carnitine has been researched along with Debility in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study tested the hypothesis that in human aging, a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance, and altered mitochondrial function." | 3.96 | Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males. ( Bos, P; Keijer, J; Kleemann, R; Kuda, O; Nieuwenhuizen, AG; Paluchová, V; van den Hoek, AM; van der Hoek, MD; van der Leij, FR; Veeger, NJGM; Verschuren, L, 2020) |
| "L-carnitine (LC) plays an important role in energy production from long-chain fatty acids in mitochondria, and its serum level is lower in prefrail and frail subjects." | 3.11 | Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial. ( Bertino, G; Bonfiglio, C; Castorina, M; Catania, VE; Cauli, O; Chisari, LM; Malaguarnera, G; Malaguarnera, M, 2022) |
| "Outcome measures include frailty status using Fried criteria and Frailty Index accumulation of deficit, selected frailty biomarkers (interleukin-6, tumor necrosis factor-alpha, and insulin-like growth factor-1), physical function, cognitive function, nutritional status and biochemical profile." | 2.82 | Efficacy of L-carnitine supplementation on frailty status and its biomarkers, nutritional status, and physical and cognitive function among prefrail older adults: a double-blind, randomized, placebo-controlled clinical trial. ( Badrasawi, M; Nor Fadilah, R; Shahar, S; Singh, DK; Zahara, AM, 2016) |
| "Frailty is an expression that reconciles and condenses loss of autonomy, both physical and cognitive decline and a wide spectrum of adverse outcomes due to aging." | 1.56 | Carnitine Serum Levels in Frail Older Subjects. ( Bertino, G; Bonfiglio, C; Catania, VE; Malaguarnera, G; Malaguarnera, M; Vicari, E, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Malaguarnera, G | 2 |
| Catania, VE | 2 |
| Bertino, G | 2 |
| Chisari, LM | 1 |
| Castorina, M | 1 |
| Bonfiglio, C | 2 |
| Cauli, O | 1 |
| Malaguarnera, M | 2 |
| Rattray, NJW | 1 |
| Trivedi, DK | 1 |
| Xu, Y | 1 |
| Chandola, T | 1 |
| Johnson, CH | 1 |
| Marshall, AD | 1 |
| Mekli, K | 1 |
| Rattray, Z | 1 |
| Tampubolon, G | 1 |
| Vanhoutte, B | 1 |
| White, IR | 1 |
| Wu, FCW | 1 |
| Pendleton, N | 1 |
| Nazroo, J | 1 |
| Goodacre, R | 1 |
| van der Hoek, MD | 1 |
| Nieuwenhuizen, AG | 1 |
| Kuda, O | 1 |
| Bos, P | 1 |
| Paluchová, V | 1 |
| Verschuren, L | 1 |
| van den Hoek, AM | 1 |
| Kleemann, R | 1 |
| Veeger, NJGM | 1 |
| van der Leij, FR | 1 |
| Keijer, J | 1 |
| Ng, TKS | 1 |
| Kovalik, JP | 1 |
| Ching, J | 1 |
| Chan, AW | 1 |
| Matchar, DB | 1 |
| Vicari, E | 1 |
| Nagai, K | 1 |
| Koshiba, H | 1 |
| Shibata, S | 1 |
| Hirasawa, A | 1 |
| Ebihara, T | 1 |
| Kozaki, K | 1 |
| Badrasawi, M | 1 |
| Shahar, S | 1 |
| Zahara, AM | 1 |
| Nor Fadilah, R | 1 |
| Singh, DK | 1 |
2 trials available for carnitine and Debility
| Article | Year |
|---|---|
Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
Topics: Acetylcarnitine; Aged; Aging; Carnitine; Double-Blind Method; Frailty; Humans | 2022 |
Efficacy of L-carnitine supplementation on frailty status and its biomarkers, nutritional status, and physical and cognitive function among prefrail older adults: a double-blind, randomized, placebo-controlled clinical trial.
Topics: Aged; Biomarkers; Carnitine; Cognition; Dietary Supplements; Double-Blind Method; Female; Frailty; H | 2016 |
5 other studies available for carnitine and Debility
| Article | Year |
|---|---|
Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty.
Topics: Aged; Aging; Carnitine; Confounding Factors, Epidemiologic; Discriminant Analysis; Energy Metabolism | 2019 |
Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males.
Topics: Aged; Aged, 80 and over; Aging; Carnitine; Cross-Sectional Studies; Female; Frail Elderly; Frailty; | 2020 |
Novel metabolomics markers are associated with pre-clinical decline in hand grip strength in community-dwelling older adults.
Topics: Aged; Aging; Asymptomatic Diseases; Biomarkers; Carnitine; Energy Metabolism; Fatty Acids; Female; F | 2021 |
Carnitine Serum Levels in Frail Older Subjects.
Topics: Aged; Aged, 80 and over; Carnitine; Cross-Sectional Studies; Female; Frail Elderly; Frailty; Geriatr | 2020 |
Relationship of Serum Carnitine Level with Falls and Gait Disturbance in the Elderly.
Topics: Accidental Falls; Aged; Aged, 80 and over; Carnitine; Cross-Sectional Studies; Female; Frail Elderly | 2017 |