetaine, crotonobetaine, carnitine, choline, and betaine with risk of cognitive impairment and dementia among older adults aged 65 years and older in the Cardiovascular Health Study (CHS)."4.12Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study. ( de Oliveira Otto, MC; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; Li, XS; Lopez, O; Mozaffarian, D; Nemet, I; Newman, AB; Siscovick, DS; Tang, WHW; Wang, M; Wang, Z, 2022)
"The acute effects of intravenously administered L-acetylcarnitine (LAC) were evaluated with single-photon emission computed tomography (SPECT) and 99mTc-hexamethylpropyleneamine oxime in 30 demented patients (21 with a clinical diagnosis of Alzheimer's dementia and 9 with mixed-type dementia)."3.67Single-photon emission computed tomography studies with 99mTc-hexamethylpropyleneamine oxime in dementia: effects of acute administration of L-acetylcarnitine. ( Battistin, L; Borsato, N; Calvani, M; Da Col, C; Dam, M; Ferlin, G; Perlotto, N; Pizzolato, G; Saitta, B, 1989)
"Twenty-nine patients with probable Alzheimer's disease, 18 with mild cognitive impairment of the amnestic type, 24 with subjective memory complaint and 46 healthy subjects were enrolled in the study, and the levels of carnitine and acyl-carnitines were measured by tandem mass spectrometry."1.43Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia. ( Angiolillo, A; Corbi, G; Corso, G; Cristofano, A; Di Costanzo, A; Intrieri, M; La Marca, G; Russo, C; Sapere, N; Scapagnini, G; Vitale, M, 2016)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's11 (68.75)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
de Oliveira Otto, MC1
Li, XS1
Wang, Z1
Siscovick, DS1
Newman, AB1
Lai, HTM1
Nemet, I1
Lee, Y1
Wang, M1
Fretts, A1
Lemaitre, RN1
Tang, WHW1
Lopez, O1
Hazen, SL1
Mozaffarian, D1
Cristofano, A1
Sapere, N1
La Marca, G1
Angiolillo, A1
Vitale, M1
Corbi, G1
Scapagnini, G1
Intrieri, M1
Russo, C1
Corso, G1
Di Costanzo, A1
Acierno, G1
Recchia, G2
Zerbini, O1
Fabbri, L1
Neri, M1
Cortelloni, C1
De Vreese, L1
Roncolato, M1
Meneghetti, M1
Bamfi, F1
Girelli, M1
Cipolli, C1
Chiari, G1
Genazzani, E1
Goety, CG1
Tanner, CM1
Cohen, JA1
Thelen, JA1
Carroll, VS1
Klawans, HL1
Fariello, RG1
Passeri, M2
Cucinotta, D2
Bonati, PA2
Iannuccelli, M3
Parnetti, L1
Senin, U1
Garzya, G1
Corallo, D1
Fiore, A1
Lecciso, G1
Petrelli, G1
Zotti, C1
Sinforiani, E1
Mauri, M1
Costa, A1
Merlo, P1
Bono, G1
Nappi, G1
Battistin, L1
Pizzolato, G1
Dam, M1
Da Col, C1
Perlotto, N1
Saitta, B1
Borsato, N1
Calvani, M1
Ferlin, G1
Ciotti, G1
Nolfe, G1

Trials

11 trials available for carnitine and Dementia

ArticleYear
[The use of 1-acetylcarnitine in (presenile and senile) Alzheimer's disease. Preliminary results].
    La Clinica terapeutica, 1983, Apr-30, Volume: 105, Issue:2

    Topics: Acetylcarnitine; Aged; Alzheimer Disease; Carnitine; Clinical Trials as Topic; Dementia; Double-Blin

1983
[Aging of the population: the 2d demographic revolution].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Carnitine; Clinical Trials as Topic; Dementia; Demography;

1990
[Clinical development of a drug for brain aging. Current limitations and future prospects].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Dementia; Diagnosis, Differential; Human

1990
[Methodology of a clinical controlled study of L-acetylcarnitine].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Dementia; Humans; Middle Aged; Multicent

1990
[Center monitoring and management of data bases].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Carnitine; Clinical Trials as Topic; Database Management Systems; Dementia; Humans;

1990
[Effects of L-acetylcarnitine on mental deterioration in the aged: initial results].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Aged; Analysis of Variance; Behavior; Carnitine; Clinical Trials as Topic; Cognitio

1990
[A controlled clinical study on the efficacy of L-acetylcarnitine in the treatment of mild-to-moderate mental deterioration in the aged. Conclusions].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Dementia; Humans; Middle Aged; Multicent

1990
L-acetyl-carnitine in Huntington's disease: double-blind placebo controlled crossover study of drug effects on movement disorder and dementia.
    Movement disorders : official journal of the Movement Disorder Society, 1990, Volume: 5, Issue:3

    Topics: Acetylcarnitine; Adult; Aged; Carnitine; Dementia; Double-Blind Method; Female; Humans; Huntington D

1990
Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:1-2

    Topics: Acetylcarnitine; Aged; Carnitine; Cognition; Dementia; Double-Blind Method; Female; Humans; Male; Ra

1990
Evaluation of the effects of L-acetylcarnitine on senile patients suffering from depression.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:2

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Carnitine; Clinical Trials as Topic; Dementia; Depressive

1990
Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine.
    International journal of clinical pharmacology research, 1988, Volume: 8, Issue:5

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Analysis of Variance; Carnitine; Dementia; Female; Humans;

1988

Other Studies

5 other studies available for carnitine and Dementia

ArticleYear
Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study.
    Journal of Alzheimer's disease : JAD, 2022, Volume: 89, Issue:4

    Topics: Animals; Betaine; Carnitine; Choline; Cognitive Dysfunction; Dementia; Medicare; Methylamines; Unite

2022
Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Aged; Alzheimer Disease; Analysis of Variance; Biomarkers; Body Mass Index; Calibration; Carnitine;

2016
[Methodological premises of statistical analysis of the data].
    La Clinica terapeutica, 1990, Mar-31, Volume: 132, Issue:6 Suppl

    Topics: Acetylcarnitine; Age Factors; Aged; Analysis of Variance; Carnitine; Data Interpretation, Statistica

1990
Neuropsychological changes in demented patients treated with acetyl-L-carnitine.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:1-2

    Topics: Acetylcarnitine; Aged; Brain Ischemia; Carnitine; Dementia; Female; Humans; Male; Middle Aged; Pirac

1990
Single-photon emission computed tomography studies with 99mTc-hexamethylpropyleneamine oxime in dementia: effects of acute administration of L-acetylcarnitine.
    European neurology, 1989, Volume: 29, Issue:5

    Topics: Acetylcarnitine; Aged; Alzheimer Disease; Carnitine; Dementia; Female; Humans; Injections, Intraveno

1989