carnitine has been researched along with Deficiency, Vitamin B in 45 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carnitine deficiency is among the many metabolic disturbances that may contribute to fatigue in patients with cancer." | 9.12 | Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. ( Cruciani, RA; Culliney, B; Dvorkin, E; Esteban-Cruciani, N; Homel, P; Lapin, J; Malamud, S; Portenoy, RK, 2006) |
| "We report management through pregnancy and delivery of a patient with carnitine deficiency who had reduced carnitine transport in fibroblasts, but no mutations in the OCTN2 gene." | 7.74 | Carnitine deficiency in pregnancy. ( Abdenur, JE; Donnelly, CT; Hameed, AB; Wing, DA, 2007) |
| "Carnitine treatment does not always prevent the emergence of serious hepatotoxicity, but it does alleviate valproate-induced hyperammonemia." | 6.39 | Carnitine deficiency in epilepsy: Risk factors and treatment. ( Coulter, DL, 1995) |
| "Carnitine deficiency is among the many metabolic disturbances that may contribute to fatigue in patients with cancer." | 5.12 | Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. ( Cruciani, RA; Culliney, B; Dvorkin, E; Esteban-Cruciani, N; Homel, P; Lapin, J; Malamud, S; Portenoy, RK, 2006) |
| "We report management through pregnancy and delivery of a patient with carnitine deficiency who had reduced carnitine transport in fibroblasts, but no mutations in the OCTN2 gene." | 3.74 | Carnitine deficiency in pregnancy. ( Abdenur, JE; Donnelly, CT; Hameed, AB; Wing, DA, 2007) |
| "Valproic acid (VPA) is a broad-spectrum antiepileptic drug and is usually well tolerated, but rare serious complications may occur in some patients receiving VPA chronically, including haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (VHE)." | 2.43 | Science review: carnitine in the treatment of valproic acid-induced toxicity - what is the evidence? ( Gris, M; Lheureux, PE; Penaloza, A; Zahir, S, 2005) |
| "Carnitine is an amino acid derivative that has a key role in the regulation of fatty acid metabolism and ATP formation." | 2.43 | The use of levo-carnitine in children with renal disease: a review and a call for future studies. ( Belay, B; Esteban-Cruciani, N; Kaskel, FJ; Walsh, CA, 2006) |
| "Patients with chronic cardiac failure (CCF), particularly elderly individuals, have several reasons to be deficient in micronutrients including reduced intake, impaired gastrointestinal absorption and increased losses on the background of increased utilisation due for example to increased oxidative stress." | 2.43 | Micronutrients and their supplementation in chronic cardiac failure. An update beyond theoretical perspectives. ( Clark, AL; Witte, KK, 2006) |
| "If carnitine is a conditionally essential nutrient for the neonate, most neonates on total parenteral nutrition in the United States are not receiving adequate nutritional support." | 2.39 | Carnitine in neonatal nutrition. ( Borum, PR, 1995) |
| "Carnitine treatment does not always prevent the emergence of serious hepatotoxicity, but it does alleviate valproate-induced hyperammonemia." | 2.39 | Carnitine deficiency in epilepsy: Risk factors and treatment. ( Coulter, DL, 1995) |
| "The patients' alcohol dependence ranged from 2 to 30 years (13." | 1.39 | Plasma carnitine concentrations after chronic alcohol intoxication. ( Chojnowska, S; Kępka, A; Konarzewska, E; Ladny, JR; Płudowski, P; Szajda, SD; Szulc, A; Waszkiewicz, N; Zalewska-Szajda, B; Zwierz, K, 2013) |
| "Biotin status was repleted by a mixed general diet plus biotin supplementation." | 1.37 | Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. ( Bogusiewicz, A; Henrich, CL; Horvath, TD; Matthews, NI; Mock, DM; Moran, JH; Spencer, HJ; Stratton, SL, 2011) |
| "Carnitine is an essential cofactor for the mitochondrial beta-oxidation of long-chain fatty acids." | 1.30 | A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse. ( Kuwajima, M; Lu, Km; Nakamura, Y; Nishimori, H; Shima, K, 1998) |
| "Carnitine deficiency was suspected in study participants prior to data collection because of previously reported cardiac symptoms, muscle weakness, hypometabolism and/or cachexia." | 1.28 | L-carnitine deficiency in AIDS patients. ( De Simone, C; Jirillo, E; Martelli, EA; Marzo, A; Tzantzoglou, S; Vullo, V, 1992) |
| "Carnitine deficiency has been claimed to be responsible for the myo- and cardio-myopathy observed in dialysis patients and has been attributed to the loss of carnitine during dialysis." | 1.27 | Quantitative assessment of carnitine loss during hemodialysis and hemofiltration. ( Becker, K; Eisenhauer, T; Fuchs, C; Köthe, U; Leschke, M; Rumpf, KW; Scheler, F, 1983) |
| "Treatment with prednisone resulted in clinical improvement but no change in muscle histology." | 1.25 | Hereditary carnitine deficiency of muscle. ( Dimauro, S; Griggs, RC; Markesbery, W; VanDyke, DH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (22.22) | 18.7374 |
| 1990's | 14 (31.11) | 18.2507 |
| 2000's | 11 (24.44) | 29.6817 |
| 2010's | 10 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ono, H | 2 |
| Kępka, A | 1 |
| Waszkiewicz, N | 1 |
| Zalewska-Szajda, B | 1 |
| Chojnowska, S | 1 |
| Płudowski, P | 1 |
| Konarzewska, E | 1 |
| Szulc, A | 1 |
| Ladny, JR | 1 |
| Zwierz, K | 1 |
| Szajda, SD | 1 |
| Zhang, W | 1 |
| Miao, J | 1 |
| Zhang, G | 1 |
| Liu, R | 1 |
| Zhang, D | 1 |
| Wan, Q | 1 |
| Yu, Y | 1 |
| Zhao, G | 1 |
| Li, Z | 1 |
| Crentsil, V | 1 |
| Schürch, R | 1 |
| Todesco, L | 1 |
| Novakova, K | 1 |
| Mevissen, M | 1 |
| Stieger, B | 1 |
| Krähenbühl, S | 1 |
| Stratton, SL | 1 |
| Horvath, TD | 1 |
| Bogusiewicz, A | 1 |
| Matthews, NI | 1 |
| Henrich, CL | 1 |
| Spencer, HJ | 1 |
| Moran, JH | 1 |
| Mock, DM | 1 |
| Fortin, G | 1 |
| Poulsen, SD | 1 |
| Lund, AM | 1 |
| Christensen, E | 1 |
| Skovby, F | 1 |
| Zolkipli, Z | 1 |
| Mai, L | 1 |
| Lamhonwah, AM | 1 |
| Tein, I | 1 |
| Budner, M | 1 |
| Surowiec, Z | 1 |
| Fudalej, P | 1 |
| Hozyasz, KK | 1 |
| FRAENKEL, GS | 1 |
| Kasturi, L | 1 |
| Sawant, SP | 1 |
| Lheureux, PE | 1 |
| Penaloza, A | 1 |
| Zahir, S | 1 |
| Gris, M | 1 |
| Belay, B | 1 |
| Esteban-Cruciani, N | 2 |
| Walsh, CA | 1 |
| Kaskel, FJ | 1 |
| Jalil, MA | 1 |
| Horiuchi, M | 1 |
| Wakamatsu, M | 1 |
| Li, MX | 1 |
| Begum, L | 1 |
| Suzuki, K | 1 |
| Kobayashi, K | 1 |
| Oka, T | 1 |
| Saheki, T | 1 |
| Amat di San Filippo, C | 1 |
| Pasquali, M | 1 |
| Longo, N | 2 |
| Witte, KK | 1 |
| Clark, AL | 1 |
| Cruciani, RA | 1 |
| Dvorkin, E | 1 |
| Homel, P | 1 |
| Malamud, S | 1 |
| Culliney, B | 1 |
| Lapin, J | 1 |
| Portenoy, RK | 1 |
| Al-Majed, AA | 1 |
| Doberenz, J | 1 |
| Hirche, F | 1 |
| Keller, U | 1 |
| Eder, K | 1 |
| Donnelly, CT | 1 |
| Hameed, AB | 1 |
| Abdenur, JE | 1 |
| Wing, DA | 1 |
| Leschke, M | 1 |
| Rumpf, KW | 1 |
| Eisenhauer, T | 1 |
| Fuchs, C | 1 |
| Becker, K | 1 |
| Köthe, U | 1 |
| Scheler, F | 1 |
| Glasgow, AM | 1 |
| Eng, G | 1 |
| Engel, AG | 1 |
| Diep, QN | 1 |
| Bøhmer, T | 1 |
| Holme, JI | 1 |
| Torvik, A | 1 |
| Storrøsten, OT | 1 |
| Loennecken, CW | 1 |
| Monstad, P | 1 |
| Jellum, E | 1 |
| Lerner, A | 1 |
| Gruener, N | 1 |
| Iancu, TC | 1 |
| Borum, PR | 1 |
| Coulter, DL | 1 |
| Mintz, M | 1 |
| Winter, S | 1 |
| Jue, K | 1 |
| Prochazka, J | 1 |
| Francis, P | 1 |
| Hamilton, W | 1 |
| Linn, L | 1 |
| Helton, E | 1 |
| Pons, R | 1 |
| De Vivo, DC | 1 |
| Paulson, DJ | 1 |
| Lu, Km | 1 |
| Nishimori, H | 1 |
| Nakamura, Y | 1 |
| Shima, K | 1 |
| Kuwajima, M | 1 |
| Wang, Y | 1 |
| Ye, J | 1 |
| Ganapathy, V | 1 |
| Angelini, C | 2 |
| Bizzi, A | 1 |
| Cini, M | 1 |
| Garattini, S | 1 |
| Mingardi, G | 1 |
| Licini, L | 1 |
| Mecca, G | 1 |
| VanDyke, DH | 1 |
| Griggs, RC | 1 |
| Markesbery, W | 1 |
| Dimauro, S | 1 |
| Rudman, D | 1 |
| Sewell, CW | 1 |
| Ansley, JD | 1 |
| Vergani, L | 1 |
| Martinuzzi, A | 1 |
| De Simone, C | 1 |
| Tzantzoglou, S | 1 |
| Jirillo, E | 1 |
| Marzo, A | 1 |
| Vullo, V | 1 |
| Martelli, EA | 1 |
| Duran, M | 1 |
| Loof, NE | 1 |
| Ketting, D | 1 |
| Dorland, L | 1 |
| Gadzhiev, AA | 1 |
| Nartsissov, RP | 1 |
| Gashimova, RA | 1 |
| Gasanov, SSh | 1 |
| Lysiak-Szydłowska, W | 1 |
| Ino, T | 1 |
| Sherwood, WG | 1 |
| Benson, LN | 1 |
| Wilson, GJ | 1 |
| Freedom, RM | 1 |
| Rowe, RD | 1 |
| Shaw, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised, Double Blinded Cross-over Study Comparing the Efficacy of L-carnitine Versus Placebo in the Treatment of Fatigue in Multiple Sclerosis[NCT01149525] | Phase 3 | 59 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| Correlation Between Carnitine Deficiency and Hypoglycemic Events in Type I Diabetes; Effects of Carnitine Supplementation on Hypoglycemic Events in Type I Diabetes[NCT00351234] | 200 participants (Actual) | Observational | 2004-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for carnitine and Deficiency, Vitamin B
| Article | Year |
|---|---|
Mechanistic contribution of carnitine deficiency to geriatric frailty.
Topics: Aged; Aged, 80 and over; Aging; Carnitine; Frail Elderly; Humans; Vitamin B Deficiency | 2010 |
L-Carnitine and intestinal inflammation.
Topics: Animals; Carnitine; Dietary Supplements; Gastroenteritis; Humans; Immunosuppression Therapy; Intesti | 2011 |
Science review: carnitine in the treatment of valproic acid-induced toxicity - what is the evidence?
Topics: Anticonvulsants; Carnitine; Chemical and Drug Induced Liver Injury; Drug Overdose; Hepatic Encephalo | 2005 |
The use of levo-carnitine in children with renal disease: a review and a call for future studies.
Topics: Anemia; Carnitine; Child; Dyslipidemias; Humans; Kidney Diseases; Kidney Failure, Chronic; Stereoiso | 2006 |
Micronutrients and their supplementation in chronic cardiac failure. An update beyond theoretical perspectives.
Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Carnitine; Copper; Dietary Supplements; Heart Failure | 2006 |
Carnitine in neonatal nutrition.
Topics: Age Factors; Animals; Animals, Newborn; Carnitine; Child Nutritional Physiological Phenomena; Humans | 1995 |
Carnitine deficiency in epilepsy: Risk factors and treatment.
Topics: Carnitine; Epilepsy; Humans; Liver; Risk Factors; Valproic Acid; Vitamin B Deficiency | 1995 |
Carnitine in human immunodeficiency virus type 1 infection/acquired immune deficiency syndrome.
Topics: Carnitine; HIV Infections; HIV-1; Humans; Vitamin B Deficiency | 1995 |
Primary and secondary carnitine deficiency syndromes.
Topics: Animals; Carnitine; Enzyme Activation; Fatty Acids; Humans; Mitochondria; Risk Factors; Vitamin B De | 1995 |
Carnitine deficiency-induced cardiomyopathy.
Topics: Animals; Cardiomyopathies; Carnitine; Disease Models, Animal; Humans; Kinetics; Models, Biological; | 1998 |
Clinical and biochemical aspects of carnitine deficiency and insufficiency: transport defects and inborn errors of beta-oxidation.
Topics: Biological Transport, Active; Carnitine; Fatty Acids; Humans; Metabolism, Inborn Errors; Mitochondri | 1992 |
Secondary carnitine deficiency.
Topics: Adolescent; Carnitine; Child; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Vitamin B Def | 1990 |
[The physiological role of L-carnitine in the human body: causes and effects of its deficiency].
Topics: Adult; Carnitine; Child; Heart Failure; Humans; Muscular Diseases; Vitamin B Deficiency | 1988 |
1 trial available for carnitine and Deficiency, Vitamin B
| Article | Year |
|---|---|
Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study.
Topics: Administration, Oral; Carnitine; Dietary Supplements; Dose-Response Relationship, Drug; Drug Adminis | 2006 |
31 other studies available for carnitine and Deficiency, Vitamin B
| Article | Year |
|---|---|
Sodium valproate-induced Fanconi syndrome in two severely disabled patients receiving carnitine supplementation.
Topics: Adult; Anticonvulsants; Carnitine; Disabled Persons; Epilepsy; Fanconi Syndrome; Female; Humans; Int | 2019 |
Plasma carnitine concentrations after chronic alcohol intoxication.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Carnitine; Female; Humans; Male; Middle Aged; Plasma; Ref | 2013 |
Muscle carnitine deficiency: adult onset lipid storage myopathy with sensory neuropathy.
Topics: Adult; Carnitine; China; Humans; Lipid Metabolism Disorders; Male; Muscle, Skeletal; Muscular Diseas | 2010 |
The plasma carnitine concentration regulates renal OCTN2 expression and carnitine transport in rats.
Topics: Animals; Biological Transport; Carnitine; Cell Line; Cell Membrane; Gene Expression Regulation; Huma | 2010 |
Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.
Topics: Adult; Biomarkers; Biotin; Carnitine; Egg White; Female; Humans; Lymphocytes; Male; Methylmalonyl-Co | 2011 |
[Carnitine transporter deficiency is a hereditary disease with a high incidence in the Faroe Islands].
Topics: Adult; Carnitine; Child; Denmark; Founder Effect; Genetic Variation; Humans; Organic Cation Transpor | 2012 |
The mdx mouse as a model for carnitine deficiency in the pathogenesis of Duchenne muscular dystrophy.
Topics: Animals; Carnitine; Disease Models, Animal; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, | 2012 |
Whole-blood 3-hydroxyisovalerylcarnitine as a risk factor for orofacial clefts.
Topics: Biotin; Carnitine; Cleft Lip; Cleft Palate; Humans; Infant, Newborn; Poland; Retrospective Studies; | 2013 |
The effect of zinc and potassium in the nutrition of Tenebrio molitor, with observations on the expression of a carnitine deficiency.
Topics: Animals; Cardiomyopathies; Carnitine; Humans; Hyperammonemia; Muscular Diseases; Potassium; Tenebrio | 1958 |
Sodium valproate -- induced skeletal myopathy.
Topics: Anticonvulsants; Carbamazepine; Carnitine; Child, Preschool; Epilepsy; Humans; Male; Muscular Diseas | 2005 |
Attenuation of cardiac hypertrophy in carnitine-deficient juvenile visceral steatosis (JVS) mice achieved by lowering dietary lipid.
Topics: Animals; Aspirin; Carnitine; Diet; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Dr | 2006 |
Pharmacological rescue of carnitine transport in primary carnitine deficiency.
Topics: Adult; Animals; Biological Transport; Carnitine; Child, Preschool; CHO Cells; Cricetinae; Cricetulus | 2006 |
Carnitine deficiency provokes cisplatin-induced hepatotoxicity in rats.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti | 2007 |
Pivalate lowers litter sizes and weights in female rats independent of its effect on carnitine status.
Topics: Animals; Animals, Newborn; Body Weight; Carnitine; Female; Fertilization; Litter Size; Pentanoic Aci | 2007 |
[A severe disabled case of incomplete Fanconi syndrome after discontinuation of carnitine supplementation during valproate sodium therapy].
Topics: Anticonvulsants; Carnitine; Child; Disabled Children; Fanconi Syndrome; Female; Humans; Valproic Aci | 2007 |
Carnitine deficiency in pregnancy.
Topics: Adult; Carnitine; Cesarean Section; Female; Fibroblasts; Humans; Pregnancy; Pregnancy Complications; | 2007 |
Quantitative assessment of carnitine loss during hemodialysis and hemofiltration.
Topics: Adult; Blood; Carnitine; Female; Humans; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulato | 1983 |
Systemic carnitine deficiency simulating recurrent Reye syndrome.
Topics: Carnitine; Child; Child, Preschool; Diagnosis, Differential; Fasting; Humans; Infant; Reye Syndrome; | 1980 |
Slow replenishment of carnitine deficiency after cessation of long-term treatment with pivaloyl-containing antibiotics.
Topics: Adult; Aged; Aged, 80 and over; Amdinocillin Pivoxil; Carnitine; Child; Female; Humans; Male; Pivamp | 1993 |
Serum carnitine concentrations in coeliac disease.
Topics: Adolescent; Carnitine; Celiac Disease; Child; Child, Preschool; Duodenum; Female; Gastrointestinal D | 1993 |
The role of L-carnitine in pediatric cardiomyopathy.
Topics: Cardiomyopathies; Carnitine; Child; Child, Preschool; Female; Humans; Infant; Male; Retrospective St | 1995 |
A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carrier Proteins; Disease Models, Animal; DN | 1998 |
Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Carnitine; Carrier Proteins; Cell Line; | 1999 |
Letter: Carnitine deficiency.
Topics: Carnitine; Child; Female; Humans; Vitamin B Deficiency | 1975 |
L-carnitine addition to haemodialysis fluid prevents plasma-carnitine deficiency during dialysis.
Topics: Carnitine; Humans; Renal Dialysis; Vitamin B Deficiency | 1979 |
Hereditary carnitine deficiency of muscle.
Topics: Aspartate Aminotransferases; Biopsy; Cardiomegaly; Carnitine; Child; Creatine Kinase; Genes, Recessi | 1975 |
Deficiency of carnitine in cachectic cirrhotic patients.
Topics: Adult; Cachexia; Carnitine; Diet; Female; Hospitalization; Humans; Liver Cirrhosis; Lysine; Male; Me | 1977 |
L-carnitine deficiency in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Carnitine; Female; Humans; Male; Vitamin B Deficiency | 1992 |
[Correction of metabolic changes in neutrophils with carnitine chloride in newborn infants at risk of developing bacterial infections].
Topics: Administration, Oral; Bacterial Infections; Carnitine; Female; Humans; Infant, Newborn; Male; Neutro | 1990 |
Cardiac manifestations in disorders of fat and carnitine metabolism in infancy.
Topics: Biopsy; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Carnitine; Echocardiography; Electroc | 1988 |
Possible role of lysolecithins and nonesterified fatty acids in the pathogenesis of Reye's syndrome, sudden infant death syndrome, acute pancreatitis, and diabetic ketoacidosis.
Topics: Acute Disease; Barbiturates; Blood Transfusion; Carnitine; Diabetic Ketoacidosis; Fasting; Fatty Aci | 1985 |