Page last updated: 2024-10-16

carnitine and Critical Illness

carnitine has been researched along with Critical Illness in 18 studies

Critical Illness: A disease or state in which death is possible or imminent.

Research Excerpts

ExcerptRelevanceReference
" Both levocarnitine and lactulose, either alone or in combination, have been used for the treatment of hyperammonemia associated with valproic acid, however they have not been directly compared in the literature."8.02Evaluation of levocarnitine, lactulose, and combination therapy for the treatment of valproic acid-induced hyperammonemia in critically ill patients. ( Cunningham, B; Fowler, M; Mullen, C; Nicholson, C, 2021)
" We investigated the effects of L-carnitine adjunctive therapy on monitoring variables in critical illness."5.69The effects of adjunctive treatment with L-carnitine on monitoring laboratory variables in ICU patients: a double-blinded randomized controlled clinical trial. ( Badpeyma, M; Bagherniya, M; Clark, CCT; Feizi, A; Keshani, M; Norouzy, A; Safarian, M; Sedaghat, A; Yahyapoor, F, 2023)
"The aim of this study was to evaluate to what extent secondary carnitine deficiency may exist based on the prevalence of subnormal carnitine status in patients with critical illness and abnormal nutritional state."5.07Prevalence of carnitine depletion in critically ill patients with undernutrition. ( Arfvidsson, B; Hyltander, A; Lundholm, K; Sandström, R; Sjöberg, A; Wennberg, A; Wickström, I, 1992)
" This article reviews some of the pharmacologic roles that parenteral nutritional ingredients (selenium, lipid emulsion, insulin, and levocarnitine) can play in the setting of critical illness."4.90Nutrition as medical therapy. ( DiNapoli, M; Miller, MA; Ross, B; Yogaratnam, D, 2014)
" Perioperative metabolic conditioning using glutamine and L-carnitine may be used to modulate insulin sensitivity but further studies need to determine whether these interventions result in clinical benefit."4.88Metabolic conditioning to attenuate the adverse effects of perioperative fasting and improve patient outcomes. ( Awad, S; Lobo, DN, 2012)
" The aim of this study was to describe and compare the prevalence of micronutrient and carnitine deficiencies in critically ill patients at high malnutrition risk exposed to CRRT to a group of patient unexposed to CRRT."4.12Micronutrient deficiencies in critically ill patients receiving continuous renal replacement therapy. ( Fah, M; Haines, KL; Krishnamoorthy, V; Ohnuma, T; Raghunathan, K; Van Althuis, LE; Williams, DGA; Winthrop, HM; Wischmeyer, PE, 2022)
" Both levocarnitine and lactulose, either alone or in combination, have been used for the treatment of hyperammonemia associated with valproic acid, however they have not been directly compared in the literature."4.02Evaluation of levocarnitine, lactulose, and combination therapy for the treatment of valproic acid-induced hyperammonemia in critically ill patients. ( Cunningham, B; Fowler, M; Mullen, C; Nicholson, C, 2021)
"l-Carnitine (3000 mg/day) was administered via nasogastric tube for the intervention group for 7 days, while the other group received a placebo for the same duration."3.11The effects of l-Carnitine supplementation on inflammatory markers, clinical status, and 28 days mortality in critically ill patients: A double-blind, randomized, placebo-controlled trial. ( Arabi, SM; Bagherniya, M; Feizi, A; Islam, MS; Khadem-Rezaiyan, M; Norouzy, A; Pahlavani, N; Safarian, M; Sedaghat, A; Yahyapoor, F; Zarifi, SH, 2022)
"Carnitine is a small molecule essential for fatty acid oxidation and gluconeogenesis."1.62Carnitine deficiency among hospitalized pediatric patients: A retrospective study of critically ill patients receiving extracorporeal membrane oxygenation therapy. ( Kelley, J; Kellogg, K; Norris, M; Parietti, J; Scott, AI; Sullivan, E; Sullivan, S, 2021)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's4 (22.22)18.2507
2000's0 (0.00)29.6817
2010's7 (38.89)24.3611
2020's6 (33.33)2.80

Authors

AuthorsStudies
Nicholson, C1
Fowler, M1
Mullen, C1
Cunningham, B1
Yahyapoor, F2
Sedaghat, A2
Feizi, A2
Bagherniya, M2
Pahlavani, N1
Khadem-Rezaiyan, M1
Safarian, M2
Islam, MS1
Zarifi, SH1
Arabi, SM1
Norouzy, A2
Fah, M1
Van Althuis, LE1
Ohnuma, T1
Winthrop, HM1
Haines, KL1
Williams, DGA1
Krishnamoorthy, V1
Raghunathan, K1
Wischmeyer, PE1
Keshani, M1
Clark, CCT1
Badpeyma, M1
Wilkinson, D1
Gallagher, IJ1
McNelly, A1
Bear, DE1
Hart, N1
Montgomery, HE1
Le Guennec, A1
Conte, MR1
Francis, T1
Harridge, SDR1
Atherton, PJ1
Puthucheary, ZA1
Kelley, J1
Sullivan, E1
Norris, M1
Sullivan, S1
Parietti, J1
Kellogg, K1
Scott, AI1
Giva, S1
Finnegan, J1
Ihidero, P1
Maguire, G1
Power, B1
Knerr, I1
Monavari, A1
Casaer, MP1
Bellomo, R1
Bonafé, L1
Berger, MM1
Que, YA1
Mechanick, JI1
Yogaratnam, D1
Miller, MA1
Ross, B1
DiNapoli, M1
Zhou, Z1
Qiu, C2
Chen, C2
Wang, L1
Chen, J2
Chen, M2
Guan, X2
Ouyang, B2
Zhang, W1
Kou, Q1
Wu, S1
Zhou, L1
Liu, J1
Ma, G1
Luo, H1
Zhang, X1
Lai, J1
Yu, Z1
Yu, X1
Liao, W1
Awad, S1
Lobo, DN1
Ball, MJ1
Proulx, F1
Lacroix, J1
Qureshi, IA1
Nadeau, D1
Gauthier, M1
Lambert, M1
Nijveldt, RJ1
Tan, AM1
Prins, HA1
de Jong, D1
van Rij, GL1
Wesdorp, RI1
van Leeuwen, PA1
Wennberg, A1
Hyltander, A1
Sjöberg, A1
Arfvidsson, B1
Sandström, R1
Wickström, I1
Lundholm, K1
Scholten, DJ1
Davis, AT1
Albrecht, RM1
Morgan, RE1

Reviews

3 reviews available for carnitine and Critical Illness

ArticleYear
Carnitine deficiency in chronic critical illness.
    Current opinion in clinical nutrition and metabolic care, 2014, Volume: 17, Issue:2

    Topics: Cardiomyopathies; Carnitine; Chronic Disease; Critical Illness; Fatty Acids; Humans; Hyperammonemia;

2014
Nutrition as medical therapy.
    Critical care nursing clinics of North America, 2014, Volume: 26, Issue:2

    Topics: Carnitine; Critical Care Nursing; Critical Illness; Humans; Insulin; Lipids; Nutrition Therapy; Pare

2014
Metabolic conditioning to attenuate the adverse effects of perioperative fasting and improve patient outcomes.
    Current opinion in clinical nutrition and metabolic care, 2012, Volume: 15, Issue:2

    Topics: Arginine; Carbohydrate Metabolism; Carnitine; Critical Illness; Dietary Supplements; Elective Surgic

2012

Trials

7 trials available for carnitine and Critical Illness

ArticleYear
The effects of l-Carnitine supplementation on inflammatory markers, clinical status, and 28 days mortality in critically ill patients: A double-blind, randomized, placebo-controlled trial.
    Clinical nutrition ESPEN, 2022, Volume: 49

    Topics: Biomarkers; C-Reactive Protein; Carnitine; Critical Illness; Dietary Supplements; Humans; Interleuki

2022
The effects of adjunctive treatment with L-carnitine on monitoring laboratory variables in ICU patients: a double-blinded randomized controlled clinical trial.
    Trials, 2023, Jan-03, Volume: 24, Issue:1

    Topics: Carnitine; COVID-19; Critical Illness; Humans; Intensive Care Units; Iran; Lactates; Prospective Stu

2023
The metabolic effects of intermittent versus continuous feeding in critically ill patients.
    Scientific reports, 2023, 11-09, Volume: 13, Issue:1

    Topics: Alanine; Amino Acids; Carnitine; Critical Illness; Humans; Ketones

2023
Fat-Modified Enteral Formula Improves Feeding Tolerance in Critically Ill Patients: A Multicenter, Single-Blind, Randomized Controlled Trial.
    JPEN. Journal of parenteral and enteral nutrition, 2017, Volume: 41, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Bilir

2017
Parenteral nutrition in the critically ill: use of a medium chain triglyceride emulsion.
    Intensive care medicine, 1993, Volume: 19, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Blood Cell Count; Carnitine; Critical Illness; Dr

1993
Use of a mixture of medium-chain triglycerides and longchain triglycerides versus long-chain triglycerides in critically ill surgical patients: a randomized prospective double-blind study.
    Clinical nutrition (Edinburgh, Scotland), 1998, Volume: 17, Issue:1

    Topics: Adult; Aged; Bilirubin; Carnitine; Critical Illness; Double-Blind Method; Energy Intake; Energy Meta

1998
Prevalence of carnitine depletion in critically ill patients with undernutrition.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:2

    Topics: Aged; Carnitine; Critical Illness; Female; Hemofiltration; Humans; Kidney Diseases; Liver Diseases;

1992

Other Studies

8 other studies available for carnitine and Critical Illness

ArticleYear
Evaluation of levocarnitine, lactulose, and combination therapy for the treatment of valproic acid-induced hyperammonemia in critically ill patients.
    Epilepsy research, 2021, Volume: 178

    Topics: Carnitine; Cohort Studies; Critical Illness; Humans; Hyperammonemia; Lactulose; Retrospective Studie

2021
Micronutrient deficiencies in critically ill patients receiving continuous renal replacement therapy.
    Clinical nutrition ESPEN, 2022, Volume: 50

    Topics: Carnitine; Continuous Renal Replacement Therapy; Copper; Critical Illness; Humans; Malnutrition; Mic

2022
Carnitine deficiency among hospitalized pediatric patients: A retrospective study of critically ill patients receiving extracorporeal membrane oxygenation therapy.
    JPEN. Journal of parenteral and enteral nutrition, 2021, Volume: 45, Issue:8

    Topics: Carnitine; Child; Critical Illness; Extracorporeal Membrane Oxygenation; Humans; Infant; Malnutritio

2021
Hyperammonaemia in Neonates and Young Children: Potential Metabolic Causes, Diagnostic Approaches and Clinical Consequences
    Irish medical journal, 2019, 01-15, Volume: 112, Issue:1

    Topics: Ammonia; Arginine; Biomarkers; Brain Diseases, Metabolic, Inborn; Carnitine; Critical Illness; Diet,

2019
Micronutrient deficiency in critical illness: an invisible foe?
    Intensive care medicine, 2019, Volume: 45, Issue:8

    Topics: Ascorbic Acid Deficiency; Carnitine; Critical Illness; Folic Acid; Humans; Micronutrients; Nutrition

2019
[Related factor of serum carnitine deficiency and influence of its deficiency on the length of hospital stay in critical ill patients].
    Zhonghua wei zhong bing ji jiu yi xue, 2014, Volume: 26, Issue:12

    Topics: APACHE; Bilirubin; Carnitine; Critical Illness; Enteral Nutrition; Hospital Mortality; Humans; Inten

2014
Acquired carnitine abnormalities in critically ill children.
    European journal of pediatrics, 1997, Volume: 156, Issue:11

    Topics: Adolescent; Biomarkers; Carnitine; Child; Child, Preschool; Critical Illness; Energy Intake; Female;

1997
Carnitine femoral arterial-venous differences in the stressed critically ill.
    Journal of the American College of Nutrition, 1989, Volume: 8, Issue:2

    Topics: Adult; Aged; Carnitine; Critical Illness; Female; Femoral Artery; Femoral Vein; Humans; Male; Middle

1989