carnitine has been researched along with Coronary Artery Disease in 18 studies
Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "l-Carnitine has been suggested as a potential nutrient that alleviates the oxidative and inflammatory damages of coronary artery disease (CAD), but the results of the previous studies of the importance of this supplementation remains unclear." | 9.69 | L-Carnitine supplementation reduces biomarkers of inflammatory and oxidative stress in patients with coronary artery disease: a randomised controlled trial. ( Heidari Moghaddam, R; Moludi, J; Mostafai, R; Nachvak, SM; Shabanpur, M, 2023) |
| " The levels of LC, antioxidant status (malondialdehyde and antioxidant enzymes activities), and inflammation markers (C-reactive protein [CRP], interleukin [IL]-6, and tumor necrosis factor [TNF]-α) were measured." | 9.20 | Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients. ( Lee, BJ; Lin, JS; Lin, PT; Lin, YC, 2015) |
| " We hypothesize that short-chain acylcarnitines (SCA) reflect the link between FDP intake and angiographic extent of stable coronary artery disease (CAD)." | 7.96 | Relationship between fermented dairy consumption, circulating short-chain acylcarnitines and angiographic severity of coronary artery disease. ( Beutner, F; Burkhardt, R; Ceglarek, U; Gielen, S; Scholz, M; Teren, A; Thiery, J; Vogel, A, 2020) |
| "L-carnitine (LC) plays an important physiologic role in lipid metabolism." | 6.82 | Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease. ( Lee, BJ; Lin, JS; Lin, PT; Lin, YC, 2016) |
| "l-Carnitine has been suggested as a potential nutrient that alleviates the oxidative and inflammatory damages of coronary artery disease (CAD), but the results of the previous studies of the importance of this supplementation remains unclear." | 5.69 | L-Carnitine supplementation reduces biomarkers of inflammatory and oxidative stress in patients with coronary artery disease: a randomised controlled trial. ( Heidari Moghaddam, R; Moludi, J; Mostafai, R; Nachvak, SM; Shabanpur, M, 2023) |
| " The levels of LC, antioxidant status (malondialdehyde and antioxidant enzymes activities), and inflammation markers (C-reactive protein [CRP], interleukin [IL]-6, and tumor necrosis factor [TNF]-α) were measured." | 5.20 | Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients. ( Lee, BJ; Lin, JS; Lin, PT; Lin, YC, 2015) |
| " Specifically, we used genetic variants to predict L-carnitine, and obtained their associations with coronary artery disease (CAD), ischemic stroke, heart failure, and atrial fibrillation, as well as CVD risk factors (type 2 diabetes, glucose, HbA1c, insulin, lipid profile, blood pressure and body mass index) in large consortia and established cohorts, as well as sex-specific association in the UK Biobank." | 4.12 | L-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study. ( Burgess, S; Fan, B; Schooling, CM; Zhao, JV, 2022) |
| " We hypothesize that short-chain acylcarnitines (SCA) reflect the link between FDP intake and angiographic extent of stable coronary artery disease (CAD)." | 3.96 | Relationship between fermented dairy consumption, circulating short-chain acylcarnitines and angiographic severity of coronary artery disease. ( Beutner, F; Burkhardt, R; Ceglarek, U; Gielen, S; Scholz, M; Teren, A; Thiery, J; Vogel, A, 2020) |
| "L-carnitine (LC) plays an important physiologic role in lipid metabolism." | 2.82 | Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease. ( Lee, BJ; Lin, JS; Lin, PT; Lin, YC, 2016) |
| " We examined whether metabolic profiles can predict adverse events in patients undergoing coronary artery bypass grafting." | 1.38 | Metabolic profiles predict adverse events after coronary artery bypass grafting. ( Craig, DM; Granger, CB; Hauser, ER; Haynes, C; Hughes, GC; Kraus, WE; Muehlbauer, MJ; Newby, LK; Newgard, CB; Sebek, JK; Shah, AA; Shah, SH; Stevens, RC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 7 (38.89) | 2.80 |
| Authors | Studies |
|---|---|
| Adebayo, AS | 1 |
| Roman, M | 1 |
| Zakkar, M | 1 |
| Yusoff, S | 1 |
| Gulston, M | 1 |
| Joel-David, L | 1 |
| Anthony, B | 1 |
| Lai, FY | 1 |
| Murgia, A | 1 |
| Eagle-Hemming, B | 1 |
| Sheikh, S | 1 |
| Kumar, T | 1 |
| Aujla, H | 1 |
| Dott, W | 1 |
| Griffin, JL | 1 |
| Murphy, GJ | 1 |
| Woźniak, MJ | 1 |
| Amrein, M | 1 |
| Li, XS | 1 |
| Walter, J | 1 |
| Wang, Z | 1 |
| Zimmermann, T | 1 |
| Strebel, I | 1 |
| Honegger, U | 1 |
| Leu, K | 1 |
| Schäfer, I | 1 |
| Twerenbold, R | 1 |
| Puelacher, C | 1 |
| Glarner, N | 1 |
| Nestelberger, T | 1 |
| Koechlin, L | 1 |
| Ceresa, B | 1 |
| Haaf, P | 1 |
| Bakula, A | 1 |
| Zellweger, M | 1 |
| Hazen, SL | 1 |
| Mueller, C | 1 |
| Deda, O | 1 |
| Panteris, E | 1 |
| Meikopoulos, T | 1 |
| Begou, O | 1 |
| Mouskeftara, T | 1 |
| Karagiannidis, E | 1 |
| Papazoglou, AS | 1 |
| Sianos, G | 1 |
| Theodoridis, G | 1 |
| Gika, H | 1 |
| Hosseinkhani, S | 1 |
| Emamgholipour, S | 1 |
| Salari, P | 1 |
| Khalagi, K | 1 |
| Shirani, S | 1 |
| Najjar, N | 1 |
| Larijani, B | 1 |
| Pasalar, P | 1 |
| Razi, F | 1 |
| Zhao, JV | 1 |
| Burgess, S | 1 |
| Fan, B | 1 |
| Schooling, CM | 1 |
| Beuchel, C | 1 |
| Becker, S | 1 |
| Dittrich, J | 1 |
| Kirsten, H | 1 |
| Toenjes, A | 1 |
| Stumvoll, M | 1 |
| Loeffler, M | 1 |
| Thiele, H | 1 |
| Beutner, F | 2 |
| Thiery, J | 2 |
| Ceglarek, U | 2 |
| Scholz, M | 2 |
| Teren, A | 1 |
| Vogel, A | 1 |
| Gielen, S | 1 |
| Burkhardt, R | 1 |
| Nachvak, SM | 1 |
| Shabanpur, M | 1 |
| Mostafai, R | 1 |
| Heidari Moghaddam, R | 1 |
| Moludi, J | 1 |
| Strand, E | 1 |
| Rebnord, EW | 1 |
| Flygel, MR | 1 |
| Lysne, V | 1 |
| Svingen, GFT | 1 |
| Tell, GS | 1 |
| Løland, KH | 1 |
| Berge, RK | 2 |
| Svardal, A | 2 |
| Nygård, O | 1 |
| Pedersen, ER | 1 |
| Trøseid, M | 1 |
| Mayerhofer, CCK | 1 |
| Broch, K | 1 |
| Arora, S | 1 |
| Hov, JR | 1 |
| Andreassen, AK | 1 |
| Gude, E | 1 |
| Karason, K | 1 |
| Dellgren, G | 1 |
| Gullestad, L | 1 |
| Aukrust, P | 1 |
| Ueland, T | 1 |
| Lee, BJ | 3 |
| Lin, JS | 3 |
| Lin, YC | 3 |
| Lin, PT | 3 |
| Aldemir, M | 1 |
| Pektaş, MB | 1 |
| Parlar, Aİ | 1 |
| Akcı, Ö | 1 |
| Emren, SV | 1 |
| Tecer, E | 1 |
| Adalı, F | 1 |
| Yüksel, Ş | 1 |
| Darçın, OT | 1 |
| César, LA | 1 |
| Gowdak, LH | 1 |
| Mansur, AP | 1 |
| Turer, AT | 1 |
| Stevens, RD | 1 |
| Bain, JR | 1 |
| Muehlbauer, MJ | 2 |
| van der Westhuizen, J | 1 |
| Mathew, JP | 1 |
| Schwinn, DA | 1 |
| Glower, DD | 1 |
| Newgard, CB | 2 |
| Podgoreanu, MV | 1 |
| Shah, AA | 1 |
| Craig, DM | 1 |
| Sebek, JK | 1 |
| Haynes, C | 1 |
| Stevens, RC | 1 |
| Granger, CB | 1 |
| Hauser, ER | 1 |
| Newby, LK | 1 |
| Kraus, WE | 1 |
| Hughes, GC | 1 |
| Shah, SH | 1 |
| Dalessandri, KM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Observational Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery[NCT02908009] | 80 participants (Anticipated) | Observational | 2016-09-09 | Recruiting | |||
| BASEL VIII Trial - Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia[NCT01838148] | 4,000 participants (Anticipated) | Observational | 2004-05-31 | Recruiting | |||
| Correlation of Clinical Types and Complexity of Coronary Artery Disease With Patients' Metabolic Profile[NCT04580173] | 1,050 participants (Anticipated) | Observational [Patient Registry] | 2019-07-12 | Recruiting | |||
| Observational Study for Identification of Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study (LE-Heart)[NCT00497887] | 4,000 participants (Anticipated) | Observational | 2006-12-31 | Recruiting | |||
| A Randomised Double Blind Study of the Effects of Homocysteine Lowering Therapy on Mortality and Cardiac Events in Patients Undergoing Coronary Angiography[NCT00354081] | Phase 3 | 3,096 participants (Actual) | Interventional | 1999-04-30 | Completed | ||
| [NCT01819701] | Phase 2/Phase 3 | 47 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Estudio clínico Fase III Para Evaluar la Eficacia terapéutica en Pacientes Mexicanos Con Dislipidemia Mediante el Uso vía Oral de L-Carnitina + Atorvastatina Comparado Con Atorvastatina[NCT03696940] | Phase 3 | 120 participants (Actual) | Interventional | 2018-05-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for carnitine and Coronary Artery Disease
| Article | Year |
|---|---|
The metabolic treatment of patients with coronary artery disease: effects on quality of life and effort angina.
Topics: Acetanilides; Angina Pectoris; Animals; Carnitine; Clinical Trials as Topic; Coronary Artery Disease | 2009 |
5 trials available for carnitine and Coronary Artery Disease
| Article | Year |
|---|---|
L-Carnitine supplementation reduces biomarkers of inflammatory and oxidative stress in patients with coronary artery disease: a randomised controlled trial.
Topics: Antioxidants; Biomarkers; C-Reactive Protein; Carnitine; Coronary Artery Disease; Dietary Supplement | 2023 |
Effects of L-carnitine supplementation on oxidative stress and antioxidant enzymes activities in patients with coronary artery disease: a randomized, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Antioxidants; Biomarkers; Body Mass Index; Carnitine; Catalase; Cholesterol | 2014 |
Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antioxidants; Biomarkers; C-Reactive Protein; Car | 2015 |
L-Carnitine Supplementation Reduces Short-Term Neutrophil-Lymphocyte Ratio in Patients Undergoing Coronary Artery Bypass Grafting.
Topics: Aged; Carnitine; Coronary Artery Bypass; Coronary Artery Disease; Double-Blind Method; Female; Human | 2015 |
Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease.
Topics: Aged; Aged, 80 and over; Apolipoprotein A-I; Apolipoproteins B; Cardiac Catheterization; Carnitine; | 2016 |
Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease.
Topics: Aged; Aged, 80 and over; Apolipoprotein A-I; Apolipoproteins B; Cardiac Catheterization; Carnitine; | 2016 |
Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease.
Topics: Aged; Aged, 80 and over; Apolipoprotein A-I; Apolipoproteins B; Cardiac Catheterization; Carnitine; | 2016 |
Effects of L-carnitine supplementation on lipid profiles in patients with coronary artery disease.
Topics: Aged; Aged, 80 and over; Apolipoprotein A-I; Apolipoproteins B; Cardiac Catheterization; Carnitine; | 2016 |
12 other studies available for carnitine and Coronary Artery Disease
| Article | Year |
|---|---|
Gene and metabolite expression dependence on body mass index in human myocardium.
Topics: Aged; Aged, 80 and over; Body Mass Index; Carnitine; Case-Control Studies; Cholesterol; Cohort Studi | 2022 |
Gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and cardiovascular risk in patients with suspected functionally relevant coronary artery disease (fCAD).
Topics: Betaine; Cardiovascular Diseases; Carnitine; Choline; Coronary Artery Disease; Gastrointestinal Micr | 2022 |
Correlation of Serum Acylcarnitines with Clinical Presentation and Severity of Coronary Artery Disease.
Topics: Biomarkers; Carnitine; Coronary Artery Disease; Humans; Prospective Studies; ST Elevation Myocardial | 2022 |
Evaluating the association between amino acid and acylcarnitine profiles and different levels of coronary artery disease risk in postmenopausal women using targeted metabolomics technique.
Topics: Amino Acids; Biomarkers; Carnitine; Coronary Angiography; Coronary Artery Disease; Cross-Sectional S | 2022 |
L-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study.
Topics: Cardiovascular Diseases; Carnitine; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Geno | 2022 |
Clinical and lifestyle related factors influencing whole blood metabolite levels - A comparative analysis of three large cohorts.
Topics: Adult; Aged; Amino Acids; Carnitine; Chromatography, High Pressure Liquid; Cohort Studies; Coronary | 2019 |
Relationship between fermented dairy consumption, circulating short-chain acylcarnitines and angiographic severity of coronary artery disease.
Topics: Aged; Biomarkers; Carnitine; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Cross | 2020 |
Serum Carnitine Metabolites and Incident Type 2 Diabetes Mellitus in Patients With Suspected Stable Angina Pectoris.
Topics: Aged; Angina, Stable; Betaine; Body Mass Index; Carnitine; Chromatography, Liquid; Coronary Artery D | 2018 |
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection.
Topics: Acute Disease; Adult; Aged; Betaine; Carnitine; Coronary Artery Disease; Cyclosporine; Everolimus; F | 2019 |
Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.
Topics: Aged; Anaerobic Threshold; Cardiac Output; Cardiopulmonary Bypass; Carnitine; Coronary Artery Diseas | 2009 |
Metabolic profiles predict adverse events after coronary artery bypass grafting.
Topics: Aged; Biomarkers; Carnitine; Coronary Artery Bypass; Coronary Artery Disease; Energy Metabolism; Fem | 2012 |
Multiple Methods for Reduction of Lipoprotein(a).
Topics: Ascorbic Acid; Carnitine; Coronary Artery Disease; Diet, Reducing; Estrogens; Exercise; Female; Huma | 2002 |